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Conserved domains on  [gi|2826142|dbj|BAA24539|]
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myocyte enhancer factor 2B type B-1 [Mus musculus]

Protein Classification

MEF2 family transcription factor( domain architecture ID 13416711)

MEF2 family transcription factor is a MADS (MCM1, Agamous, Deficiens, and SRF)-box transcription factor, similar to human myocyte-specific enhancer factor 2C, a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MADS_MEF2_like cd00265
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ...
 2-78 3.90e-37

MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


:

Pssm-ID: 238165 [Multi-domain]  Cd Length: 77  Bit Score: 128.05  E-value: 3.90e-37
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2826142    2 GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHES 78
Cdd:cd00265   1 GRGKIEIKRIENSTNRQVTFSKRRNGLLKKAHELSVLCDAEVALIIFSSSGKLYEFSSPSMEKIIERYQKTSGSSLW 77
ARG80 super family cl34888
Regulator of arginine metabolism and related MADS box-containing transcription factors ...
 1-206 5.82e-10

Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription];


The actual alignment was detected with superfamily member COG5068:

Pssm-ID: 227400 [Multi-domain]  Cd Length: 412  Bit Score: 60.03  E-value: 5.82e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVL------LKYTEYSE 74
Cdd:COG5068  81 VTGRKIGISYITNKTKRSVTFSKRKHGINKKAFELSVLTGTEVLLLVISENGLVHTFTTPKLESVVkslegkSLIQSPCS 160

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142   75 PHESRTNADILQTLKRRGVGLDGPELDMEEGPEGPGEKLLRTLGGDRGSASPRPRiYPVAPAMSVSELSYRVPPATPgcd 154
Cdd:COG5068 161 NAPSDSSEEPSSSASFSVDPNDNNPMGSFQHNGSPQTNFIPLQNPQTQQYQQHSS-RKDHPTVPHSNTNNGRPPAKF--- 236

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|...
gi 2826142  155 pgglgEVPSVHSRPAYFR-PPGLGHPIFSPSHLASKTPPPLYLATDGRRPDLP 206
Cdd:COG5068 237 -----MIPELHSSHSTLDlPSDFISDSGFPNQSSTSIFPLDSAIIQITPPHLP 284
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 124-339 1.55e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 1.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    124 ASPRPRIYPVAPAMSVSELSYRVPPATPGCDPGGLGEVPSVHSRPAYFRPPGLGHPIFSPSHLASKTPPPLYLATDGRRP 203
Cdd:PHA03247 2737 AAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAA 2816

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    204 DLPPGLVGARGGLGTSRSLysglqsPGAPGPALGSFA-FLPSGSTDCSPGDAAQGPlqPSPWPPTRDAVdPARPVARSLC 282
Cdd:PHA03247 2817 ALPPAASPAGPLPPPTSAQ------PTAPPPPPGPPPpSLPLGGSVAPGGDVRRRP--PSRSPAAKPAA-PARPPVRRLA 2887

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2826142    283 KEGPPSRGASPPTPPVSIKSERlSPVTGTSGDFPRSFPYPLLLARPLAEPLRPSASL 339
Cdd:PHA03247 2888 RPAVSRSTESFALPPDQPERPP-QPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPL 2943
 
Name Accession Description Interval E-value
MADS_MEF2_like cd00265
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ...
 2-78 3.90e-37

MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238165 [Multi-domain]  Cd Length: 77  Bit Score: 128.05  E-value: 3.90e-37
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2826142    2 GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHES 78
Cdd:cd00265   1 GRGKIEIKRIENSTNRQVTFSKRRNGLLKKAHELSVLCDAEVALIIFSSSGKLYEFSSPSMEKIIERYQKTSGSSLW 77
MADS smart00432
MADS domain;
2-60 3.46e-30

MADS domain;


Pssm-ID: 197721 [Multi-domain]  Cd Length: 59  Bit Score: 109.57  E-value: 3.46e-30
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2826142       2 GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASS 60
Cdd:smart00432   1 GRRKIEIKRIENKTNRQVTFSKRRNGLFKKAHELSVLCDAEVALIVFSPTGKLYEFASP 59
SRF-TF pfam00319
SRF-type transcription factor (DNA-binding and dimerization domain);
10-57 3.69e-23

SRF-type transcription factor (DNA-binding and dimerization domain);


Pssm-ID: 459760 [Multi-domain]  Cd Length: 48  Bit Score: 90.56  E-value: 3.69e-23
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2826142     10 RILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQY 57
Cdd:pfam00319   1 RIENKRARQVTFSKRRKGLFKKASELSVLCGAEVAVIVFSPTGKLYTF 48
ARG80 COG5068
Regulator of arginine metabolism and related MADS box-containing transcription factors ...
 1-206 5.82e-10

Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription];


Pssm-ID: 227400 [Multi-domain]  Cd Length: 412  Bit Score: 60.03  E-value: 5.82e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVL------LKYTEYSE 74
Cdd:COG5068  81 VTGRKIGISYITNKTKRSVTFSKRKHGINKKAFELSVLTGTEVLLLVISENGLVHTFTTPKLESVVkslegkSLIQSPCS 160

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142   75 PHESRTNADILQTLKRRGVGLDGPELDMEEGPEGPGEKLLRTLGGDRGSASPRPRiYPVAPAMSVSELSYRVPPATPgcd 154
Cdd:COG5068 161 NAPSDSSEEPSSSASFSVDPNDNNPMGSFQHNGSPQTNFIPLQNPQTQQYQQHSS-RKDHPTVPHSNTNNGRPPAKF--- 236

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|...
gi 2826142  155 pgglgEVPSVHSRPAYFR-PPGLGHPIFSPSHLASKTPPPLYLATDGRRPDLP 206
Cdd:COG5068 237 -----MIPELHSSHSTLDlPSDFISDSGFPNQSSTSIFPLDSAIIQITPPHLP 284
PHA03247 PHA03247
large tegument protein UL36; Provisional
 124-339 1.55e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 1.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    124 ASPRPRIYPVAPAMSVSELSYRVPPATPGCDPGGLGEVPSVHSRPAYFRPPGLGHPIFSPSHLASKTPPPLYLATDGRRP 203
Cdd:PHA03247 2737 AAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAA 2816

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    204 DLPPGLVGARGGLGTSRSLysglqsPGAPGPALGSFA-FLPSGSTDCSPGDAAQGPlqPSPWPPTRDAVdPARPVARSLC 282
Cdd:PHA03247 2817 ALPPAASPAGPLPPPTSAQ------PTAPPPPPGPPPpSLPLGGSVAPGGDVRRRP--PSRSPAAKPAA-PARPPVRRLA 2887

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2826142    283 KEGPPSRGASPPTPPVSIKSERlSPVTGTSGDFPRSFPYPLLLARPLAEPLRPSASL 339
Cdd:PHA03247 2888 RPAVSRSTESFALPPDQPERPP-QPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPL 2943
 
Name Accession Description Interval E-value
MADS_MEF2_like cd00265
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ...
 2-78 3.90e-37

MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238165 [Multi-domain]  Cd Length: 77  Bit Score: 128.05  E-value: 3.90e-37
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2826142    2 GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHES 78
Cdd:cd00265   1 GRGKIEIKRIENSTNRQVTFSKRRNGLLKKAHELSVLCDAEVALIIFSSSGKLYEFSSPSMEKIIERYQKTSGSSLW 77
MADS smart00432
MADS domain;
2-60 3.46e-30

MADS domain;


Pssm-ID: 197721 [Multi-domain]  Cd Length: 59  Bit Score: 109.57  E-value: 3.46e-30
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2826142       2 GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASS 60
Cdd:smart00432   1 GRRKIEIKRIENKTNRQVTFSKRRNGLFKKAHELSVLCDAEVALIVFSPTGKLYEFASP 59
MADS cd00120
MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic ...
 2-60 6.36e-27

MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type II. These subgroups differ mainly in position of the alpha 2 helix responsible for the dimerization interface; Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238067 [Multi-domain]  Cd Length: 59  Bit Score: 100.67  E-value: 6.36e-27
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 2826142    2 GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASS 60
Cdd:cd00120   1 GRGKIEIKRIENKTSRQVTFSKRRNGLFKKASELSVLCDAEVAVIVFSPSGKLYEFWSS 59
MADS_SRF_like cd00266
SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) ...
 2-83 5.76e-24

SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in position of the alpha 2 helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238166 [Multi-domain]  Cd Length: 83  Bit Score: 93.86  E-value: 5.76e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    2 GRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDM-DRVLLKYTEYSEPHESRT 80
Cdd:cd00266   1 GRKKIKIKRIENKKKRAVTFSKRRQGLFKKASELSTLCGAEVAVIVYSPSGKLYVFWPSSEvEGVISRFEVLSALERKKK 80


                ...
gi 2826142   81 NAD 83
Cdd:cd00266  81 AVD 83
SRF-TF pfam00319
SRF-type transcription factor (DNA-binding and dimerization domain);
10-57 3.69e-23

SRF-type transcription factor (DNA-binding and dimerization domain);


Pssm-ID: 459760 [Multi-domain]  Cd Length: 48  Bit Score: 90.56  E-value: 3.69e-23
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2826142     10 RILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQY 57
Cdd:pfam00319   1 RIENKRARQVTFSKRRKGLFKKASELSVLCGAEVAVIVFSPTGKLYTF 48
ARG80 COG5068
Regulator of arginine metabolism and related MADS box-containing transcription factors ...
 1-206 5.82e-10

Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription];


Pssm-ID: 227400 [Multi-domain]  Cd Length: 412  Bit Score: 60.03  E-value: 5.82e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVL------LKYTEYSE 74
Cdd:COG5068  81 VTGRKIGISYITNKTKRSVTFSKRKHGINKKAFELSVLTGTEVLLLVISENGLVHTFTTPKLESVVkslegkSLIQSPCS 160

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142   75 PHESRTNADILQTLKRRGVGLDGPELDMEEGPEGPGEKLLRTLGGDRGSASPRPRiYPVAPAMSVSELSYRVPPATPgcd 154
Cdd:COG5068 161 NAPSDSSEEPSSSASFSVDPNDNNPMGSFQHNGSPQTNFIPLQNPQTQQYQQHSS-RKDHPTVPHSNTNNGRPPAKF--- 236

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|...
gi 2826142  155 pgglgEVPSVHSRPAYFR-PPGLGHPIFSPSHLASKTPPPLYLATDGRRPDLP 206
Cdd:COG5068 237 -----MIPELHSSHSTLDlPSDFISDSGFPNQSSTSIFPLDSAIIQITPPHLP 284
PHA03247 PHA03247
large tegument protein UL36; Provisional
 124-339 1.55e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 1.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    124 ASPRPRIYPVAPAMSVSELSYRVPPATPGCDPGGLGEVPSVHSRPAYFRPPGLGHPIFSPSHLASKTPPPLYLATDGRRP 203
Cdd:PHA03247 2737 AAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAA 2816

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    204 DLPPGLVGARGGLGTSRSLysglqsPGAPGPALGSFA-FLPSGSTDCSPGDAAQGPlqPSPWPPTRDAVdPARPVARSLC 282
Cdd:PHA03247 2817 ALPPAASPAGPLPPPTSAQ------PTAPPPPPGPPPpSLPLGGSVAPGGDVRRRP--PSRSPAAKPAA-PARPPVRRLA 2887

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2826142    283 KEGPPSRGASPPTPPVSIKSERlSPVTGTSGDFPRSFPYPLLLARPLAEPLRPSASL 339
Cdd:PHA03247 2888 RPAVSRSTESFALPPDQPERPP-QPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPL 2943
PHA03247 PHA03247
large tegument protein UL36; Provisional
 131-348 1.25e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.16  E-value: 1.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    131 YPVAPAmsvselsYRVPP-------ATPGCDPGGLGEvpsvhSRPAYFRPPGLGHPIFSPSHLASKTPPPLY-------- 195
Cdd:PHA03247 2474 FPGAPV-------YRRPAearfpfaAGAAPDPGGGGP-----PDPDAPPAPSRLAPAILPDEPVGEPVHPRMltwirgle 2541

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    196 -LATD---GRRPDLPPGLVGArgglGTSRSLYSGLQSPGAPGPALGSFAFLPS-------GSTDCSPGDAAQGPLQPSPW 264
Cdd:PHA03247 2542 eLASDdagDPPPPLPPAAPPA----APDRSVPPPRPAPRPSEPAVTSRARRPDappqsarPRAPVDDRGDPRGPAPPSPL 2617

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    265 PPTRDAVDPARPVARSLCKEGPPSRGASPPTPPVSIKSERLSPVTgtsgdFPRSfpyplllARPLAEPLRPSASLHRLTP 344
Cdd:PHA03247 2618 PPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVS-----RPRR-------ARRLGRAAQASSPPQRPRR 2685


                  ....
gi 2826142    345 DSWP 348
Cdd:PHA03247 2686 RAAR 2689
PHA03247 PHA03247
large tegument protein UL36; Provisional
 115-348 2.09e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 2.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    115 RTLGGDRGS------------ASPRPRIYPVAPAMSVSELSYRVPPATPGCDPGGLGEVPSVHSRP----AYFRPPGLGH 178
Cdd:PHA03247 2599 RAPVDDRGDprgpappsplppDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPrrarRLGRAAQASS 2678

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    179 PIFSPSHLASktPPPLYLATDGRRPDLPPGLVGARgglgtSRSLYSGLQSPGAPGPALGSFAFLPSGSTDCSPGDAAQGP 258
Cdd:PHA03247 2679 PPQRPRRRAA--RPTVGSLTSLADPPPPPPTPEPA-----PHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATP 2751

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    259 LQPSPWPPTRDAVDPARPVARSLCKEGPPSRGASPPTPPVSIKSERLsPVTGTSGDFPRSFPYPLLLARPLAEPLRPSAS 338
Cdd:PHA03247 2752 GGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESL-PSPWDPADPPAAVLAPAAALPPAASPAGPLPP 2830

                         250
                  ....*....|
gi 2826142    339 LHRLTPDSWP 348
Cdd:PHA03247 2831 PTSAQPTAPP 2840
PHA03247 PHA03247
large tegument protein UL36; Provisional
 94-344 2.55e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 2.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142     94 GLDGPELDMEEGPEGPGEKLLRTLGGDRGSASPRPRIYPVAPAMSVSELSYRVPPA-----TPGCDPGGL-GEVPSVHSR 167
Cdd:PHA03247 2539 GLEELASDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQsarprAPVDDRGDPrGPAPPSPLP 2618

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    168 PAYFRPPGlghPIFSPSHLASKTPPPLYLATDGR-RPDLPPglvgARGGLGTSRSLYSGLQSPGAPGPALG--SFAFLPS 244
Cdd:PHA03247 2619 PDTHAPDP---PPPSPSPAANEPDPHPPPTVPPPeRPRDDP----APGRVSRPRRARRLGRAAQASSPPQRprRRAARPT 2691

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    245 GSTDCSPGDAAQGPLQPSPWPPTRDAVDPARPVARSLCKEGPPSRGASPPTPPVSikserlSPVTGTSGDFPRSFPYPLL 324
Cdd:PHA03247 2692 VGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPA------GPATPGGPARPARPPTTAG 2765

                         250       260
                  ....*....|....*....|
gi 2826142    325 LARPLAEPLRPSASLHRLTP 344
Cdd:PHA03247 2766 PPAPAPPAAPAAGPPRRLTR 2785
PHA03247 PHA03247
large tegument protein UL36; Provisional
 121-343 4.45e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.15  E-value: 4.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    121 RGSASPRPRIYPVAPAMSVSELSYRVPPATPGCDPGGLGEVPSVhSRPAYFRPPGLGHPIFSPSHLASKTPPPLYlatdg 200
Cdd:PHA03247 2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAA-ALPPAASPAGPLPPPTSAQPTAPPPPPGPP----- 2846

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    201 rRPDLPPGLVGARGG----LGTSRSLYSGLQSPG----------APGPALGSFAFLPSGSTDCSPGDAAQGPLQPSPWPP 266
Cdd:PHA03247 2847 -PPSLPLGGSVAPGGdvrrRPPSRSPAAKPAAPArppvrrlarpAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPP 2925

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2826142    267 TRDAVDPARPVARSLCKEGPPSRGASPPTPPVSIKSERLSPVTGTSGDFPRSFPYPLLLARPLAEPLRPSASLHRLT 343
Cdd:PHA03247 2926 PPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLS 3002
PHA03247 PHA03247
large tegument protein UL36; Provisional
 126-348 5.02e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.15  E-value: 5.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    126 PRPRIY----PVAPAMSVSELSYRVPPATPGCDPGGLGEV-PSVHSRPAyfRPPglghpifSPSHLASKTPPPLYLATDG 200
Cdd:PHA03247 2710 PAPHALvsatPLPPGPAAARQASPALPAAPAPPAVPAGPAtPGGPARPA--RPP-------TTAGPPAPAPPAAPAAGPP 2780

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142    201 RRPDLPPGLVGARgglgTSRSLYSGLQSPGAPGPALGSFAFLPSGSTDCSPGDAAQGPLQPSPwPPTRDAVDPARPVARS 280
Cdd:PHA03247 2781 RRLTRPAVASLSE----SRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAP-PPPPGPPPPSLPLGGS 2855

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2826142    281 LCKEGPPSRGASPPTPPVSIKSERLSPVTGTSGDFPRSFPYPLLLARPLAEPLRPSASLHRLTPDSWP 348
Cdd:PHA03247 2856 VAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQP 2923
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
113-348 5.03e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 38.70  E-value: 5.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142   113 LLRTL-------GGDRGSAS----PRPRIYPVAPAMSVSELSYRVPPATPGCDPGGLGEVPSVHSRPayfrppglghpif 181
Cdd:PRK12323 357 LLRMLafrpgqsGGGAGPATaaaaPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAP------------- 423

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142   182 spshlASKTPPPLYLATDGRRPDLPPGlvGARGGLGTSRSLYSGLQSPGAPGPALGSFAFLPSGSTDCSPGDAAQGPLQP 261
Cdd:PRK12323 424 -----ARRSPAPEALAAARQASARGPG--GAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDP 496

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2826142   262 SPW---PPT--RDAVDPARPVARSLCKEGPPSRGASPPTPPVSIKSERLSPVtgtsgdfprSFPYPLLLARPLAEPLRPS 336
Cdd:PRK12323 497 PPWeelPPEfaSPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAA---------PAPRAAAATEPVVAPRPPR 567

                        250
                 ....*....|....*
gi 2826142   337 ASLHRLTPDS---WP 348
Cdd:PRK12323 568 ASASGLPDMFdgdWP 582
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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