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Conserved domains on  [gi|221042464|dbj|BAH12909|]
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unnamed protein product [Homo sapiens]

Protein Classification

flavin monoamine oxidase family protein( domain architecture ID 11440890)

flavin monoamine oxidase family protein functions as an oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.50.50.60|1.10.405.10
EC:  1.-.-.-
Gene Ontology:  GO:0000166|GO:0016491
SCOP:  4000128

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
1-357 1.70e-81

Monoamine oxidase [Amino acid transport and metabolism];


:

Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 256.77  E-value: 1.70e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464   1 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVK-YVDLGGSYVGPTQNRILRLAKELGLETYK-VNEVERLIHHVKG 78
Cdd:COG1231   20 LAAARELRKAGLDVTVLEARDRVGGRVWTLRFGDDGlYAELGAMRIPPSHTNLLALARELGLPLEPfPNENGNALLYLGG 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464  79 KSYPFRGpfppvwnpiTYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVT 158
Cdd:COG1231  100 KRVRAGE---------IAADLRGVAELLAKLLRALAAALDPWAHPAAELDRESLAEWLRRNGASPSARRLLGLLGAGEYG 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464 159 AETHEVSALWFLWYVKQCGGttriisttnGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEM 238
Cdd:COG1231  171 ADPDELSLLDLLRYAASAGG---------GAQQFRIVGGMDQLPRALAAELGDRIRLGAPVTRIRQDGDGVTVTTDDGGT 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464 239 YEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYtLDDTKPE 318
Cdd:COG1231  242 VRADAVIVTVPPSVLRRIEFDPPLPAAKRAAIQRLPYGAAIKVFLQFDRPFWEEDGLYGGISLTDLPIRQTW-YPSNGPD 320

                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 221042464 319 GNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLG 357
Cdd:COG1231  321 GGAGVLLGYVGGDDARALAALSPEERVAAALEQLARIFG 359
 
Name Accession Description Interval E-value
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
1-357 1.70e-81

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 256.77  E-value: 1.70e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464   1 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVK-YVDLGGSYVGPTQNRILRLAKELGLETYK-VNEVERLIHHVKG 78
Cdd:COG1231   20 LAAARELRKAGLDVTVLEARDRVGGRVWTLRFGDDGlYAELGAMRIPPSHTNLLALARELGLPLEPfPNENGNALLYLGG 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464  79 KSYPFRGpfppvwnpiTYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVT 158
Cdd:COG1231  100 KRVRAGE---------IAADLRGVAELLAKLLRALAAALDPWAHPAAELDRESLAEWLRRNGASPSARRLLGLLGAGEYG 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464 159 AETHEVSALWFLWYVKQCGGttriisttnGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEM 238
Cdd:COG1231  171 ADPDELSLLDLLRYAASAGG---------GAQQFRIVGGMDQLPRALAAELGDRIRLGAPVTRIRQDGDGVTVTTDDGGT 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464 239 YEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYtLDDTKPE 318
Cdd:COG1231  242 VRADAVIVTVPPSVLRRIEFDPPLPAAKRAAIQRLPYGAAIKVFLQFDRPFWEEDGLYGGISLTDLPIRQTW-YPSNGPD 320

                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 221042464 319 GNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLG 357
Cdd:COG1231  321 GGAGVLLGYVGGDDARALAALSPEERVAAALEQLARIFG 359
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 1-360 2.05e-52

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 181.15  E-value: 2.05e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464    1 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVkYVDLGGSYVGPTQNRILRLAKELGLET---YKVNEVERLIHHVK 77
Cdd:pfam01593   4 LAAARELLRAGHDVTVLEARDRVGGRIRTVRDDGF-LIELGAMWFHGAQPPLLALLKELGLEDrlvLPDPAPFYTVLFAG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464   78 GKSYPFRG-PFPPVWNPITYLDHN-------------NFWRTMDDMGREIPSDAPWKA-------PLAEEWDNMTMKELL 136
Cdd:pfam01593  83 GRRYPGDFrRVPAGWEGLLEFGRLlsipeklrlglaaLASDALDEFDLDDFSLAESLLflgrrgpGDVEVWDRLIDPELF 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464  137 DKLCWTesakqLATLFVNLCVTAEThevSALWFLWYVKQCGGTTRIIsttnggqerkfVGGSGQVSERI-MDLLGDRVKL 215
Cdd:pfam01593 163 AALPFA-----SGAFAGDPSELSAG---LALPLLWALLGEGGSLLLP-----------RGGLGALPDALaAQLLGGDVRL 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464  216 ERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDY 295
Cdd:pfam01593 224 NTRVRSIDREGDGVTVTLTDGEVIEADAVIVTVPLGVLKRILFTPPLPPEKARAIRNLGYGPVNKVHLEFDRKFWPDLGL 303

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 221042464  296 CGTMIIDGEEAPVAY---TLDDTKPEGNYAAIMGFI-LAHKARKLARLTKEERLKKLCELYAKVLGSLE 360
Cdd:pfam01593 304 LGLLSELLTGLGTAFswlTFPNRAPPGKGLLLLVYVgPGDRARELEGLSDEELLQAVLRDLRKLFGEEA 372
PLN02268 PLN02268
probable polyamine oxidase
 1-290 5.92e-09

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 57.39  E-value: 5.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464   1 MAAAKLLHDSGLNVVVLEARDRVGGRTYTlrnqkvKY-----VDLGGSYV-GPTQ-NRILRLAKELGLETYKVNeverli 73
Cdd:PLN02268  13 IAAARALHDASFKVTLLESRDRIGGRVHT------DYsfgfpVDMGASWLhGVCNeNPLAPLIGRLGLPLYRTS------ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464  74 hhvkGKsypfrgpfppvwNPITYlDHNNFWRTMDDM-GREIPSDAPWKaplAEEWDNMTMKE---LLDKLCWTESAKQLA 149
Cdd:PLN02268  81 ----GD------------NSVLY-DHDLESYALFDMdGNQVPQELVTK---VGETFERILEEtekVRDEHEEDMSLLQAI 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464 150 TLFVN----LCVTAETHEVsalwFLWYVKQCGG----TTRIISTTNGGQERKFVGGSGQVS---ERIMDLL--GDRVKLE 216
Cdd:PLN02268 141 SIVLErhpeLRLEGLAHEV----LQWYLCRMEGwfaaDADTISLKSWDQEELLEGGHGLMVrgyDPVINTLakGLDIRLN 216

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 221042464 217 RPVIYIDQTRENVLVETLNHEMYEAKYVISAIPptLGM----KIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFW 290
Cdd:PLN02268 217 HRVTKIVRRYNGVKVTVEDGTTFVADAAIIAVP--LGVlkanIIKFEPELPEWKEEAISDLGVGIENKIALHFDSVFW 292
 
Name Accession Description Interval E-value
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
1-357 1.70e-81

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 256.77  E-value: 1.70e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464   1 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVK-YVDLGGSYVGPTQNRILRLAKELGLETYK-VNEVERLIHHVKG 78
Cdd:COG1231   20 LAAARELRKAGLDVTVLEARDRVGGRVWTLRFGDDGlYAELGAMRIPPSHTNLLALARELGLPLEPfPNENGNALLYLGG 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464  79 KSYPFRGpfppvwnpiTYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVT 158
Cdd:COG1231  100 KRVRAGE---------IAADLRGVAELLAKLLRALAAALDPWAHPAAELDRESLAEWLRRNGASPSARRLLGLLGAGEYG 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464 159 AETHEVSALWFLWYVKQCGGttriisttnGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEM 238
Cdd:COG1231  171 ADPDELSLLDLLRYAASAGG---------GAQQFRIVGGMDQLPRALAAELGDRIRLGAPVTRIRQDGDGVTVTTDDGGT 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464 239 YEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYtLDDTKPE 318
Cdd:COG1231  242 VRADAVIVTVPPSVLRRIEFDPPLPAAKRAAIQRLPYGAAIKVFLQFDRPFWEEDGLYGGISLTDLPIRQTW-YPSNGPD 320

                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 221042464 319 GNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLG 357
Cdd:COG1231  321 GGAGVLLGYVGGDDARALAALSPEERVAAALEQLARIFG 359
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 1-360 2.05e-52

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 181.15  E-value: 2.05e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464    1 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVkYVDLGGSYVGPTQNRILRLAKELGLET---YKVNEVERLIHHVK 77
Cdd:pfam01593   4 LAAARELLRAGHDVTVLEARDRVGGRIRTVRDDGF-LIELGAMWFHGAQPPLLALLKELGLEDrlvLPDPAPFYTVLFAG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464   78 GKSYPFRG-PFPPVWNPITYLDHN-------------NFWRTMDDMGREIPSDAPWKA-------PLAEEWDNMTMKELL 136
Cdd:pfam01593  83 GRRYPGDFrRVPAGWEGLLEFGRLlsipeklrlglaaLASDALDEFDLDDFSLAESLLflgrrgpGDVEVWDRLIDPELF 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464  137 DKLCWTesakqLATLFVNLCVTAEThevSALWFLWYVKQCGGTTRIIsttnggqerkfVGGSGQVSERI-MDLLGDRVKL 215
Cdd:pfam01593 163 AALPFA-----SGAFAGDPSELSAG---LALPLLWALLGEGGSLLLP-----------RGGLGALPDALaAQLLGGDVRL 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464  216 ERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDY 295
Cdd:pfam01593 224 NTRVRSIDREGDGVTVTLTDGEVIEADAVIVTVPLGVLKRILFTPPLPPEKARAIRNLGYGPVNKVHLEFDRKFWPDLGL 303

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 221042464  296 CGTMIIDGEEAPVAY---TLDDTKPEGNYAAIMGFI-LAHKARKLARLTKEERLKKLCELYAKVLGSLE 360
Cdd:pfam01593 304 LGLLSELLTGLGTAFswlTFPNRAPPGKGLLLLVYVgPGDRARELEGLSDEELLQAVLRDLRKLFGEEA 372
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 2-251 3.15e-13

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 71.02  E-value: 3.15e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464   2 AAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKyVDLGG-SYVgPTQNRILRLAKELGLET--YKVNEVERLIHHvKG 78
Cdd:COG1232   15 TAAYRLAKAGHEVTVLEASDRVGGLIRTVEVDGFR-IDRGPhSFL-TRDPEVLELLRELGLGDelVWPNTRKSYIYY-GG 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464  79 KSYPF-RGPFPPVWNPItyLDhnnfWRTMDDMGREIpsDAPWKAPLAEE--------------WDNMtMKELLDKLcWTE 143
Cdd:COG1232   92 KLHPLpQGPLALLRSPL--LS----LAGKLRALLEL--LAPRRPPGEDEslaefvrrrfgrevYERL-VEPLLEGV-YAG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464 144 SAKQLatlfvnlcvtaethevSALWFLWYVKQ---------CGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGD-RV 213
Cdd:COG1232  162 DPDEL----------------SADWAFPRLKRlelehgsliKGALALRKGAKAGEVFGYLRGGLGTLVEALAEALEAgEI 225

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 221042464 214 KLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPT 251
Cdd:COG1232  226 RLGTRVTAIEREGGGWRVTTSDGETIEADAVVSATPAP 263
PLN02268 PLN02268
probable polyamine oxidase
 1-290 5.92e-09

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 57.39  E-value: 5.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464   1 MAAAKLLHDSGLNVVVLEARDRVGGRTYTlrnqkvKY-----VDLGGSYV-GPTQ-NRILRLAKELGLETYKVNeverli 73
Cdd:PLN02268  13 IAAARALHDASFKVTLLESRDRIGGRVHT------DYsfgfpVDMGASWLhGVCNeNPLAPLIGRLGLPLYRTS------ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464  74 hhvkGKsypfrgpfppvwNPITYlDHNNFWRTMDDM-GREIPSDAPWKaplAEEWDNMTMKE---LLDKLCWTESAKQLA 149
Cdd:PLN02268  81 ----GD------------NSVLY-DHDLESYALFDMdGNQVPQELVTK---VGETFERILEEtekVRDEHEEDMSLLQAI 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464 150 TLFVN----LCVTAETHEVsalwFLWYVKQCGG----TTRIISTTNGGQERKFVGGSGQVS---ERIMDLL--GDRVKLE 216
Cdd:PLN02268 141 SIVLErhpeLRLEGLAHEV----LQWYLCRMEGwfaaDADTISLKSWDQEELLEGGHGLMVrgyDPVINTLakGLDIRLN 216

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 221042464 217 RPVIYIDQTRENVLVETLNHEMYEAKYVISAIPptLGM----KIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFW 290
Cdd:PLN02268 217 HRVTKIVRRYNGVKVTVEDGTTFVADAAIIAVP--LGVlkanIIKFEPELPEWKEEAISDLGVGIENKIALHFDSVFW 292
PRK07233 PRK07233
hypothetical protein; Provisional
 2-252 1.09e-08

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 56.82  E-value: 1.09e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464   2 AAAKLLHDSGLNVVVLEARDRVGG--RTYTLRNQKV-KYvdlggsY--VGPTQNRILRLAKELGLEtykvnevERLI--- 73
Cdd:PRK07233  13 AAAYRLAKRGHEVTVFEADDQLGGlaASFEFGGLPIeRF------YhhIFKSDEALLELLDELGLE-------DKLRwre 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464  74 ----HHVKGKSYPFRGP-----FPPvWNPIT---------YLDHNNFWRTMDDMGreipsdapwkaplAEEWdnmtMKEL 135
Cdd:PRK07233  80 tktgYYVDGKLYPLGTPlellrFPH-LSLIDkfrlglltlLARRIKDWRALDKVP-------------AEEW----LRRW 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464 136 LDKLCWTESAKQL--ATLFVNlcvtaeTHEVSALWfLWyvkqcgGTTRIISTT--NGGQERK--FVGGSGQVSERIMDLL 209
Cdd:PRK07233 142 SGEGVYEVFWEPLleSKFGDY------ADDVSAAW-LW------SRIKRRGNRrySLFGEKLgyLEGGFATLIDALAEAI 208

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 221042464 210 GDR---VKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTL 252
Cdd:PRK07233 209 EARggeIRLGTPVTSVVIDGGGVTGVEVDGEEEDFDAVISTAPPPI 254
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
1-59 2.51e-08

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 50.22  E-value: 2.51e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464    1 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKyVDLGGSYV-GPTQNRILRLAKEL 59
Cdd:pfam13450   9 LVAAALLAKRGFRVLVLEKRDRLGGNAYSYRVPGYV-FDYGAHIFhGSDEPNVRDLLDEL 67
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 1-250 3.68e-08

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 55.24  E-value: 3.68e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464   1 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKyVDLGGSYVGPTQ--NRILRlakELGLETYkvneverlihhvkg 78
Cdd:COG1233   16 LAAAALLARAGYRVTVLEKNDTPGGRARTFERPGFR-FDVGPSVLTMPGvlERLFR---ELGLEDY-------------- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464  79 ksYPFRgPFPPVWNPI----TYLDhnnFWRTMDDMGREI----PSDAP--------------------WKAPLAEEWD-- 128
Cdd:COG1233   78 --LELV-PLDPAYRVPfpdgRALD---LPRDLERTAAELerlfPGDAEayrrflaelrrlydalledlLYRPLLSLRDll 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464 129 ------------NMTMKELLDKlcWTESAKqLATLF--VNLCVTAETHEVSAL-WFLWYVKQCGGTTRIisttnggqerk 193
Cdd:COG1233  152 rplalarllrllLRSLRDLLRR--YFKDPR-LRALLagQALYLGLSPDRTPALyALIAYLEYAGGVWYP----------- 217

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 221042464 194 fVGGSGQVSERIMDL---LGDRVKLERPV--IYIDQTREnVLVETLNHEMYEAKYVISAIPP 250
Cdd:COG1233  218 -KGGMGALADALARLaeeLGGEIRTGAEVerILVEGGRA-TGVRLADGEEIRADAVVSNADP 277
PLN03000 PLN03000
amine oxidase
 1-290 1.23e-07

amine oxidase


Pssm-ID: 178578 [Multi-domain]  Cd Length: 881  Bit Score: 53.87  E-value: 1.23e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464   1 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLR---NQKVKYVDLGGSYV-GPTQNRILRLAKELGLETYKVNEVERLiHHV 76
Cdd:PLN03000 197 LAAARQLMRFGFKVTVLEGRKRPGGRVYTKKmeaNRVGAAADLGGSVLtGTLGNPLGIIARQLGSSLYKVRDKCPL-YRV 275

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464  77 KGKsypfrgPFPPVWNPITYLDHNnfwRTMDD-------MGrEIPSDAPWKAPLaeewdnmtmkELLDKLCWTESAKQLA 149
Cdd:PLN03000 276 DGK------PVDPDVDLKVEVAFN---QLLDKasklrqlMG-DVSMDVSLGAAL----------ETFRQVSGNDVATEEM 335

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464 150 TLF----VNLcVTAETHEVSALWFLWYVKQcggttriISTTNGGQERKFVGGSGqvseRIMDLLGDRVKL--ERPVIYID 223
Cdd:PLN03000 336 GLFnwhlANL-EYANAGLVSKLSLAFWDQD-------DPYDMGGDHCFLPGGNG----RLVQALAENVPIlyEKTVQTIR 403

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 221042464 224 QTRENVLVeTLNHEMYEAKYVISAIPptLGM----KIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFW 290
Cdd:PLN03000 404 YGSNGVKV-IAGNQVYEGDMVLCTVP--LGVlkngSIKFVPELPQRKLDCIKRLGFGLLNKVAMLFPYVFW 471
PLN02676 PLN02676
polyamine oxidase
 1-64 5.14e-07

polyamine oxidase


Pssm-ID: 215362 [Multi-domain]  Cd Length: 487  Bit Score: 51.64  E-value: 5.14e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 221042464   1 MAAAKLLHDSGL-NVVVLEARDRVGGRTYTLRNQKVKyVDLGGSYV----GPTQNRILRLAKELGLETY 64
Cdd:PLN02676  39 ISAAKTLSEAGIeDILILEATDRIGGRMRKANFAGVS-VELGANWVegvgGPESNPIWELANKLKLRTF 106
PLN02328 PLN02328
lysine-specific histone demethylase 1 homolog
 1-69 2.47e-06

lysine-specific histone demethylase 1 homolog


Pssm-ID: 215187 [Multi-domain]  Cd Length: 808  Bit Score: 49.61  E-value: 2.47e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 221042464   1 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQK---VKYVDLGGSYV-GPTQNRILRLAKELGLETYKVNEV 69
Cdd:PLN02328 251 LVAARQLLSMGFKVVVLEGRARPGGRVKTMKMKGdgvVAAADLGGSVLtGINGNPLGVLARQLGLPLHKVRDI 323
PLN02529 PLN02529
lysine-specific histone demethylase 1
 1-68 3.15e-06

lysine-specific histone demethylase 1


Pssm-ID: 178144 [Multi-domain]  Cd Length: 738  Bit Score: 49.50  E-value: 3.15e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 221042464   1 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLR-NQKVKY--VDLGGSYV-GPTQNRILRLAKELGLETYKVNE 68
Cdd:PLN02529 173 LAAARQLLSFGFKVVVLEGRNRPGGRVYTQKmGRKGQFaaVDLGGSVItGIHANPLGVLARQLSIPLHKVRD 244
PLN02976 PLN02976
amine oxidase
 1-43 6.02e-06

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 48.71  E-value: 6.02e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 221042464    1 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGS 43
Cdd:PLN02976  706 LTAARHLQRQGFSVTVLEARSRIGGRVYTDRSSLSVPVDLGAS 748
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 2-81 1.47e-03

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 40.60  E-value: 1.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221042464   2 AAAKLLHDSGLN--VVVLEARDRVGGRTYTLRnQKVKYVDLGG-SYVGptqnR---ILRLAKELGLEtykvnevERLIHH 75
Cdd:PRK11883  14 SAAYRLHKKGPDadITLLEASDRLGGKIQTVR-KDGFPIELGPeSFLA----RkpsAPALVKELGLE-------DELVAN 81


                 ....*.
gi 221042464  76 VKGKSY 81
Cdd:PRK11883  82 TTGQSY 87
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 1-31 6.49e-03

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 38.68  E-value: 6.49e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 221042464   1 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLR 31
Cdd:COG3349   16 LAAAVELAEAGFRVTLLEARPRLGGRARSFP 46
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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