NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1314861348|gb|AUG18162|]
View 

RNA polymerase sigma factor RpoH [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

RNA polymerase sigma factor RpoH( domain architecture ID 11482333)

RNA polymerase sigma factor RpoH is involved in regulating the expression of heat shock genes; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released

Gene Ontology:  GO:0016987|GO:0003677|GO:0006352
PubMed:  3315851|3052291

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
PRK06596 PRK06596
RNA polymerase factor sigma-32; Reviewed
1-284 0e+00

RNA polymerase factor sigma-32; Reviewed


:

Pssm-ID: 235838 [Multi-domain]  Cd Length: 284  Bit Score: 539.76  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348   1 MTDKMQSLALAPVGNLDSYIRAANAWPMLSADEERALAEKLHYHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQ 80
Cdd:PRK06596    1 MTKALQLLALSPEGNLDAYIQAVNKIPMLTAEEEYMLAKRLREHGDLEAAKQLVLSHLRFVVHIARGYRGYGLPQADLIQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  81 EGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARE 160
Cdd:PRK06596   81 EGNIGLMKAVKRFDPEVGVRLVSFAVHWIKAEIHEYILRNWRIVKVATTKAQRKLFFNLRKAKKRLGWLNPEEVEMVAEE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 161 LGVTSKDVREMESRMAAQDMTFDLsSDDDSDSQPMAPVLYLQDKSSNFADGIEDDNWEEQAANRLTDAMQGLDERSQDII 240
Cdd:PRK06596  161 LGVSEEEVREMESRLSGQDASLDA-PIDDDDEESGAPQDYLEDKSSDPADVLEEDNWEDQRRALLADALEGLDERSRDII 239
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1314861348 241 RARWLDeDNKSTLQELADRYGVSAERVRQLEKNAMKKLRAAIEA 284
Cdd:PRK06596  240 EARWLD-DDKSTLQELAAEYGVSAERVRQIEKNAMKKLKAAIEA 282
 
Name Accession Description Interval E-value
PRK06596 PRK06596
RNA polymerase factor sigma-32; Reviewed
1-284 0e+00

RNA polymerase factor sigma-32; Reviewed


Pssm-ID: 235838 [Multi-domain]  Cd Length: 284  Bit Score: 539.76  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348   1 MTDKMQSLALAPVGNLDSYIRAANAWPMLSADEERALAEKLHYHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQ 80
Cdd:PRK06596    1 MTKALQLLALSPEGNLDAYIQAVNKIPMLTAEEEYMLAKRLREHGDLEAAKQLVLSHLRFVVHIARGYRGYGLPQADLIQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  81 EGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARE 160
Cdd:PRK06596   81 EGNIGLMKAVKRFDPEVGVRLVSFAVHWIKAEIHEYILRNWRIVKVATTKAQRKLFFNLRKAKKRLGWLNPEEVEMVAEE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 161 LGVTSKDVREMESRMAAQDMTFDLsSDDDSDSQPMAPVLYLQDKSSNFADGIEDDNWEEQAANRLTDAMQGLDERSQDII 240
Cdd:PRK06596  161 LGVSEEEVREMESRLSGQDASLDA-PIDDDDEESGAPQDYLEDKSSDPADVLEEDNWEDQRRALLADALEGLDERSRDII 239
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1314861348 241 RARWLDeDNKSTLQELADRYGVSAERVRQLEKNAMKKLRAAIEA 284
Cdd:PRK06596  240 EARWLD-DDKSTLQELAAEYGVSAERVRQIEKNAMKKLKAAIEA 282
rpoH_proteo TIGR02392
alternative sigma factor RpoH; A sigma factor is a DNA-binding protein protein that binds to ...
14-284 1.40e-167

alternative sigma factor RpoH; A sigma factor is a DNA-binding protein protein that binds to the DNA-directed RNA polymerase core to produce the holoenzyme capable of initiating transcription at specific sites. Different sigma factors act in vegetative growth, heat shock, extracytoplasmic functions (ECF), etc. This model represents the clade of sigma factors called RpoH and further restricted to the Proteobacteria. This protein may be called sigma-32, sigma factor H, heat shock sigma factor, and alternative sigma factor RpoH. Note that in some species the single locus rpoH may be replaced by two or more differentially regulated stress response sigma factors. [Cellular processes, Adaptations to atypical conditions, Transcription, Transcription factors]


Pssm-ID: 274107 [Multi-domain]  Cd Length: 270  Bit Score: 464.83  E-value: 1.40e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  14 GNLDSYIRAANAWPMLSADEERALAEKLHYHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRF 93
Cdd:TIGR02392   1 GSLDAYIRAVNRIPMLTPEEEYQLAKRLREHGDLDAAKKLVLSHLRFVVKIARGYRGYGLPQADLIQEGNIGLMKAVKRF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  94 NPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRL-GWFNQDEVEMVARELGVTSKDVREME 172
Cdd:TIGR02392  81 DPERGVRLVSFAVHWIKAEIHEYILRNWRLVKVATTKAQRKLFFNLRKMKKRLqGWLNPEEVEAIAEELGVSEREVREME 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 173 SRMAAQDMTFDLSSDDDSDSQPmAPVLYLQDKSSNFADGIEDDNWEEQAANRLTDAMQGLDERSQDIIRARWLDEDnKST 252
Cdd:TIGR02392 161 SRLSGQDMSLNASIDDDEDDGG-APIAYLVDKRSDPEDTLEEEQWEELQRQALANALGSLDARSRRIIEARWLDDD-KLT 238
                         250       260       270
                  ....*....|....*....|....*....|..
gi 1314861348 253 LQELADRYGVSAERVRQLEKNAMKKLRAAIEA 284
Cdd:TIGR02392 239 LQELAAEYGVSAERIRQIEKNAMKKLKAALAA 270
RpoD COG0568
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA ...
18-284 7.10e-109

DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440334 [Multi-domain]  Cd Length: 268  Bit Score: 315.84  E-value: 7.10e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  18 SYIRAANAWPMLSADEERALAEKLHyHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEV 97
Cdd:COG0568     1 AYLREIGRVPLLTAEEEVELARRIQ-AGDEEAKRKLVEANLRLVVSIAKKYQGRGLPLLDLIQEGNLGLMKAVEKFDPER 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  98 GVRLVSFAVHWIKAEIHEYVLRNWRIVKVATTKAQ--RKlffnLRKTKQRL--GWFNQDEVEMVARELGVTSKDVREMEs 173
Cdd:COG0568    80 GFRFSTYATWWIRQAITRAIADQWRTIRLPVHMAEtlNK----LRRAKRQLlqELGREPTPEEIAEELGVPEEKVREML- 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 174 RMAAQDMTFDlssdddsdsqpmAPVlyLQDKSSNFADGIEDDNW---EEQAANR-----LTDAMQGLDERSQDIIRARW- 244
Cdd:COG0568   155 RLAREPVSLD------------APV--GDDEDSELGDLLEDEEApspEEALEEEllreeLREALDTLTEREREILRLRFg 220
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1314861348 245 LDEDNKSTLQELADRYGVSAERVRQLEKNAMKKLRAAIEA 284
Cdd:COG0568   221 LDDGEPHTLEEIGKEFGVSRERVRQIEAKALRKLRHPLRS 260
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
53-123 3.88e-17

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 74.16  E-value: 3.88e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1314861348  53 LILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRI 123
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERGVSFSTWLYTIIRNAIIDYLRKQRRT 71
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
223-279 1.97e-10

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 55.19  E-value: 1.97e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1314861348 223 NRLTDAMQGLDERSQDIIRARWLDEdnkSTLQELADRYGVSAERVRQLEKNAMKKLR 279
Cdd:cd06171     2 ERLEEALDKLPEREREVILLRFGEG---LSYEEIAEILGISRSTVRQRLHRALKKLR 55
 
Name Accession Description Interval E-value
PRK06596 PRK06596
RNA polymerase factor sigma-32; Reviewed
1-284 0e+00

RNA polymerase factor sigma-32; Reviewed


Pssm-ID: 235838 [Multi-domain]  Cd Length: 284  Bit Score: 539.76  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348   1 MTDKMQSLALAPVGNLDSYIRAANAWPMLSADEERALAEKLHYHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQ 80
Cdd:PRK06596    1 MTKALQLLALSPEGNLDAYIQAVNKIPMLTAEEEYMLAKRLREHGDLEAAKQLVLSHLRFVVHIARGYRGYGLPQADLIQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  81 EGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARE 160
Cdd:PRK06596   81 EGNIGLMKAVKRFDPEVGVRLVSFAVHWIKAEIHEYILRNWRIVKVATTKAQRKLFFNLRKAKKRLGWLNPEEVEMVAEE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 161 LGVTSKDVREMESRMAAQDMTFDLsSDDDSDSQPMAPVLYLQDKSSNFADGIEDDNWEEQAANRLTDAMQGLDERSQDII 240
Cdd:PRK06596  161 LGVSEEEVREMESRLSGQDASLDA-PIDDDDEESGAPQDYLEDKSSDPADVLEEDNWEDQRRALLADALEGLDERSRDII 239
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1314861348 241 RARWLDeDNKSTLQELADRYGVSAERVRQLEKNAMKKLRAAIEA 284
Cdd:PRK06596  240 EARWLD-DDKSTLQELAAEYGVSAERVRQIEKNAMKKLKAAIEA 282
rpoH_proteo TIGR02392
alternative sigma factor RpoH; A sigma factor is a DNA-binding protein protein that binds to ...
14-284 1.40e-167

alternative sigma factor RpoH; A sigma factor is a DNA-binding protein protein that binds to the DNA-directed RNA polymerase core to produce the holoenzyme capable of initiating transcription at specific sites. Different sigma factors act in vegetative growth, heat shock, extracytoplasmic functions (ECF), etc. This model represents the clade of sigma factors called RpoH and further restricted to the Proteobacteria. This protein may be called sigma-32, sigma factor H, heat shock sigma factor, and alternative sigma factor RpoH. Note that in some species the single locus rpoH may be replaced by two or more differentially regulated stress response sigma factors. [Cellular processes, Adaptations to atypical conditions, Transcription, Transcription factors]


Pssm-ID: 274107 [Multi-domain]  Cd Length: 270  Bit Score: 464.83  E-value: 1.40e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  14 GNLDSYIRAANAWPMLSADEERALAEKLHYHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRF 93
Cdd:TIGR02392   1 GSLDAYIRAVNRIPMLTPEEEYQLAKRLREHGDLDAAKKLVLSHLRFVVKIARGYRGYGLPQADLIQEGNIGLMKAVKRF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  94 NPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRL-GWFNQDEVEMVARELGVTSKDVREME 172
Cdd:TIGR02392  81 DPERGVRLVSFAVHWIKAEIHEYILRNWRLVKVATTKAQRKLFFNLRKMKKRLqGWLNPEEVEAIAEELGVSEREVREME 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 173 SRMAAQDMTFDLSSDDDSDSQPmAPVLYLQDKSSNFADGIEDDNWEEQAANRLTDAMQGLDERSQDIIRARWLDEDnKST 252
Cdd:TIGR02392 161 SRLSGQDMSLNASIDDDEDDGG-APIAYLVDKRSDPEDTLEEEQWEELQRQALANALGSLDARSRRIIEARWLDDD-KLT 238
                         250       260       270
                  ....*....|....*....|....*....|..
gi 1314861348 253 LQELADRYGVSAERVRQLEKNAMKKLRAAIEA 284
Cdd:TIGR02392 239 LQELAAEYGVSAERIRQIEKNAMKKLKAALAA 270
RpoD COG0568
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA ...
18-284 7.10e-109

DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440334 [Multi-domain]  Cd Length: 268  Bit Score: 315.84  E-value: 7.10e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  18 SYIRAANAWPMLSADEERALAEKLHyHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEV 97
Cdd:COG0568     1 AYLREIGRVPLLTAEEEVELARRIQ-AGDEEAKRKLVEANLRLVVSIAKKYQGRGLPLLDLIQEGNLGLMKAVEKFDPER 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  98 GVRLVSFAVHWIKAEIHEYVLRNWRIVKVATTKAQ--RKlffnLRKTKQRL--GWFNQDEVEMVARELGVTSKDVREMEs 173
Cdd:COG0568    80 GFRFSTYATWWIRQAITRAIADQWRTIRLPVHMAEtlNK----LRRAKRQLlqELGREPTPEEIAEELGVPEEKVREML- 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 174 RMAAQDMTFDlssdddsdsqpmAPVlyLQDKSSNFADGIEDDNW---EEQAANR-----LTDAMQGLDERSQDIIRARW- 244
Cdd:COG0568   155 RLAREPVSLD------------APV--GDDEDSELGDLLEDEEApspEEALEEEllreeLREALDTLTEREREILRLRFg 220
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1314861348 245 LDEDNKSTLQELADRYGVSAERVRQLEKNAMKKLRAAIEA 284
Cdd:COG0568   221 LDDGEPHTLEEIGKEFGVSRERVRQIEAKALRKLRHPLRS 260
rpoH2 PRK07500
RNA polymerase factor sigma-32; Reviewed
17-284 1.70e-66

RNA polymerase factor sigma-32; Reviewed


Pssm-ID: 236033 [Multi-domain]  Cd Length: 289  Bit Score: 209.12  E-value: 1.70e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  17 DSYIRAANAWPMLSADEERALAEKLHYHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPE 96
Cdd:PRK07500    9 RSMIRSAMKAPYLEREEEHALAYRWKDHRDEDALHRIISAHMRLVISMAGKFRRFGLPMNDLIQEGYVGLLEAAARFEPD 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  97 VGVRLVSFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRL-----GWFNQDEVEMVARELGVTSKDVREM 171
Cdd:PRK07500   89 REVRFSTYATWWIRASIQDYILRNWSIVRGGTSSAQKALFFNLRRLRARLaqadeELTKQEIHREIATALGVSLSDVEMM 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 172 ESRMAAQDMTFDlSSDDDSDSQPMAPVLYLQDKSSNFADGIEDDNWEEQAANRLTDAMQGLDERSQDIIRARWLDEDNKs 251
Cdd:PRK07500  169 DARLSGPDASLN-APQSEEDEGRSERMDFLVDDSPLPDEQVESSIDGERRRRWLTQALQTLNERELRIIRERRLREDGA- 246
                         250       260       270
                  ....*....|....*....|....*....|...
gi 1314861348 252 TLQELADRYGVSAERVRQLEKNAMKKLRAAIEA 284
Cdd:PRK07500  247 TLEALGEELGISKERVRQIEARALEKLRRALLS 279
FliA COG1191
DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA ...
45-284 7.22e-30

DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA polymerase specialized sigma subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440804 [Multi-domain]  Cd Length: 236  Bit Score: 112.61  E-value: 7.22e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  45 GDLEAAKTLILSHLRFVVHIARNYAG-YGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEI------HEYV 117
Cdd:COG1191    12 GDEEAREELIEEYLPLVKKIASRLAGrLPAELDDLIQVGLIGLIEAIDRFDPSKGVSFETYAVPRIRGAIldylrdEDWV 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 118 LRNWRIVKVATTKAQRKLFfnlrktkQRLGWFNQDEvEmVARELGVTSKDVREMESRMAAqdmtfdlssdddsdsqpmAP 197
Cdd:COG1191    92 PRSVRELARKIEEAIEELE-------QELGREPTDE-E-IAEELGISLEEVQEALEAANA------------------YQ 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 198 VLYLQDKSSN---FADGIEDDNWEEQAANR-----LTDAMQGLDERSQDIIRARWLDEDnksTLQELADRYGVSAERVRQ 269
Cdd:COG1191   145 LLSLDEPLEDgddLLDLLESGDPEEELEHEelreaLAEAIEQLPERERLVLSLYYFEEL---TLKEIAEVLGVSESRVSR 221
                         250
                  ....*....|....*
gi 1314861348 270 LEKNAMKKLRAAIEA 284
Cdd:COG1191   222 LHKKALARLREYLKE 236
PRK09210 PRK09210
RNA polymerase sigma factor RpoD; Validated
27-279 6.56e-29

RNA polymerase sigma factor RpoD; Validated


Pssm-ID: 236413 [Multi-domain]  Cd Length: 367  Bit Score: 113.16  E-value: 6.56e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  27 PMLSADEERALAEKLHyHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAV 106
Cdd:PRK09210  109 PLLTAEEEIELAKRIE-EGDEEAKQRLAEANLRLVVSIAKRYVGRGMLFLDLIQEGNMGLMKAVEKFDYRKGFKFSTYAT 187
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 107 HWIKAEIHEYV---LRNWRI-VKVATT-----KAQRKLFfnlrktkQRLGwfNQDEVEMVARELGVTSKDVREMEsRMAA 177
Cdd:PRK09210  188 WWIRQAITRAIadqARTIRIpVHMVETinkliRVQRQLL-------QELG--REPTPEEIAEEMDMPPEKVREIL-KIAQ 257
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 178 QDMTFDlssdddsdsQPMApvlylQDKSSNFADGIEDDNWE--EQAANR------LTDAMQGLDERSQDIIRARW-LDED 248
Cdd:PRK09210  258 EPVSLE---------TPIG-----EEDDSHLGDFIEDQDATspADHAAYellkeqLEDVLDTLTDREENVLRLRFgLDDG 323
                         250       260       270
                  ....*....|....*....|....*....|.
gi 1314861348 249 NKSTLQELADRYGVSAERVRQLEKNAMKKLR 279
Cdd:PRK09210  324 RTRTLEEVGKVFGVTRERIRQIEAKALRKLR 354
PRK05657 PRK05657
RNA polymerase sigma factor RpoS; Validated
27-279 1.90e-28

RNA polymerase sigma factor RpoS; Validated


Pssm-ID: 235548 [Multi-domain]  Cd Length: 325  Bit Score: 110.82  E-value: 1.90e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  27 PMLSADEERALAeKLHYHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAV 106
Cdd:PRK05657   66 PLLTAEEEVYFA-RRALRGDFAARQRMIESNLRLVVKIAKRYLNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYAT 144
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 107 HWIKAEIHEYVLRNWRIVKV---------ATTKAQRKLFFNLRKtkqrlgwfnQDEVEMVARELGVTSKDVREMES---R 174
Cdd:PRK05657  145 WWIRQTIERAIMNQTRTIRLpvhvvkelnVYLRAARELEHKLDH---------EPSAEEIAELLDKPVDDVSRMLAlneR 215
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 175 MAAQDMTFDLssdddsdsqpmapvlylqDKSSNFADGIEDDNW---EEQAANR----LTDA-MQGLDERSQDIIRARW-L 245
Cdd:PRK05657  216 ITSLDTPLGG------------------DPEKSLLDILADEQEngpEDTTQDDdmkqSIVKwLFELNDKQREVLARRFgL 277
                         250       260       270
                  ....*....|....*....|....*....|....
gi 1314861348 246 DEDNKSTLQELADRYGVSAERVRQLEKNAMKKLR 279
Cdd:PRK05657  278 LGYEAATLEDVAREIGLTRERVRQIQVEALRRLR 311
PRK07921 PRK07921
RNA polymerase sigma factor SigB; Reviewed
46-280 2.94e-25

RNA polymerase sigma factor SigB; Reviewed


Pssm-ID: 181169 [Multi-domain]  Cd Length: 324  Bit Score: 102.50  E-value: 2.94e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  46 DLEAAKT-LILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIV 124
Cdd:PRK07921   83 DGEAARRhLLEANLRLVVSLAKRYTGRGMPLLDLIQEGNLGLIRAMEKFDYTKGFKFSTYATWWIRQAITRGMADQSRTI 162
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 125 K--VATTKAQRKLFFNLRKTKQRLGwfNQDEVEMVARELGVTSKDVREM--ESR-MAAQDMtfdlssdddsdsqpmaPVl 199
Cdd:PRK07921  163 RlpVHLVEQVNKLARIKRELHQQLG--REATDEELAEESGIPEEKIADLleHSRdPVSLDM----------------PV- 223
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 200 yLQDKSSNFADGIEDDNW--EEQA--ANRLTDAMQG----LDERSQDIIRARW-LDEDNKSTLQELADRYGVSAERVRQL 270
Cdd:PRK07921  224 -GSDEEAPLGDFIEDSEAtsAENAviAGLLHTDIRSvlatLDEREQQVIRLRFgLDDGQPRTLDQIGKLFGLSRERVRQI 302
                         250
                  ....*....|
gi 1314861348 271 EKNAMKKLRA 280
Cdd:PRK07921  303 EREVMSKLRN 312
PRK08215 PRK08215
RNA polymerase sporulation sigma factor SigG;
27-283 2.29e-22

RNA polymerase sporulation sigma factor SigG;


Pssm-ID: 181296 [Multi-domain]  Cd Length: 258  Bit Score: 93.09  E-value: 2.29e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  27 PMLSADEERALAEKLHyHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAV 106
Cdd:PRK08215   17 PVLKNEEMRELFERMQ-NGDKEAREKLINGNLRLVLSVIQRFNNRGENVDDLFQVGCIGLMKAIDNFDLSQNVKFSTYAV 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 107 HWIKAEIHEYvLRNWRIVKVatTKAQRKLFFNLRKTKQRLGWFNQDE--VEMVARELGVTSKDVreMESRMAAQDmtfdl 184
Cdd:PRK08215   96 PMIIGEIRRY-LRDNNPIRV--SRSLRDIAYKALQVREKLINENSKEptVEEIAKELEVPREEV--VFALDAIQD----- 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 185 ssdddsdsqPMA---PV-------LYLQDKSSNfaDGIEDDNWEEQAAnrLTDAMQGLDERSQDIIRARWLDednKSTLQ 254
Cdd:PRK08215  166 ---------PVSlfePIyhdggdpIYVMDQISD--EKNKDENWLEEIA--LKEAMKKLNDREKLILNLRFFQ---GKTQM 229
                         250       260
                  ....*....|....*....|....*....
gi 1314861348 255 ELADRYGVSAERVRQLEKNAMKKLRAAIE 283
Cdd:PRK08215  230 EVAEEIGISQAQVSRLEKAALKHMRKYIQ 258
PRK05901 PRK05901
RNA polymerase sigma factor; Provisional
27-279 9.18e-21

RNA polymerase sigma factor; Provisional


Pssm-ID: 235640 [Multi-domain]  Cd Length: 509  Bit Score: 91.59  E-value: 9.18e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  27 PMLSADEERALA----------EKLHYHGDLEA---------------AK-TLILSHLRFVVHIARNYAGYGLPQADLIQ 80
Cdd:PRK05901  224 KLLNAEEEVELAkrieaglyaeELLAEGEKLDPelrrdlqwigrdgkrAKnHLLEANLRLVVSLAKRYTNRGLSFLDLIQ 303
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  81 EGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVK-----VAT----TKAQRKLFfnlrktkQRLGWFNQ 151
Cdd:PRK05901  304 EGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRAMADQARTIRipvhmVETinklGRIERELL-------QELGREPT 376
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 152 DEvEMvARELGVTSKDVREMesRMAAQDmtfdlssdddsdsqpmaPV-LylqDKS------SNFADGIEDDNWE--EQAA 222
Cdd:PRK05901  377 PE-EL-AKEMGFTPEKVREI--QKYNRE-----------------PIsL---DKTigkegdSQFGDFIEDSEAVspVDAV 432
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1314861348 223 NR--LTDAMQ----GLDERSQDIIRARW-LDEDNKSTLQELADRYGVSAERVRQLEKNAMKKLR 279
Cdd:PRK05901  433 SFtlLQDQLQevleTLSEREAGVIRMRFgLTDGQPKTLDEIGQVYGVTRERIRQIESKTLRKLR 496
PRK07598 PRK07598
RNA polymerase sigma factor SigC; Validated
47-279 1.90e-19

RNA polymerase sigma factor SigC; Validated


Pssm-ID: 236067 [Multi-domain]  Cd Length: 415  Bit Score: 87.23  E-value: 1.90e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  47 LEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVK- 125
Cdd:PRK07598  174 LRAKEHMIKANLRLVVSVAKKYQNRGLELLDLVQEGTLGLERAVEKFDPTKGYRFSTYAYWWIRQGITRAIATQSRTIRl 253
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 126 -VATT-------KAQRKLFFNLRKTKQrlgwfnqdeVEMVARELGVTSKDVREMESRMaaqdmtfdlssdddsdsqPMAP 197
Cdd:PRK07598  254 pVHITeklnkikKAQRKISQEKGRTPT---------IEDIAQELEMTPTQVREVLLRV------------------PRSV 306
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 198 VLYL---QDKSSNFADGIEDDN-------WEEQAANRLTDAMQGLDERSQDIIRARWLDEDNKS-TLQELADRYGVSAER 266
Cdd:PRK07598  307 SLETkvgKDKDTELGDLLETDDispeemlMRESLQRDLQHLLADLTSRERDVIRMRFGLADGHTySLAEIGRALDLSRER 386
                         250
                  ....*....|...
gi 1314861348 267 VRQLEKNAMKKLR 279
Cdd:PRK07598  387 VRQIESKALQKLR 399
PRK05572 PRK05572
RNA polymerase sporulation sigma factor, SigF/SigG family;
27-284 5.54e-18

RNA polymerase sporulation sigma factor, SigF/SigG family;


Pssm-ID: 180137 [Multi-domain]  Cd Length: 252  Bit Score: 81.17  E-value: 5.54e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  27 PMLSADEERALAEKLHyHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAV 106
Cdd:PRK05572   12 PQLKDEENKELIKKSQ-DGDQEARDTLVEKNLRLVWSVVQRFLNRGYEPDDLFQIGCIGLLKAVDKFDLSYDVKFSTYAV 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 107 HWIKAEIHEYvLRNWRIVKVatTKAQRKLFFNLRKTKQRLG-WFNQD-EVEMVARELGVTSKDVremesrMAAQDMTFDL 184
Cdd:PRK05572   91 PMIIGEIQRF-LRDDGTVKV--SRSLKETANKIRKDKDELSkELGREpTIEELAEYLGVTPEEV------VLAQEASRSP 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 185 SSDDDSDSQPMAPVLYLQDKssnFADGIEDDnWEEQAAnrLTDAMQGLDERSQDIIRARWLDEDNKStlqELADRYGVSA 264
Cdd:PRK05572  162 QSIHETVHENDGDPITLLDQ---IADQSEED-WFDKIA--LKEAIRELDERERLIVYLRYFKDKTQS---EVAKRLGISQ 232
                         250       260
                  ....*....|....*....|
gi 1314861348 265 ERVRQLEKNAMKKLRAAIEA 284
Cdd:PRK05572  233 VQVSRLEKKILKQMKEKLDE 252
PRK05803 PRK05803
RNA polymerase sporulation sigma factor SigK;
15-278 9.68e-18

RNA polymerase sporulation sigma factor SigK;


Pssm-ID: 180266 [Multi-domain]  Cd Length: 233  Bit Score: 79.99  E-value: 9.68e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  15 NLDSYIrAANAWPM-LSADEERALAEKLHyHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRF 93
Cdd:PRK05803   17 FLVSYV-KNNSFPQpLSEEEERKYLELMK-EGDEEARNILIERNLRLVAHIVKKFENTGEDVDDLISIGTIGLIKAIESF 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  94 NPEVGVRLVSFAVHWIKAEIheyvLRNWRivkvattkaqrklffNLRKTKQRLgwFNQDevemvarELGVtSKDVREMEs 173
Cdd:PRK05803   95 DAGKGTKLATYAARCIENEI----LMHLR---------------NLKKTKKEV--SLQD-------PIGV-DKEGNEIS- 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 174 rmaaqdmtfdlssdddsdsqpmapvlyLQDKSSNFADGIEDDNWEEQAANRLTDAMQGLDERSQDIIRARW-LDEDNKST 252
Cdd:PRK05803  145 ---------------------------LIDILGSEEDDVIEQVELKMEVEKLYKKIDILDEREKEVIEMRYgLGNGKEKT 197
                         250       260
                  ....*....|....*....|....*.
gi 1314861348 253 LQELADRYGVSAERVRQLEKNAMKKL 278
Cdd:PRK05803  198 QREIAKALGISRSYVSRIEKRALKKL 223
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
53-123 3.88e-17

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 74.16  E-value: 3.88e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1314861348  53 LILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRI 123
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERGVSFSTWLYTIIRNAIIDYLRKQRRT 71
PRK07405 PRK07405
RNA polymerase sigma factor SigD; Validated
48-279 6.29e-17

RNA polymerase sigma factor SigD; Validated


Pssm-ID: 180963 [Multi-domain]  Cd Length: 317  Bit Score: 79.03  E-value: 6.29e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  48 EAAK-TLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVKV 126
Cdd:PRK07405   80 EAAKrKMVEANLRLVVSVAKKYLKRNVDLLDLIQEGTIGMQRGVEKFDPTKGYRFSTYAYWWIRQAITRAIAEKSRTIRL 159
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 127 ---------ATTKAQRKLffnlrktKQRLGwfNQDEVEMVARELGVTSKDVREMESRmAAQDMTFDLSSDddsdsqpmap 197
Cdd:PRK07405  160 pihiteklnKIKKAQRQL-------SQQLG--RAATIGELAEELELTPKQVREYLER-ARQPLSLDLRVG---------- 219
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 198 vlylQDKSSNFADGIEDD-----NWEEQAANR--LTDAMQGLDERSQDIIRARW-LDEDNKSTLQELADRYGVSAERVRQ 269
Cdd:PRK07405  220 ----DNQDTELGELLEDTgaspeDFATQSSLQldLERLMEDLTPQQKEVIALRFgLEDGQPLTLAKIGERLNISRERVRQ 295
                         250
                  ....*....|
gi 1314861348 270 LEKNAMKKLR 279
Cdd:PRK07405  296 IEREALSKLR 305
PRK05949 PRK05949
RNA polymerase sigma factor; Validated
49-279 3.08e-16

RNA polymerase sigma factor; Validated


Pssm-ID: 180321 [Multi-domain]  Cd Length: 327  Bit Score: 77.19  E-value: 3.08e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  49 AAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVK--V 126
Cdd:PRK05949   92 AKQKMIEANLRLVVAIAKKYQKRNMEFLDLIQEGTLGLERGVEKFDPTRGYKFSTYAYWWIRQAITRAIAQQARTIRlpI 171
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 127 ATTKAQRKLFFNLRKTKQRLGwfNQDEVEMVARELGVTSKDVREMESrMAAQDMTFDLssdDDSDSQPMAPVLYLQDkss 206
Cdd:PRK05949  172 HITEKLNKIKKTQRELSQKLG--RSATPAEIAKELELEPSQIREYLS-MARQPISLDV---RVGDNQDTELSELLED--- 242
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1314861348 207 nfaDGIEDDNWEEQAANR--LTDAMQGLDERSQDIIRARWLDEDNKS-TLQELADRYGVSAERVRQLEKNAMKKLR 279
Cdd:PRK05949  243 ---EGPSPDQYITQELLRqdLNNLLAELTPQQREVLTLRFGLEDGKElSLAKVGERLNLSRERVRQLEHQALAHLR 315
PRK08301 PRK08301
RNA polymerase sporulation sigma factor SigE;
27-123 3.08e-16

RNA polymerase sporulation sigma factor SigE;


Pssm-ID: 236228 [Multi-domain]  Cd Length: 234  Bit Score: 76.05  E-value: 3.08e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  27 PMLSADEERALAEKLHyHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAV 106
Cdd:PRK08301   32 PPLSKEEEEYLLNKLP-KGDEAVRSLLIERNLRLVVYIARKFENTGINIEDLISIGTIGLIKAVNTFNPEKKIKLATYAS 110
                          90
                  ....*....|....*..
gi 1314861348 107 HWIKAEIHEYVLRNWRI 123
Cdd:PRK08301  111 RCIENEILMYLRRNNKV 127
PRK07406 PRK07406
RNA polymerase sigma factor RpoD; Validated
49-279 3.25e-16

RNA polymerase sigma factor RpoD; Validated


Pssm-ID: 236012 [Multi-domain]  Cd Length: 373  Bit Score: 77.52  E-value: 3.25e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  49 AAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVkvat 128
Cdd:PRK07406  137 AKEKMVQSNLRLVVSIAKKYMNRGLSFQDLIQEGSLGLIRAAEKFDHEKGYKFSTYATWWIRQAITRAIADQSRTI---- 212
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 129 tkaqrKLFFNLRKTKQRLgwfnQDEVEMVARELGVTSKDvREMESRMaaqDMTFDLSSDDDSDSQ-PMA---PVLYLQDk 204
Cdd:PRK07406  213 -----RLPVHLYETISRI----KKTTKVLSQEFGRKPTE-EEIAESM---EMTIEKLRFIAKSAQlPISletPIGKEED- 278
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 205 sSNFADGIEDD--NWEEQAANR-----LTDAMQGLDERSQDIIRARW-LDEDNKSTLQELADRYGVSAERVRQLEKNAMK 276
Cdd:PRK07406  279 -SRLGDFIEADgeTPEDDVAKNllredLEGVLATLSPRERDVLRLRYgLDDGRMKTLEEIGQIFNVTRERIRQIEAKALR 357

                  ...
gi 1314861348 277 KLR 279
Cdd:PRK07406  358 KLR 360
PRK08583 PRK08583
RNA polymerase sigma factor SigB; Validated
29-282 1.88e-15

RNA polymerase sigma factor SigB; Validated


Pssm-ID: 236306 [Multi-domain]  Cd Length: 257  Bit Score: 73.96  E-value: 1.88e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  29 LSADEERALAEKLHYHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAVHW 108
Cdd:PRK08583   10 LTKEEVNKWIAEYQENQDEEAQEKLVKHYKNLVESLAYKYSKGQSHHEDLVQVGMVGLLGAIRRYDPSFGRSFEAFAVPT 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 109 IKAEIHEYvLRN--W-------------RIVKVA---TTKAQRklffnlrktkqrlgwfnQDEVEMVARELGVTSKDVRE 170
Cdd:PRK08583   90 IIGEIKRY-LRDktWsvhvprrikelgpKIKKAVdelTTELQR-----------------SPKISEIADRLGVSEEEVLE 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 171 -MESRMAAQDMTFDlssdddsdsqpmAPVLYLQDKSS-NFAD--GIEDDNWEEqaANR---LTDAMQGLDERSQDIIRAR 243
Cdd:PRK08583  152 aMEMGKSYQALSVD------------HSIEADSDGSTvTLLDivGQQEDGYEL--TEQrmiLEKILPVLSDREKSIIQCT 217
                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1314861348 244 WLdeDNKSTlQELADRYGVSAERVRQLEKNAMKKLRAAI 282
Cdd:PRK08583  218 FI--ENLSQ-KETGERLGISQMHVSRLQRQAIKKLREAA 253
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
48-282 4.66e-14

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 68.14  E-value: 4.66e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  48 EAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVgvRLVSFAVHWIKAEIHEYvlrnwrivkva 127
Cdd:TIGR02937   1 EAFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDPEG--SFKAWLFRIARNLILDY----------- 67
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 128 ttkaqrklffnLRKTKQRLGWFNQDEVEmvarelgvtskdvremesrmaaqdmtfdlssdddsdsqpmapvlylqdksSN 207
Cdd:TIGR02937  68 -----------LRRKRRLRRELDLLEEL--------------------------------------------------LD 86
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1314861348 208 FADGIEDDNWEEQAANRLTDAMQGLDERSQDIIRARWLDEdnkSTLQELADRYGVSAERVRQLEKNAMKKLRAAI 282
Cdd:TIGR02937  87 SDPSPEEELEQEEEREALREALEKLPEREREVLVLRYLEG---LSYKEIAEILGISVGTVKRRLKRARKKLRELL 158
Sigma70_r4 pfam04545
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
228-280 1.49e-12

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives.


Pssm-ID: 461347 [Multi-domain]  Cd Length: 50  Bit Score: 60.90  E-value: 1.49e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1314861348 228 AMQGLDERSQDIIRARWLDEdnkSTLQELADRYGVSAERVRQLEKNAMKKLRA 280
Cdd:pfam04545   1 ALASLPPRERQVLVLRYGEG---LTLEEIGERLGISRERVRQIEKRALRKLRK 50
PRK07408 PRK07408
RNA polymerase sigma factor SigF; Reviewed
77-278 1.82e-12

RNA polymerase sigma factor SigF; Reviewed


Pssm-ID: 180965 [Multi-domain]  Cd Length: 256  Bit Score: 65.71  E-value: 1.82e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  77 DLIQEGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEY---------VLRNWRIVKVATTKAQRKLffnlrktKQRLG 147
Cdd:PRK07408   55 DLVQVGSLGLIRAIERFDPSKGHAFSSFAIPYIRGEIQHYlrdksptvrIPRRWQELQRQAKKVRQEL-------RQELG 127
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 148 wfNQDEVEMVARELGVTSKDVREMesRMAAQDMTfdlssdddsdsqPM---APVLYLQDKSSNFADGIEDDNWEEQAAN- 223
Cdd:PRK07408  128 --RQPTDQEIAQALDISLEEWQEI--KLALQNRT------------PLsldAPVNQDEDGSTSLGDLLPDPRYRSFQLAq 191
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1314861348 224 ----RLTDAMQGLDERSQDIIRARWLDEdnkSTLQELADRYGVSAERV-RQLEK--NAMKKL 278
Cdd:PRK07408  192 edriRLQQALAQLEERTREVLEFVFLHD---LTQKEAAERLGISPVTVsRRVKKglDQLKKL 250
PRK07122 PRK07122
RNA polymerase sigma factor SigF; Reviewed
63-283 3.59e-12

RNA polymerase sigma factor SigF; Reviewed


Pssm-ID: 168831 [Multi-domain]  Cd Length: 264  Bit Score: 64.80  E-value: 3.59e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  63 HIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVKVAttKAQRKLFFNLRKT 142
Cdd:PRK07122   55 HIARRFDGRGEPRDDLVQVARVGLVNAVNRFDVETGSDFVSFAVPTIMGEVRRHFRDNSWSVKVP--RRLKELHLRLGRA 132
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 143 ----KQRLGwfNQDEVEMVARELGVTSKDVRE-MESRMAAQDMTFDlssdddsdsqpmAPVLYLQDKSSNFADGIED-DN 216
Cdd:PRK07122  133 taelSQRLG--RAPTASELAAELGMDREEVVEgLVAGSAYNTLSID------------SGGGSGDDDARAIADTLGDvDA 198
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1314861348 217 WEEQAANR--LTDAMQGLDERSQDIIRARWLDednKSTLQELADRYGVSAERVRQLEKNAMKKLRAAIE 283
Cdd:PRK07122  199 GLDQIENReaLRPLLAALPERERTVLVLRFFE---SMTQTQIAERVGISQMHVSRLLAKTLARLRDQLE 264
PRK05658 PRK05658
RNA polymerase sigma factor RpoD; Validated
48-93 5.98e-11

RNA polymerase sigma factor RpoD; Validated


Pssm-ID: 235549 [Multi-domain]  Cd Length: 619  Bit Score: 62.50  E-value: 5.98e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1314861348  48 EAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRF 93
Cdd:PRK05658  380 RAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKF 425
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
223-279 1.97e-10

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 55.19  E-value: 1.97e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1314861348 223 NRLTDAMQGLDERSQDIIRARWLDEdnkSTLQELADRYGVSAERVRQLEKNAMKKLR 279
Cdd:cd06171     2 ERLEEALDKLPEREREVILLRFGEG---LSYEEIAEILGISRSTVRQRLHRALKKLR 55
PRK05911 PRK05911
RNA polymerase sigma factor sigma-28; Reviewed
46-284 3.69e-10

RNA polymerase sigma factor sigma-28; Reviewed


Pssm-ID: 235644 [Multi-domain]  Cd Length: 257  Bit Score: 59.25  E-value: 3.69e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  46 DLEAAKTLILSHLRFVVHIARNYAGyGLPQ----ADLIQEGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYvLRNW 121
Cdd:PRK05911   21 EIEYRDVLIEFYLPLVKNVAHRLIS-GMPShvktEDLYASGVEGLVRAVERFDPEKSRRFEGYALFLIKAAIIDD-LRKQ 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 122 RIVKVATTKAQRKLFFNLRKTKQRLGwfnqdevemvaRElgVTSKDVREMeSRMAAQDMTfdlssDDDSDSQPmAPVLYL 201
Cdd:PRK05911   99 DWVPRSVHQKANKLADAMDSLRQSLG-----------KE--PTDGELCEY-LNISQQELS-----GWFSSARP-ALILSL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 202 QDKSSNFADG---------IEDDNWE--------EQAANRLTDAMQGLDERSQDIIRARWLDEdnkSTLQELADRYGVSA 264
Cdd:PRK05911  159 NEEFPCQSDDeaglaleerIADERAEtgydvvdkKEFSSILAEAILALEEKERKVMALYYYEE---LVLKEIGKILGVSE 235
                         250       260
                  ....*....|....*....|
gi 1314861348 265 ERVRQLEKNAMKKLRAAIEA 284
Cdd:PRK05911  236 SRVSQIHSKALLKLRATLSA 255
fliA PRK06986
flagellar biosynthesis sigma factor; Validated
51-280 4.69e-10

flagellar biosynthesis sigma factor; Validated


Pssm-ID: 235901 [Multi-domain]  Cd Length: 236  Bit Score: 58.32  E-value: 4.69e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  51 KTLILSHLRFVVHIARNYAGYgLPQA----DLIQEGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRN-W--RI 123
Cdd:PRK06986   11 DELVEQYAPLVKRIALRLKAR-LPASvdldDLIQAGMIGLLEAARRYDGEQGASFETYAGQRIRGAMLDELRSLdWvpRS 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 124 VKvattKAQRKLFFNLRKTKQRLGwFNQDEVEmVARELGVTSKDVREM-----ESRMAAQDmtfDLSSDDDSDSQPMApv 198
Cdd:PRK06986   90 VR----RNAREVAQAIRQLEQELG-REPTDTE-VAEKLGLSLEEYREMlldtnISQLFSID---ELRGEHGDSILVTE-- 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 199 lylQDKSSNFADGIEDDNWEEqaanRLTDAMQGLDERSQDIIRARWLDEDNkstLQELADRYGVSAERVRQLEKNAMKKL 278
Cdd:PRK06986  159 ---DHQDEDPLQQLEDEELRE----ALVEAIESLPEREQLVLSLYYQEELN---LKEIGAVLGVSESRVSQIHSQAIKRL 228

                  ..
gi 1314861348 279 RA 280
Cdd:PRK06986  229 RA 230
PRK06288 PRK06288
RNA polymerase sigma factor WhiG; Reviewed
32-280 1.17e-07

RNA polymerase sigma factor WhiG; Reviewed


Pssm-ID: 235770 [Multi-domain]  Cd Length: 268  Bit Score: 51.61  E-value: 1.17e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  32 DEERALAEKLHYHGDLEAAKTLILSHLRFVVHIArNYAGYGLP----QADLIQEGNIGLMKAVRRFNPEVGVRLVSFAVH 107
Cdd:PRK06288   15 QDETELWREYKKTGDPKIREYLILKYSPLVKYVA-GRIAVGMPqnveFDDLVSYGVFGLIDAIEKFDPEREIKFKTYAVT 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 108 WIKAEIHEYvLR--NW--RIVKVATTKAQRKLFFnlrkTKQRLGWfNQDEVEmVARELGVTSKDVREMESRMAAQDMTfd 183
Cdd:PRK06288   94 RIRGAIFDE-LRsiDWipRSVRQKARQIERAIAM----LEARLGR-TPSDEE-IADELGISLEEYNSLLSKLSGTSVV-- 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 184 lssdddsdsqPMAPVLYLQDKSSNFA--DGIED---DNWE-----EQAANRLTDAMQGLDERSQDIIRARWLDEdnkSTL 253
Cdd:PRK06288  165 ----------SLNDLWFGGDEGDEVSlmDTLESpaaLNPDeiaerEEIKRVIVEAIKTLPEREKKVLILYYYED---LTL 231
                         250       260
                  ....*....|....*....|....*..
gi 1314861348 254 QELADRYGVSAERVRQLEKNAMKKLRA 280
Cdd:PRK06288  232 KEIGKVLGVTESRISQLHTKAVLQLRA 258
PRK08295 PRK08295
RNA polymerase sporulation sigma factor SigH;
45-104 8.20e-07

RNA polymerase sporulation sigma factor SigH;


Pssm-ID: 181361 [Multi-domain]  Cd Length: 208  Bit Score: 48.75  E-value: 8.20e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  45 GDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEvgvRLVSF 104
Cdd:PRK08295   21 GDKEALEYLIEKYKNFVRAKARSYFLIGADREDIVQEGMIGLYKAIRDYDKD---KLSSF 77
PRK07670 PRK07670
FliA/WhiG family RNA polymerase sigma factor;
33-283 7.29e-05

FliA/WhiG family RNA polymerase sigma factor;


Pssm-ID: 181075 [Multi-domain]  Cd Length: 251  Bit Score: 43.11  E-value: 7.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  33 EERALAEKLHYHGDLEAAKTLILSHLRFV-VHIARNYAGygLPQA----DLIQEGNIGLMKAVRRFNPEVGVRLVSFAVH 107
Cdd:PRK07670    7 EEQKLWDRWKEERDPDAADELIRRYMPLVhYHVQRISVG--LPKSvskdDLKSLGMLGLYDALEKFDPSRDLKFDTYASF 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 108 WIKAEIHEYVLRNWRIVKVATTKAqRKLFFNLRKTKQRLGwfNQDEVEMVARELGVTSKDV-REMESRMAAQDMTFDlss 186
Cdd:PRK07670   85 RIRGAIIDGLRKEDWLPRSMREKT-KKVEAAIEKLEQRYM--RNVTPKEVAAELGMTEEEVeATMNEGFFANLLSID--- 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 187 dddsdsqpmaPVLYLQDKSSNFADGIEDDNW---EEQAANR-----LTDAMQGLDERSQDIIRARWLDEdnkSTLQELAD 258
Cdd:PRK07670  159 ----------EKTHDQDDGENVSVTIRDDKTptpEEKLLKEelieeLAEKIKQLSEKEQLVISLFYKEE---LTLTEIGQ 225
                         250       260
                  ....*....|....*....|....*
gi 1314861348 259 RYGVSAERVRQLEKNAMKKLRAAIE 283
Cdd:PRK07670  226 VLNLSTSRISQIHSKALFKLKKLLE 250
PRK12427 PRK12427
FliA/WhiG family RNA polymerase sigma factor;
77-279 2.00e-03

FliA/WhiG family RNA polymerase sigma factor;


Pssm-ID: 183523 [Multi-domain]  Cd Length: 231  Bit Score: 38.69  E-value: 2.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348  77 DLIQEGNIGLMKAVRRFN-PEVGvrLVSFAVHWIKAEI-HEYVLRNWRIVKVATTKAQRKLFfnLRKTKQRLGwfNQDEV 154
Cdd:PRK12427   47 DMEQIALMGLLEALRRYGhPDEQ--FAAYAVHRIRGAIlDELRELDWRPRRLRQKTHKTNDA--IREIAKRLG--HEPNF 120
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348 155 EMVARELGVTSKDVREMESRMAAQDMtfdlssdddsdsQPMAPVLYLQdkssNFADGIEDDNWEEQAANR--LTDAMQGL 232
Cdd:PRK12427  121 EEISAELNLTAEEYQEYLLLENAGTL------------ESLDELLALE----AHNDILQSRDLEENIIIEdnLKQALSQL 184
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1314861348 233 DERSQDIIRARWLDEDNkstLQELADRYGVSAERVRQLEKNAMKKLR 279
Cdd:PRK12427  185 DEREQLILHLYYQHEMS---LKEIALVLDLTEARICQLNKKIAQKIK 228
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
209-284 2.35e-03

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 38.05  E-value: 2.35e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1314861348 209 ADGIEDDNWEEQAANRLTDAMQGLDERSQDIIRARWLDEDnksTLQELADRYGVSAERVRQLEKNAMKKLRAAIEA 284
Cdd:COG1595   105 AADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGL---SYAEIAEILGISEGTVKSRLSRARKKLREALEE 177
TelA pfam05816
Toxic anion resistance protein (TelA); This family consists of several prokaryotic TelA like ...
1-92 4.85e-03

Toxic anion resistance protein (TelA); This family consists of several prokaryotic TelA like proteins. TelA and KlA are associated with tellurite resistance and plasmid fertility inhibition.


Pssm-ID: 461748  Cd Length: 330  Bit Score: 37.88  E-value: 4.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1314861348   1 MTDKMQSLALAPVGNLDSYIRAANA-WPMLSADEERALAEKLHYHGDLEAAKTL-----ILSHLRFVVH---IARNYAGY 71
Cdd:pfam05816 117 MLDQMYEKNLEYFKELEKYIAAGELkLEELDAELLPELEAKAAASGDPEDAQALrdlrqALFRLEQRIHdleLQRAVSIQ 196
                          90       100
                  ....*....|....*....|.
gi 1314861348  72 GLPQADLIQEGNIGLMKAVRR 92
Cdd:pfam05816 197 TAPQIRLVQNNNQELIEKIQS 217
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH