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Conserved domains on  [gi|12854006|dbj|BAB29903|]
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unnamed protein product [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SYCE1 super family cl21095
Synaptonemal complex central element protein 1; This family of proteins includes synaptonemal ...
 45-130 7.87e-35

Synaptonemal complex central element protein 1; This family of proteins includes synaptonemal complex central element protein 1, a component of the synaptonemal complex involved in meiosis, and synaptonemal complex central element protein 1-like, which may be involved in meiosis.


The actual alignment was detected with superfamily member pfam15233:

Pssm-ID: 464575 [Multi-domain]  Cd Length: 152  Bit Score: 121.84  E-value: 7.87e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12854006    45 GSLEPQIEDLIHRINELQQgpAKKRSSEELGEAQALQEAMHRELDSLNEERVHLEEVLRKKQEAVSILKKHPQERDSDTP 124
Cdd:pfam15233   1 GSLEPQIEDLINRINELQQ--AKKKSSEELGEAQALWEALQRELDSLNGEKVHLEEVLNKKQEALRILQLHCQEKESEAQ 78


                  ....*.
gi 12854006   125 QKCTVQ 130
Cdd:pfam15233  79 RQHTLN 84
 
Name Accession Description Interval E-value
SYCE1 pfam15233
Synaptonemal complex central element protein 1; This family of proteins includes synaptonemal ...
 45-130 7.87e-35

Synaptonemal complex central element protein 1; This family of proteins includes synaptonemal complex central element protein 1, a component of the synaptonemal complex involved in meiosis, and synaptonemal complex central element protein 1-like, which may be involved in meiosis.


Pssm-ID: 464575 [Multi-domain]  Cd Length: 152  Bit Score: 121.84  E-value: 7.87e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12854006    45 GSLEPQIEDLIHRINELQQgpAKKRSSEELGEAQALQEAMHRELDSLNEERVHLEEVLRKKQEAVSILKKHPQERDSDTP 124
Cdd:pfam15233   1 GSLEPQIEDLINRINELQQ--AKKKSSEELGEAQALWEALQRELDSLNGEKVHLEEVLNKKQEALRILQLHCQEKESEAQ 78


                  ....*.
gi 12854006   125 QKCTVQ 130
Cdd:pfam15233  79 RQHTLN 84
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
5-114 5.51e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 37.59  E-value: 5.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12854006    5 LEPLMAEWlgaEKAEDTRGQAASLNTMEDLLETVKKLQKEGSLEPQIEDLIHRINELQQgpAKKRSSEELGEAQALQEAM 84
Cdd:COG4913  254 LEPIRELA---ERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEA--ELERLEARLDALREELDEL 328

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 12854006   85 HR--------ELDSLNEERVHLEEVLRKKQEAVSILKK 114
Cdd:COG4913  329 EAqirgnggdRLEQLEREIERLERELEERERRRARLEA 366
 
Name Accession Description Interval E-value
SYCE1 pfam15233
Synaptonemal complex central element protein 1; This family of proteins includes synaptonemal ...
 45-130 7.87e-35

Synaptonemal complex central element protein 1; This family of proteins includes synaptonemal complex central element protein 1, a component of the synaptonemal complex involved in meiosis, and synaptonemal complex central element protein 1-like, which may be involved in meiosis.


Pssm-ID: 464575 [Multi-domain]  Cd Length: 152  Bit Score: 121.84  E-value: 7.87e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12854006    45 GSLEPQIEDLIHRINELQQgpAKKRSSEELGEAQALQEAMHRELDSLNEERVHLEEVLRKKQEAVSILKKHPQERDSDTP 124
Cdd:pfam15233   1 GSLEPQIEDLINRINELQQ--AKKKSSEELGEAQALWEALQRELDSLNGEKVHLEEVLNKKQEALRILQLHCQEKESEAQ 78


                  ....*.
gi 12854006   125 QKCTVQ 130
Cdd:pfam15233  79 RQHTLN 84
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
5-114 5.51e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 37.59  E-value: 5.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12854006    5 LEPLMAEWlgaEKAEDTRGQAASLNTMEDLLETVKKLQKEGSLEPQIEDLIHRINELQQgpAKKRSSEELGEAQALQEAM 84
Cdd:COG4913  254 LEPIRELA---ERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEA--ELERLEARLDALREELDEL 328

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 12854006   85 HR--------ELDSLNEERVHLEEVLRKKQEAVSILKK 114
Cdd:COG4913  329 EAqirgnggdRLEQLEREIERLERELEERERRRARLEA 366
ATG16 pfam08614
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ...
 21-107 6.31e-03

Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.


Pssm-ID: 462536 [Multi-domain]  Cd Length: 176  Bit Score: 36.45  E-value: 6.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12854006    21 TRGQAAS-LNTMEDLLETVKKLQKEgsLEPQIEDLIHRINELQQgpAKKRSSEELGEAQALQEAMHRELDSLNEERVHLE 99
Cdd:pfam08614  72 SRGELAQrLVDLNEELQELEKKLRE--DERRLAALEAERAQLEE--KLKDREEELREKRKLNQDLQDELVALQLQLNMAE 147


                  ....*...
gi 12854006   100 EVLRKKQE 107
Cdd:pfam08614 148 EKLRKLEK 155
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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