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Conserved domains on  [gi|523424052|emb|CDF90382|]
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ZYBA0S06-07272g1_1 [Zygosaccharomyces bailii CLIB 213]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IPT smart00429
ig-like, plexins, transcription factors;
544-633 2.84e-15

ig-like, plexins, transcription factors;


:

Pssm-ID: 214657 [Multi-domain]  Cd Length: 90  Bit Score: 72.07  E-value: 2.84e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052    544 PPSIQRVIPAQGPINGGIEITLLGRNFKDGLVVNFGENV---ALSTQCWSETTMVTCLPPASC-AGQVFVSVANPTKGNT 619
Cdd:smart00429    1 DPVITRISPTSGPVSGGTEITLCGKNLKSISVVFVEVGVgeaPCTFSPSSSTAIVCKTPPYHNiPGSVPVRTVGLRNGGV 80

                            90
                    ....*....|....
gi 523424052    620 MethiSNQSVFTYV 633
Cdd:smart00429   81 P----SSPQPFTYV 90
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
723-792 2.36e-13

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 71.91  E-value: 2.36e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  723 DNLGRTLLQLASLKGYHTLCSVLIKKGARVNDRDFFGFSPLHFACVGGDTRVIRLLLQCKADATVKAYNG 792
Cdd:COG0666   117 DKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDG 186
 
Name Accession Description Interval E-value
IPT smart00429
ig-like, plexins, transcription factors;
544-633 2.84e-15

ig-like, plexins, transcription factors;


Pssm-ID: 214657 [Multi-domain]  Cd Length: 90  Bit Score: 72.07  E-value: 2.84e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052    544 PPSIQRVIPAQGPINGGIEITLLGRNFKDGLVVNFGENV---ALSTQCWSETTMVTCLPPASC-AGQVFVSVANPTKGNT 619
Cdd:smart00429    1 DPVITRISPTSGPVSGGTEITLCGKNLKSISVVFVEVGVgeaPCTFSPSSSTAIVCKTPPYHNiPGSVPVRTVGLRNGGV 80

                            90
                    ....*....|....
gi 523424052    620 MethiSNQSVFTYV 633
Cdd:smart00429   81 P----SSPQPFTYV 90
IPT cd00102
Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as ...
 545-634 9.97e-14

Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor receptors), as well as, cyclodextrin glycosyltransferase and similar enzymes. Although they are involved in DNA binding in transcription factors, their function in other proteins is unknown. In these transcription factors, IPTs form homo- or heterodimers with the exception of the nuclear factor of activated Tcells (NFAT) transcription factors which are mainly monomers.


Pssm-ID: 238050 [Multi-domain]  Cd Length: 89  Bit Score: 67.49  E-value: 9.97e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  545 PSIQRVIPAQGPINGGIEITLLGRNFKDG--LVVNFGENVALSTQCWSETTMVtCLPPASC---AGQVFVSVANPTKGNT 619
Cdd:cd00102     1 PVITSISPSSGPVSGGTEVTITGSNFGSGsnLRVTFGGGVPCSVLSVSSTAIV-CTTPPYAnpgPGPVEVTVDRGNGGIT 79

                          90
                  ....*....|....*
gi 523424052  620 methiSNQSVFTYVD 634
Cdd:cd00102    80 -----SSPLTFTYVP 89
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
723-792 2.36e-13

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 71.91  E-value: 2.36e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  723 DNLGRTLLQLASLKGYHTLCSVLIKKGARVNDRDFFGFSPLHFACVGGDTRVIRLLLQCKADATVKAYNG 792
Cdd:COG0666   117 DKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDG 186
TIG pfam01833
IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These ...
 545-632 2.49e-09

IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These domains are found in cell surface receptors such as Met and Ron as well as in intracellular transcription factors where it is involved in DNA binding. CAUTION: This family does not currently recognize a significant number of members.


Pssm-ID: 460355 [Multi-domain]  Cd Length: 84  Bit Score: 55.15  E-value: 2.49e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052   545 PSIQRVIPAQGPINGGIEITLLGRNF---KDGLVVNFGENVALSTqcWSETTMVTCLPPASCAGQVFVSVANPTKGNTme 621
Cdd:pfam01833    1 PVITSISPSSGPASGGTTITITGSNFgtdSSDLKVTIGGTPCTVI--SVSSTTIVCTTPPGTSGLVNVSVTVGGGGIS-- 76

                           90
                   ....*....|.
gi 523424052   622 thiSNQSVFTY 632
Cdd:pfam01833   77 ---SSPLTFTY 84
Ank_2 pfam12796
Ankyrin repeats (3 copies);
706-788 4.05e-09

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 54.74  E-value: 4.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052   706 LVKVIrsLHVNSNLSMCDNLGRTLLQLASLKGYHTLCSVLIKKgARVNDRDFfGFSPLHFACVGGDTRVIRLLLQCKADA 785
Cdd:pfam12796   12 LVKLL--LENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLEIVKLLLEKGADI 87


                   ...
gi 523424052   786 TVK 788
Cdd:pfam12796   88 NVK 90
PHA03095 PHA03095
ankyrin-like protein; Provisional
 708-803 3.46e-06

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 50.79  E-value: 3.46e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  708 KVIRSLHVnsnlSMCDNLGRTLLQLASLKGYHTLCSV-------LIKKGARVNDRDFFGFSPLHFACVGGDTRVIRLLLQ 780
Cdd:PHA03095  203 RIVRELIR----AGCDPAATDMLGNTPLHSMATGSSCkrslvlpLLIAGISINARNRYGQTPLHYAAVFNNPRACRRLIA 278

                          90       100
                  ....*....|....*....|...
gi 523424052  781 CKADATVKAYNGVSCKQLFVVNH 803
Cdd:PHA03095  279 LGADINAVSSDGNTPLSLMVRNN 301
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 759-784 7.33e-03

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 34.87  E-value: 7.33e-03
                            10        20
                    ....*....|....*....|....*.
gi 523424052    759 GFSPLHFACVGGDTRVIRLLLQCKAD 784
Cdd:smart00248    2 GRTPLHLAAENGNLEVVKLLLDKGAD 27
 
Name Accession Description Interval E-value
IPT smart00429
ig-like, plexins, transcription factors;
544-633 2.84e-15

ig-like, plexins, transcription factors;


Pssm-ID: 214657 [Multi-domain]  Cd Length: 90  Bit Score: 72.07  E-value: 2.84e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052    544 PPSIQRVIPAQGPINGGIEITLLGRNFKDGLVVNFGENV---ALSTQCWSETTMVTCLPPASC-AGQVFVSVANPTKGNT 619
Cdd:smart00429    1 DPVITRISPTSGPVSGGTEITLCGKNLKSISVVFVEVGVgeaPCTFSPSSSTAIVCKTPPYHNiPGSVPVRTVGLRNGGV 80

                            90
                    ....*....|....
gi 523424052    620 MethiSNQSVFTYV 633
Cdd:smart00429   81 P----SSPQPFTYV 90
IPT cd00102
Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as ...
 545-634 9.97e-14

Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor receptors), as well as, cyclodextrin glycosyltransferase and similar enzymes. Although they are involved in DNA binding in transcription factors, their function in other proteins is unknown. In these transcription factors, IPTs form homo- or heterodimers with the exception of the nuclear factor of activated Tcells (NFAT) transcription factors which are mainly monomers.


Pssm-ID: 238050 [Multi-domain]  Cd Length: 89  Bit Score: 67.49  E-value: 9.97e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  545 PSIQRVIPAQGPINGGIEITLLGRNFKDG--LVVNFGENVALSTQCWSETTMVtCLPPASC---AGQVFVSVANPTKGNT 619
Cdd:cd00102     1 PVITSISPSSGPVSGGTEVTITGSNFGSGsnLRVTFGGGVPCSVLSVSSTAIV-CTTPPYAnpgPGPVEVTVDRGNGGIT 79

                          90
                  ....*....|....*
gi 523424052  620 methiSNQSVFTYVD 634
Cdd:cd00102    80 -----SSPLTFTYVP 89
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
723-792 2.36e-13

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 71.91  E-value: 2.36e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  723 DNLGRTLLQLASLKGYHTLCSVLIKKGARVNDRDFFGFSPLHFACVGGDTRVIRLLLQCKADATVKAYNG 792
Cdd:COG0666   117 DKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDG 186
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
718-792 2.43e-13

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 71.91  E-value: 2.43e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 523424052  718 NLSMCDNLGRTLLQLASLKGYHTLCSVLIKKGARVNDRDFFGFSPLHFACVGGDTRVIRLLLQCKADATVKAYNG 792
Cdd:COG0666   145 DVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDG 219
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
640-794 8.50e-12

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 67.29  E-value: 8.50e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  640 LIELALQIVGLKMNGKLEDARNIAKRIVGNDGASSSMSSPSIPSSDGPRSNQDALDTQPLYSDENLLVKVIRSLHVNSNL 719
Cdd:COG0666     1 LLLLLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADI 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 523424052  720 SMCDNLGRTLLQLASLKGYHTLCSVLIKKGARVNDRDFFGFSPLHFACVGGDTRVIRLLLQCKADATVKAYNGVS 794
Cdd:COG0666    81 NAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNT 155
TIG pfam01833
IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These ...
 545-632 2.49e-09

IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These domains are found in cell surface receptors such as Met and Ron as well as in intracellular transcription factors where it is involved in DNA binding. CAUTION: This family does not currently recognize a significant number of members.


Pssm-ID: 460355 [Multi-domain]  Cd Length: 84  Bit Score: 55.15  E-value: 2.49e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052   545 PSIQRVIPAQGPINGGIEITLLGRNF---KDGLVVNFGENVALSTqcWSETTMVTCLPPASCAGQVFVSVANPTKGNTme 621
Cdd:pfam01833    1 PVITSISPSSGPASGGTTITITGSNFgtdSSDLKVTIGGTPCTVI--SVSSTTIVCTTPPGTSGLVNVSVTVGGGGIS-- 76

                           90
                   ....*....|.
gi 523424052   622 thiSNQSVFTY 632
Cdd:pfam01833   77 ---SSPLTFTY 84
Ank_2 pfam12796
Ankyrin repeats (3 copies);
706-788 4.05e-09

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 54.74  E-value: 4.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052   706 LVKVIrsLHVNSNLSMCDNLGRTLLQLASLKGYHTLCSVLIKKgARVNDRDFfGFSPLHFACVGGDTRVIRLLLQCKADA 785
Cdd:pfam12796   12 LVKLL--LENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLEIVKLLLEKGADI 87


                   ...
gi 523424052   786 TVK 788
Cdd:pfam12796   88 NVK 90
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
723-792 1.02e-08

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 58.04  E-value: 1.02e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  723 DNLGRTLLQLASLKGYHTLCSVLIKKGARVNDRDFFGFSPLHFACVGGDTRVIRLLLQCKADATVKAYNG 792
Cdd:COG0666   183 DNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDG 252
Ank_4 pfam13637
Ankyrin repeats (many copies);
726-779 1.20e-07

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 49.20  E-value: 1.20e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 523424052   726 GRTLLQLASLKGYHTLCSVLIKKGARVNDRDFFGFSPLHFACVGGDTRVIRLLL 779
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
Ank_2 pfam12796
Ankyrin repeats (3 copies);
730-780 2.41e-07

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 49.73  E-value: 2.41e-07
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 523424052   730 LQLASLKGYHTLCSVLIKKGARVNDRDFFGFSPLHFACVGGDTRVIRLLLQ 780
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLE 51
IPT_PCSR cd00603
IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup ...
 545-634 3.00e-06

IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the macrophage-stimulating receptors and of fibrocystin. Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT_PCSR domain present preceeded by SEMA (semaphorin) and PSI (plexin, semaphorin, integrin) domains.


Pssm-ID: 238337 [Multi-domain]  Cd Length: 90  Bit Score: 46.29  E-value: 3.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  545 PSIQRVIPAQGPINGGIEITLLGRNF---KDGLVVNFGEnvalsTQC----WSETTMVtCLPPAS---CAGQVFVSVanp 614
Cdd:cd00603     1 PVITSISPSSGPLSGGTRLTITGSNLgsgSPRVRVTVGG-----VPCkvlnVSSTEIV-CRTPAAatpGEGPVEVTV--- 71

                          90       100
                  ....*....|....*....|
gi 523424052  615 tKGNTMETHISNQSVFTYVD 634
Cdd:cd00603    72 -DGANVSARVLSNTTFTYVE 90
PHA03095 PHA03095
ankyrin-like protein; Provisional
 708-803 3.46e-06

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 50.79  E-value: 3.46e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  708 KVIRSLHVnsnlSMCDNLGRTLLQLASLKGYHTLCSV-------LIKKGARVNDRDFFGFSPLHFACVGGDTRVIRLLLQ 780
Cdd:PHA03095  203 RIVRELIR----AGCDPAATDMLGNTPLHSMATGSSCkrslvlpLLIAGISINARNRYGQTPLHYAAVFNNPRACRRLIA 278

                          90       100
                  ....*....|....*....|...
gi 523424052  781 CKADATVKAYNGVSCKQLFVVNH 803
Cdd:PHA03095  279 LGADINAVSSDGNTPLSLMVRNN 301
PHA03095 PHA03095
ankyrin-like protein; Provisional
 744-804 6.90e-06

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 50.02  E-value: 6.90e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 523424052  744 VLIKKGARVNDRDFFGFSPLHfACVGG---DTRVIRLLLQCKADATVKAYNGVSCKQLFVVNHG 804
Cdd:PHA03095  102 LLIKAGADVNAKDKVGRTPLH-VYLSGfniNPKVIRLLLRKGADVNALDLYGMTPLAVLLKSRN 164
IPT_COE cd01175
IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing ...
 545-616 2.07e-05

IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved in the regulation of the early stages of B-cell differentiation, Drosophila collier is a regulator of the head patterning, and a related protein in Xenopus is involved in primary neurogenesis. All COE family members have a well conserved DNA binding domain that contains an atypical Zn finger motif. The function of the IPT domain is unknown.


Pssm-ID: 238580  Cd Length: 85  Bit Score: 43.79  E-value: 2.07e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 523424052  545 PSIQRVIPAQGPINGGIEITLLGRNFKDGLVVNFGENVALSTQCWSETTMVTClPPASCAGQVFVSVANPTK 616
Cdd:cd01175     1 PCIKAISPSEGWTTGGATVIIIGDNFFDGLQVVFGTMLVWSELITPHAIRVQT-PPRHIPGVVEVTLSYKSK 71
IPT_TF cd00602
IPT domain of eukaryotic transcription factors NF-kappaB/Rel, nuclear factor of activated ...
 545-633 1.76e-04

IPT domain of eukaryotic transcription factors NF-kappaB/Rel, nuclear factor of activated Tcells (NFAT), and recombination signal J-kappa binding protein (RBP-Jkappa). The IPT domains in these proteins are involved in DNA binding. Most NF-kappaB/Rel proteins form homo- and heterodimers, while NFAT proteins are largely monomeric (with TonEBP being an exception). While the majority of sequence-specific DNA binding elements are found in the N-terminal domain, several are found in the IPT domain in loops adjacent to, and including, the linker region.


Pssm-ID: 238336  Cd Length: 101  Bit Score: 41.88  E-value: 1.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  545 PSIQRVIPAQGPINGGIEITLLGRNF-KDGLVVNFGENVALSTQcWSETTMVTCL-----------PP-----ASCAGQV 607
Cdd:cd00602     1 LPICRVSSLSGSVNGGDEVFLLCDKVnKPDIKVWFGEKGPGETV-WEAEAMFRQEdvrqvaivfktPPyhnkwITRPVQV 79

                          90       100
                  ....*....|....*....|....*.
gi 523424052  608 FVSVANPTKGNTMETHisnqsVFTYV 633
Cdd:cd00602    80 PIQLVRPDDRKRSEPL-----TFTYT 100
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 744-787 1.89e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 45.66  E-value: 1.89e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 523424052  744 VLIKKGARVNDRDFFGFSPLHFACVGGDTRVIRLLLQCKADATV 787
Cdd:PTZ00322  100 ILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTL 143
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 741-794 2.22e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 45.44  E-value: 2.22e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 523424052  741 LCSVLIKKGARVNDRDFFGFSPLHFACVGGDTRVIRLLLQCKADATVKAYNGVS 794
Cdd:PHA02876  160 IAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLS 213
IPT_plexin_repeat1 cd01180
First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are ...
 545-634 2.48e-04

First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present preceeded by SEMA (semaphorin) and PSI (plexin, semaphorin, integrin) domains.


Pssm-ID: 238585  Cd Length: 94  Bit Score: 41.15  E-value: 2.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  545 PSIQRVIPAQGPINGGIEITLLGRNFkdGLVVNF--------GENVALSTQCWSETTMVTCLPPAS----CAGQVFVSVA 612
Cdd:cd01180     1 PVITEFFPLSGPLEGGTRLTICGSNL--GLRKNDvrhgvrvgGVPCNPEPPEYSSSEKIVCTTGPAgnpvFNGPVEVTVG 78

                          90       100
                  ....*....|....*....|..
gi 523424052  613 NPTKGNTMETHisnqsvFTYVD 634
Cdd:cd01180    79 HGSFRTESSEG------FSFVD 94
PHA03095 PHA03095
ankyrin-like protein; Provisional
 688-792 2.61e-04

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 44.63  E-value: 2.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  688 RSNQDALDTQPLYSDENLLVKVIRSLHVNSNLSMCDNLGRTLLQLAsLKGYHTLC----SVLIKKGARVNDRDFFGFSPL 763
Cdd:PHA03095    9 IIMEAALYDYLLNASNVTVEEVRRLLAAGADVNFRGEYGKTPLHLY-LHYSSEKVkdivRLLLEAGADVNAPERCGFTPL 87

                          90       100       110
                  ....*....|....*....|....*....|
gi 523424052  764 H-FACVGGDTRVIRLLLQCKADATVKAYNG 792
Cdd:PHA03095   88 HlYLYNATTLDVIKLLIKAGADVNAKDKVG 117
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 695-795 3.24e-04

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 44.27  E-value: 3.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  695 DTQPLYSD-ENLLVKVIRSLHVNSNLSmcdnlgRTLLQlaslKGYH--TLCSV--LIKKGARVNDRDFFGFSPLHFACVG 769
Cdd:PHA03100  133 NVNIKNSDgENLLHLYLESNKIDLKIL------KLLID----KGVDinAKNRVnyLLSYGVPINIKDVYGFTPLHYAVYN 202

                          90       100
                  ....*....|....*....|....*.
gi 523424052  770 GDTRVIRLLLQCKADATVKAYNGVSC 795
Cdd:PHA03100  203 NNPEFVKYLLDLGANPNLVNKYGDTP 228
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 700-794 8.45e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 43.03  E-value: 8.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  700 YSDENLLVKVIRSL-HVNSNLSMCDNLGRTLLQLASLKGYHTLCSVLIKKGARVNDRDFFGFSPLHFACVGGDTRVIRLL 778
Cdd:PHA02874  130 YAIKKGDLESIKMLfEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIKLL 209

                          90
                  ....*....|....*.
gi 523424052  779 LQCKADATVKAYNGVS 794
Cdd:PHA02874  210 IDHGNHIMNKCKNGFT 225
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 700-784 1.64e-03

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 42.36  E-value: 1.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  700 YSDENLLVKVIRSLHVNSNLSMCDNlgrTLLQLASLKGYHTLCSVLIKKGARVNDRDFFGFSPLHFACVGGDTRVIRLLL 779
Cdd:PHA02876  319 YDTENIRTLIMLGADVNAADRLYIT---PLHQASTLDRNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLL 395


                  ....*
gi 523424052  780 QCKAD 784
Cdd:PHA02876  396 DYGAD 400
IPT_plexin_repeat2 cd01179
Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are ...
 545-633 4.91e-03

Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present preceeded by SEMA (semaphorin) and PSI (plexin, semaphorin, integrin) domains.


Pssm-ID: 238584  Cd Length: 85  Bit Score: 37.20  E-value: 4.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 523424052  545 PSIQRVIPAQGPINGGIEITLLGRNfkdglvVNFGENVALS---TQC---WSETTMVTCLPPASCAGQ---VFVSVANpt 615
Cdd:cd01179     1 PSITSLSPSYGPQSGGTRLTITGKH------LNAGSSVRVTvggQPCkilSVSSSQIVCLTPPSASPGeapVKVLIDG-- 72

                          90
                  ....*....|....*...
gi 523424052  616 kgntmeTHISNQSVFTYV 633
Cdd:cd01179    73 ------ARRLAPLVFTYT 84
Ank_5 pfam13857
Ankyrin repeats (many copies);
745-788 5.38e-03

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 36.17  E-value: 5.38e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 523424052   745 LIKKG-ARVNDRDFFGFSPLHFACVGGDTRVIRLLLQCKADATVK 788
Cdd:pfam13857    1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLK 45
Ank_3 pfam13606
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 758-784 7.12e-03

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.


Pssm-ID: 463933 [Multi-domain]  Cd Length: 30  Bit Score: 34.93  E-value: 7.12e-03
                           10        20
                   ....*....|....*....|....*..
gi 523424052   758 FGFSPLHFACVGGDTRVIRLLLQCKAD 784
Cdd:pfam13606    1 DGNTPLHLAARNGRLEIVKLLLENGAD 27
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 759-784 7.33e-03

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 34.87  E-value: 7.33e-03
                            10        20
                    ....*....|....*....|....*.
gi 523424052    759 GFSPLHFACVGGDTRVIRLLLQCKAD 784
Cdd:smart00248    2 GRTPLHLAAENGNLEVVKLLLDKGAD 27
Ank pfam00023
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 759-784 8.98e-03

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.


Pssm-ID: 459634 [Multi-domain]  Cd Length: 34  Bit Score: 34.96  E-value: 8.98e-03
                           10        20
                   ....*....|....*....|....*..
gi 523424052   759 GFSPLHFACV-GGDTRVIRLLLQCKAD 784
Cdd:pfam00023    2 GNTPLHLAAGrRGNLEIVKLLLSKGAD 28
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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