|
Name |
Accession |
Description |
Interval |
E-value |
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
1-839 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 1203.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 1 MILGVSTIFGFYYYVKPELPDVATLRDVELQTPMQVFSQDGKLISQFGEKRRNPVTYDEIPRHLVEALIATEDSRFYEHP 80
Cdd:COG5009 15 LLLGALAVAGLYLYLSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLLINAFLAAEDKRFYEHP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 81 GIDPIGITRAALVVAMSGSAKQGASTITQQLARNFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLGHRSY 160
Cdd:COG5009 95 GVDPIGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEILELYLNKIYLGHRAY 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 161 GFGAAARVYFGKDLPDLTLSEIATLAGMPKAPSTMNPIYSVERATNRRNVVLRRMLDEKYITQAEFDDARSEEIISKYHG 240
Cdd:COG5009 175 GVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEYEAAKAEPLTARYHG 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 241 AEIELSAPYVAEVARAWMVERYGEE-AYTSGMKVYTTVDSKLQKAANQAAIKNLLGYDERHGYRGAEKVLWQTAqsawdq 319
Cdd:COG5009 255 ASAEVDAPYFAEMVRRELVERYGEDaLYTGGLKVYTTLDPRLQEAAEKALRDGLLAYDRRHGYRGPEAHLDLAE------ 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 320 EQIVKHLKSQPTYGDLVPAVVTAVDSKSAQIWVKNQGEGTIEWQGMNWARKFLTDNRQGPAPSQAKEILAVGEQIWVRHE 399
Cdd:COG5009 329 EDWDEALAEVPDVGDLRPAVVLEVDDKSARVGLRDGETGTLPLEGLKWARPYINDNRRGPAPKSASDVLKPGDVIRVRPV 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 400 AVTGdevseepteesataesetpivWRLSQVPNANTAFVAMNPNNGAVLSMVGGFNFVHNKFNRATQSIRQVGSGIKPFI 479
Cdd:COG5009 409 ADGG---------------------WRLRQIPEVQGALVALDPHTGAVLALVGGFDFEQSKFNRATQAKRQPGSSFKPFV 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 480 YSAAIEKGLTLASLINDAPINQWDKSQGTAWRPKNSPPTYVGPTRLRIGLAQSKNVMAVRVLREVGLDDTRNYLTRFGFD 559
Cdd:COG5009 468 YAAALDNGYTPATIINDAPIVFDDGGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFGIY 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 560 iDEVPRSETIALGAGSLTPMKVAQGYSVFANGGYYVEPFYISRIETPFGETEFEATPKVVCkEDCQQQMTSDPMADEfae 639
Cdd:COG5009 548 -SKLPPNLSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADPARAC-EDCDAAEWDGAEPRL--- 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 640 qdvdakVQYAPQVISEQNAFLVREMMYSNIwgggdwsagtgWNGTGWRAQPLKrRDIGGKTGTTNDSKDTWYSGYGPGMV 719
Cdd:COG5009 623 ------PDPAEQVIDPRTAYQMTSMLRGVV-----------QRGTGRRARALG-RDIAGKTGTTNDSKDAWFVGFTPDLV 684
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 720 ATVWVGFDNHnRNLGRtkansnlgknqitgAEAGAKTAEPAWVDFMGTALAGVPAERKEIPENIVRVRIDRETGLLTNKF 799
Cdd:COG5009 685 AGVWVGFDDP-RSLGR--------------GETGGRAALPIWIDFMKAALKDKPEKPFPVPEGIVTVRIDPKTGLLASPG 749
|
810 820 830 840
....*....|....*....|....*....|....*....|
gi 857938048 800 DSSSMFEYFEKGTEPTEYITErfndDIYSTSSGEAVEELF 839
Cdd:COG5009 750 DPDAIFEAFKPGTEPTESASE----DLGPDASEGTGEGLF 785
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
1-839 |
0e+00 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 1117.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 1 MILGVSTIFGFYYYVKPELPDVATLRDVELQTPMQVFSQDGKLISQFGEKRRNPVTYDEIPRHLVEALIATEDSRFYEHP 80
Cdd:PRK11636 15 ILLGAGSIYGLYRYIEPQLPDVATLKDVRLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEMVKAFIATEDSRFYEHH 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 81 GIDPIGITRAALVVAMSGSAKQGASTITQQLARNFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLGHRSY 160
Cdd:PRK11636 95 GVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAY 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 161 GFGAAARVYFGKDLPDLTLSEIATLAGMPKAPSTMNPIYSVERATNRRNVVLRRMLDEKYITQAEFDDARSEEIISKYHG 240
Cdd:PRK11636 175 GVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIVANYHA 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 241 AEIELSAPYVAEVARAWMVERYGEEAYTSGMKVYTTVDSKLQKAANQAAIKNLLGYDERHGYRGAEKVLWQTAQSAWDQE 320
Cdd:PRK11636 255 PEIAFSAPYLSEMVRQEMYNRYGENAYEDGYRVYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNK 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 321 QIVKHLKSQPTYGDLVPAVVTAVDSKSAQIWVKNQGEGTIEWQGMNWARKFLTDNRQGPAPSQAKEILAVGEQIWVRHea 400
Cdd:PRK11636 335 KITDTLKALPTYGPLLPAVVTSANPQEATAMLADGSSVALPMEGVRWARPYRSDTQQGPTPRKVTDVVQTGQQIWVRQ-- 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 401 vTGDEvseepteesataesetpivWRLSQVPNANTAFVAMNPNNGAVLSMVGGFNFVHNKFNRATQSIRQVGSGIKPFIY 480
Cdd:PRK11636 413 -VDDA-------------------WWLAQVPDVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLY 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 481 SAAIEKGLTLASLINDAPINQWDKSQGTAWRPKNSPPTYVGPTRLRIGLAQSKNVMAVRVLREVGLDDTRNYLTRFGFDI 560
Cdd:PRK11636 473 TAAMDKGLTLASMLNDVPISRWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPA 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 561 DEVPRSETIALGAGSLTPMKVAQGYSVFANGGYYVEPFYISRIETPFGETEFEATPKVVCKEdC---------------- 624
Cdd:PRK11636 553 QNIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEAKPKVACPE-Cdipviygdtqksnvle 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 625 -----------QQQMTSDPMAD-EFAEQDVDAK---VQYAPQVISEQNAFLVREMMYSNIWGGgdwsagTGWNGTGWRA- 688
Cdd:PRK11636 632 nddvenvatsqEQQNSSVPMPQlEQANQALVAQngaQEYAPHVINTPLAFLIKSALNTNIFGE------PGWMGTGWRAg 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 689 QPLKRRDIGGKTGTTNDSKDTWYSGYGPGMVATVWVGFDNHNRNLGRTKAnSNLGKNQITGAEAGAKTAEPAWVDFMGTA 768
Cdd:PRK11636 706 RDLKRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDHRRDLGRTTA-SGAIKDQISGYEGGAKSAQPAWDDYMKAA 784
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 857938048 769 LAGVPAERKEIPENIVRVRIDRETGLLTNkfDSSSMFEYFEKGTEPTEYITERFNDDIysTSSGEAvEELF 839
Cdd:PRK11636 785 LEGVPEQPLTPPPGIVTVNIDRSTGKLAN--GGNSREEYFIEGTQPTQQAVHEVGTTI--IDNGET-HELF 850
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
51-771 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 540.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 51 RRNPVTYDEIPRHLVEALIATEDSRFYEHPGIDPIGITRAALVVAMSGSAKQGASTITQQLARNFFLSNEKKIMRKIKEI 130
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 131 FIAIHIEQLLSKEEIMELYVNKIFLGHRSYGFGAAARVYFGKDLPDLTLSEIATLAGMPKAPSTMNPIYSVERATNRRNV 210
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 211 VLRRMLDEKYITQAEFDDARSEEIISK-YHGAEIELSAPYVAEVARAWMVERYGEEAYTSGMKVYTTVDSKLQKAANQAA 289
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYlQTKKSEQYKAPYFVDYVIQELEEEYGEELYTGGLKIYTTLDLDAQKAAEKVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 290 IKNLLGYDERHGYRgaekvlwqtaqsawdqeqivkhlksqptygdlvpavvtavdsksaqiwvknqgegtiewqgmnwar 369
Cdd:TIGR02074 241 NTGLRVAGRRDGDD------------------------------------------------------------------ 254
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 370 kfltdnrqgpapSQAkeilavgeqiwvrheavtgdevseepteesataesetpivwrlsqvpnantAFVAMNPNNGAVLS 449
Cdd:TIGR02074 255 ------------LQA---------------------------------------------------ALVAIDPDTGAVRA 271
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 450 MVGGFNFVHNKFNRATQSIRQVGSGIKPFIYSAAIEKGLTLASLINDAPInqwDKSQGTAWRPKNSPPTYVGPTRLRIGL 529
Cdd:TIGR02074 272 LVGGRDYGKSQFNRATQAKRQPGSTFKPFVYAAALEKGLTPATIVNDEPI---TYNGNGPWSPKNYGGGYRGNVTLRQAL 348
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 530 AQSKNVMAVRVLREVGLDDTRNYLTRFGFDIDEvPRSETIALGAGSLTPMKVAQGYSVFANGGYYVEPFYISRIETPFGE 609
Cdd:TIGR02074 349 AQSRNIPAVRLLQEVGLDKVVALAKRFGITSPL-DPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGK 427
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 610 TEFEATPKvvckedcqqqmtsdpmadefaeqdvdakvqyAPQVISEQNAFLVREMMYSNIwgggdwsagtgWNGTGWRAQ 689
Cdd:TIGR02074 428 VIYENKPK-------------------------------TTQVISPATAYIMTDMLKGVV-----------ESGTGRSAR 465
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 690 pLKRRDIGGKTGTTNDSKDTWYSGYGPGMVATVWVGFDNhNRNLGRTKansnlgknqitgaeAGAKTAEPAWVDFMGTAL 769
Cdd:TIGR02074 466 -LPGRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDD-KKTLGKSG--------------TGGGLAAPIWRDFMAEAL 529
|
..
gi 857938048 770 AG 771
Cdd:TIGR02074 530 KN 531
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
40-216 |
4.35e-88 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 276.71 E-value: 4.35e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 40 DGKLISQFGEKRRNPVTYDEIPRHLVEALIATEDSRFYEHPGIDPIGITRAALVVAMSGSAKQGASTITQQLARNFFLSN 119
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 120 EKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLGHRSYGFGAAARVYFGKDLPDLTLSEIATLAGMPKAPSTMNPIY 199
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 857938048 200 SVERATNRRNVVLRRML 216
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
1-839 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 1203.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 1 MILGVSTIFGFYYYVKPELPDVATLRDVELQTPMQVFSQDGKLISQFGEKRRNPVTYDEIPRHLVEALIATEDSRFYEHP 80
Cdd:COG5009 15 LLLGALAVAGLYLYLSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLLINAFLAAEDKRFYEHP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 81 GIDPIGITRAALVVAMSGSAKQGASTITQQLARNFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLGHRSY 160
Cdd:COG5009 95 GVDPIGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEILELYLNKIYLGHRAY 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 161 GFGAAARVYFGKDLPDLTLSEIATLAGMPKAPSTMNPIYSVERATNRRNVVLRRMLDEKYITQAEFDDARSEEIISKYHG 240
Cdd:COG5009 175 GVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEYEAAKAEPLTARYHG 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 241 AEIELSAPYVAEVARAWMVERYGEE-AYTSGMKVYTTVDSKLQKAANQAAIKNLLGYDERHGYRGAEKVLWQTAqsawdq 319
Cdd:COG5009 255 ASAEVDAPYFAEMVRRELVERYGEDaLYTGGLKVYTTLDPRLQEAAEKALRDGLLAYDRRHGYRGPEAHLDLAE------ 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 320 EQIVKHLKSQPTYGDLVPAVVTAVDSKSAQIWVKNQGEGTIEWQGMNWARKFLTDNRQGPAPSQAKEILAVGEQIWVRHE 399
Cdd:COG5009 329 EDWDEALAEVPDVGDLRPAVVLEVDDKSARVGLRDGETGTLPLEGLKWARPYINDNRRGPAPKSASDVLKPGDVIRVRPV 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 400 AVTGdevseepteesataesetpivWRLSQVPNANTAFVAMNPNNGAVLSMVGGFNFVHNKFNRATQSIRQVGSGIKPFI 479
Cdd:COG5009 409 ADGG---------------------WRLRQIPEVQGALVALDPHTGAVLALVGGFDFEQSKFNRATQAKRQPGSSFKPFV 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 480 YSAAIEKGLTLASLINDAPINQWDKSQGTAWRPKNSPPTYVGPTRLRIGLAQSKNVMAVRVLREVGLDDTRNYLTRFGFD 559
Cdd:COG5009 468 YAAALDNGYTPATIINDAPIVFDDGGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFGIY 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 560 iDEVPRSETIALGAGSLTPMKVAQGYSVFANGGYYVEPFYISRIETPFGETEFEATPKVVCkEDCQQQMTSDPMADEfae 639
Cdd:COG5009 548 -SKLPPNLSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADPARAC-EDCDAAEWDGAEPRL--- 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 640 qdvdakVQYAPQVISEQNAFLVREMMYSNIwgggdwsagtgWNGTGWRAQPLKrRDIGGKTGTTNDSKDTWYSGYGPGMV 719
Cdd:COG5009 623 ------PDPAEQVIDPRTAYQMTSMLRGVV-----------QRGTGRRARALG-RDIAGKTGTTNDSKDAWFVGFTPDLV 684
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 720 ATVWVGFDNHnRNLGRtkansnlgknqitgAEAGAKTAEPAWVDFMGTALAGVPAERKEIPENIVRVRIDRETGLLTNKF 799
Cdd:COG5009 685 AGVWVGFDDP-RSLGR--------------GETGGRAALPIWIDFMKAALKDKPEKPFPVPEGIVTVRIDPKTGLLASPG 749
|
810 820 830 840
....*....|....*....|....*....|....*....|
gi 857938048 800 DSSSMFEYFEKGTEPTEYITErfndDIYSTSSGEAVEELF 839
Cdd:COG5009 750 DPDAIFEAFKPGTEPTESASE----DLGPDASEGTGEGLF 785
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
1-839 |
0e+00 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 1117.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 1 MILGVSTIFGFYYYVKPELPDVATLRDVELQTPMQVFSQDGKLISQFGEKRRNPVTYDEIPRHLVEALIATEDSRFYEHP 80
Cdd:PRK11636 15 ILLGAGSIYGLYRYIEPQLPDVATLKDVRLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEMVKAFIATEDSRFYEHH 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 81 GIDPIGITRAALVVAMSGSAKQGASTITQQLARNFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLGHRSY 160
Cdd:PRK11636 95 GVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAY 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 161 GFGAAARVYFGKDLPDLTLSEIATLAGMPKAPSTMNPIYSVERATNRRNVVLRRMLDEKYITQAEFDDARSEEIISKYHG 240
Cdd:PRK11636 175 GVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIVANYHA 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 241 AEIELSAPYVAEVARAWMVERYGEEAYTSGMKVYTTVDSKLQKAANQAAIKNLLGYDERHGYRGAEKVLWQTAQSAWDQE 320
Cdd:PRK11636 255 PEIAFSAPYLSEMVRQEMYNRYGENAYEDGYRVYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNK 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 321 QIVKHLKSQPTYGDLVPAVVTAVDSKSAQIWVKNQGEGTIEWQGMNWARKFLTDNRQGPAPSQAKEILAVGEQIWVRHea 400
Cdd:PRK11636 335 KITDTLKALPTYGPLLPAVVTSANPQEATAMLADGSSVALPMEGVRWARPYRSDTQQGPTPRKVTDVVQTGQQIWVRQ-- 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 401 vTGDEvseepteesataesetpivWRLSQVPNANTAFVAMNPNNGAVLSMVGGFNFVHNKFNRATQSIRQVGSGIKPFIY 480
Cdd:PRK11636 413 -VDDA-------------------WWLAQVPDVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLY 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 481 SAAIEKGLTLASLINDAPINQWDKSQGTAWRPKNSPPTYVGPTRLRIGLAQSKNVMAVRVLREVGLDDTRNYLTRFGFDI 560
Cdd:PRK11636 473 TAAMDKGLTLASMLNDVPISRWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPA 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 561 DEVPRSETIALGAGSLTPMKVAQGYSVFANGGYYVEPFYISRIETPFGETEFEATPKVVCKEdC---------------- 624
Cdd:PRK11636 553 QNIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEAKPKVACPE-Cdipviygdtqksnvle 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 625 -----------QQQMTSDPMAD-EFAEQDVDAK---VQYAPQVISEQNAFLVREMMYSNIWGGgdwsagTGWNGTGWRA- 688
Cdd:PRK11636 632 nddvenvatsqEQQNSSVPMPQlEQANQALVAQngaQEYAPHVINTPLAFLIKSALNTNIFGE------PGWMGTGWRAg 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 689 QPLKRRDIGGKTGTTNDSKDTWYSGYGPGMVATVWVGFDNHNRNLGRTKAnSNLGKNQITGAEAGAKTAEPAWVDFMGTA 768
Cdd:PRK11636 706 RDLKRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDHRRDLGRTTA-SGAIKDQISGYEGGAKSAQPAWDDYMKAA 784
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 857938048 769 LAGVPAERKEIPENIVRVRIDRETGLLTNkfDSSSMFEYFEKGTEPTEYITERFNDDIysTSSGEAvEELF 839
Cdd:PRK11636 785 LEGVPEQPLTPPPGIVTVNIDRSTGKLAN--GGNSREEYFIEGTQPTQQAVHEVGTTI--IDNGET-HELF 850
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
1-786 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 610.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 1 MILGVSTIFGFYYYVKPELPDVATLRDVELQTPMQVFSQDGKLISQFGEKRRNPVTYDEIPRHLVEALIATEDSRFYEHP 80
Cdd:COG0744 23 AVLVLAALAGLVALYVADLPDPEELEDLALPQTSTIYDRDGTLIATLGDENREWVPLDQIPPHLKDAVVAIEDRRFYEHG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 81 GIDPIGITRAALVVAMSGSAKQGASTITQQLARNFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLGHRSY 160
Cdd:COG0744 103 GVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRGAY 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 161 GFGAAARVYFGKDLPDLTLSEIATLAGMPKAPSTMNPIYSVERATNRRNVVLRRMLDEKYITQAEFDDARSEEI-ISKYH 239
Cdd:COG0744 183 GIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLtLVPPP 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 240 GAEIELSAPYVAEVARAWMVERYGEEA-YTSGMKVYTTVDSKLQKAANQAAIKNLlgyderhgyrgaekvlwqtaqsawd 318
Cdd:COG0744 263 NGAAAGKYPYFVDYVRRELEELLGEDDlYRGGLKIYTTLDPKLQKAAEKAVKNVL------------------------- 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 319 qeqivkhlksqptygdlvpavvtavdsksaqiwvknqgegtiewqgmnwarkfltdNRQGPAPSQAkeilavgeqiwvrh 398
Cdd:COG0744 318 --------------------------------------------------------PEGKPGGLQA-------------- 327
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 399 eavtgdevseepteesataesetpivwrlsqvpnantAFVAMNPNNGAVLSMVGGFNFVHNKFNRATQSIRQVGSGIKPF 478
Cdd:COG0744 328 -------------------------------------ALVVVDPKTGEVLAMVGGRDYGKSQFNRATQAKRQPGSTFKPF 370
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 479 IYSAAIEKGLTLASLINDAPInqwdKSQGTAWRPKNSPPTYVGPTRLRIGLAQSKNVMAVRVLREVGLDDTRNYLTRFGF 558
Cdd:COG0744 371 VYAAALEQGYTPATTVDDEPV----TFPGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGI 446
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 559 DiDEVPRSETIALGAGSLTPMKVAQGYSVFANGGYYVEPFYISRIETPFGETEFEATPKVVckedcqqqmtsdpmadefa 638
Cdd:COG0744 447 T-SPLDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCE------------------- 506
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 639 eqdvdakvqyapQVISEQNAFLVREMMysniwgggdwsAGTGWNGTGWRAQpLKRRDIGGKTGTTNDSKDTWYSGYGPGM 718
Cdd:COG0744 507 ------------QVISPEVAYLMTDML-----------QDVVTSGTGRAAR-LPGRPVAGKTGTTNDNRDAWFVGYTPQL 562
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 857938048 719 VATVWVGFDNhnrnlgrtkansnlgkNQITGAEAGAKTAEPAWVDFMGTALAGVPAERKEIPENIVRV 786
Cdd:COG0744 563 VTAVWVGNDD----------------NSPMGYVTGGSLPAPIWRDFMEAALEGLPVEDFPKPSGVVRI 614
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
51-771 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 540.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 51 RRNPVTYDEIPRHLVEALIATEDSRFYEHPGIDPIGITRAALVVAMSGSAKQGASTITQQLARNFFLSNEKKIMRKIKEI 130
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 131 FIAIHIEQLLSKEEIMELYVNKIFLGHRSYGFGAAARVYFGKDLPDLTLSEIATLAGMPKAPSTMNPIYSVERATNRRNV 210
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 211 VLRRMLDEKYITQAEFDDARSEEIISK-YHGAEIELSAPYVAEVARAWMVERYGEEAYTSGMKVYTTVDSKLQKAANQAA 289
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYlQTKKSEQYKAPYFVDYVIQELEEEYGEELYTGGLKIYTTLDLDAQKAAEKVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 290 IKNLLGYDERHGYRgaekvlwqtaqsawdqeqivkhlksqptygdlvpavvtavdsksaqiwvknqgegtiewqgmnwar 369
Cdd:TIGR02074 241 NTGLRVAGRRDGDD------------------------------------------------------------------ 254
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 370 kfltdnrqgpapSQAkeilavgeqiwvrheavtgdevseepteesataesetpivwrlsqvpnantAFVAMNPNNGAVLS 449
Cdd:TIGR02074 255 ------------LQA---------------------------------------------------ALVAIDPDTGAVRA 271
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 450 MVGGFNFVHNKFNRATQSIRQVGSGIKPFIYSAAIEKGLTLASLINDAPInqwDKSQGTAWRPKNSPPTYVGPTRLRIGL 529
Cdd:TIGR02074 272 LVGGRDYGKSQFNRATQAKRQPGSTFKPFVYAAALEKGLTPATIVNDEPI---TYNGNGPWSPKNYGGGYRGNVTLRQAL 348
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 530 AQSKNVMAVRVLREVGLDDTRNYLTRFGFDIDEvPRSETIALGAGSLTPMKVAQGYSVFANGGYYVEPFYISRIETPFGE 609
Cdd:TIGR02074 349 AQSRNIPAVRLLQEVGLDKVVALAKRFGITSPL-DPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGK 427
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 610 TEFEATPKvvckedcqqqmtsdpmadefaeqdvdakvqyAPQVISEQNAFLVREMMYSNIwgggdwsagtgWNGTGWRAQ 689
Cdd:TIGR02074 428 VIYENKPK-------------------------------TTQVISPATAYIMTDMLKGVV-----------ESGTGRSAR 465
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 690 pLKRRDIGGKTGTTNDSKDTWYSGYGPGMVATVWVGFDNhNRNLGRTKansnlgknqitgaeAGAKTAEPAWVDFMGTAL 769
Cdd:TIGR02074 466 -LPGRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDD-KKTLGKSG--------------TGGGLAAPIWRDFMAEAL 529
|
..
gi 857938048 770 AG 771
Cdd:TIGR02074 530 KN 531
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
22-805 |
1.19e-106 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 344.40 E-value: 1.19e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 22 VATLRDVELQTPMQVFSQDGKLI----SQFGEKRRnPVTYDEIPRHLVEALIATEDSRFYEHPGIDPIGITRAALVVAMS 97
Cdd:TIGR02071 114 LSKIENLDNNKEFGFFRLDPKLIamlySPNGEQRL-FVPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTA 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 98 GSAKQGASTITQQLARNFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLGHRS----YGFGAAARVYFGKD 173
Cdd:TIGR02071 193 GRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALILDARYSKDRILELYLNEVYLGQSGddaiHGFPLASQYYFGRP 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 174 LPDLTLSEIATLAGMPKAPSTMNPIYSVERATNRRNVVLRRMLDEKYITQAEFDDA--------RSEEIISKYhgaeiel 245
Cdd:TIGR02071 273 LGELSLDQVALLVGMVKGPSYYNPWRNPDRALERRNLVLRLLQEQKIIDDEEYDMLsarplgvqKKGGIISRQ------- 345
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 246 saPYVAEVARAWMVERYGEEAYT-SGMKVYTTVDSKLQKAANQaaiknllgyderhgyrgaekvlwqtaqsawdqeqivk 324
Cdd:TIGR02071 346 --PAFLQLVRRELRQKLGDKVKDlSGLRIFTTLDPVSQSAAEQ------------------------------------- 386
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 325 hlksqptygdlvpavvtavdsksaqiwvknqgegtiewqgmnwarkfltdnrqgpapsqakeilAVGEQIwvrheavtgd 404
Cdd:TIGR02071 387 ----------------------------------------------------------------AVQETI---------- 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 405 evseepteesataesetPIVWRLSQVPNANTAFVAMNPNNGAVLSMVGGFNFVHNKFNRATQSIRQVGSGIKPFIYSAAI 484
Cdd:TIGR02071 393 -----------------PALKKKKKLPDLEAAMVVTDRFTGEVRAMVGGSDPQFAGFNRALQARRQIGSLVKPAVYLTAL 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 485 E--KGLTLASLINDAPINqWDKSQGTAWRPKNSPPTYVGPTRLRIGLAQSKNVMAVRVLREVGLDDTRNYLTRFGFDIDE 562
Cdd:TIGR02071 456 SqpDKYRLNTWIEDQPLS-IKLSNGQVWSPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQTWNKLGINKDE 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 563 VPRSETIALGAGSLTPMKVAQGYSVFANGGYYVEPFYISRIETPFGETEFEATPKvvckedcqqqmtsdpmadefAEQDV 642
Cdd:TIGR02071 535 IPPVPSMLLGAINLTPYEVAQLYQTIASGGNRAPLSAVRSVLDEDGKVLYQSDPQ--------------------AEQAV 594
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 643 DAKVQYAPQVISEQnafLVREmmysniwgggdwsagtgwnGTGWRAQP-LKRRDIGGKTGTTNDSKDTWYSGYGPGMVAT 721
Cdd:TIGR02071 595 PSQAAYLTLYAMQQ---VVQR-------------------GTARSLGAdFPSLSLAGKTGTTNDNRDSWFAGIDGKEVTI 652
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 722 VWVGFDNHnrnlgrtkansnlGKNQITGAeAGAKTaepAWVDFMG----TALAGVPaerkeiPENIVRVRIDRETGLLTn 797
Cdd:TIGR02071 653 IWLGRDDN-------------GPTKLTGA-SGALQ---VYARYLSyqtpEPLLLVP------PEGIDWFGVDPQGNGGC- 708
|
....*...
gi 857938048 798 KFDSSSMF 805
Cdd:TIGR02071 709 KANCPGAR 716
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
2-816 |
5.31e-94 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 311.77 E-value: 5.31e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 2 ILGVSTIFGFYYYVKPELPDVATLRdvelqtpmQVFSQDGKLISQF---GEKRRNPVTYDEIPRHLVEALIATEDSRFYE 78
Cdd:COG4953 20 LLALALWALDRLFPLPLLFAVPYST--------VVLDRDGTLLRAFlaaDGQWRLPVPLDEVSPRYLQALLAYEDRRFYY 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 79 HPGIDPIGITRAALVVAMSGSAKQGASTITQQLARnffLS--NEKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLG 156
Cdd:COG4953 92 HPGVNPLALLRAAWQNLRSGRIVSGGSTLTMQVAR---LLepRPRTLSGKLRQILRALQLERRYSKDEILELYLNLAPYG 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 157 HRSYGFGAAARVYFGKDLPDLTLSEIATLAGMPKAPSTMNPIYSVERATNRRNVVLRRMLDEKYITQAEFDDARSEEIIS 236
Cdd:COG4953 169 GNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLAEAGVIDAEEAALALLEPVPA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 237 KYHGAEIElsAPYVAEVARAwmverygeeAYTSGMKVYTTVDSKLQKAAnqaaiknllgyderhgyrgaekvlwqtaqsa 316
Cdd:COG4953 249 RRRPLPQL--APHLARRLLR---------QLPGGTRIRTTLDAGLQRRL------------------------------- 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 317 wdqEQIVKhlksqptygdlvpavvtavdsksaqiwvknqgegtiewqgmNWARkfltdnrqgpapsqakeilavgeqiwv 396
Cdd:COG4953 287 ---ERLVR-----------------------------------------RYVR--------------------------- 295
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 397 rheavtgdevseepteesataesetpivwRLSQVPNANTAFVAMNPNNGAVLSMVGG---FNFVHNKFNRATQSIRQVGS 473
Cdd:COG4953 296 -----------------------------RLKQNGIHNAAVLVVDNRTGEVLAYVGSadfFDASRQGQVDMVRALRSPGS 346
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 474 GIKPFIYSAAIEKGLTL-ASLINDAPINQWDksqgtaWRPKNSPPTYVGPTRLRIGLAQSKNVMAVRVLREVGLDDTRNY 552
Cdd:COG4953 347 TLKPFLYGLALDQGLIHpETLLADVPTSFGG------YRPENFDGTFQGPVSAREALARSLNIPAVRLLEALGPARFYAR 420
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 553 LTRFGFDiDEVPRSET----IALGAGSLTPMKVAQGYSVFANGGYYVEPFYIsrietpfgetefeatpkvvckedcqqqm 628
Cdd:COG4953 421 LRRAGLR-LLLPPAEHyglsLILGGAEVTLEELVGLYAALARGGEARPLRLL---------------------------- 471
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 629 TSDPMADEfaeqdvdakvqyaPQVISEQNAFLVREMMysniwgggdwsAGTG--WNGTGWRAQPLKRRdIGGKTGTTNDS 706
Cdd:COG4953 472 AGEPASPG-------------RRLLSPGAAWLVRDIL-----------SDVPrpDGAFGWRALDSPPP-IAWKTGTSYGF 526
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 707 KDTWYSGYGPGMVATVWVG-FDNHNRnlgrtkansnlgkNQITGAEAGAktaePAWVDFMGTALAGVPAERKEIPENIVR 785
Cdd:COG4953 527 RDAWAVGFTGRYTVGVWVGnPDGTPV-------------PGLTGAEAAA----PLLFDIFDLLPASRWPLPFPPPAGLLR 589
|
810 820 830
....*....|....*....|....*....|.
gi 857938048 786 VRIDRETGLLTNKFDSSSMFEYFEKGTEPTE 816
Cdd:COG4953 590 VEVCAPSGLLAGPNCPQRVTEWFIPGTSPPT 620
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
40-216 |
4.35e-88 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 276.71 E-value: 4.35e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 40 DGKLISQFGEKRRNPVTYDEIPRHLVEALIATEDSRFYEHPGIDPIGITRAALVVAMSGSAKQGASTITQQLARNFFLSN 119
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 120 EKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLGHRSYGFGAAARVYFGKDLPDLTLSEIATLAGMPKAPSTMNPIY 199
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 857938048 200 SVERATNRRNVVLRRML 216
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
36-819 |
8.33e-68 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 239.24 E-value: 8.33e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 36 VFSQDGKLISQF---GEKRRNPVTYDEIPRHLVEALIATEDSRFYEHPGIDPIGITRAALVVAMSGSAKQGASTITQQLA 112
Cdd:TIGR02073 14 VLDRHGTLLRALlanDGQWRLPVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTNGRRVSGGSTLTMQLA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 113 RNFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLGHRSYGFGAAARVYFGKDLPDLTLSEIATLAGMPKAP 192
Cdd:TIGR02073 94 RLLDPELSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSLAEAALLAALPQAP 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 193 STMNPIYSVERATNRRNVVLRRMLDEKYITQAEFDDARSEEIISKYHgaEIELSAPYVA-EVARAwmverYGEEAYTsgm 271
Cdd:TIGR02073 174 SARRLDRLPKAAKAARDRLLDRMVEQGPDDSEQVALAALEPLPALPE--PLPQLAPHFAlKLLRA-----RPEIASV--- 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 272 kVYTTVDSKLQKaanqaaiknllgyderhgyrgaekvlwqtaqsawdqeqivkhlksqptygdlvpavvtavdsksaqiw 351
Cdd:TIGR02073 244 -IVSTLDADLQR-------------------------------------------------------------------- 254
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 352 vknqgegTIEWQGMNWARKFLTDNRQgpapsqakeilavgeqiwvrheavtgdevseepteesataesetpivwrlsqvp 431
Cdd:TIGR02073 255 -------RLEELARRYLSALRPRGIS------------------------------------------------------ 273
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 432 naNTAFVAMNPNNGAVLSMVGGFNFvhnkFNR-------ATQSIRQVGSGIKPFIYSAAIEKGLTLA-SLINDAPINQwd 503
Cdd:TIGR02073 274 --NLAILVVDNRSGAVLAYVGSADF----FDDsnsgqvdGVRAPRSPGSTLKPFLYALALDDGLLHPdSLLKDVPLRF-- 345
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 504 ksqgTAWRPKNSPPTYVGPTRLRIGLAQSKNVMAVRVLREVGLDDTRNYLTRFGFDIdevPRSE------TIALGAGSLT 577
Cdd:TIGR02073 346 ----GDYAPENFDKTFHGPVPAREALARSLNIPAVRLLERVGPPRFADFLRQAGLNL---LKPKsdyyglSLALGGAEIT 418
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 578 PMKVAQGYSVFANGGYYVEPfyisrietpfgetefeatpkvvckedcqqQMTSdpmadefaeqdVDAKVQYAPQVISEQN 657
Cdd:TIGR02073 419 LQDLANLYAMLANQGLSGPL-----------------------------RFLQ-----------TDAKRPERERLLSPGA 458
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 658 AFLVREMMYSNIW-GGGDWSAGTgwnGTGWRaqplkrrdIGGKTGTTNDSKDTWYSGYGPGMVATVWVG-FDNhnrnlgr 735
Cdd:TIGR02073 459 AWIVLDILKDRPRpDDTLPLSAL---PTRLP--------LAWKTGTSYGFRDAWAAGVSGRYTIGVWVGnFDG------- 520
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 736 tKANSNLgknqitgaeAGAKTAEPAWVDFMGTALAGVPAERkeiPENIVRVRIDRETGLLTNKFDSSSMFEYFEKGTEPT 815
Cdd:TIGR02073 521 -KPNPGF---------FGAAAAAPLLFDILDALQASEASTL---PRPLKEVPGCLVLGNLPILPCPEQISTWFLPGGSPP 587
|
....
gi 857938048 816 EYIT 819
Cdd:TIGR02073 588 TLSE 591
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
22-737 |
4.50e-65 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 233.51 E-value: 4.50e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 22 VATLRDVELQTPMQVFSQDGKLISQF----GEKRRNpVTYDEIPRHLVEALIATEDSRFYEHPGIDPIGITRAALVVAMS 97
Cdd:PRK09506 178 LATIVNLDNNRQFGFFRLDPRLITMLqspnGEQRLF-VPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTA 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 98 GSAKQGASTITQQLARNFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLGHRS----YGFGAAARVYFGKD 173
Cdd:PRK09506 257 GRTVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALIMDARYSKDRILELYLNEVYLGQSGddqiRGFPLASLYYFGRP 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 174 LPDLTLSEIATLAGMPKAPSTMNPIYSVERATNRRNVVLRRMLDEKYITQAEFD--DARSEEIISKyhgAEIELSAPYVA 251
Cdd:PRK09506 337 VEELSLDQQALLVGMVKGASLYNPWRNPKLALERRNLVLRLLQQQQIIDQELYDmlSARPLGVQPK---GGVISPQPAFM 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 252 EVARAWMVERYGEEAYT-SGMKVYTTVDSKLQKAANQAAiknllgyderhgyrgaekvlwqtaqsawdqEQIVKHLKSQP 330
Cdd:PRK09506 414 QMVRQELQAKLGDKVKDlSGVKIFTTLDPVSQDAAEKAV------------------------------EEGIPALKKQR 463
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 331 TYGDLVPAVVtavdsksaqiwvknqgegtiewqgmnwarkfltdnrqgpapsqakeilavgeqiwvrheavtgdevseep 410
Cdd:PRK09506 464 KLSDLETAMV---------------------------------------------------------------------- 473
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 411 teesataesetpIVWRLSqvpnantafvamnpnnGAVLSMVGGFNFVHNKFNRATQSIRQVGSGIKPFIYSAAIEKGLT- 489
Cdd:PRK09506 474 ------------VVDRFS----------------GEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQPDKy 525
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 490 -LASLINDAPINqWDKSQGTAWRPKNSPPTYVGPTRLRIGLAQSKNVMAVRVLREVGLDDTRNYLTRFGFDIDEVPRSET 568
Cdd:PRK09506 526 rLNTWIADAPIS-LRQPNGQVWSPQNDDRRFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDQLNPVPA 604
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 569 IALGAGSLTPMKVAQGYSVFANGGYYvepfyisrietpfgetefeATPKVVCKedcqqqmtsdpmadEFAEqdvDAKVQY 648
Cdd:PRK09506 605 MLLGALNLTPIEVAQAFQTIASGGNR-------------------APLSALRS--------------VIAE---DGKVLY 648
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 649 -----APQVISEQNAFLVREMMYSNIwgggdwSAGTGwngtgwRAQPLK--RRDIGGKTGTTNDSKDTWYSGYGPGMVAT 721
Cdd:PRK09506 649 qsfpqAERAVPAQAAYLTLYTMQQVV------QRGTG------RQLGAKypNLHLAGKTGTTNDLVDSWFAGIDGKEVTI 716
|
730
....*....|....*.
gi 857938048 722 VWVGFDNHnrnlGRTK 737
Cdd:PRK09506 717 TWVGRDNN----QPTK 728
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
36-747 |
8.83e-65 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 231.66 E-value: 8.83e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 36 VFSQDGKLISQF----GEKRRNpVTYDEIPRHLVEALIATEDSRFYEHPGIDPIGITRAALVVAMSGSAKQGASTITQQL 111
Cdd:PRK14850 138 FLRLDPKLIAMLyspeGKKRLF-IPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTIQGGSTLTQQL 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 112 ARNFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLGH----RSYGFGAAARVYFGKDLPDLTLSEIATLAG 187
Cdd:PRK14850 217 VKNLFLTNTRSLWRKINEIYMALILDRFYSKDRILELYLNEVYLGQdgneQIRGFPLASIYYFGRPINELNLDQYALLVG 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 188 MPKAPSTMNPIYSVERATNRRNVVLRRMLDEKYITQAEFDDARSEEIISKYHGAEIELSAPYVAEVARAWMVERYGEEAY 267
Cdd:PRK14850 297 MVKGASLYNPWTNPNLTLKRRNLVLFLLYKQKVITRKLYKDLCSRPLNVQSKGNIISSHPAFIQLVCEEFHKKIHYPFKN 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 268 TSGMKVYTTVDSKLQKAANQAAiknllgydeRHGyrgaekvlwqtaqsawdqeqiVKHLKSQPTYGDLVPAVVtavdsks 347
Cdd:PRK14850 377 FSGTKIFTTLDYISQNAAEQAV---------KIG---------------------IPILKRKKRLKDLEVAMV------- 419
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 348 aqiwvknqgegtiewqgmnwarkfltdnrqgpapsqakeilavgeqiwvrheavtgdevseepteesataesetpIVWRL 427
Cdd:PRK14850 420 ---------------------------------------------------------------------------IIDRF 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 428 SqvpnantafvamnpnnGAVLSMVGGFNFVHNKFNRATQSIRQVGSGIKPFIYSAAIEK--GLTLASLINDAPInQWDKS 505
Cdd:PRK14850 425 S----------------GEVRALIGSSKPEFNGYNRALKARRSIGSLSKPITYLTALSQpeKYHLNTWISDTPI-SIKLD 487
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 506 QGTAWRPKNSPPTYVGPTRLRIGLAQSKNVMAVRVLREVGLDDTRNYLTRFGFDIDEVPRSETIALGAGSLTPMKVAQGY 585
Cdd:PRK14850 488 NGQYWTPKNNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWILLGISSNYITPLPSISLGAINLTPMEVAQVF 567
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 586 SVFANGGYYVEPFYISRIETPFGETEFEATPKVVckedcqqqmtsdpmadefaeqdvdakvqyapQVISEQNAFLVREMM 665
Cdd:PRK14850 568 QIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSK-------------------------------HVESSQASYLTLYAM 616
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 666 YSNIWGGGDWSAGTGWngtgwraqplKRRDIGGKTGTTNDSKDTWYSGYGPGMVATVWVGFDNHnrnlGRTKANSNLGKN 745
Cdd:PRK14850 617 QQVVKSGTAKSLGTIF----------KEFSLAGKTGTTNNLVDSWFVGIDGKQVVITWIGRDNN----HTTKLYGSSGAM 682
|
..
gi 857938048 746 QI 747
Cdd:PRK14850 683 KI 684
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
49-232 |
3.62e-38 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 142.25 E-value: 3.62e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 49 EKRRNPVTYDEIPRHLVEALIATEDSRFYEHPGIDPIGITRAaLVVAMSGSAKQGASTITQQLARNFFLSNEKKIMRKIK 128
Cdd:PRK13481 42 ENKSSFVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRA-LFSTISDRDVQGGSTITQQVVKNYFYDNERSFTRKVK 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 129 EIFIAIHIEQLLSKEEIMELYVNKIFLGHRSYGFGAAARVYFG-------KDLPDLTLSEIATLAGMPKAPSTMNPIYSV 201
Cdd:PRK13481 121 ELFVAHRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFGttvnknsTTMSHITVLQSAILASKVNAPSVYNINDMS 200
|
170 180 190
....*....|....*....|....*....|.
gi 857938048 202 ERATNRRNVVLRRMLDEKYITQAEFDDARSE 232
Cdd:PRK13481 201 ENFTQRVSTNLEKMKQQNYINETQYQQAMSQ 231
|
|
| PCB_OB |
pfam17092 |
Penicillin-binding protein OB-like domain; |
302-433 |
1.16e-35 |
|
Penicillin-binding protein OB-like domain;
Pssm-ID: 465343 [Multi-domain] Cd Length: 111 Bit Score: 130.83 E-value: 1.16e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 302 YRGAEKVLWQTAQSAWDQEQIVKHLKSQPTYGDLVPAVVTAVDSKSAQIWVKNQGEGTIEWQGMNWARKFLTDNRQGPAP 381
Cdd:pfam17092 1 YRGPEAHLDLPADWAERLAAIDEALADLPDVGGLRPAVVLSVSPKSARVGLRDGETGTIPGEGLRWARPYLSDKRQGPAP 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 857938048 382 SQAKEILAVGEQIWVRHeavTGDevseepteesataesetpIVWRLSQVPNA 433
Cdd:pfam17092 81 KSASDVLKPGDVIRVRP---NGD------------------GGWRLRQVPEV 111
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
51-215 |
3.29e-33 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 127.58 E-value: 3.29e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 51 RRNPVTYDEIPRHLVEALIATEDSRFYEHPGIDPIGITRAALVVAMSGSAKQGASTITQQLARNFFLSNEKKIMRKIKEI 130
Cdd:TIGR02070 54 QHRWRPYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEA 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 131 FIAIHIEQLLSKEEIMELYVNKIFLGHRSYGFGAAARVYFGKDLPDLTLSEIATLAGMPKAPSTMNPIYSVERATNRRNV 210
Cdd:TIGR02070 134 WATWMLETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDENRPGPYVRRKATW 213
|
....*
gi 857938048 211 VLRRM 215
Cdd:TIGR02070 214 ILKQM 218
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
36-234 |
1.21e-32 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 135.60 E-value: 1.21e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 36 VFSQDGKLISQFGEKR---RNPVTYDEI-PRHLvEALIATEDSRFYEHPGIDPIGITRAALVVAMSGSAKQGASTITQQL 111
Cdd:PRK11240 43 VVAEDGTPLWRFADADgiwRYPVTIEDVsPRYL-EALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQV 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 112 ARnFFLSNEKKIMRKIKEIFIAIHIEQLLSKEEIMELYVNKIFLGHRSYGFGAAARVYFGKDLPDLTLSEIATLAGMPKA 191
Cdd:PRK11240 122 AR-LLDPHPRTFGGKIRQLWRALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQA 200
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 857938048 192 PSTMNPIYSVERATNRRNVVLRRMLDEKYITQAEFDDARSEEI 234
Cdd:PRK11240 201 PSRLRPDRWPERAEAARNKVLERMAEQGVWSAEQVKESREEPV 243
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
436-716 |
4.99e-28 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 119.93 E-value: 4.99e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 436 AFVAMNPNNGAVLSMVG--GFN---FVHNK----FNRATQSIRQVGSGIKPFIYSAAIEKGL-TLASLIND--------A 497
Cdd:COG0768 250 AVVVMDPKTGEILAMASypSFDpnlFVGGPdeplRNRAVQGTYEPGSTFKPFTAAAALEEGViTPDTTFDCpgyyrvggR 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 498 PINQWDKSqGTawrpknspptyvGPTRLRIGLAQSKNVMAVRVLREVGLDDTRNYLTRFGF----DID---E----VPRS 566
Cdd:COG0768 330 TIRDWDRG-GH------------GTLTLTEALAKSSNVGFYKLALRLGIDKLYDYLKKFGLgqktGIDlpgEasglLPSP 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 567 E--------TIALGAG-SLTPMKVAQGYSVFANGGYYVEPFYISRIETPFGETEFEATPKVvckedcqqqmtsdpmadef 637
Cdd:COG0768 397 KrwypgetaTMSIGQGlSVTPLQLAQAYAAIANGGVLVKPHLVKEIVDPDGEVVKEEPEVL------------------- 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 638 aeqdvdakvqyaPQVISEQNAFLVREMMYSNIwgggdwsagTGWNGTGWRAQPLKRRdIGGKTGT-----------TNDS 706
Cdd:COG0768 458 ------------RRVISPETAETVREGMEGVV---------NEPGGTARRAAIPGYR-VAGKTGTaqvvdignggyYKGR 515
|
330
....*....|
gi 857938048 707 KDTWYSGYGP 716
Cdd:COG0768 516 HIASFVGFAP 525
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
436-716 |
2.12e-27 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 113.28 E-value: 2.12e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 436 AFVAMNPNNGAVLSMVGGFNFVHNKF-----NRATQSIRQVGSGIKPFIYSAAIEKG-LTLASLINDAPINQwdkSQGTA 509
Cdd:pfam00905 2 SAVVLDPKTGEVLAMVGKPSYDPNGFigplrNRAVTSRYEPGSTFKPFTALAALDNGvLKPDETIFDWPGKQ---QGGKS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 510 WRPKNSppTYVGPTRLRIGLAQSKNVMAVRVLREVGLDDTRNYLTRFGFDID-----------EVPRSE----TIALGAG 574
Cdd:pfam00905 79 IGDWNQ--DQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYGNKtgiglpgenagYLTPYWlegaTASFGIG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 575 -SLTPMKVAQGYSVFANGGYYVEPFYISRIetpfgetEFEATPKVVCKedcqqqmtsdpmadefaeqdvdakvqyapQVI 653
Cdd:pfam00905 157 lTITPLQQAQAYAAIANGGKLVPPHLVKSI-------EDKVDPKVLNK-----------------------------LPI 200
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 857938048 654 SEQNAFLVREMMYsniwgggdwSAGTGWNGTGWRAQPLkrRDIGGKTGTT-----------NDSKDTWYSGYGP 716
Cdd:pfam00905 201 SKSTAEKVKDMLR---------LVVNDGTGTGTAAVPG--YKVAGKTGTAqvagpkgggyyDGAQIGWFVGYAP 263
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
436-702 |
1.34e-15 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 81.03 E-value: 1.34e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 436 AFVAMNPNNGAVLSMVG--GFN---FVH------------NK----FNRATQSIRQVGSGIKPFIYSAAIEKGLTLASL- 493
Cdd:TIGR03423 250 AVVVMDPRTGEILAMVStpSFDpnlFVDgisskdykallnDPdrplLNRAIQGVYPPGSTFKPVVALAALEEGVITPETr 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 494 INDA--------PINQWDKSqGtawrpknspptyVGPTRLRIGLAQSKNVMAVRVLREVGLDDTRNYLTRFGF------D 559
Cdd:TIGR03423 330 IYCPgyfqlggrRFRCWKRG-G------------HGRVDLRKAIEESCDVYFYQLALRLGIDKIAEYAKRFGFgqktgiD 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 560 IDE-----VP--------------RSETIALGAG----SLTPMKVAQGYSVFANGGYYVEPFYISRIETPFGETEFEATP 616
Cdd:TIGR03423 397 LPGeksglVPsrewkrkrfgqpwyPGDTLNVSIGqgyvLVTPLQLAVATAALANGGKLYKPHLVKSIEDPDGGVVRRTEP 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857938048 617 KVVckedcqqqmtsdpmadefaeqdvdakvqyAPQVISEQNAFLVREMMYSNIwgggdwsagTGWNGTGWRAQPLKRRDI 696
Cdd:TIGR03423 477 EVL-----------------------------RPLPISPENLDVVREGMRDVV---------NGPGGTARRARLGLPYKM 518
|
....*.
gi 857938048 697 GGKTGT 702
Cdd:TIGR03423 519 AGKTGT 524
|
|
| |
