|
Name |
Accession |
Description |
Interval |
E-value |
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
43-345 |
2.92e-19 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 88.05 E-value: 2.92e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 43 RERCEELRVELLSIHQKKVCEERKAQIAFNEELSRQKLVEEQMFSKLWEEDRLAKEKREAQEARRQKELMENTRLGLNAQ 122
Cdd:pfam13868 2 RENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 123 ITSIKAQRQATQLLKEEEARLVESNNAQIKHENEQDMLKKQKAKQETRTILQKALQERIEHIQQEYRDEQDLNMKLVQRA 202
Cdd:pfam13868 82 IEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEYL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 203 LQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEEKAQEKEFDRILEEDKAKKLAEKDKELRLEKEARRQLVDEVMCTR 282
Cdd:pfam13868 162 KEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQAR 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16552943 283 KLQVQEKLQREAKEQEERAMEQKHINESLKELNCEEKENFARRQRLAQEYRKQLQMQIAYQQQ 345
Cdd:pfam13868 242 EEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREE 304
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
40-332 |
1.54e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 59.95 E-value: 1.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 40 QQFRERCEELRVELLSIHQKKVCEERKAQIAFNEELSRQKLVEEQMFSKLweEDRLAKEKREAQEARRQKELMENTRLGL 119
Cdd:COG1196 216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAEL--EAELEELRLELEELELELEEAQAEEYEL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 120 NAQITSIKAQRQATQLLKEEEARLVESNNAQIKHENEQdmLKKQKAKQETRTILQKALQERIEHIQQEYRDEQDlNMKLV 199
Cdd:COG1196 294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEE--LEELEEELEELEEELEEAEEELEEAEAELAEAEE-ALLEA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 200 QRALQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEEKAQEKEFDRILEEDKAKKLAEKDKELRLEKEARRQLVDEVM 279
Cdd:COG1196 371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 16552943 280 CTRKLQVQEKLQREAKEQEERAMEQKHINESLKELNCEEKENFARRQRLAQEY 332
Cdd:COG1196 451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
4-339 |
3.89e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.45 E-value: 3.89e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 4 KKETIEEKKDRMREKTKLLKEKNEKERQDFVAEKLDQQFRERCEELRvellsihqKKVCEERKAQIAFNEELSRQKlvee 83
Cdd:PTZ00121 1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAK--------KAAEAKKKADEAKKAEEAKKA---- 1524
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 84 qmfsklwEEDRLAKEKREAQEARRQKELMENTRLGLNAQITSIKAQRQATQLLKEEEARLVESNNAQI-----KHENEQD 158
Cdd:PTZ00121 1525 -------DEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEakkaeEARIEEV 1597
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 159 MLKKQKAKQETRTILQKALQERIEhiQQEYRDEQDLNMKLVQraLQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEE 238
Cdd:PTZ00121 1598 MKLYEEEKKMKAEEAKKAEEAKIK--AEELKKAEEEKKKVEQ--LKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 239 KAQEKEFDRILEEDK--AKKLAEKDKELRLEKEARRQLVDEVMCTRKLQVQEKLQREAKEQEERAMEQKhiNESLKELNC 316
Cdd:PTZ00121 1674 KKKAEEAKKAEEDEKkaAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED--KKKAEEAKK 1751
|
330 340
....*....|....*....|...
gi 16552943 317 EEKENFARRQRLAQEYRKQLQMQ 339
Cdd:PTZ00121 1752 DEEEKKKIAHLKKEEEKKAEEIR 1774
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
43-345 |
2.92e-19 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 88.05 E-value: 2.92e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 43 RERCEELRVELLSIHQKKVCEERKAQIAFNEELSRQKLVEEQMFSKLWEEDRLAKEKREAQEARRQKELMENTRLGLNAQ 122
Cdd:pfam13868 2 RENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEEQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 123 ITSIKAQRQATQLLKEEEARLVESNNAQIKHENEQDMLKKQKAKQETRTILQKALQERIEHIQQEYRDEQDLNMKLVQRA 202
Cdd:pfam13868 82 IEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEYL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 203 LQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEEKAQEKEFDRILEEDKAKKLAEKDKELRLEKEARRQLVDEVMCTR 282
Cdd:pfam13868 162 KEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQAR 241
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16552943 283 KLQVQEKLQREAKEQEERAMEQKHINESLKELNCEEKENFARRQRLAQEYRKQLQMQIAYQQQ 345
Cdd:pfam13868 242 EEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREE 304
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
40-332 |
1.54e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 59.95 E-value: 1.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 40 QQFRERCEELRVELLSIHQKKVCEERKAQIAFNEELSRQKLVEEQMFSKLweEDRLAKEKREAQEARRQKELMENTRLGL 119
Cdd:COG1196 216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAEL--EAELEELRLELEELELELEEAQAEEYEL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 120 NAQITSIKAQRQATQLLKEEEARLVESNNAQIKHENEQdmLKKQKAKQETRTILQKALQERIEHIQQEYRDEQDlNMKLV 199
Cdd:COG1196 294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEE--LEELEEELEELEEELEEAEEELEEAEAELAEAEE-ALLEA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 200 QRALQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEEKAQEKEFDRILEEDKAKKLAEKDKELRLEKEARRQLVDEVM 279
Cdd:COG1196 371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 16552943 280 CTRKLQVQEKLQREAKEQEERAMEQKHINESLKELNCEEKENFARRQRLAQEY 332
Cdd:COG1196 451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
97-366 |
1.50e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.79 E-value: 1.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 97 KEKREAQEARRQKELMENTRLGLNAQITSIKAQRQATQLLKEEEARLVESNNAQIKHENEQDMLKKQKAKQETRTILQKA 176
Cdd:COG1196 222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 177 LQERIEHIQQEYRDEQDLNMKLVQRALQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEEKAQEKEFDRILEEDKAKK 256
Cdd:COG1196 302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 257 LAEKDKELRLEKEARRQLVDEVmcTRKLQVQEKLQREAKEQEERAMEQKHINESLKELNCEEKENFARRQRLAQEYRKQL 336
Cdd:COG1196 382 EELAEELLEALRAAAELAAQLE--ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
|
250 260 270
....*....|....*....|....*....|
gi 16552943 337 QMQIAYQQQSQEAEKEEKRREFEAGVAANK 366
Cdd:COG1196 460 ALLELLAELLEEAALLEAALAELLEELAEA 489
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
4-339 |
3.89e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.45 E-value: 3.89e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 4 KKETIEEKKDRMREKTKLLKEKNEKERQDFVAEKLDQQFRERCEELRvellsihqKKVCEERKAQIAFNEELSRQKlvee 83
Cdd:PTZ00121 1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAK--------KAAEAKKKADEAKKAEEAKKA---- 1524
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 84 qmfsklwEEDRLAKEKREAQEARRQKELMENTRLGLNAQITSIKAQRQATQLLKEEEARLVESNNAQI-----KHENEQD 158
Cdd:PTZ00121 1525 -------DEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEakkaeEARIEEV 1597
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 159 MLKKQKAKQETRTILQKALQERIEhiQQEYRDEQDLNMKLVQraLQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEE 238
Cdd:PTZ00121 1598 MKLYEEEKKMKAEEAKKAEEAKIK--AEELKKAEEEKKKVEQ--LKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 239 KAQEKEFDRILEEDK--AKKLAEKDKELRLEKEARRQLVDEVMCTRKLQVQEKLQREAKEQEERAMEQKhiNESLKELNC 316
Cdd:PTZ00121 1674 KKKAEEAKKAEEDEKkaAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED--KKKAEEAKK 1751
|
330 340
....*....|....*....|...
gi 16552943 317 EEKENFARRQRLAQEYRKQLQMQ 339
Cdd:PTZ00121 1752 DEEEKKKIAHLKKEEEKKAEEIR 1774
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
4-339 |
2.69e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.75 E-value: 2.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 4 KKETIEEKKDRMREKTKLLKEKNEKERQDFVAEKLDQQFRERCEELRVEllSIHQKKVCEERKAQIAfnEELSRQKLVEE 83
Cdd:PTZ00121 1385 KKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKA--DEAKKKAEEAKKADEA--KKKAEEAKKAE 1460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 84 QMFSKLWEEDRLAKEKREAQEARRQKEL---MENTRLGLNAQITSIKAQRQATQLLKEEEARLVES--NNAQIKHENEQD 158
Cdd:PTZ00121 1461 EAKKKAEEAKKADEAKKKAEEAKKADEAkkkAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEakKAEEAKKADEAK 1540
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 159 MLKKQKAKQETRTILQKALQERIEHIQQEYRDEQDLNMKLvqRALQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEE 238
Cdd:PTZ00121 1541 KAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMAL--RKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 239 KAQEKEFDRILEEDKAKKLAEKDKELRLEKEARRQLVDEVMCTRKLQVQEKLQREAKEQEE---RAMEQKHINESLKELN 315
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEakkAEEDEKKAAEALKKEA 1698
|
330 340
....*....|....*....|....
gi 16552943 316 CEEKENFARRQRLAQEYRKQLQMQ 339
Cdd:PTZ00121 1699 EEAKKAEELKKKEAEEKKKAEELK 1722
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
4-317 |
6.66e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.13 E-value: 6.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 4 KKETIEEKKDRMREKTKLLKEKNEKERQDFV---AEKLDQQFRERCEELRV--ELLSIHQKKVCEERKAQIAFNEELSRQ 78
Cdd:PTZ00121 1509 KKKADEAKKAEEAKKADEAKKAEEAKKADEAkkaEEKKKADELKKAEELKKaeEKKKAEEAKKAEEDKNMALRKAEEAKK 1588
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 79 ---KLVEEQMFSKLWEEDRLAKEKREAQEARRQKELMENTRlglnaqitSIKAQRQATQLLKEEEARLVEsnnaQIKHEN 155
Cdd:PTZ00121 1589 aeeARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAE--------EEKKKVEQLKKKEAEEKKKAE----ELKKAE 1656
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 156 EQDMLKKQKAKQETRTILQKALQERIEHIQQEYRDEQDLNMKLVQRALQDLQEEADKKKQKREDMIREQKIYHKYLAQ-R 234
Cdd:PTZ00121 1657 EENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEaK 1736
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 235 REEEKAQEKEFDRILEEDKAKKLAEKDKELRLEKEARRQLVDEVMctrKLQVQEKLQREAKEQEERAMEQKHINESLKEL 314
Cdd:PTZ00121 1737 KEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVI---EEELDEEDEKRRMEVDKKIKDIFDNFANIIEG 1813
|
...
gi 16552943 315 NCE 317
Cdd:PTZ00121 1814 GKE 1816
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
100-308 |
9.31e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.44 E-value: 9.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 100 REAQEARRQKELMEntrlGLNAQITSIKAQRQATQLLKEEEARLV------ESNNAQIKHENEQDMLKKQKAKQETRTIL 173
Cdd:COG4913 242 EALEDAREQIELLE----PIRELAERYAAARERLAELEYLRAALRlwfaqrRLELLEAELEELRAELARLEAELERLEAR 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 174 QKALQERIEHIQQEYRDEQDLNMKLVQRALQDLQEEADKKKQKREDmireqkiYHKYLAQRREEEKAQEKEFDRILEEDK 253
Cdd:COG4913 318 LDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRAR-------LEALLAALGLPLPASAEEFAALRAEAA 390
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 16552943 254 AKKLAEKDKELRLEKEARRQLVDEvmctrklqVQEKLQREAKEQEERAMEQKHIN 308
Cdd:COG4913 391 ALLEALEEELEALEEALAEAEAAL--------RDLRRELRELEAEIASLERRKSN 437
|
|
| Nup88 |
pfam10168 |
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ... |
198-326 |
1.22e-03 |
|
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.
Pssm-ID: 462975 [Multi-domain] Cd Length: 713 Bit Score: 41.18 E-value: 1.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 198 LVQRALQDLQEEADKKK-------QKREDMIREQKIYHKYLAQRREEEKaqekefdRILEEDkAKKLAEKDKELRLEKEA 270
Cdd:pfam10168 536 LLSRATQVFREEYLKKHdlareeiQKRVKLLKLQKEQQLQELQSLEEER-------KSLSER-AEKLAEKYEEIKDKQEK 607
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 16552943 271 RRQLVDEVMCT--RKLQVQEKLQREAKEQEERAMEQ-KHINESLKELNceEKENFARRQ 326
Cdd:pfam10168 608 LMRRCKKVLQRlnSQLPVLSDAEREMKKELETINEQlKHLANAIKQAK--KKMNYQRYQ 664
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
23-335 |
1.48e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.88 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 23 KEKNEKERQDFVAEKLDQQFRERCEELRVEL-----LSIHQKKVCEERKAQIAFNEELSRQKLVEEQMFSKLWEEDRlak 97
Cdd:pfam17380 282 KAVSERQQQEKFEKMEQERLRQEKEEKAREVerrrkLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEER--- 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 98 eKREAQEARRQKELMENTRLgLNAQITSIKAQRQATQLLKEEEArlveSNNAQIKHENEQDMLKKQKAKQETRTILQKAL 177
Cdd:pfam17380 359 -KRELERIRQEEIAMEISRM-RELERLQMERQQKNERVRQELEA----ARKVKILEEERQRKIQQQKVEMEQIRAEQEEA 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 178 QERIEHIQQEYRDEQdlnMKLVQRALQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEEKAQEKEFDRILEEDKAKKL 257
Cdd:pfam17380 433 RQREVRRLEEERARE---MERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMI 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 258 AEKDKELRLEKEA--RRQLVDEVMCTRKLQVQEKLQREAKEQEERAMEQKHINESLKELNCEEKENFARRQRLAQEYRKQ 335
Cdd:pfam17380 510 EEERKRKLLEKEMeeRQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARA 589
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
27-334 |
2.28e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 40.51 E-value: 2.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 27 EKERQDFVAEKLDQQFRERCEELRVELLSIHQKKVCEERKAQIAFNEELSRQKLVEEQMFSKLWEEDRLAKEKREAQEAR 106
Cdd:PTZ00121 1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDAR 1164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 107 RQKELMENTRLGLNAQITSIKAQRQATQLLKEEEARLVEsnnAQIKHENEQDMLKKQKAKQETRTILQKALQERIEHIQQ 186
Cdd:PTZ00121 1165 KAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAE---AARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEE 1241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 187 EYRDEQDLNMKLVQR------ALQDLQEEADKKKQKRE-DMIREQKIYHKYLAQRREEEKAQEKEFDRILEE-DKAKKLA 258
Cdd:PTZ00121 1242 AKKAEEERNNEEIRKfeearmAHFARRQAAIKAEEARKaDELKKAEEKKKADEAKKAEEKKKADEAKKKAEEaKKADEAK 1321
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16552943 259 EKDKELRLEKEARRQLVDEVmcTRKLQVQEKLQREAKEQEERAMEQKHINESLKElncEEKENFARRQRLAQEYRK 334
Cdd:PTZ00121 1322 KKAEEAKKKADAAKKKAEEA--KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE---EAKKKADAAKKKAEEKKK 1392
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
8-337 |
2.36e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 40.34 E-value: 2.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 8 IEEKKDRMREKTKLLKEKNEKERQDFVAEKLDQQFRERCEELRVELLSIHQKKVCEERKAQIAFNEELSRQKLVEEQMFS 87
Cdd:pfam02463 671 LTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEE 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 88 KLWEEDRLAKEKREAQEARRQKELMENTRLGLNAQITSIKAQRQATQLLKEEEARLVESNNAQIKHENEQDMLKKQKAKQ 167
Cdd:pfam02463 751 EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKI 830
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 168 ETRTILQKALQERIEHIQQEYRDEQDLNMKLVQRALQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEEKAQEKEFDR 247
Cdd:pfam02463 831 KEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLN 910
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 248 ILEEDKAKKLAEKDKELRLEKEARRQLVDEVMCTRKLQVQEKLQREAKEQEERAMEQKhiNESLKELNCEEKENFARRQR 327
Cdd:pfam02463 911 LLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLA--KEELGKVNLMAIEEFEEKEE 988
|
330
....*....|
gi 16552943 328 LAQEYRKQLQ 337
Cdd:pfam02463 989 RYNKDELEKE 998
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
2-316 |
8.91e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 38.41 E-value: 8.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 2 QLKKETIEEKKDRMREKTKLLKEKNEKERQDFVAEKLDQQFRERCEELRVELLSIHQKKVCEERKAQIAFNEELSRQKLV 81
Cdd:pfam02463 198 QELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEE 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 82 EEQMFSKLWEEDRLAKEKREAQEARRQKELMENTRLG--LNAQITSIKAQRQATQLLKEEEARLVESNNAQIKHENEQDM 159
Cdd:pfam02463 278 EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEklKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEE 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16552943 160 LKKQKAKQET-RTILQKALQERIEHIQQEYRDEQDLNMKLVQRALQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEE 238
Cdd:pfam02463 358 EEELEKLQEKlEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEE 437
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16552943 239 KAQEKEFDRILEEDKAKKLAEKDKELRLEKEARRQLVDEVMCTRKLQVQEKLQREAKEQEERAMEQKHINESLKELNC 316
Cdd:pfam02463 438 SIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLAL 515
|
|
| |
