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Conserved domains on  [gi|10440136|dbj|BAB15656|]
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unnamed protein product [Homo sapiens]

Protein Classification

THO complex subunit 7 family protein( domain architecture ID 10528924)

THO complex subunit 7 (THOC7) family protein is a component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA

Gene Ontology:  GO:0006397|GO:0008380|GO:0003723|GO:0000346|GO:0000347
PubMed:  12871933
TCDB:  3.A.22

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
THOC7 pfam05615
Tho complex subunit 7; The Tho complex is involved in transcription elongation and mRNA export ...
 7-139 8.09e-46

Tho complex subunit 7; The Tho complex is involved in transcription elongation and mRNA export from the nucleus.


:

Pssm-ID: 461692 [Multi-domain]  Cd Length: 135  Bit Score: 147.80  E-value: 8.09e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10440136     7 DEVIRKRLLIDGDGAGGDRRINLLVKSFIKWCNS--GSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKI 84
Cdd:pfam05615   1 DELIKRRLLNDGLGLGEERPLKRLTKRFLKLCNSldSTPEEIQALREDLLLDLAAFELSIEKSQLLAEANERERENYEAE 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 10440136    85 YKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKEL 139
Cdd:pfam05615  81 KEEIEEEIEAVREEIEELKERLEEAKRTRKNREEYDALAEKINENPSREETEKQL 135
 
Name Accession Description Interval E-value
THOC7 pfam05615
Tho complex subunit 7; The Tho complex is involved in transcription elongation and mRNA export ...
 7-139 8.09e-46

Tho complex subunit 7; The Tho complex is involved in transcription elongation and mRNA export from the nucleus.


Pssm-ID: 461692 [Multi-domain]  Cd Length: 135  Bit Score: 147.80  E-value: 8.09e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10440136     7 DEVIRKRLLIDGDGAGGDRRINLLVKSFIKWCNS--GSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKI 84
Cdd:pfam05615   1 DELIKRRLLNDGLGLGEERPLKRLTKRFLKLCNSldSTPEEIQALREDLLLDLAAFELSIEKSQLLAEANERERENYEAE 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 10440136    85 YKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKEL 139
Cdd:pfam05615  81 KEEIEEEIEAVREEIEELKERLEEAKRTRKNREEYDALAEKINENPSREETEKQL 135
 
Name Accession Description Interval E-value
THOC7 pfam05615
Tho complex subunit 7; The Tho complex is involved in transcription elongation and mRNA export ...
 7-139 8.09e-46

Tho complex subunit 7; The Tho complex is involved in transcription elongation and mRNA export from the nucleus.


Pssm-ID: 461692 [Multi-domain]  Cd Length: 135  Bit Score: 147.80  E-value: 8.09e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10440136     7 DEVIRKRLLIDGDGAGGDRRINLLVKSFIKWCNS--GSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKI 84
Cdd:pfam05615   1 DELIKRRLLNDGLGLGEERPLKRLTKRFLKLCNSldSTPEEIQALREDLLLDLAAFELSIEKSQLLAEANERERENYEAE 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 10440136    85 YKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKEL 139
Cdd:pfam05615  81 KEEIEEEIEAVREEIEELKERLEEAKRTRKNREEYDALAEKINENPSREETEKQL 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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