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Conserved domains on  [gi|30089314|dbj|BAC75872|]
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C4b-binding protein alpha-chain [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 1-256 8.90e-44

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 153.66  E-value: 8.90e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314    1 MTFTAALWVAVFGKCGPPPAIPNALPASDVNRTDFESH----TTLKYECLPGYgRGISRMTVYCKPSGE-WEISVSCAKK 75
Cdd:PHA02927   6 VTFLTLLGIGCVLSCCTIPSRPINMKFKNSVETDANANynigDTIEYLCLPGY-RKQKMGPIYAKCTGTgWTLFNQCIKR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314   76 HCRNPGYLDNGYVNGETITFGSQIEFSCQEGFILVGSSTSSCEVRGKG-VAWSNPFPECVIVKCGPPPDISNGKHSGTED 154
Cdd:PHA02927  85 RCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGSTGsMVWNPEAPICESVKCQSPPSISNGRHNGYED 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  155 FYPYNHGISYTCDPGFRLVGSPFIGCTVVNktvpvWsSSPPTCEKIICSQPNILHGVIVSGYKATYTHRDSVRLACLNGT 234
Cdd:PHA02927 165 FYTDGSVVTYSCNSGYSLIGNSGVLCSGGE-----W-SDPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGY 238

                        250       260
                 ....*....|....*....|...
gi 30089314  235 VLRGRHVIECQGNGNWS-SLPTC 256
Cdd:PHA02927 239 KLSGSSSSTCSPGNTWQpELPKC 261
C4bp_oligo pfam18453
Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization ...
 373-421 6.46e-24

Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization domain found in C4b-binding protein (C4BP), which contains 14 cysteines that form 7 intermolecular disulfide bridges. C4BP is a plasma glycoprotein complex of 570 kDa, which is mainly produced in the liver. C4BP is the major inhibitor of complement activation, the major isoform consists of 7alpha and one beta-chain where each alpha-chain comprises eight complement control domain proteins (CCPs) and a C-terminal oligomerization domain. This domain carries a stretch of 42-45 amino acids that has been shown to be required for ring formation.


:

Pssm-ID: 436513  Cd Length: 49  Bit Score: 93.66  E-value: 6.46e-24
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 30089314   373 EASEDLKPALTGNKTMQYVPNSHDVKMALEIYKLTLEVELLQLQIQKEK 421
Cdd:pfam18453   1 EFPEGCEQVLTGKKLMQCLPNPEDVKMALEVYKLSLEIELLELQIDKAK 49
PHA02831 super family cl31511
EEV host range protein; Provisional
 247-377 1.03e-15

EEV host range protein; Provisional


The actual alignment was detected with superfamily member PHA02831:

Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 76.95  E-value: 1.03e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  247 NGNWSSLPTC--EFDCDLPPAIVNGYYTSMV--YSKITLVTYECD----KGYRLVGKAIISCSFSKWKGTAPQCKAL-CQ 317
Cdd:PHA02831  63 NGSWSTKNMCigKRNCKDPVTILNGYIKNKKdqYSFGDSVTYACKvnklEKYSIVGNETVKCINKQWVPKYPVCKLIrCK 142

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  318 KPEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRCEQEASED 377
Cdd:PHA02831 143 YPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVKDKVHN 202
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 1-256 8.90e-44

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 153.66  E-value: 8.90e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314    1 MTFTAALWVAVFGKCGPPPAIPNALPASDVNRTDFESH----TTLKYECLPGYgRGISRMTVYCKPSGE-WEISVSCAKK 75
Cdd:PHA02927   6 VTFLTLLGIGCVLSCCTIPSRPINMKFKNSVETDANANynigDTIEYLCLPGY-RKQKMGPIYAKCTGTgWTLFNQCIKR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314   76 HCRNPGYLDNGYVNGETITFGSQIEFSCQEGFILVGSSTSSCEVRGKG-VAWSNPFPECVIVKCGPPPDISNGKHSGTED 154
Cdd:PHA02927  85 RCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGSTGsMVWNPEAPICESVKCQSPPSISNGRHNGYED 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  155 FYPYNHGISYTCDPGFRLVGSPFIGCTVVNktvpvWsSSPPTCEKIICSQPNILHGVIVSGYKATYTHRDSVRLACLNGT 234
Cdd:PHA02927 165 FYTDGSVVTYSCNSGYSLIGNSGVLCSGGE-----W-SDPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGY 238

                        250       260
                 ....*....|....*....|...
gi 30089314  235 VLRGRHVIECQGNGNWS-SLPTC 256
Cdd:PHA02927 239 KLSGSSSSTCSPGNTWQpELPKC 261
C4bp_oligo pfam18453
Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization ...
 373-421 6.46e-24

Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization domain found in C4b-binding protein (C4BP), which contains 14 cysteines that form 7 intermolecular disulfide bridges. C4BP is a plasma glycoprotein complex of 570 kDa, which is mainly produced in the liver. C4BP is the major inhibitor of complement activation, the major isoform consists of 7alpha and one beta-chain where each alpha-chain comprises eight complement control domain proteins (CCPs) and a C-terminal oligomerization domain. This domain carries a stretch of 42-45 amino acids that has been shown to be required for ring formation.


Pssm-ID: 436513  Cd Length: 49  Bit Score: 93.66  E-value: 6.46e-24
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 30089314   373 EASEDLKPALTGNKTMQYVPNSHDVKMALEIYKLTLEVELLQLQIQKEK 421
Cdd:pfam18453   1 EFPEGCEQVLTGKKLMQCLPNPEDVKMALEVYKLSLEIELLELQIDKAK 49
PHA02831 PHA02831
EEV host range protein; Provisional
 247-377 1.03e-15

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 76.95  E-value: 1.03e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  247 NGNWSSLPTC--EFDCDLPPAIVNGYYTSMV--YSKITLVTYECD----KGYRLVGKAIISCSFSKWKGTAPQCKAL-CQ 317
Cdd:PHA02831  63 NGSWSTKNMCigKRNCKDPVTILNGYIKNKKdqYSFGDSVTYACKvnklEKYSIVGNETVKCINKQWVPKYPVCKLIrCK 142

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  318 KPEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRCEQEASED 377
Cdd:PHA02831 143 YPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVKDKVHN 202
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 138-198 6.06e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.17  E-value: 6.06e-12
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30089314 138 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTVVNKtvpvWSSSPPTCE 198
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG----WSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
138-197 6.72e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.51  E-value: 6.72e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314   138 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTVVNKtvpvWSSSPPTC 197
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGT----WSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 316-371 1.95e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.93  E-value: 1.95e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 30089314 316 CQKPEV-GNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRCE 371
Cdd:cd00033   1 CPPPPVpENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 138-197 9.44e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 54.07  E-value: 9.44e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314    138 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTvVNKTvpvWSSSPPTC 197
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCL-ENGT---WSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
319-370 3.94e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.50  E-value: 3.94e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 30089314   319 PEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRC 370
Cdd:pfam00084   5 PDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 319-370 3.27e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 3.27e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 30089314    319 PEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRC 370
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 1-256 8.90e-44

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 153.66  E-value: 8.90e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314    1 MTFTAALWVAVFGKCGPPPAIPNALPASDVNRTDFESH----TTLKYECLPGYgRGISRMTVYCKPSGE-WEISVSCAKK 75
Cdd:PHA02927   6 VTFLTLLGIGCVLSCCTIPSRPINMKFKNSVETDANANynigDTIEYLCLPGY-RKQKMGPIYAKCTGTgWTLFNQCIKR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314   76 HCRNPGYLDNGYVNGETITFGSQIEFSCQEGFILVGSSTSSCEVRGKG-VAWSNPFPECVIVKCGPPPDISNGKHSGTED 154
Cdd:PHA02927  85 RCPSPRDIDNGQLDIGGVDFGSSITYSCNSGYQLIGESKSYCELGSTGsMVWNPEAPICESVKCQSPPSISNGRHNGYED 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  155 FYPYNHGISYTCDPGFRLVGSPFIGCTVVNktvpvWsSSPPTCEKIICSQPNILHGVIVSGYKATYTHRDSVRLACLNGT 234
Cdd:PHA02927 165 FYTDGSVVTYSCNSGYSLIGNSGVLCSGGE-----W-SDPPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGY 238

                        250       260
                 ....*....|....*....|...
gi 30089314  235 VLRGRHVIECQGNGNWS-SLPTC 256
Cdd:PHA02927 239 KLSGSSSSTCSPGNTWQpELPKC 261
C4bp_oligo pfam18453
Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization ...
 373-421 6.46e-24

Oligomerization domain of C4b-binding protein alpha; This is the C-terminal oligomerization domain found in C4b-binding protein (C4BP), which contains 14 cysteines that form 7 intermolecular disulfide bridges. C4BP is a plasma glycoprotein complex of 570 kDa, which is mainly produced in the liver. C4BP is the major inhibitor of complement activation, the major isoform consists of 7alpha and one beta-chain where each alpha-chain comprises eight complement control domain proteins (CCPs) and a C-terminal oligomerization domain. This domain carries a stretch of 42-45 amino acids that has been shown to be required for ring formation.


Pssm-ID: 436513  Cd Length: 49  Bit Score: 93.66  E-value: 6.46e-24
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 30089314   373 EASEDLKPALTGNKTMQYVPNSHDVKMALEIYKLTLEVELLQLQIQKEK 421
Cdd:pfam18453   1 EFPEGCEQVLTGKKLMQCLPNPEDVKMALEVYKLSLEIELLELQIDKAK 49
PHA02639 PHA02639
EEV host range protein; Provisional
 76-256 1.53e-18

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 85.49  E-value: 1.53e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314   76 HCRNPGYLDNGYVNG--ETITFGSQIEFSCQEGFILVGSSTSSCEVRGKGVAWSNPFPECVIVKCGPPPDISNGKHSGTE 153
Cdd:PHA02639  21 YCDKPDDISNGFITElmEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKECNDPPSIINGKIYNKR 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  154 DFYPYNHGISYTCDP----GFRLVGSPFIGCTVVNKtvpvWSSSPPTCEKIICSQPNILHGVI--VSGYKATYtHRDSVR 227
Cdd:PHA02639 101 EMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKS----WKPDPPICKMINCRFPALQNGYIngIPSNKKFY-YKTRVG 175

                        170       180       190
                 ....*....|....*....|....*....|
gi 30089314  228 LACLNGTVLRGRHVIECQGNGNW-SSLPTC 256
Cdd:PHA02639 176 FSCKSGFDLVGEKYSTCNINATWfPSIPTC 205
PHA02831 PHA02831
EEV host range protein; Provisional
 247-377 1.03e-15

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 76.95  E-value: 1.03e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  247 NGNWSSLPTC--EFDCDLPPAIVNGYYTSMV--YSKITLVTYECD----KGYRLVGKAIISCSFSKWKGTAPQCKAL-CQ 317
Cdd:PHA02831  63 NGSWSTKNMCigKRNCKDPVTILNGYIKNKKdqYSFGDSVTYACKvnklEKYSIVGNETVKCINKQWVPKYPVCKLIrCK 142

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  318 KPEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRCEQEASED 377
Cdd:PHA02831 143 YPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVKDKVHN 202
PHA02639 PHA02639
EEV host range protein; Provisional
 138-380 4.20e-14

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 72.39  E-value: 4.20e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  138 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCtVVNKTVPVWSSSPPTCekiicsqpnilhgvivsgyk 217
Cdd:PHA02639  22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTC-IKDKNNAIWSNKAPFC-------------------- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  218 atythrdsvrlaclngtVLRgrhviecqgngnwsslptcefDCDLPPAIVNG--YYTSMVYSKITLVTYECD--KG--YR 291
Cdd:PHA02639  81 -----------------MLK---------------------ECNDPPSIINGkiYNKREMYKVGDEIYYVCNehKGvqYS 122

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  292 LVGKAIISCSFSK-WKGTAPQCKAL-CQKPEVGNGTLSD--EKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEV 367
Cdd:PHA02639 123 LVGNEKITCIQDKsWKPDPPICKMInCRFPALQNGYINGipSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSI 202

                        250
                 ....*....|....*..
gi 30089314  368 PRCEQEASED----LKP 380
Cdd:PHA02639 203 PTCVRNKPIDdiiyLKP 219
PHA02817 PHA02817
EEV Host range protein; Provisional
 260-370 5.76e-13

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 68.04  E-value: 5.76e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  260 CDLPPAIVNG--YYTSMVYSKITLVTYECDKG-----YRLVGKAIISCSFS-KWKGTAPQCKAL-CQKPEVGNGTLS--- 327
Cdd:PHA02817  24 CCYPPSIKNGyiYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDgKWNKEFPVCKIIrCRFPALQNGFVNgip 103

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 30089314  328 DEKDQYVESEnVTIQCDSGFAMLGSQSISCSESGTWYPEVPRC 370
Cdd:PHA02817 104 DSKKFYYESE-VSFSCKPGFVLIGTKYSVCGINSSWIPKVPIC 145
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 138-198 6.06e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.17  E-value: 6.06e-12
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30089314 138 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTVVNKtvpvWSSSPPTCE 198
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG----WSPPPPTCE 57
PHA02831 PHA02831
EEV host range protein; Provisional
 31-224 2.39e-11

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 63.86  E-value: 2.39e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314   31 NRTdFESHTTLKYEClpgyGRGISRMTVYCKpSGEWEISVSC-AKKHCRNPGYLDNGYVNG--ETITFGSQIEFSCQ--- 104
Cdd:PHA02831  37 NKV-YEENENLEYKC----NNNFDKVFVTCN-NGSWSTKNMCiGKRNCKDPVTILNGYIKNkkDQYSFGDSVTYACKvnk 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  105 -EGFILVGSSTSSCeVRGKgvaWSNPFPECVIVKCGPPPdISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTVV 183
Cdd:PHA02831 111 lEKYSIVGNETVKC-INKQ---WVPKYPVCKLIRCKYPA-LQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDIN 185

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 30089314  184 NktvpVWSSSPPTCEKiicsqpNILHGVIVSGYKATYTHRD 224
Cdd:PHA02831 186 S----IWYPGIPKCVK------DKVHNEIQPNYLFDDLDED 216
Sushi pfam00084
Sushi repeat (SCR repeat);
138-197 6.72e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.51  E-value: 6.72e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314   138 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTVVNKtvpvWSSSPPTC 197
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGT----WSPPFPEC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 68-213 9.16e-11

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 61.50  E-value: 9.16e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314   68 ISVSCAKKHCRNPGYLDNGYV--NGETITFGSQIEFSCQEG-----FILVGSSTSSCEVRGKgvaWSNPFPECVIVKCGP 140
Cdd:PHA02817  15 VYSLCDLNKCCYPPSIKNGYIynKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGK---WNKEFPVCKIIRCRF 91

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30089314  141 PPdISNGKHSGTED---FYpYNHGISYTCDPGFRLVGSPFIGCTvVNKTvpvWSSSPPtcekiICSQPNILHGVIV 213
Cdd:PHA02817  92 PA-LQNGFVNGIPDskkFY-YESEVSFSCKPGFVLIGTKYSVCG-INSS---WIPKVP-----ICSRDNITYNKIY 156
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 316-371 1.95e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.93  E-value: 1.95e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 30089314 316 CQKPEV-GNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRCE 371
Cdd:cd00033   1 CPPPPVpENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 142-384 2.16e-10

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 61.64  E-value: 2.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  142 PDISNGKHSGTEDFYPYNHGISYTCDPGFRLVgSPFIGCTVVNktvpvWSSSPPtCEKIiCSQPNILHGVIvsgYKATYT 221
Cdd:PHA02954  24 PTMNNAKLTSTETSFNDKQKVTFTCDSGYYSL-DPNAVCETDK-----WKYENP-CKKM-CTVSDYVSELY---DKPLYE 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  222 HRDSVRLACLNGTvlRGRHVIECQGNGNWSSLPTCEFDCDLPPAIVNGYYTSMV--YSKITLVTYECDKGYRLVGKAIIS 299
Cdd:PHA02954  93 VNSTITLICKDET--KYFRCEEKNGNTSWNDTVTCPNAECQPLQLEHGSCQPVKekYSFGEHITINCDVGYEVIGASYIS 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  300 CSFSKWKgTAPQCKALCQKPEVGNGTLSDEKdqYVESENVTIQCDSGFAMLGSQSISCSEsGTWYPEVPRCEQeASEDLK 379
Cdd:PHA02954 171 CTANSWN-VIPSCQQKCDIPSLSNGLISGST--FSIGGVIHLSCKSGFTLTGSPSSTCID-GKWNPVLPICVR-SNEEFD 245


                 ....*
gi 30089314  380 PALTG 384
Cdd:PHA02954 246 PVDDG 250
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 77-134 8.65e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.39  E-value: 8.65e-10
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  77 CRNPGYLDNGYVNG--ETITFGSQIEFSCQEGFILVGSSTSSCEVRGKgvaWSNPFPECV 134
Cdd:cd00033   1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG---WSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 138-197 9.44e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 54.07  E-value: 9.44e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314    138 CGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTvVNKTvpvWSSSPPTC 197
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCL-ENGT---WSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 77-133 2.72e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.91  E-value: 2.72e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 30089314     77 CRNPGYLDNGYVNG--ETITFGSQIEFSCQEGFILVGSSTSSCEVRGKgvaWSNPFPEC 133
Cdd:smart00032   1 CPPPPDIENGTVTSssGTYSYGDTVTYSCDPGYTLIGSSTITCLENGT---WSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
319-370 3.94e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.50  E-value: 3.94e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 30089314   319 PEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRC 370
Cdd:pfam00084   5 PDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 260-313 1.57e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 50.54  E-value: 1.57e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 30089314 260 CDLPPAIVNGYYTSM--VYSKITLVTYECDKGYRLVGKAIISCSFS-KWKGTAPQCK 313
Cdd:cd00033   1 CPPPPVPENGTVTGSkgSYSYGSTVTYSCNEGYTLVGSSTITCTENgGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 202-257 2.06e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 50.54  E-value: 2.06e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 30089314 202 CSQPNILHGVIVSGYKATYTHRDSVRLACLNGTVLRGRHVIECQGNGNWS-SLPTCE 257
Cdd:cd00033   1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSpPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 319-370 3.27e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 3.27e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 30089314    319 PEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRC 370
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 260-312 7.45e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 48.68  E-value: 7.45e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 30089314    260 CDLPPAIVNGYYTSM--VYSKITLVTYECDKGYRLVGKAIISC-SFSKWKGTAPQC 312
Cdd:smart00032   1 CPPPPDIENGTVTSSsgTYSYGDTVTYSCDPGYTLIGSSTITClENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 202-256 1.97e-07

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 47.52  E-value: 1.97e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 30089314    202 CSQPNILHGVIVSGYKATYTHRDSVRLACLNGTVLRGRHVIECQGNGNWS-SLPTC 256
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSpPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
77-133 4.75e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 46.34  E-value: 4.75e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 30089314    77 CRNPGYLDNGYV--NGETITFGSQIEFSCQEGFILVGSSTSSCEVRGKgvaWSNPFPEC 133
Cdd:pfam00084   1 CPPPPDIPNGKVsaTKNEYNYGASVSYECDPGYRLVGSPTITCQEDGT---WSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
202-256 1.99e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.80  E-value: 1.99e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 30089314   202 CSQPNILHGVIVSGYKATYTHRDSVRLACLNGTVLRGRHVIECQGNGNWSSL-PTC 256
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPfPEC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 316-371 2.29e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 48.40  E-value: 2.29e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30089314  316 CQKPEVGNGTLSDEKDQYVESENVTIQCDSG-----FAMLGSQSISCSESGTWYPEVPRCE 371
Cdd:PHA02817  25 CYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCK 85
Sushi pfam00084
Sushi repeat (SCR repeat);
260-312 5.30e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 43.64  E-value: 5.30e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 30089314   260 CDLPPAIVNGYYTSM--VYSKITLVTYECDKGYRLVGKAIISCSFS-KWKGTAPQC 312
Cdd:pfam00084   1 CPPPPDIPNGKVSATknEYNYGASVSYECDPGYRLVGSPTITCQEDgTWSPPFPEC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 63-134 1.43e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 46.62  E-value: 1.43e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 30089314   63 SGEWEISVSCAKKhCRNPGyLDNGYVNGETITFGSQIEFSCQEGFILVGSSTSSCeVRGKgvaWSNPFPECV 134
Cdd:PHA02954 173 ANSWNVIPSCQQK-CDIPS-LSNGLISGSTFSIGGVIHLSCKSGFTLTGSPSSTC-IDGK---WNPVLPICV 238
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 1-259 2.90e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 45.85  E-value: 2.90e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314    1 MTFTAALWVAVFGKCGPPPAIPNALPASDvnrTDFESHTTLKYECLPGYGRgiSRMTVYCKpSGEWEISVSCaKKHCRNP 80
Cdd:PHA02954   7 VTLLCVLPAVVYSTCTVPTMNNAKLTSTE---TSFNDKQKVTFTCDSGYYS--LDPNAVCE-TDKWKYENPC-KKMCTVS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314   81 GYLDNGYvNGETITFGSQIEFSCQEGfilvgSSTSSCEVRGKGVAWSNPFpECVIVKCgPPPDISNGKHSGTEDFYPYNH 160
Cdd:PHA02954  80 DYVSELY-DKPLYEVNSTITLICKDE-----TKYFRCEEKNGNTSWNDTV-TCPNAEC-QPLQLEHGSCQPVKEKYSFGE 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  161 GISYTCDPGFRLVGSPFIGCTVVNktvpvWSSSPPTCEKiiCSQPNILHGVIvSGykATYTHRDSVRLACLNGTVLRGRH 240
Cdd:PHA02954 152 HITINCDVGYEVIGASYISCTANS-----WNVIPSCQQK--CDIPSLSNGLI-SG--STFSIGGVIHLSCKSGFTLTGSP 221

                        250       260
                 ....*....|....*....|....*
gi 30089314  241 VIECQgNGNWSS-LPTC-----EFD 259
Cdd:PHA02954 222 SSTCI-DGKWNPvLPICvrsneEFD 245
PHA02817 PHA02817
EEV Host range protein; Provisional
 14-134 9.61e-05

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 43.39  E-value: 9.61e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314   14 KCGPPPAIPNALPASdvNRTDFESHTTLKYEClPGYGRGI-----SRMTVYCKPSGEWEISVS-CAKKHCRNPGyLDNGY 87
Cdd:PHA02817  23 KCCYPPSIKNGYIYN--KKTEYNIGSNVTFFC-GNNTRGVrytlvGEKNIICEKDGKWNKEFPvCKIIRCRFPA-LQNGF 98

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 30089314   88 VNG----ETITFGSQIEFSCQEGFILVGSSTSSCEVRGkgvAWSNPFPECV 134
Cdd:PHA02817  99 VNGipdsKKFYYESEVSFSCKPGFVLIGTKYSVCGINS---SWIPKVPICS 146
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 15-70 2.43e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 38.66  E-value: 2.43e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 30089314     15 CGPPPAIPNALPASDvnRTDFESHTTLKYECLPGYgRGISRMTVYCKPSGEWEISV 70
Cdd:smart00032   1 CPPPPDIENGTVTSS--SGTYSYGDTVTYSCDPGY-TLIGSSTITCLENGTWSPPP 53
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 15-66 5.44e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 37.83  E-value: 5.44e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|..
gi 30089314  15 CGPPPAIPNALpaSDVNRTDFESHTTLKYECLPGYgRGISRMTVYCKPSGEW 66
Cdd:cd00033   1 CPPPPVPENGT--VTGSKGSYSYGSTVTYSCNEGY-TLVGSSTITCTENGGW 49
Sushi pfam00084
Sushi repeat (SCR repeat);
15-67 1.12e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 37.09  E-value: 1.12e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 30089314    15 CGPPPAIPNALPASdvNRTDFESHTTLKYECLPGYgRGISRMTVYCKPSGEWE 67
Cdd:pfam00084   1 CPPPPDIPNGKVSA--TKNEYNYGASVSYECDPGY-RLVGSPTITCQEDGTWS 50
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 260-371 5.01e-03

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 38.48  E-value: 5.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30089314  260 CDLPPAIVN-------GYYTSMVYSKITLVTYECDKGYRL--VGKAIISCSFSKWKGTAPQCKALCQKP-EVGNGTLSDE 329
Cdd:PHA02927  21 CTIPSRPINmkfknsvETDANANYNIGDTIEYLCLPGYRKqkMGPIYAKCTGTGWTLFNQCIKRRCPSPrDIDNGQLDIG 100

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 30089314  330 KDQYVESenVTIQCDSGFAMLGSQSISCSESGT----WYPEVPRCE 371
Cdd:PHA02927 101 GVDFGSS--ITYSCNSGYQLIGESKSYCELGSTgsmvWNPEAPICE 144
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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