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Conserved domains on  [gi|321398233|emb|CBX20845|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Castor canadensis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 1.60e-154

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 437.36  E-value: 1.60e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   1 MNPTAKLIILPTVIMGTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLD 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  81 SGQWSITHTQNYITSFMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSINHQLLMLMALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAIIPYSPMAFMLNLTIYILLTITMFTMINHNTNTSTLTLAHSWNVTPMI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 241 TPMLLISLLSLGGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLVYSTTLTLFPTTSTTKMKWRHPNN 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 321398233 321 KPSILLPPLFIITTMTLPLTPLMFTLS 347
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 1.60e-154

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 437.36  E-value: 1.60e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   1 MNPTAKLIILPTVIMGTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLD 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  81 SGQWSITHTQNYITSFMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSINHQLLMLMALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAIIPYSPMAFMLNLTIYILLTITMFTMINHNTNTSTLTLAHSWNVTPMI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 241 TPMLLISLLSLGGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLVYSTTLTLFPTTSTTKMKWRHPNN 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 321398233 321 KPSILLPPLFIITTMTLPLTPLMFTLS 347
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 11-221 3.61e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 102.50  E-value: 3.61e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  11 PTVIMGTTITMM----SSHWLVMWAGLEINMLAFIPLL-INKGSPRSTEAATKYFMTQATASMLLLMAIVI-----NTLD 80
Cdd:COG1007  105 YALLLFATLGMMlmasANDLLTLFLGLELLSLSLYVLVaFRRDDRRSSEAALKYFLLGALSSGFLLYGISLlygatGSLN 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  81 SGQWSITHTQNYITSFMALMALTM-------KLGLAPFHLWVPEVTQG-----TTLMS------GMLLLtwqklapISIL 142
Cdd:COG1007  185 LAGIAAALAAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGaptpvTAFLAtapkiaAFAAL-------LRLL 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 143 YQLMPSINH---QLLMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM-AIIPYSPMAF---MLNLTIYILLTITM 215
Cdd:COG1007  258 VEAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLlGLAAGTPLGVsaaLFYLLAYLFMNLGA 337


                 ....*.
gi 321398233 216 FTMINH 221
Cdd:COG1007  338 FAVILL 343
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-220 4.28e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 94.30  E-value: 4.28e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   23 SSHWLVMWAGLEINMLAFIPLL-INKGSPRSTEAATKYFMTQATASMLLLMAIVI-----NTLDSGQWSITHTQNY---- 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLmynytGTLSFDELSKALTGGLnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   93 --ITSFMALMALTMKLGLAPFHLWVPEVTQGT-TLMSGMLLLTWQKLAPISI-----LYQLMPSINHQLLMLMALLSIMV 164
Cdd:pfam00361  81 llLLFLLILVGFLFKSAQVPFHTWLPDAYEGApTPVSALLAATLVKAGGYGLirrslLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  165 GGWGGLNQTQLRKIMAYSSIAHMGWMMAII----PYSPMAFMLNLTIYILLTITMFTMIN 220
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAG 220
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-297 5.96e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 90.39  E-value: 5.96e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233    8 IILPTVIMGTTITMMSSHWLVMWAGLEINMLAFIPLL-INKGSPRSTEAATKYFMTQATASMLLLMAIVINTLDSGQWSI 86
Cdd:TIGR01770 106 ILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNF 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   87 THTQNYITSFMA------------LMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSI----- 149
Cdd:TIGR01770 186 EDLLLFLSNGMLnisllllgivliLVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfs 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  150 --NHQLLMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAHMGW-MMAIIPYSPM---AFMLNLTIYILLTITMFTM----- 218
Cdd:TIGR01770 266 eaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiLIGLLAGTLEgikAVLFYIFIYALMSLGAFGVlsllr 345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  219 -INHNTNTSTLTLAHSWNVTPMITPMLLISLLSLGGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLV 297
Cdd:TIGR01770 346 sYKDEWIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 1.60e-154

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 437.36  E-value: 1.60e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   1 MNPTAKLIILPTVIMGTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLD 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  81 SGQWSITHTQNYITSFMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSINHQLLMLMALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAIIPYSPMAFMLNLTIYILLTITMFTMINHNTNTSTLTLAHSWNVTPMI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 241 TPMLLISLLSLGGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLVYSTTLTLFPTTSTTKMKWRHPNN 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 321398233 321 KPSILLPPLFIITTMTLPLTPLMFTLS 347
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-346 6.34e-116

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 339.47  E-value: 6.34e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   1 MNPTAKLIILPTVIMGTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLD 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  81 SGQWSITHTQNYITSFMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSiNHQLLMLMALL 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAIIPYSPMAFMLNLTIYILLTITMFTMINHNTNTSTLTLAHSWNVTPMI 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 241 TPMLLISLLSLGGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLVYSTTLTLFPTTSTTKMKWRHPNN 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330       340
                 ....*....|....*....|....*.
gi 321398233 321 KPSILLPPLFIITTMTLPLTPLMFTL 346
Cdd:MTH00135 320 QLTLPLAISTTATLMLLPLTPAILAL 345
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.54e-111

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 327.55  E-value: 2.54e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   1 MNPTAKLIILPTVIMGTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLD 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  81 SGQWSITHTQNYITSFMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSINHQLLMLMALL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAIIPYSPMAFMLNLTIYILLTITMFTMINHNTNTSTLTLAHSWNVTPMI 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 241 TPMLLISLLSLGGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLVYSTTLTLFPTTSTTKMKWRHPNN 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*.
gi 321398233 321 KPSiLLPPLFIITTMTLPLTPLMFTL 346
Cdd:MTH00112 321 KNT-LTATLTTLSTLLLPLSPMILTI 345
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-346 8.29e-107

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 316.09  E-value: 8.29e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   1 MNPTAKLIILPTVIMGTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLD 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  81 SGQWSITHTQNYITSFMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSINHQLLMLMALL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAIIPYSPMAFMLNLTIYILLTITMFTMINHNTNTSTLTLAHSWNVTPMI 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 241 TPMLLISLLSLGGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLVYSTTLTLFPTTSTTKMKWRHpNN 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRF-KN 319

                        330       340
                 ....*....|....*....|....*.
gi 321398233 321 KPSILLPPLFIITTMTLPLTPLMFTL 346
Cdd:MTH00070 320 KTNNLLSLTIILSLMLLPITPTILNL 345
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-347 2.39e-84

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 259.13  E-value: 2.39e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   1 MNPTAKLIILPTVIMGTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLD 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  81 SGQWSITHTQNYITSFMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSINHQLLMLMALL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAIIPYSPMAFMLNLTIYILLTITMFTMINHNTNTSTLTLAHSWNVTPMI 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 241 TPMLLISLLSLGGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLVYSTTLTLFPTTSTTKMKWRHPNN 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....*..
gi 321398233 321 KpSILLPPLFIITTMTLPLTPLMFTLS 347
Cdd:MTH00200 321 S-NLLVGLLLLLSILGLPLTPQLLFLF 346
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-346 2.71e-80

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 248.69  E-value: 2.71e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   1 MNPTAKLIILPTVIMGTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLD 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  81 SGQWSITHTQNYITSFMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSINHQLLMLMALL 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAIIPYSPMAFMLNLTIYILLTITMFtMINHNTNTSTL-TLAHSWNVTPM 239
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIF-LIGNNFSLSTLsHLNKLSQLNPI 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 240 ITPMLLISLLSLGGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLVYSTTLTLFPTTSTTKMKWRHPN 319
Cdd:MTH00041 240 SAFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSG 319

                        330       340
                 ....*....|....*....|....*....
gi 321398233 320 NKPS--ILLPPLFIITTMTLPLTPLMFTL 346
Cdd:MTH00041 320 NITVygVILSILSSISILGLLLIPLFLSF 348
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-346 3.32e-52

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 175.78  E-value: 3.32e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   1 MNPTAKLIILPTVIMGTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLd 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  81 sgqwsITHTQNYITSFMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMpsiNHQLLMLMALL 160
Cdd:MTH00160  81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI---NNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAIIPYSPMAFMLNLTIYILLTITMFTMINHNTNTSTLTLAHSWNVTPMI 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 241 TPMLLISLLSLGGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLVYSTTLTLFPTTSTTKMKwrhPNN 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKK---KKN 309

                        330       340
                 ....*....|....*....|....*.
gi 321398233 321 KPSILLPPLFIITTMTLPLTPLMFTL 346
Cdd:MTH00160 310 KFSLILNFLSFISLFGLILSSLLFLL 335
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 13-315 1.69e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 168.53  E-value: 1.69e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  13 VIMGTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLDSGQWsithtqny 92
Cdd:MTH00144  13 MVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW-------- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  93 ITSFMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSINHQ-LLMLMALLSIMVGGWGGLN 171
Cdd:MTH00144  85 FSMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAyLLCVISVLSALVGSIGGLN 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 172 QTQLRKIMAYSSIAHMGWMMAIIPYSPMAFMLNLTIYILLTITMFTMINhNTNTSTLTLAHSWNVTPMITPMLLISLLSL 251
Cdd:MTH00144 165 QTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLW-SGDSGSMKDLGSLKPSYKTGLSIISLLLSL 243

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 321398233 252 GGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLVYSTTLTLFPTTSTTKMKW 315
Cdd:MTH00144 244 GGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 12-301 4.33e-45

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 156.86  E-value: 4.33e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  12 TVIMGTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVIntldsgQWSITHTQN 91
Cdd:MTH00011  14 TMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTM------MWSFPSLLK 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  92 YITSFMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSINHQLLMLMALLSIMVGGWGGLN 171
Cdd:MTH00011  88 NITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMN 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 172 QTQLRKIMAYSSIAHMGWMMAIIPYSPMAFMLNLTIYILLTITMFTMINHNTNTSTLTLAHSWNVTPMITPMLLISLLSL 251
Cdd:MTH00011 168 QTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSL 247

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 321398233 252 GGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLVYSTT 301
Cdd:MTH00011 248 GGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFM 297
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-339 7.12e-36

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 132.49  E-value: 7.12e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   8 IILPTVIMGTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLDSGQWSIT 87
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYLSLLS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  88 HtqnyitsFMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLmpSINHQLLMLMALLSIMVGGW 167
Cdd:MTH00197  82 V-------VLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFN--SSSFMGLLICSVLSSLIGGI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 168 GGLNQTQLRKIMAYSSIAHMGWMMAIIPYSPMAFMLNLTIYILLTItMFTMINHNTNTSTLTLAHSWNVTP-MITPMLLI 246
Cdd:MTH00197 153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMF-MLFLFLSKNNLSSLNQQYSNPESMsSNLVFLGL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 247 SLLSLGGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLVYSTTLTLFPTTSTTKMKwrhpnnkpSILL 326
Cdd:MTH00197 232 SFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKI--------NLLY 303

                        330
                 ....*....|...
gi 321398233 327 PPLFIITTMTLPL 339
Cdd:MTH00197 304 SGLFILLMMMLPL 316
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-297 1.14e-24

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 102.80  E-value: 1.14e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  13 VIMGTTITMMSSHWLVMWAGLEINMLA-FIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIV-------------INT 78
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSlFILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCAllcgttgglhlsyINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  79 LDSGQWSITHTQNYITSFMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSINhqLLMLMA 158
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 159 LLSIMVGGWGGLNQTQLRKIMAYSSIAHMG---WMMAIIPY-SPMAFMLNLTIYILLTITMFTMI-NHNTNTSTLT-LAH 232
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGfvlWGIEIGSFeSIQASLVYLFIYIIMSICVFSIIlALNVYKNLIIeFSG 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 321398233 233 SWNVTPMITPMLLISLLSLGGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLV 297
Cdd:MTH00196 240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 11-221 3.61e-24

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 102.50  E-value: 3.61e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  11 PTVIMGTTITMM----SSHWLVMWAGLEINMLAFIPLL-INKGSPRSTEAATKYFMTQATASMLLLMAIVI-----NTLD 80
Cdd:COG1007  105 YALLLFATLGMMlmasANDLLTLFLGLELLSLSLYVLVaFRRDDRRSSEAALKYFLLGALSSGFLLYGISLlygatGSLN 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  81 SGQWSITHTQNYITSFMALMALTM-------KLGLAPFHLWVPEVTQG-----TTLMS------GMLLLtwqklapISIL 142
Cdd:COG1007  185 LAGIAAALAAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGaptpvTAFLAtapkiaAFAAL-------LRLL 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 143 YQLMPSINH---QLLMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM-AIIPYSPMAF---MLNLTIYILLTITM 215
Cdd:COG1007  258 VEAFPGLAAdwqLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLlGLAAGTPLGVsaaLFYLLAYLFMNLGA 337


                 ....*.
gi 321398233 216 FTMINH 221
Cdd:COG1007  338 FAVILL 343
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 8-219 3.33e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 99.71  E-value: 3.33e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   8 IILPTVIMGTTITMMSSHWLVMWAGLEINMLA-FIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLDSGQWSI 86
Cdd:MTH00199 101 ILILIVALGSLLLVSSINWLSIYLAIELQTLTlFILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSI 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  87 tHTQNYITS-----FMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSINhqLLMLMALLS 161
Cdd:MTH00199 181 -QGINSILTgdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTN--VVLICAVLS 257

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 321398233 162 IMVGGWGGLNQTQLRKIMAYSSIAHMG---WMMAIIPYSPM-AFMLNLTIYILLTITMFTMI 219
Cdd:MTH00199 258 IIYGAIGALNQTKIKRLLAYSGIGHMGfilFGVAIGSFESIqASLIYMIIYVIMSICSFSII 319
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-220 4.28e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 94.30  E-value: 4.28e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   23 SSHWLVMWAGLEINMLAFIPLL-INKGSPRSTEAATKYFMTQATASMLLLMAIVI-----NTLDSGQWSITHTQNY---- 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLmynytGTLSFDELSKALTGGLnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   93 --ITSFMALMALTMKLGLAPFHLWVPEVTQGT-TLMSGMLLLTWQKLAPISI-----LYQLMPSINHQLLMLMALLSIMV 164
Cdd:pfam00361  81 llLLFLLILVGFLFKSAQVPFHTWLPDAYEGApTPVSALLAATLVKAGGYGLirrslLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  165 GGWGGLNQTQLRKIMAYSSIAHMGWMMAII----PYSPMAFMLNLTIYILLTITMFTMIN 220
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAG 220
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
14-221 2.83e-20

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 91.42  E-value: 2.83e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  14 IMGTTITMMSSHWLVMWAGLEINMLA-FIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLDSGQWSITHTQNY 92
Cdd:PRK05777 113 LLGMMVMVSANDLLTLFLGLELLSLPlYALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIAKA 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  93 ITSFMA------------LMALTMKLGLAPFHLWVPEVTQG-----TTLMSgmlllTWQKLAPISILYQL-------MPS 148
Cdd:PRK05777 193 LADGSGnsllllfglvflLVGLAFKLSAVPFHMWTPDVYEGaptpvTAFLA-----TAPKIAAFAVLLRLlvvafggLSE 267

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 321398233 149 INHQLLMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM-AIIPYSPMAF---MLNLTIYILLTITMFTMINH 221
Cdd:PRK05777 268 DWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLvGLAAGTAEGYsavLFYLLAYLFMTLGAFGVISL 344
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 8-297 5.96e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 90.39  E-value: 5.96e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233    8 IILPTVIMGTTITMMSSHWLVMWAGLEINMLAFIPLL-INKGSPRSTEAATKYFMTQATASMLLLMAIVINTLDSGQWSI 86
Cdd:TIGR01770 106 ILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNF 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   87 THTQNYITSFMA------------LMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSI----- 149
Cdd:TIGR01770 186 EDLLLFLSNGMLnisllllgivliLVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfs 265

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  150 --NHQLLMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAHMGW-MMAIIPYSPM---AFMLNLTIYILLTITMFTM----- 218
Cdd:TIGR01770 266 eaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiLIGLLAGTLEgikAVLFYIFIYALMSLGAFGVlsllr 345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  219 -INHNTNTSTLTLAHSWNVTPMITPMLLISLLSLGGLPPLTGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLV 297
Cdd:TIGR01770 346 sYKDEWIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 14-192 9.02e-14

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 71.72  E-value: 9.02e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  14 IMGTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLDSGQWSITHTQNYI 93
Cdd:COG0651  117 LAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARL 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  94 TSF----------MALMALTMKLGLAPFHLWVPEV-----TQGTTLMSGMLLltwqKLAPISIL--YQLMPSIN-----H 151
Cdd:COG0651  197 AELdpglllaafaLLLVGFGIKAALFPLHFWLPDAypaapSPVSALLSGLLT----KVGVYAILrvLTLLFGADpalflG 272

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 321398233 152 QLLMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMA 192
Cdd:COG0651  273 TLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILL 313
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 3-219 4.95e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 69.89  E-value: 4.95e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   3 PTAKLIILPTVIMGTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRST---------EAATKYFMTQATASMLLLMA 73
Cdd:MTH00198 187 PRSGFALVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFG 266

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  74 ----------------IVINTLDSGqwSITHTQNYITSFMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLA 137
Cdd:MTH00198 267 calyfgftgnegmlgtILSATLETT--NIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFT 344

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 138 PISILYQLMpsINHQLLMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAIIPYSPMAFMLN----LTIYILLTI 213
Cdd:MTH00198 345 VYILLTSLV--ITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQAswtyAVTYLVSAL 422


                 ....*.
gi 321398233 214 TMFTMI 219
Cdd:MTH00198 423 ASFTVI 428
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 48-221 7.44e-11

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 63.18  E-value: 7.44e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  48 GSPRSTEAATKYFMTQATASMLLLMAIVINTLDSGQWS----------ITHTQNYITSFMALMALTMKLGLAPFHLWVPE 117
Cdd:COG1008  155 GGERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALTfdiaelaaapLPLTAQLLLFLAFFIAFAVKVPMFPFHTWLPD 234

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 118 V-----TQGTTLMSGMLLltwqKLAP---ISILYQLMPSINHQ---LLMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAH 186
Cdd:COG1008  235 AhveapTAGSVLLAGVLL----KMGGyglLRFALPLFPEASAYfapLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSH 310

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 321398233 187 MGWMMAIIpyspmaFMLNLTIyilLTITMFTMINH 221
Cdd:COG1008  311 MGFVLLGI------FALNPLG---LQGAVLQMVSH 336
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 48-230 2.01e-09

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 58.41  E-value: 2.01e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   48 GSPRSTEAATKYFMTQATASMLLLMAIVINTLDSG---------QWSITHTQNYITSFMALMALTMKLGLAPFHLWVPEV 118
Cdd:TIGR01972 150 GGPNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGgtfdllellNLPLPFGVQTWLFLAFFIAFAVKVPLFPLHTWLPDA 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  119 -TQGTTLMSGMLLLTWQKLAP---ISILYQLMPSINHQ---LLMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:TIGR01972 230 hVEAPTAGSVILAGVLLKMGTygfLRFNLPLFPDASLYfapVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 321398233  192 AIIpyspmaFMLNLTIYILltiTMFTMINHNTNTSTLTL 230
Cdd:TIGR01972 310 LGI------FSFNELGISG---AVFQMISHGLITAALFL 339
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-341 5.80e-09

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 51.49  E-value: 5.80e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 321398233  291 YFYVRLVYSTTLTLFPTTSTTKMKWRHPNNKPSILLPPLFIITTMTLPLTP 341
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 48-221 8.48e-08

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 53.67  E-value: 8.48e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  48 GSPRSTEAATKYFMTQATASMLLLMAI----VINTLDSGQWSITHTQNYITS-------FMALM-ALTMKLGLAPFHLWV 115
Cdd:PRK05846 155 GGKNRIYAATKFFLYTLLGSLLMLVAIiylvVVYYNATGTFDIADLLNLPLPpgvqywlFLAFFiAFAVKMPMFPLHTWL 234

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 116 PEV-----TQGTTLMSGMLLltwqKLAP---ISILYQLMPSINHQ---LLMLMALLSIMVGGWGGLNQTQLRKIMAYSSI 184
Cdd:PRK05846 235 PDAhvqapTAGSVLLAGILL----KMGAyglLRFSLPLFPDASHEfapIIITLGVIAIIYGALVALAQTDIKKLIAYSSI 310

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 321398233 185 AHMGWMMAIIpyspmaFMLNltiYILLTITMFTMINH 221
Cdd:PRK05846 311 SHMGFVTLGI------FAGN---QLGIQGAIFQMISH 338
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-191 1.51e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 49.49  E-value: 1.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  33 LEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVI-----NTLD----SGQWSITHTQNYITSFMALmALT 103
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLlygvtGTLNmadlAGALAENPTVVTAFGFVLL-ALA 213

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 104 MKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSI----------NHQLLMLMALLSIMVGGWGGLNQT 173
Cdd:PRK08375 214 LKAAVFPLHTWLPRAYPAAPPVVTALLSGLVTKVAVYALIRIYFTVfggdfrfalgLGWLLAVLALLSMLVGSLAALGQD 293

                        170
                 ....*....|....*...
gi 321398233 174 QLRKIMAYSSIAHMGWMM 191
Cdd:PRK08375 294 DVKRVLAYSTVSQMGYIL 311
PRK08168 PRK08168
NADH-quinone oxidoreductase subunit L;
13-191 1.85e-05

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236171 [Multi-domain]  Cd Length: 516  Bit Score: 46.23  E-value: 1.85e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  13 VIMGTTITMMSSHWLVM---WAGLEI---NMLAFIPllinkGSPRSTEAATKYFMTQATASMLLLMAIVINTLDSGQWSI 86
Cdd:PRK08168 109 VLAAVHLLVLSDHLLVLiaaWAAISLalhRLLCFYP-----DRPFARLAAHKKFIADRLAELLLLAAAALAYLEVGSLSL 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  87 -----------THTQNYITSFMALMALTMKLGLAPFHLWVPEVTQGTTLMS-----------GMLLLtwqKLAPisILYQ 144
Cdd:PRK08168 184 salwahlaaqgASPSLQAAALLLVLAVILKTAQLPVHGWLIQVMEAPTPVSallhagvvnlgGFVLI---RFAP--LLEQ 258

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 321398233 145 LMPSInhQLLMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:PRK08168 259 APPAR--WLLVLVGLATAVLAGLVMLTRISIKVRLAWSTVAQMGFML 303
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 48-191 2.16e-05

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 46.18  E-value: 2.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  48 GSPRSTEAATKYFMTQATASMLLLMAIVINTLDSGQWSITHTQ----NYITSFMA------LMALTMKLGLAPFHLWVPE 117
Cdd:PRK12561 131 GGQKRLYAATKFILYTALASIFILVAGLALALSGDTFTFDLAElgakSYPLALELllyagfLIAFGVKLPIFPLHTWLPD 210

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 118 V-----TQGTTLMSGMLLltwqKL---APISILYQLMPSINHQLLMLMALLSIMVGGWGGLN---QTQLRKIMAYSSIAH 186
Cdd:PRK12561 211 AhgeasAPVSMILAGVLL----KMggyALIRFNVQMLPDAHVYFAPALAILGVVNIIYGALNafaQDNVKRRLAYSSVSH 286


                 ....*
gi 321398233 187 MGWMM 191
Cdd:PRK12561 287 MGFVL 291
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
47-263 2.54e-05

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 45.81  E-value: 2.54e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  47 KGSPRSTEAATKYFMTQATASMLLLMAI-VINTLDSGQWSITHTQNYIT---SFMALMALTM-------KLGLAPFHLWV 115
Cdd:PRK02504 154 KRDPRSNEAALKYLLIGAASSAIFLYGSsLLYGLSGGSTQLSAIALALItspSLGLALALVFviagiafKISAVPFHQWT 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 116 PEVTQGTTLMSGMLLLTWQKLA----PISILYQLMPSINHQ---LLMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAHMG 188
Cdd:PRK02504 234 PDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDEQwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAG 313

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 189 WMMAIIP------YSPMAFMLnlTIYILLTITMFTMI---NHNTNTSTLT-LAHSWNVTPMITPMLLISLLSLGGLPPLT 258
Cdd:PRK02504 314 FVMIGLVagteagYASMVFYL--LAYLFMNLGAFACVilfSLRTGTDQISdYAGLYQKDPLLTLGLSLCLLSLGGIPPLA 391


                 ....*
gi 321398233 259 GFLPK 263
Cdd:PRK02504 392 GFFGK 396
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 20-190 4.98e-05

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 44.92  E-value: 4.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  20 TMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFM------TQATASMLLLMA----IVINTLDSGQWS--IT 87
Cdd:PRK06458 124 ALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYAnaatVMGDGEMAILWTelLK 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  88 HTQNYITSFM------ALMALTMKLGLAPFHLWVPEV-TQGTTLMSGML---LLTWQKLAPISIlYQLMPSINH-----Q 152
Cdd:PRK06458 204 HASLLDPTLMklafvfLLIGFGTKVGLFPMHAWLPDAhSEAPSPVSALLsgvLLNVALYAVLRY-YILIDAAIGsdfpgR 282

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 321398233 153 LLMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWM 190
Cdd:PRK06458 283 LLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLI 320
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 100-188 2.79e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 42.73  E-value: 2.79e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 100 MALTMKLGLAPFHLWVPEV-----TQGTTLMSGMLLltwqKLAP---ISILYQLMPSINH---QLLMLMALLSIMVGGWG 168
Cdd:MTH00217 214 LSLAIKIPKIPFHIWLPQAhveapVAGSVILAGVLL----KLGGygfIRFSWPLLPEASEyfsPLIQTLSLLAIIYGSLT 289

                         90       100
                 ....*....|....*....|
gi 321398233 169 GLNQTQLRKIMAYSSIAHMG 188
Cdd:MTH00217 290 TCRQVDLKRIIAYSSVAHMG 309
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 99-188 5.74e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 41.45  E-value: 5.74e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  99 LMALTMKLGLAPFHLWVPEV-----TQGTTLMSGmLLLTWQKLAPISILYQLMPSINHQL---LMLMALLSIMVGGWGGL 170
Cdd:MTH00226 237 FLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAG-ILLKLGGYGLVRLSWPILPLGAQNLapaVIAMGIVGIVYGSFATC 315

                         90
                 ....*....|....*...
gi 321398233 171 NQTQLRKIMAYSSIAHMG 188
Cdd:MTH00226 316 RQIDVKRLVAYSSVAHMG 333
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 46-231 6.71e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 41.50  E-value: 6.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  46 NKGSPRSTEAATKYFMTQATASMLLLMAIVI-----NTLDSGQWSITHTQNYITSFM----------------ALMALTM 104
Cdd:PRK12667 156 YRDRGDAVEAAIKYALIGAVGTTLYFLALAFlyatfGTLNMADLSAKIRGLSFPLTGglagnpplalgvalalALWAFTI 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 105 KLGLAPFHLWVPEV-----TQGTTLMSG-------------MLLLTWQKLAPISILYQLMPsinhqLLMLMALLSIMVGG 166
Cdd:PRK12667 236 KAAIFPNHFWLPDAhpaapSPVSAMLSGlvvnvgayaiirfLYTIFGISPSLIDFRAALSP-----ILIILGAVSAIIGA 310

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 321398233 167 WGGLNQTQLRKIMAYSSIAHMGW-MMAIIPYSPMAfmlnltiyilLTITMFTMINHNTNTSTLTLA 231
Cdd:PRK12667 311 LMMVVQKDVKRLLAYSTISHMGYiFMGIGIGTQLG----------LAAALFHIINHAIAKSLLFLA 366
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
48-191 1.08e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 40.84  E-value: 1.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  48 GSPRSTEAATKYFMTQATASMLLLMAIVINTLDSGQWS------ITHTQNYITSFMALMALTMKLG----LAPFHLWVPE 117
Cdd:PRK06473 151 GGQRRGYAATKFLLYTAISGILILVSFLGLVWLSGASSfdyeplRSHTLPLSTQLLLLAPILVGFGikipLVPFHTWLPD 230

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 118 V-----TQGTTLMSGMLLltwqKLAPISIL---YQLMPSINHQL---LMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAH 186
Cdd:PRK06473 231 AhveasTPVSVLLAGVLL----KLGTYGLLrfgVGLFPEAWVYLapwLATWAVVSVLYGASCAIAQKDMKKMVAYSSIGH 306


                 ....*
gi 321398233 187 MGWMM 191
Cdd:PRK06473 307 MGYIL 311
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 7-191 1.09e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 40.87  E-value: 1.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233   7 LIILPTVIMGTTITMmsshwLVMWAGLEInmLAFIPLLINKGSPRSTEAATKYF-MTQATASMLLLMAIVINTLD-SGQW 84
Cdd:PRK08667 122 LSMLGVVASANTFSF-----LFFWEIMAL--SSFFLVMNDYQEEETQRAGIFYFvMTQLSTVFLMLGIIVLFIQTgSFEL 194

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  85 SITHTQNYITSF---MALMALTMKLGLAPFHLWVPEV-----TQGTTLMSGMLLltwqKLAPISILYQLM----PSINHQ 152
Cdd:PRK08667 195 SPLGASAGILSLvflLLFLGFGIKAGIIPFHKWLPYAhpaspSNVSALMSGVML----KVAVYGLVRFLMdvlsPELWWG 270

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 321398233 153 LLMLMA-LLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:PRK08667 271 VLILLAgSISALLGVIYALKEHDLKGLLAYSSIENIGIIL 310
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 100-188 1.28e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 40.43  E-value: 1.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 100 MALTMKLGLAPFHLWVPEV-----TQGTTLMSGMLLltwqKLAPISIL---YQLMPSINHQLLMLMALLSIMVGGWGGL- 170
Cdd:MTH00204 217 LSLAVKIPQIPFHIWLPQAhveapVAGSVILAGILL----KLGGYGFLrfsWPLFPAASEYFAPLIVMLSVIAVIYGSLt 292

                         90       100
                 ....*....|....*....|
gi 321398233 171 --NQTQLRKIMAYSSIAHMG 188
Cdd:MTH00204 293 tcRQVDFKRLIAYSSVAHMG 312
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
16-191 1.43e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 40.47  E-value: 1.43e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  16 GTTITMMSSHWLVMWAGLEINMLAFIPLLINKGSPRSTEAATKYFMTQATASMLLLMAIVINTLDSGQWSITH----TQN 91
Cdd:PRK07363 119 GIAGALLAQNLLLFFLFYELELIPFYLLIAIWGGEKRGYASIKFLIYTAVSGLLVLAAFLGIVWLSGSTSFDYdaisTQN 198

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  92 Y------ITSFMALMALTMKLGLAPFHLWVP----EVTQGTTLMSGMLLLTWQKLAPISILYQLMPSINHQL---LMLMA 158
Cdd:PRK07363 199 LslntqlILLTGLLLGFGIKIPLVPLHTWLPdaytEASPAVAILLGGVLAKLGTYGLLRFGLQLFPQTWSLVapgLAIIG 278

                        170       180       190
                 ....*....|....*....|....*....|...
gi 321398233 159 LLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:PRK07363 279 TISVIYGALSAIAQKDIKRMVAYSSIGHMGYIL 311
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-266 2.44e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 39.70  E-value: 2.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  33 LEINMLAFIPLL-INKGSPRSTEAATKYFMTQATASMLLLMAIVI-----NTLDSGQWSITHTQN-YITSFMALM----A 101
Cdd:PRK08376 150 LEIMSIASYALVaFRNDTWEAIEAGIKYMFVGSLASSMVLLGIALlygqyGTLNMAYLAVKMSENpTVVAKIALAlfiaG 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 102 LTMKLGLAPFHLWVPEV-TQGTTLMSGMLLLtwqklAPISILYQLM--------PSINHQ----LLMLMALLSIMVGGWG 168
Cdd:PRK08376 230 LAMKSGAVPVHMWLPDAyPAAPSSISAMLLV-----IKQAGLYALArvlfsiygPAINLAtvgwVIIILGCLTMFVGVAM 304

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 169 GLNQTQLRKIMAYSSIAHMGWMM-----AIIPYSPMAF--------------MLNLTIYILLTITMFTMINHNTNTSTLT 229
Cdd:PRK08376 305 AVVQKDVKRLLAYHSVSQIGYMLlglgvGLAALGDPAMasygeialaggiyhIVNHALYKALLFLTAGAVIYETGTRNLN 384

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 321398233 230 ----LAHSwnvTPMITPMLLISLLSLGGLPPLTGFLPKWII 266
Cdd:PRK08376 385 elggLART---MPKTTIAFLIGAAAIVGLPPFNGFASKWLI 422
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-263 2.55e-03

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 39.60  E-value: 2.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  51 RSTEAATKYFMTQATASMLLLMAI-VINTLDSGQ---WSI------THTQNYITSFMALMALTM----KLGLAPFHLWVP 116
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYGFsWLYGLSGGEielQEIvnglinTQMYNSPGISIALIFITVgigfKLSLAPFHQWTP 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 117 EVTQGTTLMSGMLLLTWQKLA----PISILYQLMPSIN---HQLLMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAHMGW 189
Cdd:CHL00049 239 DVYEGSPTPVVAFLSVTSKVAasalATRIFDIPFYFSSnewHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGY 318

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 190 MM-AII---PYSPMAFMLNLT-IYILLTITMFTMI---NHNTNTSTLT-LAHSWNVTPMITPMLLISLLSLGGLPPLTGF 260
Cdd:CHL00049 319 VIiGIIvgdSNDGYASMITYMlFYIFMNLGTFACIvlfGLRTGTDNIRdYAGLYTKDPFLALSLALCLLSLGGIPPLAGF 398


                 ...
gi 321398233 261 LPK 263
Cdd:CHL00049 399 FGK 401
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 99-194 3.40e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 38.97  E-value: 3.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  99 LMALTMKLGLAPFHLWVPEV-TQGTTLMSGMLLLTWQKLAPISILYqlMPSINHQ---------LLMLMALLSIMVGGWG 168
Cdd:PRK08676 213 FIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGILR--LSALLRQsgaaeqfsnVLIGLGIFSIAVAAFS 290

                         90       100
                 ....*....|....*....|....*.
gi 321398233 169 GLNQTQLRKIMAYSSIAHMGWMMAII 194
Cdd:PRK08676 291 MLSQRNLKKLIAFSSIEHMGLMLLGI 316
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 96-315 3.77e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 38.70  E-value: 3.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  96 FMALMALTMKLGLAPFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMPSINHQLLMLMALLSIMVggwgGLNQTQL 175
Cdd:MTH00091  61 YFQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQ----MFLLKSY 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 176 RKIMAYSSIAHMGWMMAIIPYSpmaFMLNLTIYILLTITMFTMINHNTNTSTLTLAhSWNVTPMITPMLLISllslgglp 255
Cdd:MTH00091 137 KNLLILSSTESFNWLILSFFFS---FFNVFFLFFYYFLLMLFLIPKFNNVNKLNFV-SWETLLVFMNLPFSV-------- 204

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 256 pltGFLPKWIIIDELTKNDLILMPTTMAMMALLNLYFYVRLVYSTTLTLFPTTSTTKMKW 315
Cdd:MTH00091 205 ---TFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFF 261
PRK12650 PRK12650
DUF4040 family protein;
110-194 5.49e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 38.87  E-value: 5.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 110 PFHLWVPEVTQGTTLMSGMLLLTWQKLAPISILYQLMP-----SINHQLLMLMALLSIMVGGWGGLNQTQLRKIMAYSSI 184
Cdd:PRK12650 226 PFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPvfhdvAVWNWLLIIVGMITALMGAVFAVQKTDLKKLTAYSTV 305

                         90
                 ....*....|
gi 321398233 185 AHMGWMMAII 194
Cdd:PRK12650 306 SQLGWIVATI 315
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 48-191 6.97e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 38.15  E-value: 6.97e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233  48 GSPRSTEAATKYFMTQATASMLLLMAIVINTLDSGQWSITHT----QNYITSFMALM------ALTMKLGLAPFHLWVPE 117
Cdd:PRK02546 159 GGKKRQYAATKFILYTAGSSLFILLAALAMAFYGDTPTFDMTalaaKDFGLGFQLLCyaglliAYGVKLPIVPLHTWLPD 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 321398233 118 VTQGTTLMSGMLL----LTWQKLAPISILYQLMPSINHQ---LLMLMALLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWM 190
Cdd:PRK02546 239 AHGEATAPVHMLLagilLKMGGYALLRMNAGMLPDAHAQfapLLIVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFV 318


                 .
gi 321398233 191 M 191
Cdd:PRK02546 319 L 319
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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