NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|226734409|sp|B7JKD0|]
View 

RecName: Full=Large ribosomal subunit protein uL24; AltName: Full=50S ribosomal protein L24

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 1-101 3.09e-55

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


:

Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 166.39  E-value: 3.09e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226734409   1 MHVKKGDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLNPQGGIITKEAPIHVSNVMILDPKTGEPTR 80
Cdd:COG0198    3 MKIKKGDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNPQGGIIEKEAPIHISNVMLVDPKTGKPTR 82

                         90       100
                 ....*....|....*....|..
gi 226734409  81 VGFKV-EDGKKVRIAKKSGELL 101
Cdd:COG0198   83 VGFKVlEDGKKVRVCKKSGEVI 104
 
Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 1-101 3.09e-55

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 166.39  E-value: 3.09e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226734409   1 MHVKKGDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLNPQGGIITKEAPIHVSNVMILDPKTGEPTR 80
Cdd:COG0198    3 MKIKKGDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNPQGGIIEKEAPIHISNVMLVDPKTGKPTR 82

                         90       100
                 ....*....|....*....|..
gi 226734409  81 VGFKV-EDGKKVRIAKKSGELL 101
Cdd:COG0198   83 VGFKVlEDGKKVRVCKKSGEVI 104
rplX_bact TIGR01079
ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar ...
 1-101 1.06e-41

ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar forms of ribosomal protein L24. It excludes eukaryotic and archaeal forms, designated L26 in eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273431 [Multi-domain]  Cd Length: 102  Bit Score: 132.39  E-value: 1.06e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226734409    1 MHVKKGDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLNPQGGIITKEAPIHVSNVMILDPKTGEPTR 80
Cdd:TIGR01079   1 MKIKKGDTVKVISGKDKGKRGKVLKVLPKKNKVIVEGVNMVKKHVKPVPANRQGGIIEKEAPIHISNVMLFDPKTGKATR 80

                          90       100
                  ....*....|....*....|..
gi 226734409   81 VGFKV-EDGKKVRIAKKSGELL 101
Cdd:TIGR01079  81 VGYRFeEDGKKVRVFKKNGEII 102
ribosomal_L24 pfam17136
Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ...
 38-98 5.66e-30

Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ribosomal subunit proteins L24. It also carries some mitochondrial 39S L24 proteins.


Pssm-ID: 465359  Cd Length: 60  Bit Score: 101.37  E-value: 5.66e-30
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 226734409   38 VNIVKKHSKPSQLNPQGGIITKEAPIHVSNVMILDPKTGEPTRVGFKvEDGKKVRIAKKSG 98
Cdd:pfam17136   1 VNMVKKHVKPSQQNPQGGIIEKEAPIHVSNVMLVDPKCGKPTRVGFK-EDGKKVRVSKKTG 60
KOW_RPL26 cd06089
KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at ...
 6-70 3.06e-27

KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at their N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. RPL26 makes a very minor contributions to the biogenesis, structure, and function of 60s ribosomal subunits. However, RPL24 is essential to generate the first intermediate during 50s ribosomal subunits assembly. RPL26 have an extra-ribosomal function to enhances p53 translation after DNA damage.


Pssm-ID: 240513  Cd Length: 65  Bit Score: 94.50  E-value: 3.06e-27
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 226734409   6 GDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLNPQGGIITKEAPIHVSNVMI 70
Cdd:cd06089    1 GDEVQVIRGKDKGKQGKVLKVDRKKNRVIVEGVNVVKKHVKPSQENPQGGIIEVEAPIHISNVML 65
rplX PRK12281
50S ribosomal protein L24; Reviewed
 1-68 2.86e-26

50S ribosomal protein L24; Reviewed


Pssm-ID: 183399  Cd Length: 76  Bit Score: 92.41  E-value: 2.86e-26
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 226734409   1 MHVKKGDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLNPQGGIITKEAPIHVSNV 68
Cdd:PRK12281   5 LKVKKGDMVKVIAGDDKGKTGKVLAVLPKKNRVIVEGVKIAKKAIKPSQKNPNGGFIEKEMPIHISNV 72
 
Name Accession Description Interval E-value
RplX COG0198
Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 ...
 1-101 3.09e-55

Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L24 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439968 [Multi-domain]  Cd Length: 104  Bit Score: 166.39  E-value: 3.09e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226734409   1 MHVKKGDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLNPQGGIITKEAPIHVSNVMILDPKTGEPTR 80
Cdd:COG0198    3 MKIKKGDTVIVIAGKDKGKRGKVLKVLPKKNRVIVEGVNIVKKHQKPNQQNPQGGIIEKEAPIHISNVMLVDPKTGKPTR 82

                         90       100
                 ....*....|....*....|..
gi 226734409  81 VGFKV-EDGKKVRIAKKSGELL 101
Cdd:COG0198   83 VGFKVlEDGKKVRVCKKSGEVI 104
rplX_bact TIGR01079
ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar ...
 1-101 1.06e-41

ribosomal protein L24, bacterial/organelle; This model recognizes bacterial and organellar forms of ribosomal protein L24. It excludes eukaryotic and archaeal forms, designated L26 in eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273431 [Multi-domain]  Cd Length: 102  Bit Score: 132.39  E-value: 1.06e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226734409    1 MHVKKGDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLNPQGGIITKEAPIHVSNVMILDPKTGEPTR 80
Cdd:TIGR01079   1 MKIKKGDTVKVISGKDKGKRGKVLKVLPKKNKVIVEGVNMVKKHVKPVPANRQGGIIEKEAPIHISNVMLFDPKTGKATR 80

                          90       100
                  ....*....|....*....|..
gi 226734409   81 VGFKV-EDGKKVRIAKKSGELL 101
Cdd:TIGR01079  81 VGYRFeEDGKKVRVFKKNGEII 102
ribosomal_L24 pfam17136
Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ...
 38-98 5.66e-30

Ribosomal proteins 50S L24/mitochondrial 39S L24; This is the family of bacterial 50S ribosomal subunit proteins L24. It also carries some mitochondrial 39S L24 proteins.


Pssm-ID: 465359  Cd Length: 60  Bit Score: 101.37  E-value: 5.66e-30
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 226734409   38 VNIVKKHSKPSQLNPQGGIITKEAPIHVSNVMILDPKTGEPTRVGFKvEDGKKVRIAKKSG 98
Cdd:pfam17136   1 VNMVKKHVKPSQQNPQGGIIEKEAPIHVSNVMLVDPKCGKPTRVGFK-EDGKKVRVSKKTG 60
KOW_RPL26 cd06089
KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at ...
 6-70 3.06e-27

KOW motif of Ribosomal Protein L26; RPL26 and its bacterial paralogs RPL24 have a KOW motif at their N terminal. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. RPL26 makes a very minor contributions to the biogenesis, structure, and function of 60s ribosomal subunits. However, RPL24 is essential to generate the first intermediate during 50s ribosomal subunits assembly. RPL26 have an extra-ribosomal function to enhances p53 translation after DNA damage.


Pssm-ID: 240513  Cd Length: 65  Bit Score: 94.50  E-value: 3.06e-27
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 226734409   6 GDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLNPQGGIITKEAPIHVSNVMI 70
Cdd:cd06089    1 GDEVQVIRGKDKGKQGKVLKVDRKKNRVIVEGVNVVKKHVKPSQENPQGGIIEVEAPIHISNVML 65
rplX PRK12281
50S ribosomal protein L24; Reviewed
 1-68 2.86e-26

50S ribosomal protein L24; Reviewed


Pssm-ID: 183399  Cd Length: 76  Bit Score: 92.41  E-value: 2.86e-26
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 226734409   1 MHVKKGDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLNPQGGIITKEAPIHVSNV 68
Cdd:PRK12281   5 LKVKKGDMVKVIAGDDKGKTGKVLAVLPKKNRVIVEGVKIAKKAIKPSQKNPNGGFIEKEMPIHISNV 72
rpl24 CHL00141
ribosomal protein L24; Validated
 1-74 2.44e-20

ribosomal protein L24; Validated


Pssm-ID: 214374  Cd Length: 83  Bit Score: 77.76  E-value: 2.44e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 226734409   1 MHVKKGDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLNPQGGIITKEAPIHVSNVMILDPK 74
Cdd:CHL00141   7 MHVKIGDTVKIISGSDKGKIGEVLKIIKKSNKVIVKGINIKFKHIKPNKENEVGEIKQFEAPIHSSNVMLYNEE 80
Ribosomal_L26 pfam16906
Ribosomal proteins L26 eukaryotic, L24P archaeal; Ribosomal_L26 is a family of the 50S and the ...
 1-70 1.96e-06

Ribosomal proteins L26 eukaryotic, L24P archaeal; Ribosomal_L26 is a family of the 50S and the 60S ribosomal proteins from eukaryotes - L26 - and archaea - L25.


Pssm-ID: 465307 [Multi-domain]  Cd Length: 114  Bit Score: 42.88  E-value: 1.96e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226734409    1 MHVKKGDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLnpqggiitkeaPIHVSNVMI 70
Cdd:pfam16906  40 LPIRKGDEVKVVRGDFKGREGKVVQVYRKKYRIHVEGVTREKANGTTVPV-----------PIHPSKVVI 98
rplX_A_E TIGR01080
ribosomal protein uL24, archaeal/eukaryotic form; This model represents the archaeal and ...
 1-72 3.45e-06

ribosomal protein uL24, archaeal/eukaryotic form; This model represents the archaeal and eukaryotic branch of the ribosomal protein L24p/L26e family. Bacterial and organellar forms are represented by related model TIGR01079. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273432  Cd Length: 114  Bit Score: 42.14  E-value: 3.45e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 226734409    1 MHVKKGDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKpsqlnpqggiiTKEAPIHVSNVMILD 72
Cdd:TIGR01080  40 LPIRKGDEVRIVRGDFKGHEGKVSKVDRKRYRIYVEGVTKEKVDGT-----------EVPVPLHPSNVMITK 100
PTZ00194 PTZ00194
60S ribosomal protein L26; Provisional
 1-74 4.00e-04

60S ribosomal protein L26; Provisional


Pssm-ID: 185508  Cd Length: 143  Bit Score: 37.04  E-value: 4.00e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 226734409   1 MHVKKGDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLnpqggiitkeaPIHVSNVMILDPK 74
Cdd:PTZ00194  45 MPVRKDDEVMVVRGHHKGREGKVTAVYRKKWVIHIEKITREKANGEPVQI-----------GIHPSNVIITKLK 107
KOW pfam00467
KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, ...
 5-36 8.11e-04

KOW motif; This family has been extended to coincide with ref. The KOW (Kyprides, Ouzounis, Woese) motif is found in a variety of ribosomal proteins and NusG.


Pssm-ID: 425698 [Multi-domain]  Cd Length: 32  Bit Score: 34.28  E-value: 8.11e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 226734409    5 KGDKVQVITGKDKGKQGVILVAFPKQNRVIVE 36
Cdd:pfam00467   1 KGDVVRVIAGPFKGKVGKVVEVDDKKNRVLVE 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH