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Conserved domains on  [gi|3877056|emb|CAA85452|]
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UPAR/Ly6 domain-containing protein [Caenorhabditis elegans]

Protein Classification

Ly-6/uPAR domain-containing protein; Ly-6/uPAR domain-containing protein; acrosomal protein SP-10; acrosomal protein SP-10( domain architecture ID 10639047)

LU (Ly-6 antigen/uPA receptor-like) domain-containing protein similar to GPI-linked cell-surface glycoproteins (Ly-6 family, CD59, thymocyte B cell antigen, Sgp-2); LU (Ly-6 antigen/uPA receptor-like) domain-containing protein similar to GPI-linked cell-surface glycoproteins (Ly-6 family, CD59, thymocyte B cell antigen, Sgp-2); acrosomal protein SP-10 (ACRV1) is a testis-specific, intra-acrosomal protein that is associated with the membranes and matrix of the acrosomal vesicle; acrosomal protein SP-10 (ACRV1) is a testis-specific, intra-acrosomal protein that is associated with the membranes and matrix of the acrosomal vesicle

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LU smart00134
Ly-6 antigen / uPA receptor -like domain; Three-fold repeated domain in urokinase-type ...
 41-143 2.18e-07

Ly-6 antigen / uPA receptor -like domain; Three-fold repeated domain in urokinase-type plasminogen activator receptor; occurs singly in other GPI-linked cell-surface glycoproteins (Ly-6 family, CD59, thymocyte B cell antigen, Sgp-2). Topology of these domains is similar to that of snake venom neurotoxins.


:

Pssm-ID: 214530  Cd Length: 85  Bit Score: 46.76  E-value: 2.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3877056      41 YDCFSGFVGRMQAsvEENHFHindtamCSA--MYCIKVILHSALDDdgiFQQGISSRCAYtggdRQVCQKSEGkcqdiSF 118
Cdd:smart00134   1 LQCYSCTGNPDSS--CSSEEE------CRSpdDVCLTVVAEVISDS---RGSVVYKGCAT----SPICPGSHG-----YE 60

                           90       100
                   ....*....|....*....|....*
gi 3877056     119 YDGMKGNFSFCCCKENKCNVATQTE 143
Cdd:smart00134  61 INLTIAFLKVSCCQTDLCNAAGPGA 85
 
Name Accession Description Interval E-value
LU smart00134
Ly-6 antigen / uPA receptor -like domain; Three-fold repeated domain in urokinase-type ...
 41-143 2.18e-07

Ly-6 antigen / uPA receptor -like domain; Three-fold repeated domain in urokinase-type plasminogen activator receptor; occurs singly in other GPI-linked cell-surface glycoproteins (Ly-6 family, CD59, thymocyte B cell antigen, Sgp-2). Topology of these domains is similar to that of snake venom neurotoxins.


Pssm-ID: 214530  Cd Length: 85  Bit Score: 46.76  E-value: 2.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3877056      41 YDCFSGFVGRMQAsvEENHFHindtamCSA--MYCIKVILHSALDDdgiFQQGISSRCAYtggdRQVCQKSEGkcqdiSF 118
Cdd:smart00134   1 LQCYSCTGNPDSS--CSSEEE------CRSpdDVCLTVVAEVISDS---RGSVVYKGCAT----SPICPGSHG-----YE 60

                           90       100
                   ....*....|....*....|....*
gi 3877056     119 YDGMKGNFSFCCCKENKCNVATQTE 143
Cdd:smart00134  61 INLTIAFLKVSCCQTDLCNAAGPGA 85
 
Name Accession Description Interval E-value
LU smart00134
Ly-6 antigen / uPA receptor -like domain; Three-fold repeated domain in urokinase-type ...
 41-143 2.18e-07

Ly-6 antigen / uPA receptor -like domain; Three-fold repeated domain in urokinase-type plasminogen activator receptor; occurs singly in other GPI-linked cell-surface glycoproteins (Ly-6 family, CD59, thymocyte B cell antigen, Sgp-2). Topology of these domains is similar to that of snake venom neurotoxins.


Pssm-ID: 214530  Cd Length: 85  Bit Score: 46.76  E-value: 2.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3877056      41 YDCFSGFVGRMQAsvEENHFHindtamCSA--MYCIKVILHSALDDdgiFQQGISSRCAYtggdRQVCQKSEGkcqdiSF 118
Cdd:smart00134   1 LQCYSCTGNPDSS--CSSEEE------CRSpdDVCLTVVAEVISDS---RGSVVYKGCAT----SPICPGSHG-----YE 60

                           90       100
                   ....*....|....*....|....*
gi 3877056     119 YDGMKGNFSFCCCKENKCNVATQTE 143
Cdd:smart00134  61 INLTIAFLKVSCCQTDLCNAAGPGA 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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