|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09259 |
PRK09259 |
putative oxalyl-CoA decarboxylase; Validated |
1-572 |
0e+00 |
|
putative oxalyl-CoA decarboxylase; Validated
Pssm-ID: 236433 [Multi-domain] Cd Length: 569 Bit Score: 637.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 1 MADKSETTppsiDGNVLVAKSLSHLGVTHMFGVVGIPVTSLASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLT 80
Cdd:PRK09259 3 MSDQLQLT----DGFHLVIDALKLNGIDTIYGVVGIPITDLARLAQAEGIRYIGFRHEQSAGNAAAAAGFLTQKPGVCLT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 81 VSGPGCVHGLAGLSNAWVNTWPMVMISGSCDQR--DVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVS 158
Cdd:PRK09259 79 VSAPGFLNGLTALANATTNCFPMIMISGSSEREivDLQQGDYEELDQLNAAKPFCKAAFRVNRAEDIGIGVARAIRTAVS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 159 GRPGGCYLDIPTDVLRQKISESEADK-LVDEVERSRKEEPIRGSlrseIESAVSLLRKAERPLIVFGKGAAYSRAEDELK 237
Cdd:PRK09259 159 GRPGGVYLDLPAKVLAQTMDADEALTsLVKVVDPAPAQLPAPEA----VDRALDLLKKAKRPLIILGKGAAYAQADEQIR 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 238 KLVEITGIPFLPTPMGKGLLPDTHEFSATAARSLAIGKCDVALVVGARLNWLLHFGESPKWDKDVKFILVDVSEEEIELR 317
Cdd:PRK09259 235 EFVEKTGIPFLPMSMAKGLLPDTHPQSAAAARSLALANADVVLLVGARLNWLLSHGKGKTWGADKKFIQIDIEPQEIDSN 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 318 KP-HLGIVGDAKTVIGLLNREIKDDPFclGKSNSWVESISKKAKENGEKMEIQLAKDVVPFNFLTPMRIIRDAIlaVEGP 396
Cdd:PRK09259 315 RPiAAPVVGDIGSVMQALLAGLKQNTF--KAPAEWLDALAERKEKNAAKMAEKLSTDTQPMNFYNALGAIRDVL--KENP 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 397 SPVVVSEGANTMDVGRSVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASpDRLVVAVEGDSGFGFSAMEVETLVRYNLA 476
Cdd:PRK09259 391 DIYLVNEGANTLDLARNIIDMYKPRHRLDCGTWGVMGIGMGYAIAAAVET-GKPVVAIEGDSAFGFSGMEVETICRYNLP 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 477 VVIIVFNNGGVYGGDrrgpeEISGPHKEDPAPTSFVPNAGYHKLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNVI 556
Cdd:PRK09259 470 VTVVIFNNGGIYRGD-----DVNLSGAGDPSPTVLVHHARYDKMMEAFGGVGYNVTTPDELRHALTEAIASGKPTLINVV 544
|
570
....*....|....*.
gi 9755761 557 IDPFAGAESGRLQHKN 572
Cdd:PRK09259 545 IDPAAGTESGHITNLN 560
|
|
| IlvB |
COG0028 |
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino ... |
17-569 |
1.04e-144 |
|
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439799 [Multi-domain] Cd Length: 548 Bit Score: 428.81 E-value: 1.04e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 17 LVAKSLSHLGVTHMFGVVGIPVT----SLASRAmalGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAG 92
Cdd:COG0028 8 ALVEALEAEGVETVFGVPGGAILplydALRRQS---GIRHILVRHEQGAAFMADGYARATGKPGVCLVTSGPGATNLVTG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 93 LSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPTDV 172
Cdd:COG0028 85 LADAYMDSVPVLAITGQVPTSLIGRGAFQEVDQVGLFRPITKWSYLVTDPEDLPEVLRRAFRIATSGRPGPVVLDIPKDV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 173 LRQKISESEAdklvdEVERSRKEEPIRGSlRSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPFLPTPM 252
Cdd:COG0028 165 QAAEAEEEPA-----PPELRGYRPRPAPD-PEAIEEAAELLAAAKRPVILAGGGARRAGAAEELRALAERLGAPVVTTLM 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 253 GKGLLPDTHEFSA-------TAARSLAIGKCDVALVVGARLNWLLHFGESPkWDKDVKFILVDVSEEEIELRKP-HLGIV 324
Cdd:COG0028 239 GKGAFPEDHPLYLgmlgmhgTPAANEALAEADLVLAVGARFDDRVTGNWDE-FAPDAKIIHIDIDPAEIGKNYPvDLPIV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 325 GDAKTVIGLLNREIKDDPfclGKSNSWVESIskkaKENGEKMEIQLAKDVVPfnfLTPMRIIRdAILAVEGPSPVVVSEG 404
Cdd:COG0028 318 GDAKAVLAALLEALEPRA---DDRAAWLARI----AAWRAEYLAAYAADDGP---IKPQRVIA-ALREALPDDAIVVTDV 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 405 ANTMDVGRSVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVIIVFNN 484
Cdd:COG0028 387 GQHQMWAARYLRFRRPRRFLTSGGLGTMGYGLPAAIGAKLARPDRPVVAITGDGGFQMNLQELATAVRYGLPVKVVVLNN 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 485 GGvYGGDRRGPEEISGphkEDPAPTSFvPNAGYHKLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNVIIDPFAGAE 564
Cdd:COG0028 467 GG-LGMVRQWQELFYG---GRYSGTDL-PNPDFAKLAEAFGAKGERVETPEELEAALEEALASDGPALIDVRVDPEENPP 541
|
....*
gi 9755761 565 SGRLQ 569
Cdd:COG0028 542 GATLD 546
|
|
| PRK05858 |
PRK05858 |
acetolactate synthase; |
8-559 |
3.81e-88 |
|
acetolactate synthase;
Pssm-ID: 235629 [Multi-domain] Cd Length: 542 Bit Score: 282.77 E-value: 3.81e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 8 TPPSIDGNVLVAKSLSHLGVTHMFGVVGIPVTSLASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCV 87
Cdd:PRK05858 1 PAQTGHAGRLAARRLKAHGVDTMFTLSGGHLFPLYDGAREEGIRLIDVRHEQTAAFAAEAWAKLTRVPGVAVLTAGPGVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 88 HGLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLD 167
Cdd:PRK05858 81 NGMSAMAAAQFNQSPLVVLGGRAPALRWGMGSLQEIDHVPFVAPVTKFAATAQSAENAGRLVDQALQAAVTPHRGPVFVD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 168 IPTDVLrqkISESEADKLVDEVERSRKEEPIRGslrSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPF 247
Cdd:PRK05858 161 FPMDHA---FSMADDDGRPGALTELPAGPTPDP---DALARAAGLLAEAQRPVIMAGTDVWWGHAEAALLRLAEELGIPV 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 248 LPTPMGKGLLPDTHEFSATAARSLAIGKCDVALVVGARLNWLLHFGEspkWDKDVKFILVDVSEEEIEL-RKPHLGIVGD 326
Cdd:PRK05858 235 LMNGMGRGVVPADHPLAFSRARGKALGEADVVLVVGVPMDFRLGFGV---FGGTAQLVHVDDAPPQRAHhRPVAAGLYGD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 327 AKTVIGLLnREIKDDPfclGKSNSWVESISKKAKENGEKMEIQLAKDVVPfnfLTPMRIIRDaILAVEGPSPVVVSEGAN 406
Cdd:PRK05858 312 LSAILSAL-AGAGGDR---TDHQGWIEELRTAETAARARDAAELADDRDP---IHPMRVYGE-LAPLLDRDAIVIGDGGD 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 407 TMDVGRSVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVIIVFNNgG 486
Cdd:PRK05858 384 FVSYAGRYIDPYRPGCWLDPGPFGCLGTGPGYALAARLARPSRQVVLLQGDGAFGFSLMDVDTLVRHNLPVVSVIGNN-G 462
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 9755761 487 VYGGDRRGPEEISGphkEDPApTSFVPNAGYHKLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNVIIDP 559
Cdd:PRK05858 463 IWGLEKHPMEALYG---YDVA-ADLRPGTRYDEVVRALGGHGELVTVPAELGPALERAFASGVPYLVNVLTDP 531
|
|
| TPP_BZL_OCoD_HPCL |
cd02004 |
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of ... |
379-558 |
7.42e-81 |
|
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL cleaves the acyloin linkage of benzoin producing 2 molecules of benzaldehyde and enabling the Pseudomonas to grow on benzoin as the sole carbon and energy source. OCoD has a role in the detoxification of oxalate, catalyzing the decarboxylation of oxalyl-CoA to formate. 2-HPCL is a peroxisomal enzyme which plays a role in the alpha-oxidation of 3-methyl-branched fatty acids, catalyzing the cleavage of 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. All these enzymes depend on Mg2+ and TPP for activity.
Pssm-ID: 238962 [Multi-domain] Cd Length: 172 Bit Score: 250.91 E-value: 7.42e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 379 FLTPMRIIRDAILAvegpSPVVVSEGANTMDVGRSVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDS 458
Cdd:cd02004 1 PYRVLHELQEALPD----DAIIVSDGGNTMDWARYILRPRKPRHRLDAGTFGTLGVGLGYAIAAALARPDKRVVLVEGDG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 459 GFGFSAMEVETLVRYNLAVVIIVFNNGGVYGGDRRGPEEISGphkeDPAPTSFVPNAGYHKLIEAFGGKGYIVETPDELK 538
Cdd:cd02004 77 AFGFSGMELETAVRYNLPIVVVVGNNGGWYQGLDGQQLSYGL----GLPVTTLLPDTRYDLVAEAFGGKGELVTTPEELK 152
|
170 180
....*....|....*....|
gi 9755761 539 SALAESFAARKPAVVNVIID 558
Cdd:cd02004 153 PALKRALASGKPALINVIID 172
|
|
| acolac_lg |
TIGR00118 |
acetolactate synthase, large subunit, biosynthetic type; Two groups of proteins form ... |
14-558 |
1.28e-76 |
|
acetolactate synthase, large subunit, biosynthetic type; Two groups of proteins form acetolactate from two molecules of pyruvate. The type of acetolactate synthase described in this model also catalyzes the formation of acetohydroxybutyrate from pyruvate and 2-oxobutyrate, an early step in the branched chain amino acid biosynthesis; it is therefore also termed acetohydroxyacid synthase. In bacteria, this catalytic chain is associated with a smaller regulatory chain in an alpha2/beta2 heterotetramer. Acetolactate synthase is a thiamine pyrophosphate enzyme. In this type, FAD and Mg++ are also found. Several isozymes of this enzyme are found in E. coli K12, one of which contains a frameshift in the large subunit gene and is not expressed. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 272915 [Multi-domain] Cd Length: 558 Bit Score: 252.72 E-value: 1.28e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 14 GNVLVAKSLSHLGVTHMFGVVGIPVTSLASRAMAL-GIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAG 92
Cdd:TIGR00118 3 GAEAIIESLKDEGVKTVFGYPGGAILPIYDALYNDsGIEHILVRHEQGAAHAADGYARASGKVGVVLVTSGPGATNLVTG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 93 LSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPTDV 172
Cdd:TIGR00118 83 IATAYMDSIPMVVFTGQVPTSLIGSDAFQEADILGITMPITKHSFQVKSAEDIPRIIKEAFHIATTGRPGPVLVDLPKDV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 173 LRQKIsESEADKLVDEVERSRKEEPIRGslrsEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPFLPTPM 252
Cdd:TIGR00118 163 TTAEI-EYPYPEKVNLPGYRPTVKGHPL----QIKKAAELINLAKKPVILVGGGVIIAGASEELKELAERIQIPVTTTLM 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 253 GKGLLPDTHEFS-------ATAARSLAIGKCDVALVVGARlnwllhF-----GESPKWDKDVKFILVDVSEEEI-ELRKP 319
Cdd:TIGR00118 238 GLGSFPEDHPLSlgmlgmhGTKTANLAVHECDLIIAVGAR------FddrvtGNLAKFAPNAKIIHIDIDPAEIgKNVRV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 320 HLGIVGDAKTVIG-LLNREIKDDPFclgKSNSWVESISKKAKENGEKMEiqlaKDVVPFNfltPMRIIRDAILAVEGPSP 398
Cdd:TIGR00118 312 DIPIVGDARNVLEeLLKKLFELKER---KESAWLEQINKWKKEYPLKMD----YTEEGIK---PQQVIEELSRVTKDEAI 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 399 VVVSEGANTMDVGRsVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVV 478
Cdd:TIGR00118 382 VTTDVGQHQMWAAQ-FYPFRKPRRFITSGGLGTMGFGLPAAIGAKVAKPESTVICITGDGSFQMNLQELSTAVQYDIPVK 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 479 IIVFNNGgvYGGDRRGPEEI--SGPHKEdpapTSFVPNAGYHKLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNVI 556
Cdd:TIGR00118 461 ILILNNR--YLGMVRQWQELfyEERYSH----THMGSLPDFVKLAEAYGIKGIRIEKPEELDEKLKEALSSNEPVLLDVV 534
|
..
gi 9755761 557 ID 558
Cdd:TIGR00118 535 VD 536
|
|
| PRK06276 |
PRK06276 |
acetolactate synthase large subunit; |
20-559 |
2.41e-76 |
|
acetolactate synthase large subunit;
Pssm-ID: 235766 [Multi-domain] Cd Length: 586 Bit Score: 252.75 E-value: 2.41e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 20 KSLSHLGVTHMFGVVGIPVTSLASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGLSNAWVN 99
Cdd:PRK06276 9 KALEAEGVKIIFGYPGGALLPFYDALYDSDLIHILTRHEQAAAHAADGYARASGKVGVCVATSGPGATNLVTGIATAYAD 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 100 TWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPTDVLRQKIsE 179
Cdd:PRK06276 89 SSPVIALTGQVPTKLIGNDAFQEIDALGIFMPITKHNFQIKKPEEIPEIFRAAFEIAKTGRPGPVHIDLPKDVQEGEL-D 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 180 SEADKLVDEVERSRKEEPIRGSLRsEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPFLPTPMGKGLLPD 259
Cdd:PRK06276 168 LEKYPIPAKIDLPGYKPTTFGHPL-QIKKAAELIAEAERPVILAGGGVIISGASEELIELSELVKIPVCTTLMGKGAFPE 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 260 THEFS-------ATAARSLAIGKCDVALVVGARLNWLLHfGESPKWDKDVKFILVDVSEEEIELRKP-HLGIVGDAKTVI 331
Cdd:PRK06276 247 DHPLAlgmvgmhGTKAANYSVTESDVLIAIGCRFSDRTT-GDISSFAPNAKIIHIDIDPAEIGKNVRvDVPIVGDAKNVL 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 332 -----GLLNREIKDDpfclgksNSWVESISKKAKENGEKMEIqlakDVVPfnfLTPMRIIRDAILAVEGPSPvvVSEGAN 406
Cdd:PRK06276 326 rdllaELMKKEIKNK-------SEWLERVKKLKKESIPRMDF----DDKP---IKPQRVIKELMEVLREIDP--SKNTII 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 407 TMDVGRS------VLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVII 480
Cdd:PRK06276 390 TTDVGQNqmwmahFFKTSAPRSFISSGGLGTMGFGFPAAIGAKVAKPDANVIAITGDGGFLMNSQELATIAEYDIPVVIC 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 481 VFNN---GGVYGGDRRGPEEISGPHKEDPAPtSFVpnagyhKLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNVII 557
Cdd:PRK06276 470 IFDNrtlGMVYQWQNLYYGKRQSEVHLGETP-DFV------KLAESYGVKADRVEKPDEIKEALKEAIKSGEPYLLDIII 542
|
..
gi 9755761 558 DP 559
Cdd:PRK06276 543 DP 544
|
|
| PRK08266 |
PRK08266 |
hypothetical protein; Provisional |
14-555 |
1.06e-74 |
|
hypothetical protein; Provisional
Pssm-ID: 181337 [Multi-domain] Cd Length: 542 Bit Score: 247.23 E-value: 1.06e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 14 GNVLVAKSLSHlGVTHMFGVVGIPVTSL--ASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLA 91
Cdd:PRK08266 7 GEAIVAGLVAH-GVDTVFGLPGAQLYWLfdALYKAGDRIRVIHTRHEQAAGYMAFGYARSTGRPGVCSVVPGPGVLNAGA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 92 GLSNAWVNTWPMVMISGS--CDQRDVGRGDFQEL-DQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDI 168
Cdd:PRK08266 86 ALLTAYGCNSPVLCLTGQipSALIGKGRGHLHEMpDQLATLRSFTKWAERIEHPSEAPALVAEAFQQMLSGRPRPVALEM 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 169 PTDVLRQKISESEADKLvdeversrkeEPIRGSLRSE--IESAVSLLRKAERPLIVFGKGAAysRAEDELKKLVEITGIP 246
Cdd:PRK08266 166 PWDVFGQRAPVAAAPPL----------RPAPPPAPDPdaIAAAAALIAAAKNPMIFVGGGAA--GAGEEIRELAEMLQAP 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 247 FLPTPMGKGLLPDTHEFSAT--AARSLaIGKCDVALVVGARLnwLLHFGESPKWDKDVKFILVDVSEEEIELRKPHLGIV 324
Cdd:PRK08266 234 VVAFRSGRGIVSDRHPLGLNfaAAYEL-WPQTDVVIGIGSRL--ELPTFRWPWRPDGLKVIRIDIDPTEMRRLKPDVAIV 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 325 GDAKT-VIGLLNReikddpfcLGKSNSWVESISKKAKENGEKMEIQLAkDVVPfnFLTPMRIIRDAiLAVEGpspVVVSE 403
Cdd:PRK08266 311 ADAKAgTAALLDA--------LSKAGSKRPSRRAELRELKAAARQRIQ-AVQP--QASYLRAIREA-LPDDG---IFVDE 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 404 GANTMDVGRSVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVIIVFN 483
Cdd:PRK08266 376 LSQVGFASWFAFPVYAPRTFVTCGYQGTLGYGFPTALGAKVANPDRPVVSITGDGGFMFGVQELATAVQHNIGVVTVVFN 455
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 9755761 484 NGGvYGGDRRGPEEISGPHkedpAPTSFVPNAGYHKLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNV 555
Cdd:PRK08266 456 NNA-YGNVRRDQKRRFGGR----VVASDLVNPDFVKLAESFGVAAFRVDSPEELRAALEAALAHGGPVLIEV 522
|
|
| PRK07525 |
PRK07525 |
sulfoacetaldehyde acetyltransferase; Validated |
16-560 |
7.65e-74 |
|
sulfoacetaldehyde acetyltransferase; Validated
Pssm-ID: 236042 [Multi-domain] Cd Length: 588 Bit Score: 246.45 E-value: 7.65e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 16 VLVAKslshlGVTHMFGVVG---IPVTSLASRAmalGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAG 92
Cdd:PRK07525 15 TLQAH-----GITHAFGIIGsafMDASDLFPPA---GIRFIDVAHEQNAGHMADGYTRVTGRMGMVIGQNGPGITNFVTA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 93 LSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRpGGCYLDIPTDV 172
Cdd:PRK07525 87 VATAYWAHTPVVLVTPQAGTKTIGQGGFQEAEQMPMFEDMTKYQEEVRDPSRMAEVLNRVFDKAKRES-GPAQINIPRDY 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 173 LRQKISeseadklVDEVERSRKEEPIRGslRSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPFLPTPM 252
Cdd:PRK07525 166 FYGVID-------VEIPQPVRLERGAGG--EQSLAEAAELLSEAKFPVILSGAGVVLSDAIEECKALAERLDAPVACGYL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 253 GKGLLPDTHEFSA--------TAARSLaIGKCDVALVVGARLNwllHFGESPK-----WDKDVKFILVDVSEEEIELRKP 319
Cdd:PRK07525 237 HNDAFPGSHPLWVgplgyngsKAAMEL-IAKADVVLALGTRLN---PFGTLPQygidyWPKDAKIIQVDINPDRIGLTKK 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 320 -HLGIVGDAKTV-IGLLNReIKDDPFCLGKS-----------NSWVESISKKAKENGEKME--IQLAKDVVPfNFLTPMR 384
Cdd:PRK07525 313 vSVGICGDAKAVaRELLAR-LAERLAGDAGReerkaliaaekSAWEQELSSWDHEDDDPGTdwNEEARARKP-DYMHPRQ 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 385 IIRdAILAVEGPSPVVVSEGANTMDVGRSVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSA 464
Cdd:PRK07525 391 ALR-EIQKALPEDAIVSTDIGNNCSIANSYLRFEKGRKYLAPGSFGNCGYAFPAIIGAKIACPDRPVVGFAGDGAWGISM 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 465 MEVETLVRYNLAVVIIVFNNGGvYGGDRRgpeeisgpHKEDPAPTSFV-----PNAGYHKLIEAFGGKGYIVETPDELKS 539
Cdd:PRK07525 470 NEVMTAVRHNWPVTAVVFRNYQ-WGAEKK--------NQVDFYNNRFVgteldNNVSYAGIAEAMGAEGVVVDTQEELGP 540
|
570 580
....*....|....*....|....*....
gi 9755761 540 ALAESFAAR---KPAVVNVII-----DPF 560
Cdd:PRK07525 541 ALKRAIDAQnegKTTVIEIMCnqelgEPF 569
|
|
| sulphoacet_xsc |
TIGR03457 |
sulfoacetaldehyde acetyltransferase; Members of this protein family are sulfoacetaldehyde ... |
6-560 |
1.35e-69 |
|
sulfoacetaldehyde acetyltransferase; Members of this protein family are sulfoacetaldehyde acetyltransferase, an enzyme of taurine utilization. Taurine, or 2-aminoethanesulfonate, can be used by bacteria as a source of carbon, nitrogen, and sulfur. [Central intermediary metabolism, Other]
Pssm-ID: 132497 [Multi-domain] Cd Length: 579 Bit Score: 234.76 E-value: 1.35e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 6 ETTPPSIDGNVLVAKslshlGVTHMFGVVG---IPVTSLASRAmalGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVS 82
Cdd:TIGR03457 1 KMTPSEAFVEVLVAN-----GVTHAFGIMGsafMDAMDLFPPA---GIRFIPVVHEQGAGHMADGFARVTGRMSMVIGQN 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 83 GPGCVHGLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRpG 162
Cdd:TIGR03457 73 GPGVTNCVTAIAAAYWAHTPVVIVTPEAGTKTIGLGGFQEADQLPMFQEFTKYQGHVRHPSRMAEVLNRCFERAWREM-G 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 163 GCYLDIPTDVLRQKISEseadklvdEVER-SRKEEPIRGSlrSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVE 241
Cdd:TIGR03457 152 PAQLNIPRDYFYGEIDV--------EIPRpVRLDRGAGGA--TSLAQAARLLAEAKFPVIISGGGVVMGDAVEECKALAE 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 242 ITGIPFLPTPMGKGLLPDTHEFS--------ATAARSLaIGKCDVALVVGARLNwllHFGESPK-----WDKDVKFILVD 308
Cdd:TIGR03457 222 RLGAPVVNSYLHNDSFPASHPLWvgplgyqgSKAAMKL-ISDADVVLALGTRLG---PFGTLPQygidyWPKNAKIIQVD 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 309 VSEEEIELRKP-HLGIVGDAKTVIGLLNREIKDDPFCLGKS----------NSWVESISKKAKENGE-KMEIQLAKDVVP 376
Cdd:TIGR03457 298 ANAKMIGLVKKvTVGICGDAKAAAAEILQRLAGKAGDANRAerkakiqaerSAWEQELSEMTHERDPfSLDMIVEQRQEE 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 377 FNFLTPMRIIRDaiLAVEGPSPVVVSEG-ANTMDVGRSVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVE 455
Cdd:TIGR03457 378 GNWLHPRQVLRE--LEKAMPEDAIVSTDiGNINSVANSYLRFEKPRKFLAPMSFGNCGYAFPTIIGAKIAAPDRPVVAYA 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 456 GDSGFGFSAMEVETLVRYNLAVVIIVFNNGGvYGGDRRGPEEISGPH---KEDPAPTSFVPNAgyhkliEAFGGKGYIVE 532
Cdd:TIGR03457 456 GDGAWGMSMNEIMTAVRHDIPVTAVVFRNRQ-WGAEKKNQVDFYNNRfvgTELESELSFAGIA------DAMGAKGVVVD 528
|
570 580 590
....*....|....*....|....*....|....*.
gi 9755761 533 TPDELKSALAESFAAR---KPAVVNVII-----DPF 560
Cdd:TIGR03457 529 KPEDVGPALKKAIAAQaegKTTVIEIVCtrelgDPF 564
|
|
| PRK08322 |
PRK08322 |
acetolactate synthase large subunit; |
17-558 |
1.81e-68 |
|
acetolactate synthase large subunit;
Pssm-ID: 236239 [Multi-domain] Cd Length: 547 Bit Score: 230.87 E-value: 1.81e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 17 LVAKSLSHLGVTHMFGvvgIP-------VTSLASRamalGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHG 89
Cdd:PRK08322 6 LFVKCLENEGVEYIFG---IPgeenldlLEALRDS----SIKLILTRHEQGAAFMAATYGRLTGKAGVCLSTLGPGATNL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 90 LAGLSNAWVNTWPMVMISGscdQRDVGR---GDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYL 166
Cdd:PRK08322 79 VTGVAYAQLGGMPMVAITG---QKPIKRskqGSFQIVDVVAMMAPLTKWTRQIVSPDNIPEVVREAFRLAEEERPGAVHL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 167 DIPTDvlrqkISESEADKLVDEVERSRKEEPirgSLRSeIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIP 246
Cdd:PRK08322 156 ELPED-----IAAEETDGKPLPRSYSRRPYA---SPKA-IERAAEAIQAAKNPLILIGAGANRKTASKALTEFVDKTGIP 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 247 FLPTPMGKGLLPDTHEFSA-TAARS------LAIGKCDVALVVGARLNwllhfgESP--KW--DKDVKFILVDVSEEEIE 315
Cdd:PRK08322 227 FFTTQMGKGVIPETHPLSLgTAGLSqgdyvhCAIEHADLIINVGHDVI------EKPpfFMnpNGDKKVIHINFLPAEVD 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 316 -LRKPHLGIVGD-AKTVIGLLNReikddpfcLGKSNSWVESISKKAKENgekMEIQLAK----DVVPfnfLTPMRIIRDa 389
Cdd:PRK08322 301 pVYFPQVEVVGDiANSLWQLKER--------LADQPHWDFPRFLKIREA---IEAHLEEgaddDRFP---MKPQRIVAD- 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 390 ILAVEGPSPVVVSE-GANTMDVGRSVLVQkEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVE 468
Cdd:PRK08322 366 LRKVMPDDDIVILDnGAYKIWFARNYRAY-EPNTCLLDNALATMGAGLPSAIAAKLVHPDRKVLAVCGDGGFMMNSQELE 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 469 TLVRYNLAVVIIVFNNGGvYGGDRRGPEEISGPHkedpaptSFVP--NAGYHKLIEAFGGKGYIVETPDELKSALAESFA 546
Cdd:PRK08322 445 TAVRLGLPLVVLILNDNA-YGMIRWKQENMGFED-------FGLDfgNPDFVKYAESYGAKGYRVESADDLLPTLEEALA 516
|
570
....*....|..
gi 9755761 547 ARKPAVVNVIID 558
Cdd:PRK08322 517 QPGVHVIDCPVD 528
|
|
| PRK06048 |
PRK06048 |
acetolactate synthase large subunit; |
20-558 |
3.10e-68 |
|
acetolactate synthase large subunit;
Pssm-ID: 180368 [Multi-domain] Cd Length: 561 Bit Score: 230.82 E-value: 3.10e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 20 KSLSHLGVTHMFGVVGIPVTSLASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGLSNAWVN 99
Cdd:PRK06048 16 KCLEKEGVEVIFGYPGGAIIPVYDELYDSDLRHILVRHEQAAAHAADGYARATGKVGVCVATSGPGATNLVTGIATAYMD 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 100 TWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPTDVLRQKISE 179
Cdd:PRK06048 96 SVPIVALTGQVPRSMIGNDAFQEADITGITMPITKHNYLVQDAKDLPRIIKEAFHIASTGRPGPVLIDLPKDVTTAEIDF 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 180 SEADKlvdeVERSRKEEPIRGSLRsEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPFLPTPMGKGLLPD 259
Cdd:PRK06048 176 DYPDK----VELRGYKPTYKGNPQ-QIKRAAELIMKAERPIIYAGGGVISSNASEELVELAETIPAPVTTTLMGIGAIPT 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 260 THEFS-------ATAARSLAIGKCDVALVVGARLNWLLHfGESPKWDKDVKFILVDVSEEEIELR-KPHLGIVGDAKTVI 331
Cdd:PRK06048 251 EHPLSlgmlgmhGTKYANYAIQESDLIIAVGARFDDRVT-GKLASFAPNAKIIHIDIDPAEISKNvKVDVPIVGDAKQVL 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 332 GLLNREIKDDPFC--LGKSNSWVESISKKAKENGEKMEIQLAKDVVpfnfltpMRIIRDAIlavegpspVVVSEGANTMD 409
Cdd:PRK06048 330 KSLIKYVQYCDRKewLDKINQWKKEYPLKYKEREDVIKPQYVIEQI-------YELCPDAI--------IVTEVGQHQMW 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 410 VGRSVLVqKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVIIVFNNGgvYG 489
Cdd:PRK06048 395 AAQYFKY-KYPRTFITSGGLGTMGYGFPAAIGAKVGKPDKTVIDIAGDGSFQMNSQELATAVQNDIPVIVAILNNG--YL 471
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 9755761 490 GDRRGPEEISgpHKEDPAPTSFVPNAGYHKLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNVIID 558
Cdd:PRK06048 472 GMVRQWQELF--YDKRYSHTCIKGSVDFVKLAEAYGALGLRVEKPSEVRPAIEEAVASDRPVVIDFIVE 538
|
|
| PRK08611 |
PRK08611 |
pyruvate oxidase; Provisional |
10-559 |
6.86e-66 |
|
pyruvate oxidase; Provisional
Pssm-ID: 181502 [Multi-domain] Cd Length: 576 Bit Score: 224.88 E-value: 6.86e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 10 PSIDGNVLVAKSLSHLGVTHMFGVVGIPVTSL--ASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCV 87
Cdd:PRK08611 2 AKIKAGEALVKLLQDWGIDHVYGIPGDSIDAVvdALRKEQDKIKFIQVRHEEVAALAAAAYAKLTGKIGVCLSIGGPGAI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 88 HGLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQEL---DQIEAVKAFSKLSEKAKDVreiPDCVSRVLDRAVSGRpGGC 164
Cdd:PRK08611 82 HLLNGLYDAKMDHVPVLALAGQVTSDLLGTDFFQEVnleKMFEDVAVYNHQIMSAENL---PEIVNQAIRTAYEKK-GVA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 165 YLDIPTDVLRQKISeseaDKLVDEVERSRKEEPIrgSLRSEIESAVSLLRKAERPLIVFGKGAAYSRaeDELKKLVEITG 244
Cdd:PRK08611 158 VLTIPDDLPAQKIK----DTTNKTVDTFRPTVPS--PKPKDIKKAAKLINKAKKPVILAGLGAKHAK--EELLAFAEKAK 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 245 IPFLPTPMGKGLLPDTHEFS-------ATAARSLAIGKCDVALVVGArlnwllHFGESPKWDKDVKFILVDVSEEEIELR 317
Cdd:PRK08611 230 IPIIHTLPAKGIIPDDHPYSlgnlgkiGTKPAYEAMQEADLLIMVGT------NYPYVDYLPKKAKAIQIDTDPANIGKR 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 318 KP-HLGIVGDAKTVIGLLNREIK---DDPF---CLGKSNSWvesiskkakenGEKMEIQLAKDVVPfnfLTPMRIIR--- 387
Cdd:PRK08611 304 YPvNVGLVGDAKKALHQLTENIKhveDRRFleaCQENMAKW-----------WKWMEEDENNASTP---IKPERVMAaiq 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 388 -----DAILAVegpspvvvsegantmDVGRSVL-----VQKEPRTRLDAGTW-GTMGVGLGYCIAAAVASPDRLVVAVEG 456
Cdd:PRK08611 370 kiaddDAVLSV---------------DVGTVTVwsaryLNLGTNQKFIISSWlGTMGCGLPGAIAAKIAFPDRQAIAICG 434
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 457 DSGFGFSAMEVETLVRYNLAVVIIVFNNggvyggdrrgpEEISGPHKEDPAP------TSFvPNAGYHKLIEAFGGKGYI 530
Cdd:PRK08611 435 DGGFSMVMQDFVTAVKYKLPIVVVVLNN-----------QQLAFIKYEQQAAgeleyaIDL-SDMDYAKFAEACGGKGYR 502
|
570 580
....*....|....*....|....*....
gi 9755761 531 VETPDELKSALAESFAARKPAVVNVIIDP 559
Cdd:PRK08611 503 VEKAEELDPAFEEALAQDKPVIIDVYVDP 531
|
|
| PRK06456 |
PRK06456 |
acetolactate synthase large subunit; |
12-558 |
7.11e-63 |
|
acetolactate synthase large subunit;
Pssm-ID: 180569 [Multi-domain] Cd Length: 572 Bit Score: 216.63 E-value: 7.11e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 12 IDGNVLVAKSLSHLGVTHMFGVVGI---PVTSLASRAMALG-IRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCV 87
Cdd:PRK06456 2 PTGARILVDSLKREGVKVIFGIPGLsnmQIYDAFVEDLANGeLRHVLMRHEQAAAHAADGYARASGVPGVCTATSGPGTT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 88 HGLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLD 167
Cdd:PRK06456 82 NLVTGLITAYWDSSPVIAITGQVPRSVMGKMAFQEADAMGVFENVTKYVIGIKRIDEIPQWIKNAFYIATTGRPGPVVID 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 168 IPTDVLRQKISE--SEADKLVdeveRSRKEEPIRGSlRSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGI 245
Cdd:PRK06456 162 IPRDIFYEKMEEikWPEKPLV----KGYRDFPTRID-RLALKKAAEILINAERPIILVGTGVVWSNATPEVLELAELLHI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 246 PFLPTPMGKGLLPDTHE-------FSATAARSLAIGKCDVALVVGARLNWLLHFGESPKWDKDVKFILVDVSEEEIELR- 317
Cdd:PRK06456 237 PIVSTFPGKTAIPHDHPlyfgpmgYYGRAEASMAALESDAMLVVGARFSDRTFTSYDEMVETRKKFIMVNIDPTDGEKAi 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 318 KPHLGIVGDAKTVIgllnREIKDDPFCLGKSN---SWVESIsKKAKENGEKME-IQLAKDVVPFNFltpMRIIRDAIlav 393
Cdd:PRK06456 317 KVDVGIYGNAKIIL----RELIKAITELGQKRdrsAWLKRV-KEYKEYYSQFYyTEENGKLKPWKI---MKTIRQAL--- 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 394 egPSPVVVSEGANTMDVGRSVLVQK-EPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVR 472
Cdd:PRK06456 386 --PRDAIVTTGVGQHQMWAEVFWEVlEPRTFLTSSGMGTMGFGLPAAMGAKLARPDKVVVDLDGDGSFLMTGTNLATAVD 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 473 YNLAVVIIVFNNGGVyGGDRRGPEEISGphkEDPAPTSFVPNAGYHKLIEAFGGKGYIVETPDELKSALAESFAARKPAV 552
Cdd:PRK06456 464 EHIPVISVIFDNRTL-GLVRQVQDLFFG---KRIVGVDYGPSPDFVKLAEAFGALGFNVTTYEDIEKSLKSAIKEDIPAV 539
|
....*.
gi 9755761 553 VNVIID 558
Cdd:PRK06456 540 IRVPVD 545
|
|
| PRK08527 |
PRK08527 |
acetolactate synthase large subunit; |
58-560 |
2.20e-62 |
|
acetolactate synthase large subunit;
Pssm-ID: 181458 [Multi-domain] Cd Length: 563 Bit Score: 214.96 E-value: 2.20e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 58 EQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSE 137
Cdd:PRK08527 50 EQAAVHAADGYARASGKVGVAIVTSGPGFTNAVTGLATAYMDSIPLVLISGQVPNSLIGTDAFQEIDAVGISRPCVKHNY 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 138 KAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPTDVLRQkISESEADKlvdEVERSRKEEPIRGSLRsEIESAVSLLRKAE 217
Cdd:PRK08527 130 LVKSIEELPRILKEAFYIARSGRPGPVHIDIPKDVTAT-LGEFEYPK---EISLKTYKPTYKGNSR-QIKKAAEAIKEAK 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 218 RPLIVFGKGAAYSRAEDELKKLVEITGIPFLPTPMGKGLLPDTHEF-------SATAARSLAIGKCDVALVVGARLNWLL 290
Cdd:PRK08527 205 KPLFYLGGGAILSNASEEIRELVKKTGIPAVETLMARGVLRSDDPLllgmlgmHGSYAANMAMSECDLLISLGARFDDRV 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 291 HfGESPKWDKDVKFILVDVSEEEI-ELRKPHLGIVGDAKTVIGLLNREIKDDPFclGKSNSWVESISKkakengekmeiq 369
Cdd:PRK08527 285 T-GKLSEFAKHAKIIHVDIDPSSIsKIVNADYPIVGDLKNVLKEMLEELKEENP--TTYKEWREILKR------------ 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 370 lakdvvpFNFLTPMRII-RDAIL----AVEGPSPVVVSEGANTMDVGRSVL--VQ----KEPRTRLDAGTWGTMGVGLGY 438
Cdd:PRK08527 350 -------YNELHPLSYEdSDEVLkpqwVIERVGELLGDDAIISTDVGQHQMwvAQfypfNYPRQLATSGGLGTMGYGLPA 422
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 439 CIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVIIVFNNGgvYGGDRRGPEEISGPHKEDPAPTSFVPNagYH 518
Cdd:PRK08527 423 ALGAKLAVPDKVVINFTGDGSILMNIQELMTAVEYKIPVINIILNNN--FLGMVRQWQTFFYEERYSETDLSTQPD--FV 498
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 9755761 519 KLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNVIIDPF 560
Cdd:PRK08527 499 KLAESFGGIGFRVTTKEEFDKALKEALESDKVALIDVKIDRF 540
|
|
| PRK06725 |
PRK06725 |
acetolactate synthase large subunit; |
9-558 |
3.38e-62 |
|
acetolactate synthase large subunit;
Pssm-ID: 180672 [Multi-domain] Cd Length: 570 Bit Score: 214.83 E-value: 3.38e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 9 PPSIDGNVLVAKSLSHLGVTHMFGVVGIPVTSLASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVH 88
Cdd:PRK06725 12 CEEVTGAGHVIQCLKKLGVTTVFGYPGGAILPVYDALYESGLKHILTRHEQAAIHAAEGYARASGKVGVVFATSGPGATN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 89 GLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDI 168
Cdd:PRK06725 92 LVTGLADAYMDSIPLVVITGQVATPLIGKDGFQEADVVGITVPVTKHNYQVRDVNQLSRIVQEAFYIAESGRPGPVLIDI 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 169 PTDVLRQKISeSEADKLVDevERSRKEEPIRGSLR-SEIESAVSllrKAERPLIVFGKGAAYSRAEDELKKLVEITGIPF 247
Cdd:PRK06725 172 PKDVQNEKVT-SFYNEVVE--IPGYKPEPRPDSMKlREVAKAIS---KAKRPLLYIGGGVIHSGGSEELIEFARENRIPV 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 248 LPTPMGKGLLPDTHEF-------SATAARSLAIGKCDVALVVGARLNWLLHfGESPKWDKDVKFILVDVSEEEIELR-KP 319
Cdd:PRK06725 246 VSTLMGLGAYPPGDPLflgmlgmHGTYAANMAVTECDLLLALGVRFDDRVT-GKLELFSPHSKKVHIDIDPSEFHKNvAV 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 320 HLGIVGDAKTVIGLLNREikddPFCLGkSNSWVESIsKKAKEngekmEIQLAKDVVPfNFLTPMRIIRDAILAVEGPSPV 399
Cdd:PRK06725 325 EYPVVGDVKKALHMLLHM----SIHTQ-TDEWLQKV-KTWKE-----EYPLSYKQKE-SELKPQHVINLVSELTNGEAIV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 400 VVSEGANTMDVGRsVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVI 479
Cdd:PRK06725 393 TTEVGQHQMWAAH-FYKAKNPRTFLTSGGLGTMGFGFPAAIGAQLAKEEELVICIAGDASFQMNIQELQTIAENNIPVKV 471
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 9755761 480 IVFNNGgvYGGDRRGPEEIsgpHKEDPAPTSFVPNAGYHKLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNVIID 558
Cdd:PRK06725 472 FIINNK--FLGMVRQWQEM---FYENRLSESKIGSPDFVKVAEAYGVKGLRATNSTEAKQVMLEAFAHEGPVVVDFCVE 545
|
|
| PRK07418 |
PRK07418 |
acetolactate synthase large subunit; |
1-557 |
6.73e-59 |
|
acetolactate synthase large subunit;
Pssm-ID: 236014 [Multi-domain] Cd Length: 616 Bit Score: 206.82 E-value: 6.73e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 1 MADKSETTPPSIDGNVLVAKSLSHLGVTHMFGVVG---IPVTSLASRAMALG-IRFIAFHNEQSAGYAASAYGYLTGKPG 76
Cdd:PRK07418 8 IGDSTTVTPQRATGAYALMDSLKRHGVKHIFGYPGgaiLPIYDELYKAEAEGwLKHILVRHEQGAAHAADGYARATGKVG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 77 ILLTVSGPGCVHGLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRA 156
Cdd:PRK07418 88 VCFGTSGPGATNLVTGIATAQMDSVPMVVITGQVPRPAIGTDAFQETDIFGITLPIVKHSYVVRDPSDMARIVAEAFHIA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 157 VSGRPGGCYLDIPTDVlrqkiSESEADK---LVDEVERSRKEEPIRGSLRsEIESAVSLLRKAERPLIVFGKGAAYSRAE 233
Cdd:PRK07418 168 SSGRPGPVLIDIPKDV-----GQEEFDYvpvEPGSVKPPGYRPTVKGNPR-QINAALKLIEEAERPLLYVGGGAISAGAH 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 234 DELKKLVEITGIPFLPTPMGKGLLPDTHEFS-------ATAARSLAIGKCDVALVVGARlnwllhF-----GESPKWDKD 301
Cdd:PRK07418 242 AELKELAERFQIPVTTTLMGKGAFDEHHPLSvgmlgmhGTAYANFAVTECDLLIAVGAR------FddrvtGKLDEFASR 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 302 VKFILVDVSEEEI-ELRKPHLGIVGDAKTVIGLLNREIKDDPFcLGKSNSWVESIsKKAKENGEKMEIQLAKDVVPfnfl 380
Cdd:PRK07418 316 AKVIHIDIDPAEVgKNRRPDVPIVGDVRKVLVKLLERSLEPTT-PPRTQAWLERI-NRWKQDYPLVVPPYEGEIYP---- 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 381 tpmriiRDAILAVEGPSPvvvsEGANTMDVGRSVL-----VQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVE 455
Cdd:PRK07418 390 ------QEVLLAVRDLAP----DAYYTTDVGQHQMwaaqfLRNGPRRWISSAGLGTMGFGMPAAMGVKVALPDEEVICIA 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 456 GDSGFGFSAMEVETLVRYNLAVVIIVFNNG----------GVYGgdrrgpEEISGPHKEDPAPtSFVpnagyhKLIEAFG 525
Cdd:PRK07418 460 GDASFLMNIQELGTLAQYGINVKTVIINNGwqgmvrqwqeSFYG------ERYSASNMEPGMP-DFV------KLAEAFG 526
|
570 580 590
....*....|....*....|....*....|..
gi 9755761 526 GKGYIVETPDELKSALAESFAARKPAVVNVII 557
Cdd:PRK07418 527 VKGMVISERDQLKDAIAEALAHDGPVLIDVHV 558
|
|
| PRK06965 |
PRK06965 |
acetolactate synthase 3 catalytic subunit; Validated |
2-545 |
8.92e-59 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 180780 [Multi-domain] Cd Length: 587 Bit Score: 205.81 E-value: 8.92e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 2 ADKSETTPPSIDGNVLVAKSLSHLGVTHMFGVVGIPVTSLASramAL----GIRFIAFHNEQSAGYAASAYGYLTGKPGI 77
Cdd:PRK06965 11 AESLSPPAADSIGAEILMKALAAEGVEFIWGYPGGAVLYIYD---ELykqdKIQHVLVRHEQAAVHAADGYARATGKVGV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 78 LLTVSGPGCVHGLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAV 157
Cdd:PRK06965 88 ALVTSGPGVTNAVTGIATAYMDSIPMVVISGQVPTAAIGQDAFQECDTVGITRPIVKHNFLVKDVRDLAETVKKAFYIAR 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 158 SGRPGGCYLDIPTDVLRQKISESEADKLvdeveRSRKEEPIRGSLRSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELK 237
Cdd:PRK06965 168 TGRPGPVVVDIPKDVSKTPCEYEYPKSV-----EMRSYNPVTKGHSGQIRKAVSLLLSAKRPYIYTGGGVILANASRELR 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 238 KLVEITGIPFLPTPMGKGLLPDTHE-------FSATAARSLAIGKCDVALVVGARLNWLL-----HFGESPKwdkdvKFI 305
Cdd:PRK06965 243 QLADLLGYPVTNTLMGLGAYPASDKkflgmlgMHGTYEANMAMQHCDVLIAIGARFDDRVignpaHFASRPR-----KII 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 306 LVDVSEEEIELR-KPHLGIVGDAKTVIGLLNREIKD-----DPFCLGKsnsWVESISKKAKEngEKMEIQLAKDVVpfnf 379
Cdd:PRK06965 318 HIDIDPSSISKRvKVDIPIVGDVKEVLKELIEQLQTaehgpDADALAQ---WWKQIEGWRSR--DCLKYDRESEII---- 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 380 lTPMRIIRDAILAVEGPSPVvvseganTMDVGRSVL--VQ----KEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVA 453
Cdd:PRK06965 389 -KPQYVVEKLWELTDGDAFV-------CSDVGQHQMwaAQfyrfNEPRRWINSGGLGTMGVGLPYAMGIKMAHPDDDVVC 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 454 VEGDSGFGFSAMEVETLVRYNLAVVIIVFNNGgvYGGDRRGPEEISGPHKEDPAPTSFVPNagYHKLIEAFGGKGYIVET 533
Cdd:PRK06965 461 ITGEGSIQMCIQELSTCLQYDTPVKIISLNNR--YLGMVRQWQEIEYSKRYSHSYMDALPD--FVKLAEAYGHVGMRIEK 536
|
570
....*....|..
gi 9755761 534 PDELKSALAESF 545
Cdd:PRK06965 537 TSDVEPALREAL 548
|
|
| ilvB |
CHL00099 |
acetohydroxyacid synthase large subunit |
21-559 |
3.15e-57 |
|
acetohydroxyacid synthase large subunit
Pssm-ID: 214363 [Multi-domain] Cd Length: 585 Bit Score: 201.47 E-value: 3.15e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 21 SLSHLGVTHMFGVVG---IPV-TSLASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGLSNA 96
Cdd:CHL00099 19 SLVRHGVKHIFGYPGgaiLPIyDELYAWEKKGLIKHILVRHEQGAAHAADGYARSTGKVGVCFATSGPGATNLVTGIATA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 97 WVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPTDVLRQK 176
Cdd:CHL00099 99 QMDSVPLLVITGQVGRAFIGTDAFQEVDIFGITLPIVKHSYVVRDARDISRIVAEAFYIAKHGRPGPVLIDIPKDVGLEK 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 177 ISESEADKlVDEVERSRKEEPIRGSLRSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPFLPTPMGKGL 256
Cdd:CHL00099 179 FDYYPPEP-GNTIIKILGCRPIYKPTIKRIEQAAKLILQSSQPLLYVGGGAIISDAHQEITELAELYKIPVTTTLMGKGI 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 257 LPDTHEFS-------ATAARSLAIGKCDVALVVGARlnwllhFGE--SPKWDK---DVKFILVDVSEEEI-ELRKPHLGI 323
Cdd:CHL00099 258 FDEDHPLClgmlgmhGTAYANFAVSECDLLIALGAR------FDDrvTGKLDEfacNAQVIHIDIDPAEIgKNRIPQVAI 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 324 VGDAKTVIGLLNREIKDDPFCLGK--SNSWVESISKKAKEngekMEIQLAKDVvpfNFLTPMRIIRDaiLAVEGPSPVVv 401
Cdd:CHL00099 332 VGDVKKVLQELLELLKNSPNLLESeqTQAWRERINRWRKE----YPLLIPKPS---TSLSPQEVINE--ISQLAPDAYF- 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 402 seganTMDVGR-----SVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLA 476
Cdd:CHL00099 402 -----TTDVGQhqmwaAQFLKCKPRKWLSSAGLGTMGYGLPAAIGAQIAHPNELVICISGDASFQMNLQELGTIAQYNLP 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 477 VVIIVFNN---GGV-------YGgdrrgpEEISGPHKEDPAPtSFVpnagyhKLIEAFGGKGYIVETPDELKSALAESFA 546
Cdd:CHL00099 477 IKIIIINNkwqGMVrqwqqafYG------ERYSHSNMEEGAP-DFV------KLAEAYGIKGLRIKSRKDLKSSLKEALD 543
|
570
....*....|...
gi 9755761 547 ARKPAVVNVIIDP 559
Cdd:CHL00099 544 YDGPVLIDCQVIE 556
|
|
| PRK08199 |
PRK08199 |
thiamine pyrophosphate protein; Validated |
5-559 |
2.59e-56 |
|
thiamine pyrophosphate protein; Validated
Pssm-ID: 181285 [Multi-domain] Cd Length: 557 Bit Score: 198.56 E-value: 2.59e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 5 SETTPPSIDGNVLVAKSLSHLGVTHMFGVVG---IPV-TSLASRAmalGIRFIAFHNEQSAGYAASAYGYLTGKPGILLT 80
Cdd:PRK08199 1 MTSTPRARTGGQILVDALRANGVERVFCVPGesyLAVlDALHDET---DIRVIVCRQEGGAAMMAEAYGKLTGRPGICFV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 81 VSGPGCVHGLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGR 160
Cdd:PRK08199 78 TRGPGATNASIGVHTAFQDSTPMILFVGQVARDFREREAFQEIDYRRMFGPMAKWVAEIDDAARIPELVSRAFHVATSGR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 161 PGGCYLDIPTDVLRQKISESEAdklvdeversRKEEPIRGSLRSE-IESAVSLLRKAERPLIVFGKGAAYSRAEDELKKL 239
Cdd:PRK08199 158 PGPVVLALPEDVLSETAEVPDA----------PPYRRVAAAPGAAdLARLAELLARAERPLVILGGSGWTEAAVADLRAF 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 240 VEITGIPFLPTPMGKGLLPDTHE-------FSATAARSLAIGKCDVALVVGARLN-------WLLhfgESPKWDKdvKFI 305
Cdd:PRK08199 228 AERWGLPVACAFRRQDLFDNRHPnyagdlgLGINPALAARIREADLVLAVGTRLGevttqgyTLL---DIPVPRQ--TLV 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 306 LVDVSEEEI-ELRKPHLGIVGDAK-TVIGLLNREIKDDPfclgksnSWVESiskkAKENGEKMEIQLAKDVVPFNFLTP- 382
Cdd:PRK08199 303 HVHPDAEELgRVYRPDLAIVADPAaFAAALAALEPPASP-------AWAEW----TAAAHADYLAWSAPLPGPGAVQLGe 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 383 -MRIIRDAIlavegPSPVVVSEGANTMdvgrSVLVQ-----KEPRTRLdAGTWGTMGVGLGYCIAAAVASPDRLVVAVEG 456
Cdd:PRK08199 372 vMAWLRERL-----PADAIITNGAGNY----ATWLHrffrfRRYRTQL-APTSGSMGYGLPAAIAAKLLFPERTVVAFAG 441
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 457 DSGFGFSAMEVETLVRYNLAVVIIVFNNgGVYGG-----DRRGPEEISGphkedpapTSFVpNAGYHKLIEAFGGKGYIV 531
Cdd:PRK08199 442 DGCFLMNGQELATAVQYGLPIIVIVVNN-GMYGTirmhqEREYPGRVSG--------TDLT-NPDFAALARAYGGHGETV 511
|
570 580
....*....|....*....|....*...
gi 9755761 532 ETPDELKSALAESFAARKPAVVNVIIDP 559
Cdd:PRK08199 512 ERTEDFAPAFERALASGKPALIEIRIDP 539
|
|
| PRK08617 |
PRK08617 |
acetolactate synthase AlsS; |
17-558 |
6.50e-56 |
|
acetolactate synthase AlsS;
Pssm-ID: 236312 [Multi-domain] Cd Length: 552 Bit Score: 197.38 E-value: 6.50e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 17 LVAKSLSHLGVTHMFGVVGIPVTSLASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGLSNA 96
Cdd:PRK08617 10 LVVDSLINQGVKYVFGIPGAKIDRVFDALEDSGPELIVTRHEQNAAFMAAAIGRLTGKPGVVLVTSGPGVSNLATGLVTA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 97 WVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPTDVLRQK 176
Cdd:PRK08617 90 TAEGDPVVAIGGQVKRADRLKRTHQSMDNVALFRPITKYSAEVQDPDNLSEVLANAFRAAESGRPGAAFVSLPQDVVDAP 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 177 ISeSEADKLVdeversrkEEPIRGSL-RSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPFLPTPMGKG 255
Cdd:PRK08617 170 VT-SKAIAPL--------SKPKLGPAsPEDINYLAELIKNAKLPVLLLGMRASSPEVTAAIRRLLERTNLPVVETFQAAG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 256 LLPDTHE---------FSATAARSLaIGKCDVALVVG-------ARLnwllhfgespkWDK--DVKFILVDVSEEEIELR 317
Cdd:PRK08617 241 VISRELEdhffgrvglFRNQPGDEL-LKKADLVITIGydpieyePRN-----------WNSegDATIIHIDVLPAEIDNY 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 318 -KPHLGIVGDAKTVIGLLNREIKDdpfclgksnswvESISKKAKENGEKMEIQLAKDVVPFNFLT-----PMRIIRDAil 391
Cdd:PRK08617 309 yQPERELIGDIAATLDLLAEKLDG------------LSLSPQSLEILEELRAQLEELAERPARLEegavhPLRIIRAL-- 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 392 avegpSPVVVSEGANTMDVG----------RSVlvqkEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFG 461
Cdd:PRK08617 375 -----QDIVTDDTTVTVDVGshyiwmaryfRSY----EPRHLLFSNGMQTLGVALPWAIAAALVRPGKKVVSVSGDGGFL 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 462 FSAMEVETLVRYNLAVVIIVFNNGGV----------YGgdrrgpeEISGPhkeDPAPTSFVpnagyhKLIEAFGGKGYIV 531
Cdd:PRK08617 446 FSAMELETAVRLKLNIVHIIWNDGHYnmvefqeemkYG-------RSSGV---DFGPVDFV------KYAESFGAKGLRV 509
|
570 580
....*....|....*....|....*..
gi 9755761 532 ETPDELKSALAESFAARKPAVVNVIID 558
Cdd:PRK08617 510 TSPDELEPVLREALATDGPVVIDIPVD 536
|
|
| PRK06154 |
PRK06154 |
thiamine pyrophosphate-requiring protein; |
1-556 |
1.86e-55 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 235718 [Multi-domain] Cd Length: 565 Bit Score: 196.57 E-value: 1.86e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 1 MADKSETTP--------PSIDGNVLVAKSLSHLGVTHMFGvvgIPVTSLASRAMALGIRFIAFHNEQSAGYAASAYGYLT 72
Cdd:PRK06154 1 MADGTHALPnahlpaeaKTMKVAEAVAEILKEEGVELLFG---FPVNELFDAAAAAGIRPVIARTERVAVHMADGYARAT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 73 G--KPGILLTVSGPGCVHGLAGLSNAWVNTWPMVMISGSCDQR--DVgRGDFQELdqiEAVKAFSKLSEKAKDVREIPDC 148
Cdd:PRK06154 78 SgeRVGVFAVQYGPGAENAFGGVAQAYGDSVPVLFLPTGYPRGstDV-APNFESL---RNYRHITKWCEQVTLPDEVPEL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 149 VSRVLDRAVSGRPGGCYLDIPTDVLRQKISESEADKlvdevERSRKEEPIRGSlrSEIESAVSLLRKAERPLIVFGKGAA 228
Cdd:PRK06154 154 MRRAFTRLRNGRPGPVVLELPVDVLAEELDELPLDH-----RPSRRSRPGADP--VEVVEAAALLLAAERPVIYAGQGVL 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 229 YSRAEDELKKLVEITGIPFLPTPMGKGLLPDTHEFS---------ATAARSLAigKCDVALVVGARLNWLLHFGESPKwD 299
Cdd:PRK06154 227 YAQATPELKELAELLEIPVMTTLNGKSAFPEDHPLAlgsggrarpATVAHFLR--EADVLFGIGCSLTRSYYGLPMPE-G 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 300 KDVKFILVDVSEEEIELRKPHlGIVGDAKTV----IGLLNREIKDDPfclGKSNSWVESISKKAKENGEKMEIQLAKDVV 375
Cdd:PRK06154 304 KTIIHSTLDDADLNKDYPIDH-GLVGDAALVlkqmIEELRRRVGPDR---GRAQQVAAEIEAVRAAWLAKWMPKLTSDST 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 376 PfnfLTPMRIIRDAILAVEGPSPVVVSEGANTMDVGRSVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVE 455
Cdd:PRK06154 380 P---INPYRVVWELQHAVDIKTVIITHDAGSPRDQLSPFYVASRPGSYLGWGKTTQLGYGLGLAMGAKLARPDALVINLW 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 456 GDSGFGFSAMEVETLVRYNLAVVIIVFNNGGVYGGDRRGPEEiSGPHKEDPAPTSFVPNAgyhkliEAFGGKGYIVETPD 535
Cdd:PRK06154 457 GDAAFGMTGMDFETAVRERIPILTILLNNFSMGGYDKVMPVS-TTKYRATDISGDYAAIA------RALGGYGERVEDPE 529
|
570 580
....*....|....*....|....*.
gi 9755761 536 ELKSALAEsfAARK-----PAVVNVI 556
Cdd:PRK06154 530 MLVPALLR--ALRKvkegtPALLEVI 553
|
|
| PRK07524 |
PRK07524 |
5-guanidino-2-oxopentanoate decarboxylase; |
14-555 |
1.83e-54 |
|
5-guanidino-2-oxopentanoate decarboxylase;
Pssm-ID: 236041 [Multi-domain] Cd Length: 535 Bit Score: 192.88 E-value: 1.83e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 14 GNVLVaKSLSHLGVTHMFGVVGIPVTSLASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGL 93
Cdd:PRK07524 5 GEALV-RLLEAYGVETVFGIPGVHTVELYRGLAGSGIRHVTPRHEQGAGFMADGYARVSGKPGVCFIITGPGMTNIATAM 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 94 SNAWVNTWPMVMISG--SCDQRDVGRGDFQEL-DQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPT 170
Cdd:PRK07524 84 GQAYADSIPMLVISSvnRRASLGKGRGKLHELpDQRAMVAGVAAFSHTLMSAEDLPEVLARAFAVFDSARPRPVHIEIPL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 171 DVLRQKISESeadkLVDEVERSRKEEPIRGSLRseieSAVSLLRKAERPLIVFGKGAAysRAEDELKKLVEITGIPFLPT 250
Cdd:PRK07524 164 DVLAAPADHL----LPAPPTRPARPGPAPAALA----QAAERLAAARRPLILAGGGAL--AAAAALRALAERLDAPVALT 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 251 PMGKGLLPDTHEFSATAARSLA-----IGKCDVALVVGARLnwllhfGESpkwDKDVKF----------ILVDVSEEEI- 314
Cdd:PRK07524 234 INAKGLLPAGHPLLLGASQSLPavralIAEADVVLAVGTEL------GET---DYDVYFdggfplpgelIRIDIDPDQLa 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 315 ELRKPHLGIVGDAKTVIGLLNREIKDDPfclgksnswveSISKKAKENGEKMEIQLAKDVVPfNFLTPMRIIrDAILAvE 394
Cdd:PRK07524 305 RNYPPALALVGDARAALEALLARLPGQA-----------AAADWGAARVAALRQALRAEWDP-LTAAQVALL-DTILA-A 370
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 395 GPSPVVVSEGANTMDVGRSVLVQKEPRTRLDAGT-WGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRY 473
Cdd:PRK07524 371 LPDAIFVGDSTQPVYAGNLYFDADAPRRWFNASTgYGTLGYGLPAAIGAALGAPERPVVCLVGDGGLQFTLPELASAVEA 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 474 NLAVVIIVFNNGGvYGGDRRGPEE--ISgPHKEDPAPTSFVPNAgyhkliEAFGGKGYIVETPDELKSALAESFAARKPA 551
Cdd:PRK07524 451 DLPLIVLLWNNDG-YGEIRRYMVArdIE-PVGVDPYTPDFIALA------RAFGCAAERVADLEQLQAALRAAFARPGPT 522
|
....
gi 9755761 552 VVNV 555
Cdd:PRK07524 523 LIEV 526
|
|
| PRK06112 |
PRK06112 |
acetolactate synthase catalytic subunit; Validated |
17-561 |
4.26e-54 |
|
acetolactate synthase catalytic subunit; Validated
Pssm-ID: 235700 [Multi-domain] Cd Length: 578 Bit Score: 193.05 E-value: 4.26e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 17 LVAKSLSHLGVTHMFGVvGIPvTSLASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGLSNA 96
Cdd:PRK06112 19 AIARALKRHGVEQIFGQ-SLP-SALFLAAEAIGIRQIAYRTENAGGAMADGYARVSGKVAVVTAQNGPAATLLVAPLAEA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 97 WVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPTDVLRqk 176
Cdd:PRK06112 97 LKASVPIVALVQDVNRDQTDRNAFQELDHIALFQSCTKWVRRVTVAERIDDYVDQAFTAATSGRPGPVVLLLPADLLT-- 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 177 iSESEADKLVDE-------VERSRKEepirgslRSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPFLP 249
Cdd:PRK06112 175 -AAAAAPAAPRSnslghfpLDRTVPA-------PQRLAEAASLLAQAQRPVVVAGGGVHISGASAALAALQSLAGLPVAT 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 250 TPMGKGLLPDTHEFSA------TAARSLA------IGKCDVALVVGARLN------WLLhfgespkWDKDVKFILVDVSE 311
Cdd:PRK06112 247 TNMGKGAVDETHPLSLgvvgslMGPRSPGrhlrdlVREADVVLLVGTRTNqngtdsWSL-------YPEQAQYIHIDVDG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 312 EEIELRKPHLGIVGDAK-TVIGLLNR-EIKDDPFCLGKSNSWVESISKKAKENGEKMEIQLAKDVVPfnfLTPMRIIRDA 389
Cdd:PRK06112 320 EEVGRNYEALRLVGDARlTLAALTDAlRGRDLAARAGRRAALEPAIAAGREAHREDSAPVALSDASP---IRPERIMAEL 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 390 ILAVEGPSPVVVSEGANTMDVGrSVLVQKEPRTRL--DAGTWGtMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEV 467
Cdd:PRK06112 397 QAVLTGDTIVVADASYSSIWVA-NFLTARRAGMRFltPRGLAG-LGWGVPMAIGAKVARPGAPVICLVGDGGFAHVWAEL 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 468 ETLVRYNLAVVIIVFNNgGVYGGDRRGPEEISGPHkedpapTSFVPNAG--YHKLIEAFGGKGYIVETPDELKSALAESF 545
Cdd:PRK06112 475 ETARRMGVPVTIVVLNN-GILGFQKHAETVKFGTH------TDACHFAAvdHAAIARACGCDGVRVEDPAELAQALAAAM 547
|
570
....*....|....*.
gi 9755761 546 AARKPAVVNVIIDPFA 561
Cdd:PRK06112 548 AAPGPTLIEVITDPSA 563
|
|
| PRK06466 |
PRK06466 |
acetolactate synthase 3 large subunit; |
14-560 |
5.99e-53 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 180578 [Multi-domain] Cd Length: 574 Bit Score: 189.57 E-value: 5.99e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 14 GNVLVAKSLSHLGVTHMFGVVGIPVTSLASramAL----GIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHG 89
Cdd:PRK06466 6 GAEMLVRALRDEGVEYIYGYPGGAVLHIYD---ALfkqdKVEHILVRHEQAATHMADGYARATGKTGVVLVTSGPGATNA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 90 LAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIP 169
Cdd:PRK06466 83 ITGIATAYMDSIPMVVLSGQVPSTLIGEDAFQETDMVGISRPIVKHSFMVKHASEIPEIIKKAFYIAQSGRPGPVVVDIP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 170 TDVlrqkiseseadklVDEVERSRKEEPIRGSLRS----------EIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKL 239
Cdd:PRK06466 163 KDM-------------TNPAEKFEYEYPKKVKLRSyspavrghsgQIRKAVEMLLAAKRPVIYSGGGVVLGNASALLTEL 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 240 VEITGIPFLPTPMGKGLLPDTHE-------FSATAARSLAIGKCDVALVVGARLNWLLHFGESpKWDKDVKFILVDVSEE 312
Cdd:PRK06466 230 AHLLNLPVTNTLMGLGGFPGTDRqflgmlgMHGTYEANMAMHHADVILAVGARFDDRVTNGPA-KFCPNAKIIHIDIDPA 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 313 EI-ELRKPHLGIVGDAKTVIGLLNREIKDDPFCLGKS--NSWVESISKKAKENGekmeiQLAKDVVPFNFLTPMRIIRDA 389
Cdd:PRK06466 309 SIsKTIKADIPIVGPVESVLTEMLAILKEIGEKPDKEalAAWWKQIDEWRGRHG-----LFPYDKGDGGIIKPQQVVETL 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 390 ILAVEGPSPVvvseganTMDVGRSVLVQ------KEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFS 463
Cdd:PRK06466 384 YEVTNGDAYV-------TSDVGQHQMFAaqyykfNKPNRWINSGGLGTMGFGLPAAMGVKLAFPDQDVACVTGEGSIQMN 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 464 AMEVETLVRYNLAVVIIVFNNGGV----------YGGDRRGPEEISGPhkedpaptSFVpnagyhKLIEAFGGKGYIVET 533
Cdd:PRK06466 457 IQELSTCLQYGLPVKIINLNNGALgmvrqwqdmqYEGRHSHSYMESLP--------DFV------KLAEAYGHVGIRITD 522
|
570 580
....*....|....*....|....*...
gi 9755761 534 PDELKSALAESFAARKPAV-VNVIIDPF 560
Cdd:PRK06466 523 LKDLKPKLEEAFAMKDRLVfIDIYVDRS 550
|
|
| PRK08979 |
PRK08979 |
acetolactate synthase 3 large subunit; |
12-558 |
1.09e-51 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181602 [Multi-domain] Cd Length: 572 Bit Score: 186.18 E-value: 1.09e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 12 IDGNVLVAKSLSHLGVTHMFGVVGIPVTSL-ASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGL 90
Cdd:PRK08979 4 LSGASMIVRSLIDEGVKHIFGYPGGSVLDIyDALHEKSGIEHILVRHEQAAVHMADGYARATGKVGVVLVTSGPGATNTI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 91 AGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPT 170
Cdd:PRK08979 84 TGIATAYMDSIPMVVLSGQVPSNLIGNDAFQECDMIGISRPVVKHSFLVKDAEDIPEIIKKAFYIASTGRPGPVVIDLPK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 171 DVLRQKISEseaDKLVDEVERSRKEEPIRGSLRSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPFLPT 250
Cdd:PRK08979 164 DCLNPAILH---PYEYPESIKMRSYNPTTSGHKGQIKRGLQALLAAKKPVLYVGGGAIISGADKQILQLAEKLNLPVVST 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 251 PMGKGLLPDTHEFS-------ATAARSLAIGKCDVALVVGARL-----NWLlhfgesPKWDKDVKFILVDVSEEEIELR- 317
Cdd:PRK08979 241 LMGLGAFPGTHKNSlgmlgmhGRYEANMAMHNADLIFGIGVRFddrttNNL------EKYCPNATILHIDIDPSSISKTv 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 318 KPHLGIVGDAKTV----IGLLN--REIKDDpfclGKSNSWVESISKKAKENGekmeiqLAKDVVPfNFLTPMRIIRDAIL 391
Cdd:PRK08979 315 RVDIPIVGSADKVldsmLALLDesGETNDE----AAIASWWNEIEVWRSRNC------LAYDKSS-ERIKPQQVIETLYK 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 392 AVEGPSPVVVSEGANTMDVGRSVLVQKePRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLV 471
Cdd:PRK08979 384 LTNGDAYVASDVGQHQMFAALYYPFDK-PRRWINSGGLGTMGFGLPAAMGVKFAMPDETVVCVTGDGSIQMNIQELSTAL 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 472 RYNLAVVIIVFNNGgvYGGDRRGPEEI--SGPHKEdpAPTSFVPNagYHKLIEAFGGKGYIVETPDELKSALAESFAARK 549
Cdd:PRK08979 463 QYDIPVKIINLNNR--FLGMVKQWQDMiyQGRHSH--SYMDSVPD--FAKIAEAYGHVGIRISDPDELESGLEKALAMKD 536
|
570
....*....|
gi 9755761 550 PAV-VNVIID 558
Cdd:PRK08979 537 RLVfVDINVD 546
|
|
| PRK08155 |
PRK08155 |
acetolactate synthase large subunit; |
2-559 |
7.27e-51 |
|
acetolactate synthase large subunit;
Pssm-ID: 181257 [Multi-domain] Cd Length: 564 Bit Score: 183.76 E-value: 7.27e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 2 ADKSETTPPSIDGNVLVAKSLSHLGVTHmfgVVGIPVTSLASRAMALG----IRFIAFHNEQSAGYAASAYGYLTGKPGI 77
Cdd:PRK08155 3 SSGTTSTRKRFTGAELIVRLLERQGIRI---VTGIPGGAILPLYDALSqstqIRHILARHEQGAGFIAQGMARTTGKPAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 78 LLTVSGPGCVHGLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAV 157
Cdd:PRK08155 80 CMACSGPGATNLVTAIADARLDSIPLVCITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRDIEELPQVISDAFRIAQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 158 SGRPGGCYLDIPTDVLRQKIsesEADKLVDEVERSRKEEPIRgslrSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELK 237
Cdd:PRK08155 160 SGRPGPVWIDIPKDVQTAVI---ELEALPAPAEKDAAPAFDE----ESIRDAAAMINAAKRPVLYLGGGVINSGAPARAR 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 238 KLVEITGIPFLPTPMGKGLLPDTHEFS-----ATAARS--LAIGKCDVALVVGARlnwllhF-----GESPKWDKDVKFI 305
Cdd:PRK08155 233 ELAEKAQLPTTMTLMALGMLPKAHPLSlgmlgMHGARStnYILQEADLLIVLGAR------FddraiGKTEQFCPNAKII 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 306 LVDVSEEEI-ELRKPHLGIVGDAKTVIGLLNREIKDDPfclgkSNSWVESISKKAKENGekMEIQLAKDvvPfnfLTPMR 384
Cdd:PRK08155 307 HVDIDRAELgKIKQPHVAIQADVDDVLAQLLPLVEAQP-----RAEWHQLVADLQREFP--CPIPKADD--P---LSHYG 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 385 IIRDAILAVEGPSPVVVSEGANTMDVGRSVLVQKePRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSA 464
Cdd:PRK08155 375 LINAVAACVDDNAIITTDVGQHQMWTAQAYPLNR-PRQWLTSGGLGTMGFGLPAAIGAALANPERKVLCFSGDGSLMMNI 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 465 MEVETLVRYNLAVVIIVFNN---------------GGVYGGDRRGpeeisgphkedpaPTSFVpnagyhKLIEAFGGKGY 529
Cdd:PRK08155 454 QEMATAAENQLDVKIILMNNealglvhqqqslfygQRVFAATYPG-------------KINFM------QIAAGFGLETC 514
|
570 580 590
....*....|....*....|....*....|
gi 9755761 530 IVETPDELKSALAESFAARKPAVVNVIIDP 559
Cdd:PRK08155 515 DLNNEADPQAALQEAINRPGPALIHVRIDA 544
|
|
| PRK07282 |
PRK07282 |
acetolactate synthase large subunit; |
14-557 |
3.76e-50 |
|
acetolactate synthase large subunit;
Pssm-ID: 180919 [Multi-domain] Cd Length: 566 Bit Score: 181.94 E-value: 3.76e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 14 GNVLVAKSLSHLGVTHMFGVVGIPVTSLASRAMAL-GIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAG 92
Cdd:PRK07282 12 GSDLVLETLRDLGVDTIFGYPGGAVLPLYDAIYNFeGIRHILARHEQGALHEAEGYAKSTGKLGVAVVTSGPGATNAITG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 93 LSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPTDV 172
Cdd:PRK07282 92 IADAMSDSVPLLVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQIRETADIPRIITEAVHIATTGRPGPVVIDLPKDV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 173 lrqkiSESEADKLVDEVERSRKEEPIRGSLRSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPFLPTPM 252
Cdd:PRK07282 172 -----SALETDFIYDPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVILAGGGINYAEAATELNAFAERYQIPVVTTLL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 253 GKGLLPDTHEFS-------ATAARSLAIGKCDVALVVGARLNWLLhFGESPKWDKDVKFILVDVSEEEI-ELRKPHLGIV 324
Cdd:PRK07282 247 GQGTIATSHPLFlgmggmhGSYAANIAMTEADFMINIGSRFDDRL-TGNPKTFAKNAKVAHIDIDPAEIgKIIKTDIPVV 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 325 GDAKTVIGLLNREIKDDpfclGKSNSWVEsiskKAKENGEKMEIQLAKDVVpfnfLTPMRIIRDAILAVEGPSPVVVSEG 404
Cdd:PRK07282 326 GDAKKALQMLLAEPTVH----NNTEKWIE----KVTKDKNRVRSYDKKERV----VQPQAVIERIGELTNGDAIVVTDVG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 405 ANTMDVGRSVLVQKEpRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVIIVFNN 484
Cdd:PRK07282 394 QHQMWAAQYYPYQNE-RQLVTSGGLGTMGFGIPAAIGAKIANPDKEVILFVGDGGFQMTNQELAILNIYKVPIKVVMLNN 472
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 9755761 485 GGVyGGDRRGPEEIsgpHKEDPAPTSFVPNAGYHKLIEAFGGKGYIVETPDELKSALaESFAARKPAVVNVII 557
Cdd:PRK07282 473 HSL-GMVRQWQESF---YEGRTSESVFDTLPDFQLMAQAYGIKHYKFDNPETLAQDL-EVITEDVPMLIEVDI 540
|
|
| PRK07710 |
PRK07710 |
acetolactate synthase large subunit; |
5-555 |
3.43e-49 |
|
acetolactate synthase large subunit;
Pssm-ID: 236076 [Multi-domain] Cd Length: 571 Bit Score: 179.19 E-value: 3.43e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 5 SETTPPSIDGNVLVAKSLSHLGVTHMFGVVGIPVTSLASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGP 84
Cdd:PRK07710 9 SKTEEKLMTGAQMLIEALEKEGVEVIFGYPGGAVLPLYDALYDCGIPHILTRHEQGAIHAAEGYARISGKPGVVIATSGP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 85 GCVHGLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGC 164
Cdd:PRK07710 89 GATNVVTGLADAMIDSLPLVVFTGQVATSVIGSDAFQEADIMGITMPVTKHNYQVRKASDLPRIIKEAFHIATTGRPGPV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 165 YLDIPTDVLRQKiSESEADKLVDEVERSRKEEPIRGSLRSEIEsAVSllrKAERPLIVFGKGAAYSRAEDELKKLVEITG 244
Cdd:PRK07710 169 LIDIPKDMVVEE-GEFCYDVQMDLPGYQPNYEPNLLQIRKLVQ-AVS---VAKKPVILAGAGVLHAKASKELTSYAEQQE 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 245 IPFLPTPMGKGLLPDTHEF-------SATAARSLAIGKCDVALVVGARLN-----WLLHFGespkwdKDVKFILVDVSEE 312
Cdd:PRK07710 244 IPVVHTLLGLGGFPADHPLflgmagmHGTYTANMALYECDLLINIGARFDdrvtgNLAYFA------KEATVAHIDIDPA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 313 EIELRKP-HLGIVGDAKTVI-GLLNREIKDdpfclGKSNSWVESISKKAKEngekmeiqlakdvVPFNF------LTPMR 384
Cdd:PRK07710 318 EIGKNVPtEIPIVADAKQALqVLLQQEGKK-----ENHHEWLSLLKNWKEK-------------YPLSYkrnsesIKPQK 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 385 IIrDAILAVEGPSPVVvseganTMDVGRSVL--VQ----KEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDS 458
Cdd:PRK07710 380 AI-EMLYEITKGEAIV------TTDVGQHQMwaAQyypfKTPDKWVTSGGLGTMGFGLPAAIGAQLAKPDETVVAIVGDG 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 459 GFGFSAMEVETLVRYNLAVVIIVFNNGGVyGGDRRGPEEISG---PHKEDPAPTSFVpnagyhKLIEAFGGKGYIVETPD 535
Cdd:PRK07710 453 GFQMTLQELSVIKELSLPVKVVILNNEAL-GMVRQWQEEFYNqrySHSLLSCQPDFV------KLAEAYGIKGVRIDDEL 525
|
570 580
....*....|....*....|
gi 9755761 536 ELKSALAESFAARKPAVVNV 555
Cdd:PRK07710 526 EAKEQLQHAIELQEPVVIDC 545
|
|
| PRK09107 |
PRK09107 |
acetolactate synthase 3 catalytic subunit; Validated |
1-558 |
3.44e-49 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 236380 [Multi-domain] Cd Length: 595 Bit Score: 179.90 E-value: 3.44e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 1 MADKSeTTPPSIDGNVLVAKSLSHLGVTHMFGVVGIPVTSLASRAMALG-IRFIAFHNEQSAGYAASAYGYLTGKPGILL 79
Cdd:PRK09107 1 SAQKS-HMPRQMTGAEMVVQALKDQGVEHIFGYPGGAVLPIYDEIFQQDdIQHILVRHEQGAGHAAEGYARSTGKPGVVL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 80 TVSGPGCVHGLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSG 159
Cdd:PRK09107 80 VTSGPGATNAVTPLQDALMDSIPLVCITGQVPTHLIGSDAFQECDTVGITRPCTKHNWLVKDVNDLARVIHEAFHVATSG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 160 RPGGCYLDIPTDVlrQKISESEADKLVDEVERSRKeEPIRGSLrSEIESAVSLLRKAERPLIVFGKGAAYS--RAEDELK 237
Cdd:PRK09107 160 RPGPVVVDIPKDV--QFATGTYTPPQKAPVHVSYQ-PKVKGDA-EAITEAVELLANAKRPVIYSGGGVINSgpEASRLLR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 238 KLVEITGIPFLPTPMGKGLLPDTHE-------FSATAARSLAIGKCDVALVVGARLN-----WLLHFgeSPKWDKdvkfI 305
Cdd:PRK09107 236 ELVELTGFPITSTLMGLGAYPASGKnwlgmlgMHGTYEANMAMHDCDVMLCVGARFDdritgRLDAF--SPNSKK----I 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 306 LVDVSEEEI-ELRKPHLGIVGDAKTVIGLLNREIKDDPFCLGKS--NSWVESISK-KAKENgekMEIQLAKDVVpfnflT 381
Cdd:PRK09107 310 HIDIDPSSInKNVRVDVPIIGDVGHVLEDMLRLWKARGKKPDKEalADWWGQIARwRARNS---LAYTPSDDVI-----M 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 382 PMRIIRDAILAVEGPSPVVvseganTMDVGRSVL--VQ----KEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVE 455
Cdd:PRK09107 382 PQYAIQRLYELTKGRDTYI------TTEVGQHQMwaAQffgfEEPNRWMTSGGLGTMGYGLPAALGVQIAHPDALVIDIA 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 456 GDSGFGFSAMEVETLVRYNLAVVIIVFNN---GGVyggdRRGPEEISG---PHKEDPAPTSFVpnagyhKLIEAFGGKGY 529
Cdd:PRK09107 456 GDASIQMCIQEMSTAVQYNLPVKIFILNNqymGMV----RQWQQLLHGnrlSHSYTEAMPDFV------KLAEAYGAVGI 525
|
570 580
....*....|....*....|....*....
gi 9755761 530 IVETPDELKSALAESFAARKPavvnVIID 558
Cdd:PRK09107 526 RCEKPGDLDDAIQEMIDVDKP----VIFD 550
|
|
| PRK07789 |
PRK07789 |
acetolactate synthase 1 catalytic subunit; Validated |
9-557 |
1.49e-48 |
|
acetolactate synthase 1 catalytic subunit; Validated
Pssm-ID: 236098 [Multi-domain] Cd Length: 612 Bit Score: 178.25 E-value: 1.49e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 9 PPSIDGNVLVAKSLSHLGVTHMFGVVG---IPVTS--LASRAmalgIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSG 83
Cdd:PRK07789 28 PERMTGAQAVVRSLEELGVDVVFGIPGgaiLPVYDplFDSTK----VRHVLVRHEQGAGHAAEGYAQATGRVGVCMATSG 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 84 PGCVHGLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGG 163
Cdd:PRK07789 104 PGATNLVTPIADANMDSVPVVAITGQVGRGLIGTDAFQEADIVGITMPITKHNFLVTDADDIPRVIAEAFHIASTGRPGP 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 164 CYLDIPTDVLRQKISESEADKLvdEVERSRkeePIRGSLRSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEIT 243
Cdd:PRK07789 184 VLVDIPKDALQAQTTFSWPPRM--DLPGYR---PVTKPHGKQIREAAKLIAAARRPVLYVGGGVIRAEASAELRELAELT 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 244 GIPFLPTPMGKGLLPDTHE-------FSATAARSLAIGKCDVALVVGARlnwllhF-----GESPKWDKDVKFILVDVSE 311
Cdd:PRK07789 259 GIPVVTTLMARGAFPDSHPqhlgmpgMHGTVAAVAALQRSDLLIALGAR------FddrvtGKLDSFAPDAKVIHADIDP 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 312 EEI-ELRKPHLGIVGDAKTVIGLLNREIKDDPFCLGKSN--SWVESIskkakeNGEKMEIQLAKDVVPFNFLTPMRIIRd 388
Cdd:PRK07789 333 AEIgKNRHADVPIVGDVKEVIAELIAALRAEHAAGGKPDltAWWAYL------DGWRETYPLGYDEPSDGSLAPQYVIE- 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 389 AILAVEGPSPVVVSE-GANTMDVGRSVLVQKePRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEV 467
Cdd:PRK07789 406 RLGEIAGPDAIYVAGvGQHQMWAAQFIDYEK-PRTWLNSGGLGTMGYAVPAAMGAKVGRPDKEVWAIDGDGCFQMTNQEL 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 468 ETLVRYNLAVVIIVFNNGGV----------YGGDRRGPEEISGPHKedpaptsfVPNagYHKLIEAFGGKGYIVETPDEL 537
Cdd:PRK07789 485 ATCAIEGIPIKVALINNGNLgmvrqwqtlfYEERYSNTDLHTHSHR--------IPD--FVKLAEAYGCVGLRCEREEDV 554
|
570 580
....*....|....*....|.
gi 9755761 538 KSALAESFAAR-KPAVVNVII 557
Cdd:PRK07789 555 DAVIEKARAINdRPVVIDFVV 575
|
|
| PLN02470 |
PLN02470 |
acetolactate synthase |
15-557 |
2.27e-48 |
|
acetolactate synthase
Pssm-ID: 215261 [Multi-domain] Cd Length: 585 Bit Score: 177.24 E-value: 2.27e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 15 NVLVaKSLSHLGVTHMFGVVGIPVT----SLASRAMalgIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGL 90
Cdd:PLN02470 17 DILV-EALEREGVDTVFAYPGGASMeihqALTRSNC---IRNVLCRHEQGEVFAAEGYAKASGKVGVCIATSGPGATNLV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 91 AGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPT 170
Cdd:PLN02470 93 TGLADALLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRVIREAFFLASSGRPGPVLVDIPK 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 171 DVLRQKISESEADKLVDEVERSRKEEPirgSLRSEIESAVSLLRKAERPLIVFGKGAaySRAEDELKKLVEITGIPFLPT 250
Cdd:PLN02470 173 DIQQQLAVPNWNQPMKLPGYLSRLPKP---PEKSQLEQIVRLISESKRPVVYVGGGC--LNSSEELREFVELTGIPVAST 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 251 PMGKGLLPDTHEFS-------ATAARSLAIGKCDVALVVGARLNWLLHfGESPKWDKDVKFILVDVSEEEI-ELRKPHLG 322
Cdd:PLN02470 248 LMGLGAFPASDELSlqmlgmhGTVYANYAVDSADLLLAFGVRFDDRVT-GKLEAFASRASIVHIDIDPAEIgKNKQPHVS 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 323 IVGDAKTVIGLLNREIKDDPFCLGKSNSWVESISKKAKENgeKMEIQLAKDVVPfnfltPMRIIRdaILAVEGPSPVVVS 402
Cdd:PLN02470 327 VCADVKLALQGLNKLLEERKAKRPDFSAWRAELDEQKEKF--PLSYPTFGDAIP-----PQYAIQ--VLDELTDGNAIIS 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 403 EGantmdVGRSVL--VQ----KEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLA 476
Cdd:PLN02470 398 TG-----VGQHQMwaAQwykyKEPRRWLTSGGLGAMGFGLPAAIGAAAANPDAIVVDIDGDGSFIMNIQELATIHVENLP 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 477 VVIIVFNN---GGV------YGGDRRGPEEISGPHKEDPAPTSFVpnagyhKLIEAFGGKGYIVETPDELKSALAESFAA 547
Cdd:PLN02470 473 VKIMVLNNqhlGMVvqwedrFYKANRAHTYLGDPDAEAEIFPDFL------KFAEGCKIPAARVTRKSDLREAIQKMLDT 546
|
570
....*....|
gi 9755761 548 RKPAVVNVII 557
Cdd:PLN02470 547 PGPYLLDVIV 556
|
|
| PRK06882 |
PRK06882 |
acetolactate synthase 3 large subunit; |
12-558 |
2.69e-48 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 168717 [Multi-domain] Cd Length: 574 Bit Score: 177.03 E-value: 2.69e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 12 IDGNVLVAKSLSHLGVTHMFGVVGIPVTSLASRAMAL-GIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGL 90
Cdd:PRK06882 4 LSGAEMVVQSLRDEGVEYVFGYPGGSVLDIYDAIHTLgGIEHVLVRHEQAAVHMADGYARSTGKVGCVLVTSGPGATNAI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 91 AGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPT 170
Cdd:PRK06882 84 TGIATAYTDSVPLVILSGQVPSNLIGTDAFQECDMLGISRPVVKHSFIVKNAEDIPSTIKKAFYIASTGRPGPVVIDIPK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 171 DVlrqkiseseadklVDEVERSRKEEPIRGSLRS----------EIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLV 240
Cdd:PRK06882 164 DM-------------VNPANKFTYEYPEEVSLRSynptvqghkgQIKKALKALLVAKKPVLFVGGGVITAECSEQLTQFA 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 241 EITGIPFLPTPMGKGLLPDTHE-------FSATAARSLAIGKCDVALVVGARL-----NWLlhfgesPKWDKDVKFILVD 308
Cdd:PRK06882 231 QKLNLPVTSSLMGLGAYPSTDKqflgmlgMHGTYEANNAMHESDLILGIGVRFddrttNNL------AKYCPNAKVIHID 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 309 VSEEEIELRKP-HLGIVGDAKTVIGLLNREIKDDPFCLGKSN--SWVESISK-KAKENgekMEIQLAKDVVpfnflTPMR 384
Cdd:PRK06882 305 IDPTSISKNVPaYIPIVGSAKNVLEEFLSLLEEENLAKSQTDltAWWQQINEwKAKKC---LEFDRTSDVI-----KPQQ 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 385 IIRDAILAVEGPSPVVVSEGANTMDVGRSVLVQKePRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSA 464
Cdd:PRK06882 377 VVEAIYRLTNGDAYVASDVGQHQMFAALHYPFDK-PRRWINSGGAGTMGFGLPAAIGVKFAHPEATVVCVTGDGSIQMNI 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 465 MEVETLVRYNLAVVIIVFNNgGVYGGDRRGPEEI-SGPHKEdpAPTSFVPNagYHKLIEAFGGKGYIVETPDELKSALAE 543
Cdd:PRK06882 456 QELSTAKQYDIPVVIVSLNN-RFLGMVKQWQDLIySGRHSQ--VYMNSLPD--FAKLAEAYGHVGIQIDTPDELEEKLTQ 530
|
570
....*....|....*.
gi 9755761 544 SFAARKPAV-VNVIID 558
Cdd:PRK06882 531 AFSIKDKLVfVDVNVD 546
|
|
| TPP_PYR_POX_like |
cd07035 |
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP ... |
17-169 |
5.48e-48 |
|
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) and related protiens subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. For glyoxylate carboligase, which belongs to this subfamily, but lacks this conserved glutamate, the rate of the initial TPP activation step is reduced but the ensuing steps of the enzymic reaction proceed efficiently. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. This subfamily includes pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. This subfamily also includes the large catalytic subunit of acetohydroxyacid synthase (AHAS). AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate, a precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. Methanococcus jannaschii sulfopyruvate decarboxylase (MjComDE) and phosphonopyruvate decarboxylase (PpyrDc) also belong to this subfamily. PpyrDc is a homotrimeric enzyme having the PP and PYR domains tandemly arranged on the same subunit. It functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. MjComDE is a dodecamer having the PYR and PP domains on different subunits, it has six alpha (PYR/ComD) subunits and six beta (PP/ComE) subunits. MjComDE catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway.
Pssm-ID: 132918 [Multi-domain] Cd Length: 155 Bit Score: 164.24 E-value: 5.48e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 17 LVAKSLSHLGVTHMFGVVGIPVTSLASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGLSNA 96
Cdd:cd07035 2 ALVEALKAEGVDHVFGVPGGAILPLLDALARSGIRYILVRHEQGAVGMADGYARATGKPGVVLVTSGPGLTNAVTGLANA 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 9755761 97 WVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIP 169
Cdd:cd07035 82 YLDSIPLLVITGQRPTAGEGRGAFQEIDQVALFRPITKWAYRVTSPEEIPEALRRAFRIALSGRPGPVALDLP 154
|
|
| PRK06457 |
PRK06457 |
pyruvate dehydrogenase; Provisional |
17-559 |
7.95e-48 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180570 [Multi-domain] Cd Length: 549 Bit Score: 175.02 E-value: 7.95e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 17 LVAKSLSHLGVTHMFGVVGIPVTSLASRAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGLSNA 96
Cdd:PRK06457 7 VIIRVLEDNGIQRIYGIPGDSIDPLVDAIRKSKVKYVQVRHEEGAALAASVEAKITGKPSACMGTSGPGSIHLLNGLYDA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 97 WVNTWPMVMISGSCDQRDVGRGDFQELDQI---EAVKAFSKLSEKAKDVREIpdcVSRVLDRAVSGRpGGCYLDIPTDVL 173
Cdd:PRK06457 87 KMDHAPVIALTGQVESDMIGHDYFQEVNLTklfDDVAVFNQILINPENAEYI---IRRAIREAISKR-GVAHINLPVDIL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 174 RQKiseseadklvDEVERSRKEEPIRGSLRSEIESAVSLLRKAERPLIVFGKGAaySRAEDELKKLVEITGIPFLPTPMG 253
Cdd:PRK06457 163 RKS----------SEYKGSKNTEVGKVKYSIDFSRAKELIKESEKPVLLIGGGT--RGLGKEINRFAEKIGAPIIYTLNG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 254 KGLLPDTHE-------FSATAARSLAIGKCDVALVVGARlnwllhFGESPKWDKDVKFILVDVSEEEIELR-KPHLGIVG 325
Cdd:PRK06457 231 KGILPDLDPkvmggigLLGTKPSIEAMDKADLLIMLGTS------FPYVNFLNKSAKVIQVDIDNSNIGKRlDVDLSYPI 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 326 DAKTVIGLLNREiKDDPFCL---GKSNSWVESISKKAKENGEKMEIQLakdvvpFNFLTPMRIIRDAIlavegpspVVVS 402
Cdd:PRK06457 305 PVAEFLNIDIEE-KSDKFYEelkGKKEDWLDSISKQENSLDKPMKPQR------VAYIVSQKCKKDAV--------IVTD 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 403 EGANTMDVGRSVLVQKEpRTRLDAGTWGTMGVGLGYCIAAAVAS-PDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVIIV 481
Cdd:PRK06457 370 TGNVTMWTARHFRASGE-QTFIFSAWLGSMGIGVPGSVGASFAVeNKRQVISFVGDGGFTMTMMELITAKKYDLPVKIII 448
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 9755761 482 FNNGGVygGDRRGPEEISGPhkedPAPTSFVPNAGYHKLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNVIIDP 559
Cdd:PRK06457 449 YNNSKL--GMIKFEQEVMGY----PEWGVDLYNPDFTKIAESIGFKGFRLEEPKEAEEIIEEFLNTKGPAVLDAIVDP 520
|
|
| PRK07979 |
PRK07979 |
acetolactate synthase 3 large subunit; |
12-558 |
1.08e-47 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181185 [Multi-domain] Cd Length: 574 Bit Score: 175.42 E-value: 1.08e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 12 IDGNVLVAKSLSHLGVTHMFGVVGIPVTSLASRAMALG-IRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGL 90
Cdd:PRK07979 4 LSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGgIDHVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 91 AGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPT 170
Cdd:PRK07979 84 TGIATAYMDSIPLVVLSGQVATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVDLPK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 171 DVLrqkiseSEADKL---VDEVERSRKEEPIRGSLRSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPF 247
Cdd:PRK07979 164 DIL------NPANKLpyvWPESVSMRSYNPTTQGHKGQIKRALQTLVAAKKPVVYVGGGAINAACHQQLKELVEKLNLPV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 248 LPTPMGKGLLPDTHEFS-------ATAARSLAIGKCDVALVVGARL-----NWLlhfgesPKWDKDVKFILVDVSEEEIE 315
Cdd:PRK07979 238 VSSLMGLGAFPATHRQSlgmlgmhGTYEANMTMHNADVIFAVGVRFddrttNNL------AKYCPNATVLHIDIDPTSIS 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 316 LRKP-HLGIVGDAKTVIG----LLNREIKDDPFclGKSNSWVESISKKAKENGEKMEIQLAKdvvpfnfLTPMRIIRDAI 390
Cdd:PRK07979 312 KTVTaDIPIVGDARQVLEqmleLLSQESAHQPL--DEIRDWWQQIEQWRARQCLKYDTHSEK-------IKPQAVIETLW 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 391 LAVEGPSPVVVSEGANTMDVGRSVLVQKePRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETL 470
Cdd:PRK07979 383 RLTKGDAYVTSDVGQHQMFAALYYPFDK-PRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGSIQMNIQELSTA 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 471 VRYNLAVVIIVFNNGgvYGGDRRGPEEI--SGPHKE---DPAPtSFVpnagyhKLIEAFGGKGYIVETPDELKSALAESF 545
Cdd:PRK07979 462 LQYELPVLVLNLNNR--YLGMVKQWQDMiySGRHSQsymQSLP-DFV------RLAEAYGHVGIQISHPDELESKLSEAL 532
|
570
....*....|....*.
gi 9755761 546 A---ARKPAVVNVIID 558
Cdd:PRK07979 533 EqvrNNRLVFVDVTVD 548
|
|
| PRK11269 |
PRK11269 |
glyoxylate carboligase; Provisional |
10-558 |
1.14e-47 |
|
glyoxylate carboligase; Provisional
Pssm-ID: 183066 [Multi-domain] Cd Length: 591 Bit Score: 175.55 E-value: 1.14e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 10 PSIDGNVLVAKSLshlGVTHMFGVVGIPVTSLASrAM--ALGIRFIAFHNEQSAGYAASAYGYLT-GKPGILLTVSGPGC 86
Cdd:PRK11269 5 RAVDAAVLVLEKE---GVTTAFGVPGAAINPFYS-AMrkHGGIRHILARHVEGASHMAEGYTRATaGNIGVCIGTSGPAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 87 VHGLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLsekAKDVREiPDCVSRVLDRAV----SGRPG 162
Cdd:PRK11269 81 TDMITGLYSASADSIPILCITGQAPRARLHKEDFQAVDIESIAKPVTKW---AVTVRE-PALVPRVFQQAFhlmrSGRPG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 163 GCYLDIPTDVLRQKIsesEADKLVDEVERSRKEEPirgsLRSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEI 242
Cdd:PRK11269 157 PVLIDLPFDVQVAEI---EFDPDTYEPLPVYKPAA----TRAQIEKALEMLNAAERPLIVAGGGVINADASDLLVEFAEL 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 243 TGIPFLPTPMGKGLLPDTHEFSA------TAAR--SLAIGKCDVALVVGARlnWL-LHFGESPKWDKDVKFILVDVSEEE 313
Cdd:PRK11269 230 TGVPVIPTLMGWGAIPDDHPLMAgmvglqTSHRygNATLLASDFVLGIGNR--WAnRHTGSVEVYTKGRKFVHVDIEPTQ 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 314 I-ELRKPHLGIVGDAKTVIGLL---NREIKdDPFCLGKSNSWVESIskkaKENGEKMEIQLAKDVVPfnfLTPMRIIRDa 389
Cdd:PRK11269 308 IgRVFGPDLGIVSDAKAALELLvevAREWK-AAGRLPDRSAWVADC----QERKRTLLRKTHFDNVP---IKPQRVYEE- 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 390 ILAVEGPSPVVVSE-GANTMDVGRSVLVQKePRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVE 468
Cdd:PRK11269 379 MNKAFGRDTCYVSTiGLSQIAAAQFLHVYK-PRHWINCGQAGPLGWTIPAALGVRAADPDRNVVALSGDYDFQFLIEELA 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 469 TLVRYNLAVVIIVFNNGgvYGGDRRGPE-------EISGPHKEDPAPTsfvpNAGY---H-KLIEAFGGKGYIVETPDEL 537
Cdd:PRK11269 458 VGAQFNLPYIHVLVNNA--YLGLIRQAQrafdmdyCVQLAFENINSPE----LNGYgvdHvKVAEGLGCKAIRVFKPEDI 531
|
570 580
....*....|....*....|....*
gi 9755761 538 KSALAESFAA----RKPAVVNVIID 558
Cdd:PRK11269 532 APALEQAKALmaefRVPVVVEVILE 556
|
|
| PRK08978 |
PRK08978 |
acetolactate synthase 2 catalytic subunit; Reviewed |
17-559 |
5.51e-46 |
|
acetolactate synthase 2 catalytic subunit; Reviewed
Pssm-ID: 181601 [Multi-domain] Cd Length: 548 Bit Score: 170.06 E-value: 5.51e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 17 LVAKSLSHLGVTHMFGVVG---IPVTSlasramAL---GIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGL 90
Cdd:PRK08978 6 WVVHALRAQGVDTVFGYPGgaiMPVYD------ALydgGVEHLLCRHEQGAAMAAIGYARATGKVGVCIATSGPGATNLI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 91 AGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPT 170
Cdd:PRK08978 80 TGLADALLDSVPVVAITGQVSSPLIGTDAFQEIDVLGLSLACTKHSFLVQSLEELPEIMAEAFEIASSGRPGPVLVDIPK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 171 DVLrqkISESEADKLVDEVERSRKEEPirgslrSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPFLPT 250
Cdd:PRK08978 160 DIQ---LAEGELEPHLTTVENEPAFPA------AELEQARALLAQAKKPVLYVGGGVGMAGAVPALREFLAATGMPAVAT 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 251 PMGKGLLPDTHEFS-------ATAARSLAIGKCDVALVVGARLN-----WLLHFGEspkwdkDVKFILVDVSEEEI-ELR 317
Cdd:PRK08978 231 LKGLGAVEADHPYYlgmlgmhGTKAANLAVQECDLLIAVGARFDdrvtgKLNTFAP------HAKVIHLDIDPAEInKLR 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 318 KPHLGIVGDAKTVIGLLNREIKDDPfclgksnsWVESISKKAKEN-------GEK-----MEIQLAkDVVPFNFltpmri 385
Cdd:PRK08978 305 QAHVALQGDLNALLPALQQPLNIDA--------WRQHCAQLRAEHawrydhpGEAiyapaLLKQLS-DRKPADT------ 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 386 irdailavegpspVVvseganTMDVGRSvlvQ---------KEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEG 456
Cdd:PRK08978 370 -------------VV------TTDVGQH---QmwvaqhmrfTRPENFITSSGLGTMGFGLPAAIGAQVARPDDTVICVSG 427
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 457 DSGFGFSAMEVETLVRYNLAVVIIVFNN---GGVyggdrRGPEEI--SGPHKEdpapTSFVPNAGYHKLIEAFGGKGYIV 531
Cdd:PRK08978 428 DGSFMMNVQELGTIKRKQLPVKIVLLDNqrlGMV-----RQWQQLffDERYSE----TDLSDNPDFVMLASAFGIPGQTI 498
|
570 580
....*....|....*....|....*...
gi 9755761 532 ETPDELKSALAESFAARKPAVVNVIIDP 559
Cdd:PRK08978 499 TRKDQVEAALDTLLNSEGPYLLHVSIDE 526
|
|
| TPP_enzyme_N |
pfam02776 |
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; |
17-179 |
7.13e-45 |
|
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain;
Pssm-ID: 460690 [Multi-domain] Cd Length: 169 Bit Score: 156.24 E-value: 7.13e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 17 LVAKSLSHLGVTHMFGVVGIPVTSLASRAMA-LGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGLSN 95
Cdd:pfam02776 4 ALADVLKALGVDTVFGVPGGHILPLLDALAKsPGIRYVLTRHEQGAAFAADGYARATGKPGVVLVTSGPGATNALTGLAN 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 96 AWVNTWPMVMISGSCDQRDVGRGDFQ-ELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYLDIPTDVLR 174
Cdd:pfam02776 84 AYVDSVPLLVISGQRPRSLVGRGALQqELDQLALFRPVTKWAVRVTSADEIPEVLRRAFRAALSGRPGPVYLEIPLDVLL 163
|
....*
gi 9755761 175 QKISE 179
Cdd:pfam02776 164 EEVDE 168
|
|
| PRK08327 |
PRK08327 |
thiamine pyrophosphate-requiring protein; |
22-560 |
1.00e-43 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 236243 [Multi-domain] Cd Length: 569 Bit Score: 164.02 E-value: 1.00e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 22 LSHLGVTHMFGVVGIPVTSLA---SRAMALGI---RFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGLSN 95
Cdd:PRK08327 17 LKELGVDYIFINSGTDYPPIIeakARARAAGRplpEFVICPHEIVAISMAHGYALVTGKPQAVMVHVDVGTANALGGVHN 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 96 AWVNTWPMVMISG--------SCDQRDVGRGDFQE-LDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRPGGCYL 166
Cdd:PRK08327 97 AARSRIPVLVFAGrspyteegELGSRNTRIHWTQEmRDQGGLVREYVKWDYEIRRGDQIGEVVARAIQIAMSEPKGPVYL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 167 DIPTDVLRQKISESEADklvdeveRSRKEEPIR-GSLRSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGI 245
Cdd:PRK08327 177 TLPREVLAEEVPEVKAD-------AGRQMAPAPpAPDPEDIARAAEMLAAAERPVIITWRAGRTAEGFASLRRLAEELAI 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 246 P---FLPTPMGkglLPDTHEFSATAARSLAIGKCDVALVVGARLNWLLHFGEsPKWDKDVKFILVDVSEEEIELR--KPH 320
Cdd:PRK08327 250 PvveYAGEVVN---YPSDHPLHLGPDPRADLAEADLVLVVDSDVPWIPKKIR-PDADARVIQIDVDPLKSRIPLWgfPCD 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 321 LGIVGDAKTVIGLLNREIK---DDPFCLGKSNSWVESISKKAKENGEKMEIQLAKDVVPfnfLTP---MRIIRDAIlave 394
Cdd:PRK08327 326 LCIQADTSTALDQLEERLKslaSAERRRARRRRAAVRELRIRQEAAKRAEIERLKDRGP---ITPaylSYCLGEVA---- 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 395 GPSPVVVSEgantmdvgRSVLVQKEPRTRldAGTWGTMGV--GLGYCIAAAV----ASPDRLVVAVEGDSGFGFSAMEVE 468
Cdd:PRK08327 399 DEYDAIVTE--------YPFVPRQARLNK--PGSYFGDGSagGLGWALGAALgaklATPDRLVIATVGDGSFIFGVPEAA 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 469 TLV--RYNLAVVIIVFNNGGvYGGDRRG-----PEEISGPHKEDPApTSFVPNAGYHKLIEAFGGKGYIVETPDELKSAL 541
Cdd:PRK08327 469 HWVaeRYGLPVLVVVFNNGG-WLAVKEAvlevyPEGYAARKGTFPG-TDFDPRPDFAKIAEAFGGYGERVEDPEELKGAL 546
|
570 580
....*....|....*....|...
gi 9755761 542 AESFAA----RKPAVVNVIIDPF 560
Cdd:PRK08327 547 RRALAAvrkgRRSAVLDVIVDRV 569
|
|
| PDC1 |
COG3961 |
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate ... |
22-559 |
4.36e-42 |
|
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate transport and metabolism, Coenzyme transport and metabolism, General function prediction only]; TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase is part of the Pathway/BioSystem: Pyruvate oxidation
Pssm-ID: 443161 [Multi-domain] Cd Length: 545 Bit Score: 158.78 E-value: 4.36e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 22 LSHLGVTHMFGVVGIPVTSLASRAMAL-GIRFIAFHNEQSAGYAASAYGYLTGkPGILLTVSGPG---CVHGLAGlsnAW 97
Cdd:COG3961 15 LAELGIRHIFGVPGDYNLPFLDAIEAHpGIRWVGCCNELNAGYAADGYARVNG-LGALVTTYGVGelsAINGIAG---AY 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 98 VNTWPMVMISG---SCDQRD-------VGRGDFQelDQIEAVKAFSKLSEK--AKD-VREIPdcvsRVLDRAVS-GRPGg 163
Cdd:COG3961 91 AERVPVVHIVGapgTRAQRRgpllhhtLGDGDFD--HFLRMFEEVTVAQAVltPENaAAEID----RVLAAALReKRPV- 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 164 cYLDIPTDVLRQKISESEAdklvdeVERSRKEEPIRGSLRSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEIT 243
Cdd:COG3961 164 -YIELPRDVADAPIEPPEA------PLPLPPPASDPAALAAAVAAAAERLAKAKRPVILAGVEVHRFGLQEELLALAEKT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 244 GIPFLPTPMGKGLLPDTH---------EFSATAARSlAIGKCDVALVVGARLNWLLHFGESPKWDKDvKFILVDvseeei 314
Cdd:COG3961 237 GIPVATTLLGKSVLDESHpqfigtyagAASSPEVRE-YVENADCVLCLGVVFTDTNTGGFTAQLDPE-RTIDIQ------ 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 315 elrkPHLGIVGDAKtvigllnreikDDPFCLGksnSWVESISKKAKENGEKMEIQLAKDVVPF----------------- 377
Cdd:COG3961 309 ----PDSVRVGGHI-----------YPGVSLA---DFLEALAELLKKRSAPLPAPAPPPPPPPaapdapltqdrlwqrlq 370
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 378 NFLTPmriiRDAILAVEGPSpvvvSEGANTMDV--GRSVLVQkeprtrldaGTWGTMGVGLGYCIAAAVASPDRLVVAVE 455
Cdd:COG3961 371 AFLDP----GDIVVADTGTS----LFGAADLRLpeGATFIAQ---------PLWGSIGYTLPAALGAALAAPDRRVILLV 433
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 456 GDSGFGFSAMEVETLVRYNLAVVIIVFNNGGvYGGDRrgpeEISGPHkedpAPTSFVPNAGYHKLIEAFGGK---GYIVE 532
Cdd:COG3961 434 GDGAFQLTAQELSTMLRYGLKPIIFVLNNDG-YTIER----AIHGPD----GPYNDIANWDYAKLPEAFGGGnalGFRVT 504
|
570 580
....*....|....*....|....*...
gi 9755761 533 TPDELKSALAESFAARK-PAVVNVIIDP 559
Cdd:COG3961 505 TEGELEEALAAAEANTDrLTLIEVVLDK 532
|
|
| TPP_enzyme_M |
pfam00205 |
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a ... |
206-334 |
2.97e-40 |
|
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a 2-fold Rossman fold.
Pssm-ID: 425523 [Multi-domain] Cd Length: 137 Bit Score: 142.70 E-value: 2.97e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 206 IESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPFLPTPMGKGLLPDTHEFSA-------TAARSLAIGKCDV 278
Cdd:pfam00205 1 IEKAAELLKKAKRPVILAGGGVRRSGASEELRELAEKLGIPVVTTLMGKGAFPEDHPLYLgmlgmhgTPAANEALEEADL 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 9755761 279 ALVVGARLNWLLHFGESPKWDKDVKFILVDVSEEEIE-LRKPHLGIVGDAKTVIGLL 334
Cdd:pfam00205 81 VLAVGARFDDIRTTGKLPEFAPDAKIIHIDIDPAEIGkNYPVDVPIVGDAKETLEAL 137
|
|
| pyruv_oxi_spxB |
TIGR02720 |
pyruvate oxidase; Members of this family are examples of pyruvate oxidase (EC 1.2.3.3), an ... |
14-557 |
1.65e-39 |
|
pyruvate oxidase; Members of this family are examples of pyruvate oxidase (EC 1.2.3.3), an enzyme with FAD and TPP as cofactors that catalyzes the reaction pyruvate + phosphate + O2 + H2O = acetyl phosphate + CO2 + H2O2. It should not be confused with pyruvate dehydrogenase [cytochrome] (EC 1.2.2.2) as in E. coli PoxB, although the E. coli enzyme is closely homologous and has pyruvate oxidase as an alternate name. [Energy metabolism, Aerobic]
Pssm-ID: 213733 [Multi-domain] Cd Length: 575 Bit Score: 152.30 E-value: 1.65e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 14 GNVLVAKSLSHLGVTHMFGvvgIPVTSLASRAMALG-----IRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVH 88
Cdd:TIGR02720 1 ASAAVLKVLEAWGVDHIYG---IPGGSFNSTMDALSaerdrIHYIQVRHEEVGALAAAADAKLTGKIGVCFGSAGPGATH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 89 GLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSgRPGGCYLDI 168
Cdd:TIGR02720 78 LLNGLYDAKEDHVPVLALVGQVPTTGMNMDTFQEMNENPIYADVAVYNRTAMTAESLPHVIDEAIRRAYA-HNGVAVVTI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 169 PTDVLRQKISESEADKlvdevERSRKEEPIRGSLRSE-IESAVSLLRKAERPLIVFGKGAaySRAEDELKKLVEITGIPF 247
Cdd:TIGR02720 157 PVDFGWQEIPDNDYYA-----SSVSYQTPLLPAPDVEaVTRAVQTLKAAERPVIYYGIGA--RKAGEELEALSEKLKIPL 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 248 LPTPMGKGLLPDTHE-FSATAAR------SLAIGKCDVALVVGARLNwllhFGESPKWDKDVK-FILVDVSEEEIELR-K 318
Cdd:TIGR02720 230 ISTGLAKGIIEDRYPaYLGSAYRvaqkpaNEALFQADLVLFVGNNYP----FAEVSKAFKNTKyFIQIDIDPAKLGKRhH 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 319 PHLGIVGDAKTVIGLLN---REIKDDPFclgksnsWVESISKKA--KENGEKMEIQLAKDVVPFNFLTPMRII--RDAIL 391
Cdd:TIGR02720 306 TDIAVLADAKKALAAILaqvEPRESTPW-------WQANVANVKnwRAYLASLEDKTEGPLQAYQVYRAINKIaeDDAIY 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 392 AVEgpspvvvsEGANTMDVGRsvLVQKEPRTR-LDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETL 470
Cdd:TIGR02720 379 SID--------VGDININSNR--HLKMTPKNKwITSNLFATMGVGVPGAIAAKLNYPDRQVFNLAGDGAFSMTMQDLLTQ 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 471 VRYNLAVVIIVFNNgGVYGGdrrgpeeISGPHKEDPAPTSFV--PNAGYHKLIEAFGGKGYIVETPDELKSALAES--FA 546
Cdd:TIGR02720 449 VQYHLPVINIVFSN-CTYGF-------IKDEQEDTNQPLIGVdfNDADFAKIAEGVGAVGFRVNKIEQLPAVFEQAkaIK 520
|
570
....*....|.
gi 9755761 547 ARKPAVVNVII 557
Cdd:TIGR02720 521 QGKPVLIDAKI 531
|
|
| TPP_enzymes |
cd00568 |
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic ... |
386-557 |
2.19e-38 |
|
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and the branched chain alpha-keto acid dehydrogenase complexes.
Pssm-ID: 238318 [Multi-domain] Cd Length: 168 Bit Score: 138.93 E-value: 2.19e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 386 IRDAILAVEGPSPVVVSEGANTMDVGRSVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAM 465
Cdd:cd00568 2 VLAALRAALPEDAIVVNDAGNSAYWAYRYLPLRRGRRFLTSTGFGAMGYGLPAAIGAALAAPDRPVVCIAGDGGFMMTGQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 466 EVETLVRYNLAVVIIVFNNGGvYGGDRRGPEeisgPHKEDPAPTSFVPNAGYHKLIEAFGGKGYIVETPDELKSALAESF 545
Cdd:cd00568 82 ELATAVRYGLPVIVVVFNNGG-YGTIRMHQE----AFYGGRVSGTDLSNPDFAALAEAYGAKGVRVEDPEDLEAALAEAL 156
|
170
....*....|..
gi 9755761 546 AARKPAVVNVII 557
Cdd:cd00568 157 AAGGPALIEVKT 168
|
|
| PRK07064 |
PRK07064 |
thiamine pyrophosphate-binding protein; |
17-571 |
5.26e-38 |
|
thiamine pyrophosphate-binding protein;
Pssm-ID: 180820 [Multi-domain] Cd Length: 544 Bit Score: 147.44 E-value: 5.26e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 17 LVAKSLSHLGVTHMFGVVGIPVTSLASrAMAL--GIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGLS 94
Cdd:PRK07064 8 LIAAFLEQCGVKTAFGVISIHNMPILD-AIGRrgKIRFVPARGEAGAVNMADAHARVSGGLGVALTSTGTGAGNAAGALV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 95 NAWVNTWPMVMISGSCDQR--DVGRGDFQEL-DQIEAVKAFSKlseKAKDVREIPDCVSrVLDRAVS---GRPGG-CYLD 167
Cdd:PRK07064 87 EALTAGTPLLHITGQIETPylDQDLGYIHEApDQLTMLRAVSK---AAFRVRSAETALA-TIREAVRvalTAPTGpVSVE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 168 IPTDVLRQKIsESEADKLVDEVERSRKEEpirgslrSEIESAVSLLRKAERPLIVFGKGAAYSRAedELKKLVEItGIPF 247
Cdd:PRK07064 163 IPIDIQAAEI-ELPDDLAPVHVAVPEPDA-------AAVAELAERLAAARRPLLWLGGGARHAGA--EVKRLVDL-GFGV 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 248 LPTPMGKGLLPDTH-----EFSATAARSLAIGKCDVALVVGARL--NwllhfgESPKWdkdvkfilvdvseeEIELRKPH 320
Cdd:PRK07064 232 VTSTQGRGVVPEDHpaslgAFNNSAAVEALYKTCDLLLVVGSRLrgN------ETLKY--------------SLALPRPL 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 321 LGIVGDAKTVigllNREIKDDPFCLGKSNSWVESISKKAkENGEKMEIQLAKDVVP---------FNFLTPMRIIRDAIL 391
Cdd:PRK07064 292 IRVDADAAAD----GRGYPNDLFVHGDAARVLARLADRL-EGRLSVDPAFAADLRAareaavadlRKGLGPYAKLVDALR 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 392 AVEGPSPVVVSegantmDV-------GRSVLVQKEPRTRLDAgTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSA 464
Cdd:PRK07064 367 AALPRDGNWVR------DVtisnstwGNRLLPIFEPRANVHA-LGGGIGQGLAMAIGAALAGPGRKTVGLVGDGGLMLNL 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 465 MEVETLVRYNLAVVIIVFNNGG----------VYGGDRRGPEeisgPHKEDpaptsfvpnagYHKLIEAFGGKGYIVETP 534
Cdd:PRK07064 440 GELATAVQENANMVIVLMNDGGygvirniqdaQYGGRRYYVE----LHTPD-----------FALLAASLGLPHWRVTSA 504
|
570 580 590 600
....*....|....*....|....*....|....*....|
gi 9755761 535 DELKSALAESFAARKPAVVNV---IIDPFAGAESGRLQHK 571
Cdd:PRK07064 505 DDFEAVLREALAKEGPVLVEVdmlSIGPFAAAFAGPPVKK 544
|
|
| TPP_enzyme_C |
pfam02775 |
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; |
404-555 |
3.04e-36 |
|
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain;
Pssm-ID: 460689 [Multi-domain] Cd Length: 151 Bit Score: 132.32 E-value: 3.04e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 404 GANTMDVGRsVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVIIVFN 483
Cdd:pfam02775 3 GCHQMWAAQ-YYRFRPPRRYLTSGGLGTMGYGLPAAIGAKLARPDRPVVAIAGDGGFQMNLQELATAVRYNLPITVVVLN 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 9755761 484 NGGvYG-----GDRRGPEEISGPHKEDPAPTSFVpnagyhKLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNV 555
Cdd:pfam02775 82 NGG-YGmtrgqQTPFGGGRYSGPSGKILPPVDFA------KLAEAYGAKGARVESPEELEEALKEALEHDGPALIDV 151
|
|
| PRK08273 |
PRK08273 |
thiamine pyrophosphate protein; Provisional |
17-559 |
2.45e-32 |
|
thiamine pyrophosphate protein; Provisional
Pssm-ID: 181344 [Multi-domain] Cd Length: 597 Bit Score: 131.57 E-value: 2.45e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 17 LVAKSLSHLGVTHMFGVVGIPVTSLASramALG-----IRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLA 91
Cdd:PRK08273 8 FILERLREWGVRRVFGYPGDGINGLLG---ALGraddkPEFVQARHEEMAAFMAVAHAKFTGEVGVCLATSGPGAIHLLN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 92 GLSNAWVNTWPMVMISGSCDQRDVGrGDF-QELDqieavkafskLSEKAKDVRE-------IPDCVSRVLDRAVS---GR 160
Cdd:PRK08273 85 GLYDAKLDHVPVVAIVGQQARAALG-GHYqQEVD----------LQSLFKDVAGafvqmvtVPEQLRHLVDRAVRtalAE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 161 PGGCYLDIPTDVlrQKISESEADKLVDEVERSRKEEPIRGSLRSE-IESAVSLLRKAERPLIVFGKGAAysRAEDELKKL 239
Cdd:PRK08273 154 RTVTAVILPNDV--QELEYEPPPHAHGTVHSGVGYTRPRVVPYDEdLRRAAEVLNAGRKVAILVGAGAL--GATDEVIAV 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 240 VEITGIPFLPTPMGKGLLPDTHEFSA-------TAARSLAIGKCDVALVVGARL---NWLLHFGESpkwdkdvKFILVDV 309
Cdd:PRK08273 230 AERLGAGVAKALLGKAALPDDLPWVTgsigllgTKPSYELMRECDTLLMVGSSFpysEFLPKEGQA-------RGVQIDI 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 310 SEEEIELRKP-HLGIVGDAKT----VIGLLNReiKDDpfclgksNSWVESISKKAKENGEKMEIQLAKDVVPFNfltPMR 384
Cdd:PRK08273 303 DGRMLGLRYPmEVNLVGDAAEtlraLLPLLER--KKD-------RSWRERIEKWVARWWETLEARAMVPADPVN---PQR 370
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 385 IIRDaiLAVEGPSPVVVseganTMDVG-------RSVLVQKEPRTRLdAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGD 457
Cdd:PRK08273 371 VFWE--LSPRLPDNAIL-----TADSGscanwyaRDLRMRRGMMASL-SGTLATMGPAVPYAIAAKFAHPDRPVIALVGD 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 458 SGFGFSAM-EVETLVRY-----NLAVVIIVFNNGG---------VYGGDRRGPEeisgphkedpapTSFVPNAGYHKLIE 522
Cdd:PRK08273 443 GAMQMNGMaELITVAKYwrqwsDPRLIVLVLNNRDlnqvtweqrVMEGDPKFEA------------SQDLPDVPYARFAE 510
|
570 580 590
....*....|....*....|....*....|....*..
gi 9755761 523 AFGGKGYIVETPDELKSALAESFAARKPAVVNVIIDP 559
Cdd:PRK08273 511 LLGLKGIRVDDPEQLGAAWDEALAADRPVVLEVKTDP 547
|
|
| TPP_AHAS |
cd02015 |
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding ... |
418-559 |
1.02e-31 |
|
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate. 2-Acetolactate is the precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. In addition to requiring TPP and a divalent metal ion as cofactors, AHAS requires FAD.
Pssm-ID: 238973 [Multi-domain] Cd Length: 186 Bit Score: 121.07 E-value: 1.02e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 418 KEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVIIVFNNGgvYGGDRRGPEE 497
Cdd:cd02015 38 KKPRSWLTSGGLGTMGFGLPAAIGAKVARPDKTVICIDGDGSFQMNIQELATAAQYNLPVKIVILNNG--SLGMVRQWQE 115
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 9755761 498 ISgpHKEDPAPTSFVPNAGYHKLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNVIIDP 559
Cdd:cd02015 116 LF--YEGRYSHTTLDSNPDFVKLAEAYGIKGLRVEKPEELEAALKEALASDGPVLLDVLVDP 175
|
|
| TPP_POX |
cd02014 |
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; ... |
384-559 |
1.43e-30 |
|
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. It requires FAD in addition to TPP and a divalent cation as cofactors.
Pssm-ID: 238972 [Multi-domain] Cd Length: 178 Bit Score: 117.63 E-value: 1.43e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 384 RIIRDAILAVEGpspvvvseGANTMDVGRSVLVQKEPRTRLdAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFS 463
Cdd:cd02014 14 RAPDDAIFTIDV--------GNVTVWAARHLRMNGKQRFIL-SGLLATMGNGLPGAIAAKLAYPDRQVIALSGDGGFAML 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 464 AMEVETLVRYNLAVVIIVFNNgGVYGgdrrgpeEISGPHKEDPAPTSFV--PNAGYHKLIEAFGGKGYIVETPDELKSAL 541
Cdd:cd02014 85 MGDLITAVKYNLPVIVVVFNN-SDLG-------FIKWEQEVMGQPEFGVdlPNPDFAKIAEAMGIKGIRVEDPDELEAAL 156
|
170
....*....|....*...
gi 9755761 542 AESFAARKPAVVNVIIDP 559
Cdd:cd02014 157 DEALAADGPVVIDVVTDP 174
|
|
| TPP_ALS |
cd02010 |
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; ... |
382-558 |
4.98e-28 |
|
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2 molecules of pyruvate to acetolactate and carbon dioxide. ALS does not contain FAD, and requires TPP and a divalent metal cation for activity.
Pssm-ID: 238968 [Multi-domain] Cd Length: 177 Bit Score: 110.46 E-value: 4.98e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 382 PMRIIRDaILAVEGPSPVVVSE-GANTMDVGRSVLVQkEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGF 460
Cdd:cd02010 1 PQRIVHD-LRAVMGDDDIVLLDvGAHKIWMARYYRTY-APNTCLISNGLATMGVALPGAIGAKLVYPDRKVVAVSGDGGF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 461 GFSAMEVETLVRYNLAVVIIVFNNGGvYGGDRRGPEEISGPHKE-DPAPTSFVpnagyhKLIEAFGGKGYIVETPDELKS 539
Cdd:cd02010 79 MMNSQELETAVRLKIPLVVLIWNDNG-YGLIKWKQEKEYGRDSGvDFGNPDFV------KYAESFGAKGYRIESADDLLP 151
|
170
....*....|....*....
gi 9755761 540 ALAESFAARKPAVVNVIID 558
Cdd:cd02010 152 VLERALAADGVHVIDCPVD 170
|
|
| PRK09124 |
PRK09124 |
ubiquinone-dependent pyruvate dehydrogenase; |
17-558 |
3.51e-27 |
|
ubiquinone-dependent pyruvate dehydrogenase;
Pssm-ID: 181661 [Multi-domain] Cd Length: 574 Bit Score: 115.86 E-value: 3.51e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 17 LVAKSLSHLGVTHMFGVVGIPVTSL--ASRAMAlGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGLS 94
Cdd:PRK09124 8 YIAKTLEQAGVKRIWGVTGDSLNGLsdSLRRMG-TIEWMHTRHEEVAAFAAGAEAQLTGELAVCAGSCGPGNLHLINGLF 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 95 NAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPdcvsRVLDRAVS---GRPGGCYLDIPTD 171
Cdd:PRK09124 87 DCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQELFRECSHYCELVSNPEQLP----RVLAIAMRkaiLNRGVAVVVLPGD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 172 VLRQKISESEAdklvdeVERSRKEEPIRGSLRSEIESAVSLLRKAERPLIVFGKGAAysRAEDELKKLVEITGIPFLPTP 251
Cdd:PRK09124 163 VALKPAPERAT------PHWYHAPQPVVTPAEEELRKLAALLNGSSNITLLCGSGCA--GAHDELVALAETLKAPIVHAL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 252 MGK--------------GLLpdthEFSATAArslAIGKCDVALVVGARlnwllhFGESPKWDKDVKFILVDVSEEEIELR 317
Cdd:PRK09124 235 RGKehveydnpydvgmtGLI----GFSSGYH---AMMNCDTLLMLGTD------FPYRQFYPTDAKIIQIDINPGSLGRR 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 318 KP-HLGIVGDAKTVI-GLLNR-EIKDDPFCLGKSNSWVESISK------KAKENGEKMEIQlakdvvpfnFLTpmRII-- 386
Cdd:PRK09124 302 SPvDLGLVGDVKATLaALLPLlEEKTDRKFLDKALEHYRKARKglddlaVPSDGGKPIHPQ---------YLA--RQIse 370
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 387 ---RDAILAVEGPSPVVVSEGANTMDVGRSVLvqkeprtrldaGTW--GTMGVGLGYCIAAAVASPDRLVVAVEGDSGFG 461
Cdd:PRK09124 371 faaDDAIFTCDVGTPTVWAARYLKMNGKRRLL-----------GSFnhGSMANAMPQALGAQAAHPGRQVVALSGDGGFS 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 462 FSAMEVETLVRYNLAVVIIVFNNGGV--------------YGGDRRGPEeisgphkedpaptsfvpnagYHKLIEAFGGK 527
Cdd:PRK09124 440 MLMGDFLSLVQLKLPVKIVVFNNSVLgfvamemkaggyltDGTDLHNPD--------------------FAAIAEACGIT 499
|
570 580 590
....*....|....*....|....*....|.
gi 9755761 528 GYIVETPDELKSALAESFAARKPAVVNVIID 558
Cdd:PRK09124 500 GIRVEKASELDGALQRAFAHDGPALVDVVTA 530
|
|
| TPP_Xsc_like |
cd02013 |
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of ... |
378-563 |
1.19e-24 |
|
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of proteins similar to Alcaligenes defragrans sulfoacetaldehyde acetyltransferase (Xsc). Xsc plays a key role in the degradation of taurine, catalyzing the desulfonation of 2-sulfoacetaldehyde into sulfite and acetyl phosphate. This enzyme requires TPP and divalent metal ions for activity.
Pssm-ID: 238971 [Multi-domain] Cd Length: 196 Bit Score: 101.43 E-value: 1.19e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 378 NFLTPMRIIRDaiLAVEGPSPVVVS-EGANTMDVGRSVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVVAVEG 456
Cdd:cd02013 2 NPMHPRQVLRE--LEKAMPEDAIVStDIGNICSVANSYLRFEKPRSFIAPLSFGNCGYALPAIIGAKAAAPDRPVVAIAG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 457 DSGFGFSAMEVETLVRYNLAVVIIVFNNGGvYGGDRRGPEEISGphkedpapTSFV----PNAGYHKLIEAFGGKGYIVE 532
Cdd:cd02013 80 DGAWGMSMMEIMTAVRHKLPVTAVVFRNRQ-WGAEKKNQVDFYN--------NRFVgtelESESFAKIAEACGAKGITVD 150
|
170 180 190
....*....|....*....|....*....|....
gi 9755761 533 TPDELKSALAESFAAR---KPAVVNVIIDPFAGA 563
Cdd:cd02013 151 KPEDVGPALQKAIAMMaegKTTVIEIVCDQELGD 184
|
|
| TPP_PYR_POX |
cd07039 |
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) ... |
17-176 |
2.76e-24 |
|
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. Lactobacillus plantarum POX is a homotetramer (dimer-of-homodimers), having two active sites per homodimer lying between PYR and PP domains of different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate.
Pssm-ID: 132922 [Multi-domain] Cd Length: 164 Bit Score: 99.55 E-value: 2.76e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 17 LVAKSLSHLGVTHMFGVVGipvTSLASRAMAL----GIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAG 92
Cdd:cd07039 5 VIVETLENWGVKRVYGIPG---DSINGLMDALrregKIEFIQVRHEEAAAFAASAEAKLTGKLGVCLGSSGPGAIHLLNG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 93 LSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGRpGGCYLDIPTDV 172
Cdd:cd07039 82 LYDAKRDRAPVLAIAGQVPTDELGTDYFQEVDLLALFKDVAVYNETVTSPEQLPELLDRAIRTAIAKR-GVAVLILPGDV 160
|
....
gi 9755761 173 LRQK 176
Cdd:cd07039 161 QDAP 164
|
|
| PRK06546 |
PRK06546 |
pyruvate dehydrogenase; Provisional |
26-561 |
1.42e-23 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180614 [Multi-domain] Cd Length: 578 Bit Score: 104.68 E-value: 1.42e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 26 GVTHMFGVVGI---PVTSLASRAMalGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGLSNAWVNTWP 102
Cdd:PRK06546 17 GVKRIYGIVGDslnPIVDAVRRTG--GIEWVHVRHEEAAAFAAAAEAQLTGKLAVCAGSCGPGNLHLINGLYDAHRSGAP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 103 MVMISGSCDQRDVGRGDFQEL--DQIeaVKAFSKLSEKAKDVREIPdcvsRVLDRAVS---GRPGGCYLDIPTDVLRQKI 177
Cdd:PRK06546 95 VLAIASHIPSAQIGSGFFQEThpDRL--FVECSGYCEMVSSAEQAP----RVLHSAIQhavAGGGVSVVTLPGDIADEPA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 178 SESEADKLVdeversRKEEPIRGSLRSEIESAVSLLRKAERPLIVFGKGAAYSRaeDELKKLVEITGIPFLPTPMGK--- 254
Cdd:PRK06546 169 PEGFAPSVI------SPRRPTVVPDPAEVRALADAINEAKKVTLFAGAGVRGAH--AEVLALAEKIKAPVGHSLRGKewi 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 255 -----------GLLpdthEFSATAArslAIGKCDVALVVGARL---NWLlhfgespkwdKDVKFILVDVSEEEIELRKP- 319
Cdd:PRK06546 241 qydnpfdvgmsGLL----GYGAAHE---AMHEADLLILLGTDFpydQFL----------PDVRTAQVDIDPEHLGRRTRv 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 320 HLGIVGDAKTVIGLLN---REIKDDPFC---LGKSNSWVESISKKAKENGEKME-I----------QLAKDvvpfnfltp 382
Cdd:PRK06546 304 DLAVHGDVAETIRALLplvKEKTDRRFLdrmLKKHARKLEKVVGAYTRKVEKHTpIhpeyvasildELAAD--------- 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 383 mriirDAILAVEgpspvvvsEGANTMDVGRsvLVQKEPRTRLdAGTW--GTMGVGLGYCIAAAVASPDRLVVAVEGDSGF 460
Cdd:PRK06546 375 -----DAVFTVD--------TGMCNVWAAR--YITPNGRRRV-IGSFrhGSMANALPHAIGAQLADPGRQVISMSGDGGL 438
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 461 GFSAMEVETLVRYNLAVVIIVFNN---GGV-----------YGGDrrgpeeisgphkedpaptsfVPNAGYHKLIEAFGG 526
Cdd:PRK06546 439 SMLLGELLTVKLYDLPVKVVVFNNstlGMVklemlvdglpdFGTD--------------------HPPVDYAAIAAALGI 498
|
570 580 590
....*....|....*....|....*....|....*
gi 9755761 527 KGYIVETPDELKSALAESFAARKPAVVNVIIDPFA 561
Cdd:PRK06546 499 HAVRVEDPKDVRGALREAFAHPGPALVDVVTDPNA 533
|
|
| TPP_PDC_IPDC |
cd02005 |
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of ... |
427-560 |
2.54e-23 |
|
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of pyruvate to acetaldehyde and CO2. It is able to utilize other 2-oxo acids as substrates. In plants and various plant-associated bacteria, IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway, a tryptophan-dependent biosynthetic route to indole-3-acetaldehyde (IAA). IPDC catalyzes the decarboxylation of IPA to IAA. Both PDC and IPDC depend on TPP and Mg2+ as cofactors.
Pssm-ID: 238963 [Multi-domain] Cd Length: 183 Bit Score: 97.22 E-value: 2.54e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 427 GTWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVIIVFNNGGvYGGDRrgpeEISGPHKedp 506
Cdd:cd02005 47 PLWGSIGYSVPAALGAALAAPDRRVILLVGDGSFQMTVQELSTMIRYGLNPIIFLINNDG-YTIER----AIHGPEA--- 118
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 9755761 507 aptSF--VPNAGYHKLIEAFG----GKGYIVETPDELKSALAES-FAARKPAVVNVIIDPF 560
Cdd:cd02005 119 ---SYndIANWNYTKLPEVFGggggGLSFRVKTEGELDEALKDAlFNRDKLSLIEVILPKD 176
|
|
| TPP_BFDC |
cd02002 |
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins ... |
380-557 |
9.90e-22 |
|
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of benzoylformate to benzaldehyde and carbon dioxide. This enzyme is dependent on TPP and a divalent metal cation as cofactors.
Pssm-ID: 238960 [Multi-domain] Cd Length: 178 Bit Score: 92.66 E-value: 9.90e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 380 LTPMRIIRdAILAVEGPSPVVVSEGANTMDVGRSVLVQKEPRTRLDAGTwGTMGVGLGYCIAAAVASPDRLVVAVEGDSG 459
Cdd:cd02002 1 LTPEYLAA-ALAAALPEDAIIVDEAVTNGLPLRDQLPLTRPGSYFTLRG-GGLGWGLPAAVGAALANPDRKVVAIIGDGS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 460 FGFSAMEVETLVRYNLAVVIIVFNNGG---------VYGGDRRGPEEISGPHKEDPAPtSFVpnagyhKLIEAFGGKGYI 530
Cdd:cd02002 79 FMYTIQALWTAARYGLPVTVVILNNRGygalrsflkRVGPEGPGENAPDGLDLLDPGI-DFA------AIAKAFGVEAER 151
|
170 180
....*....|....*....|....*..
gi 9755761 531 VETPDELKSALAESFAARKPAVVNVII 557
Cdd:cd02002 152 VETPEELDEALREALAEGGPALIEVVV 178
|
|
| PRK07092 |
PRK07092 |
benzoylformate decarboxylase; Reviewed |
22-558 |
9.55e-18 |
|
benzoylformate decarboxylase; Reviewed
Pssm-ID: 235931 [Multi-domain] Cd Length: 530 Bit Score: 86.55 E-value: 9.55e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 22 LSHLGVTHMFGVVGipVTSLAS-RAMALGIRFIAFHNEQSAGYAASAYGYLTGKPGILLTVSGPGCVHGLAGLSNAWVNT 100
Cdd:PRK07092 22 LRRFGITTVFGNPG--STELPFlRDFPDDFRYVLGLQEAVVVGMADGYAQATGNAAFVNLHSAAGVGNAMGNLFTAFKNH 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 101 WPMVMISGSCDQRDVGRGDFqeLDQIEAV---KAFSKLS---EKAKDVreiPDCVSRVLDRAVSGRPGGCYLDIPTDvlr 174
Cdd:PRK07092 100 TPLVITAGQQARSILPFEPF--LAAVQAAelpKPYVKWSiepARAEDV---PAAIARAYHIAMQPPRGPVFVSIPYD--- 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 175 qkisesEADKLVDEVERSRKEEPIRGSlRSEIESAVSLLRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPFLPTPM-G 253
Cdd:PRK07092 172 ------DWDQPAEPLPARTVSSAVRPD-PAALARLGDALDAARRPALVVGPAVDRAGAWDDAVRLAERHRAPVWVAPMsG 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 254 KGLLPDTHEFSA---TAAR---SLAIGKCDVALVVGARLNWLLHFGESPKWDKDVKfiLVDVSEEEIELRKPHLG--IVG 325
Cdd:PRK07092 245 RCSFPEDHPLFAgflPASRekiSALLDGHDLVLVIGAPVFTYHVEGPGPHLPEGAE--LVQLTDDPGEAAWAPMGdaIVG 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 326 DAKTVIGLLNREIKDDpfclGKSNSWVESISKKAKENGEKME----IQLAKDVVPfnfltpmriiRDAILAVEGPSpvvv 401
Cdd:PRK07092 323 DIRLALRDLLALLPPS----ARPAPPARPMPPPAPAPGEPLSvafvLQTLAALRP----------ADAIVVEEAPS---- 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 402 segantmdvGRSVLVQKEPRTRldAGTWGTMGVG-LGYCIAAAV----ASPDRLVVAVEGDSGFGFSAMEVETLVRYNLA 476
Cdd:PRK07092 385 ---------TRPAMQEHLPMRR--QGSFYTMASGgLGYGLPAAVgvalAQPGRRVIGLIGDGSAMYSIQALWSAAQLKLP 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 477 VVIIVFNNGGvYGGDRrgpeEISGPHKEDPAPTSFVPNAGYHKLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNVI 556
Cdd:PRK07092 454 VTFVILNNGR-YGALR----WFAPVFGVRDVPGLDLPGLDFVALARGYGCEAVRVSDAAELADALARALAADGPVLVEVE 528
|
..
gi 9755761 557 ID 558
Cdd:PRK07092 529 VA 530
|
|
| PLN02573 |
PLN02573 |
pyruvate decarboxylase |
2-549 |
3.13e-16 |
|
pyruvate decarboxylase
Pssm-ID: 215311 [Multi-domain] Cd Length: 578 Bit Score: 81.67 E-value: 3.13e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 2 ADKSETTPPSIDGNV--LVAKSLSHLGVTHMFGVVGIPVTSLASRAMAL-GIRFIAFHNEQSAGYAASAYGYL--TGKPG 76
Cdd:PLN02573 4 APKPATPVSSSDATLgrHLARRLVEIGVTDVFSVPGDFNLTLLDHLIAEpGLNLIGCCNELNAGYAADGYARArgVGACV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 77 ILLTVSGPGCVHGLAGlsnAWVNTWPMVMISGSCDQRD----------VGRGDF-QELDQIEAVKAFSKLSEKAKDVREI 145
Cdd:PLN02573 84 VTFTVGGLSVLNAIAG---AYSENLPVICIVGGPNSNDygtnrilhhtIGLPDFsQELRCFQTVTCYQAVINNLEDAHEL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 146 pdcvsrvLDRAVSgrpggcyldipTDVLRQK---ISESeaDKLVDEVERSRKEEPI----------RGSLRSEIESAVSL 212
Cdd:PLN02573 161 -------IDTAIS-----------TALKESKpvyISVS--CNLAAIPHPTFSREPVpffltprlsnKMSLEAAVEAAAEF 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 213 LRKAERPLIVFGKGAAYSRAEDELKKLVEITGIPFLPTPMGKGLLPDTHE-FSATAARSLAIGKC-------DVALVVGA 284
Cdd:PLN02573 221 LNKAVKPVLVGGPKLRVAKACKAFVELADASGYPVAVMPSAKGLVPEHHPhFIGTYWGAVSTPFCaeivesaDAYLFAGP 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 285 RLNWLLHFGESPKWDKDvKFILVDvseeeielrkPHLGIVGDAKTVIGLLnreIKDdpfclgksnsWVESISKKAKENGE 364
Cdd:PLN02573 301 IFNDYSSVGYSLLLKKE-KAIIVQ----------PDRVTIGNGPAFGCVL---MKD----------FLEALAKRVKKNTT 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 365 KME----IQLAKDVVPFNFLT-PMR--IIRDAILAVEGPSPVVVSEgantmdVGRSVL-VQKeprTRLDAGT-------W 429
Cdd:PLN02573 357 AYEnykrIFVPEGEPLKSEPGePLRvnVLFKHIQKMLSGDTAVIAE------TGDSWFnCQK---LKLPEGCgyefqmqY 427
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 430 GTMG--VG--LGYciaaAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVIIVFNNGGvYGGDrrgpEEI-SGPHke 504
Cdd:PLN02573 428 GSIGwsVGatLGY----AQAAPDKRVIACIGDGSFQVTAQDVSTMIRCGQKSIIFLINNGG-YTIE----VEIhDGPY-- 496
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 9755761 505 dpaptSFVPNAGYHKLIEAF-GGKGYI----VETPDELKSALAESFAARK 549
Cdd:PLN02573 497 -----NVIKNWNYTGLVDAIhNGEGKCwtakVRTEEELIEAIATATGEKK 541
|
|
| TPP_IolD |
cd02003 |
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins ... |
436-566 |
4.57e-12 |
|
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism.
Pssm-ID: 238961 [Multi-domain] Cd Length: 205 Bit Score: 65.40 E-value: 4.57e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 436 LGYCIAAAV----ASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVIIVFNNGGV---------YGGDRRGPE-----E 497
Cdd:cd02003 50 MGYEIAAGLgaklAKPDREVYVLVGDGSYLMLHSEIVTAVQEGLKIIIVLFDNHGFgcinnlqesTGSGSFGTEfrdrdQ 129
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 9755761 498 ISGPHKEDPAPTSFVPNAgyhkliEAFGGKGYIVETPDELKSALAESFAARKPAVVNVIIDPFAGAESG 566
Cdd:cd02003 130 ESGQLDGALLPVDFAANA------RSLGARVEKVKTIEELKAALAKAKASDRTTVIVIKTDPKSMTPGY 192
|
|
| TPP_PYR_PDC_IPDC_like |
cd07038 |
Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase ... |
22-170 |
7.04e-10 |
|
Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. Also belonging to this group is Mycobacterium tuberculosis alpha-keto acid decarboxylase (MtKDC) which participates in amino acid degradation via the Ehrlich pathway, and Lactococcus lactis branched-chain keto acid decarboxylase (KdcA) an enzyme identified as being involved in cheese ripening, which exhibits a very broad substrate range in the decarboxylation and carboligation reactions.
Pssm-ID: 132921 [Multi-domain] Cd Length: 162 Bit Score: 57.89 E-value: 7.04e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 22 LSHLGVTHMFGVVGipvtslaSRAMAL--------GIRFIAFHNEQSAGYAASAYGYLTGkPGILLTVSGPG---CVHGL 90
Cdd:cd07038 7 LKQLGVKHVFGVPG-------DYNLPLldaieenpGLRWVGNCNELNAGYAADGYARVKG-LGALVTTYGVGelsALNGI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 91 AGlsnAWVNTWPMVMISGSCDQRD----------VGRGDFQEldQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVS-G 159
Cdd:cd07038 79 AG---AYAEHVPVVHIVGAPSTKAqasglllhhtLGDGDFDV--FLKMFEEITCAAARLTDPENAAEEIDRVLRTALReS 153
|
170
....*....|.
gi 9755761 160 RPGgcYLDIPT 170
Cdd:cd07038 154 RPV--YIEIPR 162
|
|
| PRK12474 |
PRK12474 |
hypothetical protein; Provisional |
64-557 |
1.74e-09 |
|
hypothetical protein; Provisional
Pssm-ID: 139002 [Multi-domain] Cd Length: 518 Bit Score: 60.27 E-value: 1.74e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 64 AASAYGYLTGKPGILLTVSGPGCVHGLAGLSNAWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVR 143
Cdd:PRK12474 58 AADGYGRIAGKPAVTLLHLGPGLANGLANLHNARRAASPIVNIVGDHAVEHLQYDAPLTSDIDGFARPVSRWVHRSASAG 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 144 EIPDCVSRVLDRAVSGRPGGCYLDIPTDVLRQKisESEADKLVDEVERSRKE----EPIRGSLRSEIESAVsLLRKA--- 216
Cdd:PRK12474 138 AVDSDVARAVQAAQSAPGGIATLIMPADVAWNE--AAYAAQPLRGIGPAPVAaetvERIAALLRNGKKSAL-LLRGSalr 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 217 ERPLIVFGKGAAysraedelKKLVEITGIPFLP-TPMGKGL-----LPDTHEFSATAARSLaigkcDVALVVGAR--LNW 288
Cdd:PRK12474 215 GAPLEAAGRIQA--------KTGVRLYCDTFAPrIERGAGRvpierIPYFHEQITAFLKDV-----EQLVLVGAKppVSF 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 289 LLHFGEsPKWdkdvkfiLVDVSEEEIELRKPHlgivGDAKTVIGLLNREIkDDPfclgksnswvesiskkakeNGEKMEI 368
Cdd:PRK12474 282 FAYPGK-PSW-------GAPPGCEIVYLAQPD----EDLAQALQDLADAV-DAP-------------------AEPAART 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 369 QLAKDVVPFNFLTPMRIIRdaILAVEGPSPVVVSEGANTMDVGRSVLVQK-EPRTRLDAgTWGTMGVGLGYCIAAAVASP 447
Cdd:PRK12474 330 PLALPALPKGALNSLGVAQ--LIAHRTPDQAIYADEALTSGLFFDMSYDRaRPHTHLPL-TGGSIGQGLPLAAGAAVAAP 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 448 DRLVVAVEGDSGFGFSAMEVETLVRYNLAVVIIVFNN---GGVYGGDRRGPEEISGPHKEDPAPTSfVPNAGYHKLIEAF 524
Cdd:PRK12474 407 DRKVVCPQGDGGAAYTMQALWTMARENLDVTVVIFANrsyAILNGELQRVGAQGAGRNALSMLDLH-NPELNWMKIAEGL 485
|
490 500 510
....*....|....*....|....*....|...
gi 9755761 525 GGKGYIVETPDELKSALAESFAARKPAVVNVII 557
Cdd:PRK12474 486 GVEASRATTAEEFSAQYAAAMAQRGPRLIEAMI 518
|
|
| TPP_enzyme_PYR |
cd06586 |
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine ... |
17-169 |
1.77e-09 |
|
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine pyrophosphate (TPP) family, pyrimidine (PYR) binding domain; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this group. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. In the case of 2-oxoisovalerate dehydrogenase (2OXO), sulfopyruvate decarboxylase (ComDE), and the E1 component of human pyruvate dehydrogenase complex (E1- PDHc) the PYR and PP domains appear on different subunits. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. For many of these enzymes the active sites lie between PP and PYR domains on different subunits. However, for the homodimeric enzymes 1-deoxy-D-xylulose 5-phosphate synthase (DXS) and Desulfovibrio africanus pyruvate:ferredoxin oxidoreductase (PFOR), each active site lies at the interface of the PYR and PP domains from the same subunit.
Pssm-ID: 132915 [Multi-domain] Cd Length: 154 Bit Score: 56.58 E-value: 1.77e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 17 LVAKSLSHLGVTHMFGVVGIPVTSLASRAMAL-GIRFIAFHNEQSAGYAASAYGYLTGkPGILLTVSGPGCVHGLAGLSN 95
Cdd:cd06586 2 AFAEVLTAWGVRHVFGYPGDEISSLLDALREGdKRIIDTVIHELGAAGAAAGYARAGG-PPVVIVTSGTGLLNAINGLAD 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 9755761 96 AWVNTWPMVMISGSCDQRDVGRGDFQELDQIEAVKAFSKLSEKAKDVREIPDCVSRVLDRAVSGrPGGCYLDIP 169
Cdd:cd06586 81 AAAEHLPVVFLIGARGISAQAKQTFQSMFDLGMYRSIPEANISSPSPAELPAGIDHAIRTAYAS-QGPVVVRLP 153
|
|
| PRK07586 |
PRK07586 |
acetolactate synthase large subunit; |
428-557 |
1.72e-08 |
|
acetolactate synthase large subunit;
Pssm-ID: 236063 [Multi-domain] Cd Length: 514 Bit Score: 57.16 E-value: 1.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 428 TWGTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMEVETLVRYNLAVVIIVFNNGGvY----------GGDRRGPEE 497
Cdd:PRK07586 383 TGGAIGQGLPLATGAAVACPDRKVLALQGDGSAMYTIQALWTQARENLDVTTVIFANRA-YailrgelarvGAGNPGPRA 461
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 498 ISGPHKEDPAPtSFVpnagyhKLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNVII 557
Cdd:PRK07586 462 LDMLDLDDPDL-DWV------ALAEGMGVPARRVTTAEEFADALAAALAEPGPHLIEAVV 514
|
|
| TPP_Gcl |
cd02006 |
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins ... |
373-558 |
1.98e-07 |
|
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the condensation of two molecules of glyoxylate to give tartronic semialdehyde and carbon dioxide. This enzyme requires TPP, magnesium ion and FAD as cofactors.
Pssm-ID: 238964 [Multi-domain] Cd Length: 202 Bit Score: 51.90 E-value: 1.98e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 373 DVVPfnfLTPMRIIRDAILAVeGPSPVVVSEGANTMDVGRSVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAVASPDRLVV 452
Cdd:cd02006 4 DDVP---IKPQRVYEEMNKAF-GRDVRYVTTIGLSQIAGAQMLHVYKPRHWINCGQAGPLGWTVPAALGVAAADPDRQVV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 453 AVEGDSGFGFSAMEVETLVRYNLAVVIIVFNNG--GVYGGDRRGPE---EISGPHKEDPAPTSFVPNAGYHKLIEAFGGK 527
Cdd:cd02006 80 ALSGDYDFQFMIEELAVGAQHRIPYIHVLVNNAylGLIRQAQRAFDmdyQVNLAFENINSSELGGYGVDHVKVAEGLGCK 159
|
170 180 190
....*....|....*....|....*....|....*
gi 9755761 528 GYIVETPDELKSAL--AESFAA--RKPAVVNVIID 558
Cdd:cd02006 160 AIRVTKPEELAAAFeqAKKLMAehRVPVVVEAILE 194
|
|
| TPP_IOR_alpha |
cd02008 |
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of ... |
409-553 |
2.83e-04 |
|
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as indolepyruvate or phenylpyruvate, which are generated by the transamination of aromatic amino acids, to the corresponding aryl acetyl-CoA.
Pssm-ID: 238966 [Multi-domain] Cd Length: 178 Bit Score: 41.88 E-value: 2.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 409 DVGRSVLVQKEPRTRLDAGTwgTMGVGLGYCIAAAVASPDRLVVAVEGDSGFGFSAMeveTLVR---YN-LAVVIIVFNN 484
Cdd:cd02008 32 DIGCYTLGALPPLNAIDTCT--CMGASIGVAIGMAKASEDKKVVAVIGDSTFFHSGI---LGLInavYNkANITVVILDN 106
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 9755761 485 G--GVYGGdrrgpEEISGPHKEDPAPTSFVPNAgyhKLIEAFGGKGYIVETPDELKS---ALAESFAARKPAVV 553
Cdd:cd02008 107 RttAMTGG-----QPHPGTGKTLTEPTTVIDIE---ALVRAIGVKRVVVVDPYDLKAireELKEALAVPGVSVI 172
|
|
| TPP_SHCHC_synthase |
cd02009 |
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of ... |
430-558 |
6.16e-04 |
|
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key role in the menaquinone biosynthetic pathway, converting isochorismate and 2-oxoglutarate to SHCHC, pyruvate and carbon dioxide. The enzyme requires TPP and a divalent metal cation for activity.
Pssm-ID: 238967 [Multi-domain] Cd Length: 175 Bit Score: 41.04 E-value: 6.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 430 GTMGVGLGYCIAAavaspDRLVVAVEGDSGF-----GFSAMEVETLvryNLavVIIVFNNGGvyGGD-RRGPEEISGPHK 503
Cdd:cd02009 55 GTLSTALGIALAT-----DKPTVLLTGDLSFlhdlnGLLLGKQEPL---NL--TIVVINNNG--GGIfSLLPQASFEDEF 122
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 9755761 504 ED--PAPTSFvpNAGYhkLIEAFGGKGYIVETPDELKSALAESFAARKPAVVNVIID 558
Cdd:cd02009 123 ERlfGTPQGL--DFEH--LAKAYGLEYRRVSSLDELEQALESALAQDGPHVIEVKTD 175
|
|
| TPP_PpyrDC |
cd03371 |
Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of ... |
430-567 |
6.78e-04 |
|
Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of proteins similar to phosphonopyruvate decarboxylase (PpyrDC) proteins. PpyrDC is a homotrimeric enzyme which functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. These proteins require TPP and divalent metal cation cofactors.
Pssm-ID: 239468 [Multi-domain] Cd Length: 188 Bit Score: 41.14 E-value: 6.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9755761 430 GTMG----VGLGyciaAAVASPDRLVVAVEGDSGF----GFSAMeVETLVRYNLavVIIVFNNgGVYggDRRGPEEISGP 501
Cdd:cd03371 48 GSMGhasqIALG----IALARPDRKVVCIDGDGAAlmhmGGLAT-IGGLAPANL--IHIVLNN-GAH--DSVGGQPTVSF 117
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 9755761 502 HkedpapTSFVPNA---GYHKLieafggkgYIVETPDELKSALAESFAARKPAVVNVIIDPFAGAESGR 567
Cdd:cd03371 118 D------VSLPAIAkacGYRAV--------YEVPSLEELVAALAKALAADGPAFIEVKVRPGSRSDLGR 172
|
|
| |
