|
Name |
Accession |
Description |
Interval |
E-value |
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
14-343 |
5.45e-77 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 242.56 E-value: 5.45e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 14 DSVEDQVERYKQVLDVMPAGVILLDTQGVVREANPEAQRLLQVP------------LAGEKWYSVIQSAFAPREDDGHEI 81
Cdd:COG5000 83 EELEERRRYLETILENLPAGVIVLDADGRITLANPAAERLLGIPleeligkpleelLPELDLAELLREALERGWQEEIEL 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 82 SLRNGRKVRLAISA-SATGQLILITDLTEtrLLQSrisdlQRLSSLGRMVASLAHQVRTPLSSAMLYASNLG---APNLP 157
Cdd:COG5000 163 TRDGRRTLLVRASPlRDDGYVIVFDDITE--LLRA-----ERLAAWGELARRIAHEIKNPLTPIQLSAERLRrklADKLE 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 158 N--ATRERFQSKLMDRLHDLEKQVNDMLLFAKGGDNKvIQPFTVTDLVSEFVPMVETALKNSAIDYHQEVEQEGTVVLGN 235
Cdd:COG5000 236 EdrEDLERALDTIIRQVDRLKRIVDEFLDFARLPEPQ-LEPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPEVLAD 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 236 ANAIASALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQGTGLGLAVVQMVCRA 315
Cdd:COG5000 315 RDQLEQVLINLLKNAIEAIEEGGEIEVSTRREDGRVRIEVSDNGPGIPEEVLERIFEPFFTTKPKGTGLGLAIVKKIVEE 394
|
330 340
....*....|....*....|....*...
gi 1447635730 316 HDGRLELISEEGEGACFTMCIPLERHAP 343
Cdd:COG5000 395 HGGTIELESRPGGGTTFTIRLPLAEEAE 422
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
21-345 |
1.17e-62 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 203.92 E-value: 1.17e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 21 ERYKQVLDVMPAGVILLDTQGVVREANPEAQRLLQVP---LAGEKWYSVIQSAFAPRED-----------DGHEISLR-- 84
Cdd:COG3852 7 ELLRAILDSLPDAVIVLDADGRITYVNPAAERLLGLSaeeLLGRPLAELFPEDSPLRELleralaegqpvTEREVTLRrk 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 85 NGRKVRLAISASA-------TGQLILITDLTETRLLQSRISDLQRLSSLGRMVASLAHQVRTPLSSAMLYASNLGAPNLP 157
Cdd:COG3852 87 DGEERPVDVSVSPlrdaegeGGVLLVLRDITERKRLERELRRAEKLAAVGELAAGLAHEIRNPLTGIRGAAQLLERELPD 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 158 NATRERFQskLM----DRLHDLekqVNDMLLFAKGGDNKViQPFTVTDLVSEFVPMVETALKNSaIDYHQEVEQEGTVVL 233
Cdd:COG3852 167 DELREYTQ--LIieeaDRLNNL---VDRLLSFSRPRPPER-EPVNLHEVLERVLELLRAEAPKN-IRIVRDYDPSLPEVL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 234 GNANAIASALSNLVMNAIQ----------IAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQGTG 303
Cdd:COG3852 240 GDPDQLIQVLLNLVRNAAEampeggtitiRTRVERQVTLGGLRPRLYVRIEVIDNGPGIPEEILDRIFEPFFTTKEKGTG 319
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1447635730 304 LGLAVVQMVCRAHDGRLELISEEGEGACFTMCIPLERHAPSS 345
Cdd:COG3852 320 LGLAIVQKIVEQHGGTIEVESEPGKGTTFRIYLPLEQAEEEP 361
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
17-338 |
7.00e-53 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 178.45 E-value: 7.00e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 17 EDQVERYKQVLDVMPAGVILLDTQGVVREANPEAQRLLQVPLAGEKWYSVIQSAFAPREDDGHEISLRNGRKVRLAISAS 96
Cdd:COG4191 33 LALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLEALLLLLLAALDAEENAELEEL 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 97 ATGQLILITDLTETRLLQSRISDLQRLSSLGRMVASLAHQVRTPLSSAMLYASNLGApnlpNATRERFQSKLMDRLHDLE 176
Cdd:COG4191 113 ERDITELERAEEELRELQEQLVQSEKLAALGELAAGIAHEINNPLAAILGNAELLRR----RLEDEPDPEELREALERIL 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 177 KQ-------VNDMLLFAKGGDNKvIQPFTVTDLVSEFVPMVETALKNSAIDYHQEVEQEGTVVLGNANAIASALSNLVMN 249
Cdd:COG4191 189 EGaeraaeiVRSLRAFSRRDEEE-REPVDLNELIDEALELLRPRLKARGIEVELDLPPDLPPVLGDPGQLEQVLLNLLIN 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 250 AIQ-IAGKAS-QIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRS--QGTGLGLAVVQMVCRAHDGRLELISE 325
Cdd:COG4191 268 AIDaMEEGEGgRITISTRREGDYVVISVRDNGPGIPPEVLERIFEPFFTTKPvgKGTGLGLSISYGIVEKHGGRIEVESE 347
|
330
....*....|...
gi 1447635730 326 EGEGACFTMCIPL 338
Cdd:COG4191 348 PGGGTTFTITLPL 360
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
35-339 |
1.89e-51 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 173.94 E-value: 1.89e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 35 ILLDTQGVVREANPEAQRLLQVPLAGEKWYSVIQSAFAPREDDGHEISLRNGRKVRLAISASATGQLILITDLTETRLLQ 114
Cdd:COG0642 18 LLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 115 SRISDLQRLS-SLGRMVASLAHQVRTPLSSAMLYASNLGapNLPNATRERFQSKLMDRLHDLEKQVNDMLLFAK---GGD 190
Cdd:COG0642 98 ALLLLLEEANeAKSRFLANVSHELRTPLTAIRGYLELLL--EELDEEQREYLETILRSADRLLRLINDLLDLSRleaGKL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 191 NKVIQPFTVTDLVSEFVPMVETALKNSAIDYHQEVEQEGTVVLGNANAIASALSNLVMNAIQIAGKASQIDVFFRPVNGE 270
Cdd:COG0642 176 ELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTVSVRREGDR 255
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1447635730 271 LKISVQDSGPGVPAALQSKIMEPFFTT----RSQGTGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIPLE 339
Cdd:COG0642 256 VRISVEDTGPGIPPEDLERIFEPFFRTdpsrRGGGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTVTLPLA 328
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
113-340 |
6.92e-49 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 164.31 E-value: 6.92e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 113 LQSRISDLQRLSSL-GRMVASLAHQVRTPLSSAMLYASNLG-APNLPNATRERFQSKLMDRLHDLEKQVNDMLLFAKGGD 190
Cdd:COG2205 2 LEEALEELEELERLkSEFLANVSHELRTPLTSILGAAELLLdEEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLES 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 191 NKV---IQPFTVTDLVSEFVPMVETALKNSAIDYHQEVEQEGTVVLGNANAIASALSNLVMNAIQIAGKASQIDVFFRPV 267
Cdd:COG2205 82 GKLsleLEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARRE 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1447635730 268 NGELKISVQDSGPGVPAALQSKIMEPFF----TTRSQGTGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIPLER 340
Cdd:COG2205 162 GDGVRISVSDNGPGIPEEELERIFERFYrgdnSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLPLAE 238
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
26-340 |
1.87e-46 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 166.68 E-value: 1.87e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 26 VLDVMPAGVILLDTQGVVREANPEAQRLLQVP---LAGEKWYSViqsaFAPredDGHEIS-----LRNGRKVR------- 90
Cdd:PRK11360 267 ILESIADGVIAIDRQGKITTMNPAAEVITGLQrheLVGKPYSEL----FPP---NTPFASplldtLEHGTEHVdleisfp 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 91 -----LAISASAT----------GQLILITDLTETRLLQSRISDLQRLSSLGRMVASLAHQVRTPLSSAMLYASNLGAPN 155
Cdd:PRK11360 340 grdrtIELSVSTSllhnthgemiGALVIFSDLTERKRLQRRVARQERLAALGELVAGVAHEIRNPLTAIRGYVQIWRQQT 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 156 LPNATRErFQSKLMDRLHDLEKQVNDMLLFAKGGDNKvIQPFTVTDLVSEFVPMVETALKNSAIDYHQEVEQEGTVVLGN 235
Cdd:PRK11360 420 SDPPSQE-YLSVVLREVDRLNKVIDQLLEFSRPRESQ-WQPVSLNALVEEVLQLFQTAGVQARVDFETELDNELPPIWAD 497
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 236 ANAIASALSNLVMNAIQIAGKASQIDV-FFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQGTGLGLAVVQMVCR 314
Cdd:PRK11360 498 PELLKQVLLNILINAVQAISARGKIRIrTWQYSDGQVAVSIEDNGCGIDPELLKKIFDPFFTTKAKGTGLGLALSQRIIN 577
|
330 340
....*....|....*....|....*.
gi 1447635730 315 AHDGRLELISEEGEGACFTMCIPLER 340
Cdd:PRK11360 578 AHGGDIEVESEPGVGTTFTLYLPINP 603
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
8-341 |
2.14e-44 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 157.02 E-value: 2.14e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 8 INQSHLDSVEDQVERYKQVLDVMPAGVILLDTQGVVREANPEAQRLLQVPLAGEKWYSVIQSAFAPREDDGHEISLRNGR 87
Cdd:COG5002 46 LLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 88 KVRLAISASATGQLILITDLTETRLLQSRISDLQRLSSLGR-MVASLAHQVRTPLSSAMLYASNL-GAPNLPNATRERFQ 165
Cdd:COG5002 126 LLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEQMRReFVANVSHELRTPLTSIRGYLELLlDGAADDPEERREYL 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 166 SKLMDRLHDLEKQVNDMLLFAK--GGDNKV-IQPFTVTDLVSEFVPMVETALKNSAIDYHQEVEQEGTVVLGNANAIASA 242
Cdd:COG5002 206 EIILEEAERLSRLVNDLLDLSRleSGELKLeKEPVDLAELLEEVVEELRPLAEEKGIELELDLPEDPLLVLGDPDRLEQV 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 243 LSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTR------SQGTGLGLAVVQMVCRAH 316
Cdd:COG5002 286 LTNLLDNAIKYTPEGGTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFYRVDksrsreTGGTGLGLAIVKHIVEAH 365
|
330 340
....*....|....*....|....*
gi 1447635730 317 DGRLELISEEGEGACFTMCIPLERH 341
Cdd:COG5002 366 GGRIWVESEPGKGTTFTITLPLARE 390
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
16-345 |
2.13e-41 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 150.90 E-value: 2.13e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 16 VEDQVERYKQVLDVMPAGVILLDTQGVVREANPEAQRLLQVPLA---GEKWYSVIQSAFA---------PREDDGHE--- 80
Cdd:COG5809 136 LRESEEKFRLIFNHSPDGIIVTDLDGRIIYANPAACKLLGISIEeliGKSILELIHSDDQenvaafisqLLKDGGIAqge 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 81 --ISLRNGRKVRLAISASAT-------GQLILITDLTETRLLQSRISDLQRLSSLGRMVASLAHQVRTPLSS-----AML 146
Cdd:COG5809 216 vrFWTKDGRWRLLEASGAPIkkngevdGIVIIFRDITERKKLEELLRKSEKLSVVGELAAGIAHEIRNPLTSlkgfiQLL 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 147 YASNLGapnlpnatRERFQSKLM----DRLHDLekqVNDMLLFAKGGDNKViQPFTVTDLVSEFVPMVETA--LKNsaID 220
Cdd:COG5809 296 KDTIDE--------EQKTYLDIMlselDRIESI---ISEFLVLAKPQAIKY-EPKDLNTLIEEVIPLLQPQalLKN--VQ 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 221 YHQEVEQEGTVVLGNANAIASALSNLVMNAIQIAGKASQIDV-FFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRS 299
Cdd:COG5809 362 IELELEDDIPDILGDENQLKQVFINLLKNAIEAMPEGGNITIeTKAEDDDKVVISVTDEGCGIPEERLKKLGEPFYTTKE 441
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1447635730 300 QGTGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIPLERHAPSS 345
Cdd:COG5809 442 KGTGLGLMVSYKIIEEHGGKITVESEVGKGTTFSITLPIKLSEQVS 487
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
10-338 |
3.19e-40 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 144.93 E-value: 3.19e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 10 QSHLDSVEDQVERYKQVLDVMPAGVILLDTQGVVREANPEAQRLL---QVPLAGE---KWYSVIQSAFAPREDDGHEISL 83
Cdd:COG5807 16 NQEFKLTEDSEFKFKQLFDSILEFVFFIDSKGEILECNDFAEDLYglsQNEYIGKtfvEEKCILKDEQLYNKEAFDRIEI 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 84 RNGRKVRLA---------ISASATGQLILITDLTETRLLQSRISDLQRLSSLGRMVASLAHQVRTPLSSAMLYASNLGAP 154
Cdd:COG5807 96 SYLTKNGEFdeiiypiyyKDGVILGLITVYRDITKRKEAEDKLLRSEKLSVAGELAAGIAHEIRNPLTSIKGFLQLLQES 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 155 NLPNATRERFQsKLMDRLHDLEKQVNDMLLFAKggDNKV-IQPFTVTDLVSEFVPMVET--ALKNSAIDYhqEVEQEGTV 231
Cdd:COG5807 176 REDSEREEYFN-IIISEIDRINTIITELLVLSK--PKKFnFKKLNLNDVLEDVIALLSTeaILKNISIKY--DLADDEPV 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 232 VLGNANAIASALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQGTGLGLAVVQM 311
Cdd:COG5807 251 INGDKNQLKQVFINLIKNAIEAMETGGNITIKTYVEGDFVVISVKDEGIGIPEEVLEKIGEPFFTTKEEGTGLGLSICKK 330
|
330 340
....*....|....*....|....*..
gi 1447635730 312 VCRAHDGRLELISEEGEGACFTMCIPL 338
Cdd:COG5807 331 IIEEHNGTIEVESKPGKGTTFTIYLPL 357
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
16-338 |
8.43e-36 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 135.63 E-value: 8.43e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 16 VEDQVERYKQVLDVMPAGVILLDTQGVVREANPEAQRLLQVP---LAGEKWYSVIQSAFAPR--------EDDGHEISL- 83
Cdd:COG5805 152 LQEQEERLQTLIENSPDLICVIDTDGRILFINESIERLFGAPreeLIGKNLLELLHPCDKEEfkeriesiTEVWQEFIIe 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 84 -----RNGRKVRLAIS--------ASATGQLILITDLTETRLLQSRISDLQRLSSLGRMVASLAHQVRTPLSS-----AM 145
Cdd:COG5805 232 reiitKDGRIRYFEAVivplidtdGSVKGILVILRDITEKKEAEELMARSEKLSIAGQLAAGIAHEIRNPLTSikgflQL 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 146 LYASnlgapnlPNATRERFQskLM-DRLHDLEKQVNDMLLFAKGgDNKVIQPFTVTDLVSEFVPMVETALKNSAIDYHQE 224
Cdd:COG5805 312 LQPG-------IEDKEEYFD--IMlSELDRIESIISEFLALAKP-QAVNKEKENINELIQDVVTLLETEAILHNIQIRLE 381
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 225 VEQEGTVVLGNANAIASALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQGTGL 304
Cdd:COG5805 382 LLDEDPFIYCDENQIKQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEERLKKLGEPFFTTKEKGTGL 461
|
330 340 350
....*....|....*....|....*....|....
gi 1447635730 305 GLAVVQMVCRAHDGRLELISEEGEGACFTMCIPL 338
Cdd:COG5805 462 GLMVSYKIIENHNGTIDIDSKVGKGTTFTITLPL 495
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
101-338 |
1.02e-32 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 126.79 E-value: 1.02e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 101 LILITDLTETRLLQSRISD--LQRLSSLGRMVASLAHQVRTPLSS--AMLYASNLGAPNLPNatrERFQSKLMDRLHDLE 176
Cdd:COG5808 214 LLQYNLLKRKTLLERVIQEinTQKLELIGTFAASTAHEIRNPLTSikGFIQLLQEKYPELED---QKYFDIIQEEIQRIN 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 177 KQVNDMLLFAKGGDNKvIQPFTVTDLVSEFVPMVETALKNSAIDYHQEVEQEGTVVLGNANAIASALSNLVMNAIQIAGK 256
Cdd:COG5808 291 QIVSEFLVLGKPTAKK-LELDDLNELIEEILSIIDSEANLKNIRVEKQSLDEPLHIKCDKDRIKQVLLNLIKNAIEAMKE 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 257 ASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQGTGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCI 336
Cdd:COG5808 370 GGKLTISIENDDEKAVIEVIDNGEGIPEDIIDEIFEPFVTTKEGGTGLGLSVCKRIVEMHGGEIDIESEEGKGTTFTIRL 449
|
..
gi 1447635730 337 PL 338
Cdd:COG5808 450 PL 451
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
20-340 |
1.49e-31 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 122.26 E-value: 1.49e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 20 VERYKQVLDVMPAGVILLDTQGVVREANPEAQRLLQVPLAGEKWYSVIQSAFAPREDDghEISLRNGRKV-----RLAIS 94
Cdd:COG3290 83 VEEREAVLESIREGVIAVDRDGRITLINDAARRLLGLDAIGRPIDEVLAEVLETGERD--EEILLNGRVLvvnrvPIRDD 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 95 ASATGQLILITDLTETRLLQSRISDLQRLSSLGRM-----------VASLAHQVRTplSSAMLYASNLgapnlpNATRER 163
Cdd:COG3290 161 GRVVGAVATFRDRTELERLEEELEGVKELAEALRAqrhdfrnhlhtISGLLQLGEY--DEALEYIDEI------SEELQE 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 164 FQSKLMDRLHDLEkqVNDMLL--FAKGGDNKViqPFTVTdlvsefvpmVETALKNSAIDyhqeveqegtvvlgnANAIAS 241
Cdd:COG3290 233 LIDSLLSRIGNPV--LAALLLgkAARARERGI--DLTID---------IDSDLPDLPLS---------------DTDLVT 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 242 ALSNLVMNAI----QIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTT-RSQGTGLGLAVVQMVCRAH 316
Cdd:COG3290 285 ILGNLLDNAIeaveKLPEEERRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERGFSTkLGEGRGLGLALVKQIVEKY 364
|
330 340
....*....|....*....|....
gi 1447635730 317 DGRLELISEEGEGACFTMCIPLER 340
Cdd:COG3290 365 GGTIEVESEEGEGTVFTVRLPKEG 388
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
234-339 |
1.98e-31 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 114.67 E-value: 1.98e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 234 GNANAIASALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTR-----SQGTGLGLAV 308
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDkrsrkIGGTGLGLSI 80
|
90 100 110
....*....|....*....|....*....|.
gi 1447635730 309 VQMVCRAHDGRLELISEEGEGACFTMCIPLE 339
Cdd:smart00387 81 VKKLVELHGGEISVESEPGGGTTFTITLPLE 111
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
239-334 |
2.79e-29 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 108.46 E-value: 2.79e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 239 IASALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTR----SQGTGLGLAVVQMVCR 314
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGTIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDksreGGGTGLGLAIVRRIVE 80
|
90 100
....*....|....*....|
gi 1447635730 315 AHDGRLELISEEGEGACFTM 334
Cdd:cd00075 81 AHGGRITVESEPGGGTTFTV 100
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
91-338 |
1.16e-28 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 115.27 E-value: 1.16e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 91 LAISASATGQLILITDLT---------ETRLLQSRISDLQRLSSLGRMVASLAHQVRTPLSSAMLYASNLGApNLPNATR 161
Cdd:PRK10364 193 TLIILFALATVLLASLLAffwyrrylrSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAE-RAPAGGE 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 162 ERFQSKLM----DRLHdleKQVNDMLLFAKGGDNKvIQPFTVTDLVSEFVPMVETALKNSAIDYHQEVEQEGTVVLGNAN 237
Cdd:PRK10364 272 AHQLAQVMakeaDRLN---RVVSELLELVKPTHLA-LQAVDLNDLINHSLQLVSQDANSREIQLRFTANDTLPEIQADPD 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 238 AIASALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQGTGLGLAVVQMVCRAHD 317
Cdd:PRK10364 348 RLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHG 427
|
250 260
....*....|....*....|.
gi 1447635730 318 GRLELISEEGEGACFTMCIPL 338
Cdd:PRK10364 428 GTIQVASQEGKGATFTLWLPV 448
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
108-346 |
2.78e-28 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 115.93 E-value: 2.78e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 108 TETRLLQSRISDLQRLSSLGRMVASLAHQVRTPLSSAMLYASNLGAPNLPNATRERFQSKLMDRLHDLEKQVNDMLLFAK 187
Cdd:PRK13837 432 TERDALERRLEHARRLEAVGTLASGIAHNFNNILGAILGYAEMALNKLARHSRAARYIDEIISAGARARLIIDQILAFGR 511
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 188 GGDnKVIQPFTVTDLVSEFVPMVETAL-KNSAIDYHQEveQEGTVVLGNANAIASALSNLVMNAIQIAGKASQIDVFFRP 266
Cdd:PRK13837 512 KGE-RNTKPFDLSELVTEIAPLLRVSLpPGVELDFDQD--QEPAVVEGNPAELQQVLMNLCSNAAQAMDGAGRVDISLSR 588
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 267 V---------NGEL------KISVQDSGPGVPAALQSKIMEPFFTTRSQGTGLGLAVVQMVCRAHDGRLELISEEGEGAC 331
Cdd:PRK13837 589 AklrapkvlsHGVLppgryvLLRVSDTGAGIDEAVLPHIFEPFFTTRAGGTGLGLATVHGIVSAHAGYIDVQSTVGRGTR 668
|
250
....*....|....*
gi 1447635730 332 FTMCIPLERHAPSSP 346
Cdd:PRK13837 669 FDVYLPPSSKVPVAP 683
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
234-340 |
9.58e-27 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 102.06 E-value: 9.58e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 234 GNANAIASALSNLVMNAIQIAGKASQIDVFFRPvNGELKISVQDSGPGVPAALQSKIMEPFFT---TRSQGTGLGLAVVQ 310
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTLSE-GGELTLTVEDNGIGIPPEDLPRIFEPFSTadkRGGGGTGLGLSIVR 79
|
90 100 110
....*....|....*....|....*....|
gi 1447635730 311 MVCRAHDGRLELISEEGEGACFTMCIPLER 340
Cdd:pfam02518 80 KLVELLGGTITVESEPGGGTTVTLTLPLAQ 109
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
20-337 |
4.76e-26 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 107.79 E-value: 4.76e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 20 VERYKQVLDVMPAGVILLDTQGVVREANPEAQRLLqvplaGEKWysviqsafaPrEDDGHEIS----------------- 82
Cdd:PRK11006 97 IKRFRSGAESLPDAVVLTTEEGNIFWCNGLAQQLL-----GFRW---------P-EDNGQNILnllrypeftqylktrdf 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 83 -------LRNGRKVRLAISASATGQLILIT-DLTETRLLQSRISDLqrlsslgrmVASLAHQVRTPLSSAMLYASNLGAP 154
Cdd:PRK11006 162 srpltlvLNNGRHLEIRVMPYTEGQLLMVArDVTQMHQLEGARRNF---------FANVSHELRTPLTVLQGYLEMMQDQ 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 155 NLPNATRERFQSKLMDRLHDLEKQVNDMLLFAKggdnkvIQPFTVTDLVSEF-VPMVETALKNSAIDYHQEVEQ------ 227
Cdd:PRK11006 233 PLEGALREKALHTMREQTQRMEGLVKQLLTLSK------IEAAPTIDLNEKVdVPMMLRVLEREAQTLSQGKHTitfevd 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 228 EGTVVLGNANAIASALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFF---TTRSQ---G 301
Cdd:PRK11006 307 NSLKVFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPQGAEFSVEDNGPGIAPEHIPRLTERFYrvdKARSRqtgG 386
|
330 340 350
....*....|....*....|....*....|....*.
gi 1447635730 302 TGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIP 337
Cdd:PRK11006 387 SGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLP 422
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
103-338 |
5.73e-26 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 107.26 E-value: 5.73e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 103 LITDLTETRLLQSRISDLQRLSSLGRMVASLAHQVRTPLSSAMLYASNLGAPNLPNATRERFQSKLMDRLHDLEKQVNDM 182
Cdd:COG5806 178 LIENLIENILLRKELQRAEKLEVVSELAASIAHEVRNPLTVVRGFIQLLQEPELSDEKRKQYIRIALEELDRAEAIITDY 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 183 LLFAKGgDNKVIQPFTVTDLVSEFVPMVET-ALKNSaIDYHQEVEqEGTVVLGNANAIASALSNLVMNAIQIAGKASQID 261
Cdd:COG5806 258 LTFAKP-QPEKLEKIDVSEELEHVIDVLSPyANMNN-VEIQTELE-PGLYIEGDRQKLQQCLINIIKNGIEAMPNGGTLT 334
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1447635730 262 VFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQGTGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIPL 338
Cdd:COG5806 335 IDVSIDKNKVIISIKDTGVGMTKEQLERLGEPYFSTKEKGTGLGTMVSYRIIEAMNGTIRVESEVGKGTTFTITLPL 411
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
13-341 |
1.86e-24 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 104.10 E-value: 1.86e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 13 LDSVEDQVERYKQVLDVMPAGVILLDTQGVVREANPEAQRLLQVPLAGEKWYSVIQSAFAPREDDGHEISLRNGRKVRLA 92
Cdd:COG4251 160 LLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLL 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 93 ISASATGQLILITDLTETRL--------LQSRISDLQRL-SSLGRMVASLAHQVRTPLSSAMLYASNLG---APNLPNAT 160
Cdd:COG4251 240 LLILLLLLLILVLELLELRLeleeleeeLEERTAELERSnEELEQFAYVASHDLREPLRKISGFSQLLEedyGDKLDEEG 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 161 RERFQsKLMDRLHDLEKQVNDMLLFAK-GGDNKVIQPFTVTDLVSEFVPMVETALKNSAIdyhqEVE-QEGTVVLGNANA 238
Cdd:COG4251 320 REYLE-RIRDAAERMQALIDDLLAYSRvGRQELEFEPVDLNELLEEVLEDLEPRIEERGA----EIEvGPLPTVRGDPTL 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 239 IASALSNLVMNAI--QIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQ----GTGLGLAVVQMV 312
Cdd:COG4251 395 LRQVFQNLISNAIkySRPGEPPRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRLHSRdeyeGTGIGLAIVKKI 474
|
330 340
....*....|....*....|....*....
gi 1447635730 313 CRAHDGRLELISEEGEGACFTMCIPLERH 341
Cdd:COG4251 475 VERHGGRIWVESEPGEGATFYFTLPKAPA 503
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
130-338 |
7.88e-24 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 101.84 E-value: 7.88e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 130 VASLAHQVRTPLSsAMLYASNLGAPNLPNATRERF------QSKLMDRLhdlekqVNDMLLFAK---GGDNKVIQPFTVT 200
Cdd:PRK11100 260 VQTLTHELKSPLA-AIRGAAELLQEDPPPEDRARFtgniltQSARLQQL------IDRLLELARleqRQELEVLEPVALA 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 201 DLVSEFVPMVETALKNSAIDYHQEVEqeGTVVLGNANAIASALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGP 280
Cdd:PRK11100 333 ALLEELVEAREAQAAAKGITLRLRPD--DARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVALSVEDQGP 410
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1447635730 281 GVPAALQSKIMEPFFT-----TRSQGTGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIPL 338
Cdd:PRK11100 411 GIPDYALPRIFERFYSlprpaNGRKSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLPR 473
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
121-328 |
5.98e-22 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 96.30 E-value: 5.98e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 121 QRLSSLGrmvASLAHQVRTPLSSAMLYAS-NLGAPNLPNATRERFQSKLmDRLHDLEKQVNDMLLFAKGGDNKVIQPFTV 199
Cdd:TIGR01386 239 QRLSQFS---ADLAHELRTPLTNLLGQTQvALSQPRTGEEYREVLESNL-EELERLSRMVSDMLFLARADNGQLALERVR 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 200 TDLVSEFvpmvetalkNSAIDYHQEVEQEGTVVL---GNANAIAS------ALSNLVMNAIQIAGKASQIDVFFRPVNGE 270
Cdd:TIGR01386 315 LDLAAEL---------AKVAEYFEPLAEERGVRIrveGEGLVRGDpqmfrrAISNLLSNALRHTPDGGTITVRIERRSDE 385
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1447635730 271 LKISVQDSGPGVPAALQSKIMEPFF------TTRSQGTGLGLAVVQMVCRAHDGRLELISEEGE 328
Cdd:TIGR01386 386 VRVSVSNPGPGIPPEHLSRLFDRFYrvdparSNSGEGTGLGLAIVRSIMEAHGGRASAESPDGK 449
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
243-338 |
5.85e-21 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 86.32 E-value: 5.85e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 243 LSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTR--SQGTGLGLAVVQMVCRAHDGRL 320
Cdd:cd16943 8 LLNLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKpvGEGTGLGLSLSYRIIQKHGGTI 87
|
90
....*....|....*...
gi 1447635730 321 ELISEEGEGACFTMCIPL 338
Cdd:cd16943 88 RVASVPGGGTRFTIILPI 105
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
239-334 |
1.10e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 85.59 E-value: 1.10e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 239 IASALSNLVMNAIQIAGKASQ--IDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTR--SQGTGLGLAVVQMVCR 314
Cdd:cd16976 1 IQQVLMNLLQNALDAMGKVENprIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKpvGKGTGLGLSISYGIVE 80
|
90 100
....*....|....*....|
gi 1447635730 315 AHDGRLELISEEGEGACFTM 334
Cdd:cd16976 81 EHGGRLSVANEEGAGARFTF 100
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
87-338 |
1.14e-19 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 89.61 E-value: 1.14e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 87 RKVRLAISASATGQLILITDLtET---RLLQSRISDLQRLSSLGRMV-------ASLAHQVRTPLSSAMLyASNLgapnl 156
Cdd:PRK09470 195 RKLKNAADEVAQGNLRQHPEL-ETgpqEFRQAGASFNQMVTALERMMtsqqrllSDISHELRTPLTRLQL-ATAL----- 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 157 pnATRERFQSKLMDRL----HDLEKQVNDMLLFAKGGDNKVIQ--PFTVTDLVSEFVPMVETALKNSAIDYHQEVEQEGT 230
Cdd:PRK09470 268 --LRRRQGESKELERIeteaQRLDSMINDLLVLSRNQQKNHLEreTFKANSLWSEVLEDAKFEAEQMGKSLTVSAPPGPW 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 231 VVLGNANAIASALSNLVMNAIQIAgkASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFF---TTR---SQGTGL 304
Cdd:PRK09470 346 PINGNPNALASALENIVRNALRYS--HTKIEVAFSVDKDGLTITVDDDGPGVPEEEREQIFRPFYrvdEARdreSGGTGL 423
|
250 260 270
....*....|....*....|....*....|....
gi 1447635730 305 GLAVVQMVCRAHDGRLELISEEGEGACFTMCIPL 338
Cdd:PRK09470 424 GLAIVENAIQQHRGWVKAEDSPLGGLRLTIWLPL 457
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
243-338 |
1.25e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 82.93 E-value: 1.25e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 243 LSNLVMNAIQ--IAGKAS-QIDVFFRPVNGE-LKISVQDSGPGVPAALQSKIMEPF------FTTRSQGTGLGLAVVQMV 312
Cdd:cd16922 5 LLNLLGNAIKftEEGEVTlRVSLEEEEEDGVqLRFSVEDTGIGIPEEQQARLFEPFsqadssTTRKYGGTGLGLAISKKL 84
|
90 100
....*....|....*....|....*.
gi 1447635730 313 CRAHDGRLELISEEGEGACFTMCIPL 338
Cdd:cd16922 85 VELMGGDISVESEPGQGSTFTFTLPL 110
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
240-337 |
4.86e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 81.18 E-value: 4.86e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 240 ASALSNLVMNAIQIAGKA----SQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQGT-GLGLAVVQMVCR 314
Cdd:cd16915 2 ITIVGNLIDNALDALAATgapnKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGVSTKGQGErGIGLALVRQSVE 81
|
90 100
....*....|....*....|...
gi 1447635730 315 AHDGRLELISEEGEGACFTMCIP 337
Cdd:cd16915 82 RLGGSITVESEPGGGTTFSIRIP 104
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
239-337 |
1.96e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 79.36 E-value: 1.96e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 239 IASALSNLVMNAI----QIAGKASQIDVFFRPVN-GELKISVQDSGPGVPAALQSKIMEPFFTTRSQGTGLGLAVVQMVC 313
Cdd:cd16920 1 IQQVLINLVRNGIeamsEGGCERRELTIRTSPADdRAVTISVKDTGPGIAEEVAGQLFDPFYTTKSEGLGMGLSICRSII 80
|
90 100
....*....|....*....|....
gi 1447635730 314 RAHDGRLELISEEGEGACFTMCIP 337
Cdd:cd16920 81 EAHGGRLSVESPAGGGATFQFTLP 104
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
79-340 |
5.47e-18 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 84.23 E-value: 5.47e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 79 HEISLRNGRKVRLAISA----SATGQLILITDltET-RLLQSRISDLQRLSSLGRMVASLAHQVRTPLSSAML------Y 147
Cdd:PRK09303 101 QEGATYSGLGENLQPSEidsgRYSQELLQLSD--ELfVLRQENETLLEQLKFKDRVLAMLAHDLRTPLTAASLaletleL 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 148 ASNLGAPNLPNATRERFQSKLMDRLHDLEKQVNDMLLFAKGGDNKVI---QPFTVTDLVSEFVPMVETALKNSAIDYHQE 224
Cdd:PRK09303 179 GQIDEDTELKPALIEQLQDQARRQLEEIERLITDLLEVGRTRWEALRfnpQKLDLGSLCQEVILELEKRWLAKSLEIQTD 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 225 VEQEGTVVLGNANAIASALSNLVMNAIQI--AGKASQIDVFFRpVNGELKISVQDSGPGVPAALQSKIMEPFFT-TRSQG 301
Cdd:PRK09303 259 IPSDLPSVYADQERIRQVLLNLLDNAIKYtpEGGTITLSMLHR-TTQKVQVSICDTGPGIPEEEQERIFEDRVRlPRDEG 337
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1447635730 302 T---GLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIPLER 340
Cdd:PRK09303 338 TegyGIGLSVCRRIVRVHYGQIWVDSEPGQGSCFHFTLPVYR 379
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
102-339 |
8.39e-18 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 84.70 E-value: 8.39e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 102 ILITDLTEtRLLQSRISDLQRLSS-----LGRMVASLAHQVRTPLSSA-------MLYASNLGAPNLPNATRERFQSKLM 169
Cdd:PRK10490 636 LLIANALE-RLTLTASEEQARLASereqlRNALLAALSHDLRTPLTVLfgqaeilTLDLASEGSPHARQASEIRQQVLNT 714
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 170 DRLhdlekqVNDMLLFAK---GGDNKVIQPFTVTDLVSEFVPMVETALKNSAIdyHQEVEQEGTVVLGNANAIASALSNL 246
Cdd:PRK10490 715 TRL------VNNLLDMARiqsGGFNLRKEWLTLEEVVGSALQMLEPGLSGHPI--NLSLPEPLTLIHVDGPLFERVLINL 786
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 247 VMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFftTRSQ------GTGLGLAVVQMVCRAHDGRL 320
Cdd:PRK10490 787 LENAVKYAGAQAEIGIDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKF--ARGNkesaipGVGLGLAICRAIVEVHGGTI 864
|
250
....*....|....*....
gi 1447635730 321 ELISEEGEGACFTMCIPLE 339
Cdd:PRK10490 865 WAENRPEGGACFRVTLPLE 883
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
130-346 |
2.23e-17 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 83.42 E-value: 2.23e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 130 VASLAHQVRTPLSSAMLYASNLGAPNLPNATRERFQSkLMDRLHDLEKQVNDMLLFAK---GGDNKVI--QPFTVTDLVS 204
Cdd:PRK11466 448 LAAMSHEIRTPLYGILGTAQLLADNPALNAQRDDLRA-ITDSGESLLTILNDILDYSAieaGGKNVSVsdEPFEPRPLLE 526
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 205 EFVPMVETALKNSAIDY-HQEVEQEGTVVLGNANAIASALSNLVMNAIQIAGKASqIDVFFRPVNGELKISVQDSGPGVP 283
Cdd:PRK11466 527 STLQLMSGRVKGRPIRLaTDIADDLPTALMGDPRRIRQVITNLLSNALRFTDEGS-IVLRSRTDGEQWLVEVEDSGCGID 605
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1447635730 284 AALQSKIMEPF--FTTRSQGTGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIPLERHAPSSP 346
Cdd:PRK11466 606 PAKLAEIFQPFvqVSGKRGGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPLRVATAPVP 670
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
239-338 |
1.26e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 74.39 E-value: 1.26e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 239 IASALSNLVMNAIQIAgkASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFF------TTRSQGTGLGLAVVQMV 312
Cdd:cd16939 1 MARALDNLLRNALRYA--HRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVrldpsrDRATGGFGLGLAIVHRV 78
|
90 100
....*....|....*....|....*.
gi 1447635730 313 CRAHDGRLELISEEGEGACFTMCIPL 338
Cdd:cd16939 79 ALWHGGHVECDDSELGGACFRLTWPR 104
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
242-337 |
1.68e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 74.29 E-value: 1.68e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 242 ALSNLVMNAIQIAGK--ASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQ----GTGLGLAVVQMVCRA 315
Cdd:cd16921 4 VLTNLLGNAIKFRRPrrPPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFQRLHSReeyeGTGVGLAIVRKIIER 83
|
90 100
....*....|....*....|..
gi 1447635730 316 HDGRLELISEEGEGACFTMCIP 337
Cdd:cd16921 84 HGGRIWLESEPGEGTTFYFTLP 105
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
271-337 |
3.59e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 73.59 E-value: 3.59e-16
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1447635730 271 LKISVQDSGPGVPAALQSKIMEPFFTTRSQGTGLGLAVVQMVCRAHDGRLELISEEGEgACFTMCIP 337
Cdd:cd16918 44 LRVSVIDNGPGIPPDLQDTIFYPMVSGRENGTGLGLAIAQNIVSQHGGVIECDSQPGH-TVFSVSLP 109
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
16-329 |
6.21e-16 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 78.79 E-value: 6.21e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 16 VEDQVERYKQVLDVMPAGVILLDTQGVVREANPEAQRL---------------LQVPLAGEKWYSVI--QSAFAPRE--- 75
Cdd:TIGR02938 125 VANQKLLIESVVDAAPVAFVLLDPTGRVILDNQEYKKLatdlrvkepahtvldLLREAWREALAENWpqQLAFSNREarf 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 76 DDGHEISLR----NGRKVRLA-------ISASATGQLIL-ITDLTETRLLQ--SRISDLQ-------RLSSLGRMVASLA 134
Cdd:TIGR02938 205 DRGGGRPARwlscTGSVIGMEsdcadsfFCAAEQPYLLLtIADISNLREEQerARLSALQalmaeeeRLEAIRETLSAAI 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 135 HQVRTPL---SSAMLYASNLGAPNLPNATRERFQSKL---MDRLHDLEKQVndmllfaKGGDNKVIQPFTVTDLVSEFVP 208
Cdd:TIGR02938 285 HRLQGPMnliSAAISVLQRRGDDAGNPASAAMLQQALsagREHMEALRQVI-------PQSPQEIVVPVNLNQILRDVIT 357
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 209 MVETALKNSAIDYHQEVEQEGTVVLGNANAIASALSNLVMNAI----QIAGKASQIDVFFRPVNGELKISVQDSGPGVPA 284
Cdd:TIGR02938 358 LSTPRLLAAGIVVDWQPAATLPAILGRELQLRSLFKALVDNAIeamnIKGWKRRELSITTALNGDLIVVSILDSGPGIPQ 437
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1447635730 285 ALQSKIMEPFFTTRS---QGTGLGLAVVQMVCRAHDGRLELISEEGEG 329
Cdd:TIGR02938 438 DLRYKVFEPFFTTKGgsrKHIGMGLSVAQEIVADHGGIIDLDDDYSEG 485
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
241-337 |
6.38e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 72.62 E-value: 6.38e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 241 SALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQ------GTGLGLAVVQMVCR 314
Cdd:cd16952 3 SAFSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIErcrntgGTGLGLAIVKHVMS 82
|
90 100
....*....|....*....|...
gi 1447635730 315 AHDGRLELISEEGEGACFTMCIP 337
Cdd:cd16952 83 RHDARLLIASELGKGSRFTCLFP 105
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
235-337 |
2.09e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 71.41 E-value: 2.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 235 NANAIASALSNLVMNAIQ-IAGKAS-QIDVFFR---PVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQGTGLGLAVV 309
Cdd:cd16944 1 DTTQISQVLTNILKNAAEaIEGRPSdVGEVRIRveaDQDGRIVLIVCDNGKGFPREMRHRATEPYVTTRPKGTGLGLAIV 80
|
90 100
....*....|....*....|....*...
gi 1447635730 310 QMVCRAHDGRLELISEEGEGACFTMCIP 337
Cdd:cd16944 81 KKIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
243-346 |
2.62e-15 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 77.37 E-value: 2.62e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 243 LSNLVMNAIQIAgKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTT--RSQGTGLGLAVVQMVCRAHDGRL 320
Cdd:PRK15347 518 LVNLLGNAVKFT-ETGGIRLRVKRHEQQLCFTVEDTGCGIDIQQQQQIFTPFYQAdtHSQGTGLGLTIASSLAKMMGGEL 596
|
90 100
....*....|....*....|....*.
gi 1447635730 321 ELISEEGEGACFTMCIPLERHAPSSP 346
Cdd:PRK15347 597 TLFSTPGVGSCFSLVLPLNEYAPPEP 622
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
129-340 |
1.15e-14 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 74.56 E-value: 1.15e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 129 MVASLAHQVRTPLssamlyasnlgapnlpnaTRERFQSKLM----DRLHD-LEKQVNDM-------LLFAKGGDNKVIQP 196
Cdd:PRK09467 232 LMAGVSHDLRTPL------------------TRIRLATEMMseedGYLAEsINKDIEECnaiieqfIDYLRTGQEMPMEM 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 197 FTVTDLVSEfVPMVETalknsaiDYHQEVEQEGT----VVLGNANAIASALSNLVMNAiqiagkasqidvfFRPVNGELK 272
Cdd:PRK09467 294 ADLNALLGE-VIAAES-------GYEREIETALQpgpiEVPMNPIAIKRALANLVVNA-------------ARYGNGWIK 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 273 IS-----------VQDSGPGVPAALQSKIMEPFftTR------SQGTGLGLAVVQMVCRAHDGRLELI-SEEGeGACFTM 334
Cdd:PRK09467 353 VSsgtegkrawfqVEDDGPGIPPEQLKHLFQPF--TRgdsargSSGTGLGLAIVKRIVDQHNGKVELGnSEEG-GLSARA 429
|
....*.
gi 1447635730 335 CIPLER 340
Cdd:PRK09467 430 WLPLTT 435
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
123-346 |
1.84e-14 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 73.87 E-value: 1.84e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 123 LSSLGRMVASLAHQVRTPLSS-----AMLyaSNLGAPNLPNATRERFQsklmdrlhdLEKQVNDMLLFAKGGDNKV---I 194
Cdd:PRK10604 209 IASKKQLIDGIAHELRTPLVRlryrlEMS--DNLSAAESQALNRDIGQ---------LEALIEELLTYARLDRPQNelhL 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 195 QPFTVTDLVSEFVPMVETAlkNSAIDYHQEVEQEGTVVLGNANAIASALSNLVMNAIQIAGKASQIDVFFRPVNGELkiS 274
Cdd:PRK10604 278 SEPDLPAWLSTHLADIQAV--TPEKTVRLDTPHQGDYGALDMRLMERVLDNLLNNALRYAHSRVRVSLLLDGNQACL--I 353
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1447635730 275 VQDSGPGVPAALQSKIMEPFF------TTRSQGTGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIPLERHAPSSP 346
Cdd:PRK10604 354 VEDDGPGIPPEERERVFEPFVrldpsrDRATGGCGLGLAIVHSIALAMGGSVNCDESELGGARFSFSWPVWHNLPQFT 431
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
25-338 |
2.20e-14 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 73.19 E-value: 2.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 25 QVLDVMPAGVILLDTQGVVREANPEAQ--------RLLQVPLAGEKWYSVIQSAFApRE--DDGH-----EISLR-NGRK 88
Cdd:PRK11073 11 QILNSLINSILLLDDDLAIHYANPAAQqllaqssrKLFGTPLPELLSYFSLNIELM-REslQAGQgftdnEVTLViDGRS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 89 VRLAISASATGQLILITDL----TETRLLQSRISDLQRLSSlGRMVASLAHQVRTPLS----SAMLYASNLGAPNLPNAT 160
Cdd:PRK11073 90 HILSLTAQRLPEGMILLEMapmdNQRRLSQEQLQHAQQVAA-RDLVRGLAHEIKNPLGglrgAAQLLSKALPDPALTEYT 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 161 R------ERFQSkLMDRL----HDLEKQVNDMLLFAKggdnKVIQ------PFTVTdLVSEFVPmvetALKNSAIDYHQe 224
Cdd:PRK11073 169 KviieqaDRLRN-LVDRLlgpqRPGTHVTESIHKVAE----RVVQlvslelPDNVR-LIRDYDP----SLPELAHDPDQ- 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 225 VEQegtvvlgnanaiasALSNLVMNAIQIAGK-----------ASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEP 293
Cdd:PRK11073 238 IEQ--------------VLLNIVRNALQALGPeggtitlrtrtAFQLTLHGERYRLAARIDIEDNGPGIPPHLQDTLFYP 303
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1447635730 294 FFTTRSQGTGLGLAVVQMVCRAHDGRLELISEEGEGAcFTMCIPL 338
Cdd:PRK11073 304 MVSGREGGTGLGLSIARNLIDQHSGKIEFTSWPGHTE-FSVYLPI 347
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
114-337 |
4.58e-14 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 73.18 E-value: 4.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 114 QSRISDLQRLSSLGRMVASLAHQVRTPLS--SAMLYASNLGAPNLPNATRERFQSKLMDRLHDLEKQVNDMLLFAKGGDN 191
Cdd:COG4192 421 QDELIQAAKMAVVGQTMTSLAHELNQPLNamSMYLFSAKKALEQENYAQLPTSLDKIEGLIERMDKIIKSLRQFSRKSDT 500
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 192 KvIQPFTVTDLVSEFVPMVETALKNSAIDYHQEVEqegTVVLGNANAIASALSNLVMNAIQIAGKASQIDVFFRPVNGEL 271
Cdd:COG4192 501 P-LQPVDLRQVIEQAWELVESRAKPQQITLHIPDD---LMVQGDQVLLEQVLVNLLVNALDAVATQPQISVDLLSNAENL 576
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1447635730 272 KISVQDSGPGVPAAlqSKIMEPFFTTRSQGTGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIP 337
Cdd:COG4192 577 RVAISDNGNGWPLV--DKLFTPFTTTKEVGLGLGLSICRSIMQQFGGDLYLASTLERGAMVILEFN 640
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
239-337 |
4.67e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 67.47 E-value: 4.67e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 239 IASALSNLVMNAIQIAGKASQIDVFFRPvnGELKISVQDSGPGVPAALQSKIMEPFF---TTR-SQGTGLGLAVVQMVCR 314
Cdd:cd16950 1 LKRVLSNLVDNALRYGGGWVEVSSDGEG--NRTRIQVLDNGPGIAPEEVDELFQPFYrgdNARgTSGTGLGLAIVQRISD 78
|
90 100
....*....|....*....|...
gi 1447635730 315 AHDGRLELISEEGEGACFTMCIP 337
Cdd:cd16950 79 AHGGSLTLANRAGGGLCARIELP 101
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
239-338 |
9.58e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 66.58 E-value: 9.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 239 IASALSNLVMNAIQIAgkASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFF------TTRSQGTGLGLAVVQMV 312
Cdd:cd16949 1 LARALENVLRNALRYS--PSKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYrvdsarDRESGGTGLGLAIAERA 78
|
90 100
....*....|....*....|....*.
gi 1447635730 313 CRAHDGRLELISEEGEGACFTMCIPL 338
Cdd:cd16949 79 IEQHGGKIKASNRKPGGLRVRIWLPA 104
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
106-337 |
3.00e-13 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 70.47 E-value: 3.00e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 106 DLTETRLLQSRISDLQRLSSLGRMVASLAHQVRTPLSSAMLYASNLGAPN-LPNATRERFQSKL------MDRLHDLEKQ 178
Cdd:PRK13557 143 DVSRRRDAEDALRQAQKMEALGQLTGGIAHDFNNLLQVMSGYLDVIQAALsHPDADRGRMARSVeniraaAERAATLTQQ 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 179 vndMLLFAKGG--DNKVIqpfTVTDLVSEFVPMVE--------------TALKNSAIDYHQ-EVeqegtvvlgnanaias 241
Cdd:PRK13557 223 ---LLAFARKQrlEGRVL---NLNGLVSGMGELAErtlgdavtietdlaPDLWNCRIDPTQaEV---------------- 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 242 ALSNLVMNA---------IQIAGKASQIDVFFRPVNGELK------ISVQDSGPGVPAALQSKIMEPFFTTRS--QGTGL 304
Cdd:PRK13557 281 ALLNVLINArdampeggrVTIRTRNVEIEDEDLAMYHGLPpgryvsIAVTDTGSGMPPEILARVMDPFFTTKEegKGTGL 360
|
250 260 270
....*....|....*....|....*....|...
gi 1447635730 305 GLAVVQMVCRAHDGRLELISEEGEGACFTMCIP 337
Cdd:PRK13557 361 GLSMVYGFAKQSGGAVRIYSEVGEGTTVRLYFP 393
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
273-337 |
3.49e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 65.48 E-value: 3.49e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1447635730 273 ISVQDSGPGVPAALQSKIMEPFFTTR--SQGTGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIP 337
Cdd:cd16919 50 LEVSDTGSGMPAEVLRRAFEPFFTTKevGKGTGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
120-322 |
7.31e-13 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 68.84 E-value: 7.31e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 120 LQRLS-SLGR---MVASLAHQVRTPLSSAMLYASNLGAPNLPNAtrerfqSKLMDRLHDLEKQVNDMLLFAKGGDNKVIQ 195
Cdd:PRK10755 127 VSRLTsTLDQerlFTADVAHELRTPLAGIRLHLELLEKQHHIDV------APLIARLDQMMHTVEQLLQLARAGQSFSSG 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 196 PFTVTDLVSEFVPMVETALKNSAIDYHQ-----EVEQEGTVVlGNANAIASALSNLVMNAIQIAGKASQIDVFFRPVNGE 270
Cdd:PRK10755 201 HYQTVKLLEDVILPSQDELSEMLEQRQQtlllpESAADITVQ-GDATLLRLLLRNLVENAHRYSPEGSTITIKLSQEDGG 279
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1447635730 271 LKISVQDSGPGVPAALQSKIMEPF--FTTRSQGTGLGLAVVQMVCRAHDGRLEL 322
Cdd:PRK10755 280 AVLAVEDEGPGIDESKCGELSKAFvrMDSRYGGIGLGLSIVSRITQLHHGQFFL 333
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
243-340 |
2.32e-12 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 67.63 E-value: 2.32e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 243 LSNLVMNAIQIAGKAS--QIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQGTGLGLAVVQMVCRAHDGRL 320
Cdd:PRK11086 438 LGNLIENALEAVGGEEggEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFDKGYSTKGSNRGVGLYLVKQSVENLGGSI 517
|
90 100
....*....|....*....|
gi 1447635730 321 ELISEEGEGACFTMCIPLER 340
Cdd:PRK11086 518 AVESEPGVGTQFFVQIPWDG 537
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
243-338 |
1.60e-11 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 65.38 E-value: 1.60e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 243 LSNLVMNAIQIAGKASQI-DVFFRpvNGELKISVQDSGPGVPAALQSKIMEPFF-----TTR-SQGTGLGLAVVQMVCRA 315
Cdd:PRK10841 567 ISNLLSNAIKFTDTGCIVlHVRVD--GDYLSFRVRDTGVGIPAKEVVRLFDPFFqvgtgVQRnFQGTGLGLAICEKLINM 644
|
90 100
....*....|....*....|...
gi 1447635730 316 HDGRLELISEEGEGACFTMCIPL 338
Cdd:PRK10841 645 MDGDISVDSEPGMGSQFTIRIPL 667
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
226-329 |
4.77e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 59.34 E-value: 4.77e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 226 EQEGTVVLGNANAIASALSNLVMNAIQIAGKASQIDVFFRPVNGELkISVQDSGPGVPAALQSKIMEPFF---TTRSQGT 302
Cdd:cd16940 1 SAADIQVQGDALLLFLLLRNLVDNAVRYSPQGSRVEIKLSADDGAV-IRVEDNGPGIDEEELEALFERFYrsdGQNYGGS 79
|
90 100
....*....|....*....|....*..
gi 1447635730 303 GLGLAVVQMVCRAHDGRLELISEEGEG 329
Cdd:cd16940 80 GLGLSIVKRIVELHGGQIFLGNAQGGG 106
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
245-337 |
2.02e-10 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 57.50 E-value: 2.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 245 NLVMNAIQIA---GKASQIDVFFRPvnGELKISVQDSGPGVPAALQSKIMEPF------FTTRSQGTGLGLAVVQMVCRA 315
Cdd:cd16925 11 NLLSNAFKFTpdgGRIRCILEKFRL--NRFLLTVSDSGPGIPPNLREEIFERFrqgdgsSTRAHGGTGLGLSIVKEFVEL 88
|
90 100
....*....|....*....|..
gi 1447635730 316 HDGRLELISEEGEGACFTMCIP 337
Cdd:cd16925 89 HGGTVTVSDAPGGGALFQVELP 110
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
242-322 |
5.69e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 55.93 E-value: 5.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 242 ALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFT-----TRSQGTGLGLAVVQMVCRAH 316
Cdd:cd16945 8 AINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSlprphSGQKSTGLGLAFVQEVAQLH 87
|
....*.
gi 1447635730 317 DGRLEL 322
Cdd:cd16945 88 GGRITL 93
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
35-343 |
1.01e-09 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 59.53 E-value: 1.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 35 ILLDTQGVVREANPEAQRLLQVPLAGEKWYSVIQSAFAPREDDGHEISLRNGRKVRLAISASATGQLILITDLTETRLLQ 114
Cdd:COG3920 209 LLALLLLLLLLLALLLVLLAALLRLRAAVLEELERRRRARGLGRLLLLLLLLLLLLRALLLLAAGIRLVITERKRAEEEL 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 115 SRISDLQRLsslgrMVASLAHQVRTPLS--SAMLyasNLGAPNLPNATRERFQSKLMDRLHDLEkQVNDMLLfakggDNK 192
Cdd:COG3920 289 EASLEEKEL-----LLRELHHRVKNNLQvvSSLL---RLQARRADDPEAREALEESQNRIQALA-LVHELLY-----QSE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 193 VIQPFTVTDLVSEFVPMVETALKNSAIDYHQEVEqEGTVVLGNANAIASALSNLVMNAIQ---IAGKASQIDVFFRPVNG 269
Cdd:COG3920 355 DWEGVDLRDYLRELLEPLRDSYGGRGIRIELDGP-DVELPADAAVPLGLILNELVTNALKhafLSGEGGRIRVSWRREDG 433
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1447635730 270 ELKISVQDSGPGVPAALqskimepfftTRSQGTGLGLAVVQMVCRAHDGRLELisEEGEGACFTMCIPLERHAP 343
Cdd:COG3920 434 RLRLTVSDNGVGLPEDV----------DPPARKGLGLRLIRALVRQLGGTLEL--DRPEGTRVRITFPLAELAA 495
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
243-338 |
1.16e-09 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 59.57 E-value: 1.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 243 LSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFF-------TTRSQGTGLGLAVVQMVCRA 315
Cdd:PRK11091 403 LWNLISNAVKFTQQGGVTVRVRYEEGDMLTFEVEDSGIGIPEDELDKIFAMYYqvkdshgGKPATGTGIGLAVSKRLAQA 482
|
90 100
....*....|....*....|...
gi 1447635730 316 HDGRLELISEEGEGACFTMCIPL 338
Cdd:PRK11091 483 MGGDITVTSEEGKGSCFTLTIHA 505
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
224-334 |
2.73e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 54.44 E-value: 2.73e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 224 EVEQEGTVVLGNAN--AIASALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFT----- 296
Cdd:cd16947 4 EINIPDRPIYANANteALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTledsr 83
|
90 100 110
....*....|....*....|....*....|....*....
gi 1447635730 297 -TRSQGTGLGLAVVQMVCRAHDGRLELISEEGEGACFTM 334
Cdd:cd16947 84 nSAKQGNGLGLTITKRLAESMGGSIYVNSKPYEKTVFTV 122
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
131-337 |
2.82e-09 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 58.24 E-value: 2.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 131 ASLAHQVRTPLSsamlyasNLGAPNLPNATRERFQSKLMDRLH-DLE------KQVNDMLLFAKGGDNKVI---QPFTVT 200
Cdd:PRK09835 267 ADIAHEIRTPIT-------NLITQTEIALSQSRSQKELEDVLYsNLEeltrmaKMVSDMLFLAQADNNQLIpekKMLDLA 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 201 DLVSEFVPMVETALKNSAIDYHqeVEQEGTVVLGNANAIASALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGP 280
Cdd:PRK09835 340 DEVGKVFDFFEAWAEERGVELR--FVGDPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVENPGT 417
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1447635730 281 GVPAALQSKIMEPFFTT------RSQGTGLGLAVVQMVCRAHDGRLElISEEGEGACFTMCIP 337
Cdd:PRK09835 418 PIAPEHLPRLFDRFYRVdpsrqrKGEGSGIGLAIVKSIVVAHKGTVA-VTSDARGTRFVISLP 479
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
243-337 |
3.49e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 53.73 E-value: 3.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 243 LSNLVMNAIQIAGKAS-QIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTR------SQGTGLGLAVVQMVCRA 315
Cdd:cd16953 5 LRNLIGNAISFSPPDTgRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERpaneafGQHSGLGLSISRQIIEA 84
|
90 100
....*....|....*....|....*.
gi 1447635730 316 HDGRL--ELISEEGE--GACFTMCIP 337
Cdd:cd16953 85 HGGISvaENHNQPGQviGARFTVQLP 110
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
228-332 |
4.34e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 54.18 E-value: 4.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 228 EGTVVLGNANAIASALSNLVMNAIQIAgkASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIME--PFFTTRSQGTGLG 305
Cdd:cd16954 27 PELRFPGERNDLMELLGNLLDNACKWC--LEFVEVTARQTDGGLHLIVDDDGPGVPESQRSKIFQrgQRLDEQRPGQGLG 104
|
90 100
....*....|....*....|....*..
gi 1447635730 306 LAVVQMVCRAHDGRLELISEEGEGACF 332
Cdd:cd16954 105 LAIAKEIVEQYGGELSLSDSPLGGARF 131
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
123-187 |
4.56e-09 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 52.21 E-value: 4.56e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1447635730 123 LSSLGRMVASLAHQVRTPLSSAMLYASNLGAPNLPNATRERFQSKLMDRLHDLEKQVNDMLLFAK 187
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
243-320 |
6.60e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 53.24 E-value: 6.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 243 LSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQ------GTGLGLAVVQMVCRAH 316
Cdd:cd16946 9 FVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSrnrasgGSGLGLAICHNIALAH 88
|
....
gi 1447635730 317 DGRL 320
Cdd:cd16946 89 GGTI 92
|
|
| PAS_8 |
pfam13188 |
PAS domain; PAS domains are involved in many signalling proteins where they are used as a ... |
21-81 |
6.97e-09 |
|
PAS domain; PAS domains are involved in many signalling proteins where they are used as a signal sensor domain. PAS domains appear in archaea, bacteria and eukaryotes. Several PAS-domain proteins are known to detect their signal by way of an associated cofactor. Heme, flavin, and a 4-hydroxycinnamyl chromophore are used in different proteins. This domain recognizes oxygen and CO (Matilla et al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 463802 [Multi-domain] Cd Length: 65 Bit Score: 51.78 E-value: 6.97e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1447635730 21 ERYKQVLDVMPAGVILLDTQGVVREANPEAQRLLQVPLAGEKWYSVIQSAFAPREDDGHEI 81
Cdd:pfam13188 1 ERLRALFESSPDGILVLDEGGRIIYVNPAALELLGYELLGELLGELLDLLDPLLEDALELL 61
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
125-187 |
7.20e-09 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 51.44 E-value: 7.20e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1447635730 125 SLGRMVASLAHQVRTPLSSAMLYASNLGAPNLPNATRERFQsKLMDRLHDLEKQVNDMLLFAK 187
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLRDEKLDEEQREYLE-TILRSAERLLRLINDLLDLSR 62
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
125-187 |
1.14e-08 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 51.03 E-value: 1.14e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1447635730 125 SLGRMVASLAHQVRTPLSSAMLYASNLGAPNLPNATRErFQSKLMDRLHDLEKQVNDMLLFAK 187
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLDTELSEEQRE-YLETILREAERLLRLINDLLDLSR 62
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
246-341 |
1.91e-08 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 55.41 E-value: 1.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 246 LVMNAIQ--IAGKASQ--IDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPfFTTRSQGTGLGLAVVQMVCRAHDG--- 318
Cdd:COG2972 344 LVENAIEhgIEPKEGGgtIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEE-LSSKGEGRGIGLRNVRERLKLYYGeey 422
|
90 100
....*....|....*....|...
gi 1447635730 319 RLELISEEGEGACFTMCIPLERH 341
Cdd:COG2972 423 GLEIESEPGEGTTVTIRIPLEEE 445
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
106-339 |
3.47e-08 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 55.13 E-value: 3.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 106 DLTETR-----LLQSRISDLQRLSSLGRMVASLAHQVRTPLSSAMLYASNLGAPNLPNATRERFQSKLMDRLHDLEKQVN 180
Cdd:PRK09959 687 DITETRdlihaLEVERNKAINATVAKSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIG 766
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 181 DMLLFAK-GGDNKVIQP------FTVTDLVSEFVPMveTALKNSAIDYHQEVEQEGTVVLgNANAIASALSNLVMNAIQI 253
Cdd:PRK09959 767 EILDVDKiESGNYQLQPqwvdipTLVQNTCHSFGAI--AASKSIALSCSSTFPDHYLVKI-DPQAFKQVLSNLLSNALKF 843
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 254 ----AGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTT---RSQ-GTGLGLAVVQMVCRAHDGRLELISE 325
Cdd:PRK09959 844 ttegAVKITTSLGHIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTsagRQQtGSGLGLMICKELIKNMQGDLSLESH 923
|
250
....*....|....
gi 1447635730 326 EGEGACFTMCIPLE 339
Cdd:PRK09959 924 PGIGTTFTITIPVE 937
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
242-333 |
1.13e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 49.59 E-value: 1.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 242 ALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFT-----TRSQGTGLGLAVVQMVCRAH 316
Cdd:cd16948 9 IIGQIVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTgengrNFQESTGMGLYLVKKLCDKL 88
|
90
....*....|....*..
gi 1447635730 317 DGRLELISEEGEGACFT 333
Cdd:cd16948 89 GHKIDVESEVGEGTTFT 105
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
131-349 |
2.03e-07 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 52.93 E-value: 2.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 131 ASLAHQVRTPLssamlyasnlgapnlpNA----TRERFQSKL----MDRLHDLEKQ-------VNDMLLFAKGGDNKVIQ 195
Cdd:PRK11107 298 ANMSHELRTPL----------------NGvigfTRQTLKTPLtptqRDYLQTIERSannllaiINDILDFSKLEAGKLVL 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 196 ---PFTVTDLVSEFVpmveTALKNSA--------IDYHQEVEQEgtvVLGNANAIASALSNLVMNAIQIAGKAS-QIDVF 263
Cdd:PRK11107 362 eniPFSLRETLDEVV----TLLAHSAhekgleltLNIDPDVPDN---VIGDPLRLQQIITNLVGNAIKFTESGNiDILVE 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 264 FRPVNGE---LKISVQDSGPGVPAALQSKIMEPF------FTTRSQGTGLGLAVVQMVCRAHDGRLELISEEGEGACFTM 334
Cdd:PRK11107 435 LRALSNTkvqLEVQIRDTGIGISERQQSQLFQAFrqadasISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWF 514
|
250
....*....|....*..
gi 1447635730 335 CIPLE--RHAPSSPTET 349
Cdd:PRK11107 515 HLPLDlnPNPIIDGLPT 531
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
113-335 |
1.03e-06 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 50.03 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 113 LQSRISDLqrLSSLGRMVASLAHQVRTPLSS-------AMLYA----------SNLGApNLPNATRERFQSKLMDRLhDL 175
Cdd:PRK10337 226 LFARTHAM--MVRERRFTSDAAHELRSPLAAlkvqtevAQLSDddpqarkkalLQLHA-GIDRATRLVDQLLTLSRL-DS 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 176 EKQVNDMllfakggdnkviQPFTVTDLVSEFVPMVETALKNSAIDYHQEVEQEGTVVLGNANAIASALSNLVMNAIQIAG 255
Cdd:PRK10337 302 LDNLQDV------------AEIPLEDLLQSAVMDIYHTAQQAGIDVRLTLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSP 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 256 KASQIDVFFRPVNgelkISVQDSGPGV-PAALQsKIMEPFFTTRSQ---GTGLGLAVVQMVCRAHDGRLELISEEGEGAC 331
Cdd:PRK10337 370 QGSVVDVTLNARN----FTVRDNGPGVtPEALA-RIGERFYRPPGQeatGSGLGLSIVRRIAKLHGMNVSFGNAPEGGFE 444
|
....
gi 1447635730 332 FTMC 335
Cdd:PRK10337 445 AKVS 448
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
132-341 |
3.07e-06 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 47.69 E-value: 3.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 132 SLAHQvrtpLSSAMLYASNLG--APNLPNATRERFQsKLMDRLHDLEKQVNDMLlfakggdnKVIQP--FTVTDLVSEFV 207
Cdd:COG4585 64 GVGQS----LSAIKLQLEAARrlLDADPEAAREELE-EIRELAREALAELRRLV--------RGLRPpaLDDLGLAAALE 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 208 PMVETALKNSAIDYHQEVEQEGTVVLGN-ANAIASALSNLVMNAIQIAGkASQIDVFFRPVNGELKISVQDSGPGVPAAl 286
Cdd:COG4585 131 ELAERLLRAAGIRVELDVDGDPDRLPPEvELALYRIVQEALTNALKHAG-ATRVTVTLEVDDGELTLTVRDDGVGFDPE- 208
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1447635730 287 qskimepffttRSQGTGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIPLERH 341
Cdd:COG4585 209 -----------AAPGGGLGLRGMRERAEALGGTLTIGSAPGGGTRVRATLPLAAA 252
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
235-336 |
3.09e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 45.53 E-value: 3.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 235 NANAIASALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFT----TRSQG-TGLGLAVV 309
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRddtsRRSGGhYGMGLYIA 80
|
90 100
....*....|....*....|....*..
gi 1447635730 310 QMVCRAHDGRLELISEEGEGACFTMCI 336
Cdd:cd16975 81 KNLVEKHGGSLIIENSQKGGAEVTVKI 107
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
131-343 |
1.22e-05 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 46.94 E-value: 1.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 131 ASLAHQVRTPLS--SAMLYASNLGAPNLPNATRERFQS------KLMDRLHDLEKQVNDMLLFAKggdnkviqpfTVTDL 202
Cdd:PRK10549 245 ADISHELRTPLAvlRGELEAIQDGVRKFTPESVASLQAevgtltKLVDDLHQLSLSDEGALAYRK----------TPVDL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 203 VsefvPMVETAL---------KNSAIDYHQEveqEGTVVLGNANAIASALSNLVMNAIQIAGKASQIDVFFRPVNGELKI 273
Cdd:PRK10549 315 V----PLLEVAGgafrerfasRGLTLQLSLP---DSATVFGDPDRLMQLFNNLLENSLRYTDSGGSLHISAEQRDKTLRL 387
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1447635730 274 SVQDSGPGVPAALQSKIMEPFFTTR------SQGTGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIPLERHAP 343
Cdd:PRK10549 388 TFADSAPGVSDEQLQKLFERFYRTEgsrnraSGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQ 463
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
236-338 |
2.38e-05 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 43.36 E-value: 2.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 236 ANAIASALSNLVMNAIQIAGKAS---QIDVFFRPVNGELKISVQDSGPGVPAAlqsKIMEPFFTTRsqGTGLGLAVVQMV 312
Cdd:COG2172 32 ADDLVLAVSEAVTNAVRHAYGGDpdgPVEVELELDPDGLEIEVRDEGPGFDPE---DLPDPYSTLA--EGGRGLFLIRRL 106
|
90 100
....*....|....*....|....*.
gi 1447635730 313 CRahdgRLELISEEGeGACFTMCIPL 338
Cdd:COG2172 107 MD----EVEYESDPG-GTTVRLVKRL 127
|
|
| RocR |
COG3829 |
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis ... |
15-127 |
2.67e-05 |
|
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis domains [Transcription, Signal transduction mechanisms];
Pssm-ID: 443041 [Multi-domain] Cd Length: 448 Bit Score: 45.92 E-value: 2.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 15 SVEDQVERYKQVLDVMPAGVILLDTQGVVREANPEAQRLLQVP---LAGEKWYSVIQS-----AFAPREDDGHEISLRNG 86
Cdd:COG3829 5 ELKELEEELEAILDSLDDGIIVVDADGRITYVNRAAERILGLPreeVIGKNVTELIPNsplleVLKTGKPVTGVIQKTGG 84
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1447635730 87 RKVRLAISAS-------ATGQLILITDLTETRLLQSRISDLQRLSSLG 127
Cdd:COG3829 85 KGKTVIVTAIpifedgeVIGAVETFRDITELKRLERKLREEELERGLS 132
|
|
| PAS_4 |
pfam08448 |
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
27-111 |
1.06e-04 |
|
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. This domain is associated to signalling systems and works as a signal sensor domain. It recognizes differently substituted aromatic hydrocarbons, oxygen, different dodecanoic acids, autoinducers, 3,5-dimethyl-pyrazin-2-ol and N-alanyl-aminoacetone (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 312075 [Multi-domain] Cd Length: 110 Bit Score: 41.25 E-value: 1.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 27 LDVMPAGVILLDTQGVVREANPEAQRLLQVPLA---GEKWYSVIQSAFAPRED-------------DGHEISLRNGRKVR 90
Cdd:pfam08448 1 LDSLPDALAVLDPDGRVRYANAAAAELFGLPPEellGKTLAELLPPEDAARLEralrralegeepiDFLEELLLNGEERH 80
|
90 100
....*....|....*....|....*....
gi 1447635730 91 LAISAS--------ATGQLILITDLTETR 111
Cdd:pfam08448 81 YELRLTplrdpdgeVIGVLVISRDITERR 109
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
242-337 |
1.11e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 40.83 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 242 ALSNLVMNAIQIAGKASQIDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFF---TTR-SQGTGLGLAVVQMVCRAHD 317
Cdd:cd16923 4 VFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYrgdNSRnTEGAGLGLSIAKAIIELHG 83
|
90 100
....*....|....*....|
gi 1447635730 318 GRLElISEEGEGACFTMCIP 337
Cdd:cd16923 84 GSAS-AEYDDNHDLFKVRLP 102
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
290-337 |
1.43e-04 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 42.18 E-value: 1.43e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1447635730 290 IMEPFFTTRSQ-----GTGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIP 337
Cdd:cd16916 126 IFAPGFSTAEQvtdvsGRGVGMDVVKRSIESLGGTIEVESEPGQGTTFTIRLP 178
|
|
| PAS |
smart00091 |
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
21-84 |
1.54e-04 |
|
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels.
Pssm-ID: 214512 Cd Length: 67 Bit Score: 39.30 E-value: 1.54e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1447635730 21 ERYKQVLDVMPAGVILLDTQGVVREANPEAQRLLQVP---LAGEKWYSVIQSAFAPREDDGHEISLR 84
Cdd:smart00091 1 ERLRAILESLPDGIFVLDLDGRILYANPAAEELLGYSpeeLIGKSLLELIHPEDRERVQEALQRLLS 67
|
|
| CheA |
COG0643 |
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms]; |
290-338 |
2.49e-04 |
|
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms];
Pssm-ID: 440408 [Multi-domain] Cd Length: 563 Bit Score: 42.86 E-value: 2.49e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1447635730 290 IMEPFFTTRSQ-----GTGLGLAVVQMVCRAHDGRLELISEEGEGACFTMCIPL 338
Cdd:COG0643 365 IFAPGFSTAEEvtdlsGRGVGMDVVKTNIEALGGTIEIESEPGKGTTFTLRLPL 418
|
|
| PAS |
pfam00989 |
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
21-57 |
2.09e-03 |
|
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. This domain can bind gases (O2, CO and NO), FAD, 4-hydroxycinnamic acid and NAD+ (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 395786 [Multi-domain] Cd Length: 113 Bit Score: 37.40 E-value: 2.09e-03
10 20 30
....*....|....*....|....*....|....*..
gi 1447635730 21 ERYKQVLDVMPAGVILLDTQGVVREANPEAQRLLQVP 57
Cdd:pfam00989 1 EDLRAILESLPDGIFVVDEDGRILYVNAAAEELLGLS 37
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
235-337 |
2.22e-03 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 39.82 E-value: 2.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 235 NANAIASALSNLVMNAIQIAGKASQ----IDVFFRPVNGELKISVQDSGPGVPAALQSKIMEPFFTTRSQGT---GLGLA 307
Cdd:PRK15053 429 DSTEFAAIVGNLLDNAFEASLRSDEgnkiVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEPgehGIGLY 508
|
90 100 110
....*....|....*....|....*....|
gi 1447635730 308 VVQMVCRAHDGRLELISEEGEGACFTMCIP 337
Cdd:PRK15053 509 LIASYVTRCGGVITLEDNDPCGTLFSIFIP 538
|
|
| HATPase_RsbW-like |
cd16936 |
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase ... |
242-315 |
3.22e-03 |
|
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.
Pssm-ID: 340413 [Multi-domain] Cd Length: 91 Bit Score: 36.48 E-value: 3.22e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1447635730 242 ALSNLVMNAIQIAGKASQ---IDVFFRPVNGELKISVQDSGPGVPaalQSKIMEPffTTRSQGTGLGLAVVQMVCRA 315
Cdd:cd16936 4 AVSEAVTNAVRHAYRHDGpgpVRLELDLDPDRLRVEVTDSGPGFD---PLRPADP--DAGLREGGRGLALIRALMDE 75
|
|
| PAS |
COG2202 |
PAS domain [Signal transduction mechanisms]; |
21-117 |
3.23e-03 |
|
PAS domain [Signal transduction mechanisms];
Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 38.85 E-value: 3.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 21 ERYKQVLDVMPAGVILLDTQGVVREANPEAQRLL---------------QVPLAGEKWYSVIQSAFAPREDDGH-EISLR 84
Cdd:COG2202 137 ERLRLLVENAPDGIFVLDLDGRILYVNPAAEELLgyspeellgkslldlLHPEDRERLLELLRRLLEGGRESYElELRLK 216
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1447635730 85 NGRKVRLAISASA---------TGQLILITDLTETRLLQSRI 117
Cdd:COG2202 217 DGDGRWVWVEASAvplrdggevIGVLGIVRDITERKRAEEAL 258
|
|
| PRK13560 |
PRK13560 |
hypothetical protein; Provisional |
103-338 |
5.23e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 106506 [Multi-domain] Cd Length: 807 Bit Score: 38.89 E-value: 5.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 103 LITDLTETRLLQSRISdlQRLSSLGRMVASLAHQVRTPLS--SAMLY--ASNLGAPNLPNATRERfQSKL--MDRLHDLE 176
Cdd:PRK13560 584 IVIDISERKHAEEKIK--AALTEKEVLLKEIHHRVKNNLQiiSSLLDlqAEKLHDEEAKCAFAES-QDRIcaMALAHEKL 660
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 177 KQVNDMllfakggdnkviQPFTVTDLVSEFVPMVET--ALKNSAIDYHQEVeqeGTVVLGNANAIASAL--SNLVMNAIQ 252
Cdd:PRK13560 661 YQSEDL------------ADIDFLDYIESLTAHLKNsfAIDFGRIDCKIDA---DDGCLDIDKAIPCGLiiSELLSNALK 725
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 253 IA---GKASQIDV-FFRPVNGELKISVQDSGPGVPAALQSKIMEPffttrsqgtgLGLAVVQMVCRAHDGRLELISEegE 328
Cdd:PRK13560 726 HAfpdGAAGNIKVeIREQGDGMVNLCVADDGIGLPAGFDFRAAET----------LGLQLVCALVKQLDGEIALDSR--G 793
|
250
....*....|
gi 1447635730 329 GACFTMCIPL 338
Cdd:PRK13560 794 GARFNIRFPM 803
|
|
| PAS |
COG2202 |
PAS domain [Signal transduction mechanisms]; |
17-126 |
6.70e-03 |
|
PAS domain [Signal transduction mechanisms];
Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 37.70 E-value: 6.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447635730 17 EDQVERYKQVLDVMPAGVILLDTQGVVREANPEAQRL---------------LQVPLAGEKWYSVIQSAFAPREDDGHEI 81
Cdd:COG2202 7 EESERRLRALVESSPDAIIITDLDGRILYVNPAFERLtgysaeellgktlrdLLPPEDDDEFLELLRAALAGGGVWRGEL 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1447635730 82 SLR--NGRKVRLAISAS----ATGQLI----LITDLTETRLLQSRISDL-QRLSSL 126
Cdd:COG2202 87 RNRrkDGSLFWVELSISpvrdEDGEITgfvgIARDITERKRAEEALRESeERLRLL 142
|
|
| |
