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Conserved domains on  [gi|74145049|dbj|BAE22220|]
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unnamed protein product [Mus musculus]

Protein Classification

phosphatase PAP2 family protein( domain architecture ID 10130259)

phosphatase PAP2 family protein may be a histidine phosphatase that catalyzes the dephosphorylation of phospholipids such as phospholipid phosphatase 6 (PLPP6), or may be an inactive member such as PLPP7

CATH:  1.20.144.10
EC:  3.1.3.-
Gene Ontology:  GO:0016791|GO:0016311|GO:0008610
PubMed:  9122162|12447906|9260289
SCOP:  3001110|4001226

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PAP2_containing_2_like cd03391
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. ...
 97-255 1.51e-79

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a membrane-associated phosphatidic acid phosphatase.


:

Pssm-ID: 239485 [Multi-domain]  Cd Length: 159  Bit Score: 237.22  E-value: 1.51e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74145049  97 GVCAGRAASWASARSMVKLIGITGHGIPWIGGTILCLVRSSTLAGQEVLMNLLLALLLDIMTVAGVQKLIKRRGPYETSP 176
Cdd:cd03391   1 GVCARETSSWGPVRPLVKLLELSGHGIPWLAGTISCLWISSSPAGQEVLVNLLLGLLLDIITVAILKALVRRRRPAYNSP 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 74145049 177 GLLDYLTMDIYAFPAGHASRAAMVSKFFLSHLVLAVPLRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIGYFQFRLVE 255
Cdd:cd03391  81 DMLDYVAVDKYSFPSGHASRAAFVARFLLNHLVLAVPLRVLLVLWATVVGISRVLLGRHHVLDVLAGAFLGYLEALLVE 159
 
Name Accession Description Interval E-value
PAP2_containing_2_like cd03391
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. ...
 97-255 1.51e-79

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a membrane-associated phosphatidic acid phosphatase.


Pssm-ID: 239485 [Multi-domain]  Cd Length: 159  Bit Score: 237.22  E-value: 1.51e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74145049  97 GVCAGRAASWASARSMVKLIGITGHGIPWIGGTILCLVRSSTLAGQEVLMNLLLALLLDIMTVAGVQKLIKRRGPYETSP 176
Cdd:cd03391   1 GVCARETSSWGPVRPLVKLLELSGHGIPWLAGTISCLWISSSPAGQEVLVNLLLGLLLDIITVAILKALVRRRRPAYNSP 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 74145049 177 GLLDYLTMDIYAFPAGHASRAAMVSKFFLSHLVLAVPLRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIGYFQFRLVE 255
Cdd:cd03391  81 DMLDYVAVDKYSFPSGHASRAAFVARFLLNHLVLAVPLRVLLVLWATVVGISRVLLGRHHVLDVLAGAFLGYLEALLVE 159
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 100-249 3.72e-14

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 68.91  E-value: 3.72e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74145049 100 AGRAASWASARSMVKLIGITGHGIPWIGGTILCLVRSSTLAGQEVLMNLLLALLLDIMTVAGVQKLIKRRGPYETSPGLL 179
Cdd:COG0671  30 LLALLLLLLLLLALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAALLLLLLLLLLLLLKYLFGRPRPFVVPDLEL 109

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74145049 180 DYLTMDIYAFPAGHASRAAMVSkFFLSHLVLAVPLRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIGYF 249
Cdd:COG0671 110 LLGTAGGYSFPSGHAAAAFALA-LVLALLLPRRWLAALLLALALLVGLSRVYLGVHYPSDVLAGALLGLA 178
acidPPc smart00014
Acid phosphatase homologues;
165-249 1.38e-13

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 65.45  E-value: 1.38e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74145049    165 LIKRRGPYETSPGLL------DYLTMDIYAFPAGHASRAAMVS---KFFLSHLVLAVPLRVLLVLWAFCVGLSRVMIGRH 235
Cdd:smart00014  17 YFGRPRPFFLSIGDAcctpnfLLTLEAGYSFPSGHTAFAFAFAlflLLYLPARAGRKLLIFLLLLLALVVGFSRVYLGAH 96

                           90
                   ....*....|....
gi 74145049    236 HITDVISGFIIGYF 249
Cdd:smart00014  97 WPSDVLAGSLLGIL 110
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 187-249 6.42e-11

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 58.59  E-value: 6.42e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 74145049   187 YAFPAGHASRAAMVSkFFLSHLV------LAVPLRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIGYF 249
Cdd:pfam01569  46 YSFPSGHSATAFALA-LLLALLLrrlrkiVRVLLALLLLVLALLVGLSRLYLGVHFPSDVLAGALIGIL 113
PRK10699 PRK10699
phosphatidylglycerophosphatase B; Provisional
 187-246 9.19e-03

phosphatidylglycerophosphatase B; Provisional


Pssm-ID: 182658  Cd Length: 244  Bit Score: 36.55  E-value: 9.19e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 74145049  187 YAFPAGHASRAAmvskfflSHLVLAV----PLR-----VLLVLWAFCVGLSRVMIGRHHITDVISGFII 246
Cdd:PRK10699 157 FAFPSGHTMFAA-------SWALLAVgllwPRRryktvALLMLWATGVMGSRLLLGMHWPRDLVVATLI 218
 
Name Accession Description Interval E-value
PAP2_containing_2_like cd03391
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. ...
 97-255 1.51e-79

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a membrane-associated phosphatidic acid phosphatase.


Pssm-ID: 239485 [Multi-domain]  Cd Length: 159  Bit Score: 237.22  E-value: 1.51e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74145049  97 GVCAGRAASWASARSMVKLIGITGHGIPWIGGTILCLVRSSTLAGQEVLMNLLLALLLDIMTVAGVQKLIKRRGPYETSP 176
Cdd:cd03391   1 GVCARETSSWGPVRPLVKLLELSGHGIPWLAGTISCLWISSSPAGQEVLVNLLLGLLLDIITVAILKALVRRRRPAYNSP 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 74145049 177 GLLDYLTMDIYAFPAGHASRAAMVSKFFLSHLVLAVPLRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIGYFQFRLVE 255
Cdd:cd03391  81 DMLDYVAVDKYSFPSGHASRAAFVARFLLNHLVLAVPLRVLLVLWATVVGISRVLLGRHHVLDVLAGAFLGYLEALLVE 159
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 156-254 8.11e-17

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 74.42  E-value: 8.11e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74145049 156 IMTVAGVQKLIKRRGPYETSPGLLDYLTMDI----YAFPAGHASRAAMVS---KFFLSHLVLAVPLRVLLVLWAFCVGLS 228
Cdd:cd01610  16 LLLTGVLKYLFGRPRPYFLLRCGPDGDPLLLteggYSFPSGHAAFAFALAlflALLLPRRLLRLLLGLLLLLLALLVGLS 95

                        90       100
                ....*....|....*....|....*.
gi 74145049 229 RVMIGRHHITDVISGFIIGYFQFRLV 254
Cdd:cd01610  96 RVYLGVHYPSDVLAGALLGILVALLV 121
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 100-249 3.72e-14

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 68.91  E-value: 3.72e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74145049 100 AGRAASWASARSMVKLIGITGHGIPWIGGTILCLVRSSTLAGQEVLMNLLLALLLDIMTVAGVQKLIKRRGPYETSPGLL 179
Cdd:COG0671  30 LLALLLLLLLLLALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAALLLLLLLLLLLLLKYLFGRPRPFVVPDLEL 109

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74145049 180 DYLTMDIYAFPAGHASRAAMVSkFFLSHLVLAVPLRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIGYF 249
Cdd:COG0671 110 LLGTAGGYSFPSGHAAAAFALA-LVLALLLPRRWLAALLLALALLVGLSRVYLGVHYPSDVLAGALLGLA 178
acidPPc smart00014
Acid phosphatase homologues;
165-249 1.38e-13

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 65.45  E-value: 1.38e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74145049    165 LIKRRGPYETSPGLL------DYLTMDIYAFPAGHASRAAMVS---KFFLSHLVLAVPLRVLLVLWAFCVGLSRVMIGRH 235
Cdd:smart00014  17 YFGRPRPFFLSIGDAcctpnfLLTLEAGYSFPSGHTAFAFAFAlflLLYLPARAGRKLLIFLLLLLALVVGFSRVYLGAH 96

                           90
                   ....*....|....
gi 74145049    236 HITDVISGFIIGYF 249
Cdd:smart00014  97 WPSDVLAGSLLGIL 110
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 187-249 6.42e-11

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 58.59  E-value: 6.42e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 74145049   187 YAFPAGHASRAAMVSkFFLSHLV------LAVPLRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIGYF 249
Cdd:pfam01569  46 YSFPSGHSATAFALA-LLLALLLrrlrkiVRVLLALLLLVLALLVGLSRLYLGVHFPSDVLAGALIGIL 113
PAP2_like_4 cd03395
PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 187-247 8.16e-10

PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239489  Cd Length: 177  Bit Score: 56.50  E-value: 8.16e-10
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 74145049 187 YAFPAGHASRAAMVSkFFLSHLVLAVPLRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIG 247
Cdd:cd03395 104 YSFASSHAANSFALA-LFIWLFFRRGLFSPVLLLWALLVGYSRVYVGVHYPGDVIAGALIG 163
PAP2_wunen cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid ...
 189-247 1.76e-09

PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.


Pssm-ID: 239479  Cd Length: 150  Bit Score: 54.94  E-value: 1.76e-09
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 74145049 189 FPAGHASRA--AMV-------SKFFLSHLVLAVP-LRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIG 247
Cdd:cd03384  74 FPSGHASLSmyAAVflalylqARLKLRGSRLLRPlLQFLLLALALYVGLSRISDYKHHWSDVLAGALLG 142
PAP2_like_2 cd03392
PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 176-249 4.37e-09

PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239486  Cd Length: 182  Bit Score: 54.54  E-value: 4.37e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74145049 176 PGLLDYLTMDIYAFPAGHASRAAMVSKF-------FLSHLVLAVPLRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIGY 248
Cdd:cd03392  90 PPLHLLVPEGGYSFPSGHAMGATVLYGFlayllarRLPRRRVRILLLILAAILILLVGLSRLYLGVHYPSDVLAGWLLGL 169


                .
gi 74145049 249 F 249
Cdd:cd03392 170 A 170
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 189-249 1.05e-07

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 51.07  E-value: 1.05e-07
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 74145049 189 FPAGHASRAA--MV--SKFFLSHLVLAVP----LRVLLVLW----AFCVGLSRVMIGRHHITDVISGFIIGYF 249
Cdd:cd03390 112 FPSGHSSFAFagLGflSLYLAGKLHIFDPrgssWRLLLALLplllAILVAVSRTRDYRHHFSDVIAGSLIGLI 184
PAP2_SPPase1 cd03388
PAP2_like proteins, sphingosine-1-phosphatase subfamily. Sphingosine-1-phosphatase is an ...
 187-247 1.57e-06

PAP2_like proteins, sphingosine-1-phosphatase subfamily. Sphingosine-1-phosphatase is an intracellular enzyme located in the endoplasmic reticulum, which regulates the level of sphingosine-1-phosphate (S1P), a bioactive lipid. S1P acts as a second messenger in the cell, and extracellularly by binding to G-protein coupled receptors of the endothelial differentiation gene family.


Pssm-ID: 239482  Cd Length: 151  Bit Score: 46.84  E-value: 1.57e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 74145049 187 YAFPAGHASRAAMVSKFFLSHLVLAVP-----LRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIG 247
Cdd:cd03388  78 YGFPSTHAMNATAISFYLLIYLYDRYQypfvlGLILALFYSTLVCLSRIYMGMHSVLDVIAGSLIG 143
PAP2_lipid_A_1_phosphatase cd03389
PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from ...
 189-249 1.70e-06

PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from Francisella novicida selectively dephosphorylates lipid A at the 1-position. Lipid A is the membrane-anchor component of lipopolysaccharides (LPS), the major constituents of the outer membrane in many gram-negative bacteria.


Pssm-ID: 239483  Cd Length: 186  Bit Score: 47.32  E-value: 1.70e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 74145049 189 FPAGHASRA-AMVSKFFLshlvLAVPLRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIGYF 249
Cdd:cd03389 120 FPSGHSATAgAAAAALAL----LFPRYRWAFILLALLIAFSRVIVGAHYPSDVIAGSLLGAV 177
PAP2_like_5 cd03394
PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 189-254 5.77e-05

PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239488 [Multi-domain]  Cd Length: 106  Bit Score: 41.16  E-value: 5.77e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 74145049 189 FPAGHASRAAMVSKFF---LSHLVLAVPLRVLLVLwafcVGLSRVMIGRHHITDVISGFIIGYFQFRLV 254
Cdd:cd03394  41 FPSGHTASAFAAATFLqyrYGWRWYGIPAYALASL----VGASRVVANRHWLSDVLAGAAIGILVGYLV 105
PAP2_BcrC_like cd03385
PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as ...
 189-254 3.25e-04

PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from Bacillus subtilis posesses undecaprenyl pyrophosphate (UPP) phospatase activity, and it is hypothesized that it competes with bacitracin for UPP, increasing the cell's resistance to bacitracin.


Pssm-ID: 239480  Cd Length: 144  Bit Score: 39.93  E-value: 3.25e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 74145049 189 FPAGHASRAAMVS-KFFLSHLVLAvplRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIGYFQFRLV 254
Cdd:cd03385  79 FPSDHTTLFFSIAfSLLLRRRKWA---GWILLILALLVAWSRIYLGVHYPLDMLGAALVAVLSALLV 142
PAP2_Aur1_like cd03386
PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of ...
 188-257 8.33e-04

PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin.


Pssm-ID: 239481  Cd Length: 186  Bit Score: 39.22  E-value: 8.33e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74145049 188 AFPAGHASRAAMVSKFFLSHLvlAVPLRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIGYFQFRLVELV 257
Cdd:cd03386 118 AFPSLHVAWAVLAALFLWRHR--RRLLRWLAVLWPLLIWLSTLYLGNHYFIDLVGGIALALLSFYLARRV 185
PAP2_like_3 cd03393
PAP2_like_3 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 187-247 2.55e-03

PAP2_like_3 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria and archaea, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239487 [Multi-domain]  Cd Length: 125  Bit Score: 36.97  E-value: 2.55e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 74145049 187 YAFPAGHASRAAMVSKFFLSHLVLAVpLRVLLVLWAFCVGLSRVMIGRHHITDVISGFIIG 247
Cdd:cd03393  58 YGFPSGHAQTSATFWGSLMLHVRKKW-FTLIGVVLVVLISFSRLYLGVHWPSDVIGGVLIG 117
PRK10699 PRK10699
phosphatidylglycerophosphatase B; Provisional
 187-246 9.19e-03

phosphatidylglycerophosphatase B; Provisional


Pssm-ID: 182658  Cd Length: 244  Bit Score: 36.55  E-value: 9.19e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 74145049  187 YAFPAGHASRAAmvskfflSHLVLAV----PLR-----VLLVLWAFCVGLSRVMIGRHHITDVISGFII 246
Cdd:PRK10699 157 FAFPSGHTMFAA-------SWALLAVgllwPRRryktvALLMLWATGVMGSRLLLGMHWPRDLVVATLI 218
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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