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Conserved domains on  [gi|2039003223|emb|CAG6330573|]
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transcriptional regulator [Streptococcus pneumoniae]

Protein Classification

PadR family transcriptional regulator( domain architecture ID 11447737)

PadR family transcriptional regulator similar to the phenolic acid decarboxylation repressor, which is a transcription factor that represses genes associated with the phenolic acid stress response in gram-positive bacteria

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
10-96 4.86e-22

DNA-binding transcriptional regulator, PadR family [Transcription];


:

Pssm-ID: 441301  Cd Length: 102  Bit Score: 82.68  E-value: 4.86e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2039003223  10 IEFLILAVLEQGDSYGYEISQTIKLIAN----IKESTLYPILKKLEGNSFLTTYSREF-QGRMRKYYSLTNGGIEQLLTL 84
Cdd:COG1695    10 LELLILALLAEGPMYGYEIIKELEERSGgfwkVSEGTLYPALKRLEKEGLVESEWEESeGGPRRKYYRLTEAGREELAEW 89
                          90
                  ....*....|..
gi 2039003223  85 KDEWTLYTDTIN 96
Cdd:COG1695    90 LEEWEKLAEALE 101
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
10-96 4.86e-22

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 82.68  E-value: 4.86e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2039003223  10 IEFLILAVLEQGDSYGYEISQTIKLIAN----IKESTLYPILKKLEGNSFLTTYSREF-QGRMRKYYSLTNGGIEQLLTL 84
Cdd:COG1695    10 LELLILALLAEGPMYGYEIIKELEERSGgfwkVSEGTLYPALKRLEKEGLVESEWEESeGGPRRKYYRLTEAGREELAEW 89
                          90
                  ....*....|..
gi 2039003223  85 KDEWTLYTDTIN 96
Cdd:COG1695    90 LEEWEKLAEALE 101
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
14-81 1.56e-14

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 62.65  E-value: 1.56e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2039003223  14 ILAVLEQGDSYGYEISQTIKLIAN----IKESTLYPILKKLEGNSFLTTY-SREFQGRMRKYYSLTNGGIEQL 81
Cdd:pfam03551   1 VLAVLGEQPRYGYEIIKELEELSGgfwrPSEGTLYPILKRLEKEGLVESEwVDSGGGPPRKYYRLTDAGRREL 73
lstR PRK09416
PadR family transcriptional regulator;
13-101 4.63e-06

PadR family transcriptional regulator;


Pssm-ID: 181836  Cd Length: 135  Bit Score: 42.47  E-value: 4.63e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2039003223  13 LILAVLEQgDSYGYEISQTI--KLIANIK--ESTLYPILKKLEGNSFLTTysrEFQGRMRKYYSLTNGGIEQLLTLKDEW 88
Cdd:PRK09416   47 AILQLLMN-EKTGYELLQLLrqRGILTFEgnEGSLYTLLHRLEQNRFIQS---SWDHEGAKYYQLTDKGNKMLRKAEKNA 122
                          90
                  ....*....|...
gi 2039003223  89 TLYTDTINGIIEG 101
Cdd:PRK09416  123 TKARFILKGLVQE 135
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
10-96 4.86e-22

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 82.68  E-value: 4.86e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2039003223  10 IEFLILAVLEQGDSYGYEISQTIKLIAN----IKESTLYPILKKLEGNSFLTTYSREF-QGRMRKYYSLTNGGIEQLLTL 84
Cdd:COG1695    10 LELLILALLAEGPMYGYEIIKELEERSGgfwkVSEGTLYPALKRLEKEGLVESEWEESeGGPRRKYYRLTEAGREELAEW 89
                          90
                  ....*....|..
gi 2039003223  85 KDEWTLYTDTIN 96
Cdd:COG1695    90 LEEWEKLAEALE 101
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
14-81 1.56e-14

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 62.65  E-value: 1.56e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2039003223  14 ILAVLEQGDSYGYEISQTIKLIAN----IKESTLYPILKKLEGNSFLTTY-SREFQGRMRKYYSLTNGGIEQL 81
Cdd:pfam03551   1 VLAVLGEQPRYGYEIIKELEELSGgfwrPSEGTLYPILKRLEKEGLVESEwVDSGGGPPRKYYRLTDAGRREL 73
lstR PRK09416
PadR family transcriptional regulator;
13-101 4.63e-06

PadR family transcriptional regulator;


Pssm-ID: 181836  Cd Length: 135  Bit Score: 42.47  E-value: 4.63e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2039003223  13 LILAVLEQgDSYGYEISQTI--KLIANIK--ESTLYPILKKLEGNSFLTTysrEFQGRMRKYYSLTNGGIEQLLTLKDEW 88
Cdd:PRK09416   47 AILQLLMN-EKTGYELLQLLrqRGILTFEgnEGSLYTLLHRLEQNRFIQS---SWDHEGAKYYQLTDKGNKMLRKAEKNA 122
                          90
                  ....*....|...
gi 2039003223  89 TLYTDTINGIIEG 101
Cdd:PRK09416  123 TKARFILKGLVQE 135
COG1777 COG1777
Predicted transcriptional regulator, ArsR family [Transcription];
14-90 3.05e-04

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441383  Cd Length: 113  Bit Score: 36.94  E-value: 3.05e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2039003223  14 ILAVLEQGDSYGYEISQTIkliaNIKESTLYPILKKLEGNSFLTTYSREFQ-GRMRKYYSLTNGGIEQLLTLKDEWTL 90
Cdd:COG1777    22 ILALLSEEPAYVSELAREL----GVSRQAVYKHLRKLEEAGLVESYREGREdGRARKYYRLSAFRLEVTLTPDLFARL 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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