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Conserved domains on  [gi|1359192519|gb|AVN49849|]
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Fe(3+)-hydroxamate ABC transporter permease FhuB [Serratia marcescens]

Protein Classification

iron ABC transporter permease( domain architecture ID 11484808)

iron ABC transporter permease is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

Gene Ontology:  GO:0022857|GO:0006826|GO:0043190|GO:0140359|GO:0042626|GO:0016020
PubMed:  15574383|25750732|24638992|18535149|17723295
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
1-660 0e+00

Fe(3+)-hydroxamate ABC transporter permease FhuB;


:

Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 681.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519   1 MSSGIRKLPLTLILLLLAAAGGLTIYNLAQQLPPAQWARALSAPDIDDVRQMLFHYSLLPRLTVSLLAGAGLGLVGVLFQ 80
Cdd:PRK10577    5 MSRRRARLPALLLALLLLLALALTLTQLSAALPLSQWLQALWGPDADDLEQLLLHYSRLPRLAIALLVGAALGLAGALLQ 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  81 QVLRNPLAEPSTLGVAAGAQLGLTIATLWVLPGGEFTRQLAAMVGAIVVGGLVFGVAWGKRMSPVTLILAGLVLGLYCGA 160
Cdd:PRK10577   85 QVLRNPLASPTTLGVAAGAQLALVLATLFAPALLALASQLAAFAGGLLAAALVFALAGGKRLSPLRLVLAGMVVSLYLGA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 161 VNSLLALFNYDQLQGMFLWGTGALNQQDWSAVQFLLPRLLVAGLLAALLLRPLTLLGLDDGVARNLGLGLSMARFCALGV 240
Cdd:PRK10577  165 LTTLLLLFNEQYLQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAALAL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 241 AIIFSAMLVSAVGVIGFIGLFAPLMAKMLGARRLAHRMMLAPLLGALLLWLTDQVMLGVTQVW-HEIPTGAATALFGAPL 319
Cdd:PRK10577  245 AVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARLPLSPLIGALLLLLTDQLVRLLAGVGgELLPTGAVTALIGAPL 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 320 LLWLLPRLRSAATPPPMNLGDKVPAERGNLPGWILVGGLVLLIGLALALMLGKNAGGWHWSLGVELDALLPWRWPRVLSA 399
Cdd:PRK10577  325 LLWLLPRLRSAQSAPAMSAGDRVAARRRRVLAWLLALGLLLLLALVVALSFGRDAHGWNWLSGQLLDALLPLRLPRLLAA 404

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 400 LAAGMMLAVAGTLIQKLTGNPMASPEVLGISSGAAFGVVMMLFMVPGDAFVWLLPAGSLGAAATLLIIMIAAGRGGFSTE 479
Cdd:PRK10577  405 LLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAGFGWLLAAALLGALAALALILLLARRGGFAPE 484

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 480 RMLLAGIALSTAFTTVIFLLLASGDPRMGGLLTWLSGSTYSVEPAQALRTALIAAGLLVLAPLCRRWLTILPLGGATARS 559
Cdd:PRK10577  485 RLLLTGIALSALFTALIQLLLASGDPRAAQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDTARA 564

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 560 VGIALTPARLSILLLAATLTAMATLTVGPLSFVGLMAPHMARMLGFRRALPQMVIAALLGGLLMVFADWCGRMLLFPYQI 639
Cdd:PRK10577  565 LGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRTLLFPYQI 644

                         650       660
                  ....*....|....*....|.
gi 1359192519 640 PAGLLATFIGAPYFVYLLRKQ 660
Cdd:PRK10577  645 PAGLLAALIGAPYFLWLLRRS 665
 
Name Accession Description Interval E-value
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
1-660 0e+00

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 681.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519   1 MSSGIRKLPLTLILLLLAAAGGLTIYNLAQQLPPAQWARALSAPDIDDVRQMLFHYSLLPRLTVSLLAGAGLGLVGVLFQ 80
Cdd:PRK10577    5 MSRRRARLPALLLALLLLLALALTLTQLSAALPLSQWLQALWGPDADDLEQLLLHYSRLPRLAIALLVGAALGLAGALLQ 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  81 QVLRNPLAEPSTLGVAAGAQLGLTIATLWVLPGGEFTRQLAAMVGAIVVGGLVFGVAWGKRMSPVTLILAGLVLGLYCGA 160
Cdd:PRK10577   85 QVLRNPLASPTTLGVAAGAQLALVLATLFAPALLALASQLAAFAGGLLAAALVFALAGGKRLSPLRLVLAGMVVSLYLGA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 161 VNSLLALFNYDQLQGMFLWGTGALNQQDWSAVQFLLPRLLVAGLLAALLLRPLTLLGLDDGVARNLGLGLSMARFCALGV 240
Cdd:PRK10577  165 LTTLLLLFNEQYLQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAALAL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 241 AIIFSAMLVSAVGVIGFIGLFAPLMAKMLGARRLAHRMMLAPLLGALLLWLTDQVMLGVTQVW-HEIPTGAATALFGAPL 319
Cdd:PRK10577  245 AVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARLPLSPLIGALLLLLTDQLVRLLAGVGgELLPTGAVTALIGAPL 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 320 LLWLLPRLRSAATPPPMNLGDKVPAERGNLPGWILVGGLVLLIGLALALMLGKNAGGWHWSLGVELDALLPWRWPRVLSA 399
Cdd:PRK10577  325 LLWLLPRLRSAQSAPAMSAGDRVAARRRRVLAWLLALGLLLLLALVVALSFGRDAHGWNWLSGQLLDALLPLRLPRLLAA 404

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 400 LAAGMMLAVAGTLIQKLTGNPMASPEVLGISSGAAFGVVMMLFMVPGDAFVWLLPAGSLGAAATLLIIMIAAGRGGFSTE 479
Cdd:PRK10577  405 LLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAGFGWLLAAALLGALAALALILLLARRGGFAPE 484

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 480 RMLLAGIALSTAFTTVIFLLLASGDPRMGGLLTWLSGSTYSVEPAQALRTALIAAGLLVLAPLCRRWLTILPLGGATARS 559
Cdd:PRK10577  485 RLLLTGIALSALFTALIQLLLASGDPRAAQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDTARA 564

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 560 VGIALTPARLSILLLAATLTAMATLTVGPLSFVGLMAPHMARMLGFRRALPQMVIAALLGGLLMVFADWCGRMLLFPYQI 639
Cdd:PRK10577  565 LGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRTLLFPYQI 644

                         650       660
                  ....*....|....*....|.
gi 1359192519 640 PAGLLATFIGAPYFVYLLRKQ 660
Cdd:PRK10577  645 PAGLLAALIGAPYFLWLLRRS 665
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 388-660 2.68e-74

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 241.13  E-value: 2.68e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 388 LLPWRWPRVLSALAAGMMLAVAGTLIQKLTGNPMASPEVLGISSGAAFGVVMMLFMVPGDAFVWLLPAGSLGA-AATLLI 466
Cdd:COG0609    31 VWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGAVLAIVLGGGLSALGLPLAAFLGAlLAALLV 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 467 IMIAAGRGGFSTERMLLAGIALSTAFTTVI-FLLLASGDPRMGGLLTWLSGSTYSVEPAQALRTALIAAGLLVLAPLCRR 545
Cdd:COG0609   111 YLLARRGGGLSPLRLVLAGVAVSALFSALTsLLLLLADPEQLRSIVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLAR 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 546 WLTILPLGGATARSVGIALTPARLSILLLAATLTAMATLTVGPLSFVGLMAPHMARMLGFRRALPQMVIAALLGGLLMVF 625
Cdd:COG0609   191 ALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLL 270

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1359192519 626 ADWCGRMLLFPYQIPAGLLATFIGAPYFVYLLRKQ 660
Cdd:COG0609   271 ADTLARTILAPAELPVGIVTALIGAPFFLYLLRRR 305
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 360-659 4.38e-60

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 203.53  E-value: 4.38e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 360 LLIGLALALMLGKN----AGGWHWSLG----VELDALLPWRWPRVLSALAAGMMLAVAGTLIQKLTGNPMASPEVLGISS 431
Cdd:pfam01032   2 LLLLILLSLFIGAVkispSDVFSALLGgddsLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 432 GAAFGVVMMLFMVPGDAFVWLLPAGSLGA-AATLLIIMIAAGRGGFSTERMLLAGIALSTAFTTVI-FLLLASGDPRMGG 509
Cdd:pfam01032  82 GAALGAVLAILLGGSLSLFALPLAAFIGAlLAALLVYFLSRGRGGASPLRLILAGIAVSALLSALTsLLLLLLNPEALQS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 510 LLTWLSGSTYSVEPAQALRTALIAAGLLVLAPLCRRWLTILPLGGATARSVGIALTPARLSILLLAATLTAMATLTVGPL 589
Cdd:pfam01032 162 ILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPI 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 590 SFVGLMAPHMARMLGFRRALPQMVIAALLGGLLMVFADWCGRMLLFPYQIPAGLLATFIGAPYFVYLLRK 659
Cdd:pfam01032 242 GFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 396-657 1.97e-49

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 173.13  E-value: 1.97e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 396 VLSALAAGMMLAVAGTLIQKLTGNPMASPEVLGISSGAAFGVVMMLFMVPGDAFVWLLPAGSLGAAATLLIIMIAAGRGG 475
Cdd:cd06550     1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 476 FSTERMLLAGIALSTAFTTVIFLLLASGDPRMGGLLTWLSGSTYSVEPAQALRTALIAAGLLVLAPLCRRWLTILPLGGA 555
Cdd:cd06550    81 LSPSKLILIGIVLSAFFSAGVILISLLSDDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDED 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 556 TARSVGIALTPARLSILLLAATLTAMATLTVGPLSFVGLMAPHMARMLGFRRALPQMVIAALLGGLLMVFADWCGRmLLF 635
Cdd:cd06550   161 LAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSR-TLL 239

                         250       260
                  ....*....|....*....|..
gi 1359192519 636 PYQIPAGLLATFIGAPYFVYLL 657
Cdd:cd06550   240 PSELPVGPVTALLGAPYFLYLL 261
 
Name Accession Description Interval E-value
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
1-660 0e+00

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 681.56  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519   1 MSSGIRKLPLTLILLLLAAAGGLTIYNLAQQLPPAQWARALSAPDIDDVRQMLFHYSLLPRLTVSLLAGAGLGLVGVLFQ 80
Cdd:PRK10577    5 MSRRRARLPALLLALLLLLALALTLTQLSAALPLSQWLQALWGPDADDLEQLLLHYSRLPRLAIALLVGAALGLAGALLQ 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  81 QVLRNPLAEPSTLGVAAGAQLGLTIATLWVLPGGEFTRQLAAMVGAIVVGGLVFGVAWGKRMSPVTLILAGLVLGLYCGA 160
Cdd:PRK10577   85 QVLRNPLASPTTLGVAAGAQLALVLATLFAPALLALASQLAAFAGGLLAAALVFALAGGKRLSPLRLVLAGMVVSLYLGA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 161 VNSLLALFNYDQLQGMFLWGTGALNQQDWSAVQFLLPRLLVAGLLAALLLRPLTLLGLDDGVARNLGLGLSMARFCALGV 240
Cdd:PRK10577  165 LTTLLLLFNEQYLQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAALAL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 241 AIIFSAMLVSAVGVIGFIGLFAPLMAKMLGARRLAHRMMLAPLLGALLLWLTDQVMLGVTQVW-HEIPTGAATALFGAPL 319
Cdd:PRK10577  245 AVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARLPLSPLIGALLLLLTDQLVRLLAGVGgELLPTGAVTALIGAPL 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 320 LLWLLPRLRSAATPPPMNLGDKVPAERGNLPGWILVGGLVLLIGLALALMLGKNAGGWHWSLGVELDALLPWRWPRVLSA 399
Cdd:PRK10577  325 LLWLLPRLRSAQSAPAMSAGDRVAARRRRVLAWLLALGLLLLLALVVALSFGRDAHGWNWLSGQLLDALLPLRLPRLLAA 404

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 400 LAAGMMLAVAGTLIQKLTGNPMASPEVLGISSGAAFGVVMMLFMVPGDAFVWLLPAGSLGAAATLLIIMIAAGRGGFSTE 479
Cdd:PRK10577  405 LLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAGFGWLLAAALLGALAALALILLLARRGGFAPE 484

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 480 RMLLAGIALSTAFTTVIFLLLASGDPRMGGLLTWLSGSTYSVEPAQALRTALIAAGLLVLAPLCRRWLTILPLGGATARS 559
Cdd:PRK10577  485 RLLLTGIALSALFTALIQLLLASGDPRAAQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDTARA 564

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 560 VGIALTPARLSILLLAATLTAMATLTVGPLSFVGLMAPHMARMLGFRRALPQMVIAALLGGLLMVFADWCGRMLLFPYQI 639
Cdd:PRK10577  565 LGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRTLLFPYQI 644

                         650       660
                  ....*....|....*....|.
gi 1359192519 640 PAGLLATFIGAPYFVYLLRKQ 660
Cdd:PRK10577  645 PAGLLAALIGAPYFLWLLRRS 665
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 388-660 2.68e-74

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 241.13  E-value: 2.68e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 388 LLPWRWPRVLSALAAGMMLAVAGTLIQKLTGNPMASPEVLGISSGAAFGVVMMLFMVPGDAFVWLLPAGSLGA-AATLLI 466
Cdd:COG0609    31 VWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGAVLAIVLGGGLSALGLPLAAFLGAlLAALLV 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 467 IMIAAGRGGFSTERMLLAGIALSTAFTTVI-FLLLASGDPRMGGLLTWLSGSTYSVEPAQALRTALIAAGLLVLAPLCRR 545
Cdd:COG0609   111 YLLARRGGGLSPLRLVLAGVAVSALFSALTsLLLLLADPEQLRSIVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLAR 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 546 WLTILPLGGATARSVGIALTPARLSILLLAATLTAMATLTVGPLSFVGLMAPHMARMLGFRRALPQMVIAALLGGLLMVF 625
Cdd:COG0609   191 ALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLL 270

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1359192519 626 ADWCGRMLLFPYQIPAGLLATFIGAPYFVYLLRKQ 660
Cdd:COG0609   271 ADTLARTILAPAELPVGIVTALIGAPFFLYLLRRR 305
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 360-659 4.38e-60

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 203.53  E-value: 4.38e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 360 LLIGLALALMLGKN----AGGWHWSLG----VELDALLPWRWPRVLSALAAGMMLAVAGTLIQKLTGNPMASPEVLGISS 431
Cdd:pfam01032   2 LLLLILLSLFIGAVkispSDVFSALLGgddsLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 432 GAAFGVVMMLFMVPGDAFVWLLPAGSLGA-AATLLIIMIAAGRGGFSTERMLLAGIALSTAFTTVI-FLLLASGDPRMGG 509
Cdd:pfam01032  82 GAALGAVLAILLGGSLSLFALPLAAFIGAlLAALLVYFLSRGRGGASPLRLILAGIAVSALLSALTsLLLLLLNPEALQS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 510 LLTWLSGSTYSVEPAQALRTALIAAGLLVLAPLCRRWLTILPLGGATARSVGIALTPARLSILLLAATLTAMATLTVGPL 589
Cdd:pfam01032 162 ILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPI 241

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 590 SFVGLMAPHMARMLGFRRALPQMVIAALLGGLLMVFADWCGRMLLFPYQIPAGLLATFIGAPYFVYLLRK 659
Cdd:pfam01032 242 GFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 391-657 2.17e-53

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 186.87  E-value: 2.17e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 391 WRWPRVLSALAAGMMLAVAGTLIQKLTGNPMASPEVLGISSGAAFGVVmmLFMVPGDAFVWLLPAGSL-GAAATLLIIMI 469
Cdd:COG4779    72 LRLPRALAALLVGAALGLSGAIFQSLTRNPLASPDIIGITAGASAGAV--AAIVVLGGSGLAVALGALaGGLATALLVYL 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 470 AAGRGGFSTERMLLAGIALSTAFTTVIFLLLASGDPR-MGGLLTWLSGSTYSVEPAQALRTALIAAGLLVLAPLCRRWLT 548
Cdd:COG4779   150 LAWRGGVSGYRLILVGIGVSAMLTAVNSYLLTRADLEdAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLR 229

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 549 ILPLGGATARSVGIALTPARLSILLLAATLTAMATLTVGPLSFVGLMAPHMARMLgFRRALPQMVIAALLGGLLMVFADW 628
Cdd:COG4779   230 LLELGDDTAAALGVRVERTRLLLLLVAVALAAVATAAAGPIAFVALAAPQIARRL-TRSPGPPLLPSALVGALLLLAADL 308

                         250       260
                  ....*....|....*....|....*....
gi 1359192519 629 CGRMLLFPYQIPAGLLATFIGAPYFVYLL 657
Cdd:COG4779   309 VAQHLLAPVQLPVGVVTGALGGPYLLWLL 337
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 396-657 1.97e-49

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 173.13  E-value: 1.97e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 396 VLSALAAGMMLAVAGTLIQKLTGNPMASPEVLGISSGAAFGVVMMLFMVPGDAFVWLLPAGSLGAAATLLIIMIAAGRGG 475
Cdd:cd06550     1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 476 FSTERMLLAGIALSTAFTTVIFLLLASGDPRMGGLLTWLSGSTYSVEPAQALRTALIAAGLLVLAPLCRRWLTILPLGGA 555
Cdd:cd06550    81 LSPSKLILIGIVLSAFFSAGVILISLLSDDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDED 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 556 TARSVGIALTPARLSILLLAATLTAMATLTVGPLSFVGLMAPHMARMLGFRRALPQMVIAALLGGLLMVFADWCGRmLLF 635
Cdd:cd06550   161 LAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSR-TLL 239

                         250       260
                  ....*....|....*....|..
gi 1359192519 636 PYQIPAGLLATFIGAPYFVYLL 657
Cdd:cd06550   240 PSELPVGPVTALLGAPYFLYLL 261
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 32-273 3.27e-42

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 154.84  E-value: 3.27e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  32 LPPAQWARALSAPDIDDVRQMLFHYSLLPRLTVSLLAGAGLGLVGVLFQQVLRNPLAEPSTLGVAAGAQLGLTIATLWVL 111
Cdd:COG0609     9 ISLSDVLRALLGPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGAVLAIVLGG 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 112 PGGEFTRQLAAMVGAIVVGGLVFGVAW-GKRMSPVTLILAGLVLGLYCGAVNSLLALF-NYDQLQGMFLWGTGALNQQDW 189
Cdd:COG0609    89 GLSALGLPLAAFLGALLAALLVYLLARrGGGLSPLRLVLAGVAVSALFSALTSLLLLLaDPEQLRSIVFWLMGSLAGASW 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 190 SAVQFLLPRLLVAGLLAALLLRPLTLLGLDDGVARNLGLGLSMARFCALGVAIIFSAMLVSAVGVIGFIGLFAPLMAKML 269
Cdd:COG0609   169 DDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLVVPHIARLL 248


                  ....
gi 1359192519 270 GARR 273
Cdd:COG0609   249 VGPD 252
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 32-317 5.84e-37

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 140.35  E-value: 5.84e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  32 LPPAQWARALSAPDiDDVRQMLFHYSLLPRLTVSLLAGAGLGLVGVLFQQVLRNPLAEPSTLGVAAGAQLGLTIATLWVL 111
Cdd:pfam01032  17 ISPSDVFSALLGGD-DSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGAALGAVLAILLGG 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 112 PGGEFTRQLAAMVGAIVVGGLVFGVA-WGKRMSPVTLILAGLVLGLYCGAVNSLLALF-NYDQLQGMFLWGTGALNQQDW 189
Cdd:pfam01032  96 SLSLFALPLAAFIGALLAALLVYFLSrGRGGASPLRLILAGIAVSALLSALTSLLLLLlNPEALQSILFWLMGSLSGANW 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 190 SAVQFLLPRLLVAGLLAALLLRPLTLLGLDDGVARNLGLGLSMARFCALGVAIIFSAMLVSAVGVIGFIGLFAPLMAKML 269
Cdd:pfam01032 176 SDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGFVGLIVPHIARLL 255

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1359192519 270 GARRLAHRMMLAPLLGALLLWLTDQVMLGVTQVWhEIPTGAATALFGA 317
Cdd:pfam01032 256 VGANHRRLLPLSALLGALLLLLADILARTILSPY-ELPVGIVTALIGA 302
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
358-657 4.08e-36

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 138.26  E-value: 4.08e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 358 LVLLIGLALALMLGKNAGGWH-----WSLGVELD-ALLPWRWPRVLSALAAGMMLAVAGTLIQKLTGNPMASPEVLGISS 431
Cdd:PRK09777   11 LALAGCALLSLRMGVIPLPWRalltdWQAGDEHYyVLMEYRLPRLLLALFVGAALAVSGVLVQGIVRNPLASPDILGVNH 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 432 GAAFGVVMMLFMVPGDAFVWLLPAGSLGAAATLLIIMIAAGRGgfSTERMLLAGIALSTAFTTVIFLLLASGDPRMGGLL 511
Cdd:PRK09777   91 AASLASVGALLLFPSLPVMWLPLLAFIGGMAGLILLKMLAGTH--QPMKLALTGVALSALWASLTDYLMLSRPQDINNAL 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 512 TWLSGSTYSVEPAQALRTALIAAGLLVLAPLCRRWLTILPLGGATARSVGIALTPARLSILLLAATLTAMATLTVGPLSF 591
Cdd:PRK09777  169 LWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVALTATGVAACGPISF 248

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1359192519 592 VGLMAPHMARMLGFRRALPQMVIAALLGGLLMVFADWCGRMLLFPYQIPAGLLATFIGAPYFVYLL 657
Cdd:PRK09777  249 IGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFFWLL 314
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 352-660 8.42e-34

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 131.90  E-value: 8.42e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 352 WILVGGLVLLIGLALALMLGKNA-GGWHWSLGVELDALLPWRWPRVLSALAAGMMLAVAGTLIQKLTGNPMASPEVLGIS 430
Cdd:COG4139    14 WLLLLLLLLLLLFVLSLCAGEVWiPPTQWLSEAWQLFVWQLRLPRTLAAVLVGASLAVSGAVMQALFENPLAEPGLLGIS 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 431 SGAAFGVVMMLFMVPGDAFVWLLPAGSLGAAATLLIIMIAAGRGGFSTERMLLAGIAL---STAFTTVIFLLLASGDPRM 507
Cdd:COG4139    94 NGAGVGLVLVVLLGGGLLPPWLLSLAAIAGALLVTLLLLAFARRRLSNARLLLIGVALgiiCSAIMTWAVYFSSSLDLRQ 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 508 ggLLTWLSGSTYSVEPAQaLRTALIAAGLLVLAPLCRRWLTILPLGGATARSVGIALTPARLSILLLAATLTAMATLTVG 587
Cdd:COG4139   174 --LMYWMMGSFGGVDWRQ-LWLLLALLPVLLWLCLQGKPLNLLLLGENQARQLGLSVHRWRNLLVLATGLLVGVSVALAG 250

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1359192519 588 PLSFVGLMAPHMARMLGF---RRALPqmvIAALLGGLLMVFADWCGRMLLFPYQIPAGLLATFIGAPYFVYLLRKQ 660
Cdd:COG4139   251 PIGFVGLVVPHLLRLLGTtdhRFLLP---ACALAGAALLLLADIIARLALSSAELPIGVVTATLGAPVFIWLLLRR 323
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
392-661 8.60e-33

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 129.04  E-value: 8.60e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 392 RWPRVLSALAAGMMLAVAGTLIQKLTGNPMASPEVLGISSGAAFGvvmmlfMVPGDAFVWLLPAG-------SLGAAATL 464
Cdd:PRK11228   51 RLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALA------MALTSALSPTPFAGyslafiaACGGGLSW 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 465 LIIMIAAG--RGGFSTERMLLAGIALSTAFTTVIFLLLASGDPRMGGLLTWLSGSTYSVEPAQALRTALIAAGLLVLAPL 542
Cdd:PRK11228  125 LLVMTAGGgwRHTHDRNRLILAGIALSALCMALTRITLLLAEDHAYGIFYWLAGGVSHARWQEVWQLLPFVVTAVPVVLL 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 543 CRRWLTILPLGGATARSVGIALTPARLSILLLAATLTAMATLTVGPLSFVGLMAPHMARM-LGF--RRALPqmvIAALLG 619
Cdd:PRK11228  205 LANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFwIGYdqRNVLP---MSMLLG 281

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1359192519 620 GLLMVFADWCGRMLLFPYQIPAGLLATFIGAPYFVYLLRKQT 661
Cdd:PRK11228  282 ATLMLLADLLARALAFPGELPAGAVLALIGAPCFVWLARRRG 323
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 352-660 1.07e-32

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 128.92  E-value: 1.07e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 352 WILVGGLVLLIGLALALMLGKN-AGGWHWSLGVELDALLPWRWPRVLSALAAGMMLAVAGTLIQKLTGNPMASPEVLGIS 430
Cdd:PRK03784   17 WLLGLSVLLLLALLLSLCAGEQwISPGDWLSPRGELFVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVS 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 431 SGAAFGVVMMLFMVPGDAFVWLLPAGS-LGAAATLLIIMIAAGRGGFSTERMLLAGIAL---STAFTTVIFLLLASGDPR 506
Cdd:PRK03784   97 NGAGVALVAAVLLGQGLLPPWALSLCAiAGALLITLILLRFARRHRLSTSRLLLAGVALgiiCSALMTWAVYFSTSLDLR 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 507 MggLLTWLSGSTYSVEPAQALrtaLIAAGLLVLAPLCRRW--LTILPLGGATARSVGIALTPARLSILLLAATLTAMATL 584
Cdd:PRK03784  177 Q--LMYWMMGGFGGVDWRQSW---LMLALLPVLIWLCCQGrpLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVA 251

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1359192519 585 TVGPLSFVGLMAPHMARMLGF---RRALPqmvIAALLGGLLMVFADWCGRMLLFPYQIPAGLLATFIGAPYFVYLLRKQ 660
Cdd:PRK03784  252 LAGAIGFIGLVIPHILRLCGLtdhRVLLP---GCALAGASLLLLADIVARLALASAELPIGVVTATLGAPVFIWLLLRS 327
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
354-661 2.45e-30

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 122.13  E-value: 2.45e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 354 LVGGLVLLIGLALALMLGKNAGGWHWSLGVELDALL------------PWRWPRVLSALAAGMMLAVAGTLIQKLTGNPM 421
Cdd:PRK10440    9 LITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMgdaprsmtmvvtEWRLPRVLMALLIGAALGVSGAIFQSLMRNPL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 422 ASPEVLGISSGAAFGVVMMLFMVPGDAFVWLLPAGSlGAAATLLIIMIAAGRGGFSTERMLLAGIALS---TAFTTVIfL 498
Cdd:PRK10440   89 GSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMA-GGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRamlVAFNTWL-L 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 499 LLASGDPRMGGLLtWLSGSTYSVEPAQALRTALIAAGLLVLAPLCRRWLTILPLGGATARSVGIALTPARLSILLLAATL 578
Cdd:PRK10440  167 LKASLETALTAGL-WNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLMLVAVVL 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 579 TAMATLTVGPLSFVGLMAPHMARMLGfRRALPQMVIAALLGGLLMVFADWCGRMLLFPYQIPAGLLATFIGAPYFVYLLR 658
Cdd:PRK10440  246 TAAATALAGPISFIALVAPHIARRLS-GTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLI 324


                  ...
gi 1359192519 659 KQT 661
Cdd:PRK10440  325 QES 327
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 64-317 8.29e-28

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 112.65  E-value: 8.29e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  64 VSLLAGAGLGLVGVLFQQVLRNPLAEPSTLGVAAGAQLGLTIATLWVLPGGEFTRQLAAMVGAIVVGGLVFGVAWGKRMS 143
Cdd:cd06550     3 AALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRGGLS 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 144 PVTLILAGLVLGLYCGAVNSLLALFNYDQLQGMFLWGTGALNQQDWSAVQFLLPRLLVAGLLAALLLRPLTLLGLDDGVA 223
Cdd:cd06550    83 PSKLILIGIVLSAFFSAGVILISLLSDDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDEDLA 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 224 RNLGLGLSMARFCALGVAIIFSAMLVSAVGVIGFIGLFAPLMAKMLGARRLAHRMMLAPLLGALLLWLTDqvMLGVTQVW 303
Cdd:cd06550   163 KSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGD--LLSRTLLP 240

                         250
                  ....*....|....
gi 1359192519 304 HEIPTGAATALFGA 317
Cdd:cd06550   241 SELPVGPVTALLGA 254
btuC PRK09535
cobalamin ABC transporter permease BtuC;
392-659 2.66e-27

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 114.08  E-value: 2.66e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 392 RWPRVLSALAAGMMLAVAGTLIQKLTGNPMASPEVLGISSGAAFGVVMML-------FMVPGDAFvwllpAGSLGAAATL 464
Cdd:PRK09535   95 RLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIvlplavpFGLQAAAF-----AGALVAAFGV 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 465 LIIMIAAGRGGFSTerMLLAGIALSTAFTTVI-FLLLASGD---PRMGGLLTWLSGSTYSVEPAQALRTALIAAGLLVLA 540
Cdd:PRK09535  170 YAIATENGRTPVAT--LLLAGVAVQTFLGAVIsYLLLHSGEslrRAVYWLMGHLHGSTWSDVEVALPVVVVGFVVLLAYA 247

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 541 plcrRWLTILPLGGATARSVGIALTPARLSILLLAATLTAMATLTVGPLSFVGLMAPHMARML---GFRRALPqmvIAAL 617
Cdd:PRK09535  248 ----RDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLvgpDHRILLP---TSAL 320

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1359192519 618 LGGLLMVFADWCGRmlLFPYQIPAGLLATFIGAPYFVYLLRK 659
Cdd:PRK09535  321 AGASFLVATDTVAR--SGPAEVPVGIVTAALGAPFFLYLLRT 360
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 59-269 2.09e-26

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 110.98  E-value: 2.09e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  59 LPRLTVSLLAGAGLGLVGVLFQQVLRNPLAEPSTLGVAAGAQLGLTIATLwVLPGGEFTRQLAAMVGAIVVGGLVFGVAW 138
Cdd:COG4779    74 LPRALAALLVGAALGLSGAIFQSLTRNPLASPDIIGITAGASAGAVAAIV-VLGGSGLAVALGALAGGLATALLVYLLAW 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 139 GKRMSPVTLILAGLVLGLYCGAVNS-LLALFNYDQLQGMFLWGTGALNQQDWSAVQFLLPRLLVAGLLAALLLRPLTLLG 217
Cdd:COG4779   153 RGGVSGYRLILVGIGVSAMLTAVNSyLLTRADLEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLE 232

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1359192519 218 LDDGVARNLGLGLSMARFCALGVAIIFSAMLVSAVGVIGFIGLFAPLMAKML 269
Cdd:COG4779   233 LGDDTAAALGVRVERTRLLLLLVAVALAAVATAAAGPIAFVALAAPQIARRL 284
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
350-660 2.43e-22

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 98.63  E-value: 2.43e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 350 PGWILVGGLVLLIGLALALMLGKNAggwhWSLGVELDAL------------LPWRWPRVLSALAAGMMLAVAGTLIQKLT 417
Cdd:PRK10441   10 AIAVPGLLLLLIIATALSLLIGAKS----LPASVVLEALsgtcqsadctivLDARLPRTLAGLLAGGALGLAGALMQTLT 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 418 GNPMASPEVLGISSGAAFGVVMMLFMVPGDAFVWLLPAGSLGAAATLLIIMIAAGRGG--FSTERMLLAGIALST---AF 492
Cdd:PRK10441   86 RNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGgqLSPVRLTLAGVALAAvleGL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 493 TTVIFLLlasgDPRMGGLLTWLSGSTYSVEPAQALRTALIAAGL-LVLAPLCRRWLTILPLGGATARSVGIALTPARLSI 571
Cdd:PRK10441  166 TSGIALL----NPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIaGATALLLSRALNSLSLGSDTATALGSRVARTQLIG 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 572 LLLAATLTAMATLTVGPLSFVGLMAPHMARMLGFRRALPQMVIAALLGGLLMVFADWCGRmLLFPYQIPAGLLATFIGAP 651
Cdd:PRK10441  242 LLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGR-LLVPGELRVSVVSAFIGAP 320


                  ....*....
gi 1359192519 652 YFVYLLRKQ 660
Cdd:PRK10441  321 VLIFLVRRK 329
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
32-317 2.05e-19

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 89.75  E-value: 2.05e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  32 LPPAQWARALSAPDIDDVRQMLFHYSLLPRLTVSLLAGAGLGLVGVLFQQVLRNPLAEPSTLGVAAGAQLGLTIATLWV- 110
Cdd:PRK11228   25 ISAADALNALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALTSALSp 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 111 LPGGEFTRQLAAMVGAIVVGGLVF--GVAWGKRMSPVTLILAGLVLGLYCGAVNSLLALFNYDQLQGMFLWGTGALNQQD 188
Cdd:PRK11228  105 TPFAGYSLAFIAACGGGLSWLLVMtaGGGWRHTHDRNRLILAGIALSALCMALTRITLLLAEDHAYGIFYWLAGGVSHAR 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 189 WSAVQFLLPRLLVAGLLAALLLRPLTLLGLDDGVARNLGLGLSMARFCALGVAIIFSAMLVSAVGVIGFIGLFAPLMAKM 268
Cdd:PRK11228  185 WQEVWQLLPFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARF 264

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1359192519 269 LGARRLAHRMMLAPLLGALLLWLTDQVMLGVTqVWHEIPTGAATALFGA 317
Cdd:PRK11228  265 WIGYDQRNVLPMSMLLGATLMLLADLLARALA-FPGELPAGAVLALIGA 312
btuC PRK09535
cobalamin ABC transporter permease BtuC;
45-269 1.17e-17

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 85.19  E-value: 1.17e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  45 DIDDVRQMLFHYSLLPRLTVSLLAGAGLGLVGVLFQQVLRNPLAEPSTLGVAAGAQLGL--TIATLWVLPggeFTRQLAA 122
Cdd:PRK09535   82 AVPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAvaAIVLPLAVP---FGLQAAA 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 123 MVGAIVVGGLVFGVAWGKRMSPV-TLILAGLVLGLYCGAVNSLLALFNYDQLQGMFLWGTGALNQQDWSAVQFLLPRLLV 201
Cdd:PRK09535  159 FAGALVAAFGVYAIATENGRTPVaTLLLAGVAVQTFLGAVISYLLLHSGESLRRAVYWLMGHLHGSTWSDVEVALPVVVV 238

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1359192519 202 AGLLAALLLRPLTLLGLDDGVARNLGLGLSMARFCALGVAIIFSAMLVSAVGVIGFIGLFAPLMAKML 269
Cdd:PRK09535  239 GFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLL 306
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 30-270 2.36e-16

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 80.67  E-value: 2.36e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  30 QQLPPAQWARALSapdiddvrQMLFHYSLLPRLTVSLLAGAGLGLVGVLFQQVLRNPLAEPSTLGVAAGAQLGLTIATL- 108
Cdd:COG4139    35 VWIPPTQWLSEAW--------QLFVWQLRLPRTLAAVLVGASLAVSGAVMQALFENPLAEPGLLGISNGAGVGLVLVVLl 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 109 --WVLPGGEFTrqLAAMVGAIVVGGLVFGVAwGKRMSPVTLILAGLVLGLYCGAVNSLLALFNYD-QLQGMFLWGTGALN 185
Cdd:COG4139   107 ggGLLPPWLLS--LAAIAGALLVTLLLLAFA-RRRLSNARLLLIGVALGIICSAIMTWAVYFSSSlDLRQLMYWMMGSFG 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 186 QQDWSAvQFLLPRLLVAGLLAALLLRPLTLLGLDDGVARNLGLGLSMARFCALGVAIIFSAMLVSAVGVIGFIGLFAPLM 265
Cdd:COG4139   184 GVDWRQ-LWLLLALLPVLLWLCLQGKPLNLLLLGENQARQLGLSVHRWRNLLVLATGLLVGVSVALAGPIGFVGLVVPHL 262


                  ....*
gi 1359192519 266 AKMLG 270
Cdd:COG4139   263 LRLLG 267
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
59-270 2.64e-15

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 77.44  E-value: 2.64e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  59 LPRLTVSLLAGAGLGLVGVLFQQVLRNPLAEPSTLGVAAGAQLGLTIATLWVLPGGEFTRQLAAMVGAIVVGGLVF--GV 136
Cdd:PRK10441   61 LPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAftGS 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 137 AWGKRMSPVTLILAGLVLGLYCGAVNSLLALFNYDQLQGMFLWGTGALNQQDWSAVQFLLPRLLVAGLLAALLLRPLTLL 216
Cdd:PRK10441  141 QGGGQLSPVRLTLAGVALAAVLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSL 220

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1359192519 217 GLDDGVARNLGLGLSMARFCALGVAIIFSAMLVSAVGVIGFIGLFAPLMAKMLG 270
Cdd:PRK10441  221 SLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLV 274
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
34-317 1.13e-14

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 75.47  E-value: 1.13e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  34 PAQWARALSAPDIDDVRQMLFHYSLLPRLTVSLLAGAGLGLVGVLFQQVLRNPLAEPSTLGVAAGAQLgLTIATLWVLPG 113
Cdd:PRK09777   27 PLPWRALLTDWQAGDEHYYVLMEYRLPRLLLALFVGAALAVSGVLVQGIVRNPLASPDILGVNHAASL-ASVGALLLFPS 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 114 GEFT-RQLAAMVGAIVVGGLVFGVAwgKRMSPVTLILAGLVLGLYCGAVNSLLALFNYDQLQGMFLWGTGALNQQDWSAV 192
Cdd:PRK09777  106 LPVMwLPLLAFIGGMAGLILLKMLA--GTHQPMKLALTGVALSALWASLTDYLMLSRPQDINNALLWLTGSLWGRDWSFV 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 193 QFLLPRLLVAGLLAALLLRPLTLLGLDDGVARNLGLGLSMARFCALGVAIIFSAMLVSAVGVIGFIGLFAP-LMAKMLGA 271
Cdd:PRK09777  184 KVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVALTATGVAACGPISFIGLVVPhLMRSLVGG 263

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1359192519 272 RRlaHRMMLAPLLGALLLWLTDQVMLGVTQVWHEIPTGAATALFGA 317
Cdd:PRK09777  264 RH--RRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGA 307
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
59-273 1.05e-13

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 72.82  E-value: 1.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  59 LPRLTVSLLAGAGLGLVGVLFQQVLRNPLAEPSTLGVAAGAQLGLTIATLwVLPGGEFTRQLAAMVGAIVVGGLVFGVAW 138
Cdd:PRK10440   60 LPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMV-LFGQDLTAIALAAMAGGIVTSLLVWLLAW 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 139 GKRMSPVTLILAGLVLGLYCGAVNSLLAL-FNYDQLQGMFLWGTGALNQQDWSAVQFLLPRLLVAGLLAALLLRPLTLLG 217
Cdd:PRK10440  139 RNGIDTFRLIIIGIGVRAMLVAFNTWLLLkASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLE 218

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1359192519 218 LDDGVARNLGLGLSMARFCALGVAIIFSAMLVSAVGVIGFIGLFAPLMAKML-GARR 273
Cdd:PRK10440  219 MGDDTACALGVSVERSRLLLMLVAVVLTAAATALAGPISFIALVAPHIARRLsGTAR 275
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 30-270 9.34e-12

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 66.90  E-value: 9.34e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  30 QQLPPAQWARALSAPDIDDVRqmlfhyslLPRLTVSLLAGAGLGLVGVLFQQVLRNPLAEPSTLGVAAGAQLGLTIATLW 109
Cdd:PRK03784   38 QWISPGDWLSPRGELFVWQLR--------LPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLL 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 110 ---VLPGGEFTrqLAAMVGAIVVGGLVFGVAWGKRMSPVTLILAGLVLGLYCGAVNSLLALFNYDQ-LQGMFLWGTGALN 185
Cdd:PRK03784  110 gqgLLPPWALS--LCAIAGALLITLILLRFARRHRLSTSRLLLAGVALGIICSALMTWAVYFSTSLdLRQLMYWMMGGFG 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519 186 QQDW---SAVQFLLPrllvAGLLAALLLRPLTLLGLDDGVARNLGLGLSMARFCALGVAIIFSAMLVSAVGVIGFIGLFA 262
Cdd:PRK03784  188 GVDWrqsWLMLALLP----VLIWLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVI 263


                  ....*...
gi 1359192519 263 PLMAKMLG 270
Cdd:PRK03784  264 PHILRLCG 271
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
 111-628 1.75e-04

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 44.86  E-value: 1.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  111 LPGGEFTRQLAAM-----VGAIVVGGLVFGVAWGKRMSPVTLILAGLVLGLYCGAVNSLLALFNYDQLQGMFLWGTGALN 185
Cdd:COG3321    863 LPTYPFQREDAAAallaaALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAAL 942

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  186 QQDWSAVQFLLPRLLVAGLLAALLLRPLTLLGLDDGVARNLGLGLSMARFCALGVAIIFSAMLVSAVGVIGFIGLFAPLM 265
Cdd:COG3321    943 LALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAALL 1022

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  266 AKMLGARRLAHRMMLAPLLGALLLWLTDQVMLGVTQVWHEIPTGAATALFGAPLLLWLLPRLRSAATPPPMNLGDKVPAE 345
Cdd:COG3321   1023 ALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALALAAL 1102

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  346 RGnlpgwiLVGGLVLLIGLALALMLGKNAGGWHWSLGVELDALLPWRWPRVLSALAAGMMLAVAGTLIQKLTGNPMASPE 425
Cdd:COG3321   1103 AA------ALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLA 1176

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  426 VLGISSGAAFGVVMMLFMVPGDAFVWLLPAGSLGAAATLLIIMIAAGRGGFSTERMLLAGIALSTAFTTVIFLLLASGDP 505
Cdd:COG3321   1177 LALALAAALAAALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAAAAALL 1256

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  506 RMGGLLTWLSGSTYSVEPAQALRTALIAAGLLVLAPLCRRWLTILPLGGATARSVGIALTPARLSILLLAATLTAMATLT 585
Cdd:COG3321   1257 AALAALALLAAAAGLAALAAAAAAAAAALALAAAAAAAAAALAALLAAAAAAAAAAAAAAAAAALAAALLAAALAALAAA 1336

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 1359192519  586 VGPLSFVGLMAPHMARMLGFRRALPQMVIAALLGGLLMVFADW 628
Cdd:COG3321   1337 VAAALALAAAAAAAAAAAAAAAAAAALAAAAGAAAAAAALALA 1379
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
 32-547 2.71e-03

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 41.01  E-value: 2.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519   32 LPPAQWAR---ALSAPDIDDVRQMLFHYSLLPRLTVSLLAGAGLGLVGVLFQQVLRNPLAEPSTLGVAAGAQLGLTIATL 108
Cdd:COG3321    863 LPTYPFQRedaAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAAL 942

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  109 WVLPGGEFTRQLAAMVGAIVVGGLVFGVAWGKRMSPVTLILAGLVLGLYCGAVNSLLALFNYDQLQGMFLWGTGALNQQD 188
Cdd:COG3321    943 LALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAALL 1022

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  189 WSAVQFLLPRLLVAGLLAALLLRPLTLLGLDDGVARNLGLGLSMARFCALGVAIIFSAMLVSAVGVIGFIGLFAPLMAKM 268
Cdd:COG3321   1023 ALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALALAAL 1102

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  269 LGARRLAHRMMLAPLLGALLLWLTDQVMLGVTQVWHEIPTGAATALFGAPLLLWLLPRLRSAATPPPMNLGDkVPAERGN 348
Cdd:COG3321   1103 AAALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALL-LALALAL 1181

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  349 LPGWILVGGLVLLIGLALALMLGKNAGGWHWSLGVELDALLPWRWPRVLSALAAGMMLAVAGTLIQKLTGNPMASPEVLG 428
Cdd:COG3321   1182 AAALAAALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAAAAALLAALAA 1261

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1359192519  429 ISSGAAFGVVMMLFMVPGDAFVWLLPAGSLGAAATLLIIMIAAGRGGFSTERMLLAGIALSTAFTTVIFLLLASGDPRMG 508
Cdd:COG3321   1262 LALLAAAAGLAALAAAAAAAAAALALAAAAAAAAAALAALLAAAAAAAAAAAAAAAAAALAAALLAAALAALAAAVAAAL 1341

                          490       500       510
                   ....*....|....*....|....*....|....*....
gi 1359192519  509 GLLTWLSGSTYSVEPAQALRTALIAAGLLVLAPLCRRWL 547
Cdd:COG3321   1342 ALAAAAAAAAAAAAAAAAAAALAAAAGAAAAAAALALAA 1380
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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