|
Name |
Accession |
Description |
Interval |
E-value |
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1013 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 899.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 1 MKLPEICIKHPVFASVLSITIVLFGLLSFQKLSIQYFPEHKTPSATVTAAINGASAEFMSRNVADKLITAATGLDSVKTM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 81 TTDCQEGTCNLKIIFEDDIN-DVeytsLMNNLRSSVEAI-GDFPPSMtDKPTVTDDSSDTSMpsnIITFVNTGK-MSKQD 157
Cdd:COG0841 81 TSTSSEGSSSITVEFELGTDiDE----ALVDVQNAVDRArSDLPEDV-EPPGVTKVNPSDFP---VMVLALSSDdLDELE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 158 MYDYISQQVVPQFKHIQGVGGIWgPYGGSEKAVRVWLQPDRMMALNMSASDVVGTLSSYNATFTAGTIKGLVRDFSINPV 237
Cdd:COG0841 153 LSDYAERNIKDRLERVPGVGQVQ-IFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTN 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 238 NQVTSVDDVRDLVVRVDDGKIIRIGDIAEVKMGEENLTpSILRVDDNLAMSIQVLPLKSENPVTVANKVKKQIDLIQPQL 317
Cdd:COG0841 232 GRLKTPEEFENIVIRTNDGSVVRLGDVARVEDGAEDYR-SIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 318 PEGIEMKMVYNQADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVIGVFAVMHLLGFSINVLTILA 397
Cdd:COG0841 311 PEGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFA 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 398 IILAIGLVVDDAIVVAENCYRHIEEGETPFNAAIKGCREIVFPVIAMTLTLAVVYLPIGLMAGLTADLFRQFAFTLAAAV 477
Cdd:COG0841 391 LVLAIGIVVDDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIAL 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 478 IISGFVALTLSPMMSAYLMKPVSTPAK--WYQKVDAKLNVLSDLYTKELGKWFDRKALMSGIALVLIALSALAVWKMPQV 555
Cdd:COG0841 471 LISLFVALTLTPALCARLLKPHPKGKKgrFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTE 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 556 LLPTEDTGFVEVTSTPPTGVGRQYHLDNNAQLNSVFKGDSSVEANLSYI---EGTPTNH-----VLLKPWGERGQSADEL 627
Cdd:COG0841 551 FFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVgfsGGGSGSNsgtifVTLKPWDERDRSADEI 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 628 VNEfIAKAQSSVSayGMSFKVRSADNLNIATNMILELTTVNRDTTVLSETASEVVKALEDYEGVTNIKNSMLRDQLRYDL 707
Cdd:COG0841 631 IAR-LREKLAKIP--GARVFVFQPPAGGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPELQL 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 708 SIDRNAIVLSGVDYGNVTNALSTFLGSVKAADLQaDDGYTYPIQVQVNRSDLGDFKVLDKLYVDSQSGQRLPLSQFVSIK 787
Cdd:COG0841 708 DIDREKAAALGVTVADVASTLRAALGGRYVNDFN-RGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPLSSVATIE 786
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 788 QVTSESNFKTFMGKDSAEITADLMPGYMASDVKAYIDDTVPSLLKPAQ-SYEFNGIVKDLVDSTAGAQVLFVLALIFIFL 866
Cdd:COG0841 787 EGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAELKLPPGvSIEFTGQAEEEQESFSSLGLAFLLALLLVYL 866
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 867 ILAAQFESFVDPMIILLTVPLCIVGAILTLSVFGQSLNIYSKIGLLTLVGLVTKHGILLVEFANEKRKSGASAKEAAISS 946
Cdd:COG0841 867 VLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSLREAILEA 946
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 857909416 947 ARSRLRPILMTSLTMILGSLPLALADGPGSLGRINIGLVLVGGLTAGTFFSLFLVPVAYVGMANLKQ 1013
Cdd:COG0841 947 ARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLRR 1013
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
7-1005 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 736.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 7 CIKHPVFASVLSITIVLFGLLSFQKLSIQYFPEHKTPSATVTAAINGASAEFMSRNVADKLITAATGLDSVKTMTTDCQE 86
Cdd:NF033617 4 FIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 87 GTCNLKIIFEDDINdveYTSLMNNLRSSVEAIGDFPPSMTDKPTVTDDSSDTSMPSNIITFVNTGkMSKQDMYDYISQQV 166
Cdd:NF033617 84 GYSTITLQFRLGTD---LDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTPIMYIGLTSEE-MPRGQLTDYAERVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 167 VPQFKHIQGVGGIwGPYGGSEKAVRVWLQPDRMMALNMSASDVVGTLSSYNATFTAGTIKGLVRDFSINPVNQVTSVDDV 246
Cdd:NF033617 160 APKLSQINGVGSV-DVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDY 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 247 RDLVVRV-DDGKIIRIGDIAEVKMGEENlTPSILRVDDNLAMSIQVLPLKSENPVTVANKVKKQIDLIQPQLPEGIEMKM 325
Cdd:NF033617 239 EDLVIKYaDNGAPVRLGDVATVELGAEN-VRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 326 VYNQADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVIGVFAVMHLLGFSINVLTILAIILAIGLV 405
Cdd:NF033617 318 LYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLV 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 406 VDDAIVVAENCYRHIEEGETPFNAAIKGCREIVFPVIAMTLTLAVVYLPIGLMAGLTADLFRQFAFTLAAAVIISGFVAL 485
Cdd:NF033617 398 VDDAIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVAL 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 486 TLSPMMSAYLMKPVSTPAKWYQKVDAKLNVLSDLYTKELGKWFDRKALMSGIALVLIALSALAVWKMPQVLLPTEDTGFV 565
Cdd:NF033617 478 TLTPMMCSRLLKANEKPGRFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 566 EVTSTPPTGVGRQYHLDNNAQLNSVFKGDSSVEANLSYIEGTPTNH-------VLLKPWGERgqsaDELVNEFIAKAQSS 638
Cdd:NF033617 558 FGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGNPGdntgfgiINLKPWDER----DVSAQEIIDRLRPK 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 639 VSAY-GMSFKVRSADNLNIAT---NMILELTTVNRDTTVLSETASEVVKALEDYEGVTNIKNSMLRDQLRYDLSIDRNAI 714
Cdd:NF033617 634 LAKVpGMDLFLFPLQDLPGGAgssLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKA 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 715 VLSGVDYGNVTNALSTFLGSVKAADLQaDDGYTYPIQVQVNRSDLGDFKVLDKLYVDSQSGQRLPLSQFVSIKQVTSESN 794
Cdd:NF033617 714 ARLGISMQDIGSTLEVAFGQRQVNTIY-TDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERAAPLS 792
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 795 FKTFMGKDSAEITADLMPGYMASDVKAYIDDTVPSLLKPAQSYEFNGIVKDLVDSTAGAQVLFVLALIFIFLILAAQFES 874
Cdd:NF033617 793 LNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKELLPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYES 872
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 875 FVDPMIILLTVPLCIVGAILTLSVFGQSLNIYSKIGLLTLVGLVTKHGILLVEFANE-KRKSGASAKEAAISSARSRLRP 953
Cdd:NF033617 873 FVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANElQRHQGLSRREAIYQAAALRLRP 952
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|..
gi 857909416 954 ILMTSLTMILGSLPLALADGPGSLGRINIGLVLVGGLTAGTFFSLFLVPVAY 1005
Cdd:NF033617 953 ILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVY 1004
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
8-1006 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 674.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 8 IKHPVFASVLSITIVLFGLLSFQKLSIQYFPEHKTPSATVTAAINGASAEFMSRNVADKLITAATGLDSVKTMTTDCQEG 87
Cdd:pfam00873 6 IRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSSQSSYG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 88 TCNLKIIFEDDI------NDVE--YTSLMNNLRSSVEaigdfPPSMTdkptVTDDSSDTSMpsnIITFVNT-GKMSKQDM 158
Cdd:pfam00873 86 LSSITLTFELGTdidiarQDVQnrLQLATPLLPEGVQ-----RPGIS----VIKTSLGPIM---VLAVTSPdGSYTQTDL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 159 YDYISQQVVPQFKHIQGVGGIwGPYGGSEKAVRVWLQPDRMMALNMSASDVVGTLSSYNATFTAGTIKGLVRDFSINPVN 238
Cdd:pfam00873 154 RDYADTNIKPQLSRVPGVGDV-QLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQG 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 239 QVTSVDDVRDLVVRVDDGKIIRIGDIAEVKMGEENLTpSILRVDDNLAMSIQVLPLKSENPVTVANKVKKQIDLIQPQLP 318
Cdd:pfam00873 233 QLQSAEDFEKIIVKNQDGSPVRLRDVATVELGSELYR-GFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFP 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 319 EGIEMKMVYNQADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVIGVFAVMHLLGFSINVLTILAI 398
Cdd:pfam00873 312 QGVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGL 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 399 ILAIGLVVDDAIVVAENCYRHIEE-GETPFNAAIKGCREIVFPVIAMTLTLAVVYLPIGLMAGLTADLFRQFAFTLAAAV 477
Cdd:pfam00873 392 VLAIGLVVDDAIVVVENIERVLEEnGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAI 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 478 IISGFVALTLSPMMSAYLMKPVSTP-----AKWYQKVdakLNVLSDLYTKELGKWFDRKALMSGIALVLIALSALAVWKM 552
Cdd:pfam00873 472 LLSVLVALTLTPALCATLLKPRREPkhggfFRWFNRM---FDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRI 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 553 PQVLLPTEDTGFVEVTSTPPTGVGRQYHLDNNAQLNSVFKGDSSVE---ANLSYIEGTPTN-------HVLLKPWGERG- 621
Cdd:pfam00873 549 PTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVEsvfAVTGFAFSGDNNgpnsgdaFISLKPWKERPg 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 622 --QSADELVNEFIAKAQSSVSAYGMSFKVRSADNLNIAT--NMILELTTVNRDTTVLSETASEVVKALEDYEGVTNIKNS 697
Cdd:pfam00873 629 peKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISgfRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSD 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 698 MLRDQLRYDLSIDRNAIVLSGVDYGNVTNALSTFLGSVKAADLQaDDGYTYPIQVQVN---RSDLGDfkvLDKLYVDSQS 774
Cdd:pfam00873 709 GQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFP-EGGRVYDVVVQLPedfRSSPED---IGQLYVRNPY 784
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 775 GQRLPLSQFVSIKQVTSESNFKTFMGKDSAEITADLMPGYMASDVKAYIDDTVPSL-LKPAQSYEFNGIVKDLVDSTAGA 853
Cdd:pfam00873 785 GKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVkLPPGYGYTWTGQFEQEQLAGNSL 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 854 QVLFVLALIFIFLILAAQFESFVDPMIILLTVPLCIVGAILTLSVFGQSLNIYSKIGLLTLVGLVTKHGILLVEFANEKR 933
Cdd:pfam00873 865 PILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELR 944
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 857909416 934 -KSGASAKEAAISSARSRLRPILMTSLTMILGSLPLALADGPGSLGRINIGLVLVGGLTAGTFFSLFLVPVAYV 1006
Cdd:pfam00873 945 eQEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYV 1018
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
1-1009 |
1.59e-179 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 549.82 E-value: 1.59e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 1 MKLPEICIKHPVFASVLSITIVLFGLLSFQKLSIQYFPEHKTPSATVTAAINGASAEFMSRNVADKLITAATGLDSVKTM 80
Cdd:PRK09579 1 MAFTDPFIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 81 TTDCQEGTCNLKIIFEDDIN-DVEYTSLmnnLRSSVEAIGDFPPSMTDkPTVTDDSSDTSMPSNIITFvnTGKMSKQDMY 159
Cdd:PRK09579 81 TSVSRQNFSIISIYARIGADsDRLFTEL---LAKANEVKNQLPQDAED-PVLSKEAADASALMYISFY--SEEMSNPQIT 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 160 DYISQQVVPQFKHIQGVGGIwGPYGGSEKAVRVWLQPDRMMALNMSASDVVGTLSSYNATFTAGTIKGLVRDFSINPVNQ 239
Cdd:PRK09579 155 DYLSRVIQPKLATLPGMAEA-EILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVTSINASTE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 240 VTSVDDVRDLVVRVDDGKIIRIGDIAEVKMGEENLTpSILRVDDNLAMSIQVLPLKSENPVTVANKVKKQIDLIQPQLPE 319
Cdd:PRK09579 234 LKSAEAFAAIPVKTSGDSRVLLGDVARVEMGAENYD-SISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 320 GIEMKMVYNQADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVIGVFAVMHLLGFSINVLTILAII 399
Cdd:PRK09579 313 NLKVSIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 400 LAIGLVVDDAIVVAENCYRHIEEGETPFNAAIKGCREIVFPVIAMTLTLAVVYLPIGLMAGLTADLFRQFAFTLAAAVII 479
Cdd:PRK09579 393 LAIGLVVDDAIVVVENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVII 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 480 SGFVALTLSPMMSAYLMKPVSTPAKWYQKVDAKLNVLSDLYTKELGKWFDRKALMSGIALVLIALSALAVWKMPQVLLPT 559
Cdd:PRK09579 473 SGIVALTLSPMMCALLLRHEENPSGLAHRLDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSELAPE 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 560 EDTGFVEVTSTPPTGVGRQYHLDNNAQLNSVFKG----DSSVEANLSYIEGTPTNHVLLKPWGERGQSADELVNEFIAKA 635
Cdd:PRK09579 553 EDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSfpeyYSSFQINGFNGVQSGIGGFLLKPWNERERTQMELLPLVQAKL 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 636 QSSVSAYGMSFKVRSADNLNIATNMILELTTVNrDTTVLSETASEVVKALEDYEGVTNIKNSMLRDQLRYDLSIDRNAIV 715
Cdd:PRK09579 633 EEIPGLQIFGFNLPSLPGTGEGLPFQFVINTAN-DYESLLQVAQRVKQRAQESGKFAFLDIDLAFDKPEVVVDIDRAKAA 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 716 LSGVDYGNVTNALSTFLGSVKAADLQAdDGYTYPIQVQVNRSDLGDFKVLDKLYVDSQSGQRLPLSQFVSIKQVTSESNF 795
Cdd:PRK09579 712 QMGVSMQDLGGTLATLLGEGEINRFTI-DGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPLSTLITLSDRARPRQL 790
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 796 KTFMGKDSAEITAdlMPGYMASDVKAYIDDTVPSLLKPAQSYEFNGIVKDLVDSTAGAQVLFVLALIFIFLILAAQFESF 875
Cdd:PRK09579 791 NQFQQLNSAIISG--FPIVSMGEAIETVQQIAREEAPEGFAFDYAGASRQYVQEGSALWVTFGLALAIIFLVLAAQFESF 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 876 VDPMIILLTVPLCIVGAILTLSVFGQSLNIYSKIGLLTLVGLVTKHGILLVEFANEKRKS-GASAKEAAISSARSRLRPI 954
Cdd:PRK09579 869 RDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRHEqGLSRREAIEEAAAIRLRPV 948
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*
gi 857909416 955 LMTSLTMILGSLPLALADGPGSLGRINIGLVLVGGLTAGTFFSLFLVPVAYVGMA 1009
Cdd:PRK09579 949 LMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLLA 1003
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
8-1006 |
1.07e-178 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 548.56 E-value: 1.07e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 8 IKHPVFASVLSITIVLFGLLSFQKLSIQYFPEHKTPSATVTAAINGASAEFMSRNVADKLITAATGLDSVKTM-TTDCQE 86
Cdd:TIGR00915 6 IDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMsSSSDSD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 87 GTCNLKIIFEDDIN-DVEYTSLMNNLRssvEAIGDFPPSMTDKP-TVTDDSSDTSMpsnIITFVNT-GKMSKQDMYDYIS 163
Cdd:TIGR00915 86 GSMTITLTFEQGTDpDIAQVQVQNKLQ---LATPLLPQEVQRQGvRVEKASSNFLM---VIGLVSDdGSMTKEDLSDYAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 164 QQVVPQFKHIQGVGGIwgPYGGSEKAVRVWLQPDRMMALNMSASDVVGTLSSYNATFTAGTIKGL--VR----DFSINPV 237
Cdd:TIGR00915 160 SNMVDPLSRLEGVGDV--QLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLpaVPgqqlNATIIAQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 238 NQVTSVDDVRDLVVRVD-DGKIIRIGDIAEVKMGEENLTpSILRVDDNLAMSIQVLPLKSENPVTVANKVKKQIDLIQPQ 316
Cdd:TIGR00915 238 TRLQTPEQFENILLKVNtDGSQVRLKDVARVELGGENYS-ISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPF 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 317 LPEGIEMKMVYNQADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVIGVFAVMHLLGFSINVLTIL 396
Cdd:TIGR00915 317 FPQGMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMF 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 397 AIILAIGLVVDDAIVVAENCYRHI-EEGETPFNAAIKGCREIVFPVIAMTLTLAVVYLPIGLMAGLTADLFRQFAFTLAA 475
Cdd:TIGR00915 397 AMVLAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVS 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 476 AVIISGFVALTLSPMMSAYLMKPVSTPAK---------WYQKVdakLNVLSDLYTKELGKWFDRKALMSGIALVLIALSA 546
Cdd:TIGR00915 477 AMALSVLVALILTPALCATMLKPIEKGEHhekkggffgWFNRM---FDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMV 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 547 LAVWKMPQVLLPTEDTGFVEVTSTPPTGVGRQYHLDNNAQLNSVF--KGDSSVEA----NLSYIEGTPTNH----VLLKP 616
Cdd:TIGR00915 554 FLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLlaKEKANVESvftvNGFSFAGRGQNMgmafIRLKD 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 617 WGERgQSADELVNEFIAKAQssvsayGMSFKVRSADNLNIATNMILELTT-----------VNRDTTVLSETASEVVKAL 685
Cdd:TIGR00915 634 WEER-TGKENSVFAIAGRAT------GHFMQIKDAMVIAFVPPAILELGNatgfdfflqdrAGLGHEALLQARNQLLGLA 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 686 EDYEGVTNIKNSMLRDQLRYDLSIDRNAIVLSGVDYGNVTNALSTFLGSVKAADLqADDGYTYPIQVQVN---RSDLGDf 762
Cdd:TIGR00915 707 AQNPALTRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDF-IDRGRVKRVYVQAEedaRMSPED- 784
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 763 kvLDKLYVDSQSGQRLPLSQFVSIKQVTSESNFKTFMGKDSAEITADLMPGYMASDVKAYIDDTVpSLLKPAQSYEFNGI 842
Cdd:TIGR00915 785 --INKWYVRNASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIA-QKLPPGFGFSWTGM 861
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 843 VKDLVDSTAGAQVLFVLALIFIFLILAAQFESFVDPMIILLTVPLCIVGAILTLSVFGQSLNIYSKIGLLTLVGLVTKHG 922
Cdd:TIGR00915 862 SYEERLSGSQAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNA 941
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 923 ILLVEFANEKRKSGASAKEAAISSARSRLRPILMTSLTMILGSLPLALADGPGSLGRINIGLVLVGGLTAGTFFSLFLVP 1002
Cdd:TIGR00915 942 ILIVEFAKELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVP 1021
|
....
gi 857909416 1003 VAYV 1006
Cdd:TIGR00915 1022 LFYV 1025
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
8-1006 |
7.88e-139 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 443.50 E-value: 7.88e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 8 IKHPVFASVLSITIVLFGLLSFQKLSIQYFPEHKTPSATVTAAINGASAEFMSRNVADKLITAATGLDSVKTMTTDCQE- 86
Cdd:PRK10555 6 IDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSGt 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 87 GTCNLKIIFEDDIN-DVEYTSLMNNLRSsveAIGDFPPSMTDKPTVTDDSSDTsmpsNIIT--FVNT-GKMSKQDMYDYI 162
Cdd:PRK10555 86 GQASVTLSFKAGTDpDEAVQQVQNQLQS---AMRKLPQAVQNQGVTVRKTGDT----NILTiaFVSTdGSMDKQDIADYV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 163 SQQVVPQFKHIQGVGGIwGPYGgSEKAVRVWLQPDRMMALNMSASDVVGTLSSYNATFTAGTIKGL------VRDFSINP 236
Cdd:PRK10555 159 ASNIQDPLSRVNGVGDI-DAYG-SQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTpsvdkqALNATINA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 237 VNQVTSVDDVRDLVVRVD-DGKIIRIGDIAEVKMGEENLTpSILRVDDNLAMSIQVLPLKSENPVTVANKVKKQIDLIQP 315
Cdd:PRK10555 237 QSLLQTPEQFRDITLRVNqDGSEVTLGDVATVELGAEKYD-YLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQ 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 316 QLPEGIEMKMVYNQADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVIGVFAVMHLLGFSINVLTI 395
Cdd:PRK10555 316 YFPHGLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTM 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 396 LAIILAIGLVVDDAIVVAENCYRHI-EEGETPFNAAIKGCREIVFPVIAMTLTLAVVYLPIGLMAGLTADLFRQFAFTLA 474
Cdd:PRK10555 396 FAMVLAIGLLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIV 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 475 AAVIISGFVALTLSPMMSAYLMKPVSTPAK--------WYQKVdakLNVLSDLYTKELGKWFDRKALMSGIALVLIALSA 546
Cdd:PRK10555 476 SAMVLSVLVAMILTPALCATLLKPLKKGEHhgqkgffgWFNRM---FNRNAERYEKGVAKILHRSLRWILIYVLLLGGMV 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 547 LAVWKMPQVLLPTEDTGFVEVTSTPPTGVGRQYHLDNNAQLNSVF--KGDSSVEANLSYIEGTPTNH--------VLLKP 616
Cdd:PRK10555 553 FLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYftHEKDNVMSVFATVGSGPGGNgqnvarmfIRLKD 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 617 WG-------------ERGQSADELVNE--FIAKAQSSVSAYGMS--FKVRSADNLNIATNMILELttvnRDTtvLSETAS 679
Cdd:PRK10555 633 WDerdsktgtsfaiiERATKAFNKIKEarVIASSPPAISGLGSSagFDMELQDHAGAGHDALMAA----RNQ--LLALAA 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 680 EvvkaledYEGVTNIKNSMLRD--QLRYDlsIDRNAIVLSGVDYGNVTNALSTFLGSVKAADLqADDGYTYPIQVQVNrs 757
Cdd:PRK10555 707 K-------NPELTRVRHNGLDDspQLQID--IDQRKAQALGVSIDDINDTLQTAWGSSYVNDF-MDRGRVKKVYVQAA-- 774
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 758 dlGDFKVL----DKLYVDSQSGQRLPLSQFVSIKQVTSESNFKTFMGKDSAEITADLMPGYMASDVKAYIDDTVPSLlkP 833
Cdd:PRK10555 775 --APYRMLpddiNLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQL--P 850
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 834 AQ-SYEFNGIVKDLVDSTAGAQVLFVLALIFIFLILAAQFESFVDPMIILLTVPLCIVGAILTLSVFGQSLNIYSKIGLL 912
Cdd:PRK10555 851 NGfGLEWTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLL 930
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 913 TLVGLVTKHGILLVEFANEKRKSGASAKEAAISSARSRLRPILMTSLTMILGSLPLALADGPGSLGRINIGLVLVGGLTA 992
Cdd:PRK10555 931 TVIGLSAKNAILIVEFANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMIS 1010
|
1050
....*....|....
gi 857909416 993 GTFFSLFLVPVAYV 1006
Cdd:PRK10555 1011 ATILAIFFVPLFFV 1024
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
8-1006 |
2.15e-133 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 428.89 E-value: 2.15e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 8 IKHPVFASVLSITIVLFGLLSFQKLSIQYFPEHKTPSATVTAAINGASAEFMSRNVADKLITAATGLDSVKTMTTDCQEG 87
Cdd:PRK09577 6 IDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSAG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 88 TCNLKIIFEDDIN-DVEYTSLMNNLRSsVEAigDFPPSMTDKPTVTDDSSDTSMPSNIITfVNTGKMSKQDMYDYISQQV 166
Cdd:PRK09577 86 QASLSLTFKQGVNaDLAAVEVQNRLKT-VEA--RLPEPVRRDGIQVEKAADNIQLIVSLT-SDDGRLTGVELGEYASANV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 167 VPQFKHIQGVGGI--WGPyggsEKAVRVWLQPDRMMALNMSASDVVGTLSSYNATFTAGTIKGL-VRDFSinPVNQVTSV 243
Cdd:PRK09577 162 LQALRRVEGVGKVqfWGA----EYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSaVPDSA--PIAATVFA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 244 D-------DVRDLVVRVD-DGKIIRIGDIAEVKMGEENLT-PSilRVDDNLA--MSIQVLPlkSENPVTVANKVKKQIDL 312
Cdd:PRK09577 236 DaplktpeDFGAIALRARaDGSALYLRDVARIEFGGNDYNyPS--YVNGKTAtgMGIKLAP--GSNAVATEKRVRATMDE 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 313 IQPQLPEGIEMKMVYNQADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVIGVFAVMHLLGFSINV 392
Cdd:PRK09577 312 LSRYFPPGVKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINV 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 393 LTILAIILAIGLVVDDAIVVAENCYR-HIEEGETPFNAAIKGCREIVFPVIAMTLTLAVVYLPIGLMAGLTADLFRQFAF 471
Cdd:PRK09577 392 LTMFGMVLAIGILVDDAIVVVENVERlMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFAL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 472 TLAAAVIISGFVALTLSPMMSAYLMKPVSTPAK-------WYQKVDAKlnvLSDLYTKELGKWFDRKALMSGIALVLIAL 544
Cdd:PRK09577 472 SLAVSIGFSAFLALSLTPALCATLLKPVDGDHHekrgffgWFNRFVAR---STQRYATRVGAILKRPLRWLVVYGALTAA 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 545 SALAVWKMPQVLLPTEDTGFVEVTSTPPTGVGRQYHLDNNAQLNSVFKGDSSVEANLS------YIEGTPTN--HVLLKP 616
Cdd:PRK09577 549 AALLFTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFAlggfnlYGEGPNGGmiFVTLKD 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 617 WGERgQSADELVNEFIAKAQSSVsaYG----MSFKVRSADNLNIATNMILELTTVNR---DTTVLSETASEVVKALEDYE 689
Cdd:PRK09577 629 WKER-KAARDHVQAIVARINERF--AGtpntTVFAMNSPALPDLGSTSGFDFRLQDRgglGYAAFVAAREQLLAEGAKDP 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 690 GVTNIKNSMLRDQLRYDLSIDRNAIVLSGVDYGNVTNALSTFLGS-----------VKAADLQADDgytypiqvqVNRSD 758
Cdd:PRK09577 706 ALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSdyigdfmhgsqVRRVIVQADG---------RHRLD 776
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 759 LGDFKvldKLYVDSQSGQRLPLSQFVSIKQVTSESNFKTFMGKDSAEITADLMPGYMASDVKAYIDDTVPSLlkPAQ-SY 837
Cdd:PRK09577 777 PDDVK---KLRVRNAQGEMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAATL--PAGiGY 851
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 838 EFNGIVKDLVDSTAGAQVLFVLALIFIFLILAAQFESFVDPMIILLTVPLCIVGAILTLSVFGQSLNIYSKIGLLTLVGL 917
Cdd:PRK09577 852 AWSGQSFEERLSGAQAPMLFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGL 931
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 918 VTKHGILLVEFANEKRKSGASAKEAAISSARSRLRPILMTSLTMILGSLPLALADGPGSLGRINIGLVLVGGLTAGTFFS 997
Cdd:PRK09577 932 SAKNAILIVEVAKDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLA 1011
|
....*....
gi 857909416 998 LFLVPVAYV 1006
Cdd:PRK09577 1012 VFLVPLFFV 1020
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
2-1005 |
2.05e-128 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 415.58 E-value: 2.05e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 2 KLPEICIKHPVFASVLSITIVLFGLLSFQKLSIQYFPEHKTPSATVTAAINGASAEFMSRNVADKLITAATGLDSVKTMT 81
Cdd:COG3696 4 RIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 82 TDCQEGTCNLKIIFEDDINDveYTSlmnnlRSSV-----EAIGDFPPSMTdkPTVTDDSSDTSmpsNIITFVNTGKMSKQ 156
Cdd:COG3696 84 SISRFGLSVVTVIFEDGTDI--YWA-----RQLVlerlqQVREQLPAGVT--PELGPISTGLG---EIYQYTLESDPGKY 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 157 DMYDYISQQ---VVPQFKHIQGVGGIwGPYGGSEKAVRVWLQPDRMMALNMSASDVVGTLSSYNATFTAGTI-KG----L 228
Cdd:COG3696 152 SLMELRTLQdwvIRPQLRSVPGVAEV-NSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIeRGgqeyL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 229 VRdfsinPVNQVTSVDDVRDLVVRVDDGKIIRIGDIAEVKMGEENLTPSILRVDDNLAMSIQVLPLKSENPVTVANKVKK 308
Cdd:COG3696 231 VR-----GIGLIRSLEDIENIVVKTRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKA 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 309 QIDLIQPQLPEGIEMKMVYNQADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVIGVFAVMHLLGF 388
Cdd:COG3696 306 KLAELKPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGI 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 389 SINVLTILAIILAIGLVVDDAIVVAENCYRHIEE------GETPFNAAIKGCREIVFPVIAMTLTLAVVYLPIGLMAGLT 462
Cdd:COG3696 386 SANLMSLGGLAIDFGIIVDGAVVMVENILRRLEEnraagtPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVE 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 463 ADLFRQFAFTLAAAVIISGFVALTLSPMMSAYLMKPvstpakwyqKVDAKLNVLSD----LYTKELGKWFDRKALMSGIA 538
Cdd:COG3696 466 GKLFRPMALTVIFALLGALLLSLTLVPVLASLLLRG---------KVPEKENPLVRwlkrLYRPLLRWALRHPKLVLAVA 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 539 LVLIALSALAVWKMPQVLLPTEDTGFVEVTSTPPTGVGRQYHLDNNAQLNSVFKGDSSVE---------------ANLSY 603
Cdd:COG3696 537 LVLLVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVEsvvsrtgraedatdpMGVNM 616
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 604 IEgtptNHVLLKPWGE--RGQSADELVNEFiakaQSSVSAY-GMSFkvrsadNLN--IATNmILELTTVNR--------- 669
Cdd:COG3696 617 SE----TFVILKPRSEwrSGRTKEELIAEM----REALEQIpGVNF------NFSqpIQMR-VDELLSGVRadvavkifg 681
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 670 -DTTVLSETASEVVKALEDYEGVTNI---KNSMLRdQLryDLSIDRNAIVLSGVDYGNVTNALSTFLGSVKAADLQaDDG 745
Cdd:COG3696 682 dDLDVLRRLAEQIEAVLKTVPGAADVqveRVTGLP-QL--DIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVY-EGE 757
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 746 YTYPIQVQVNRSDLGDFKVLDKLYVDSQSGQRLPLSQFVSIKQVTSESNFKTFMGKDSAEITADL----MPGYMAsDVKA 821
Cdd:COG3696 758 RRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEVVEGPNQISRENGRRRIVVQANVrgrdLGSFVA-EAQA 836
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 822 YIDDTVPslLKPAQSYEFNGIVKDLVDSTAGAQVLFVLALIFIFLILAAQFESFVDPMIILLTVPLCIVGAILTLSVFGQ 901
Cdd:COG3696 837 KVAEQVK--LPPGYYIEWGGQFENLQRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGM 914
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 902 SLNIYSKIGLLTLVGLVTKHGILLVEFANEKRKSGASAKEAAISSARSRLRPILMTSLTMILGSLPLALADGPGS--LGR 979
Cdd:COG3696 915 PLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSevQRP 994
|
1050 1060
....*....|....*....|....*.
gi 857909416 980 INIglVLVGGLTAGTFFSLFLVPVAY 1005
Cdd:COG3696 995 LAT--VVIGGLITSTLLTLLVLPALY 1018
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
3-1006 |
4.87e-128 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 415.07 E-value: 4.87e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 3 LPEICIKHPVFASVLSITIVLFGLLSFQKLSIQYFPEHKTPSATVTAAINGASAEFMSRNVADKLITAATGLDSVKTMTT 82
Cdd:PRK15127 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 83 DCQE-GTCNLKIIFEDDIN-DVEYTSLMNNLRSSVEAIgdfpPSMTDKPTVTDDSSDTSMPSnIITFVNT-GKMSKQDMY 159
Cdd:PRK15127 81 NSDStGTVQITLTFESGTDaDIAQVQVQNKLQLAMPLL----PQEVQQQGVSVEKSSSSFLM-VVGVINTdGTMTQEDIS 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 160 DYISQQVVPQFKHIQGVGGIwgPYGGSEKAVRVWLQPDRMMALNMSASDVVGTLSSYNATFTAGT------IKGLVRDFS 233
Cdd:PRK15127 156 DYVAANMKDPISRTSGVGDV--QLFGSQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQlggtppVKGQQLNAS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 234 INPVNQVTSVDDVRDLVVRVD-DGKIIRIGDIAEVKMGEENLTpSILRVDDNLAMSIQVLPLKSENPVTVANKVKKQIDL 312
Cdd:PRK15127 234 IIAQTRLTSTEEFGKILLKVNqDGSRVRLRDVAKIELGGENYD-IIAEFNGQPASGLGIKLATGANALDTAAAIRAELAK 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 313 IQPQLPEGIEMKMVYNQADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVIGVFAVMHLLGFSINV 392
Cdd:PRK15127 313 MEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINT 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 393 LTILAIILAIGLVVDDAIVVAENCYR-HIEEGETPFNAAIKGCREIVFPVIAMTLTLAVVYLPIGLMAGLTADLFRQFAF 471
Cdd:PRK15127 393 LTMFGMVLAIGLLVDDAIVVVENVERvMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSI 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 472 TLAAAVIISGFVALTLSPMMSAYLMKPVST----PAK-----WYQKVDAKlnvLSDLYTKELGKWFDRKALMSGIALVLI 542
Cdd:PRK15127 473 TIVSAMALSVLVALILTPALCATMLKPIAKgdhgEGKkgffgWFNRMFEK---STHHYTDSVGNILRSTGRYLVLYLIIV 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 543 ALSALAVWKMPQVLLPTEDTGFVEVTSTPPTGVGRQ-----------YHLDN-NAQLNSVFKGDSSVEANLSyiEGTPTN 610
Cdd:PRK15127 550 VGMAYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQErtqkvlnevtdYYLTKeKNNVESVFAVNGFGFAGRG--QNTGIA 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 611 HVLLKPWGERgQSADELVNEFIAKAQSSVS----AYGMSFKVRSADNLNIATNMILELT-TVNRDTTVLSETASEVV-KA 684
Cdd:PRK15127 628 FVSLKDWADR-PGEENKVEAITMRATRAFSqikdAMVFAFNLPAIVELGTATGFDFELIdQAGLGHEKLTQARNQLLgEA 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 685 LEDYEGVTNIKNSMLRDQLRYDLSIDRNAIVLSGVDYGNVTNALSTFLGSVKAADLqADDGYTYPIQVQVNrsdlGDFKV 764
Cdd:PRK15127 707 AKHPDMLVGVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDF-IDRGRVKKVYVMSE----AKYRM 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 765 L----DKLYVDSQSGQRLPLSQFVSIKQVTSESNFKTFMGKDSAEITADLMPGYMASDVKAYIDDtVPSLLKPAQSYEFN 840
Cdd:PRK15127 782 LpddiGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEE-LASKLPTGVGYDWT 860
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 841 GIVKDLVDSTAGAQVLFVLALIFIFLILAAQFESFVDPMIILLTVPLCIVGAILTLSVFGQSLNIYSKIGLLTLVGLVTK 920
Cdd:PRK15127 861 GMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAK 940
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 921 HGILLVEFANE-KRKSGASAKEAAISSARSRLRPILMTSLTMILGSLPLALADGPGSLGRINIGLVLVGGLTAGTFFSLF 999
Cdd:PRK15127 941 NAILIVEFAKDlMDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIF 1020
|
....*..
gi 857909416 1000 LVPVAYV 1006
Cdd:PRK15127 1021 FVPVFFV 1027
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
1-1013 |
3.20e-127 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 412.20 E-value: 3.20e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 1 MKLPEICIKHPVFASVLSITIVLFGLLSFQKLSIQYFPEHKTPSATVTAAINGASAEFMSRNVADKLITAATGLDSVKTM 80
Cdd:PRK10614 1 MKFFALFIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 81 TTDCQEGTCNLKIIFE--DDINdveytSLMNNLRSSVEAIGDFPPS-MTDKPTVTD-DSSDTsmPSNIITFVNTgKMSKQ 156
Cdd:PRK10614 81 TSSSSLGSTRIILQFDfdRDIN-----GAARDVQAAINAAQSLLPSgMPSRPTYRKaNPSDA--PIMILTLTSD-TYSQG 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 157 DMYDYISQQVVPQFKHIQGVGGIwGPYGGSEKAVRVWLQPDRMMALNMSASDVVGTLSSYNATFTAGTIKGLVRDFSINP 236
Cdd:PRK10614 153 QLYDFASTQLAQTISQIDGVGDV-DVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQT 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 237 VNQVTSVDDVRDLVVRVDDGKIIRIGDIAEVK--------MGEENLTPSILRVddnlamsIQVLPlkSENPVTVANKVKK 308
Cdd:PRK10614 232 NDELKTAAEYQPLIIHYNNGAAVRLGDVATVTdsvqdvrnAGMTNAKPAILLM-------IRKLP--EANIIQTVDRIRA 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 309 QIDLIQPQLPEGIEMKMVYNQADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVIGVFAVMHLLGF 388
Cdd:PRK10614 303 KLPELRETIPAAIDLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGF 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 389 SINVLTILAIILAIGLVVDDAIVVAENCYRHIEEGETPFNAAIKGCREIVFPVIAMTLTLAVVYLPIGLMAGLTADLFRQ 468
Cdd:PRK10614 383 SLNNLSLMALTIATGFVVDDAIVVLENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFRE 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 469 FAFTLAAAVIISGFVALTLSPMMSAYLMKPVSTPAKWYQKVDAK-LNVLSDLYTKELgKWFDRKALMSGiaLVLIALSAL 547
Cdd:PRK10614 463 FAVTLSVAIGISLLVSLTLTPMMCAWLLKSSKPREQKRLRGFGRmLVALQQGYGRSL-KWVLNHTRWVG--VVLLGTIAL 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 548 AVW---KMPQVLLPTEDTG----FVEVTSTpptgVGRQYHLDNNAQLNSVFKGDSSVEANLSYIEGTPTNH----VLLKP 616
Cdd:PRK10614 540 NVWlyiSIPKTFFPEQDTGrlmgFIQADQS----ISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSgmmfITLKP 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 617 WGERGQSADELVNEFIAKAQSSVsayGMSFKVRSADNLNIA---TNMILELTTVNRDTTVLSETASEVVKALEDYEGVTN 693
Cdd:PRK10614 616 LSERSETAQQVIDRLRVKLAKEP---GANLFLMAVQDIRVGgrqSNASYQYTLLSDDLAALREWEPKIRKALAALPELAD 692
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 694 IkNSMLRDQ-LRYDLSIDRNAIVLSGVDYGNVTNALSTFLGSVKAADLQADDGyTYPIQVQVNRSDLGDFKVLDKLYVDS 772
Cdd:PRK10614 693 V-NSDQQDKgAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLN-QYKVVMEVDPRYTQDISALEKMFVIN 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 773 QSGQRLPLSQFVSIKQVTSESNFKTFMGKDSAEITADLMPGYMASDVKAYIDDTVPSLLKPAQSY-EFNGIVKDLVDSTA 851
Cdd:PRK10614 771 NEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIERAMTQLGVPSTVRgSFAGTAQVFQETMN 850
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 852 GAQVLFVLALIFIFLILAAQFESFVDPMIILLTVPLCIVGAILTLSVFGQSLNIYSKIGLLTLVGLVTKHGILLVEFANE 931
Cdd:PRK10614 851 SQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALE 930
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 932 KRKSGA-SAKEAAISSARSRLRPILMTSLTMILGSLPLALADGPGSLGRINIGLVLVGGLTAGTFFSLFLVPVAYVGMAN 1010
Cdd:PRK10614 931 AQRNGNlTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDR 1010
|
...
gi 857909416 1011 LKQ 1013
Cdd:PRK10614 1011 LRL 1013
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
8-1006 |
4.41e-106 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 355.19 E-value: 4.41e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 8 IKHPVFASVLSITIVLFGLLSFQKLSIQYFPEHKTPSATVTAAINGASAEFMSRNVADKLITAATGLDSVKTMTTDCQEG 87
Cdd:PRK10503 17 ILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 88 TCNLKIIFED----DINDVEYTSLMNNLRSSVEAIGDFPPSMT-----DKPTVTDDSSDTSMPsniITFVntgkmskQDM 158
Cdd:PRK10503 97 ASVITLQFQLtlplDVAEQEVQAAINAATNLLPSDLPNPPVYSkvnpaDPPIMTLAVTSTAMP---MTQV-------EDM 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 159 YDYISQQVVPQfkhIQGVGGIwGPYGGSEKAVRVWLQPDRMMALNMSASDVVGTLSSYNATFTAGTIKGLVRDFSINPVN 238
Cdd:PRK10503 167 VETRVAQKISQ---VSGVGLV-TLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSAND 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 239 QVTSVDDVRDLVVRVDDGKIIRIGDIAEVKMGEENL--------TPSILrvddnlaMSIQVLPlkSENPVTVANKVKKQI 310
Cdd:PRK10503 243 QMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSwlgawankQQAIV-------MNVQRQP--GANIIATADSIRQML 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 311 DLIQPQLPEGIEMKMVYNQADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVIGVFAVMHLLGFSI 390
Cdd:PRK10503 314 PQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSI 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 391 NVLTILAIILAIGLVVDDAIVVAENCYRHIEEGETPFNAAIKGCREIVFPVIAMTLTLAVVYLPIGLMAGLTADLFRQFA 470
Cdd:PRK10503 394 NNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFA 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 471 FTLAAAVIISGFVALTLSPMMSAYLMKPVS--TPAKWYQKVDAKLNVLSDLYTKELGKWFDRKALMSGIALVLIALSALA 548
Cdd:PRK10503 474 VTLAVAILISAVVSLTLTPMMCARMLSQESlrKQNRFSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLL 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 549 VWKMPQVLLPTEDTGFVEVTSTPPTGVGRQYHLDNNAQLNSVFKGDSSVEANLSYIEGTPTNHVL--------LKPWGER 620
Cdd:PRK10503 554 WIFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLnsarlqinLKPLDER 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 621 gqsaDELVNEFIAKAQSSVSAY-GMSFKVRSADNLNIATNMILELTTVNRDTTVLSETASEVVKALEDYEGVTNIK--NS 697
Cdd:PRK10503 634 ----DDRVQKVIARLQTAVAKVpGVDLYLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPKLMEKLQQLPQLSdvSS 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 698 MLRDQ-LRYDLSIDRNAIVLSGVDYGNVTNALSTFLGS--VKAADLQADDgytYPIQVQVNRSDLGDFKVLDKLYVDSQS 774
Cdd:PRK10503 710 DWQDKgLVAYVNVDRDSASRLGISMADVDNALYNAFGQrlISTIYTQANQ---YRVVLEHNTENTPGLAALDTIRLTSSD 786
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 775 GQRLPLSQFVSIKQVTSESNFKTFMGKDSAEITADLMPGYMASDVKAYIDDTVPSLLKPAQ-SYEFNGIVKDLVDSTAGA 853
Cdd:PRK10503 787 GGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLNLPADiTTQFQGSTLAFQSALGST 866
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 854 QVLFVLALIFIFLILAAQFESFVDPMIILLTVPLCIVGAILTLSVFGQSLNIYSKIGLLTLVGLVTKHGILLVEFA-NEK 932
Cdd:PRK10503 867 VWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFAlAAE 946
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 857909416 933 RKSGASAKEAAISSARSRLRPILMTSLTMILGSLPLALADGPGSLGRINIGLVLVGGLTAGTFFSLFLVPVAYV 1006
Cdd:PRK10503 947 REQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTTPVIYL 1020
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
16-1005 |
6.04e-90 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 310.92 E-value: 6.04e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 16 VLSITIVL--FGLLSFQKLSIQYFPEHKTPSATVTAAINGASAEFMSRNVADKLITAATGLDSVKTMTTDCQEGTCNLKI 93
Cdd:TIGR00914 16 VLLATLVMaiLGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLSRYGLSQVTV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 94 IFEDDINDVEYTSLMN--------NLRSSVEA--------IGD-FPPSMTDKPTVTDDSSDTSMPSNIITfvntgkmskq 156
Cdd:TIGR00914 96 IFKDGTDLYFARQLVNerlqqardNLPEGVSPemgpistgLGEiFLYTVEAEEGARKKDGGAYTLTDLRT---------- 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 157 dMYDYIsqqVVPQFKHIQGVGGIwGPYGGSEKAVRVWLQPDRMMALNMSASDVVGTLSSYNATFTAGTIKGLVRDFSINP 236
Cdd:TIGR00914 166 -IQDWI---IRPQLRTVPGVAEV-NSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 237 VNQVTSVDDVRDLVVRVDDGKIIRIGDIAEVKMGEENLTPSILRVDDNLAMSIqVLPLKSENPVTVANKVKKQIDLIQPQ 316
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIATGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGT-VFMLIGENSRTVAQAVGDKLETINKT 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 317 LPEGIEMKMVYNQADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVIGVFAVMHLLGFSINVLTIL 396
Cdd:TIGR00914 320 LPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLG 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 397 AiiLAIGLVVDDAIVVAENCYRHIEEG----------ETPFNAAIKGCREIVFPVIAMTLTLAVVYLPIGLMAGLTADLF 466
Cdd:TIGR00914 400 A--LDFGLIVDGAVVIVENAHRRLAEAqhhhgrqltlKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMF 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 467 RQFAFTLAAAVIISGFVALTLSPMMSAYLMKpvstpakwyQKVDAKLN----VLSDLYTKELGKWFDRKALMSGIALVLI 542
Cdd:TIGR00914 478 HPMAFTVVLALAGAMILSLTFVPAAVALFIR---------GKVAEKENrlmrVLKRRYEPLLERVLAWPAVVLGAAAVSI 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 543 ALSALAVWKMPQVLLPTEDTG-----FVEVTSTPPT-GVGRQYHLDNN----AQLNSVFK--GDSSVEANLSYIEGTPTn 610
Cdd:TIGR00914 549 VLVVWIASRVGGEFIPSLNEGdlayqALRIPGTSLAqSVAMQQTLEKLiksfPEVARVFAktGTAEIATDPMPPNASDT- 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 611 HVLLKP---WGERGQSADELVNEFIAKAQSSV-SAYGMSFKVRsadnlniatNMILELTTVNR----------DTTVLSE 676
Cdd:TIGR00914 628 YIILKPesqWPEGKKTKEDLIEEIQEATVRIPgNNYEFTQPIQ---------MRFNELISGVRsdvavkvfgdDLDDLDA 698
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 677 TASEVVKALEDYEGVTNIKNSMLRDQLRYDLSIDRNAIVLSGVDYGNVTNALSTFLGSVKAADLQADDGyTYPIQVQVNR 756
Cdd:TIGR00914 699 TAEKISAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDR-RFDIVIRLPE 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 757 SDLGDFKVLDKLYV-----DSQSGQRLPLSQFVSIKQVTSESNFKTFMGKDSAEITADLMPGYMAS---DVKAYIDDTVP 828
Cdd:TIGR00914 778 SLRESPQALRQLPIplplsEDARKQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSfvdDAKKAIAEQVK 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 829 slLKPAQSYEFNGIVKDLVDSTAGAQVLFVLALIFIFLILAAQFESFVDPMIILLTVPLCIVGAILTLSVFGQSLNIYSK 908
Cdd:TIGR00914 858 --LPPGYWITWGGQFEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAA 935
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 909 IGLLTLVGLVTKHGILLVEFANEKRKSGASAKEAAISSARSRLRPILMTSLTMILGSLPLALADGPGSLGRINIGLVLVG 988
Cdd:TIGR00914 936 VGFIALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIG 1015
|
1050
....*....|....*..
gi 857909416 989 GLTAGTFFSLFLVPVAY 1005
Cdd:TIGR00914 1016 GIITATLLTLFVLPALY 1032
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
237-1002 |
1.79e-29 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 126.13 E-value: 1.79e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 237 VNQVTSVDDVRDLVV---------RVDDGKIIRIGDIAEVK--MGEENLTPSILRVDDNLAMSIQV-LPLKSENPVTVAN 304
Cdd:COG1033 101 VDSVTSLTNVRATEGtedgltvepLIPDELPASPEELAELRekVLSSPLYVGRLVSPDGKATLIVVtLDPDPLSSDLDRK 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 305 KVKKQI-DLIQPQLPEGIEMK---MVYNQADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVIGVF 380
Cdd:COG1033 181 EVVAEIrAIIAKYEDPGVEVYltgFPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTL 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 381 AVMHLLGFSINVLTILAIILAIGLVVDDAIVVAENCYRHIEEGETPFNAAIKGCREIVFPVIAMTLTLAvvylpIGLMAG 460
Cdd:COG1033 261 GLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALREALRKLGPPVLLTSLTTA-----IGFLSL 335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 461 LTADL--FRQFAFTLAAAVIISGFVALTLSPMMSAYLMKPvstpaKWYQKVDAKLNVLSDLYTKeLGKWFDRKALMsgIA 538
Cdd:COG1033 336 LFSDIppIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRP-----KPKTRRLKKPPELGRLLAK-LARFVLRRPKV--IL 407
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 539 LVLIALSALAVWKMPQVllpteDTGFVEVTSTPPTgvgRQYHLDNNAqLNSVFKGDSSVEanlsyiegtptnhVLLKPWG 618
Cdd:COG1033 408 VVALVLAVVSLYGISRL-----KVEYDFEDYLPED---SPIRQDLDF-IEENFGGSDPLE-------------VVVDTGE 465
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 619 ERGqsadelvnefiakaqssvsaygmsfkVRSADNLniatnmilelttvnrdttvlsETASEVVKALEDYEGVTNiknsm 698
Cdd:COG1033 466 PDG--------------------------LKDPEVL---------------------KEIDRLQDYLESLPEVGK----- 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 699 lrdqlrydlsidrnaivlsgvdygnvTNALSTFLGSVKAADLQAD-DGYTYPiqvqvnrsdlGDFKVLDKLYVDSQSGQR 777
Cdd:COG1033 494 --------------------------VLSLADLVKELNQALNEGDpKYYALP----------ESRELLAQLLLLLSSPPG 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 778 LPLSQFVSIKQvtSESNFKTFMGKDSAEITADLMpgymaSDVKAYIDDTVPSllkPAQSYEFNG---IVKDLVDSTAGAQ 854
Cdd:COG1033 538 DDLSRFVDEDY--SAARVTVRLKDLDSEEIKALV-----EEVRAFLAENFPP---DGVEVTLTGsavLFAAINESVIESQ 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 855 VL-FVLALIFIFLILAAQFESFVDPMIILL--TVPLCIVGAILTLsvFGQSLNIYSkIGLLTL-VGLVTKHGILLVEFAN 930
Cdd:COG1033 608 IRsLLLALLLIFLLLLLAFRSLRLGLISLIpnLLPILLTFGLMGL--LGIPLNIAT-AVVASIaLGIGVDYTIHFLSRYR 684
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 857909416 931 EKRKSGASAKEAAISSARSRLRPILMTSLTMILGSLPLALADGPGSlgrINIGLVLVGGLTAGTFFSLFLVP 1002
Cdd:COG1033 685 EERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLFSSFPPL---ADFGLLLALGLLVALLAALLLLP 753
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
233-498 |
7.94e-20 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 95.31 E-value: 7.94e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 233 SINPVNQVTSVDDVRDLVVRV---DDGKIIRIGD----IAEVKMGEENLTPSILR--VDDN---LAMSIQVLPLKSENPV 300
Cdd:COG1033 487 SLPEVGKVLSLADLVKELNQAlneGDPKYYALPEsrelLAQLLLLLSSPPGDDLSrfVDEDysaARVTVRLKDLDSEEIK 566
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 301 TVANKVKKQIDLIQPqlPEGIEMK---MVYNQADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVI 377
Cdd:COG1033 567 ALVEEVRAFLAENFP--PDGVEVTltgSAVLFAAINESVIESQIRSLLLALLLIFLLLLLAFRSLRLGLISLIPNLLPIL 644
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 378 GVFAVMHLLGFSINVLTILAIILAIGLVVDDAIVVAENCYRHIEEGETPFNAAIKGCREIVFPVIAMTLTLAvvylpIGL 457
Cdd:COG1033 645 LTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLA-----AGF 719
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 857909416 458 MAGLTADL--FRQFAFTLAAAVIISGFVALTLSPMMsAYLMKP 498
Cdd:COG1033 720 GVLLFSSFppLADFGLLLALGLLVALLAALLLLPAL-LLLLDP 761
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
802-1008 |
4.34e-12 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 70.27 E-value: 4.34e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 802 DSAEITADLMPGYMASDVKAYIDDTVPSLLK------PAQSYEF-NGIVKDLVdstagaqVLFVLALIFIFLILAAQFES 874
Cdd:COG1033 169 DPDPLSSDLDRKEVVAEIRAIIAKYEDPGVEvyltgfPVLRGDIaEAIQSDLA-------IFFPLALLLILLLLFLFFRS 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 875 FVDPMIILLTVPLCIVGAILTLSVFGQSLNIYSKIGLLTLVGLVTKHGILLVEFANEKRKSGASAKEAAISSARSRLRPI 954
Cdd:COG1033 242 LRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALREALRKLGPPV 321
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 857909416 955 LMTSLTMILGSLPLALADGPgsLGRiNIGLVLVGGLTAGTFFSLFLVPVAYVGM 1008
Cdd:COG1033 322 LLTSLTTAIGFLSLLFSDIP--PIR-DFGIVAAIGVLLAFLTSLTLLPALLSLL 372
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
301-489 |
1.67e-08 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 58.62 E-value: 1.67e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 301 TVANKVKKQI-DLIQPQLPEGIEMKM---VYNQADFIKTAidEGFMTLVEAIVLVSAVVVLFL--GSFRVASIPIITIPV 374
Cdd:COG2409 128 DEAAEAVDALrDAVAAAPAPGLTVYVtgpAALAADLNEAF--EEDLGRAELITLPVALVVLLLvfRSLVAALLPLLTAGL 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 375 CVIGVFAVMHLLGFSINV---LTILAIILAIGLVVDDAI-VVAencyRHIEE---GETPFNAAIKGCREIVFPVIAMTLT 447
Cdd:COG2409 206 AVGVALGLLALLAAFTDVssfAPNLLTMLGLGVGIDYALfLVS----RYREElraGEDREEAVARAVATAGRAVLFSGLT 281
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 857909416 448 LAvvylpIGLMAGLTADL--FRQFAFTLAAAVIISGFVALTLSP 489
Cdd:COG2409 282 VA-----IALLGLLLAGLpfLRSMGPAAAIGVAVAVLAALTLLP 320
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
336-497 |
8.77e-08 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 55.89 E-value: 8.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 336 AIDEGFMTLVEAIVLVSAVVVLFLGSFRVASiPIITIpVCVIGVFAVMHLLGFsinVLT---ILAIILAIGLVVDDAIVV 412
Cdd:COG0342 269 SIEKGLIAGLIGLLLVALFMLLYYRLPGLVA-NIALA-LNVVLLLGVLSLLGA---TLTlpgIAGIILTIGMAVDANVLI 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 413 AEncyRHIEE---GETPFNAAIKGCREiVFPVI----AMTLTLAVV--YLPIGLMAGltadlfrqFAFTLAAAVIISGFV 483
Cdd:COG0342 344 FE---RIREElraGRSLRAAIEAGFKR-AFSTIldanVTTLIAAVVlfVLGTGPVKG--------FAVTLILGILISMFT 411
|
170
....*....|....
gi 857909416 484 ALTLSPMMSAYLMK 497
Cdd:COG0342 412 AVPVTRPLLNLLLG 425
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
336-494 |
5.97e-07 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 53.57 E-value: 5.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 336 AIDEGFMTLVEAIVLVSAVVVLFLGSFRVasIPIITIPVCVIGVFAVMHLLGFSINVLTILAIILAIGLVVDDAIVVAEN 415
Cdd:PRK14726 370 SIAAGLVAGLIAAILVAALMIGFYGFLGV--IAVIALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIGMAVDSNVLIYER 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 416 CYRHIEEGETPFNAAIKGCREIVFPVIAMTLTL---AVVYLPIGLMAgltadlFRQFAFTLAAAVIISGFVALTLSPMMS 492
Cdd:PRK14726 448 IREEEKTGHSLIQALDRGFSRALATIVDANVTIliaAVILFFLGSGA------VRGFAVTLAVGILTTVFTAFTLTRSLV 521
|
..
gi 857909416 493 AY 494
Cdd:PRK14726 522 AV 523
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
197-495 |
5.97e-07 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 53.87 E-value: 5.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 197 DRMMALNMSASDVVGTLSSYNATFTAGTIKGLVRDFSINP---VNQVTSVDDVRDLVVRVDDGKIIRIGDIAEVkmgEEN 273
Cdd:NF033617 711 DKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLevdRRYRLNPEALNQIYVRSNDGKLVPLSTLAKI---EER 787
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 274 LTP-SILRVDDNLAMSIQVLPLKSenpVTVANKVKKQIDLIQPQLPEGIemkmvynQADFIKTAID--EGFMTLVEAIVL 350
Cdd:NF033617 788 AAPlSLNHFNQFNSATLSFNLAPG---VSLGEAIEALDQAAKELLPSGI-------SGSFQGAARAfqEEGSSLLFLFLL 857
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 351 VSAVVVLFLG----SFRVASIPIITIPVCVIGVFAVMHLLGFSINVLTILAIILAIGLVVDDAIVVAE--NCYRHiEEGE 424
Cdd:NF033617 858 ALAAIYLVLAiqyeSFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEfaNELQR-HQGL 936
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 857909416 425 TPFNAAIKGCReIVFPVIAMTlTLAVVY--LPIGLMAGLTADLFRQFAFTLAAAVIISGFVALTLSPMMSAYL 495
Cdd:NF033617 937 SRREAIYQAAA-LRLRPILMT-TLAMLLgaIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLL 1007
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
334-488 |
6.90e-07 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 52.67 E-value: 6.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 334 KTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVasIPIITIPVCVIGVFAVMHLLGFSINVLTILAIILAIGLVVDDAIVVA 413
Cdd:TIGR01129 244 ADSIEAGIKAGLIGLVLVLVFMILYYRLFGL--IAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIY 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 414 ENCYRHIEEGETP---FNAAIKGCREIVFPVIAMTLTLAVV--YLPIGLMAGltadlfrqFAFTLAAAVIISGFVALTLS 488
Cdd:TIGR01129 322 ERIKEELRLGKSVrqaIEAGFERAFSTIFDANITTLIAALIlyVFGTGPVKG--------FAVTLAIGIIASLFTALVFT 393
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
342-495 |
9.71e-07 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 51.91 E-value: 9.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 342 MTLVEAIVLVSAVVVLFL--GSFRVASIPIITIPVCVIGVFAVM----HLLGFSINVLTI-LAIILAIGLVVDDAIVVAE 414
Cdd:pfam03176 144 LGLIEAVTLVVIFIILLIvyRSVVAALLPLLTVGLSLGAAQGLVailaHILGIGLSTFALnLLVVLLIAVGTDYALFLVS 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 415 ncyRHIEE---GETPFNAAIKGCREIVFPVIAMTLTLAvvylpIGLMAGLTADL--FRQFAFTLAAAVIISGFVALTLSP 489
Cdd:pfam03176 224 ---RYREElraGEDREEAVIRAVRGTGKVVTAAGLTVA-----IAMLALSFARLpvFAQVGPTIAIGVLVDVLAALTLLP 295
|
....*.
gi 857909416 490 MMSAYL 495
Cdd:pfam03176 296 ALLALL 301
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
833-1003 |
2.86e-06 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 51.38 E-value: 2.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 833 PAQSYEF-NGIVKDLVDSTAGAQVLFVLALIFIFLILAAQFEsfvdPMIILLTVPLCIVGAILTLsvfGQSLNIYSKIGL 911
Cdd:TIGR00921 181 PAINYDIeREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLL----PLVIILFGVAWVLGIMGWL---GIPLYATTLLAV 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 912 LTLVGLVTKHGILLVEFANEKRKSGASAKEAAISSARSRLRPILMTSLTMILGSLPLALADGPgSLGRINIGLVLvgGLT 991
Cdd:TIGR00921 254 PMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFP-MVSEFGLGLVA--GLI 330
|
170
....*....|..
gi 857909416 992 AGTFFSLFLVPV 1003
Cdd:TIGR00921 331 TAYLLTLLVLPA 342
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
841-1002 |
1.13e-05 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 48.83 E-value: 1.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 841 GIVKDLVDSTA-GAQVLFVLALIFIFLILAAQFESFVDPMIILLTVPLCIVGAILTLSVFGQSLNI---YSKIGLLT--L 914
Cdd:pfam03176 131 ATVADLRDAGDrDLGLIEAVTLVVIFIILLIVYRSVVAALLPLLTVGLSLGAAQGLVAILAHILGIglsTFALNLLVvlL 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 915 VGLVTKHGILLVEFANEKRKSGASAKEAAISSARSRLRPILMTSLTMILGSLPLALADGPgSLGRinIGLVLVGGLTAGT 994
Cdd:pfam03176 211 IAVGTDYALFLVSRYREELRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFARLP-VFAQ--VGPTIAIGVLVDV 287
|
....*...
gi 857909416 995 FFSLFLVP 1002
Cdd:pfam03176 288 LAALTLLP 295
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
300-489 |
2.27e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 48.29 E-value: 2.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 300 VTVANKVKKQIDLIQPqlPEGIEMKMVYNQAdfIKTAIDEGF---MTLVEAIVLVSAVVVLFLgSFRVASIPIITIPVCV 376
Cdd:TIGR00921 154 VPIYNDVERSLERTNP--PSGKFLDVTGSPA--INYDIEREFgkdMGTTMAISGILVVLVLLL-DFKRWWRPLLPLVIIL 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 377 IGV---FAVMHLLGFSINVLTILAIILAIGLVVDDAIVVAENCYRHIEEGETPFNAAIKGCREiVFPVIAMTLTLAVvyl 453
Cdd:TIGR00921 229 FGVawvLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRR-TGRAVLIALLTTS--- 304
|
170 180 190
....*....|....*....|....*....|....*...
gi 857909416 454 pIGLMAGLTADL--FRQFAFTLAAAVIISGFVALTLSP 489
Cdd:TIGR00921 305 -AGFAALALSEFpmVSEFGLGLVAGLITAYLLTLLVLP 341
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
334-485 |
2.83e-05 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 46.10 E-value: 2.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 334 KTAIDEGFMTLVEAIVLVSAVVVL-FLGSFRVASIPIITIPVCVIgvFAVMHLLGFSINVLTILAIILAIGLVVDDAIVV 412
Cdd:TIGR00916 43 GELIKAGIIALLIGLVLVLLYMLLrYEWRGAIAAIAALVHDVILI--LGVLSLFGATLTLPGIAGLLTIIGYSVDDTVVI 120
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 857909416 413 AENCY--RHIEEGETPFNAAIKGCREIVFPVIAMTLT--LAVVYLPIglmagLTADLFRQFAFTLAAAVIISGFVAL 485
Cdd:TIGR00916 121 FDRIReeLRKYKGRTFREAINLGINQTLSRIIDTNVTtlLAVLALYV-----FGGGAIKGFALTLGIGVIAGTYSSI 192
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
297-504 |
3.87e-05 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 47.69 E-value: 3.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 297 ENPVTVANKVKKQIDLIQPQLPEGIEMKMVYNQADFIKTAIDEGFMTLVE--------------AIVLVSAVVVLFLGSF 362
Cdd:PRK13023 215 DNQVVSAPTVSGPLDTSELQIEGAFDLQAANNMAVVLRSGALPQAVTVLEertiasalgedyasAAVLAALLAALVVGLF 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 363 RVAS------IPIITIPVCVIGVFAVMHLLGFSINVLTILAIILAIGLVVDDAIVVAENCYRHIEEGETPFNAAIKGCRE 436
Cdd:PRK13023 295 MVLSygilgvIALVALVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDRRKGYSVVQAMESGFYR 374
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 857909416 437 IVFPVIAMTLTLAVVYLPIGLMAGLTAdlfRQFAFTLAAAVIISGFVALTLSPMMSAYLM---KPVSTPAK 504
Cdd:PRK13023 375 ALSTIVDANLTTLIAALVLFLLGSGTV---HGFALTVAIGIGTTLFTTLTFTRLLIAQWVrtaKPKEVPKR 442
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
856-1002 |
8.68e-05 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 46.77 E-value: 8.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 856 LFVLALIFIFLILAAQFESFVDPMIILLTVPLCIVGAILTLSVFGQSLNIYSKIGLLTLVGLVTKHGIllveFANEKRKS 935
Cdd:COG4258 644 LLLLALLLILLLLLLRLRSLRRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYAL----FFTEGLLD 719
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 857909416 936 GAsakeaaisSARSRLRPILMTSLTMILGSLPLALADGPGslgrIN-IGLVLVGGLTAGTFFSLFLVP 1002
Cdd:COG4258 720 KG--------ELARTLLSILLAALTTLLGFGLLAFSSTPA----LRsFGLTVLLGILLALLLAPLLAP 775
|
|
| Patched |
pfam02460 |
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ... |
330-489 |
1.54e-04 |
|
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.
Pssm-ID: 308203 [Multi-domain] Cd Length: 793 Bit Score: 45.81 E-value: 1.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 330 ADFIKTAIDEGFMTLVEAIVLVSAVVVLFLGSFRVASIPIITIPVCVIGVFAVMHLLGFSINVLTILAIILAIGLVVDDA 409
Cdd:pfam02460 631 ADQYLTILPSTIQNIVITLICMFIVCFLFIPNPPCVFVITLAIASIDIGVFGFLSLWGVDLDPISMITIIMSIGFSVDFS 710
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 410 IVVAENCYRhiEEGETPFNAAIKGCREIVFPVI--AMTLTLAVVylpigLMAGLTADLFRQFAFTLAAAVIISGFVALTL 487
Cdd:pfam02460 711 AHIAYHFVR--SRGDTPAERVVDALEALGWPVFqgGLSTILGVL-----VLLFVPSYMVVVFFKTVFLVVAIGLLHGLFI 783
|
..
gi 857909416 488 SP 489
Cdd:pfam02460 784 LP 785
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
336-549 |
1.55e-04 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 45.61 E-value: 1.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 336 AIDEGFMTLVEAIVLVSAVVVLFLGSF-RVASIPIITIPVCVIGVFAVMHllgfsiNVLT---ILAIILAIGLVVDDAIV 411
Cdd:PRK13024 264 AIDAGIIAGIIGFALIFLFMLVYYGLPgLIANIALLLYIFLTLGALSSLG------AVLTlpgIAGLVLGIGMAVDANVL 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 412 VAENCYRHIEEGETPFNAAIKGCREIVFPVIAMTLTLavvylpiGLMAGLtadLF-------RQFAFTLAAAVIISGFVA 484
Cdd:PRK13024 338 IFERIKEELRKGKSLKKAFKKGFKNAFSTILDSNITT-------LIAAAI---LFffgtgpvKGFATTLIIGILASLFTA 407
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 485 LTLSPMMSAYLMKpvSTPAKWYQKVDAKLNVLSDLYTKELGKWFD-----RKALMSGIALVLIALSALAV 549
Cdd:PRK13024 408 VFLTRLLLELLVK--RGDKKPFLFGVKKKKIHNINEGVTIFDRIDfvkkrKWFLIFSIVLVIAGIIIFFI 475
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
841-1002 |
1.80e-04 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 45.53 E-value: 1.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 841 GIVKDLVDSTAGAQVLF-VLALIFIFLILAAQFESFVDPMIILLTVPLCIVGAILTLSVFGQ--SLNIYSkIGLLTLVGL 917
Cdd:COG2409 158 ALAADLNEAFEEDLGRAeLITLPVALVVLLLVFRSLVAALLPLLTAGLAVGVALGLLALLAAftDVSSFA-PNLLTMLGL 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 918 --VTKHGILLVEFANEKRKSGASAKEAAISSARSRLRPILMTSLTMILGSLPLALADGPgSLGriNIGLVLVGGLTAGTF 995
Cdd:COG2409 237 gvGIDYALFLVSRYREELRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGLLLAGLP-FLR--SMGPAAAIGVAVAVL 313
|
....*..
gi 857909416 996 FSLFLVP 1002
Cdd:COG2409 314 AALTLLP 320
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
347-425 |
1.72e-03 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 42.53 E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 347 AIVLVSAVVVLFLGSFRVASIPIITIPVC--VIGVFAVMHLLGFSINVLTILAIILAIGLVVDDAIVVAENCYRHIEEGE 424
Cdd:COG4258 646 LLALLLILLLLLLRLRSLRRALRVLLPPLlaVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYALFFTEGLLDKGELAR 725
|
.
gi 857909416 425 T 425
Cdd:COG4258 726 T 726
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
777-999 |
2.02e-03 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 41.10 E-value: 2.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 777 RLPLSQFVSIKQVTS--------ESNFKTFMGKDSAEITADLMPGYMASDVKayidDTVPSLLKPAQsYEFNGIVKDLVD 848
Cdd:TIGR00966 15 ETRLEQAADVAEVRDvlekagieGVVIQEFGSSHTIMIRIPTLDTEQSEELR----EALEEALKNVD-PDAEIRSIDAVG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 849 STAGAQV------LFVLALIFIFLILAAQFE-SFVDPMIILLTVPLCIVGAILtlSVFGQSLNIYSKIGLLTLVGLVTKH 921
Cdd:TIGR00966 90 PSVGGELarkavlALLAALVLILIYITVRFEwRFALGAIVALVHDVIITVGVY--SLFGIEVNLTTVAALLTIIGYSIND 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 922 GILLVEFANE--KRKSGASAKEAAISSARSRLRPILMTSLTMILGSLPLALADGPGSlgrINIGLVLVGGLTAGTFFSLF 999
Cdd:TIGR00966 168 TVVVFDRIREnlRKYTRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVI---KDFSLALLVGVIVGTYSSIF 244
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
854-987 |
2.04e-03 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 42.29 E-value: 2.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 854 QVLFVLALIFIFLILAAQFESFVDPMIILltVPLcIVGAILTLSV---FGQSLNIYSKIGLLTLVGLVTKHGILLVEFAN 930
Cdd:TIGR03480 715 LQAFIYALVAITVLLLLTLRRVRDVLLVL--APL-LLAGLLTVAAmvlLGIPFNFANIIALPLLLGLGVDFGIYMVHRWR 791
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 931 EKRKSGasakeAAISSarSRLRPILMTSLTMILGSLPLALADGPG--SLGRI-NIGLVLV 987
Cdd:TIGR03480 792 NGVDSG-----NLLQS--STARAVFFSALTTATAFGSLAVSSHPGtaSMGILlSLGLGLT 844
|
|
| secD |
PRK08343 |
preprotein translocase subunit SecD; Reviewed |
330-484 |
6.64e-03 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 236245 [Multi-domain] Cd Length: 417 Bit Score: 40.24 E-value: 6.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 330 ADFIKTAIDEGFMtlveAIVLVSAVVvlflgSFRVASiPIITIPVCVIGVFAVMHLLGFS------INVLTILAIILAIG 403
Cdd:PRK08343 257 EQFKKGSLIAGLL----ALLAVALVV-----FLRYRE-PRIALPMVITSLSEVIIILGFAaligwqLDLASIAGIIAVIG 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 404 LVVDDAIVVA-ENCYRHIEEGETPFNAAIKGCREIVFP-----VIAMtLTLAVvyLPIGLMAGltadlfrqFAFTLAAAV 477
Cdd:PRK08343 327 TGVDDLIIITdEVLHEGKVPSRKVFLSRIKRAFFIIFAaaattIAAM-SPLAV--MGLGDLKG--------FAITTILGV 395
|
....*..
gi 857909416 478 IISGFVA 484
Cdd:PRK08343 396 LIGVLIT 402
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
348-510 |
8.04e-03 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 40.15 E-value: 8.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 348 IVLVSAVVVLFLGSFRVASI-PIITIPVCVIGVFAVMHLLGFSINVLTILAIILAIGLVVDDAIVVAENCYRHIEEG--- 423
Cdd:NF037998 452 LILAIAIMIYLLFAYRLLGLfAIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLYKNkrs 531
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 857909416 424 -ETPFNAAIKGCREIVFPVIAMTLTLAVVYLPIGLMAgltadlFRQFAFTLAAAVIISGFVALTLSPMMSAYLMKpvstp 502
Cdd:NF037998 532 iEESFKIANKETIGIIVDALVVLLIPNLSLFWIGSNS------IKSFATILLVGVIISLVLVIIVARLMIWLTIK----- 600
|
....*...
gi 857909416 503 AKWYQKVD 510
Cdd:NF037998 601 LQWFKKYP 608
|
|
| |
