NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|10434747|dbj|BAB14362|]
View 

unnamed protein product [Homo sapiens]

Protein Classification

RCC1 domain-containing protein( domain architecture ID 11474102)

RCC1 (regulator of chromosome condensation) domain-containing protein similar to Arabidopsis UVR8 (UV RESISTANCE LOCUS 8), which plays an important role in mediating the effects of UV-B radiation on pathogen resistance by controlling the expression of the sinapate biosynthetic pathway.

Gene Ontology:  GO:0003682|GO:0005085
PubMed:  9510255|18442486

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
39-216 9.78e-26

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


:

Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 106.21  E-value: 9.78e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747  39 GGKTVLQAALGVKHGVLLTEDGEVYSFG----------TLLWRSGPVEICPSSPilenalvgqyVITVATGSFHSGAVTD 108
Cdd:COG5184 147 GLSGVVAIAAGGYHTCALKSDGTVWCWGansygqlgdgTTTDRPTPVQVGGLSG----------VVAVAAGGDHSCALKS 216
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747 109 NGVAYMWGENSAGQCAVANQQYVPEPNPVSiadseasplLAVRILQLACGEEHTLALSISREIWAWG--TGCQLGLITTA 186
Cdd:COG5184 217 DGTVWCWGSNSSGQLGDGTTTDRATPVQVA---------GLTGVVAIAAGGSHTCALKSDGTVWCWGdnSYGQLGDGTTT 287
                       170       180       190
                ....*....|....*....|....*....|
gi 10434747 187 fPVTKPQKVEHLAGrvVLQVACGAFHSLAL 216
Cdd:COG5184 288 -DRSTPVKVPGLSG--VVAVAAGSSHTCAL 314
 
Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
39-216 9.78e-26

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 106.21  E-value: 9.78e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747  39 GGKTVLQAALGVKHGVLLTEDGEVYSFG----------TLLWRSGPVEICPSSPilenalvgqyVITVATGSFHSGAVTD 108
Cdd:COG5184 147 GLSGVVAIAAGGYHTCALKSDGTVWCWGansygqlgdgTTTDRPTPVQVGGLSG----------VVAVAAGGDHSCALKS 216
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747 109 NGVAYMWGENSAGQCAVANQQYVPEPNPVSiadseasplLAVRILQLACGEEHTLALSISREIWAWG--TGCQLGLITTA 186
Cdd:COG5184 217 DGTVWCWGSNSSGQLGDGTTTDRATPVQVA---------GLTGVVAIAAGGSHTCALKSDGTVWCWGdnSYGQLGDGTTT 287
                       170       180       190
                ....*....|....*....|....*....|
gi 10434747 187 fPVTKPQKVEHLAGrvVLQVACGAFHSLAL 216
Cdd:COG5184 288 -DRSTPVKVPGLSG--VVAVAAGSSHTCAL 314
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
170-216 2.31e-09

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 52.52  E-value: 2.31e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 10434747   170 EIWAWG--TGCQLGLITTAfPVTKPQKVEHLAGRVVLQVACGAFHSLAL 216
Cdd:pfam00415   3 RVYTWGrnDYGQLGLGTTE-NVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
 
Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
39-216 9.78e-26

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 106.21  E-value: 9.78e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747  39 GGKTVLQAALGVKHGVLLTEDGEVYSFG----------TLLWRSGPVEICPSSPilenalvgqyVITVATGSFHSGAVTD 108
Cdd:COG5184 147 GLSGVVAIAAGGYHTCALKSDGTVWCWGansygqlgdgTTTDRPTPVQVGGLSG----------VVAVAAGGDHSCALKS 216
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747 109 NGVAYMWGENSAGQCAVANQQYVPEPNPVSiadseasplLAVRILQLACGEEHTLALSISREIWAWG--TGCQLGLITTA 186
Cdd:COG5184 217 DGTVWCWGSNSSGQLGDGTTTDRATPVQVA---------GLTGVVAIAAGGSHTCALKSDGTVWCWGdnSYGQLGDGTTT 287
                       170       180       190
                ....*....|....*....|....*....|
gi 10434747 187 fPVTKPQKVEHLAGrvVLQVACGAFHSLAL 216
Cdd:COG5184 288 -DRSTPVKVPGLSG--VVAVAAGSSHTCAL 314
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
31-216 2.19e-23

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 99.67  E-value: 2.19e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747  31 TPERLPGwgGKTVLQAALGVKHGVLLTEDGEVYSFG----------TLLWRSGPVEIcpssPILENalvgqyVITVATGS 100
Cdd:COG5184  40 TPVRVPG--LSNVVAVAAGGDHTCALKADGTVWCWGnnsygqlgdgTTTDRTTPVKV----PGLTG------VVAVAAGY 107
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747 101 FHSGAVTDNGVAYMWGENSAGQcaVANQQYVPEPNPVSIADSeaspllAVRILQLACGEEHTLALSISREIWAWG--TGC 178
Cdd:COG5184 108 YHSCALKSDGTVWCWGDNSSGQ--LGDGTTTNRLTPVQVDAG------LSGVVAIAAGGYHTCALKSDGTVWCWGanSYG 179
                       170       180       190
                ....*....|....*....|....*....|....*...
gi 10434747 179 QLGLITTAfPVTKPQKVEHLAGrvVLQVACGAFHSLAL 216
Cdd:COG5184 180 QLGDGTTT-DRPTPVQVGGLSG--VVAVAAGGDHSCAL 214
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
31-219 6.17e-22

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 95.81  E-value: 6.17e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747  31 TPERLPGWGGktVLQAALGVKHGVLLTEDGEVYSFG----------TLLWRSGPVEICPSspiLENalvgqyVITVATGS 100
Cdd:COG5184  90 TPVKVPGLTG--VVAVAAGYYHSCALKSDGTVWCWGdnssgqlgdgTTTNRLTPVQVDAG---LSG------VVAIAAGG 158
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747 101 FHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSeaspllavrILQLACGEEHTLALSISREIWAWGTG--C 178
Cdd:COG5184 159 YHTCALKSDGTVWCWGANSYGQLGDGTTTDRPTPVQVGGLSG---------VVAVAAGGDHSCALKSDGTVWCWGSNssG 229
                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*.
gi 10434747 179 QLGLITTAFPVTkPQKVEHLAGrvVLQVACGAFHSLAL-----VQC 219
Cdd:COG5184 230 QLGDGTTTDRAT-PVQVAGLTG--VVAIAAGGSHTCALksdgtVWC 272
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
45-216 2.28e-20

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 91.19  E-value: 2.28e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747  45 QAALGVKHGVLLTEDGEVYSFG----------TLLWRSGPVEIcpssPILENalvgqyVITVATGSFHSGAVTDNGVAYM 114
Cdd:COG5184   2 QVAAGGSHSCALKSDGTVWCWGdnsygqlgdgTTTDRSTPVRV----PGLSN------VVAVAAGGDHTCALKADGTVWC 71
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747 115 WGENSAGQCAVANQQYVPEPNPVSIADSeaspllavrILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAfPVTKP 192
Cdd:COG5184  72 WGNNSYGQLGDGTTTDRTTPVKVPGLTG---------VVAVAAGYYHSCALKSDGTVWCWGDNSsgQLGDGTTT-NRLTP 141
                       170       180
                ....*....|....*....|....
gi 10434747 193 QKVEHLAGRVVlQVACGAFHSLAL 216
Cdd:COG5184 142 VQVDAGLSGVV-AIAAGGYHTCAL 164
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
94-216 9.21e-18

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 83.49  E-value: 9.21e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747  94 ITVATGSFHSGAVTDNGVAYMWGENSAGQcaVANQQYVPEPNPVSIADSEaspllavRILQLACGEEHTLALSISREIWA 173
Cdd:COG5184   1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQ--LGDGTTTDRSTPVRVPGLS-------NVVAVAAGGDHTCALKADGTVWC 71
                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*
gi 10434747 174 WGTGC--QLGLITTAFPVTkPQKVEHLAGrvVLQVACGAFHSLAL 216
Cdd:COG5184  72 WGNNSygQLGDGTTTDRTT-PVKVPGLTG--VVAVAAGYYHSCAL 113
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
31-189 1.31e-17

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 83.10  E-value: 1.31e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747  31 TPERLPGWGGktVLQAALGVKHGVLLTEDGEVYSFG----------TLLWRSGPVEICPSSPilenalvgqyVITVATGS 100
Cdd:COG5184 191 TPVQVGGLSG--VVAVAAGGDHSCALKSDGTVWCWGsnssgqlgdgTTTDRATPVQVAGLTG----------VVAIAAGG 258
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10434747 101 FHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADseaspllavRILQLACGEEHTLALSISREIWAWGTGC-- 178
Cdd:COG5184 259 SHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLS---------GVVAVAAGSSHTCALLTDGTVWCWGDNAyg 329
                       170
                ....*....|....
gi 10434747 179 QLGLITT---AFPV 189
Cdd:COG5184 330 QLGDGTTtdrSTPV 343
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
170-216 2.31e-09

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 52.52  E-value: 2.31e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 10434747   170 EIWAWG--TGCQLGLITTAfPVTKPQKVEHLAGRVVLQVACGAFHSLAL 216
Cdd:pfam00415   3 RVYTWGrnDYGQLGLGTTE-NVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
93-122 3.65e-06

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 43.18  E-value: 3.65e-06
                          10        20        30
                  ....*....|....*....|....*....|
gi 10434747    93 VITVATGSFHSGAVTDNGVAYMWGENSAGQ 122
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
109-165 2.24e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 41.35  E-value: 2.24e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 10434747   109 NGVAYMWGENSAGQCAVANQQYVPEPNPVSIadseaspLLAVRILQLACGEEHTLAL 165
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEG-------LSGNKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
152-175 9.68e-03

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 33.55  E-value: 9.68e-03
                          10        20
                  ....*....|....*....|....
gi 10434747   152 ILQLACGEEHTLALSISREIWAWG 175
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWG 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH