|
Name |
Accession |
Description |
Interval |
E-value |
| SerC |
COG1932 |
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and ... |
1-353 |
0e+00 |
|
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and metabolism]; Phosphoserine aminotransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 441535 Cd Length: 358 Bit Score: 541.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 1 MRLHNFSAGPSILPKEVMHQAAEAVKELDGSKLSLIEISHRSKAFIDIMDEACERALRLTGLeGKGYKAIFLQGGASLQF 80
Cdd:COG1932 1 MRVYNFSAGPAKLPEEVLEQAQAELLDWNGSGMSVMEMSHRSKPFKAIVEEAEADLRELLGI-PDGYEVLFLQGGATAQF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 81 LMAAYNLLEN--KAGYLNTGTWSDKAIKEAKLFGEVIEIASSKDQNYNHIPK--DYSIPSGLDYLHLTTNNTIFGTQFKS 156
Cdd:COG1932 80 AMVPMNLLRGgkKADYLVTGEWSKKAIKEAKKYGEVNVVASSEDDNFGYIPKpeEWQLSPDADYVHYTSNETITGVEFHE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 157 IPET-DAPLVADMSSDIFSRTFDYSKFDLFYAGAQKNMGPAGTTLVIVKESLLGKVSRAIPSMMSYEVHASKDSMFNTPP 235
Cdd:COG1932 160 LPDVgDVPLVADMSSDILSRPVDVSKFGLIYAGAQKNIGPAGLTVVIVRPDLLGRAERAIPSMLDYKTHADNDSMYNTPP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 236 VFAVYTSMLNMRWIESQGGIRSLGDKNSVKSTLLYGEIDRNSLFEGFAAKEDRSDMNATFNLKDTAYTEAFDSLCQTAGI 315
Cdd:COG1932 240 TFAIYLAGLVLKWLKEQGGLAAMEKRNAEKAALLYDWIDASDFYTNPVDPEDRSRMNVTFDLADEELDAAFLAEAKAAGL 319
|
330 340 350
....*....|....*....|....*....|....*...
gi 2474877695 316 SGLKGHRSVGGYRASMYNAMSIESVEILVDCMQILEKK 353
Cdd:COG1932 320 VGLKGHRSVGGMRASIYNAMPLEGVEALVDFMDEFERR 357
|
|
| PRK05355 |
PRK05355 |
3-phosphoserine/phosphohydroxythreonine transaminase; |
1-353 |
0e+00 |
|
3-phosphoserine/phosphohydroxythreonine transaminase;
Pssm-ID: 235428 Cd Length: 360 Bit Score: 540.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 1 MRLHNFSAGPSILPKEVMHQAAEAVKELDGSKLSLIEISHRSKAFIDIMDEACERALRLTGLeGKGYKAIFLQGGASLQF 80
Cdd:PRK05355 2 MRVYNFSAGPAMLPEEVLEQAQQELLDWNGSGMSVMEISHRSKEFEAVAEEAEADLRELLNI-PDNYKVLFLQGGASLQF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 81 LMAAYNLLEN--KAGYLNTGTWSDKAIKEAKLFGEVIEIASSKDQNYNHIPK--DYSIPSGLDYLHLTTNNTIFGTQFKS 156
Cdd:PRK05355 81 AMVPMNLLGGgkKADYVDTGSWSKKAIKEAKKYGEVNVAASSEDDGFTYIPPldEWQLSDDAAYVHYTSNETIDGTEFHE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 157 IPET-DAPLVADMSSDIFSRTFDYSKFDLFYAGAQKNMGPAGTTLVIVKESLLGKVSRAIPSMMSYEVHASKDSMFNTPP 235
Cdd:PRK05355 161 LPDTgDVPLVADMSSDILSRPIDVSKFGLIYAGAQKNIGPAGLTIVIVREDLLGRALPSIPSMLDYKTHADNDSMYNTPP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 236 VFAVYTSMLNMRWIESQGGIRSLGDKNSVKSTLLYGEIDRNSLFEGFAAKEDRSDMNATFNLKDTAYTEAFDSLCQTAGI 315
Cdd:PRK05355 241 TFAIYLAGLVFKWLKEQGGVAAMEKRNQEKAALLYDAIDSSDFYRNPVAPEDRSRMNVPFTLADEELDKKFLAEAKAAGL 320
|
330 340 350
....*....|....*....|....*....|....*...
gi 2474877695 316 SGLKGHRSVGGYRASMYNAMSIESVEILVDCMQILEKK 353
Cdd:PRK05355 321 VGLKGHRSVGGMRASIYNAMPLEGVQALVDFMKEFERR 358
|
|
| PSAT_like |
cd00611 |
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP) ... |
4-352 |
1.07e-151 |
|
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as a dimer and catalyzes the conversion of phosphohydroxypyruvate to phosphoserine.
Pssm-ID: 99736 [Multi-domain] Cd Length: 355 Bit Score: 430.95 E-value: 1.07e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 4 HNFSAGPSILPKEVMHQAAEAVKELDGSKLSLIEISHRSKAFIDIMDEACERALRLTGLEgKGYKAIFLQGGASLQFLMA 83
Cdd:cd00611 1 INFSAGPAALPEEVLEQAQKELLDFNGLGMSVMEMSHRSKDFEAIVNEAESDLRELLNIP-DNYKVLFLQGGATGQFAAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 84 AYNLL--ENKAGYLNTGTWSDKAIKEAKLFGEVIEIASSKD-QNYNHIPKDYSIP--SGLDYLHLTTNNTIFGTQFKSIP 158
Cdd:cd00611 80 PLNLLgdKGTADYVVTGAWSAKAAKEAKRYGGVVVIVAAKEeGKYTKIPDVETWDlaPDAAYVHYCSNETIHGVEFDEVP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 159 ET-DAPLVADMSSDIFSRTFDYSKFDLFYAGAQKNMGPAGTTLVIVKESLLGKVSRAIPSMMSYEVHASKDSMFNTPPVF 237
Cdd:cd00611 160 DTgGVPLVADMSSNILSRPIDVSKFGVIYAGAQKNLGPAGVTVVIVRKDLLGKARKITPSMLNYKTHADNNSLYNTPPTF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 238 AVYTSMLNMRWIESQGGIRSLGDKNSVKSTLLYGEIDRNS-LFEGFAAKEDRSDMNATFNLKDTAYTEAFDSLCQTAGIS 316
Cdd:cd00611 240 AIYMMGLVLKWLKEQGGVEAMEKRNRQKAQLLYDTIDNSNgFYRGPVDKRARSRMNVPFRLGKEELEKEFLKEAEAAGMI 319
|
330 340 350
....*....|....*....|....*....|....*.
gi 2474877695 317 GLKGHRSVGGYRASMYNAMSIESVEILVDCMQILEK 352
Cdd:cd00611 320 GLKGHRSVGGIRASIYNALSLEGVQALADFMKEFQK 355
|
|
| serC_1 |
TIGR01364 |
phosphoserine aminotransferase; This model represents the common form of the phosphoserine ... |
11-353 |
3.22e-141 |
|
phosphoserine aminotransferase; This model represents the common form of the phosphoserine aminotransferase SerC. The phosphoserine aminotransferase of the archaeon Methanosarcina barkeri and putative phosphoserine aminotransferase of Mycobacterium tuberculosis are represented by separate models. All are members of the class V aminotransferases (pfam00266). [Amino acid biosynthesis, Serine family]
Pssm-ID: 130431 Cd Length: 349 Bit Score: 403.97 E-value: 3.22e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 11 SILPKEVMHQAAEAVKELDGSKLSLIEISHRSKAFIDIMDEAcERALR-LTGLEgKGYKAIFLQGGASLQFLMAAYNLLE 89
Cdd:TIGR01364 1 AALPEEVLEQAQKELLNFNGTGMSVMEISHRSKEFEAVANEA-ESDLReLLNIP-DNYEVLFLQGGATGQFAAVPLNLLA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 90 N--KAGYLNTGTWSDKAIKEAKLFGEVIEIASSKDQNYNHIP--KDYSIPSGLDYLHLTTNNTIFGTQFKSIPE-TDAPL 164
Cdd:TIGR01364 79 EgkVADYIVTGAWSKKAAKEAKKYGVVNVVASGKEGNYTKIPdpSTWEISEDAAYVHYCANETIHGVEFRELPDvKNAPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 165 VADMSSDIFSRTFDYSKFDLFYAGAQKNMGPAGTTLVIVKESLLGKVSRAIPSMMSYEVHASKDSMFNTPPVFAVYTSML 244
Cdd:TIGR01364 159 VADMSSNILSRPIDVSKFGLIYAGAQKNIGPAGLTVVIVRKDLLGRASRITPSMLNYKIHAENDSMYNTPPTFAIYVSGL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 245 NMRWIESQGGIRSLGDKNSVKSTLLYGEIDRNS-LFEGFAAKEDRSDMNATFNLKDTAYTEAFDSLCQTAGISGLKGHRS 323
Cdd:TIGR01364 239 VFKWLKEQGGVKAIEKRNQAKAQLLYDTIDNSNgFYRNPVDPRNRSRMNVVFTLGNEELEKRFLKEAEERGLVSLKGHRS 318
|
330 340 350
....*....|....*....|....*....|
gi 2474877695 324 VGGYRASMYNAMSIESVEILVDCMQILEKK 353
Cdd:TIGR01364 319 VGGMRASIYNAMPLEGVQALVDFMKEFQKK 348
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
5-343 |
5.49e-30 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 117.73 E-value: 5.49e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 5 NFSAGPSILPKEVMHQAAEAVKELDGSKLSliEISHRSKAFIDIMDEACERALRLTGLEGKgYKAIFLQGGASlQFLMAA 84
Cdd:pfam00266 3 LDSAATTQKPQEVLDAIQEYYTDYNGNVHR--GVHTLGKEATQAYEEAREKVAEFINAPSN-DEIIFTSGTTE-AINLVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 85 YNLLEN-KAG----YLNTGTWSDK-AIKEAKLFG--EVIEIASSKDQNYNHIPKDYSIPSGLDYLHLTTNNTIFGTQF-- 154
Cdd:pfam00266 79 LSLGRSlKPGdeivITEMEHHANLvPWQELAKRTgaRVRVLPLDEDGLLDLDELEKLITPKTKLVAITHVSNVTGTIQpv 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 155 ----KSIPETDAPLVADMSSDIFSRTFDYSKF--DLFYAGAQKNMGPAGTTLVIVKESLLGKVS--------RAIPSmMS 220
Cdd:pfam00266 159 peigKLAHQYGALVLVDAAQAIGHRPIDVQKLgvDFLAFSGHKLYGPTGIGVLYGRRDLLEKMPpllggggmIETVS-LQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 221 YEVHASKDSMFN--TPPVFAVYTSMLNMRWIESqGGIRSLGDKNSVKSTLLYGEIDRNSLFEGFAAKEDRSDMNATFNLK 298
Cdd:pfam00266 238 ESTFADAPWKFEagTPNIAGIIGLGAALEYLSE-IGLEAIEKHEHELAQYLYERLLSLPGIRLYGPERRASIISFNFKGV 316
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 2474877695 299 DTAYTEafdSLCQTAGISGLKGHRSV----------GGYRASMYNAMSIESVEIL 343
Cdd:pfam00266 317 HPHDVA---TLLDESGIAVRSGHHCAqplmvrlglgGTVRASFYIYNTQEDVDRL 368
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| SerC |
COG1932 |
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and ... |
1-353 |
0e+00 |
|
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and metabolism]; Phosphoserine aminotransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 441535 Cd Length: 358 Bit Score: 541.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 1 MRLHNFSAGPSILPKEVMHQAAEAVKELDGSKLSLIEISHRSKAFIDIMDEACERALRLTGLeGKGYKAIFLQGGASLQF 80
Cdd:COG1932 1 MRVYNFSAGPAKLPEEVLEQAQAELLDWNGSGMSVMEMSHRSKPFKAIVEEAEADLRELLGI-PDGYEVLFLQGGATAQF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 81 LMAAYNLLEN--KAGYLNTGTWSDKAIKEAKLFGEVIEIASSKDQNYNHIPK--DYSIPSGLDYLHLTTNNTIFGTQFKS 156
Cdd:COG1932 80 AMVPMNLLRGgkKADYLVTGEWSKKAIKEAKKYGEVNVVASSEDDNFGYIPKpeEWQLSPDADYVHYTSNETITGVEFHE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 157 IPET-DAPLVADMSSDIFSRTFDYSKFDLFYAGAQKNMGPAGTTLVIVKESLLGKVSRAIPSMMSYEVHASKDSMFNTPP 235
Cdd:COG1932 160 LPDVgDVPLVADMSSDILSRPVDVSKFGLIYAGAQKNIGPAGLTVVIVRPDLLGRAERAIPSMLDYKTHADNDSMYNTPP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 236 VFAVYTSMLNMRWIESQGGIRSLGDKNSVKSTLLYGEIDRNSLFEGFAAKEDRSDMNATFNLKDTAYTEAFDSLCQTAGI 315
Cdd:COG1932 240 TFAIYLAGLVLKWLKEQGGLAAMEKRNAEKAALLYDWIDASDFYTNPVDPEDRSRMNVTFDLADEELDAAFLAEAKAAGL 319
|
330 340 350
....*....|....*....|....*....|....*...
gi 2474877695 316 SGLKGHRSVGGYRASMYNAMSIESVEILVDCMQILEKK 353
Cdd:COG1932 320 VGLKGHRSVGGMRASIYNAMPLEGVEALVDFMDEFERR 357
|
|
| PRK05355 |
PRK05355 |
3-phosphoserine/phosphohydroxythreonine transaminase; |
1-353 |
0e+00 |
|
3-phosphoserine/phosphohydroxythreonine transaminase;
Pssm-ID: 235428 Cd Length: 360 Bit Score: 540.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 1 MRLHNFSAGPSILPKEVMHQAAEAVKELDGSKLSLIEISHRSKAFIDIMDEACERALRLTGLeGKGYKAIFLQGGASLQF 80
Cdd:PRK05355 2 MRVYNFSAGPAMLPEEVLEQAQQELLDWNGSGMSVMEISHRSKEFEAVAEEAEADLRELLNI-PDNYKVLFLQGGASLQF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 81 LMAAYNLLEN--KAGYLNTGTWSDKAIKEAKLFGEVIEIASSKDQNYNHIPK--DYSIPSGLDYLHLTTNNTIFGTQFKS 156
Cdd:PRK05355 81 AMVPMNLLGGgkKADYVDTGSWSKKAIKEAKKYGEVNVAASSEDDGFTYIPPldEWQLSDDAAYVHYTSNETIDGTEFHE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 157 IPET-DAPLVADMSSDIFSRTFDYSKFDLFYAGAQKNMGPAGTTLVIVKESLLGKVSRAIPSMMSYEVHASKDSMFNTPP 235
Cdd:PRK05355 161 LPDTgDVPLVADMSSDILSRPIDVSKFGLIYAGAQKNIGPAGLTIVIVREDLLGRALPSIPSMLDYKTHADNDSMYNTPP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 236 VFAVYTSMLNMRWIESQGGIRSLGDKNSVKSTLLYGEIDRNSLFEGFAAKEDRSDMNATFNLKDTAYTEAFDSLCQTAGI 315
Cdd:PRK05355 241 TFAIYLAGLVFKWLKEQGGVAAMEKRNQEKAALLYDAIDSSDFYRNPVAPEDRSRMNVPFTLADEELDKKFLAEAKAAGL 320
|
330 340 350
....*....|....*....|....*....|....*...
gi 2474877695 316 SGLKGHRSVGGYRASMYNAMSIESVEILVDCMQILEKK 353
Cdd:PRK05355 321 VGLKGHRSVGGMRASIYNAMPLEGVQALVDFMKEFERR 358
|
|
| PSAT_like |
cd00611 |
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP) ... |
4-352 |
1.07e-151 |
|
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as a dimer and catalyzes the conversion of phosphohydroxypyruvate to phosphoserine.
Pssm-ID: 99736 [Multi-domain] Cd Length: 355 Bit Score: 430.95 E-value: 1.07e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 4 HNFSAGPSILPKEVMHQAAEAVKELDGSKLSLIEISHRSKAFIDIMDEACERALRLTGLEgKGYKAIFLQGGASLQFLMA 83
Cdd:cd00611 1 INFSAGPAALPEEVLEQAQKELLDFNGLGMSVMEMSHRSKDFEAIVNEAESDLRELLNIP-DNYKVLFLQGGATGQFAAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 84 AYNLL--ENKAGYLNTGTWSDKAIKEAKLFGEVIEIASSKD-QNYNHIPKDYSIP--SGLDYLHLTTNNTIFGTQFKSIP 158
Cdd:cd00611 80 PLNLLgdKGTADYVVTGAWSAKAAKEAKRYGGVVVIVAAKEeGKYTKIPDVETWDlaPDAAYVHYCSNETIHGVEFDEVP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 159 ET-DAPLVADMSSDIFSRTFDYSKFDLFYAGAQKNMGPAGTTLVIVKESLLGKVSRAIPSMMSYEVHASKDSMFNTPPVF 237
Cdd:cd00611 160 DTgGVPLVADMSSNILSRPIDVSKFGVIYAGAQKNLGPAGVTVVIVRKDLLGKARKITPSMLNYKTHADNNSLYNTPPTF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 238 AVYTSMLNMRWIESQGGIRSLGDKNSVKSTLLYGEIDRNS-LFEGFAAKEDRSDMNATFNLKDTAYTEAFDSLCQTAGIS 316
Cdd:cd00611 240 AIYMMGLVLKWLKEQGGVEAMEKRNRQKAQLLYDTIDNSNgFYRGPVDKRARSRMNVPFRLGKEELEKEFLKEAEAAGMI 319
|
330 340 350
....*....|....*....|....*....|....*.
gi 2474877695 317 GLKGHRSVGGYRASMYNAMSIESVEILVDCMQILEK 352
Cdd:cd00611 320 GLKGHRSVGGIRASIYNALSLEGVQALADFMKEFQK 355
|
|
| serC_1 |
TIGR01364 |
phosphoserine aminotransferase; This model represents the common form of the phosphoserine ... |
11-353 |
3.22e-141 |
|
phosphoserine aminotransferase; This model represents the common form of the phosphoserine aminotransferase SerC. The phosphoserine aminotransferase of the archaeon Methanosarcina barkeri and putative phosphoserine aminotransferase of Mycobacterium tuberculosis are represented by separate models. All are members of the class V aminotransferases (pfam00266). [Amino acid biosynthesis, Serine family]
Pssm-ID: 130431 Cd Length: 349 Bit Score: 403.97 E-value: 3.22e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 11 SILPKEVMHQAAEAVKELDGSKLSLIEISHRSKAFIDIMDEAcERALR-LTGLEgKGYKAIFLQGGASLQFLMAAYNLLE 89
Cdd:TIGR01364 1 AALPEEVLEQAQKELLNFNGTGMSVMEISHRSKEFEAVANEA-ESDLReLLNIP-DNYEVLFLQGGATGQFAAVPLNLLA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 90 N--KAGYLNTGTWSDKAIKEAKLFGEVIEIASSKDQNYNHIP--KDYSIPSGLDYLHLTTNNTIFGTQFKSIPE-TDAPL 164
Cdd:TIGR01364 79 EgkVADYIVTGAWSKKAAKEAKKYGVVNVVASGKEGNYTKIPdpSTWEISEDAAYVHYCANETIHGVEFRELPDvKNAPL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 165 VADMSSDIFSRTFDYSKFDLFYAGAQKNMGPAGTTLVIVKESLLGKVSRAIPSMMSYEVHASKDSMFNTPPVFAVYTSML 244
Cdd:TIGR01364 159 VADMSSNILSRPIDVSKFGLIYAGAQKNIGPAGLTVVIVRKDLLGRASRITPSMLNYKIHAENDSMYNTPPTFAIYVSGL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 245 NMRWIESQGGIRSLGDKNSVKSTLLYGEIDRNS-LFEGFAAKEDRSDMNATFNLKDTAYTEAFDSLCQTAGISGLKGHRS 323
Cdd:TIGR01364 239 VFKWLKEQGGVKAIEKRNQAKAQLLYDTIDNSNgFYRNPVDPRNRSRMNVVFTLGNEELEKRFLKEAEERGLVSLKGHRS 318
|
330 340 350
....*....|....*....|....*....|
gi 2474877695 324 VGGYRASMYNAMSIESVEILVDCMQILEKK 353
Cdd:TIGR01364 319 VGGMRASIYNAMPLEGVQALVDFMKEFQKK 348
|
|
| PLN02452 |
PLN02452 |
phosphoserine transaminase |
2-348 |
2.60e-113 |
|
phosphoserine transaminase
Pssm-ID: 178071 Cd Length: 365 Bit Score: 333.97 E-value: 2.60e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 2 RLHNFSAGPSILPKEVMHQAAEAVKELDGSKLSLIEISHRSKAFIDIMDEACERALRLTGLEGKgYKAIFLQGGASLQFL 81
Cdd:PLN02452 7 RVFNFSAGPATLPANVLAKAQAELYNWEGSGMSVMEMSHRGKEFLSIIQKAEADLRELLDIPDN-YEVLFLQGGASTQFA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 82 MAAYNLL--ENKAGYLNTGTWSDKAIKEAKLFGEVIEIASSKDQNYNHIP--KDYSIPSGLDYLHLTTNNTIFGTQFKSI 157
Cdd:PLN02452 86 AIPLNLCkpGDKADFVVTGSWSKKAAKEAKKYCKTNVIASGKDEKYTKIPsvSEWELTPDAKFVHICANETIHGVEFKDY 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 158 PET-DAPLVADMSSDIFSRTFDYSKFDLFYAGAQKNMGPAGTTLVIVKESLLGKVSRAIPSMMSYEVHASKDSMFNTPPV 236
Cdd:PLN02452 166 PDVgNVPLVADMSSNFLSKPVDVSKYGVIYAGAQKNVGPSGVTIVIIRKDLIGNARPITPGMLDYKIHAENDSLYNTPPC 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 237 FAVYTSMLNMRWIESQGGIRSLGDKNSVKSTLLYGEIDrNSlfEGF----AAKEDRSDMNATFNLKDTAYTEAFDSLCQT 312
Cdd:PLN02452 246 FGIYMCGLVFEDLLAQGGLKAMEKRNIRKADLLYDAID-ES--NGFyvcpVEKSVRSLMNVPFTLGGSELEAEFVKEAAK 322
|
330 340 350
....*....|....*....|....*....|....*.
gi 2474877695 313 AGISGLKGHRSVGGYRASMYNAMSIESVEILVDCMQ 348
Cdd:PLN02452 323 AGMVQLKGHRSVGGMRASIYNAMPLAGVEKLVAFMK 358
|
|
| PRK12462 |
PRK12462 |
phosphoserine aminotransferase; Provisional |
5-354 |
7.95e-106 |
|
phosphoserine aminotransferase; Provisional
Pssm-ID: 183540 Cd Length: 364 Bit Score: 314.83 E-value: 7.95e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 5 NFSAGPSILPKEVMHQAAEAVKELDGSKLSLIEISHRSKAFIDIMDEAcERALR-LTGLEgKGYKAIFLQGGASLQFLMA 83
Cdd:PRK12462 7 NFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQA-EADLRdLLGIP-DEYGVVFLQGGSSLQFSMI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 84 AYNLLENKAG---YLNTGTWSDKAIKEAKLFGEVIEIASSKDQNYNHIPKDYSIPSGLD--YLHLTTNNTIFGTQFKSIP 158
Cdd:PRK12462 85 PMNFSRPGAAapeYVTTGYWSRKAIGEASRVAAMRVVWDGAASGYRTLPSLAELDWDARapFRHYVSNETVEGLQFPDAA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 159 ETD-APLVADMSSDIFSRTFDYSKFDLFYAGAQKNMGPAGTTLVIVKESLLGKVSRAIPSMMSYEVHASKDSMFNTPPVF 237
Cdd:PRK12462 165 GLPdSPLIADMSSDFMSRPFDVEAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNTPPVF 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 238 AVYTSMLNMRWIESQ-GGIRSLGDKNSVKSTLLYGEIDR-NSLFEGFAAKEDRSDMNATFNLKDTAYTEAFDSLCQTAGI 315
Cdd:PRK12462 245 AIYVMALVLRWIRDEiGGVHAMRDINARKAAMLYATLDAlNEVIDCHAHRAARSTMNVAFRFRQPRLDTLFKEQSTEAGF 324
|
330 340 350
....*....|....*....|....*....|....*....
gi 2474877695 316 SGLKGHRSVGGYRASMYNAMSIESVEILVDCMQILEKKQ 354
Cdd:PRK12462 325 CGLSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDFAIRH 363
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
5-343 |
5.49e-30 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 117.73 E-value: 5.49e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 5 NFSAGPSILPKEVMHQAAEAVKELDGSKLSliEISHRSKAFIDIMDEACERALRLTGLEGKgYKAIFLQGGASlQFLMAA 84
Cdd:pfam00266 3 LDSAATTQKPQEVLDAIQEYYTDYNGNVHR--GVHTLGKEATQAYEEAREKVAEFINAPSN-DEIIFTSGTTE-AINLVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 85 YNLLEN-KAG----YLNTGTWSDK-AIKEAKLFG--EVIEIASSKDQNYNHIPKDYSIPSGLDYLHLTTNNTIFGTQF-- 154
Cdd:pfam00266 79 LSLGRSlKPGdeivITEMEHHANLvPWQELAKRTgaRVRVLPLDEDGLLDLDELEKLITPKTKLVAITHVSNVTGTIQpv 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 155 ----KSIPETDAPLVADMSSDIFSRTFDYSKF--DLFYAGAQKNMGPAGTTLVIVKESLLGKVS--------RAIPSmMS 220
Cdd:pfam00266 159 peigKLAHQYGALVLVDAAQAIGHRPIDVQKLgvDFLAFSGHKLYGPTGIGVLYGRRDLLEKMPpllggggmIETVS-LQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 221 YEVHASKDSMFN--TPPVFAVYTSMLNMRWIESqGGIRSLGDKNSVKSTLLYGEIDRNSLFEGFAAKEDRSDMNATFNLK 298
Cdd:pfam00266 238 ESTFADAPWKFEagTPNIAGIIGLGAALEYLSE-IGLEAIEKHEHELAQYLYERLLSLPGIRLYGPERRASIISFNFKGV 316
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 2474877695 299 DTAYTEafdSLCQTAGISGLKGHRSV----------GGYRASMYNAMSIESVEIL 343
Cdd:pfam00266 317 HPHDVA---TLLDESGIAVRSGHHCAqplmvrlglgGTVRASFYIYNTQEDVDRL 368
|
|
| AGAT_like |
cd06451 |
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate ... |
6-240 |
3.25e-08 |
|
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT), serine-glyoxylate aminotransferase (SGAT), and 3-hydroxykynurenine transaminase (HKT). AGAT is a homodimeric protein, which catalyses the transamination of glyoxylate to glycine, and SGAT converts serine and glyoxylate to hydroxypyruvate and glycine. HKT catalyzes the PLP-dependent transamination of 3-hydroxykynurenine, a potentially toxic metabolite of the kynurenine pathway.
Pssm-ID: 99744 [Multi-domain] Cd Length: 356 Bit Score: 54.60 E-value: 3.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 6 FSAGPSILPKEVMhQAaeavkeldgskLSLIEISHRSKAFIDIMDEACERALRLTGLEgkGYKAIFLQGGASLQFLMAAY 85
Cdd:cd06451 3 LIPGPSNVPPRVL-KA-----------MNRPMLGHRSPEFLALMDEILEGLRYVFQTE--NGLTFLLSGSGTGAMEAALS 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 86 NLLENKAGYLN--TGTWSDKAIKEAKLFG-EVIEIASSKDQNYNhiPKDY-SIPSGLDY--LHLTTNNTIFGTQF----- 154
Cdd:cd06451 69 NLLEPGDKVLVgvNGVFGDRWADMAERYGaDVDVVEKPWGEAVS--PEEIaEALEQHDIkaVTLTHNETSTGVLNplegi 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 155 -KSIPETDAPLVADMSSDIFSRTFDYSKF--DLFYAGAQKNMG-PAGTTLVIVKESLLGKVSRAIPSMMSY-------EV 223
Cdd:cd06451 147 gALAKKHDALLIVDAVSSLGGEPFRMDEWgvDVAYTGSQKALGaPPGLGPIAFSERALERIKKKTKPKGFYfdlllllKY 226
|
250
....*....|....*..
gi 2474877695 224 HASKDSMFNTPPVFAVY 240
Cdd:cd06451 227 WGEGYSYPHTPPVNLLY 243
|
|
| PRK03080 |
PRK03080 |
phosphoserine transaminase; |
5-307 |
1.63e-07 |
|
phosphoserine transaminase;
Pssm-ID: 235103 Cd Length: 378 Bit Score: 52.50 E-value: 1.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 5 NFSAGPSILPKEvmhqaaeavKELDGSKLSLIEISHRSKAFIDIMDEACERALRLTGLEgKGYKAIFLQGGASLQFLMAA 84
Cdd:PRK03080 15 RFSSGPCKKRPG---------WQLEALADALLGRSHRQKPVKALLKRVIEGTRELLSLP-EGYEVGIVPGSDTGAWEMAL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 85 YNLL-ENKAGYLNTGTWSDK----AIKEAKLfGEVIEIASskdqNYNHIPKdysiPSGLDYLH---LTTNNTIFGTQFKS 156
Cdd:PRK03080 85 WSLLgARRVDHLAWESFGSKwatdVVKQLKL-EDPRVLEA----DYGSLPD----LSAVDFDRdvvFTWNGTTTGVRVPV 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 157 ---IPETDAPLVA-DMSSDIFSRTFDYSKFDLFYAGAQKNMG-PAGTTLVIVK-------ESLlgKVSRAIP---SMMSY 221
Cdd:PRK03080 156 arwIGADREGLTIcDATSAAFALPLDWSKLDVYTFSWQKVLGgEGGHGMAILSpraverlESY--TPARPIPkffRLTKG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 222 E--VHAS-KDSMFNTPPVFAVYTSMLNMRWIESQGGIRSLGDKNSVKSTLLYGEIDRNSLFEGFAAK-EDRSDMNATFNL 297
Cdd:PRK03080 234 GkaIENSfKGQTINTPSMLTVEDYLDQLDWANSIGGLDALIARTAANASVLYDWAEKTPWATPLVADpATRSNTSVTLDF 313
|
330
....*....|
gi 2474877695 298 KDTayTEAFD 307
Cdd:PRK03080 314 VDA--QAAVD 321
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
49-204 |
1.81e-07 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 50.46 E-value: 1.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 49 MDEACERALRLTGlegKGYKAIFLQGGASLQFLMAAYNLLENKAG--YLNTGTWSDKAIKEAKLFGEVIEIASSKDQ--- 123
Cdd:cd01494 2 LEELEEKLARLLQ---PGNDKAVFVPSGTGANEAALLALLGPGDEviVDANGHGSRYWVAAELAGAKPVPVPVDDAGygg 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2474877695 124 NYNHIPKDYSIPSGLDYLHLTTNNTIFG-----TQFKSIP-ETDAPLVADMSSDIFSRTF-----DYSKFDLFYAGAQKN 192
Cdd:cd01494 79 LDVAILEELKAKPNVALIVITPNTTSGGvlvplKEIRKIAkEYGILLLVDAASAGGASPApgvliPEGGADVVTFSLHKN 158
|
170
....*....|..
gi 2474877695 193 MGPAGTTLVIVK 204
Cdd:cd01494 159 LGGEGGGVVIVK 170
|
|
|