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Conserved domains on  [gi|1347481391|gb|AVG75632|]
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acyl carrier protein [Pantoea ananatis]

Protein Classification

acyl carrier protein( domain architecture ID 10012344)

acyl carrier protein functions as the carrier of the growing fatty acid chain in fatty acid biosynthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK05350 PRK05350
acyl carrier protein; Provisional
 1-82 3.49e-43

acyl carrier protein; Provisional


:

Pssm-ID: 180033  Cd Length: 82  Bit Score: 134.35  E-value: 3.49e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347481391  1 MTEQNAIYEEVTALLVKLFEIDPQDISPQARLYEDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQDVVDAVERLL 80
Cdd:PRK05350   1 MMTREEILERLRAILVELFEIDPEDITPEANLYEDLDLDSIDAVDLVVHLQKLTGKKIKPEEFKSVRTVQDVVDAVERLL 80


                 ..
gi 1347481391 81 KE 82
Cdd:PRK05350  81 KE 82
 
Name Accession Description Interval E-value
PRK05350 PRK05350
acyl carrier protein; Provisional
 1-82 3.49e-43

acyl carrier protein; Provisional


Pssm-ID: 180033  Cd Length: 82  Bit Score: 134.35  E-value: 3.49e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347481391  1 MTEQNAIYEEVTALLVKLFEIDPQDISPQARLYEDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQDVVDAVERLL 80
Cdd:PRK05350   1 MMTREEILERLRAILVELFEIDPEDITPEANLYEDLDLDSIDAVDLVVHLQKLTGKKIKPEEFKSVRTVQDVVDAVERLL 80


                 ..
gi 1347481391 81 KE 82
Cdd:PRK05350  81 KE 82
AcpP COG0236
Acyl carrier protein [Lipid transport and metabolism]; Acyl carrier protein is part of the ...
 4-81 4.00e-17

Acyl carrier protein [Lipid transport and metabolism]; Acyl carrier protein is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440006 [Multi-domain]  Cd Length: 80  Bit Score: 68.73  E-value: 4.00e-17
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1347481391  4 QNAIYEEVTALLVKLFEIDPQDISPQARLYEDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQDVVDAVERLLK 81
Cdd:COG0236    3 REELEERLAEIIAEVLGVDPEEITPDDSFFEDLGLDSLDAVELIAALEEEFGIELPDTELFEYPTVADLADYLEEKLA 80
PP-binding pfam00550
Phosphopantetheine attachment site; A 4'-phosphopantetheine prosthetic group is attached ...
 9-71 3.23e-09

Phosphopantetheine attachment site; A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes members not included in Prosite. The inclusion of these members is supported by sequence analysis and functional evidence. The related domain of Swiss:P19828 has the attachment serine replaced by an alanine.


Pssm-ID: 425746 [Multi-domain]  Cd Length: 62  Bit Score: 47.94  E-value: 3.23e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1347481391  9 EEVTALLVKLFEIDPQDISPQARLYeDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQD 71
Cdd:pfam00550  1 ERLRELLAEVLGVPAEEIDPDTDLF-DLGLDSLLAVELIARLEEEFGVEIPPSDLFEHPTLAE 62
acyl_carrier TIGR00517
acyl carrier protein; This small protein has phosphopantetheine covalently bound to a Ser ...
 6-77 1.60e-08

acyl carrier protein; This small protein has phosphopantetheine covalently bound to a Ser residue. It acts as a carrier of the growing fatty acid chain, which is bound to the prosthetic group, during fatty acid biosynthesis. Homologous phosphopantetheine-binding domains are found in longer proteins. Acyl carrier proteins scoring above the noise cutoff but below the trusted cutoff may be specialized versions. These include those involved in mycolic acid biosynthesis in the Mycobacteria, lipid A biosynthesis in Rhizobium, actinorhodin polyketide synthesis in Streptomyces coelicolor, etc. This protein is not found in the Archaea.Gene name acpP.S (Ser) at position 37 in the seed alignment, in the motif DSLD, is the phosphopantetheine attachment site. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 213536 [Multi-domain]  Cd Length: 77  Bit Score: 46.62  E-value: 1.60e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1347481391  6 AIYEEVTALLVKLFEIDPQDISPQARLYEDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQDVVDAVE 77
Cdd:TIGR00517  3 EIFEKVKAIIKEQLNVDEDQITTDARFVEDLGADSLDTVELVMALEEEFDIEIPDEEAEKIATVGDAVNYIE 74
 
Name Accession Description Interval E-value
PRK05350 PRK05350
acyl carrier protein; Provisional
 1-82 3.49e-43

acyl carrier protein; Provisional


Pssm-ID: 180033  Cd Length: 82  Bit Score: 134.35  E-value: 3.49e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347481391  1 MTEQNAIYEEVTALLVKLFEIDPQDISPQARLYEDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQDVVDAVERLL 80
Cdd:PRK05350   1 MMTREEILERLRAILVELFEIDPEDITPEANLYEDLDLDSIDAVDLVVHLQKLTGKKIKPEEFKSVRTVQDVVDAVERLL 80


                 ..
gi 1347481391 81 KE 82
Cdd:PRK05350  81 KE 82
AcpP COG0236
Acyl carrier protein [Lipid transport and metabolism]; Acyl carrier protein is part of the ...
 4-81 4.00e-17

Acyl carrier protein [Lipid transport and metabolism]; Acyl carrier protein is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440006 [Multi-domain]  Cd Length: 80  Bit Score: 68.73  E-value: 4.00e-17
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1347481391  4 QNAIYEEVTALLVKLFEIDPQDISPQARLYEDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQDVVDAVERLLK 81
Cdd:COG0236    3 REELEERLAEIIAEVLGVDPEEITPDDSFFEDLGLDSLDAVELIAALEEEFGIELPDTELFEYPTVADLADYLEEKLA 80
PP-binding pfam00550
Phosphopantetheine attachment site; A 4'-phosphopantetheine prosthetic group is attached ...
 9-71 3.23e-09

Phosphopantetheine attachment site; A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the attachment of activated fatty acid and amino-acid groups. This domain forms a four helix bundle. This family includes members not included in Prosite. The inclusion of these members is supported by sequence analysis and functional evidence. The related domain of Swiss:P19828 has the attachment serine replaced by an alanine.


Pssm-ID: 425746 [Multi-domain]  Cd Length: 62  Bit Score: 47.94  E-value: 3.23e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1347481391  9 EEVTALLVKLFEIDPQDISPQARLYeDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQD 71
Cdd:pfam00550  1 ERLRELLAEVLGVPAEEIDPDTDLF-DLGLDSLLAVELIARLEEEFGVEIPPSDLFEHPTLAE 62
acpP PRK00982
acyl carrier protein; Provisional
 4-81 5.33e-09

acyl carrier protein; Provisional


Pssm-ID: 179197 [Multi-domain]  Cd Length: 78  Bit Score: 47.86  E-value: 5.33e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1347481391  4 QNAIYEEVTALLVKLFEIDPQDISPQARLYEDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQDVVDAVERLLK 81
Cdd:PRK00982   1 MSEIFEKVKKIIVEQLGVDEEEVTPEASFVDDLGADSLDTVELVMALEEEFGIEIPDEDAEKIKTVGDAVDYIEKHQK 78
acyl_carrier TIGR00517
acyl carrier protein; This small protein has phosphopantetheine covalently bound to a Ser ...
 6-77 1.60e-08

acyl carrier protein; This small protein has phosphopantetheine covalently bound to a Ser residue. It acts as a carrier of the growing fatty acid chain, which is bound to the prosthetic group, during fatty acid biosynthesis. Homologous phosphopantetheine-binding domains are found in longer proteins. Acyl carrier proteins scoring above the noise cutoff but below the trusted cutoff may be specialized versions. These include those involved in mycolic acid biosynthesis in the Mycobacteria, lipid A biosynthesis in Rhizobium, actinorhodin polyketide synthesis in Streptomyces coelicolor, etc. This protein is not found in the Archaea.Gene name acpP.S (Ser) at position 37 in the seed alignment, in the motif DSLD, is the phosphopantetheine attachment site. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 213536 [Multi-domain]  Cd Length: 77  Bit Score: 46.62  E-value: 1.60e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1347481391  6 AIYEEVTALLVKLFEIDPQDISPQARLYEDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQDVVDAVE 77
Cdd:TIGR00517  3 EIFEKVKAIIKEQLNVDEDQITTDARFVEDLGADSLDTVELVMALEEEFDIEIPDEEAEKIATVGDAVNYIE 74
PTZ00171 PTZ00171
acyl carrier protein; Provisional
 11-81 7.67e-06

acyl carrier protein; Provisional


Pssm-ID: 240304  Cd Length: 148  Bit Score: 41.22  E-value: 7.67e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1347481391  11 VTALLVKLFEIDPQDISPQARLYEDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQDVVDAVERLLK 81
Cdd:PTZ00171   75 VKKVVKNFEKVDASKITPESNFVKDLGADSLDVVELLIAIEQEFNLTIPDHDAEKIKTVQDAIDYIEQNNM 145
PRK08172 PRK08172
acyl carrier protein;
21-81 8.62e-06

acyl carrier protein;


Pssm-ID: 181266  Cd Length: 82  Bit Score: 39.87  E-value: 8.62e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1347481391 21 IDPQDISPQARLYEDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQDVVDAVERLLK 81
Cdd:PRK08172  19 VDVDSINGQTHLVEDLYADSLDLIDIVFGLSEEFDISCNENDLPDMTTFADICRVVKKSLE 79
PRK09184 PRK09184
acyl carrier protein; Provisional
 1-55 5.39e-05

acyl carrier protein; Provisional


Pssm-ID: 181682  Cd Length: 89  Bit Score: 37.72  E-value: 5.39e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 1347481391  1 MTEQNAIYEEVTALLV---KLFEIDPQDISPQARLY-EDLELDSIDAVDMIVHLQKKTG 55
Cdd:PRK09184   1 MSSMTALERELAELIVeelNLEDVQPESIDADAPLYgEGLGLDSIDILEIALVISKRYG 59
acpP CHL00124
acyl carrier protein; Validated
 1-78 5.22e-04

acyl carrier protein; Validated


Pssm-ID: 177047 [Multi-domain]  Cd Length: 82  Bit Score: 35.00  E-value: 5.22e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1347481391  1 MTEQNaIYEEVTALLVKLFEIDPQDISPQARLYEDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQDVVDAVER 78
Cdd:CHL00124   1 MTKND-IFEKVQSIVAEQLGIEKSEVTLDANFTRDLGADSLDVVELVMAIEEKFDIEIPDEDAEKISTLQEAVDFISQ 77
PRK12449 PRK12449
acyl carrier protein; Provisional
 1-81 1.14e-03

acyl carrier protein; Provisional


Pssm-ID: 183533 [Multi-domain]  Cd Length: 80  Bit Score: 34.29  E-value: 1.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1347481391  1 MTEQnAIYEEVTALLVKLFEIDPQDISPQARLYEDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQDVVDAVERLL 80
Cdd:PRK12449   1 MTRE-EIFERLINLIQKQRSYLSLAITEQTHLKDDLAVDSIELVEFIINVEDEFHIAIPDEDVEDMVSMGDLLDYLVQRL 79


                 .
gi 1347481391 81 K 81
Cdd:PRK12449  80 T 80
PRK06508 PRK06508
acyl carrier protein; Provisional
 6-63 1.41e-03

acyl carrier protein; Provisional


Pssm-ID: 180597  Cd Length: 93  Bit Score: 34.41  E-value: 1.41e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 1347481391  6 AIYEEVTALLVKLFEIDPQDISPQARLYEDLELDSIDAVDMIVHLQKKTGKKIKPEEF 63
Cdd:PRK06508   3 STFDKVADIIAETSDIPRDTITPESHTIDDLGIDSLDFLDIVFAIDKAFGIKLPLEQW 60
PRK05883 PRK05883
acyl carrier protein; Validated
 5-76 9.92e-03

acyl carrier protein; Validated


Pssm-ID: 180304  Cd Length: 91  Bit Score: 32.12  E-value: 9.92e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1347481391  5 NAIYEEVTALLVKLFEIDPQDISPQARLYEDLELDSID-AVDMiVHLQKKTGKKIKPEEFKAVRTVQDVVDAV 76
Cdd:PRK05883  13 STVSATLLSILRDDLNVDLTRVTPDARLVDDVGLDSVAfAVGM-VAIEERLGVALSEEDLLSCDTVGDLEAAI 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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