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Conserved domains on  [gi|40039416|emb|CAE98460|]
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unnamed protein product, partial [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DERM super family cl20641
Dermatopontin; Members of this family mediate cell adhesion via cell surface integrin binding. ...
 43-134 3.71e-28

Dermatopontin; Members of this family mediate cell adhesion via cell surface integrin binding. They also induce haemagglutination and aggregation of amebocytes.


The actual alignment was detected with superfamily member pfam14704:

Pssm-ID: 464273  Cd Length: 151  Bit Score: 100.83  E-value: 3.71e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40039416    43 RQGFSYQCPQGQVIVAVRSIFSKKEGsDRQWNYACMPTPQSlGEPTECWW-EEINRAGMEWYQTCSNNGLVAGFQSRYFE 121
Cdd:pfam14704   4 DQPFSFTCPSGQGISGIYSYHSNNKE-DRRWSFTCSDVGGT-SSSTSCSWsGYVNDYDQPFTFTCPDNYYLTGVESEHSN 81

                          90
                  ....*....|...
gi 40039416   122 SVLDREWQFYCCR 134
Cdd:pfam14704  82 SAEDRRWKFQCCR 94
 
Name Accession Description Interval E-value
DERM pfam14704
Dermatopontin; Members of this family mediate cell adhesion via cell surface integrin binding. ...
 43-134 3.71e-28

Dermatopontin; Members of this family mediate cell adhesion via cell surface integrin binding. They also induce haemagglutination and aggregation of amebocytes.


Pssm-ID: 464273  Cd Length: 151  Bit Score: 100.83  E-value: 3.71e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40039416    43 RQGFSYQCPQGQVIVAVRSIFSKKEGsDRQWNYACMPTPQSlGEPTECWW-EEINRAGMEWYQTCSNNGLVAGFQSRYFE 121
Cdd:pfam14704   4 DQPFSFTCPSGQGISGIYSYHSNNKE-DRRWSFTCSDVGGT-SSSTSCSWsGYVNDYDQPFTFTCPDNYYLTGVESEHSN 81

                          90
                  ....*....|...
gi 40039416   122 SVLDREWQFYCCR 134
Cdd:pfam14704  82 SAEDRRWKFQCCR 94
 
Name Accession Description Interval E-value
DERM pfam14704
Dermatopontin; Members of this family mediate cell adhesion via cell surface integrin binding. ...
 43-134 3.71e-28

Dermatopontin; Members of this family mediate cell adhesion via cell surface integrin binding. They also induce haemagglutination and aggregation of amebocytes.


Pssm-ID: 464273  Cd Length: 151  Bit Score: 100.83  E-value: 3.71e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40039416    43 RQGFSYQCPQGQVIVAVRSIFSKKEGsDRQWNYACMPTPQSlGEPTECWW-EEINRAGMEWYQTCSNNGLVAGFQSRYFE 121
Cdd:pfam14704   4 DQPFSFTCPSGQGISGIYSYHSNNKE-DRRWSFTCSDVGGT-SSSTSCSWsGYVNDYDQPFTFTCPDNYYLTGVESEHSN 81

                          90
                  ....*....|...
gi 40039416   122 SVLDREWQFYCCR 134
Cdd:pfam14704  82 SAEDRRWKFQCCR 94
DERM pfam14704
Dermatopontin; Members of this family mediate cell adhesion via cell surface integrin binding. ...
 37-134 1.00e-06

Dermatopontin; Members of this family mediate cell adhesion via cell surface integrin binding. They also induce haemagglutination and aggregation of amebocytes.


Pssm-ID: 464273  Cd Length: 151  Bit Score: 44.98  E-value: 1.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40039416    37 GWVNLNRQGFSYQCPQGQVIVAVRSIFS-KKEgsDRQWNYACMPTPQslGEPTECWWEE-INRAGMEWYQTCSNNGLVAG 114
Cdd:pfam14704  53 GYVNDYDQPFTFTCPDNYYLTGVESEHSnSAE--DRRWKFQCCRING--ATLSNCRTTGyLNSFDGPLDFTAPSGYVITG 128

                          90       100
                  ....*....|....*....|
gi 40039416   115 FQSRYFESVLDREWQFYCCR 134
Cdd:pfam14704 129 VSSYHDNSKEDRRWKFRTCR 148
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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