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Conserved domains on  [gi|7268233|emb|CAB78529|]
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hypothetical protein [Arabidopsis thaliana]

Protein Classification

preprotein translocase subunit SecE( domain architecture ID 10002155)

preprotein translocase subunit SecE is an essential subunit of the Sec protein translocation channel SecYEG and it clamps together the 2 halves of SecY; may contact the channel plug during translocation

CATH:  1.20.5.1030
Gene Ontology:  GO:0043952|GO:0065002|GO:0006605
SCOP:  4005885
TCDB:  3.A.5

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SecE COG0690
Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular ...
 100-167 3.88e-06

Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 440454  Cd Length: 68  Bit Score: 42.51  E-value: 3.88e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7268233  100 MEQRKTAeeeKGKN--EFLSGVAEEVKEIEWPAFQKVLGTTGVVLGVIAGSSVVLLTVNFLLAELSDRVF 167
Cdd:COG0690   1 MAKKKTG---KGKKivKFFKEVRAELKKVVWPTRKELIQTTLVVLVFVLIFALFLWLVDLLFGWLVSLIL 67
Borrelia_P83 super family cl26956
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 45-135 1.65e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


The actual alignment was detected with superfamily member pfam05262:

Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 38.06  E-value: 1.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7268233     45 LRKSACFVAKAIE-QRRDTAGSESESEATPSPAEESGSGEDKEVEISAIGAEIKAAMEQRKTAEE-EKGKNEFLSGVAEE 122
Cdd:pfam05262 232 AQQKADFAQDNADkQRDEVRQKQQEAKNLPKPADTSSPKEDKQVAENQKREIEKAQIEIKKNDEEaLKAKDHKAFDLKQE 311

                          90
                  ....*....|...
gi 7268233    123 VKEIEWPAFQKVL 135
Cdd:pfam05262 312 SKASEKEAEDKEL 324
 
Name Accession Description Interval E-value
SecE COG0690
Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular ...
 100-167 3.88e-06

Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440454  Cd Length: 68  Bit Score: 42.51  E-value: 3.88e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7268233  100 MEQRKTAeeeKGKN--EFLSGVAEEVKEIEWPAFQKVLGTTGVVLGVIAGSSVVLLTVNFLLAELSDRVF 167
Cdd:COG0690   1 MAKKKTG---KGKKivKFFKEVRAELKKVVWPTRKELIQTTLVVLVFVLIFALFLWLVDLLFGWLVSLIL 67
secE PRK07597
preprotein translocase subunit SecE; Reviewed
 110-162 2.83e-04

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 236066  Cd Length: 64  Bit Score: 37.59  E-value: 2.83e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 7268233   110 KGKNEFLSGVAEEVKEIEWPAFQKVLGTTGVVLGVIAGSSVVLLTVNFLLAEL 162
Cdd:PRK07597   8 KKLKKFFKDVKAELKKVTWPTRKELVRSTIVVLVFVAFFALFFYLVDLLFSKL 60
secE_bact TIGR00964
preprotein translocase, SecE subunit, bacterial; This model represents exclusively the ...
 114-159 9.71e-04

preprotein translocase, SecE subunit, bacterial; This model represents exclusively the bacterial (and some organellar) SecE protein. SecE is part of the core heterotrimer, SecYEG, of the Sec preprotein translocase system. Other components are the ATPase SecA, a cytosolic chaperone SecB, and an accessory complex of SecDF and YajC. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273367  Cd Length: 55  Bit Score: 35.65  E-value: 9.71e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 7268233    114 EFLSGVAEEVKEIEWPAFQKVLGTTGVVLGVIAGSSVVLLTVNFLL 159
Cdd:TIGR00964   3 KFFKEVKAELKKVVWPSRKELITYTIVVIVFVLFFSLFLFGIDYVF 48
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 114-162 1.14e-03

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 35.48  E-value: 1.14e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 7268233    114 EFLSGVAEEVKEIEWPAFQKVLGTTGVVLGVIAGSSVVLLTVNFLLAEL 162
Cdd:pfam00584   2 KFFKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVDLGFSIL 50
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 45-135 1.65e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 38.06  E-value: 1.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7268233     45 LRKSACFVAKAIE-QRRDTAGSESESEATPSPAEESGSGEDKEVEISAIGAEIKAAMEQRKTAEE-EKGKNEFLSGVAEE 122
Cdd:pfam05262 232 AQQKADFAQDNADkQRDEVRQKQQEAKNLPKPADTSSPKEDKQVAENQKREIEKAQIEIKKNDEEaLKAKDHKAFDLKQE 311

                          90
                  ....*....|...
gi 7268233    123 VKEIEWPAFQKVL 135
Cdd:pfam05262 312 SKASEKEAEDKEL 324
PTZ00121 PTZ00121
MAEBL; Provisional
 30-127 2.50e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 37.81  E-value: 2.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7268233     30 VFPVYTEIRTMTTSNLRKSACFVAKAIEQRRDTAGSESESEATPSPAEESGSGED--KEVEISAIGA---------EIKA 98
Cdd:PTZ00121 1597 VMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEElkKAEEENKIKAaeeakkaeeDKKK 1676

                          90       100
                  ....*....|....*....|....*....
gi 7268233     99 AMEQRKTAEEEKGKNEFLSGVAEEVKEIE 127
Cdd:PTZ00121 1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAE 1705
 
Name Accession Description Interval E-value
SecE COG0690
Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular ...
 100-167 3.88e-06

Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440454  Cd Length: 68  Bit Score: 42.51  E-value: 3.88e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7268233  100 MEQRKTAeeeKGKN--EFLSGVAEEVKEIEWPAFQKVLGTTGVVLGVIAGSSVVLLTVNFLLAELSDRVF 167
Cdd:COG0690   1 MAKKKTG---KGKKivKFFKEVRAELKKVVWPTRKELIQTTLVVLVFVLIFALFLWLVDLLFGWLVSLIL 67
secE PRK07597
preprotein translocase subunit SecE; Reviewed
 110-162 2.83e-04

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 236066  Cd Length: 64  Bit Score: 37.59  E-value: 2.83e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 7268233   110 KGKNEFLSGVAEEVKEIEWPAFQKVLGTTGVVLGVIAGSSVVLLTVNFLLAEL 162
Cdd:PRK07597   8 KKLKKFFKDVKAELKKVTWPTRKELVRSTIVVLVFVAFFALFFYLVDLLFSKL 60
secE_bact TIGR00964
preprotein translocase, SecE subunit, bacterial; This model represents exclusively the ...
 114-159 9.71e-04

preprotein translocase, SecE subunit, bacterial; This model represents exclusively the bacterial (and some organellar) SecE protein. SecE is part of the core heterotrimer, SecYEG, of the Sec preprotein translocase system. Other components are the ATPase SecA, a cytosolic chaperone SecB, and an accessory complex of SecDF and YajC. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273367  Cd Length: 55  Bit Score: 35.65  E-value: 9.71e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 7268233    114 EFLSGVAEEVKEIEWPAFQKVLGTTGVVLGVIAGSSVVLLTVNFLL 159
Cdd:TIGR00964   3 KFFKEVKAELKKVVWPSRKELITYTIVVIVFVLFFSLFLFGIDYVF 48
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 114-162 1.14e-03

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 35.48  E-value: 1.14e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 7268233    114 EFLSGVAEEVKEIEWPAFQKVLGTTGVVLGVIAGSSVVLLTVNFLLAEL 162
Cdd:pfam00584   2 KFFKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVDLGFSIL 50
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 45-135 1.65e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 38.06  E-value: 1.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7268233     45 LRKSACFVAKAIE-QRRDTAGSESESEATPSPAEESGSGEDKEVEISAIGAEIKAAMEQRKTAEE-EKGKNEFLSGVAEE 122
Cdd:pfam05262 232 AQQKADFAQDNADkQRDEVRQKQQEAKNLPKPADTSSPKEDKQVAENQKREIEKAQIEIKKNDEEaLKAKDHKAFDLKQE 311

                          90
                  ....*....|...
gi 7268233    123 VKEIEWPAFQKVL 135
Cdd:pfam05262 312 SKASEKEAEDKEL 324
PTZ00121 PTZ00121
MAEBL; Provisional
 30-127 2.50e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 37.81  E-value: 2.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7268233     30 VFPVYTEIRTMTTSNLRKSACFVAKAIEQRRDTAGSESESEATPSPAEESGSGED--KEVEISAIGA---------EIKA 98
Cdd:PTZ00121 1597 VMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEElkKAEEENKIKAaeeakkaeeDKKK 1676

                          90       100
                  ....*....|....*....|....*....
gi 7268233     99 AMEQRKTAEEEKGKNEFLSGVAEEVKEIE 127
Cdd:PTZ00121 1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAE 1705
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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