|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10189 |
PRK10189 |
EmmdR/YeeO family multidrug/toxin efflux MATE transporter; |
1-478 |
0e+00 |
|
EmmdR/YeeO family multidrug/toxin efflux MATE transporter;
Pssm-ID: 182293 [Multi-domain] Cd Length: 478 Bit Score: 827.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 1 MNVSAALRQVASRTPWYAKRKSYKVLFWREITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAF 80
Cdd:PRK10189 1 LNISSALRQVVHGTRWYAKRKSYRVLFWREITPLAVPIFIENLCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 81 FAAIDLGTTVVVAFSLGKRDRRRARAAARQSLVIMTIFATVLAAVIHYFGQQIIDVVAGEATPDVKALALTYLELTVLSY 160
Cdd:PRK10189 81 FAAIDLGTTVVVAFSLGKRDRRRARAAARQSLVIMTLFAVLLAVLIHFFGEQIIDLVAGDATPEVKALALTYLELTVWSY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 161 PAAAIALIGSGALRGAGNTKIPLLINGGMNILNIIISSILIYGIFSWQGLGFVGAGLGLTISRYIGAIAIIWVLMIGFNP 240
Cdd:PRK10189 161 PAAAITLIGSGALRGAGNTKIPLLINGGMNILNIIISSILIYGLFSWQGLGFVGAGLGLTISRYIGAVAIIWVLMIGFNP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 241 ALRIPFKSYFKPLNLAIIWEVMGIGIPASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTI 320
Cdd:PRK10189 241 ALRISLKSYFKPLNFAIIWEVMGIGIPASIESVLFNGGKLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGNALGSASTI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 321 ITGRRLGNGQIAQAEIQLRHVFWLSTIGLTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAG 400
Cdd:PRK10189 321 ITGTRLGKGQIAQAERQLRHVFWLSTLGLTAIAWLSAPFAGLLASFYTQDPDVKHVVKILIWLNALFMPIWAASWVLPAG 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1476636197 401 FKGARDARFAMWVSMLGMWGCRVVAGYTLGIVLGWGVVGVWLGMFFDWAVRAALFYWRMVTGRWLWKYPRPEREKCIK 478
Cdd:PRK10189 401 LKGARDARYAMWVSMLGMWGCRVVAGYILGIMLGFGVVGVWMGMFLDWAVRGVLFYWRMVSGRWLWKYPRPEPQKCEK 478
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
29-465 |
7.45e-100 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 306.36 E-value: 7.45e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 29 REITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAA 108
Cdd:cd13137 1 RRIWSLAWPVILENLLQTLVGLVDVFMVGRLGAEAIAAVGLATQVLWLLLVLNMALGTGTVALVSQSYGAGDYERARRAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 109 RQSLVIMTIFATVLAAVIHYFGQQIIDVVAgeATPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLLINGG 188
Cdd:cd13137 81 GQSLLLALLLSLPLALLGLLFAEPLLRLLG--ADPEVIALALTYLRIVLLGIPFFFLSLVGNAALRGAGDTKTPMYIMII 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 189 MNILNIIISSILIYGIFSWQGLGFVGAGLGLTISRYIGAIAIIWVLMIGFNPalrIPFKSYFKPLNLAIIWEVMGIGIPA 268
Cdd:cd13137 159 VNVLNIVLDYVLIFGLWGFPGLGVAGAALATVISRVVGALLLLFLLLRGRLP---IKISFKGFRLDRKIIKKLLRIGLPA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 269 SIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLSTIG 348
Cdd:cd13137 236 GLEQLLRSLGFLVLLAIVASYGTAALAAYQIGLRIESLAFMPGFGFSMAASTLVGQNLGAGDPDEARRYGKRALRLGVLF 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 349 LTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLGMWGCRVVAGYT 428
Cdd:cd13137 316 MGLLGLLLFIFAPPLASLFTPDPEVIELGVLYLRIVALSQPFLAISFVLSGALRGAGDTRPPLIINLISMWLVRLPLAYL 395
|
410 420 430
....*....|....*....|....*....|....*..
gi 1476636197 429 LGIVLGWGVVGVWLGMFFDWAVRAALFYWRMVTGRWL 465
Cdd:cd13137 396 LGFVLGLGLTGIWLAMFVDTIVRAILLLYRFRKGKWK 432
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
29-465 |
6.79e-74 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 239.71 E-value: 6.79e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 29 REITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAA 108
Cdd:cd13134 3 LSLFALAWPIFIELLLQMLLGTIDTFMLSRYSDNAVAAVGVANQILFLLILIFSFISTGTSILIAQYLGAKDKKKARQIA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 109 RQSLVIMTIFATVLAAVIHYFGQQIIDVvaGEATPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLLINGG 188
Cdd:cd13134 83 GVALLFNLLLGLVFSLLLLFFGAELLRL--MGLPPELLALGSTYLRIVGGSLFLQALSLTLSAILRSHGRTKIPMYVSLI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 189 MNILNIIISSILIYGIFSWQGLGFVGAGLGLTISRYIGAIAIIWVLMIGFNPALRIpfkSYFKPLNLAIIWEVMGIGIPA 268
Cdd:cd13134 161 MNILNIVGNYLLIFGWFGLPKLGVAGVAISTVISRAVGLVLLFILLFRKLKIRFRL---KDLRPFPKKLLKKILKIGLPS 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 269 SIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLSTIG 348
Cdd:cd13134 238 AGEELSYNLSQTVITAFIARLGTAALAARTYASNISMFVFLFSLAIGQATQIIVGHLVGAGDFDEAYKRVLKSLKIGLLV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 349 LTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLGMWGCRVVAGYT 428
Cdd:cd13134 318 SLAVALLLALFREPILGLFTDDPEIIALGKTLLLISILLEPGRAFNIVLIGSLRAAGDARFPVLIGIISMWGISVPLAYL 397
|
410 420 430
....*....|....*....|....*....|....*..
gi 1476636197 429 LGIVLGWGVVGVWLGMFFDWAVRAALFYWRMVTGRWL 465
Cdd:cd13134 398 LGIVLGLGLLGVWIAFAADEWVRGIIMLWRWRSGKWI 434
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
27-458 |
9.85e-73 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 236.19 E-value: 9.85e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 27 FWREITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARA 106
Cdd:COG0534 6 ILKLLLRLALPIILGNLLQSLYGLVDTIFVGRLGTAALAAVGLAFPIFFLLIALGIGLGVGGTALVAQALGAGDREEARR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 107 AARQSLVIMTIFATVLAAVIHYFGQQIIDVVAgeATPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLLIN 186
Cdd:COG0534 86 VLGQALLLALLLGLLLTLLGLLFAPPLLRLLG--ADPEVLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTPMIIM 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 187 GGMNILNIIISSILIYGIfswqGLGFVGAGLGLTISRYIGAIAIIWVLMIGFNPaLRIPFKSYfkPLNLAIIWEVMGIGI 266
Cdd:COG0534 164 LIGNVLNIVLDPLLIFGG----GLGVAGAALATVISQAVSALLLLYYLFRKRSL-LRLRLRDL--RPDRKILKRILRIGL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 267 PASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLST 346
Cdd:COG0534 237 PAGLQQLAESLGFLVLNALVARLGTAAVAAYGIALRIESLAFMPALGLGQAAQPLVGQNLGAGDYDRARRAARLALLLAL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 347 IGLTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLGMWGCRVVAG 426
Cdd:COG0534 317 GIGLLLALLLFLFPEPIIGLFTDDPEVIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFPMIISLLRLWLVRLPLA 396
|
410 420 430
....*....|....*....|....*....|..
gi 1476636197 427 YTLGIvLGWGVVGVWLGMFFDWAVRAALFYWR 458
Cdd:COG0534 397 YLLAF-LGLGLTGVWLALPIGEVLRALLLLLR 427
|
|
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
28-464 |
4.96e-46 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 165.78 E-value: 4.96e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 28 WREITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAA 107
Cdd:cd13133 4 YREILKIALPLVLSMLSQTVMGFTDRAFLGRLSEVALAASGPAGVLYFAILMLFFGLSSGVQVFVAQYNGAGRYSRIGRV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 108 ARQSLVIMTIFATVLAAVIHYFGQQIIDVVAGEatPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLLING 187
Cdd:cd13133 84 LWQGLYFSLLLAPLLALLSALAAPLLFLLLGHS--PEVQALEVEYFRIRILGAPFSLLGAALRAFFSGIGRTRVVMVANL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 188 GMNILNIIISSILIYGIFSWQGLGFVGAGLGLTISRYIGAIAIIWVLMIGFNPAlRIPFKSYFKPlNLAIIWEVMGIGIP 267
Cdd:cd13133 162 VMVVVNIVLDYALIFGKLGFPAMGIAGAAIATVIAEAVSLLFFLLLLFRRKNRR-RFGLRRAWRF-DRELLRRILRLGLP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 268 ASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLSTI 347
Cdd:cd13133 240 SGLQFFLDVGAFTVFFLLIGRLGTTELAATNIVFSINSLAFLPMIGLGIAVSSLVGQALGAGRPDLAMRVTRRGLKLALA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 348 GLTAIAWLTAPFAGVMASFYTHDQDVKEVI---VILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLGMWGCrVV 424
Cdd:cd13133 320 YMLLLGILFLLFPELLLSIFTPGADFALIAelaVPLLRFVAAYILFDALALVFAGALRGAGDTRFVMLAELIVAWLY-LL 398
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 1476636197 425 AGYTLGIVLGWGVVGVWLGMFFDWAVRAALFYWRMVTGRW 464
Cdd:cd13133 399 PPAYLLVVLGAGLAGAWTVETVYVIVLALIFLLRFRSGKW 438
|
|
| MATE_like_12 |
cd13142 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
23-445 |
4.44e-45 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240547 [Multi-domain] Cd Length: 444 Bit Score: 163.52 E-value: 4.44e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 23 YKVLFWreitpLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRR 102
Cdd:cd13142 10 LRTLLK-----LAWPIIVSNLLQVAYNLADTFWLGRLGADAVAAPSISWPLIFLFISLGGGLTVAGTALVAQYTGAGDYD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 103 RARAAARQSLVIMTIFATVLAAVIHYFGQQIIDVVAGeATPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIP 182
Cdd:cd13142 85 KANKVAGQTFSFVIILSLILAVLGYILSRPLLLLLIG-APEEVYPLALAYLRIIFLGLPFMFIFFVFNSLLRGIGDTKTP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 183 LLINGGMNILNIIISSILIYGIFSWQGLGFVGAGLGLTISRYIGAIAIIWVLMIGFnPALRIPFKSyFKPlNLAIIWEVM 262
Cdd:cd13142 164 MKIMFGSVLLNVILDPLLIFGIGPFPGLGVAGAALATVISRGIAAVIGLYLLFKGR-VGLKISLRD-LKP-DWEWLKKIF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 263 GIGIPASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVF 342
Cdd:cd13142 241 RIGLPSSIEQSARALGFTVMTALVAGFGTVVVAAYGIGNRIISLVFLPAFGLARATSTMVGQNLGAGQIDRAEEIVKKAA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 343 WLSTIGLTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLGMWGCR 422
Cdd:cd13142 321 LLIFLILVIGGVLAFLFAEPIVRVFINDPEVIKEGADFLRIVAPSFPFFGLFQVINGAFRGSGHTLTAMIISILRLWVIR 400
|
410 420
....*....|....*....|...
gi 1476636197 423 VVAGYTLGIVLGWGVVGVWLGMF 445
Cdd:cd13142 401 IPLAYLLAYVLGLGVTGIWIAMA 423
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
28-464 |
5.17e-45 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 163.01 E-value: 5.17e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 28 WREITPLAVPIFLENTCVLLMGVLSTFLVS-WLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARA 106
Cdd:cd13138 2 LKTLLLFALPLLLSNLLQQLYNLVDLLIVGqFLGVAALAAVSNGSPIIFLLTAIGMGLSMGGTILISQYIGAKDEEKAKK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 107 AARQSLVIMTIFATVLAAVIHYFGQQIIDVVAgeATPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLLIN 186
Cdd:cd13138 82 AVGTLLVLFLILGIVLTILGLLFAPPILRLMN--TPAEILELAVSYLRICFLGIPFIFGYNAYSAILRGLGDSKTPLYFV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 187 GGMNILNIIISSILIYGIfswqGLGFVGAGLGLTISRYIGAIAIIWVLMIGFNPaLRIPFKSYfkPLNLAIIWEVMGIGI 266
Cdd:cd13138 160 IIACVLNIILDLLFIAVF----HMGVAGAALATVIAQAISVLLALYYLRKKKLP-FKLSLKDF--RFDKEILKEILKIGL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 267 PASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLST 346
Cdd:cd13138 233 PSALQQSLVSISFLIINSIVNSYGVVASAAYGIANKINSFAFLPPSAIGQAVSTFVAQNIGAGKIERAKKGLRTGIIISL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 347 IGLTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLGMWGCRVVAG 426
Cdd:cd13138 313 IIGLIIILLVFFFAPQLLGLFTSDPEVIEIGAEYLRIYSIDYILFGILFVFNGLFRGLGKTKFPMIISILRLWLVRIPLA 392
|
410 420 430
....*....|....*....|....*....|....*...
gi 1476636197 427 YTLGIVLGWGVVGVWLGMFFDWAVRAALFYWRMVTGRW 464
Cdd:cd13138 393 YLLSRLTGLGLFGIWLAMPISNILSAIICIIYYRKGRW 430
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
37-383 |
8.53e-33 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 127.36 E-value: 8.53e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 37 PIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAARQSLVIMT 116
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHLGPVDLAAVSLGSSVFMFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLLLAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 117 IFATVLAAVIHYFGQQIIDvvAGEATPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLLINGGMNILNIII 196
Cdd:TIGR00797 81 LLGLPVLLVGYFFIDPLLS--LMGADGEVAELAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMYITLIGNVINIIL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 197 SSILIYGIFSWqgLGFVGAGLGLTISRYIGAIAIIWVLMIGfnPALRIPFKSYFKPlNLAIIWEVMGIGIPASIESVLFN 276
Cdd:TIGR00797 159 NYILIFGKFGF--LGIVGAALATVISYWLMFLLLLYYIKKA--KKIGLKWEGLLKP-DWEVLKRLLKLGLPIAFRVILES 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 277 GGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLSTIGLTAIAWLT 356
Cdd:TIGR00797 234 LSFALLALLVARLGSIALAAHQIALNVESLLFMPAFGFGIAVSILVGQALGAGDPKRAKEVARVALKLSLLLGLVLAIIL 313
|
330 340
....*....|....*....|....*..
gi 1476636197 357 APFAGVMASFYTHDQDVKEVIVILIWL 383
Cdd:TIGR00797 314 ILFREFIARLFTNDPEVLELAAIYLIF 340
|
|
| MATE_NorM_like |
cd13131 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio ... |
28-460 |
2.90e-32 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate.
Pssm-ID: 240536 [Multi-domain] Cd Length: 435 Bit Score: 128.00 E-value: 2.90e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 28 WREITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAA 107
Cdd:cd13131 2 LRALLRLALPILIAQLAQMAMGFVDTVMAGRLGADDLAAVALGSSLWFPVFTFGMGLLLAVTPLVAQAHGAGDRRRIRRA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 108 ARQSLVIMTIFATVLAAVI-------HYFGQqiidvvageaTPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTK 180
Cdd:cd13131 82 VRQGLWLALLLSLPLMLLLwlappilPLMGQ----------EPEVAAIARGYLLALAWGIPPALLFQVLRSFLDALGRTR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 181 IPLLINGGMNILNIIISSILIYGIFSWQGLGFVGAGLGLTISRYIGAIAIIWVLmigfnpALRIPFKSY-----FKPLNL 255
Cdd:cd13131 152 PAMVITLLALVLNIPLNYVLIFGKFGLPALGGAGAGLATAIVYWLMFLALAFYI------RRHKRFRRYrlfarFWRPDW 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 256 AIIWEVMGIGIPASI----ESVLFNGGKLLtqmfVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQI 331
Cdd:cd13131 226 ARLKELLRLGLPIGLtiffEVSLFAAVALL----MGRLGTTVLAAHQIALNFASLLFMVPLGISMAATVRVGFALGAGDP 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 332 AQAEIQLRHVFWLSTIGLTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAM 411
Cdd:cd13131 302 ADARRAGLVGLGLGVGFAALTALLLLLFPEQIAGLYTNDPAVIALAASLLVFAALFQLFDGIQVVAAGALRGYKDTRVPF 381
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 1476636197 412 WVSMLGMWGCRVVAGYTLGIVLGWGVVGVWLGMFFDWAVRAALFYWRMV 460
Cdd:cd13131 382 LLALISYWGIGLPLGYLLAFTTGLGAFGVWIGLIIGLALAAILLLWRFR 430
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
35-455 |
1.78e-31 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 125.51 E-value: 1.78e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 35 AVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAARQSLVI 114
Cdd:cd12082 1 AAPLLLSMLLQTLYNLVDTFFLGRLLGDALAAVGLAFPLIALLIALGVGLSVGTSALISQAIGAGDEEKARRVLVQSIVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 115 MTIFATVLAAVIHYFGQQIIDvvAGEATPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLLINGGMNILNI 194
Cdd:cd12082 81 AILLGLLLAALLLFFSPLILS--LLGAEEEVIELAATYLTILILGLPITFLGAVLSGILQGEGDTRTAMIISVLSNLLNI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 195 IISSILIYGIFSWqGLGFVGAGLGLTISRYIGAIAIIWVLmigFNPALRIPFKSYFKPLNLAIIWEVMGIGIPASIESVL 274
Cdd:cd12082 159 LLDPLLIFGLGPP-ELGIAGAALATVISYVIGALLLLIYL---RKGKKILKFKLSLLKPDLELLRRLLRIGLPSAIQNSL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 275 FNGGKLLTQMFVSG-MGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLSTIGLTAIA 353
Cdd:cd12082 235 LSLGLLIIVAIVAAfGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIGAVLG 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 354 WLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLGMWGCRVVAGYTLGiVL 433
Cdd:cd12082 315 LLILLFPEPILSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSLLSYWVVRLPLAYVLA-YL 393
|
410 420
....*....|....*....|..
gi 1476636197 434 GWGVVGVWLGMFFDWAVRAALF 455
Cdd:cd12082 394 GLGLYGIWLALVISLILAALVL 415
|
|
| MATE_like_14 |
cd13139 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
29-464 |
9.12e-28 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240544 [Multi-domain] Cd Length: 448 Bit Score: 115.40 E-value: 9.12e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 29 REITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAA 108
Cdd:cd13139 14 RAIFLLAIPMVLEMVMESLFAVVDLYFVSRLGALAIATVGLTESVLTIVYSIAIGLSMAATALVARRIGEKDPEGAGFAA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 109 RQSLVIMTIFATVLAAVIHYFGQQIIDVVAGEatPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPL----L 184
Cdd:cd13139 94 VQAILLGVALSLILSILGYFFAEDILSLMGAS--PAVIAEGYGYTRIMFGGNGFIMLLFLINGIFRGAGDAAIAMrslwL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 185 INGgmniLNIIISSILIYGIFSWQGLGFVGAGLGLTISRYIGAIAIIWVLMIGfnpALRIPFKSYFKPLNLAIIWEVMGI 264
Cdd:cd13139 172 ANG----LNIILDPLFIFGLGPIPAMGVTGAAIATTIGRSIGVLYQLYHLFKG---KGRIQIRRRHLKLDWAIIKKIIKI 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 265 GIPASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWL 344
Cdd:cd13139 245 AVGGILQFLIASSSWIFLVRIIAEFGSTALAGYTIAIRIIMFALLPAWGLSNAAATLVGQNLGAGQPDRAEKSVWRAGKY 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 345 STIGLTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLGMWGCRVV 424
Cdd:cd13139 325 NMVFLGIVSLVFFLFAEPLVSFFTTDPEVIAIAVEALRIISLGYIFYGYGMVLSQAFNGAGDTKTPTLINLVGFWLFQIP 404
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 1476636197 425 AGYTLGIVLGWGVVGVWLGMFFDWAVRAALFYWRMVTGRW 464
Cdd:cd13139 405 LAYLLARHLNLGPKGVFIAIPIAETVLAIAAIILFRRGKW 444
|
|
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
28-461 |
3.75e-25 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 107.26 E-value: 3.75e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 28 WREITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEA-MAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARA 106
Cdd:cd13136 2 HREILALALPAILSNITVPLLGLVDTAVVGHLGSAAyLGAVALGTTIFNTLFWLFGFLRMGTTGLVAQALGAGDREEAIA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 107 AARQSLVIMTIFATVLAAvihyFGQQIID--VVAGEATPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLL 184
Cdd:cd13136 82 LLVRALLLALAIGLLLIL----LQSPLLAlaLLLLGASAAVAALARQYLRIRILGAPAVLLNYVATGWFRGLQDTRTPLI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 185 INGGMNILNIIISSILIYGIfswqGLGFVGAGLGLTISRYIGAIAIIWVLMIGFNPALRIPFKSYFKPLNLAIIwevMGI 264
Cdd:cd13136 158 LQIVGNVVNIVLDPLFVFGL----GWGVAGAALATVIAQYLGALLGLWLLRRRVRLLGKSLSRRLPSKAALKRL---FKL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 265 GIPASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVF-- 342
Cdd:cd13136 231 NRDIFIRTLALLAAFLFFTALAARLGDVILAANQILLQFWLLSSYFLDGFAYAAEALVGRALGAGDRKAARRVARRLLqw 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 343 -WLSTIGLTAIAWLtapFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLGmwgc 421
Cdd:cd13136 311 gLGLGVLLALLFFL---GGEPIIRLFTDDPAVLALAATYLPWLALLPPIGALAFVLDGIFIGATDTRYLRNSMLVS---- 383
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 1476636197 422 rvVAGYTLGIVL---GWGVVGVWLGMFFDWAVRAALFYWRMVT 461
Cdd:cd13136 384 --LAVFLPLLFLlvpLWGNHGLWLALILFMLLRGLTLALRLPR 424
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
37-187 |
1.40e-21 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 91.09 E-value: 1.40e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 37 PIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAARQSLVIMT 116
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHLGAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILGL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1476636197 117 IFATVLAAVIHYFGQQIIDVVAGEatPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLLING 187
Cdd:pfam01554 81 LLSLPIALLVLLFSEPILSLFGQD--EEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINI 149
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
29-458 |
8.23e-21 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 94.67 E-value: 8.23e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 29 REITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAA 108
Cdd:cd13135 1 KKINHIAIPLILQNLVSQLQMLVDRAFLGRISIRYYSAVGNVTTPFNTITGFLGSISIGFTILGSQSVGAKDIKRINDYA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 109 RQSLVIMTIFAtVLAAVIHYFGQQIIDVVAGeATPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKiPLLINGG 188
Cdd:cd13135 81 ISSIVYNSIIG-VILFLLWLFGARIIFVLFG-VDGQILGYSINYVRIFSIYLLLLGILFTFSSILQGIGETK-PIMYGGI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 189 MNILN-IIISSILIYGIFSWQGLGFVGAGLGLTISRYIGAIAIIWVLM----IGFNPALRIPFKSYFKPLNLAIiwevmG 263
Cdd:cd13135 158 IKNLLnVILDYVLIFGNFGFPRLGIIGAAIATTIANVLNLIILVYLCRkikkLTFKLSNTKVLKANIRPYKFTI-----K 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 264 IGIPASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFW 343
Cdd:cd13135 233 LGLPLGGEEFLWNIGNLAVIRILNRIGELALGIYTLVFGIENIVLMPMYGYSSAALTLVGESIGKKDLKEALRIGNICLG 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 344 LSTIGLTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFaMWVSMLGMWGCRV 423
Cdd:cd13135 313 LGLLIYIAAAIVFLAFPYKILSLFTNDPELINYSIPYLIFIIIILFFKSINIVYGFAIRAIGDTKW-MLYTQIIGTIIVV 391
|
410 420 430
....*....|....*....|....*....|....*
gi 1476636197 424 VAGYTLGIVLGWGVVGVWLGMFFDWAVRAALFYWR 458
Cdd:cd13135 392 SVALLLIFVFKLGLAGVYITLFIDEIIRAIINFLK 426
|
|
| MATE_MJ0709_like |
cd13147 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, ... |
34-444 |
1.78e-19 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, similar to Methanocaldococcus jannaschii MJ0709; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240552 [Multi-domain] Cd Length: 441 Bit Score: 90.68 E-value: 1.78e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 34 LAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAARQSLV 113
Cdd:cd13147 14 LSIPMIIAMLLQTLYNLVDAIWVAGLGADALAAIGFVFPLFMIIIGLGNGLGAGASSAISRRIGAKDKEGADNAAVHSIL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 114 IMTIFATVLAAVIHYFGQQIIDVVAGEatpDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLLINGGMNILN 193
Cdd:cd13147 94 LGLIISIILTIVLLPFLEPILVLMGAG---EVLDLAVDYGRIIFLGSIFLIFNNVAYGILRGEGDTKRAMYAMVAGSILN 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 194 IIISSILIYGIfswqGLGFVGAGLGLTISRYIGAIAIIWVLMIGFNPALRIPFKsYFKPlNLAIIWEVMGIGIPASIE-- 271
Cdd:cd13147 171 IILDPIFIYTL----GLGIAGAAWATVISMLISSLVLLYWFFVKKDTYVSLSLK-NFKF-DKKIVKDILKVGIPASLEql 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 272 --SVLFnggKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLSTIGL 349
Cdd:cd13147 245 imSVLM---IILNLILVIVAGTDGVAVYTAGWRIVSFAIIPLIGIATAVTSVTGAAYGARNYEKLKTAYNYSIKLGLIIE 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 350 TAIAWLTAPFAGVMASFYTHDQDVKEVIVILI-WLNAA--FMPIWAASWVLPAGFKGARDARFAMWVSMLGMWGCRVVAG 426
Cdd:cd13147 322 LIIAILIFIFAPQIAYLFTYSEESAHLAPEIVaFLRIMclFLPFVPFGMMSSSMFQGIGKGLTSLIITILRELIFQVLFA 401
|
410
....*....|....*...
gi 1476636197 427 YTLGIVLGWGVVGVWLGM 444
Cdd:cd13147 402 YLFAIVLGLGLFGVWWGI 419
|
|
| MATE_like_2 |
cd13149 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
28-382 |
1.67e-18 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240554 [Multi-domain] Cd Length: 434 Bit Score: 87.74 E-value: 1.67e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 28 WREITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAA 107
Cdd:cd13149 8 PRHLIKLTLPMIFGILAMLIFNLTDTFFVGKLGTKELAAISFTFPVVLFLNSLTIGLGIGASAVISRAIGAGDRNKAKRL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 108 ARQSLVIMTIFATVLAAVIHYFGQQIIDVVAgeATPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLLING 187
Cdd:cd13149 88 ATDSLILSLLLSVIVSLLGLFTIPPLFSLLG--ASGEILPLIVEYMAIWYLGLVFLVLPMVGNAIIRATGDTKRPSLVML 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 188 GMNILNIIISSILIYGIFSWQGLGFVGAGLGLTISRYIGAIAIIWVLMigFNPALRIPFKSYFKPLNLAIIwEVMGIGIP 267
Cdd:cd13149 166 GAALVNVILDPILIFGFGPIPGMGIAGAAIATVISRALGLGAALYFLH--YHHRLIDFSEPSLKALFRSWK-DILSIGIP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 268 ASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLSTI 347
Cdd:cd13149 243 AALSNILTPLSAAFITALVATYGPAAVAAFGVATRIESFAFIIVMALSSALGPFVGQNWGAGQYERVQEGLKISLKFSLI 322
|
330 340 350
....*....|....*....|....*....|....*
gi 1476636197 348 GLTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIW 382
Cdd:cd13149 323 YGAILGIVLALFAGWLASLFSAEPEVIELITLYLL 357
|
|
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
26-444 |
1.44e-17 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 84.48 E-value: 1.44e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 26 LFWReitpLAVPIFLENTCVLLMGVLSTFLVS-WLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRA 104
Cdd:cd13143 5 LFLK----FALPAIIGMLVNGLYNIVDGIFVGhGVGALALAAVNLVFPIIMLLMALGLMIGVGGASLISRRLGAGDREKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 105 RAAARQSLVIMTIFATVLAAVIHYFGQQIIDVVAgeATPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLL 184
Cdd:cd13143 81 NRIFSTALLLSLILGLLLTILGLLFLDPLLRLLG--ASGELLPYAVDYLRIILLGAPFTILSSVLNNLLRAEGKPKLAML 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 185 ingGMNILNIIISSILIYGIFSWqGLGFVGAGLGLTISRYIGAIAIIWVLMIGfnpALRIPFKSYFKPLNLAIIWEVMGI 264
Cdd:cd13143 159 ---GMLIGAVLNIILDPLFIFVL-GLGIAGAALATVIAQLISLLLLLLYFFRG---KSLLKLSLLRFKLSLKIIKEILAL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 265 GIPASIESVLFN-GGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFW 343
Cdd:cd13143 232 GFPSFLMQLSSSvVTIVLNLTLLGYGGDIGVAAFGIVTRILTFLFLPLIGLSQGLQPIIGYNYGAGNYDRVKQALKLALI 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 344 LSTIGLTAIAWLTAPFAGVMASFYTHDQDV-KEVIVILIWLNAAFmPIWAASWVLPAGFKGARDARFAMWVSMLGMWGCR 422
Cdd:cd13143 312 VALIYGLVLFLILLLFPEQIVSLFTDDPELiALAARILRIFLLAF-PLAGINIVLSGYFQAIGKAKRAALLSLLRQGLFL 390
|
410 420
....*....|....*....|..
gi 1476636197 423 VVAGYTLGIVlgWGVVGVWLGM 444
Cdd:cd13143 391 IPLLLILPRL--FGLDGIWLAF 410
|
|
| MATE_like_5 |
cd13145 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
34-457 |
2.33e-16 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240550 [Multi-domain] Cd Length: 440 Bit Score: 81.10 E-value: 2.33e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 34 LAVPI---FLENTcvlLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAARQ 110
Cdd:cd13145 14 LAIPAsvgFFFNT---MFNVVDTFFAGKISTEALAALSLSFPIFFIIIAIGVGIGTGTTALIGNALGAGDRRKARRYAAQ 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 111 SLVIMTIFATVLAAVIHYFGQQIIDVVAgeATPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTK-------IPL 183
Cdd:cd13145 91 GLSFGIILAILLTVIGLFAAPPLFRLLG--AEGDYLDLALEYMDVIFAGSIFFLLNFGLNGILNAQGDTKsyrnfliIGF 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 184 LINggmnilnIIISSILIYGIFSWQGLGFVGAGLGLTISRYIGAIAIIWVLMIGFNPALRIPfkSYFKPlNLAIIWEVMG 263
Cdd:cd13145 169 FLN-------IILDPLFIFGGGGIPAMGVSGIALATIISQFIGMFYLLYKVRKSGIISGCRL--RDFIP-RLDVYKEILK 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 264 IGIPASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQ---IAQAEIQ-LR 339
Cdd:cd13145 239 QGFPASLNMMTIGLGIFVITYFVGQFGDEAVAAYGIALRIEQILLLPTIGLNTAVLSIAGQNFGAKKydrVRETYKKaLK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 340 HVFWLSTIGlTAIAWLTAPFAgvmASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLgmw 419
Cdd:cd13145 319 YGFVIMVVA-TVFLLFFAEPL---MSLFTNDPAVIAIGAGYLRIDALIFYAYVVLFISVSVLQGLKRPIFALWIGLY--- 391
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 1476636197 420 gcRVVAG-----YTLGIVLGWGVVGVWLGMFFDWAVRAALFYW 457
Cdd:cd13145 392 --RQLVGpalvfWLLVNVLGLGVTGIWWGIFTIVWSAAIIALL 432
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
53-444 |
5.63e-16 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 79.88 E-value: 5.63e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 53 TFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAARQSLVIMTIFATVLAAVIHYFGQQ 132
Cdd:cd13140 29 MFWVGRLGSDAVAAVGTAGFFVWLAYALALLSKIGAQVKVSQSIGAKDEKEARKYARNALQLNLLLGILYGLLLLLFAKP 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 133 IIDVVAGEAtPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLLINGGMNILNIIISSILIYGIFSWQGLGF 212
Cdd:cd13140 109 LIGFFNLGD-AEVISLAITYLRIVALGLIFSFLNPVFTGIFNALGDSKTPFIINAIGLVLNIILDPLLIFGFGPFPALGV 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 213 VGAGLGLTISRYIGAIAIIWVLMIGFNPALRIPFksyFKPLNLAIIWEVMGIGIPASIESVLFNGGKLLTQMFVSGMGTS 292
Cdd:cd13140 188 AGAALATVLAQAIVFLLFLYALKKKKGLFLKIRI---LKRPDRKYIKEILKLGLPVALQSILFALISMILARIIASFGPV 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 293 VIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLSTIGLTAIAWLTAPFAGVMASFYTHDQD 372
Cdd:cd13140 265 AIAAQKVGSQIESISWMTAEGFSTALAAFVGQNYGAGKYDRIRKGYKTALKIASAIGLFATLLLFFFGEPLFSLFIPDPE 344
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1476636197 373 VKEV-IVILIWLNAA--FMPIWAASwvlpAG-FKGARDARFAMWVSMLGMwGCRVVAGYTLGIvLGWGVVGVWLGM 444
Cdd:cd13140 345 TIAIgVDYLRILGFSqlFMCLEITT----TGaFNGLGRTKPPAIISIVFN-GLRIPLALLLSP-TGLGLNGIWWAI 414
|
|
| PRK01766 |
PRK01766 |
multidrug efflux protein; Reviewed |
28-469 |
2.91e-15 |
|
multidrug efflux protein; Reviewed
Pssm-ID: 234981 [Multi-domain] Cd Length: 456 Bit Score: 77.93 E-value: 2.91e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 28 WREITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAA 107
Cdd:PRK01766 11 ARQLLALALPILLAQVAQTAMGFVDTVMAGGVSATDLAAVAIGTSIWLPVILFGHGLLLALTPIVAQLNGAGRRERIAHQ 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 108 ARQSLVIMTIFATVLAAVIhYFGQQIIDVVAGeATPDVKALALTYLELTVLsypaAAIALIGSGALR----GAGNTKIPL 183
Cdd:PRK01766 91 VRQGLWLALFLSVLIMLVL-YNAVPPILNMMN-LEPEVADIAVGYLHALLW----GIPAYLLYQVLRsfidGLGKTKPTM 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 184 LINGGMNILNIIISSILIYGIFSWQGLGFVGAGLGLTISRYIGAIAIIWVLMIGFNPALRIPFKSYFKPlNLAIIWEVMG 263
Cdd:PRK01766 165 VIGFLGLLINIPLNYIFIYGKFGFPELGGVGCGVATAIVYWVMFLAMLIYIKRARRFRDFRLFKGLYKP-DWAVIKRLLK 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 264 IGIPASIeSVLFNGGKL-LTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEiQLRHVF 342
Cdd:PRK01766 244 LGLPIGL-AIFFEVSLFaVVTLLVSPLGTVTVAAHQIALNFSSLLFMLPLSLAMALTIRVGFELGAGRTLDAR-QYAYIG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 343 WLSTIGLTAI-AWLTAPFAGVMASFYTHDQDVKEVIVILIwLNAAFMPIWAASWVLPAG-FKGARDARFAMWVSMLGMWG 420
Cdd:PRK01766 322 LAVGLGMALLtAIFLVLFREQIALLYTDDPEVVALASHLL-LFAALFQFSDAIQVIGSGaLRGYKDTRVIFFITFIAYWV 400
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 1476636197 421 CRVVAGYTLGIVLGWGVVGVWLGMFFDWAVRAALFYWRMvtgRWLWKYP 469
Cdd:PRK01766 401 LGLPLGYILALTDPMGPFGFWIGLIIGLTAAAILLLLRL---RKLQRQP 446
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
267-418 |
9.27e-13 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 66.05 E-value: 9.27e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 267 PASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLST 346
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHLGAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILGL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1476636197 347 IGLTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLGM 418
Cdd:pfam01554 81 LLSLPIALLVLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISL 152
|
|
| MATE_like_13 |
cd13141 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
29-376 |
2.96e-12 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240546 [Multi-domain] Cd Length: 443 Bit Score: 68.50 E-value: 2.96e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 29 REITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAA 108
Cdd:cd13141 11 KHIISMALPIAIGMIIQTLYFLVDLYFVGQLGDAALAGVSLAGNVMFFVMALTQVLNVGTAALVSHAVGRKDQGEANAVF 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 109 RQSLVIMTIFATVLAAVIHYFGQQIIDVVAGEATpdVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLLINGG 188
Cdd:cd13141 91 NQSLLLAAVLGLVVLVLGYLFGRLYLETLAADAA--TVEAATTYLYWFIPSLALQFILTVLGAALRGTGIVKPFMVIQIL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 189 MNILNIIISSILIYGIFSWQGLGFVGAGLGLTISrYIGAIAIIWVLMIGFNPALRIPFKSyFKPlNLAIIWEVMGIGIPA 268
Cdd:cd13141 169 AVLLNIILAPILITGWGTGRALGVAGAGLASSIS-VAIAVVLLLYYFLRLEKYLRLDLAL-WRP-DLPTWKRLLKIGLPS 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 269 SIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLSTIG 348
Cdd:cd13141 246 GGEFLLTFVYMAVIYWALRPFGAAAQAGFGIGSRIMQSLFLPAMAIAFAAPAIAGQNFGAGNYDRVRETFRITAILTTAL 325
|
330 340
....*....|....*....|....*...
gi 1476636197 349 LTAIAWLTAPFAGVMASFYTHDQDVKEV 376
Cdd:cd13141 326 MLVLTLLCQLVPELLVTPFSDDAAVIAV 353
|
|
| MATE_like_3 |
cd13148 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
34-335 |
6.02e-12 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240553 [Multi-domain] Cd Length: 441 Bit Score: 67.30 E-value: 6.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 34 LAVP---IFLENTCVllmGVLSTFLVSWLGKEAMAGVGLADSFNMVI-MAFFAAIDLGTTVVVAFSLGKRDRRRARAAAR 109
Cdd:cd13148 17 LALPnilALLVQTLV---GLAETYFVGQLGTDALAGVALVFPLLMLTqMMSNGAMGGGVSSAIARALGAGDRERAEALVW 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 110 QSLVIMTIFATVLAAVIHYFGQQIIDVVAGEAtpDVKALALTYLEltVLSYPAAAIALIG--SGALRGAGNTKIPLLING 187
Cdd:cd13148 94 HALVIALAGGLVFSLLFLLFGPALYRLLGGRG--EALDAALAYSN--VLFSGAILIWLVNllAAALRGTGNMRVPALVTL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 188 GMNILNIIISSILIYGIFSWQGLGFVGAGLGLTISRYIGAIAIIWVLMIGFNpalRIPFKSYFKPLNLAIIWEVMGIGIP 267
Cdd:cd13148 170 VGAVVQIPLSPGLILGWGPLPRLGVAGAAVAAVLYYALAALVLLRYLASGRS---RLRLRLRALRLERRLFRDILRVGLL 246
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1476636197 268 ASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAE 335
Cdd:cd13148 247 AALSPLQTNLTVLLLTGLVGRFGTAALAGYGIGSRLEFLLIPLVFGLGAAMTAMVGMNIGAGQIARAR 314
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
257-471 |
1.50e-11 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 65.94 E-value: 1.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 257 IIWEVMGIGIPASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEI 336
Cdd:COG0534 6 ILKLLLRLALPIILGNLLQSLYGLVDTIFVGRLGTAALAAVGLAFPIFFLLIALGIGLGVGGTALVAQALGAGDREEARR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 337 QLRHVFWLSTIGLTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSML 416
Cdd:COG0534 86 VLGQALLLALLLGLLLTLLGLLFAPPLLRLLGADPEVLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTPMIIMLI 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1476636197 417 GMwGCRVVAGYTLGIVLGWGVVGVWLGMFFDWAVRAALFYWRMVTGRWLWKYPRP 471
Cdd:COG0534 166 GN-VLNIVLDPLLIFGGGLGVAGAALATVISQAVSALLLLYYLFRKRSLLRLRLR 219
|
|
| MATE_eukaryotic |
cd13132 |
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral ... |
29-446 |
3.19e-11 |
|
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. This subfamily, which is restricted to eukaryotes, contains vertebrate solute transporters responsible for secretion of cationic drugs across the brush border membranes, yeast proteins located in the vacuole membrane, and plant proteins involved in disease resistance and iron homeostatis under osmotic stress.
Pssm-ID: 240537 [Multi-domain] Cd Length: 436 Bit Score: 65.29 E-value: 3.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 29 REITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVImAFFAAIDLGTTV--VVAFSLGKRDRRRARA 106
Cdd:cd13132 3 KKLLRLAAPLVLTSLLQYSLSVVSVVFVGHLGKLELAAASLASSFANVT-GFSILLGLASALdtLCGQAFGAKNYKLVGV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 107 AARQSLVIMTIFATVLAAVI-------HYFGQqiidvvageaTPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNT 179
Cdd:cd13132 82 YLQRALVILLLCCVPISLLWlntepilLLLGQ----------DPEIARLAGEYLRWLIPGLFAYALFEPLKRYLQAQGIV 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 180 KIPLLINGGMNILNIIISSILIYGIfswqGLGFVGAGLGLTISRYIGAIA-IIWVLMIGFNPALRIPFKSyfkpLNLAII 258
Cdd:cd13132 152 LPLVYISLVALLLNILLNYLLVFVL----GLGFIGAALATSISYWLIVVLlLLYIFFSKGHKATWGGFSR----EAFRGW 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 259 WEVMGIGIPASI----ESVLFNGGKLLTQMFVsgmGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQA 334
Cdd:cd13132 224 GPFLKLAIPSALmlclEWWAFEILVLLAGLLP---GTVALAAQSICLTTTSLLYMIPLGISIAASVRVGNELGAGNPKRA 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 335 EIQLRHVFWLSTIGLTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVS 414
Cdd:cd13132 301 KLAAIVALILSLVIGVVVAILLLVLRDVWAYLFTSDEEVIALVADLLPILALFQIFDGLQAVLSGVLRGCGRQKLGAYVN 380
|
410 420 430
....*....|....*....|....*....|..
gi 1476636197 415 MLGMWGCRVVAGYTLGIVLGWGVVGVWLGMFF 446
Cdd:cd13132 381 LVAYYLIGLPVGLLLAFVLGLGLKGLWIGLIA 412
|
|
| MATE_like_6 |
cd13146 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
34-460 |
8.62e-11 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240551 [Multi-domain] Cd Length: 433 Bit Score: 63.57 E-value: 8.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 34 LAVPIFLENTCVLLMGVLSTFLVSWLGKEA---MAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAARQ 110
Cdd:cd13146 13 LALPILIGQLFQLLYNITDTIWISMIDPSDpalVGGIGLVFPLGMIFLALGNGIQVGVSSLLARAIGAQRAKELDQAADS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 111 SLVIMTIFATVLAAVIHYFGQQIIDVVAGEATPDVKALALTYLELTVLSYPAAAIALIgsGALRGAGNTKIpllINGGMN 190
Cdd:cd13146 93 GLALALLAATVIVVLGYIFAEPLLQLLGAKGLLLEYALEYFYYSLPGVPFIMLIGVLM--GVLQGEGRTKY---MMMAML 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 191 ILNIIISSILIYGIFSWqGLGFVGAGLGLTISRYIGAIAIIWVLMIGfnpALRIPFKSYFKPLNLAIIWEVMGIGIPASI 270
Cdd:cd13146 168 IGTVVNIVLDPILIFVF-DMGVKGAALATVLAQAISLLYLLYVFLIG---KSNVTIHIKLSNISSSVIVEILRVGLPQML 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 271 ESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLSTIGLT 350
Cdd:cd13146 244 LQLISSISFLIYNRIIIDIDPVAMTAFTLVGRLDQFILIPIFAISSALLTIAGQNWGRGNYDRMLQILMTAVILGIVVVL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 351 AIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLGMWGCRVVAGYTLG 430
Cdd:cd13146 324 VLVLGYVLVAPWLFSLFTTVPEVVAYAVLQVRTMALALPFVAISILVTEFFQAIGKAWPSLLLTLIRHVFLSVPVVYLLA 403
|
410 420 430
....*....|....*....|....*....|
gi 1476636197 431 IVLGWGVVGVWLGMFFDwAVRAALFYWRMV 460
Cdd:cd13146 404 YVFGKGITGVYFGIVSA-NFFTALLAMFWG 432
|
|
| MATE_like_4 |
cd13144 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
29-442 |
3.69e-05 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240549 [Multi-domain] Cd Length: 434 Bit Score: 46.07 E-value: 3.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 29 REITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAA 108
Cdd:cd13144 8 RLLLTMSIPAMISMLFQALYNIVDSIFVARLGENALTAVSLAFPIQNLMIAVAVGTGVGVNALLSRSLGEKDQKEANKAA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 109 RQSLViMTIFATVLAAVIHYFGQQIIdVVAGEATPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLLINGG 188
Cdd:cd13144 88 NNGLL-LALLSYLLFLLLGLFGVKPF-FRLFTDDPEILEYGYAYLSWCVIFSFGMFFQILCEKVLQSTGNTITPMIAQLI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 189 MNILNIIISSILIYGIFSWQGLGFVGAGLGLTISRYIGAIaIIWVLMIGFNPAlrIPFKSYFKPLNLAIIWEVMGIGIPA 268
Cdd:cd13144 166 GAIINIILDPILIFGLFGFPAMGIAGAAIATVIGQILAMF-LAFFFLLRKNKD--VQPDLRLFRPSLRIIKEIYAVGLPS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 269 SIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLSTIG 348
Cdd:cd13144 243 IIMQAISSVMVFGLNKILAGFGPTAVAVFGIYFKLQSFVFMPVFGLNNGLIPIVAYNYGAGNKDRIREAIKYAILIAVVI 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 349 LTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLGMWGCRVVAGYT 428
Cdd:cd13144 323 MLAGGLLFQLFPDQLLGLFNASEEMLAIGVPALRIISLSFLFAALSIILSGLFQALGRGVYSLIISVARQLVVLLPLAWL 402
|
410
....*....|....
gi 1476636197 429 LGivLGWGVVGVWL 442
Cdd:cd13144 403 LA--KMFGLNGVWW 414
|
|
| PRK00187 |
PRK00187 |
NorM family multidrug efflux MATE transporter; |
204-482 |
1.22e-04 |
|
NorM family multidrug efflux MATE transporter;
Pssm-ID: 166843 [Multi-domain] Cd Length: 464 Bit Score: 44.35 E-value: 1.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 204 IFSWQGLGFVG-AGLGLTISRYIGAIAIIWVLMIGFNPALRI-PFKSYFKPLNLAIIWEVMGIGIPA----SIESVLFNG 277
Cdd:PRK00187 179 IEGWFGLPKLGlMGIGLVTALVSNGMALALALYIRRHPAYAAyPLRKGLSRPSRAALRELWRLGLPIggtyAVEVGLFTF 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 278 GKLLtqmfVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLSTIGLTAIAWLTA 357
Cdd:PRK00187 259 AALC----MGALGSTQLAAHQIALQIVSVAFMVPVGLSYAVTMRVGQHYGAGRLLEARRAGRVGIGFGAVVMLLFAGLFW 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 358 PFAGVMASFYTHDQD-----VKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLGMWGCRVVAGYTLGIV 432
Cdd:PRK00187 335 LLPEAIIGLFLDRNDpafaeIVQLAVSLLAVAAWFELFDGTQTIAMGAIRGLKDARTTFLIGLACYWLVGAPLAWLLAFT 414
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1476636197 433 LGWGVVGVWLGMFFDWAVRAALFYWRMVtgrwlWKYPRPEREKCIKQPVA 482
Cdd:PRK00187 415 LGWGAVGVWWGLALGLACAAVALTLAFE-----WKTARLLRKARASEAVA 459
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
266-464 |
1.67e-04 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 43.85 E-value: 1.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 266 IPASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLS 345
Cdd:cd12082 2 APLLLSMLLQTLYNLVDTFFLGRLLGDALAAVGLAFPLIALLIALGVGLSVGTSALISQAIGAGDEEKARRVLVQSIVLA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 346 TIGLTAIAWLTAPFAGVMASFYTHDQDVKEVIVILIWLNAAFMPIWAASWVLPAGFKGARDARFAMWVSMLG-------- 417
Cdd:cd12082 82 ILLGLLLAALLLFFSPLILSLLGAEEEVIELAATYLTILILGLPITFLGAVLSGILQGEGDTRTAMIISVLSnllnilld 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1476636197 418 -----MWGCRV--VAGYTLGIVLGWGVVGVWLGMFFDWAVRAALFYWRMVTGRW 464
Cdd:cd12082 162 pllifGLGPPElgIAGAALATVISYVIGALLLLIYLRKGKKILKFKLSLLKPDL 215
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
267-417 |
1.68e-04 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 43.77 E-value: 1.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 267 PASIESVLFNGGKLLTQMFVSGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGRRLGNGQIAQAEIQLRHVFWLST 346
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHLGPVDLAAVSLGSSVFMFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLLLAL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1476636197 347 IGLTAIAWLTAPFAGVMASFYTHDQDVKEV----IVILIWlnaaFMPIWAASWVLPAGFKGARDARFAMWVSMLG 417
Cdd:TIGR00797 81 LLGLPVLLVGYFFIDPLLSLMGADGEVAELaqdyLRILIL----GIPAYLLNFVLRGFLRGQGDTKTPMYITLIG 151
|
|
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
7-180 |
8.17e-03 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 38.70 E-value: 8.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 7 LRQVASRTPWYAKRKSYKVLFWREITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDL 86
Cdd:cd13136 203 LRRRVRLLGKSLSRRLPSKAALKRLFKLNRDIFIRTLALLAAFLFFTALAARLGDVILAANQILLQFWLLSSYFLDGFAY 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 87 GTTVVVAFSLGKRDRRRARAAARQSLVIMTIFATVLAAVIHYFGQQIIDVVAGEatPDVKALALTYLELTVLSYPAAAIA 166
Cdd:cd13136 283 AAEALVGRALGAGDRKAARRVARRLLQWGLGLGVLLALLFFLGGEPIIRLFTDD--PAVLALAATYLPWLALLPPIGALA 360
|
170
....*....|....
gi 1476636197 167 LIGSGALRGAGNTK 180
Cdd:cd13136 361 FVLDGIFIGATDTR 374
|
|
| MATE_like_2 |
cd13149 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
28-234 |
8.17e-03 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240554 [Multi-domain] Cd Length: 434 Bit Score: 38.44 E-value: 8.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 28 WREITPLAVPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAA 107
Cdd:cd13149 233 WKDILSIGIPAALSNILTPLSAAFITALVATYGPAAVAAFGVATRIESFAFIIVMALSSALGPFVGQNWGAGQYERVQEG 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1476636197 108 ARQSLVIMTIFATVLAAVIHYFGQQIIDVVAGEatPDVKALALTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLLING 187
Cdd:cd13149 313 LKISLKFSLIYGAILGIVLALFAGWLASLFSAE--PEVIELITLYLLIVPIGYGGLGILIITSASFNALGKPLYSLGLNL 390
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1476636197 188 GmnilniiiSSILIYGIFSWQG---LGFVGAGLGLTISRYIGAIAIIWVL 234
Cdd:cd13149 391 I--------RVFLLYIPLAYVGshlLGFAGVFIGALAGNLIAGILAYFIA 432
|
|
|