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Conserved domains on  [gi|1352182024|gb|AVI53040|]
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knotted carbamoyltransferase YgeW [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

knotted carbamoyltransferase YgeW( domain architecture ID 11482624)

knotted carbamoyltransferase YgeW is a putative carbamoyltransferase, but no activity can be detected with allantoin or 25 other related compounds, including 20 naturally occurring amino acids, N-acetyl-L-ornithine, N-succinyl-L-ornithine, L-ornithine, oxamate, beta-alanine and putrescine

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK07200 PRK07200
aspartate/ornithine carbamoyltransferase family protein; Validated
2-396 0e+00

aspartate/ornithine carbamoyltransferase family protein; Validated


:

Pssm-ID: 235961 [Multi-domain]  Cd Length: 395  Bit Score: 862.89  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024   2 MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASA 81
Cdd:PRK07200    1 MKTVNELIKDLNSLTSHMHEKDFLLTWEKTPDELKAVLDVADALRALREENISTKVFNSGLGISVFRDNSTRTRFSYASA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  82 LNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQC 161
Cdd:PRK07200   81 CNLLGLEVQDLDEGKSQIAHGETVRETANMISFMADVIGIRDDMYIGKGNAYMREVGAAVDDGYKQGVLPQRPTLVNLQC 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 162 DIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAK 241
Cdd:PRK07200  161 DIDHPTQSMADLLHLIEHFGGLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLMPEVVEVAK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 242 NNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEERTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTR 321
Cdd:PRK07200  241 KNAKASGGSFRQVNSMEEAFKDADIVYPKSWAPYKVMEERTELYRAGDHEGIKALEKELLAQNAQHKDWHCTEEMMKLTK 320
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1352182024 322 DGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK 396
Cdd:PRK07200  321 DGKALYMHCLPADISGVSCKEGEVTESVFDRYRIALYKEASWKPYIIAAMIFLRKYKNPGALLEQLLKEAQPRVK 395
 
Name Accession Description Interval E-value
PRK07200 PRK07200
aspartate/ornithine carbamoyltransferase family protein; Validated
2-396 0e+00

aspartate/ornithine carbamoyltransferase family protein; Validated


Pssm-ID: 235961 [Multi-domain]  Cd Length: 395  Bit Score: 862.89  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024   2 MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASA 81
Cdd:PRK07200    1 MKTVNELIKDLNSLTSHMHEKDFLLTWEKTPDELKAVLDVADALRALREENISTKVFNSGLGISVFRDNSTRTRFSYASA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  82 LNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQC 161
Cdd:PRK07200   81 CNLLGLEVQDLDEGKSQIAHGETVRETANMISFMADVIGIRDDMYIGKGNAYMREVGAAVDDGYKQGVLPQRPTLVNLQC 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 162 DIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAK 241
Cdd:PRK07200  161 DIDHPTQSMADLLHLIEHFGGLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLMPEVVEVAK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 242 NNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEERTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTR 321
Cdd:PRK07200  241 KNAKASGGSFRQVNSMEEAFKDADIVYPKSWAPYKVMEERTELYRAGDHEGIKALEKELLAQNAQHKDWHCTEEMMKLTK 320
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1352182024 322 DGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK 396
Cdd:PRK07200  321 DGKALYMHCLPADISGVSCKEGEVTESVFDRYRIALYKEASWKPYIIAAMIFLRKYKNPGALLEQLLKEAQPRVK 395
ygeW TIGR03316
knotted carbamoyltransferase YgeW; Members of this protein family include the ygeW gene ...
5-394 0e+00

knotted carbamoyltransferase YgeW; Members of this protein family include the ygeW gene product of Escherichia coli. The function is unknown. Members show homology to ornithine carbamoyltransferase (TIGR00658) and aspartate carbamoyltransferase (carbamoyltransferase), and therefore may belong to the carbamoyltransferases in function. Members often are found in a large, conserved genomic region associated with selenium-dependent molybdenum hydroxylases.


Pssm-ID: 274517 [Multi-domain]  Cd Length: 391  Bit Score: 721.90  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024   5 VNELIKDINSL-TSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALN 83
Cdd:TIGR03316   1 IKEYIEKLNKLdFKKMYNNDFFLTWEKTDDELKAVFTVADALRALRENNISTKIFDSGLGISLFRDNSTRTRFSFASACN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  84 LLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQCDI 163
Cdd:TIGR03316  81 LLGLEVQDLDEGKSQIAHGETVRETANMISFMADVIGIRDDMYIGKGNAYMHEVSDSVQEGYKDGVLEQRPTLVNLQCDI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 164 DHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNN 243
Cdd:TIGR03316 161 DHPTQSMADMLHLIHEFGGIENLKGKKVAMTWAYSPSYGKPLSVPQGVIGLFTRFGMDVVLAHPEGYEVMPEVEEVAKKN 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 244 AKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEERTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTRDG 323
Cdd:TIGR03316 241 AAESGGSFTKTNSMAEAFKDADIVYPKSWAPFAAMEKRTNLYGEGDFAGIDALEKELLAQNATHKDWECTEELMKTTKDG 320
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1352182024 324 EALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQER 394
Cdd:TIGR03316 321 KALYLHCLPADITGVSCEEGEVEASVFDRYRVPLYKEASYKPYIIAAMIFLSKVKNPAATLEKLEEKATPR 391
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
17-373 7.71e-105

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 311.60  E-value: 7.71e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  17 SHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGK 96
Cdd:COG0078     1 TNLKGRHFLSLLDLTPEELRALLDLAAELKAKRKAGIPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDPGD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  97 SQIAHGETVRETANMISFCADAIGIRddmylGAGNAYMREVGAAlddgykqgvlpQRPALVNLQCDIDHPTQSMADLAWL 176
Cdd:COG0078    81 SQLGRGESIKDTARVLSRYVDGIMIR-----TFGHETLEELAKY-----------AGVPVINGLTDLFHPCQALADLLTI 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 177 REHFGSlenLKGKKIAMTWAyspsygkPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTS 256
Cdd:COG0078   145 REHFGK---LKGLKVAYVGD-------GNNVANSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAESGGSITITHD 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 257 MEEAFKDADIVYPKSWAPykvMEErtellrandheglkalEKQCLAQNAQHKDWHCTEEMMELTRDgEALYMHCLPADIs 336
Cdd:COG0078   215 PAEAVKGADVVYTDVWVS---MGQ----------------EEEAEERIKAFKPYQVNEELMALAKP-DAIFMHCLPAHR- 273
                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 1352182024 337 gvsckEGEVTEGVFEKYRIATYKEASWKPYIIAAMIL 373
Cdd:COG0078   274 -----GEEVTDEVIDGPQSVVFDEAENRLHAQKALLA 305
OTCace pfam00185
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;
190-374 5.52e-36

Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;


Pssm-ID: 425511 [Multi-domain]  Cd Length: 154  Bit Score: 128.88  E-value: 5.52e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 190 KIAMTWayspsyGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVYP 269
Cdd:pfam00185   1 KIAYVG------DGHNNVAHSLIIAAAKLGMDVRLATPKGYPPDPEVLDKAKKIAEKSGGSIEITDDPAEAVKGADVVYT 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 270 KSWAPykvMEErtellrandheglkalEKQCLAQNAQHKDWHCTEEMMELTRDgEALYMHCLPADisgvscKEGEVTEGV 349
Cdd:pfam00185  75 DVWQS---MGQ----------------EKEREERLKAFKPYQVNEELMKLAKK-DAIFMHCLPAH------RGEEVTDDV 128
                         170       180
                  ....*....|....*....|....*
gi 1352182024 350 FEKYRIATYKEASWKPYIIAAMILS 374
Cdd:pfam00185 129 FDGPRSVVFDQAENRLHAQKALLAL 153
 
Name Accession Description Interval E-value
PRK07200 PRK07200
aspartate/ornithine carbamoyltransferase family protein; Validated
2-396 0e+00

aspartate/ornithine carbamoyltransferase family protein; Validated


Pssm-ID: 235961 [Multi-domain]  Cd Length: 395  Bit Score: 862.89  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024   2 MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASA 81
Cdd:PRK07200    1 MKTVNELIKDLNSLTSHMHEKDFLLTWEKTPDELKAVLDVADALRALREENISTKVFNSGLGISVFRDNSTRTRFSYASA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  82 LNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQC 161
Cdd:PRK07200   81 CNLLGLEVQDLDEGKSQIAHGETVRETANMISFMADVIGIRDDMYIGKGNAYMREVGAAVDDGYKQGVLPQRPTLVNLQC 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 162 DIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAK 241
Cdd:PRK07200  161 DIDHPTQSMADLLHLIEHFGGLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLMPEVVEVAK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 242 NNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEERTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTR 321
Cdd:PRK07200  241 KNAKASGGSFRQVNSMEEAFKDADIVYPKSWAPYKVMEERTELYRAGDHEGIKALEKELLAQNAQHKDWHCTEEMMKLTK 320
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1352182024 322 DGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK 396
Cdd:PRK07200  321 DGKALYMHCLPADISGVSCKEGEVTESVFDRYRIALYKEASWKPYIIAAMIFLRKYKNPGALLEQLLKEAQPRVK 395
ygeW TIGR03316
knotted carbamoyltransferase YgeW; Members of this protein family include the ygeW gene ...
5-394 0e+00

knotted carbamoyltransferase YgeW; Members of this protein family include the ygeW gene product of Escherichia coli. The function is unknown. Members show homology to ornithine carbamoyltransferase (TIGR00658) and aspartate carbamoyltransferase (carbamoyltransferase), and therefore may belong to the carbamoyltransferases in function. Members often are found in a large, conserved genomic region associated with selenium-dependent molybdenum hydroxylases.


Pssm-ID: 274517 [Multi-domain]  Cd Length: 391  Bit Score: 721.90  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024   5 VNELIKDINSL-TSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALN 83
Cdd:TIGR03316   1 IKEYIEKLNKLdFKKMYNNDFFLTWEKTDDELKAVFTVADALRALRENNISTKIFDSGLGISLFRDNSTRTRFSFASACN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  84 LLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQCDI 163
Cdd:TIGR03316  81 LLGLEVQDLDEGKSQIAHGETVRETANMISFMADVIGIRDDMYIGKGNAYMHEVSDSVQEGYKDGVLEQRPTLVNLQCDI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 164 DHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNN 243
Cdd:TIGR03316 161 DHPTQSMADMLHLIHEFGGIENLKGKKVAMTWAYSPSYGKPLSVPQGVIGLFTRFGMDVVLAHPEGYEVMPEVEEVAKKN 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 244 AKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEERTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTRDG 323
Cdd:TIGR03316 241 AAESGGSFTKTNSMAEAFKDADIVYPKSWAPFAAMEKRTNLYGEGDFAGIDALEKELLAQNATHKDWECTEELMKTTKDG 320
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1352182024 324 EALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQER 394
Cdd:TIGR03316 321 KALYLHCLPADITGVSCEEGEVEASVFDRYRVPLYKEASYKPYIIAAMIFLSKVKNPAATLEKLEEKATPR 391
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
17-373 7.71e-105

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 311.60  E-value: 7.71e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  17 SHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGK 96
Cdd:COG0078     1 TNLKGRHFLSLLDLTPEELRALLDLAAELKAKRKAGIPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDPGD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  97 SQIAHGETVRETANMISFCADAIGIRddmylGAGNAYMREVGAAlddgykqgvlpQRPALVNLQCDIDHPTQSMADLAWL 176
Cdd:COG0078    81 SQLGRGESIKDTARVLSRYVDGIMIR-----TFGHETLEELAKY-----------AGVPVINGLTDLFHPCQALADLLTI 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 177 REHFGSlenLKGKKIAMTWAyspsygkPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTS 256
Cdd:COG0078   145 REHFGK---LKGLKVAYVGD-------GNNVANSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAESGGSITITHD 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 257 MEEAFKDADIVYPKSWAPykvMEErtellrandheglkalEKQCLAQNAQHKDWHCTEEMMELTRDgEALYMHCLPADIs 336
Cdd:COG0078   215 PAEAVKGADVVYTDVWVS---MGQ----------------EEEAEERIKAFKPYQVNEELMALAKP-DAIFMHCLPAHR- 273
                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 1352182024 337 gvsckEGEVTEGVFEKYRIATYKEASWKPYIIAAMIL 373
Cdd:COG0078   274 -----GEEVTDEVIDGPQSVVFDEAENRLHAQKALLA 305
PRK04523 PRK04523
N-acetylornithine carbamoyltransferase; Reviewed
22-332 8.90e-46

N-acetylornithine carbamoyltransferase; Reviewed


Pssm-ID: 235304 [Multi-domain]  Cd Length: 335  Bit Score: 160.30  E-value: 8.90e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  22 KDFLLTWEQTPDELKQVLDVAAALKALRaenISTKVFNSGLGIsVFRDNSTRTRFSYASALNLLGLAQQDLDEGKS--QI 99
Cdd:PRK04523    4 KHFLNTQDWSRAELDALLTQAAAFKRNK---LGSALKGKSIAL-VFFNPSLRTRTSFELGAFQLGGHAVVLQPGKDawPI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 100 AHG----------ETVRETANMISFCADAIGIRddmylgagnAYMREVGAALDdgyKQGVLPQRPA------LVNLQcDI 163
Cdd:PRK04523   80 EFElgavmdgeteEHIREVARVLSRYVDLIGVR---------AFPKFVDWSKD---RQDQVLNSFAkystvpVINME-TI 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 164 DHPTQSMADLAWLREHFGSLenLKGKKIAMTWAYSPsygKPL--SVPQGIIGLMTRFGMDVTLAHP-EGYDLIPDVVEVA 240
Cdd:PRK04523  147 THPCQELAHALALQEHFGTT--LRGKKYVLTWTYHP---KPLntAVANSALLIATRLGMDVTLLCPtPDYILDERYMDWA 221
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 241 KNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVME--ERTELLRandheglkalekqclaqnAQHKDWHCTEEMME 318
Cdd:PRK04523  222 EQNAAESGGSLTVSHDIDSAYAGADVVYAKSWGALPFFGnwEPEKPIR------------------DQYQHFIVDERKMA 283
                         330
                  ....*....|....
gi 1352182024 319 LTRDGeaLYMHCLP 332
Cdd:PRK04523  284 LTNNG--VFSHCLP 295
orni_carb_tr TIGR00658
ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in ...
22-373 8.06e-42

ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in a superfamily with the related enzyme aspartate carbamoyltransferase. Most known examples are anabolic, playing a role in arginine biosynthesis, but some are catabolic. Most OTCases are homotrimers, but the homotrimers are organized into dodecamers built from four trimers in at least two species; the catabolic OTCase of Pseudomonas aeruginosa is allosterically regulated, while OTCase of the extreme thermophile Pyrococcus furiosus shows both allostery and thermophily. [Amino acid biosynthesis, Glutamate family]


Pssm-ID: 129743 [Multi-domain]  Cd Length: 304  Bit Score: 149.04  E-value: 8.06e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  22 KDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFnSGLGIS-VFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIA 100
Cdd:TIGR00658   1 RHLLSLLDLSPEEIRYLLQLAKKLKKGKKKGKEHKKL-KGKTLAlIFEKPSTRTRVSFEVAAYQLGGHPLYLNPNDLQLG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 101 HGETVRETANMISFCADAIGIRddmylgagnaymrevgaalddGYKQGVLpQRPA------LVNLQCDIDHPTQSMADLA 174
Cdd:TIGR00658  80 RGESIKDTARVLSRYVDGIMAR---------------------VYKHEDV-EELAkyasvpVINGLTDLFHPCQALADLL 137
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 175 WLREHFGSLENLKgkkiaMTWAyspsyGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQV 254
Cdd:TIGR00658 138 TIIEHFGKLKGVK-----VVYV-----GDGNNVCNSLMLAGAKLGMDVVVATPEGYEPDADIVKKAQEIAKENGGSVELT 207
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 255 TSMEEAFKDADIVYPKSWAPykvMEERTEllranDHEGLKALekqclaqnaqhKDWHCTEEMMELTRDgEALYMHCLPAD 334
Cdd:TIGR00658 208 HDPVEAVKGADVIYTDVWVS---MGEEDK-----KEERLKLF-----------RPYQVNEELMELAKP-EVIFMHCLPAH 267
                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1352182024 335 isgvscKEGEVTEGVFEKYRIATYKEASWKPYIIAAMIL 373
Cdd:TIGR00658 268 ------RGEEVTDEVIEGPHSIVFDQAENRLHAQKAVMV 300
PRK00779 PRK00779
ornithine carbamoyltransferase; Provisional
22-351 1.66e-40

ornithine carbamoyltransferase; Provisional


Pssm-ID: 234835 [Multi-domain]  Cd Length: 304  Bit Score: 145.62  E-value: 1.66e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  22 KDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVF-NSGLGIsVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIA 100
Cdd:PRK00779    5 RHFLSLDDLSPEELEELLDLAAELKKKRKAGEPHPPLkGKTLAM-IFEKPSTRTRVSFEVGMAQLGGHAIFLSPRDTQLG 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 101 HGETVRETANMISFCADAIGIRDdmylgagnaymrevgaalddgYKQGVL---------PqrpaLVNLQCDIDHPTQSMA 171
Cdd:PRK00779   84 RGEPIEDTARVLSRYVDAIMIRT---------------------FEHETLeelaeystvP----VINGLTDLSHPCQILA 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 172 DLAWLREHFGSLenlKGKKIAmtW-------AYSpsygkplsvpqgiigLM---TRFGMDVTLAHPEGYDLIPDVVEvak 241
Cdd:PRK00779  139 DLLTIYEHRGSL---KGLKVA--WvgdgnnvANS---------------LLlaaALLGFDLRVATPKGYEPDPEIVE--- 195
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 242 NNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPykvM--EERTEllrandhEGLKALekqclaqnaqhKDWHCTEEMMEL 319
Cdd:PRK00779  196 KIAKETGASIEVTHDPKEAVKGADVVYTDVWVS---MgqEAEAE-------ERLKAF-----------APYQVNEELMAL 254
                         330       340       350
                  ....*....|....*....|....*....|..
gi 1352182024 320 TRDgEALYMHCLPADisgvscKEGEVTEGVFE 351
Cdd:PRK00779  255 AKP-DAIFMHCLPAH------RGEEVTDEVID 279
OTCace pfam00185
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;
190-374 5.52e-36

Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;


Pssm-ID: 425511 [Multi-domain]  Cd Length: 154  Bit Score: 128.88  E-value: 5.52e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 190 KIAMTWayspsyGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVYP 269
Cdd:pfam00185   1 KIAYVG------DGHNNVAHSLIIAAAKLGMDVRLATPKGYPPDPEVLDKAKKIAEKSGGSIEITDDPAEAVKGADVVYT 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 270 KSWAPykvMEErtellrandheglkalEKQCLAQNAQHKDWHCTEEMMELTRDgEALYMHCLPADisgvscKEGEVTEGV 349
Cdd:pfam00185  75 DVWQS---MGQ----------------EKEREERLKAFKPYQVNEELMKLAKK-DAIFMHCLPAH------RGEEVTDDV 128
                         170       180
                  ....*....|....*....|....*
gi 1352182024 350 FEKYRIATYKEASWKPYIIAAMILS 374
Cdd:pfam00185 129 FDGPRSVVFDQAENRLHAQKALLAL 153
OTCace_N pfam02729
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;
23-178 5.79e-32

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;


Pssm-ID: 460665 [Multi-domain]  Cd Length: 140  Bit Score: 117.91  E-value: 5.79e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  23 DFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHG 102
Cdd:pfam02729   1 HFLSLEDLSREEIEALLDLAAELKEARKRGKKLPLLKGKTVALLFEEPSTRTRVSFEVAAKRLGGHVIYLSSSDIQLSSG 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1352182024 103 ETVRETANMISFCADAIGIRddmylGAGNAYMREVGAAlddgykqgvlpQRPALVNLQCDIDHPTQSMADLAWLRE 178
Cdd:pfam02729  81 ESLADTARVLSRYVDAIVIR-----HFGHEDLEELAEY-----------ASVPVINAGGDHEHPTQALADLLTIRE 140
PRK02102 PRK02102
ornithine carbamoyltransferase; Validated
17-374 1.08e-31

ornithine carbamoyltransferase; Validated


Pssm-ID: 179366 [Multi-domain]  Cd Length: 331  Bit Score: 122.69  E-value: 1.08e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  17 SHLHEKDFlltweqTPDELKQVLDVAAALKALRAENISTKVFnSGLGIS-VFRDNSTRTRFSYASALNLLGLAQQDLDEG 95
Cdd:PRK02102    9 SFLKLLDF------TPEEIEYLIDLSIELKAAKKAGIEHQYL-EGKNIAlIFEKTSTRTRCAFEVAAIDLGAHVTYLGPN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  96 KSQIAHGETVRETANMISFCADAIGIRddmylgagnaymrevgaalddGYKQ----------GVlPQRPALVnlqcDIDH 165
Cdd:PRK02102   82 DSQLGKKESIEDTARVLGRMYDGIEYR---------------------GFKQeiveelakysGV-PVWNGLT----DEWH 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 166 PTQSMADLAWLREHFGSLENLKgkkiamtWAYspsygkplsvpqgiIG---------LM---TRFGMDVTLAHPEGYDLI 233
Cdd:PRK02102  136 PTQMLADFMTMKEHFGPLKGLK-------LAY--------------VGdgrnnmansLMvggAKLGMDVRICAPKELWPE 194
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 234 PDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVY---------PKSWapykvmEERTELLrandheglkalekqclaqn 304
Cdd:PRK02102  195 EELVALAREIAKETGAKITITEDPEEAVKGADVIYtdvwvsmgeEDEW------EERIKLL------------------- 249
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 305 aqhKDWHCTEEMMELTRDGEALYMHCLPA----------DISGVSCKEG-EVTEGVFEKYRIATYKEASWKPYIIAAMIL 373
Cdd:PRK02102  250 ---KPYQVNMDLMKATGNPDVIFMHCLPAfhdtetkvgkEIAEKYGLKGlEVTDEVFESKYSIVFDEAENRMHTIKAVMV 326

                  .
gi 1352182024 374 S 374
Cdd:PRK02102  327 A 327
PLN02342 PLN02342
ornithine carbamoyltransferase
21-387 1.70e-25

ornithine carbamoyltransferase


Pssm-ID: 177976 [Multi-domain]  Cd Length: 348  Bit Score: 106.03  E-value: 1.70e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  21 EKDFLLTWEQTPDELKQVLDVAAALKA-LRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQI 99
Cdd:PLN02342   45 PKHFLHIDDFDKEEILGLLDRAKEVKAlLKSGDRSFQPFKGKSMAMIFTKPSMRTRVSFETGFFLLGGHALYLGPDDIQL 124
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 100 AHGETVRETANMISFCADAIgirddmylgagnayMREVGAALD--DGYKQGVLPqrpaLVNLQCDIDHPTQSMADLAWLR 177
Cdd:PLN02342  125 GKREETRDIARVLSRYNDII--------------MARVFAHQDvlDLAEYSSVP----VINGLTDYNHPCQIMADALTII 186
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 178 EHFGSLENLK------GKKIAMTWAYspsygkplsvpqgiigLMTRFGMDVTLAHPEGYDLIPDVVEvaknNAKASGGSF 251
Cdd:PLN02342  187 EHIGRLEGTKvvyvgdGNNIVHSWLL----------------LAAVLPFHFVCACPKGYEPDAKTVE----KARAAGISK 246
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 252 RQVTS-MEEAFKDADIVYPKSWAPYKVMEERTEllRANDHEGLKALEKqclaqnaqhkdwhcteeMMELTRDGeALYMHC 330
Cdd:PLN02342  247 IEITNdPAEAVKGADVVYTDVWASMGQKEEAEK--RKKAFQGFQVNEA-----------------LMKLAGPQ-AYFMHC 306
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1352182024 331 LPADisgvscKEGEVTEGVFEKYRIATYKEASwkpyiiaamilSRKYAKPGALLEQL 387
Cdd:PLN02342  307 LPAE------RGVEVTDGVMEAPNSIVFPQAE-----------NRMHAQNAIMLHQL 346
PRK04284 PRK04284
ornithine carbamoyltransferase; Provisional
19-374 9.85e-25

ornithine carbamoyltransferase; Provisional


Pssm-ID: 235269 [Multi-domain]  Cd Length: 332  Bit Score: 103.28  E-value: 9.85e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  19 LHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQ 98
Cdd:PRK04284    4 LRNRSFLTLLDFTPKEIEYLLDLSEDLKRAKYAGIEVQKLKGKNIALIFEKDSTRTRCAFEVAAYDQGAHVTYLGPTGSQ 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  99 IAHGETVRETANMISFCADAIGIRddmylgagnaymrevgaalddGYKQ----------GVlpqrpALVNLQCDIDHPTQ 168
Cdd:PRK04284   84 MGKKESTKDTARVLGGMYDGIEYR---------------------GFSQrtvetlaeysGV-----PVWNGLTDEDHPTQ 137
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 169 SMADLAWLREHF-GSLENLKgkkiaMTW--------AYSPSYGKPLsvpqgiiglmtrFGMDVTLAHPEGYDLIPDVVEV 239
Cdd:PRK04284  138 VLADFLTAKEHLkKPYKDIK-----FTYvgdgrnnvANALMQGAAI------------MGMDFHLVCPKELNPDDELLNK 200
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 240 AKNNAKASGGSFRQVTSMEEAFKDADIVYPKSWA----PYKVMEERTELLRAndheglkalekqclaqnaqhkdWHCTEE 315
Cdd:PRK04284  201 CKEIAAETGGKITITDDIDEGVKGSDVIYTDVWVsmgePDEVWEERIKLLKP----------------------YQVNKE 258
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 316 MMELTRDGEALYMHCLPA--DISGVSCK---------EGEVTEGVFEKYRIATYKEASWKPYIIAAMILS 374
Cdd:PRK04284  259 MMKKTGNPNAIFEHCLPSfhDLDTKVGKeifekyglkEMEVTDEVFESKASVVFDEAENRMHTIKAVMVA 328
pyrB PRK00856
aspartate carbamoyltransferase catalytic subunit;
25-268 4.97e-21

aspartate carbamoyltransferase catalytic subunit;


Pssm-ID: 234849 [Multi-domain]  Cd Length: 305  Bit Score: 92.44  E-value: 4.97e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  25 LLTWEQ-TPDELKQVLDVAAALKALRAENISTKVFNSGLGI-SVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHG 102
Cdd:PRK00856    8 LLSIEDlSREEIELLLDTAEEFKEVLRREVKKVPLLRGKTVaNLFFEPSTRTRLSFELAAKRLGADVINFSASTSSVSKG 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 103 ETVRETANMIS-FCADAIGIRDDMylgAGNAYM--REVGAAL---DDGYKQgvlpqrpalvnlqcdidHPTQSMADLAWL 176
Cdd:PRK00856   88 ETLADTIRTLSaMGADAIVIRHPQ---SGAARLlaESSDVPVinaGDGSHQ-----------------HPTQALLDLLTI 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 177 REHFGSLENLkgkKIAmtwayspsygkplsvpqgIIG-------------LMTRFGMDVTLAHPEGydLIPDVVEvaknn 243
Cdd:PRK00856  148 REEFGRLEGL---KVA------------------IVGdikhsrvarsniqALTRLGAEVRLIAPPT--LLPEGMP----- 199
                         250       260
                  ....*....|....*....|....*
gi 1352182024 244 akasggSFRQVTSMEEAFKDADIVY 268
Cdd:PRK00856  200 ------EYGVHTDLDEVIEDADVVM 218
PRK14805 PRK14805
ornithine carbamoyltransferase; Provisional
22-351 1.89e-20

ornithine carbamoyltransferase; Provisional


Pssm-ID: 237819 [Multi-domain]  Cd Length: 302  Bit Score: 90.90  E-value: 1.89e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  22 KDFLLTWEQTPDELKQVLDVAAALKALRAEnistkvFNSGL-GISV---FRDNSTRTRFSYASALNLLG-----LAQQDL 92
Cdd:PRK14805    2 KHLLSIKELTQQQLLDLLALAKTIKANPAE------YRQALaGKSVvmlFEKPSLRTRVSFDIGINKLGghclyLDQQNG 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  93 DEGKSqiahgETVRETANMISFCADAIGIRDDMYlgagnaymrevgAALDDGYKQGVLPqrpaLVNLQCDIDHPTQSMAD 172
Cdd:PRK14805   76 ALGKR-----ESVADFAANLSCWADAIVARVFSH------------STIEQLAEHGSVP----VINALCDLYHPCQALAD 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 173 LAWLREHFGSLENLKgkkiamtWAYspsYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFr 252
Cdd:PRK14805  135 FLTLAEQFGDVSKVK-------LAY---VGDGNNVTHSLMYGAAILGATMTVICPPGHFPDGQIVAEAQELAAKSGGKL- 203
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 253 QVTSMEEAFKDADIVYPKSWAPykvMEERTELlrandhEGLKalekqclaqnAQHKDWHCTEEMMELTrdGEALYMHCLP 332
Cdd:PRK14805  204 VLTSDIEAIEGHDAIYTDTWIS---MGDDTPL------AEIK----------AKFAPYQVNKALMEKA--GATFVMHCQP 262
                         330
                  ....*....|....*....
gi 1352182024 333 ADisgvscKEGEVTEGVFE 351
Cdd:PRK14805  263 AH------RGVEITSEVMD 275
PRK03515 PRK03515
ornithine carbamoyltransferase subunit I; Provisional
17-374 1.17e-19

ornithine carbamoyltransferase subunit I; Provisional


Pssm-ID: 179587 [Multi-domain]  Cd Length: 336  Bit Score: 89.00  E-value: 1.17e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  17 SHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNsGLGIS-VFRDNSTRTRFSYASALNLLGLAQQDLDEG 95
Cdd:PRK03515    2 NQFYQRHFLRLLDFTPAELNSLLQLAAKLKADKKNGKEEQKLT-GKNIAlIFEKDSTRTRCSFEVAAYDQGARVTYLGPS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  96 KSQIAHGETVRETANMISFCADAIGIRddmylgagnaymrevgaalddGYKQGVL---------PQRPALVNLQcdidHP 166
Cdd:PRK03515   81 GSQIGHKESIKDTARVLGRMYDGIQYR---------------------GYGQEIVetlaeyagvPVWNGLTNEF----HP 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 167 TQSMADLAWLREHfgslenLKGKKI-AMTWAY----SPSYGKPLSVPQGIIglmtrfGMDVTLAHPEGYDLIPDVVEVAK 241
Cdd:PRK03515  136 TQLLADLLTMQEH------LPGKAFnEMTLAYagdaRNNMGNSLLEAAALT------GLDLRLVAPKACWPEAALVTECR 203
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 242 NNAKASGGSFRQVTSMEEAFKDADIVYPKSWA----PYKVMEERTELLRandheglkalekqclaqnaqhkDWHCTEEMM 317
Cdd:PRK03515  204 ALAQKNGGNITLTEDIAEGVKGADFIYTDVWVsmgePKEVWAERIALLR----------------------PYQVNSKMM 261
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1352182024 318 ELTRDGEALYMHCLPA-----DISGVSCKEG-------EVTEGVFEKYRIATYKEASWKPYIIAAMILS 374
Cdd:PRK03515  262 QLTGNPQVKFLHCLPAfhddqTTLGKKMAEEyglhggmEVTDEVFESAHSIVFDQAENRLHTIKAVMVA 330
PRK01713 PRK01713
ornithine carbamoyltransferase; Provisional
18-374 3.26e-18

ornithine carbamoyltransferase; Provisional


Pssm-ID: 167263 [Multi-domain]  Cd Length: 334  Bit Score: 85.04  E-value: 3.26e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  18 HLHEKDFLLTWEQTPDELKQVLDVAAALKalRAENISTKVFN-SGLGIS-VFRDNSTRTRFSYASALNLLGLAQQDLDEG 95
Cdd:PRK01713    4 NLKNRHLLSLVNHTEREIKYLLDLSRDLK--RAKYAGTEQQRlKGKNIAlIFEKTSTRTRCAFEVAAYDQGAQVTYIDPN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  96 KSQIAHGETVRETANMISFCADAIGIRddmylgagnaymrevgaalddGYKQGVLPQRP-----ALVNLQCDIDHPTQSM 170
Cdd:PRK01713   82 SSQIGHKESMKDTARVLGRMYDAIEYR---------------------GFKQSIVNELAeyagvPVFNGLTDEFHPTQML 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 171 ADLAWLREHFGSLENlkgkkiAMTWAYSPSYGKPLSVPQGIIGlmTRFGMDVTLAHPEGydLIPD--VVEVAKNNAKASG 248
Cdd:PRK01713  141 ADVLTMIENCDKPLS------EISYVYIGDARNNMGNSLLLIG--AKLGMDVRICAPKA--LLPEasLVEMCEKFAKESG 210
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 249 GSFRQVTSMEEAFKDADIVYPKSWA----PYKVMEERTELLRAndheglkalekqclaqnaqhkdWHCTEEMMELTRDGE 324
Cdd:PRK01713  211 ARITVTDDIDKAVKGVDFVHTDVWVsmgePLETWGERIKLLMP----------------------YQVTPELMKRTGNPK 268
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1352182024 325 ALYMHCLPAdISGVSCKEG--------------EVTEGVFEKYRIATYKEASWKPYIIAAMILS 374
Cdd:PRK01713  269 VKFMHCLPA-FHNSETKVGrqiaekypelangiEVTEDVFESPMNIAFEQAENRMHTIKAVMVA 331
PRK12562 PRK12562
ornithine carbamoyltransferase subunit F; Provisional
17-374 8.63e-18

ornithine carbamoyltransferase subunit F; Provisional


Pssm-ID: 105755  Cd Length: 334  Bit Score: 83.57  E-value: 8.63e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  17 SHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFnSGLGIS-VFRDNSTRTRFSYASALNLLGLAQQDLDEG 95
Cdd:PRK12562    2 SGFYKKHFLKLLDFTPAELNSLLQLAAKLKADKKNGKEVARL-TGKNIAlIFEKDSTRTRCSFEVAAYDQGARVTYLGPS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  96 KSQIAHGETVRETANMISFCADAIgirddMYLGAGnaymREVGAALDDgyKQGVlPQRPALVNLQcdidHPTQSMADLAW 175
Cdd:PRK12562   81 GSQIGHKESIKDTARVLGRMYDGI-----QYRGHG----QEVVETLAE--YAGV-PVWNGLTNEF----HPTQLLADLLT 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 176 LREHfgslenLKGKKI-AMTWAYSPSYGKPLSvpQGIIGLMTRFGMDVTLAHPEGydLIPDVVEVAKNNAKA--SGGSFR 252
Cdd:PRK12562  145 MQEH------LPGKAFnEMTLVYAGDARNNMG--NSMLEAAALTGLDLRLVAPQA--CWPEASLVAECSALAqkHGGKIT 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 253 QVTSMEEAFKDADIVYPKSWA----PYKVMEERTELLRandheglkalekqclaqnaqhkDWHCTEEMMELTRDGEALYM 328
Cdd:PRK12562  215 LTEDIAAGVKGADFIYTDVWVsmgePKEKWAERIALLR----------------------GYQVNSKMMALTGNPQVKFL 272
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1352182024 329 HCLPA---DISGVSCKEG---------EVTEGVFEKYRIATYKEASWKPYIIAAMILS 374
Cdd:PRK12562  273 HCLPAfhdDQTTLGKKMAkefglhggmEVTDEVFESPASIVFDQAENRMHTIKAVMVA 330
PRK11891 PRK11891
aspartate carbamoyltransferase; Provisional
25-334 4.39e-10

aspartate carbamoyltransferase; Provisional


Pssm-ID: 183362 [Multi-domain]  Cd Length: 429  Bit Score: 61.03  E-value: 4.39e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  25 LLTWEQ-TPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQD-LDEGKSQIAHG 102
Cdd:PRK11891   90 LLSVDQfSRDSVEALFRVADVMQPIARRQKISRVLEGAVLGNLFFEASTRTRVSFGAAFCRLGGSVCDtTGFTFSSMAKG 169
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 103 ETVRETANMISFCADAIGIRDDMyLGAGNAYMREVGAALDDGykqGVLPQrpalvnlqcdiDHPTQSMADLAWLREHFGS 182
Cdd:PRK11891  170 ESIYDTSRVMSGYVDALVIRHPE-QGSVAEFARATNLPVING---GDGPG-----------EHPSQALLDLYTIQREFSR 234
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 183 LENL-KGKKIAMTWAYspSYGKPLsvpQGIIGLMTRF-GMDVTLAHPEGYDLIPDVVEVAKNNakasGGSFRQVTSMEEA 260
Cdd:PRK11891  235 LGKIvDGAHIALVGDL--KYGRTV---HSLVKLLALYrGLKFTLVSPPTLEMPAYIVEQISRN----GHVIEQTDDLAAG 305
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1352182024 261 FKDADIVYPKswapyKVMEERTellrANDH-EGLKAlekqclaqnaqhkDWHCTEEMMELTRDGEALYMHCLPAD 334
Cdd:PRK11891  306 LRGADVVYAT-----RIQKERF----ADESfEGYTP-------------DFQINQALVDAVCKPDTLIMHPLPRD 358
PRK08192 PRK08192
aspartate carbamoyltransferase; Provisional
33-334 3.72e-08

aspartate carbamoyltransferase; Provisional


Pssm-ID: 169269 [Multi-domain]  Cd Length: 338  Bit Score: 54.73  E-value: 3.72e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  33 DELKQVLDVAAALK--ALRAEniSTKVFNSGLGISVFRDNSTRTRFSYASALNLL-GLAQQDLDEGKSQIAHGETVRETA 109
Cdd:PRK08192   17 DAIQRIFNVADRMEpyALREK--RTRVLEGAILGNLFFEPSTRTRVSFGCAFNLLgGHVRETTGMASSSLSKGESLYDTA 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 110 NMISFCADAIGIRD-DMYLGAGNAYMREV----GAaldDGYKQgvlpqrpalvnlqcdidHPTQSMADLAWLR---EHFG 181
Cdd:PRK08192   95 RVLSTYSDVIAMRHpDAGSVKEFAEGSRVpvinGG---DGSNE-----------------HPTQALLDLFTIQkelAHAG 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 182 slENLKGKKIAMTWAYspSYGKPLSVPQGIIGLMTRfgMDVTLAHPEGYDLiPDVVEVAKNNAkasGGSFRQVTSMEEAF 261
Cdd:PRK08192  155 --RGIDGMHIAMVGDL--KFGRTVHSLSRLLCMYKN--VSFTLVSPKELAM-PDYVISDIENA---GHKITITDQLEGNL 224
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1352182024 262 KDADIVYPKswapyKVMEERTELLR-ANDHEGLKALEKQCLAQnaqhkdwHCteemmeltrDGEALYMHCLPAD 334
Cdd:PRK08192  225 DKADILYLT-----RIQEERFPSQEeANKYRGKFRLNQSIYTQ-------HC---------KSNTVIMHPLPRD 277
PLN02527 PLN02527
aspartate carbamoyltransferase
35-268 6.21e-06

aspartate carbamoyltransferase


Pssm-ID: 178142 [Multi-domain]  Cd Length: 306  Bit Score: 47.43  E-value: 6.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  35 LKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGK--SQIAHGETVRETANMI 112
Cdd:PLN02527   14 LELLFEVAREMEKVERGSPGSQMLKGYLMATLFYEPSTRTRLSFESAMKRLGGEVLTTENAGefSSAAKGETLEDTIRTV 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 113 SFCADAIGIRddmYLGAGNAymREVGAALD-------DGYKQgvlpqrpalvnlqcdidHPTQSMADLAWLREHFGSLEN 185
Cdd:PLN02527   94 EGYSDIIVLR---HFESGAA--RRAAATAEipvinagDGPGQ-----------------HPTQALLDVYTIQREIGRLDG 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 186 LkgkKIAMTWAYspSYGKPLsvpQGIIGLMTRFGmDVTLahpegYDLIPDVVEVA---KNNAKASGGSFRQVTSMEEAFK 262
Cdd:PLN02527  152 I---KVGLVGDL--ANGRTV---RSLAYLLAKYE-DVKI-----YFVAPDVVKMKddiKDYLTSKGVEWEESSDLMEVAS 217

                  ....*.
gi 1352182024 263 DADIVY 268
Cdd:PLN02527  218 KCDVLY 223
PRK14804 PRK14804
ornithine carbamoyltransferase; Provisional
25-272 7.81e-06

ornithine carbamoyltransferase; Provisional


Pssm-ID: 173265 [Multi-domain]  Cd Length: 311  Bit Score: 47.33  E-value: 7.81e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024  25 LLTWEQTPD-ELKQVLDVAAALKALRAeNISTKVFNSGLGIsVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGE 103
Cdd:PRK14804    9 LISWEDWSDsEILDLLDFAVHVKKNRV-NYAGHMSGRSLAM-LFQKTSTRTRVSFEVAMTEMGGHGIYLDWMASNFQLSD 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 104 T---VRETANMISFCADAIGIRDDMYLgagnaymrevgaalddgYKQGvlPQRPaLVNLQCDIDHPTQSMADLAWLrehf 180
Cdd:PRK14804   87 IdleARYLSRNVSVIMARLKKHEDLLV-----------------MKNG--SQVP-VINGCDNMFHPCQSLADIMTI---- 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1352182024 181 gSLE--NLKGKKIAMTWayspsYGKPLSVPQGIIGLMTRFGMDVTLAHP--EGYDLIPDVVEVAKnnakaSGGSFRQVTS 256
Cdd:PRK14804  143 -ALDspEIPLNQKQLTY-----IGVHNNVVNSLIGITAALGIHLTLVTPiaAKENIHAQTVERAK-----KKGTLSWEMN 211
                         250
                  ....*....|....*.
gi 1352182024 257 MEEAFKDADIVYPKSW 272
Cdd:PRK14804  212 LHKAVSHADYVYTDTW 227
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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