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Conserved domains on  [gi|40042910|emb|CAF00231|]
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unnamed protein product, partial [Homo sapiens]

Protein Classification

J domain-containing protein( domain architecture ID 10446266)

J domain-containing protein containing a similar domain as DnaJ, a protein that plays crucial roles in protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of Hsp70.

CATH:  1.10.287.110
Gene Ontology:  GO:0006457
PubMed:  35729039|9644977|8016869|15170475
SCOP:  4000605

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 11-73 5.79e-23

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


:

Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 82.91  E-value: 5.79e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYD 73
Cdd:pfam00226  1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
 
Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 11-73 5.79e-23

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 82.91  E-value: 5.79e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYD 73
Cdd:pfam00226  1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 11-73 9.53e-22

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 86.35  E-value: 9.53e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYD 73
Cdd:PRK10767   5 DYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGDKEAEEKFKEIKEAYEVLSDPQKRAAYD 67
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 11-65 1.10e-18

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 71.81  E-value: 1.10e-18
                       10        20        30        40        50
               ....*....|....*....|....*....|....*....|....*....|....*
gi 40042910 11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTD 65
Cdd:cd06257  1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDDPEAEEKFKEINEAYEVLSD 55
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 11-74 2.64e-18

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 76.87  E-value: 2.64e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 40042910    11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDnPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKD-KEAEEKFKEINEAYEVLSDPEKRAQYDQ 63
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 11-79 9.91e-17

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 69.35  E-value: 9.91e-17
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 40042910  11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDKVR*AK 79
Cdd:COG0484   1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDPEAEEKFKEINEAYEVLSDPEKRAAYDRFGHAA 69
DnaJ smart00271
DnaJ molecular chaperone homology domain;
10-65 2.68e-15

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 63.41  E-value: 2.68e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 40042910    10 MDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPR-AAELFHQLSQALEVLTD 65
Cdd:smart00271  1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEeAEEKFKEINEAYEVLSD 57
 
Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 11-73 5.79e-23

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 82.91  E-value: 5.79e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYD 73
Cdd:pfam00226  1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 11-73 9.53e-22

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 86.35  E-value: 9.53e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYD 73
Cdd:PRK10767   5 DYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGDKEAEEKFKEIKEAYEVLSDPQKRAAYD 67
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 9-74 8.51e-21

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 84.02  E-value: 8.51e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 40042910    9 QMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14301   3 QRDYYEVLGVSRDASEDEIKKAYRKLALQYHPDRNPDNPEAEQKFKEAAEAYEVLRDAEKRARYDR 68
PRK14279 PRK14279
molecular chaperone DnaJ;
5-76 4.44e-20

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 82.09  E-value: 4.44e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 40042910    5 KELLQMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDKVR 76
Cdd:PRK14279   4 REWVEKDFYKELGVSSDASAEEIKKAYRKLARELHPDANPGDPAAEERFKAVSEAHDVLSDPAKRKEYDETR 75
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 11-74 4.53e-19

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 79.04  E-value: 4.53e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14294   5 DYYEILGVTRDASEEEIKKSYRKLAMKYHPDRNPGDKEAEELFKEAAEAYEVLSDPKKRGIYDQ 68
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 11-65 1.10e-18

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 71.81  E-value: 1.10e-18
                       10        20        30        40        50
               ....*....|....*....|....*....|....*....|....*....|....*
gi 40042910 11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTD 65
Cdd:cd06257  1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDDPEAEEKFKEINEAYEVLSD 55
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 11-74 2.64e-18

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 76.87  E-value: 2.64e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 40042910    11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDnPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:TIGR02349   1 DYYEILGVSKDASEEEIKKAYRKLAKKYHPDRNKD-KEAEEKFKEINEAYEVLSDPEKRAQYDQ 63
PRK14295 PRK14295
molecular chaperone DnaJ;
4-76 3.88e-18

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 76.81  E-value: 3.88e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 40042910    4 TKELLQMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDKVR 76
Cdd:PRK14295   3 TKDYIEKDYYKVLGVPKDATEAEIKKAYRKLAREYHPDANKGDAKAEERFKEISEAYDVLSDEKKRKEYDEAR 75
PRK14297 PRK14297
molecular chaperone DnaJ;
11-74 7.51e-18

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 75.98  E-value: 7.51e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14297   5 DYYEVLGLEKGASDDEIKKAFRKLAIKYHPDKNKGNKEAEEKFKEINEAYQVLSDPQKKAQYDQ 68
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 10-74 8.72e-18

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 75.65  E-value: 8.72e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 40042910   10 MDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14284   1 MDYYTILGVSKTASPEEIKKAYRKLAVKYHPDKNPGDAEAEKRFKEVSEAYEVLSDAQKRESYDR 65
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 11-73 9.28e-18

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 75.47  E-value: 9.28e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDnPRAAELFHQLSQALEVLTDAAARAAYD 73
Cdd:PRK14278   4 DYYGLLGVSRNASDAEIKRAYRKLARELHPDVNPD-EEAQEKFKEISVAYEVLSDPEKRRIVD 65
PRK14289 PRK14289
molecular chaperone DnaJ;
11-74 1.09e-17

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 75.25  E-value: 1.09e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14289   6 DYYEVLGVSKTATVDEIKKAYRKKAIQYHPDKNPGDKEAEEKFKEAAEAYDVLSDPDKRSRYDQ 69
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 1-74 3.65e-17

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 74.11  E-value: 3.65e-17
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 40042910    1 MAVTKellqmDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDnPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14298   1 MATTR-----DYYEILGLSKDASVEDIKKAYRKLAMKYHPDKNKE-PDAEEKFKEISEAYAVLSDAEKRAQYDR 68
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 11-74 5.24e-17

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 73.68  E-value: 5.24e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14277   6 DYYEILGVDRNATEEEIKKAYRRLAKKYHPDLNPGDKEAEQKFKEINEAYEILSDPQKRAQYDQ 69
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 11-74 9.10e-17

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 72.92  E-value: 9.10e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14281   4 DYYEVLGVSRSADKDEIKKAYRKLALKYHPDKNPDNKEAEEHFKEVNEAYEVLSNDDKRRRYDQ 67
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 11-79 9.91e-17

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 69.35  E-value: 9.91e-17
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 40042910  11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDKVR*AK 79
Cdd:COG0484   1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDPEAEEKFKEINEAYEVLSDPEKRAAYDRFGHAA 69
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 10-74 1.35e-16

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 72.23  E-value: 1.35e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 40042910   10 MDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDnPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14292   2 MDYYELLGVSRTASADEIKSAYRKLALKYHPDRNKE-KGAAEKFAQINEAYAVLSDAEKRAHYDR 65
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 8-74 1.54e-16

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 72.33  E-value: 1.54e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 40042910    8 LQMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14285   1 MKRDYYEILGLSKGASKDEIKKAYRKIAIKYHPDKNKGNKEAESIFKEATEAYEVLIDDNKRAQYDR 67
DnaJ smart00271
DnaJ molecular chaperone homology domain;
10-65 2.68e-15

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 63.41  E-value: 2.68e-15
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 40042910    10 MDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPR-AAELFHQLSQALEVLTD 65
Cdd:smart00271  1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEeAEEKFKEINEAYEVLSD 57
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 11-74 3.70e-15

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 68.42  E-value: 3.70e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDN-PRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14290   4 DYYKILGVDRNASQEDIKKAFRELAKKWHPDLHPGNkAEAEEKFKEISEAYEVLSDPQKRRQYDQ 68
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 13-78 4.20e-15

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 68.09  E-value: 4.20e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 40042910   13 YALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDKVR*A 78
Cdd:PRK14286   7 YDILGVSKSANDEEIKSAYRKLAIKYHPDKNKGNKESEEKFKEATEAYEILRDPKKRQAYDQFGKA 72
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 9-74 7.45e-15

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 67.42  E-value: 7.45e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 40042910    9 QMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDnPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14276   3 NTEYYDRLGVSKDASQDEIKKAYRKLSKKYHPDINKE-PGAEEKYKEVQEAYETLSDPQKRAAYDQ 67
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 11-74 1.74e-14

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 66.39  E-value: 1.74e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNpDNPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14283   6 DYYEVLGVDRNADKKEIKKAYRKLARKYHPDVS-EEEGAEEKFKEISEAYAVLSDDEKRQRYDQ 68
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 11-74 4.05e-14

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 65.20  E-value: 4.05e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAE-LFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14282   5 DYYEILGVSRNATQEEIKRAYKRLVKEWHPDRHPENRKEAEqKFKEIQEAYEVLSDPQKRAMYDR 69
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 9-74 6.25e-14

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 64.79  E-value: 6.25e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 40042910    9 QMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPdNPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14291   2 KKDYYEILGVSRNATQEEIKKAYRRLARKYHPDFNK-NPEAEEKFKEINEAYQVLSDPEKRKLYDQ 66
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
11-82 6.65e-14

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 60.89  E-value: 6.65e-14
                       10        20        30        40        50        60        70
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 40042910 11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPR-AAELFHQLSQALEVLTDAAARAAYDKVR*AKKQA 82
Cdd:COG2214  6 DHYAVLGVPPDASLEEIRQAYRRLAKLLHPDRGGELKAlAEELFQRLNEAYEVLSDPERRAEYDRELGQSGKG 78
PRK14280 PRK14280
molecular chaperone DnaJ;
11-74 2.56e-13

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 63.20  E-value: 2.56e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDnPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14280   5 DYYEVLGVSKSASKDEIKKAYRKLSKKYHPDINKE-EGADEKFKEISEAYEVLSDDQKRAQYDQ 67
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
 11-71 5.13e-13

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 57.70  E-value: 5.13e-13
                       10        20        30        40        50        60
               ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 40042910 11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAA 71
Cdd:COG5407  1 DPYEVLGVAKTASADEIKKAYRKLAKKYHPDRNKGDPKAEERFKEINEAYELLSDAEKRAR 61
PRK14293 PRK14293
molecular chaperone DnaJ;
11-74 1.73e-12

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 60.77  E-value: 1.73e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDnPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14293   4 DYYEILGVSRDADKDELKRAYRRLARKYHPDVNKE-PGAEDRFKEINRAYEVLSDPETRARYDQ 66
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 11-74 1.09e-11

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 58.41  E-value: 1.09e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDnPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14299   5 DYYAILGVPKNASQDEIKKAFKKLARKYHPDVNKS-PGAEEKFKEINEAYTVLSDPEKRRIYDT 67
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 12-74 1.59e-11

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 58.29  E-value: 1.59e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 40042910   12 LYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDnpraAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PTZ00037  30 LYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKGGD----PEKFKEISRAYEVLSDPEKRKIYDE 88
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 11-74 1.17e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 55.79  E-value: 1.17e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDnPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14287   5 DYYEVLGVDRNASVDEVKKAYRKLARKYHPDVNKA-PDAEDKFKEVKEAYDTLSDPQKKAHYDQ 67
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 11-74 1.24e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 55.72  E-value: 1.24e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDnPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14296   5 DYYEVLGVSKTASEQEIRQAYRKLAKQYHPDLNKS-PDAHDKMVEINEAADVLLDKDKRKQYDQ 67
PRK10266 PRK10266
curved DNA-binding protein;
11-76 1.35e-10

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 55.21  E-value: 1.35e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRQKALSCHPD--KNPDnprAAELFHQLSQALEVLTDAAARAAYDKVR 76
Cdd:PRK10266   5 DYYAIMGVKPTDDLKTIKTAYRRLARKYHPDvsKEPD---AEARFKEVAEAWEVLSDEQRRAEYDQLW 69
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 8-74 4.92e-10

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 53.86  E-value: 4.92e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 40042910    8 LQMDLYALLGIEEKAADKEVKKAYRQKALSCHPDkNPDNPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14300   1 MSQDYYQILGVSKTASQADLKKAYLKLAKQYHPD-TTDAKDAEKKFKEINAAYDVLKDEQKRAAYDR 66
PRK14288 PRK14288
molecular chaperone DnaJ;
8-74 1.22e-08

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 50.07  E-value: 1.22e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 40042910    8 LQMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDK 74
Cdd:PRK14288   1 MELSYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGDKEAEEKFKLINEAYGVLSDEKKRALYDR 67
djlA PRK09430
co-chaperone DjlA;
11-42 1.79e-05

co-chaperone DjlA;


Pssm-ID: 236512 [Multi-domain]  Cd Length: 267  Bit Score: 40.95  E-value: 1.79e-05
                         10        20        30
                 ....*....|....*....|....*....|...
gi 40042910   11 DLYALLGIEEKAADKEVKKAYRqKALS-CHPDK 42
Cdd:PRK09430 201 DAYKVLGVSESDDDQEIKRAYR-KLMSeHHPDK 232
ZUO1 COG5269
Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / ...
 5-75 4.36e-05

Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227594 [Multi-domain]  Cd Length: 379  Bit Score: 40.02  E-value: 4.36e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 40042910   5 KELLQMDLYALLGIEE---KAADKEVKKAYRQKALSCHPDKNP--DNPRAAELFHQLSQALEVLTDAAARAAYDKV 75
Cdd:COG5269  38 KNWKKVDLYALLGLSKyrtKAIPPQILKAHKKKVYKYHPDKTAagGNKGCDEFFKLIQKAREVLGDRKLRLQYDSN 113
DjlA COG1076
DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];
9-86 6.27e-05

DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440694 [Multi-domain]  Cd Length: 75  Bit Score: 37.47  E-value: 6.27e-05
                       10        20        30        40        50        60        70        80
               ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 40042910  9 QMDLYALLGIEEKAADKEVKKAYRQKALSCHPDK--NPDNPRAAELFHQLSQALevltdaaaRAAYDKVR*AKKQAAERT 86
Cdd:COG1076  3 LDDAFELLGLPPDADDAELKRAYRKLQREHHPDRlaAGLPEEEQRLALQKAAAI--------NEAYETLKDPRGIDLAAP 74
PHA03102 PHA03102
Small T antigen; Reviewed
 1-52 1.95e-03

Small T antigen; Reviewed


Pssm-ID: 222986 [Multi-domain]  Cd Length: 153  Bit Score: 34.65  E-value: 1.95e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 40042910    1 MAVTKELLQmdlyaLLGIEEKAADKE--VKKAYRQKALSCHPDKNPDNPRAAEL 52
Cdd:PHA03102   1 REESKELMD-----LLGLPRSAWGNLplMRKAYLRKCLEFHPDKGGDEEKMKEL 49
PHA02624 PHA02624
large T antigen; Provisional
 5-52 9.50e-03

large T antigen; Provisional


Pssm-ID: 222912 [Multi-domain]  Cd Length: 647  Bit Score: 33.42  E-value: 9.50e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 40042910    5 KELLQmdlyaLLGIEEKAADKE--VKKAYRQKALSCHPDKNPDNPRAAEL 52
Cdd:PHA02624  11 KELMD-----LLGLPMAAWGNLplMRKAYLRKCKEYHPDKGGDEEKMKRL 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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