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Conserved domains on  [gi|1901084650|emb|CAD5322037|]
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unnamed protein product [Arabidopsis thaliana]

Protein Classification

cupin domain-containing protein( domain architecture ID 10531246)

cupin domain-containing protein similar to Thermotoga maritima TM1112 (also known as DUF861)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cupin_3 pfam05899
EutQ-like cupin domain; This entry represents the cupin domain, with a conserved jelly ...
 14-88 4.90e-31

EutQ-like cupin domain; This entry represents the cupin domain, with a conserved jelly roll-like beta-barrel fold capable of homodimerization found in bacteria, plant and fungi. It is present in EutQ family from the eut operon, involved in ethanolamine degradation. EutQ is essential during anoxic growth and has acetate kinase activity. The cupin domain from EutQ does not possess the His residues responsible for metal coordination in other classes of cupins. This domain is also found in (S)-ureidoglycine aminohydrolase (UGlyAH) from E.coli, which is involved in the anaerobic nitrogen utilization via the assimilation of allantoin. It catalyzes the deamination of allantoin to produce S-ureidoglycolate and ammonia from S-ureidoglycine.


:

Pssm-ID: 399116 [Multi-domain]  Cd Length: 74  Bit Score: 104.29  E-value: 4.90e-31
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1901084650 14 LSDLGVMSWPKWSCQPGKYALVFEERETCYLVKGKVKVYPKGSSEfVEFGAGDLVTIPKGLSCTWDVSLFIDKHY 88
Cdd:pfam05899  1 LSPLGVFSWGIWECTPGKFRWTYEEDETCYILSGEVTVTPEGGKT-VTLRAGDLVVLPKGLSGTWDVLETVRKHY 74
 
Name Accession Description Interval E-value
Cupin_3 pfam05899
EutQ-like cupin domain; This entry represents the cupin domain, with a conserved jelly ...
 14-88 4.90e-31

EutQ-like cupin domain; This entry represents the cupin domain, with a conserved jelly roll-like beta-barrel fold capable of homodimerization found in bacteria, plant and fungi. It is present in EutQ family from the eut operon, involved in ethanolamine degradation. EutQ is essential during anoxic growth and has acetate kinase activity. The cupin domain from EutQ does not possess the His residues responsible for metal coordination in other classes of cupins. This domain is also found in (S)-ureidoglycine aminohydrolase (UGlyAH) from E.coli, which is involved in the anaerobic nitrogen utilization via the assimilation of allantoin. It catalyzes the deamination of allantoin to produce S-ureidoglycolate and ammonia from S-ureidoglycine.


Pssm-ID: 399116 [Multi-domain]  Cd Length: 74  Bit Score: 104.29  E-value: 4.90e-31
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1901084650 14 LSDLGVMSWPKWSCQPGKYALVFEERETCYLVKGKVKVYPKGSSEfVEFGAGDLVTIPKGLSCTWDVSLFIDKHY 88
Cdd:pfam05899  1 LSPLGVFSWGIWECTPGKFRWTYEEDETCYILSGEVTVTPEGGKT-VTLRAGDLVVLPKGLSGTWDVLETVRKHY 74
cupin_TM1112-like cd02227
Thermotoga maritima TM1112 and related proteins, cupin domain; This family includes bacterial ...
 21-90 2.91e-30

Thermotoga maritima TM1112 and related proteins, cupin domain; This family includes bacterial and plant proteins homologous to TM1112, a Thermotoga maritima protein of unknown function with a cupin beta barrel domain. TM1112 (also known as DUF861) is a subfamily of RmlC-like cupins with a conserved "jelly roll-like" beta-barrel fold; structures indicate that a monomer is the biologically-relevant form.


Pssm-ID: 380356 [Multi-domain]  Cd Length: 69  Bit Score: 101.89  E-value: 2.91e-30
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1901084650 21 SWPKWSCQPGKYALVFEERETCYLVKGKVKVYPKGSSEfVEFGAGDLVTIPKGLSCTWDVSLFIDKHYKF 90
Cdd:cd02227    1 SWGIWECTPGKFPWNYDEDEFCYILEGEVRVTPEDGEP-VTFKAGDLVVFPAGFSGTWEVLEPVRKHYVF 69
COG3450 COG3450
Predicted enzyme of the cupin superfamily [General function prediction only];
4-90 6.57e-19

Predicted enzyme of the cupin superfamily [General function prediction only];


Pssm-ID: 442673  Cd Length: 108  Bit Score: 74.25  E-value: 6.57e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1901084650   4 VIENNPSSRRLSD---------LGVmswpkWSCQPGKYALVFEERETCYLVKGKVKVYPKGSSEfVEFGAGDLVTIPKGL 74
Cdd:COG3450    18 ILEGDPSARTWNLftspdggvsAGV-----WECTPGKFRWDYDEDEFCYILEGRVTVTDDDGEP-VEFGAGDSFVFPAGF 91

                          90
                  ....*....|....*.
gi 1901084650  75 SCTWDVSLFIDKHYKF 90
Cdd:COG3450    92 KGTWEVLETVRKHYVI 107
 
Name Accession Description Interval E-value
Cupin_3 pfam05899
EutQ-like cupin domain; This entry represents the cupin domain, with a conserved jelly ...
 14-88 4.90e-31

EutQ-like cupin domain; This entry represents the cupin domain, with a conserved jelly roll-like beta-barrel fold capable of homodimerization found in bacteria, plant and fungi. It is present in EutQ family from the eut operon, involved in ethanolamine degradation. EutQ is essential during anoxic growth and has acetate kinase activity. The cupin domain from EutQ does not possess the His residues responsible for metal coordination in other classes of cupins. This domain is also found in (S)-ureidoglycine aminohydrolase (UGlyAH) from E.coli, which is involved in the anaerobic nitrogen utilization via the assimilation of allantoin. It catalyzes the deamination of allantoin to produce S-ureidoglycolate and ammonia from S-ureidoglycine.


Pssm-ID: 399116 [Multi-domain]  Cd Length: 74  Bit Score: 104.29  E-value: 4.90e-31
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1901084650 14 LSDLGVMSWPKWSCQPGKYALVFEERETCYLVKGKVKVYPKGSSEfVEFGAGDLVTIPKGLSCTWDVSLFIDKHY 88
Cdd:pfam05899  1 LSPLGVFSWGIWECTPGKFRWTYEEDETCYILSGEVTVTPEGGKT-VTLRAGDLVVLPKGLSGTWDVLETVRKHY 74
cupin_TM1112-like cd02227
Thermotoga maritima TM1112 and related proteins, cupin domain; This family includes bacterial ...
 21-90 2.91e-30

Thermotoga maritima TM1112 and related proteins, cupin domain; This family includes bacterial and plant proteins homologous to TM1112, a Thermotoga maritima protein of unknown function with a cupin beta barrel domain. TM1112 (also known as DUF861) is a subfamily of RmlC-like cupins with a conserved "jelly roll-like" beta-barrel fold; structures indicate that a monomer is the biologically-relevant form.


Pssm-ID: 380356 [Multi-domain]  Cd Length: 69  Bit Score: 101.89  E-value: 2.91e-30
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1901084650 21 SWPKWSCQPGKYALVFEERETCYLVKGKVKVYPKGSSEfVEFGAGDLVTIPKGLSCTWDVSLFIDKHYKF 90
Cdd:cd02227    1 SWGIWECTPGKFPWNYDEDEFCYILEGEVRVTPEDGEP-VTFKAGDLVVFPAGFSGTWEVLEPVRKHYVF 69
COG3450 COG3450
Predicted enzyme of the cupin superfamily [General function prediction only];
4-90 6.57e-19

Predicted enzyme of the cupin superfamily [General function prediction only];


Pssm-ID: 442673  Cd Length: 108  Bit Score: 74.25  E-value: 6.57e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1901084650   4 VIENNPSSRRLSD---------LGVmswpkWSCQPGKYALVFEERETCYLVKGKVKVYPKGSSEfVEFGAGDLVTIPKGL 74
Cdd:COG3450    18 ILEGDPSARTWNLftspdggvsAGV-----WECTPGKFRWDYDEDEFCYILEGRVTVTDDDGEP-VEFGAGDSFVFPAGF 91

                          90
                  ....*....|....*.
gi 1901084650  75 SCTWDVSLFIDKHYKF 90
Cdd:COG3450    92 KGTWEVLETVRKHYVI 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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