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transporter [Bordetella pertussis]
Protein Classification
monovalent cation:proton antiporter-2 (CPA2) family protein ( domain architecture ID 1004960 )
monovalent cation:proton antiporter-2 (CPA2) family protein such as glutathione-regulated potassium-efflux system protein, which facilitates potassium-efflux, possibly by potassium-proton antiport
List of domain hits
Name
Accession
Description
Interval
E-value
PRK03562 super family
cl35207 glutathione-regulated potassium-efflux system protein KefC; Provisional
6-372
1.82e-111
glutathione-regulated potassium-efflux system protein KefC; Provisional
PRK03562 :Pssm-ID: 235131 [Multi-domain]
Cd Length: 621
Bit Score: 339.66
E-value: 1.82e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 6 I L L I AAVL C VP L A Q RLGLG AIP GYL L AG GV IGP S GL G LVTDV PD I MRVS E W GVV M MLFVIGLEL A P K RLW AM RR EV FG A G 85
Cdd:PRK03562 12 I Y L G AAVL I VP I A V RLGLG SVL GYL I AG CI IGP W GL R LVTDV ES I LHFA E F GVV L MLFVIGLEL D P Q RLW KL RR SI FG G G 91
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 86 T LQMV V CG A LLG AVFGA glrhl A G MG WQ A A I L C GL S LALSSTA V A LRLLE ER G L VR T PL GRSA LGV LL L QD M AAIP MLVA 165
Cdd:PRK03562 92 A LQMV A CG G LLG LFCML ----- L G LR WQ V A L L I GL G LALSSTA I A MQAMN ER N L MV T QM GRSA FAI LL F QD I AAIP LVAM 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 166 AG LL GSD G D S APSFEA AL V A VV V VL A C -------- Y RL R - L L DWA ARS Q L H E L FTA AT L LV V L G TAQ L FDYA GLS AG LG G 236
Cdd:PRK03562 167 IP LL AAS G A S TTLGAF AL S A LK V AG A L alvvlggr Y VT R p A L RFV ARS G L R E V FTA VA L FL V F G FGL L MEEV GLS MA LG A 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 237 FL V G M LLA E S RH R NE LE HT IEPFKGLLLGLFF L AVGMS VNVEEA L DYWPYV L AGVVAL L SL K ALV L YGI AR LM G L P HYH R 316
Cdd:PRK03562 247 FL A G V LLA S S EY R HA LE SD IEPFKGLLLGLFF I AVGMS IDFGTL L ENPLRI L ILLLGF L AI K IAM L WLL AR PL G V P RKQ R 326
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1551827355 317 LLY A LV L A QGGEF S FV I F NE A WDNHLMSL E QRD LL AIV VA I SM G A V P IVIR LL E RL 372
Cdd:PRK03562 327 RWF A VL L G QGGEF A FV V F GA A QMANVLEP E WAK LL TLA VA L SM A A T P LLLV LL D RL 382
Name
Accession
Description
Interval
E-value
PRK03562
PRK03562 glutathione-regulated potassium-efflux system protein KefC; Provisional
6-372
1.82e-111
glutathione-regulated potassium-efflux system protein KefC; Provisional
Pssm-ID: 235131 [Multi-domain]
Cd Length: 621
Bit Score: 339.66
E-value: 1.82e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 6 I L L I AAVL C VP L A Q RLGLG AIP GYL L AG GV IGP S GL G LVTDV PD I MRVS E W GVV M MLFVIGLEL A P K RLW AM RR EV FG A G 85
Cdd:PRK03562 12 I Y L G AAVL I VP I A V RLGLG SVL GYL I AG CI IGP W GL R LVTDV ES I LHFA E F GVV L MLFVIGLEL D P Q RLW KL RR SI FG G G 91
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 86 T LQMV V CG A LLG AVFGA glrhl A G MG WQ A A I L C GL S LALSSTA V A LRLLE ER G L VR T PL GRSA LGV LL L QD M AAIP MLVA 165
Cdd:PRK03562 92 A LQMV A CG G LLG LFCML ----- L G LR WQ V A L L I GL G LALSSTA I A MQAMN ER N L MV T QM GRSA FAI LL F QD I AAIP LVAM 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 166 AG LL GSD G D S APSFEA AL V A VV V VL A C -------- Y RL R - L L DWA ARS Q L H E L FTA AT L LV V L G TAQ L FDYA GLS AG LG G 236
Cdd:PRK03562 167 IP LL AAS G A S TTLGAF AL S A LK V AG A L alvvlggr Y VT R p A L RFV ARS G L R E V FTA VA L FL V F G FGL L MEEV GLS MA LG A 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 237 FL V G M LLA E S RH R NE LE HT IEPFKGLLLGLFF L AVGMS VNVEEA L DYWPYV L AGVVAL L SL K ALV L YGI AR LM G L P HYH R 316
Cdd:PRK03562 247 FL A G V LLA S S EY R HA LE SD IEPFKGLLLGLFF I AVGMS IDFGTL L ENPLRI L ILLLGF L AI K IAM L WLL AR PL G V P RKQ R 326
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1551827355 317 LLY A LV L A QGGEF S FV I F NE A WDNHLMSL E QRD LL AIV VA I SM G A V P IVIR LL E RL 372
Cdd:PRK03562 327 RWF A VL L G QGGEF A FV V F GA A QMANVLEP E WAK LL TLA VA L SM A A T P LLLV LL D RL 382
KefB
COG0475 Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism]; ...
4-375
7.86e-81
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism];
Pssm-ID: 440243 [Multi-domain]
Cd Length: 384
Bit Score: 253.15
E-value: 7.86e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 4 L TI LL I AAVL CVP LA Q RLGL GAIP GY L LAG GVI GPSGLGL VT D VPDIMRVS E W GVV MM LF V IGLEL AP KRL WA M R R EVF G 83
Cdd:COG0475 9 L GL LL L AAVL AGL LA R RLGL PSVL GY I LAG ILL GPSGLGL IE D SEALELLA E L GVV LL LF L IGLEL DL KRL RK M G R RAL G 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 84 A G T LQ MVVCGA L LGAVF gaglr H L A G MGWQ AA ILC G LS LA LS STA VA L RL L E E R GL VR TPLG RSA LGV L L LQ D M AAI PM L 163
Cdd:COG0475 89 I G L LQ VLLPFL L GFLLA ----- L L L G LSLA AA LFL G AA LA AT STA IV L KV L K E L GL LK TPLG QLI LGV A L FD D I AAI LL L 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 164 - VAAG L L G SDGDSAPSFE A A L V A VVVVLACYRL ------ RL LDWA AR SQLH ELF TAAT LL V VL GT A Q L FDYA GLSA G LG G 236
Cdd:COG0475 164 a LVPA L A G GGSVAGSLLL A L L K A LLFLALLLLV gryllr RL FRLV AR TRSR ELF LLFA LL L VL LA A A L AELL GLSA A LG A 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 237 FL V G ML LAES RH R N ELE HT IEPF KG L L L G LFF LA VG M S VNVEEA L DYWPYV L AG V V A LLSL K A L VL Y GI ARL M GL PHYHR 316
Cdd:COG0475 244 FL A G LV LAES EY R H ELE EK IEPF GD L F L P LFF VS VG L S LDLSAL L SNPLLA L LL V L A AIVG K L L GA Y LA ARL F GL SRREA 323
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1551827355 317 L LYA L V LA QG GEF SF V IFNEAWDNH L M S L E QRDL L AI VV AISMGAV P IVI RL LE RL PG R 375
Cdd:COG0475 324 L RIG L L LA PR GEF AL V LASLGLSAG L I S P E LFAA L VL VV LLTTLLT P LLL RL AL RL AE R 382
2a37
TIGR00932 transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding ...
8-276
6.59e-59
transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273348 [Multi-domain]
Cd Length: 273
Bit Score: 193.25
E-value: 6.59e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 8 L I AAVL C VPL AQ RLG LGAIP GYLLAG GV IGPSGLGL VTD V PDIMRVS E W GV VMML F V IGLEL APK RLW AM R REV FG A G T L 87
Cdd:TIGR00932 1 L L AAVL A VPL SR RLG IPSVL GYLLAG VL IGPSGLGL ISN V EGVNHLA E F GV ILLM F L IGLEL DLE RLW KL R KAA FG V G V L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 88 Q MV V C G A LL gavf G AG L R HL A G MGWQ AA ILC G LS LALSSTAV ALRL L E ERGL VR TP L G RSA LG V LL L QD M A AI P M L VAAG 167
Cdd:TIGR00932 81 Q VL V P G V LL ---- G LL L G HL L G LALG AA VVI G II LALSSTAV VVQV L K ERGL LK TP F G QTV LG I LL F QD I A VV P L L ALLP 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 168 LL GS d GD S APSFEA AL VAVV V V LA CYR L R LL --------- DWA A RSQLH ELFTA AT LL VVL G T A QLF D YA GLS AG LG G FL 238
Cdd:TIGR00932 157 LL AT - SA S TEHVAL AL LLLK V F LA FLL L V LL grwllrpvl RLT A ELRPS ELFTA GS LL LMF G S A YFA D LL GLS MA LG A FL 235
250 260 270
....*....|....*....|....*....|....*...
gi 1551827355 239 V G ML L A ES RH R NE LE HTI EP FK G L LL G LFF LA VGMSV N 276
Cdd:TIGR00932 236 A G VV L S ES EY R HK LE SDL EP IG G V LL P LFF IS VGMSV D 273
Na_H_Exchanger
pfam00999 Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH ...
4-369
2.82e-38
Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.
Pssm-ID: 425982 [Multi-domain]
Cd Length: 377
Bit Score: 141.62
E-value: 2.82e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 4 LTI L LIA A V L CVP LA Q RL G L GA I P G YLL AG GVI GPSGLGL VTD V PDIMR V - S EW G VVMM LF VI GLEL APKR L WAMRREVF 82
Cdd:pfam00999 1 IVL L ILL A L L APL LA R RL K L PP I V G LII AG ILL GPSGLGL ISE V DEDLE V l S NL G LPPL LF LA GLEL DLRE L RKNGGSIL 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 83 GAGT L QMVVCGA L L G AVFGAGL rhl A G MGWQA A I L C G LS L ALS S TA V A L RL L E E R G L V RTP LG RSA LG VLL L Q D MA A IPM 162
Cdd:pfam00999 81 LLAL L GVLIPFV L I G LLLYLLG --- L G IPLLE A L L F G AI L SAT S PV V V L AI L K E L G R V PER LG TLL LG ESV L N D GV A VVL 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 163 L - V AAG L LGSD G DSAPSFEAA L VAV VV VLACYR L R LL DW ------- AARSQLH EL FTAAT LL VV L GT A Q L FDYA G L S AG L 234
Cdd:pfam00999 158 L a V LLA L AQGV G GGSDLGWLL L IFL VV AVGGLL L G LL IG wllrlit RFTDDDR EL EVLLV LL LA L LA A L L AEAL G V S GI L 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 235 G G FL V G ML L A E SRHR N E L EHTI EPF KGL L LGLF F - LA VG M S VNVEE - A L DY W PY VL AGV VA L L SLKA L VLYGIA RL M GL P 312
Cdd:pfam00999 238 G A FL A G LV L S E YPFA N K L SEKL EPF GYG L FNPL F f VL VG L S LDLSS l L L SV W IL VL LAL VA I L LGRF L GVFLLL RL L GL S 317
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1551827355 313 HYHR L LYALVLA Q G G EF S FVIFNEAWDNHLMSL E QRD LL AI VV AISMGAVP I VIRL L 369
Cdd:pfam00999 318 LREA L IIGFGGL Q R G AV S LALAAIGPLLGIIAR E LYP LL IV VV LFTVLVQG I TLKP L 374
Name
Accession
Description
Interval
E-value
PRK03562
PRK03562 glutathione-regulated potassium-efflux system protein KefC; Provisional
6-372
1.82e-111
glutathione-regulated potassium-efflux system protein KefC; Provisional
Pssm-ID: 235131 [Multi-domain]
Cd Length: 621
Bit Score: 339.66
E-value: 1.82e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 6 I L L I AAVL C VP L A Q RLGLG AIP GYL L AG GV IGP S GL G LVTDV PD I MRVS E W GVV M MLFVIGLEL A P K RLW AM RR EV FG A G 85
Cdd:PRK03562 12 I Y L G AAVL I VP I A V RLGLG SVL GYL I AG CI IGP W GL R LVTDV ES I LHFA E F GVV L MLFVIGLEL D P Q RLW KL RR SI FG G G 91
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 86 T LQMV V CG A LLG AVFGA glrhl A G MG WQ A A I L C GL S LALSSTA V A LRLLE ER G L VR T PL GRSA LGV LL L QD M AAIP MLVA 165
Cdd:PRK03562 92 A LQMV A CG G LLG LFCML ----- L G LR WQ V A L L I GL G LALSSTA I A MQAMN ER N L MV T QM GRSA FAI LL F QD I AAIP LVAM 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 166 AG LL GSD G D S APSFEA AL V A VV V VL A C -------- Y RL R - L L DWA ARS Q L H E L FTA AT L LV V L G TAQ L FDYA GLS AG LG G 236
Cdd:PRK03562 167 IP LL AAS G A S TTLGAF AL S A LK V AG A L alvvlggr Y VT R p A L RFV ARS G L R E V FTA VA L FL V F G FGL L MEEV GLS MA LG A 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 237 FL V G M LLA E S RH R NE LE HT IEPFKGLLLGLFF L AVGMS VNVEEA L DYWPYV L AGVVAL L SL K ALV L YGI AR LM G L P HYH R 316
Cdd:PRK03562 247 FL A G V LLA S S EY R HA LE SD IEPFKGLLLGLFF I AVGMS IDFGTL L ENPLRI L ILLLGF L AI K IAM L WLL AR PL G V P RKQ R 326
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1551827355 317 LLY A LV L A QGGEF S FV I F NE A WDNHLMSL E QRD LL AIV VA I SM G A V P IVIR LL E RL 372
Cdd:PRK03562 327 RWF A VL L G QGGEF A FV V F GA A QMANVLEP E WAK LL TLA VA L SM A A T P LLLV LL D RL 382
PRK03659
PRK03659 glutathione-regulated potassium-efflux system protein KefB; Provisional
5-386
1.21e-109
glutathione-regulated potassium-efflux system protein KefB; Provisional
Pssm-ID: 179625 [Multi-domain]
Cd Length: 601
Bit Score: 334.30
E-value: 1.21e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 5 TIL L I AAV LC VPLAQRLG L GA IP GYLLAG GV IGP S GLG LVT DV PD I MRV SE W GVV MML F V IGLEL A P KR LW AM RR EV FG A 84
Cdd:PRK03659 11 VLF L F AAV VA VPLAQRLG I GA VL GYLLAG IA IGP W GLG FIS DV DE I LHF SE L GVV FLM F I IGLEL N P SK LW QL RR SI FG V 90
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 85 G TL Q MVVCG A L L G avfga GL RH L AGMG WQAA ILC G LS LA L SSTA V AL R L LE E R G LV R TPL G RSALG VLL L QD M A A IP M L V 164
Cdd:PRK03659 91 G AA Q VLLSA A V L A ----- GL LM L TDFS WQAA VVG G IG LA M SSTA M AL Q L MR E K G MN R SES G QLGFS VLL F QD L A V IP A L A 165
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 165 AAG LL GSDG D SAPSFEAALVA V VVVLAC ----- Y R LR - L LDWA A R S QLH E L FTAA T LL V VLG T A QLF D YA GLS AG LG G F L 238
Cdd:PRK03659 166 LVP LL AGSA D EHFDWMKIGMK V LAFAGM liggr Y L LR p L FRFI A A S GVR E V FTAA A LL L VLG S A LFM D AL GLS MA LG T F I 245
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 239 V G M LLAES RH R N ELE HT IEPFKGLLLGLFF LA VGM SV N VEEALDYWPY VL AG VV A L LSL K A LVLY GI ARL M GL PHYH R LL 318
Cdd:PRK03659 246 A G V LLAES EY R H ELE IA IEPFKGLLLGLFF IS VGM AL N LGVLYTHLLW VL IS VV V L VAV K G LVLY LL ARL Y GL RSSE R MQ 325
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1551827355 319 Y A L VL A QGGEF S FV I F NE A WDNH L MSLE Q RD LL AI VV AI SM GAV P IVIR L LER - L PG R YG G IGDMAVT P 386
Cdd:PRK03659 326 F A G VL S QGGEF A FV L F SA A SSQR L LQGD Q MA LL LV VV TL SM MTT P LLMK L IDK w L AR R LN G PEEEDEK P 394
KefB
COG0475 Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism]; ...
4-375
7.86e-81
Kef-type K+ transport system, membrane component KefB [Inorganic ion transport and metabolism];
Pssm-ID: 440243 [Multi-domain]
Cd Length: 384
Bit Score: 253.15
E-value: 7.86e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 4 L TI LL I AAVL CVP LA Q RLGL GAIP GY L LAG GVI GPSGLGL VT D VPDIMRVS E W GVV MM LF V IGLEL AP KRL WA M R R EVF G 83
Cdd:COG0475 9 L GL LL L AAVL AGL LA R RLGL PSVL GY I LAG ILL GPSGLGL IE D SEALELLA E L GVV LL LF L IGLEL DL KRL RK M G R RAL G 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 84 A G T LQ MVVCGA L LGAVF gaglr H L A G MGWQ AA ILC G LS LA LS STA VA L RL L E E R GL VR TPLG RSA LGV L L LQ D M AAI PM L 163
Cdd:COG0475 89 I G L LQ VLLPFL L GFLLA ----- L L L G LSLA AA LFL G AA LA AT STA IV L KV L K E L GL LK TPLG QLI LGV A L FD D I AAI LL L 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 164 - VAAG L L G SDGDSAPSFE A A L V A VVVVLACYRL ------ RL LDWA AR SQLH ELF TAAT LL V VL GT A Q L FDYA GLSA G LG G 236
Cdd:COG0475 164 a LVPA L A G GGSVAGSLLL A L L K A LLFLALLLLV gryllr RL FRLV AR TRSR ELF LLFA LL L VL LA A A L AELL GLSA A LG A 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 237 FL V G ML LAES RH R N ELE HT IEPF KG L L L G LFF LA VG M S VNVEEA L DYWPYV L AG V V A LLSL K A L VL Y GI ARL M GL PHYHR 316
Cdd:COG0475 244 FL A G LV LAES EY R H ELE EK IEPF GD L F L P LFF VS VG L S LDLSAL L SNPLLA L LL V L A AIVG K L L GA Y LA ARL F GL SRREA 323
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 1551827355 317 L LYA L V LA QG GEF SF V IFNEAWDNH L M S L E QRDL L AI VV AISMGAV P IVI RL LE RL PG R 375
Cdd:COG0475 324 L RIG L L LA PR GEF AL V LASLGLSAG L I S P E LFAA L VL VV LLTTLLT P LLL RL AL RL AE R 382
RosB
COG4651 Predicted Kef-type K+ transport protein, K+/H+ antiporter domain [Inorganic ion transport and ...
4-375
1.43e-68
Predicted Kef-type K+ transport protein, K+/H+ antiporter domain [Inorganic ion transport and metabolism];
Pssm-ID: 443689 [Multi-domain]
Cd Length: 564
Bit Score: 226.78
E-value: 1.43e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 4 LTIL L IA A VLCVP LAQRL GLGA I P GYLLAG GV IGP SGL GLV T DV PD I MRVS E W GV VMM LF VI GLE LAP K R L W A M R REVFG 83
Cdd:COG4651 10 IALI L GL A AVLGL LAQRL RQPP I V GYLLAG VL IGP FTP GLV A DV EL I EQLA E I GV ILL LF GV GLE FSL K D L L A V R KIALP 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 84 AGT LQ MV vcgal L GAVF G A G LRH L A G MGWQAAILC GL S L A LSST A V A L R LLE E RG LVR T PL GR S A L G V L LL QD M A AIP ML 163
Cdd:COG4651 90 GAL LQ IA ----- L TTLL G F G IAL L L G WSLGESLVF GL A L S LSST V V L L K LLE D RG ELD T LH GR I A V G W L IV QD L A VVL ML 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 164 V AAGL L GSD G DSAPS ------ FEA AL VAVVVVLACY R L -- R LL DWA AR SQLH ELF TA A T L LVV LG T A Q L FDYA GLS AG LG 235
Cdd:COG4651 165 V LLPA L AGG G GGLLG tlgltl LKV AL FVALMLVVGR R V ip W LL HRV AR TRSR ELF LL A V L AIC LG V A Y L AALF GLS FA LG 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 236 G FL V GM L LAES RHRNELEHTIE P FKGLLLG LFF LA VGM SVNVEEA L DYWPY VLA GVVAL L SL K A L VLYG I ARLM G L P HYH 315
Cdd:COG4651 245 A FL A GM V LAES EYSHQAAAELL P LRDAFAV LFF VS VGM LFDPSFL L ENPLP VLA LLLIV L IG K P L IAFL I VLAL G Y P LRT 324
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 316 R LL YA L V LAQ G GEFSF VIFNEAWDNH L M S L E QRD L LAI V VAISMGAV P IV I R L LER L PG R 375
Cdd:COG4651 325 A LL VG L S LAQ I GEFSF ILAALGLSLG L L S E E AYQ L ILA V AILTIALS P YL I A L ADP L YA R 384
2a37
TIGR00932 transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding ...
8-276
6.59e-59
transporter, monovalent cation:proton antiporter-2 (CPA2) family; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273348 [Multi-domain]
Cd Length: 273
Bit Score: 193.25
E-value: 6.59e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 8 L I AAVL C VPL AQ RLG LGAIP GYLLAG GV IGPSGLGL VTD V PDIMRVS E W GV VMML F V IGLEL APK RLW AM R REV FG A G T L 87
Cdd:TIGR00932 1 L L AAVL A VPL SR RLG IPSVL GYLLAG VL IGPSGLGL ISN V EGVNHLA E F GV ILLM F L IGLEL DLE RLW KL R KAA FG V G V L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 88 Q MV V C G A LL gavf G AG L R HL A G MGWQ AA ILC G LS LALSSTAV ALRL L E ERGL VR TP L G RSA LG V LL L QD M A AI P M L VAAG 167
Cdd:TIGR00932 81 Q VL V P G V LL ---- G LL L G HL L G LALG AA VVI G II LALSSTAV VVQV L K ERGL LK TP F G QTV LG I LL F QD I A VV P L L ALLP 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 168 LL GS d GD S APSFEA AL VAVV V V LA CYR L R LL --------- DWA A RSQLH ELFTA AT LL VVL G T A QLF D YA GLS AG LG G FL 238
Cdd:TIGR00932 157 LL AT - SA S TEHVAL AL LLLK V F LA FLL L V LL grwllrpvl RLT A ELRPS ELFTA GS LL LMF G S A YFA D LL GLS MA LG A FL 235
250 260 270
....*....|....*....|....*....|....*...
gi 1551827355 239 V G ML L A ES RH R NE LE HTI EP FK G L LL G LFF LA VGMSV N 276
Cdd:TIGR00932 236 A G VV L S ES EY R HK LE SDL EP IG G V LL P LFF IS VGMSV D 273
Na_H_Exchanger
pfam00999 Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH ...
4-369
2.82e-38
Sodium/hydrogen exchanger family; Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. These antiporters contain 10-12 transmembrane regions (M) at the amino-terminus and a large cytoplasmic region at the carboxyl terminus. The transmembrane regions M3-M12 share identity with other members of the family. The M6 and M7 regions are highly conserved. Thus, this is thought to be the region that is involved in the transport of sodium and hydrogen ions. The cytoplasmic region has little similarity throughout the family.
Pssm-ID: 425982 [Multi-domain]
Cd Length: 377
Bit Score: 141.62
E-value: 2.82e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 4 LTI L LIA A V L CVP LA Q RL G L GA I P G YLL AG GVI GPSGLGL VTD V PDIMR V - S EW G VVMM LF VI GLEL APKR L WAMRREVF 82
Cdd:pfam00999 1 IVL L ILL A L L APL LA R RL K L PP I V G LII AG ILL GPSGLGL ISE V DEDLE V l S NL G LPPL LF LA GLEL DLRE L RKNGGSIL 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 83 GAGT L QMVVCGA L L G AVFGAGL rhl A G MGWQA A I L C G LS L ALS S TA V A L RL L E E R G L V RTP LG RSA LG VLL L Q D MA A IPM 162
Cdd:pfam00999 81 LLAL L GVLIPFV L I G LLLYLLG --- L G IPLLE A L L F G AI L SAT S PV V V L AI L K E L G R V PER LG TLL LG ESV L N D GV A VVL 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 163 L - V AAG L LGSD G DSAPSFEAA L VAV VV VLACYR L R LL DW ------- AARSQLH EL FTAAT LL VV L GT A Q L FDYA G L S AG L 234
Cdd:pfam00999 158 L a V LLA L AQGV G GGSDLGWLL L IFL VV AVGGLL L G LL IG wllrlit RFTDDDR EL EVLLV LL LA L LA A L L AEAL G V S GI L 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 235 G G FL V G ML L A E SRHR N E L EHTI EPF KGL L LGLF F - LA VG M S VNVEE - A L DY W PY VL AGV VA L L SLKA L VLYGIA RL M GL P 312
Cdd:pfam00999 238 G A FL A G LV L S E YPFA N K L SEKL EPF GYG L FNPL F f VL VG L S LDLSS l L L SV W IL VL LAL VA I L LGRF L GVFLLL RL L GL S 317
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1551827355 313 HYHR L LYALVLA Q G G EF S FVIFNEAWDNHLMSL E QRD LL AI VV AISMGAVP I VIRL L 369
Cdd:pfam00999 318 LREA L IIGFGGL Q R G AV S LALAAIGPLLGIIAR E LYP LL IV VV LFTVLVQG I TLKP L 374
PRK10669
PRK10669 putative cation:proton antiport protein; Provisional
8-371
8.43e-27
putative cation:proton antiport protein; Provisional
Pssm-ID: 182633 [Multi-domain]
Cd Length: 558
Bit Score: 112.11
E-value: 8.43e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 8 L IA A VLCVP LA Q RL GLGAIP GYLLAG GVI GP SGL G L V T D VPDIMRVS E W GV VMML F VI GL ELAP K R L W A MRREVFGAGTL 87
Cdd:PRK10669 15 L VL A FILGM LA N RL RISPLV GYLLAG VLA GP FTP G F V A D TKLAPELA E L GV ILLM F GV GL HFSL K D L M A VKSIAIPGAIA 94
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 88 Q MV V CGA L lgavf G AG L RHLA G MGWQAA I LC GL S L ALS ST A V A LR L LEER G L VRTPL G RS A L G V L LLQ D MAAIPM LV --- 164
Cdd:PRK10669 95 Q IA V ATL L ----- G MA L SAVL G WSLMTG I VF GL C L STA ST V V L LR A LEER Q L IDSQR G QI A I G W L IVE D LVMVLT LV llp 169
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 165 - A AG LLGSDGDSAPSFEAA L VAVVVVLACYRL ------- RL LD W ---- A A RSQLH ELFT AAT L LVV LG T A ---- Q LFD ya 228
Cdd:PRK10669 170 a V AG MMEQGDVGFATLAVD L GITIGKVIAFIA immlvgr RL VP W ilar S A ATGSR ELFT LSV L ALA LG I A fgav E LFD -- 247
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 229 g L S AG LG G F LV GM L L A ES RHRNELE H TIE P FKGLLLG LFF LA VGM SVNVEEALDYWPY VLA GVVALLSL K A L VLYGIA RL 308
Cdd:PRK10669 248 - V S FA LG A F FA GM V L N ES ELSHRAA H DTL P LRDAFAV LFF VS VGM LFDPMILIQQPLA VLA TLAIIVFG K S L AAFFLV RL 326
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1551827355 309 M G LPHYHR L LY A LV LAQ G GEF S F VIFNEAWDNH L MSLEQRD L LAIVVAI S MGAV P IVIR LLER 371
Cdd:PRK10669 327 F G HSRRTA L TI A AS LAQ I GEF A F ILAGLGMALN L LPQAGQN L VLAGAIL S IMLN P VLFT LLER 389
NhaP
COG0025 NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion transport and metabolism];
1-139
4.73e-08
NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion transport and metabolism];
Pssm-ID: 439796 [Multi-domain]
Cd Length: 506
Bit Score: 54.97
E-value: 4.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 1 ME L LTI LL IAAV L CVP LA Q RL G L G A IPGY LLAG GVI GP - S GL G L VTDVP D IMRVS E WGVVMM LF VIG L E L APKR L WAMR R 79
Cdd:COG0025 4 LL L ILL LL LLGL L SQW LA R RL K L P A PLLL LLAG ILL GP g L GL E L DPELG D LEPLL E LFLPPL LF EAA L N L DLRE L RRNG R 83
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 80 EVFGAGTLQMVVCGALLGAV fgag LRH L A G MGWQ AA I L C G LS LA LSSTAVALRL L EER G L 139
Cdd:COG0025 84 PILRLAVVGVLLTTLAVALA ---- AHW L L G LPLA AA L L L G AI LA PTDPVAVSPI L RRL G V 139
PLN03159
PLN03159 cation/H(+) antiporter 15; Provisional
30-166
1.41e-04
cation/H(+) antiporter 15; Provisional
Pssm-ID: 215608 [Multi-domain]
Cd Length: 832
Bit Score: 44.11
E-value: 1.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1551827355 30 L L A G GVI GPS G LG LVT ---------- D V PDIMRVSEW G VVMM LF VI G L E L apk RLWAM RR E vf G AGT L QMVVC G AL L --- 96
Cdd:PLN03159 74 I L G G VIL GPS V LG QSE vfantifplr S V MVLETMANL G LLYF LF LV G V E M --- DISVI RR T -- G KKA L AIAIA G MA L pfc 148
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1551827355 97 - G AV F GAGLRHLAGMGW Q AAILCG L SL ALS S TA -- V AL R L L E E RG L VR T P LGR S A LGVL L LQ DM A A IPM L VA A 166
Cdd:PLN03159 149 i G LA F SFIFHQVSRNVH Q GTFILF L GV ALS V TA fp V LA R I L A E IK L IN T E LGR I A MSAA L VN DM C A WIL L AL A 221
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
