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Conserved domains on  [gi|13359669|dbj|BAB33636|]
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hypothetical protein ECs_0213 [Escherichia coli O157:H7 str. Sakai]

Protein Classification

lysozyme inhibitor LprI family protein( domain architecture ID 878)

lysozyme inhibitor LprI family protein similar to Mycobacterium tuberculosis lipoprotein LprI, which acts as a lysozyme Inhibitor

CATH:  1.20.1270.180
PubMed:  18369469|26589796

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LprI super family cl01530
Lysozyme inhibitor LprI; This family consists of several bacterial proteins of around 120 ...
1-133 9.28e-04

Lysozyme inhibitor LprI; This family consists of several bacterial proteins of around 120 residues in length. Members of this family contain four highly conserved cysteine residues. Family members include lipoprotein LprI from Mycobacterium, which binds to and inhibits macrophage lysozyme, which may aid bacterial survival.


The actual alignment was detected with superfamily member COG3755:

Pssm-ID: 470238  Cd Length: 121  Bit Score: 36.98  E-value: 9.28e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13359669   1 MRKITIILLLTFSCTKGLAFDIsmskEC-SGVDELEFIDCVKNSFIMSTITLKKAEANIKEKIQKwnsdedeairKEAvi 79
Cdd:COG3755   1 MKKLLLLALLLLASLSALAQAA----DCdNAQTQAEMNACAAKEYQKADKELNKAYKALMKRLSA----------PEA-- 64
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 13359669  80 sLKRLESSNREFIRYRFAQCSFTLTwGARVGRLAFSRLYPCYTELNKIRAMQLN 133
Cdd:COG3755  65 -KAALRKAQRAWIKYRDAECAFAAA-AYEGGSIAPLAYASCLARLTQERTKELE 116
 
Name Accession Description Interval E-value
YecT COG3755
Uncharacterized conserved protein YecT, DUF1311 family [Function unknown];
1-133 9.28e-04

Uncharacterized conserved protein YecT, DUF1311 family [Function unknown];


Pssm-ID: 442969  Cd Length: 121  Bit Score: 36.98  E-value: 9.28e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13359669   1 MRKITIILLLTFSCTKGLAFDIsmskEC-SGVDELEFIDCVKNSFIMSTITLKKAEANIKEKIQKwnsdedeairKEAvi 79
Cdd:COG3755   1 MKKLLLLALLLLASLSALAQAA----DCdNAQTQAEMNACAAKEYQKADKELNKAYKALMKRLSA----------PEA-- 64
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 13359669  80 sLKRLESSNREFIRYRFAQCSFTLTwGARVGRLAFSRLYPCYTELNKIRAMQLN 133
Cdd:COG3755  65 -KAALRKAQRAWIKYRDAECAFAAA-AYEGGSIAPLAYASCLARLTQERTKELE 116
 
Name Accession Description Interval E-value
YecT COG3755
Uncharacterized conserved protein YecT, DUF1311 family [Function unknown];
1-133 9.28e-04

Uncharacterized conserved protein YecT, DUF1311 family [Function unknown];


Pssm-ID: 442969  Cd Length: 121  Bit Score: 36.98  E-value: 9.28e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 13359669   1 MRKITIILLLTFSCTKGLAFDIsmskEC-SGVDELEFIDCVKNSFIMSTITLKKAEANIKEKIQKwnsdedeairKEAvi 79
Cdd:COG3755   1 MKKLLLLALLLLASLSALAQAA----DCdNAQTQAEMNACAAKEYQKADKELNKAYKALMKRLSA----------PEA-- 64
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 13359669  80 sLKRLESSNREFIRYRFAQCSFTLTwGARVGRLAFSRLYPCYTELNKIRAMQLN 133
Cdd:COG3755  65 -KAALRKAQRAWIKYRDAECAFAAA-AYEGGSIAPLAYASCLARLTQERTKELE 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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