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Malate synthase G GlcB [Mycobacterium tuberculosis]
Protein Classification
malate synthase G ( domain architecture ID 10011891 )
malate synthase G catalyzes the formation of malate from glyoxylate and acetyl-CoA
List of domain hits
Name
Accession
Description
Interval
E-value
PRK02999
PRK02999 malate synthase G; Provisional
1-726
0e+00
malate synthase G; Provisional
Pssm-ID: 235097 [Multi-domain]
Cd Length: 726
Bit Score: 1544.74
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 1 MT D RV S VG N L RI A R VLYDFVNNEALPGT DI D P D S FWAG VDKV V A DL T P Q N Q ALL NA RDELQA Q ID K WHR RRVIE P I D MD A 80
Cdd:PRK02999 1 MT E RV Q VG G L QV A A VLYDFVNNEALPGT GV D A D A FWAG FAAI V H DL A P K N R ALL AK RDELQA K ID A WHR AHPGP P H D LA A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 81 Y RQ FLTEIGYL L PEP D DFTITT SG VD A EI T T T AGPQLVVPV L NAR F ALNAANARWGSLYDALYGTD V IPE TD GAEKG PT Y 160
Cdd:PRK02999 81 Y KA FLTEIGYL V PEP E DFTITT EN VD P EI A T Q AGPQLVVPV M NAR Y ALNAANARWGSLYDALYGTD A IPE EG GAEKG KG Y 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 161 N K VRG D KVIAYAR K FLD DSV PL S SGS FG D A TG FT V Q DGQLVV A L P D - KS TGLA N P G QF A GY T G A A ES P TSV LL I N H GLHI 239
Cdd:PRK02999 161 N P VRG A KVIAYAR A FLD EAA PL A SGS HA D V TG YA V E DGQLVV T L K D g SE TGLA D P A QF V GY Q G D A AA P SAI LL K N N GLHI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 240 EI L ID PESQV G T TD R AGVKDV I LESA I TTIMD F EDSVAAVDA A DKVL G YRNWLGL N KGDL AAAVD K D G TA F L R V LN R DR N 319
Cdd:PRK02999 241 EI Q ID RNHPI G K TD P AGVKDV V LESA L TTIMD C EDSVAAVDA E DKVL V YRNWLGL M KGDL TEEFE K G G KT F T R R LN P DR E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 320 YTAP G GG QF TL P GRSL M FVRNVGHLMTN D AI V D T DG S E VF EGI M DA LF T G LIA I H G LK A sdv NG PLI NSRTGS I YIVKPK 399
Cdd:PRK02999 321 YTAP D GG EL TL H GRSL L FVRNVGHLMTN P AI L D A DG N E IP EGI L DA VV T S LIA L H D LK G --- NG RRR NSRTGS V YIVKPK 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 400 MHGP A EVAF TC ELF S RVED V LGLP Q NT M K I GIMDEERRT T VNLKACI K AA A DRVVFINTGFLDRTGDEIHTSMEAGPMVR 479
Cdd:PRK02999 398 MHGP E EVAF AN ELF G RVED L LGLP R NT L K V GIMDEERRT S VNLKACI R AA K DRVVFINTGFLDRTGDEIHTSMEAGPMVR 477
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 480 KG T MKS Q PWI L AYED H NVD A GLA A G FS GRAQ V GKGMW T M TE LMADM V E T KIA Q P R AGA S TAWVPSPTAATLHALHYHQVD 559
Cdd:PRK02999 478 KG D MKS S PWI A AYED N NVD I GLA C G LR GRAQ I GKGMW A M PD LMADM L E Q KIA H P K AGA N TAWVPSPTAATLHALHYHQVD 557
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 560 V A AVQ QG LA GK R - RA TIEQ LLTIPLA KELA W APD EI RE E V DNN C Q S ILGYVVRWVDQGVGCSKVPDIHDV A LMEDRATLR 638
Cdd:PRK02999 558 V F AVQ AE LA KT R p RA SLDD LLTIPLA ENAN W SAE EI QQ E L DNN A Q G ILGYVVRWVDQGVGCSKVPDIHDV G LMEDRATLR 637
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 639 ISSQ LL ANWLRHGV I T SAD V RA SL E RMA PL VD R QNAGD V AYRPMAP N FD D SIAF L AA QE L ILS G AQH PNGYTEP I LH R RR 718
Cdd:PRK02999 638 ISSQ HI ANWLRHGV V T EEQ V ME SL K RMA AV VD Q QNAGD P AYRPMAP D FD N SIAF Q AA CD L VFK G REQ PNGYTEP L LH A RR 717
....*...
gi 801449671 719 R E F KA RA A 726
Cdd:PRK02999 718 L E A KA KQ A 725
Name
Accession
Description
Interval
E-value
PRK02999
PRK02999 malate synthase G; Provisional
1-726
0e+00
malate synthase G; Provisional
Pssm-ID: 235097 [Multi-domain]
Cd Length: 726
Bit Score: 1544.74
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 1 MT D RV S VG N L RI A R VLYDFVNNEALPGT DI D P D S FWAG VDKV V A DL T P Q N Q ALL NA RDELQA Q ID K WHR RRVIE P I D MD A 80
Cdd:PRK02999 1 MT E RV Q VG G L QV A A VLYDFVNNEALPGT GV D A D A FWAG FAAI V H DL A P K N R ALL AK RDELQA K ID A WHR AHPGP P H D LA A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 81 Y RQ FLTEIGYL L PEP D DFTITT SG VD A EI T T T AGPQLVVPV L NAR F ALNAANARWGSLYDALYGTD V IPE TD GAEKG PT Y 160
Cdd:PRK02999 81 Y KA FLTEIGYL V PEP E DFTITT EN VD P EI A T Q AGPQLVVPV M NAR Y ALNAANARWGSLYDALYGTD A IPE EG GAEKG KG Y 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 161 N K VRG D KVIAYAR K FLD DSV PL S SGS FG D A TG FT V Q DGQLVV A L P D - KS TGLA N P G QF A GY T G A A ES P TSV LL I N H GLHI 239
Cdd:PRK02999 161 N P VRG A KVIAYAR A FLD EAA PL A SGS HA D V TG YA V E DGQLVV T L K D g SE TGLA D P A QF V GY Q G D A AA P SAI LL K N N GLHI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 240 EI L ID PESQV G T TD R AGVKDV I LESA I TTIMD F EDSVAAVDA A DKVL G YRNWLGL N KGDL AAAVD K D G TA F L R V LN R DR N 319
Cdd:PRK02999 241 EI Q ID RNHPI G K TD P AGVKDV V LESA L TTIMD C EDSVAAVDA E DKVL V YRNWLGL M KGDL TEEFE K G G KT F T R R LN P DR E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 320 YTAP G GG QF TL P GRSL M FVRNVGHLMTN D AI V D T DG S E VF EGI M DA LF T G LIA I H G LK A sdv NG PLI NSRTGS I YIVKPK 399
Cdd:PRK02999 321 YTAP D GG EL TL H GRSL L FVRNVGHLMTN P AI L D A DG N E IP EGI L DA VV T S LIA L H D LK G --- NG RRR NSRTGS V YIVKPK 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 400 MHGP A EVAF TC ELF S RVED V LGLP Q NT M K I GIMDEERRT T VNLKACI K AA A DRVVFINTGFLDRTGDEIHTSMEAGPMVR 479
Cdd:PRK02999 398 MHGP E EVAF AN ELF G RVED L LGLP R NT L K V GIMDEERRT S VNLKACI R AA K DRVVFINTGFLDRTGDEIHTSMEAGPMVR 477
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 480 KG T MKS Q PWI L AYED H NVD A GLA A G FS GRAQ V GKGMW T M TE LMADM V E T KIA Q P R AGA S TAWVPSPTAATLHALHYHQVD 559
Cdd:PRK02999 478 KG D MKS S PWI A AYED N NVD I GLA C G LR GRAQ I GKGMW A M PD LMADM L E Q KIA H P K AGA N TAWVPSPTAATLHALHYHQVD 557
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 560 V A AVQ QG LA GK R - RA TIEQ LLTIPLA KELA W APD EI RE E V DNN C Q S ILGYVVRWVDQGVGCSKVPDIHDV A LMEDRATLR 638
Cdd:PRK02999 558 V F AVQ AE LA KT R p RA SLDD LLTIPLA ENAN W SAE EI QQ E L DNN A Q G ILGYVVRWVDQGVGCSKVPDIHDV G LMEDRATLR 637
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 639 ISSQ LL ANWLRHGV I T SAD V RA SL E RMA PL VD R QNAGD V AYRPMAP N FD D SIAF L AA QE L ILS G AQH PNGYTEP I LH R RR 718
Cdd:PRK02999 638 ISSQ HI ANWLRHGV V T EEQ V ME SL K RMA AV VD Q QNAGD P AYRPMAP D FD N SIAF Q AA CD L VFK G REQ PNGYTEP L LH A RR 717
....*...
gi 801449671 719 R E F KA RA A 726
Cdd:PRK02999 718 L E A KA KQ A 725
malate_synt_G
cd00728 Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate ...
9-722
0e+00
Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238370 [Multi-domain]
Cd Length: 712
Bit Score: 1420.64
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 9 NLR I A RV LYDFVN N EALPGT D ID P D S FWAG V D KV V A DLTP Q N Q ALL NA RDELQA Q ID K WHR RRVIE P I D MD AY RQ FL T EI 88
Cdd:cd00728 1 NLR V A GC LYDFVN E EALPGT G ID A D A FWAG F D EI V H DLTP R N R ALL AK RDELQA K ID D WHR DNPGP P L D QA AY KK FL K EI 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 89 GYL L PEP D DFTITT SG VD A EI T T T AGPQLVVP VL NAR F ALNAANARWGSLYDALYGTDVIPE TD GAE K G PT YN K VRG D KV 168
Cdd:cd00728 81 GYL V PEP A DFTITT DN VD D EI A T Q AGPQLVVP LM NAR Y ALNAANARWGSLYDALYGTDVIPE EN GAE R G KG YN P VRG A KV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 169 IAYAR K FLD D SVPL SS GS FG DATG FT V Q DGQLVV A L P D - K S T G L AN P G QF A GY T G A A ES P TS VLL INH GLHIEI L ID PES 247
Cdd:cd00728 161 IAYAR R FLD E SVPL TN GS HA DATG YK V V DGQLVV T L D D g K T T T L KD P A QF V GY R G D A NA P SA VLL KHN GLHIEI Q ID RNH 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 248 Q V G T TD R AGVKDV IL E S A I TTIMD F EDSVAAVDA A DKVL G YRNWLGL N KGDLA AA V D K D G TA F L R V LN R DRNYT A P G GG Q 327
Cdd:cd00728 241 Q I G K TD P AGVKDV VV E A A L TTIMD C EDSVAAVDA E DKVL V YRNWLGL M KGDLA EE V E K N G RT F T R K LN A DRNYT T P D GG E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 328 F TLPGRSLMFVRNVGHLMTNDAI V D T DG S EV F EGIMDA LF T G LIA I H G LK A sdv N GPLI NSRTGSIYIVKPKMHGP A EVA 407
Cdd:cd00728 321 I TLPGRSLMFVRNVGHLMTNDAI L D S DG N EV P EGIMDA VI T S LIA L H D LK G --- N SAFG NSRTGSIYIVKPKMHGP E EVA 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 408 F TC ELFSRVED V LGLPQNT M K I GIMDEERRT T VNLK A CI K AA A DRVVFINTGFLDRTGDEIHTSMEAGPM V RK GT MKS Q P 487
Cdd:cd00728 398 F AN ELFSRVED L LGLPQNT I K M GIMDEERRT S VNLK E CI R AA R DRVVFINTGFLDRTGDEIHTSMEAGPM A RK AD MKS S P 477
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 488 WI L AYED H NVD A GLAAG F SG R AQ V GKGMW T M TE LMADM V E T KIA Q P R AGA S TAWVPSPTAATLHALHYHQV D V A AVQ QG L 567
Cdd:cd00728 478 WI G AYED N NVD I GLAAG L SG K AQ I GKGMW A M PD LMADM M E Q KIA H P K AGA N TAWVPSPTAATLHALHYHQV N V F AVQ KE L 557
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 568 A GK R R A TIEQ LLTIPLA KELA W A P D EI RE E V DNN C Q S ILGYVVRWVDQG V GCSKVPDI HD V A LMEDRATLRISSQ LL ANW 647
Cdd:cd00728 558 A KR R P A DLDD LLTIPLA ENAN W S P Q EI QS E L DNN V Q G ILGYVVRWVDQG I GCSKVPDI NN V G LMEDRATLRISSQ HI ANW 637
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 801449671 648 LRHG VI T SAD V RA SLERMA PL VD R QNAGD VA YRPMAP N FDDSIAF L AA QE LI LS G AQH PNGYTEP I LH R RR R E F K 722
Cdd:cd00728 638 LRHG IC T KEQ V QE SLERMA KV VD Q QNAGD PS YRPMAP D FDDSIAF K AA CD LI FQ G KEQ PNGYTEP L LH A RR L E K K 712
malate_syn_G
TIGR01345 malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase ...
4-724
0e+00
malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase and malate synthase form the glyoxylate shunt, which generates additional TCA cycle intermediates. [Energy metabolism, TCA cycle]
Pssm-ID: 130412 [Multi-domain]
Cd Length: 721
Bit Score: 1121.16
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 4 RVSV G N L RI A RV L YD FV NN E A LPGT DI D PDS FW A G V D KV V A DL T P Q N QA LL NA RDE L QA Q ID K WHR RRV i E PID MD AY RQ 83
Cdd:TIGR01345 2 TITQ G R L QV A AN L KR FV DE E V LPGT GL D AAA FW S G F D EI V H DL A P E N RQ LL AE RDE I QA A ID E WHR SNP - G PID KA AY KS 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 84 FL T EIGYL L P E P DDF TI T T SG VD A EIT TT AGPQLVVP VL NAR F ALNAANARWGSLYDALYG TDV IPE T DG A EKG PT YN KV 163
Cdd:TIGR01345 81 FL R EIGYL V P Q P ERV TI E T TN VD S EIT SQ AGPQLVVP AM NAR Y ALNAANARWGSLYDALYG SNI IPE E DG M EKG KE YN PQ 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 164 RG D KVIA YA R K FLD D S V PL SS GS FG D ATGFTVQ D G QL VVA L - PD K S T G L AN P G QF A GY T G A A ES PT SV LL I N H GLHIE IL 242
Cdd:TIGR01345 161 RG E KVIA WV R R FLD E S L PL EN GS HQ D VVAYKIV D K QL RIQ L k NG K E T R L KT P A QF V GY R G D A AD PT CI LL K N N GLHIE LQ 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 243 ID PESQV G TT D R A GV KD VI LESAITTIMD F EDSVAAVDA A DK V L G YRNWLGL NK G D L AAAVD K D G TAFL R V LN R DR N YTA 322
Cdd:TIGR01345 241 ID ANHPI G KD D P A HI KD IV LESAITTIMD C EDSVAAVDA E DK I L L YRNWLGL MQ G T L QEKME K N G RQIV R K LN D DR H YTA 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 323 PG G GQFT L P GRSL M FVRNVGHLMT NDA I V D TD G S E VF EGI M D ALF TG L IA IHG LK asd V NGPLI NSR T GS I YIVKPKMHG 402
Cdd:TIGR01345 321 AN G SEIS L H GRSL L FVRNVGHLMT IPV I W D SE G E E IP EGI L D GVM TG A IA LYD LK --- V QNKMR NSR K GS V YIVKPKMHG 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 403 P A EVAF TCE LF S R V ED V LGL PQN T M K I G I MDEERRT TV NL K ACI KAAAD RV V FINTGFLDRTGDEIHTSMEAGPM V RK GT 482
Cdd:TIGR01345 398 P E EVAF ANK LF T R I ED M LGL ARH T L K M G V MDEERRT SL NL R ACI AQVRN RV A FINTGFLDRTGDEIHTSMEAGPM L RK ND 477
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 483 MKS Q PWI L AYE DH NV D AGL AA G FS G R AQ V GKGMW T M TE LMA D M V E T K IA Q P RAGA S TAWVPSPTAATLHALHYHQ VD V AA 562
Cdd:TIGR01345 478 MKS T PWI K AYE RN NV L AGL FC G LR G K AQ I GKGMW A M PD LMA E M Y E Q K GD Q L RAGA N TAWVPSPTAATLHALHYHQ TN V QS 557
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 563 VQ QG LA - GKRR A TIEQL LTIP L A KELA W APD EI RE E V DNN C Q S ILGYVVRWV D QG V GCSKVPDIH D VALMEDRATLRISS 641
Cdd:TIGR01345 558 VQ AN LA q TEFN A ELDDI LTIP V A ENTN W SAE EI QQ E L DNN V Q G ILGYVVRWV E QG I GCSKVPDIH N VALMEDRATLRISS 637
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 642 Q LL ANWLRHG VITSAD V R ASLERMA PL VD R QNAGD V AYRPMA P NF DD S I AF L AA QE LI LS G AQH P N GYTEPILH R RR R EF 721
Cdd:TIGR01345 638 Q HI ANWLRHG IVSKEQ V Q ASLERMA KV VD Q QNAGD P AYRPMA G NF AN S C AF Q AA SD LI FL G TKQ P S GYTEPILH A RR L EF 717
...
gi 801449671 722 K AR 724
Cdd:TIGR01345 718 K EK 720
Malate_synthase
pfam01274 Malate synthase;
17-699
0e+00
Malate synthase;
Pssm-ID: 426172
Cd Length: 523
Bit Score: 572.80
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 17 YDFV NNEA LPGT D I DPDSFWAG V DKVVA D L TP QNQA LL NA RDE L QA Q ID KW H rrrviepidmda YRQ FL T E I GY LL P E PD 96
Cdd:pfam01274 1 YDFV GPYV LPGT G I LTKEALSF V AELHR D F TP RRRE LL AR RDE R QA R ID AG H ------------ LPD FL P E T GY IR P D PD 68
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 97 DF T I T tsgvdaeitttagpqlvvpvlnarfalnaanarwgslydalygtdvipetdgaekgptynkvrgdkviayarkfl 176
Cdd:pfam01274 69 WK T A T --------------------------------------------------------------------------- 73
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 177 ddsvplssgsfgdatgftvqdgqlvvalpdkstglanpgqfagytgaaesptsvllinhg LH I E ILIDPESQV G TT DR AG 256
Cdd:pfam01274 74 ------------------------------------------------------------ LH P E LQDRRVEIT G PA DR KM 93
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 257 VKDVILES AITT IM DFEDSVA A vdaadkvlgyr N W LG L NK G D L AAAVDKD G TAFL R V LN RDRN Y TAPG G gqft L P GR SLM 336
Cdd:pfam01274 94 IINALNSG AITT MA DFEDSVA P ----------- T W NN L IQ G Q L NLYDAVR G RIDF R D LN AGKS Y KLND G ---- L H GR ATL 158
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 337 FVR NV G HLMTNDA I V d T DG SEVFE GI M D A lft GL IAI H GL K A sdvngpl I NSR T G SI Y IVK PKM HGPA E V A FTCEL F S R V 416
Cdd:pfam01274 159 FVR PR G WHLPEKH I L - V DG EPIPG GI F D F --- GL YFF H NA K E ------- L NSR G G GP Y FYL PKM EHHQ E A A LWNDV F N R A 227
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 417 ED V LG L P QN T MKIGIMD E ERRTTVNLKAC I KAAA D RVVFI N T G FL D RTGDE I H T SME A GP MV --- RK GTMKSQ P WIL AYE 493
Cdd:pfam01274 228 ED Y LG I P RG T IRATVLI E TLPASFQMDEI I YELR D HSAGL N C G RW D YIFSY I K T LRN A PD MV lpd RK AVTMTA P FMR AYE 307
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 494 DHNVD ------ AGLAA G FSGRAQVGKG M WTM T EL M ADMVET K IAQP RAG ASTA WV PS P TA A T L H A LHY HQV D V AAV Q QG L 567
Cdd:pfam01274 308 KLLIK tchkrg VHAMG G MAAQIPIKDD M EAN T AA M EKVRAD K LREV RAG HDGT WV AH P GL A P L A A EVF HQV M V RPN Q IE L 387
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 568 A GKR - RA T IEQ LLTIP LAK elawapd E IR E EVD NN C Q SI L G YV VR W V d Q G V GC sk VP D IH dva LMED R AT LR IS S Q L L AN 646
Cdd:pfam01274 388 A REE d SI T ADD LLTIP DGE ------- E TE E GLR NN I Q VG L Q YV EA W L - R G S GC -- VP I IH --- LMED A AT AE IS R Q Q L WQ 454
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 801449671 647 WLRHGV ITSAD VR AS LE R MA P LVD RQ NA ------- GD V AYR PM --------- A PNF DD SIAF LA AQE LI 699
Cdd:pfam01274 455 WLRHGV TLDEG VR VT LE L MA K LVD EE NA rlakerf GD G AYR DA arlflqqat A EEY DD FLTL LA YDD LI 523
AceB
COG2225 Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway ...
574-655
6.16e-03
Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway/BioSystem: TCA cycle, glyoxylate bypass
Pssm-ID: 441827
Cd Length: 530
Bit Score: 39.70
E-value: 6.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 574 T IEQ LL TI P lakelawa PDE I R E E - VD NN CQSILG Y VVR W V d Q G V G C sk VP d I HD va LMED R AT LR IS - SQ LL a N W LR HG 651
Cdd:COG2225 398 T AAD LL DV P -------- EGT I T E A g LR NN ISVGIQ Y LEA W L - R G N G A -- VP - I YN -- LMED A AT AE IS r SQ VW - Q W IH HG 462
....
gi 801449671 652 VITS 655
Cdd:COG2225 463 ATLD 466
Name
Accession
Description
Interval
E-value
PRK02999
PRK02999 malate synthase G; Provisional
1-726
0e+00
malate synthase G; Provisional
Pssm-ID: 235097 [Multi-domain]
Cd Length: 726
Bit Score: 1544.74
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 1 MT D RV S VG N L RI A R VLYDFVNNEALPGT DI D P D S FWAG VDKV V A DL T P Q N Q ALL NA RDELQA Q ID K WHR RRVIE P I D MD A 80
Cdd:PRK02999 1 MT E RV Q VG G L QV A A VLYDFVNNEALPGT GV D A D A FWAG FAAI V H DL A P K N R ALL AK RDELQA K ID A WHR AHPGP P H D LA A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 81 Y RQ FLTEIGYL L PEP D DFTITT SG VD A EI T T T AGPQLVVPV L NAR F ALNAANARWGSLYDALYGTD V IPE TD GAEKG PT Y 160
Cdd:PRK02999 81 Y KA FLTEIGYL V PEP E DFTITT EN VD P EI A T Q AGPQLVVPV M NAR Y ALNAANARWGSLYDALYGTD A IPE EG GAEKG KG Y 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 161 N K VRG D KVIAYAR K FLD DSV PL S SGS FG D A TG FT V Q DGQLVV A L P D - KS TGLA N P G QF A GY T G A A ES P TSV LL I N H GLHI 239
Cdd:PRK02999 161 N P VRG A KVIAYAR A FLD EAA PL A SGS HA D V TG YA V E DGQLVV T L K D g SE TGLA D P A QF V GY Q G D A AA P SAI LL K N N GLHI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 240 EI L ID PESQV G T TD R AGVKDV I LESA I TTIMD F EDSVAAVDA A DKVL G YRNWLGL N KGDL AAAVD K D G TA F L R V LN R DR N 319
Cdd:PRK02999 241 EI Q ID RNHPI G K TD P AGVKDV V LESA L TTIMD C EDSVAAVDA E DKVL V YRNWLGL M KGDL TEEFE K G G KT F T R R LN P DR E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 320 YTAP G GG QF TL P GRSL M FVRNVGHLMTN D AI V D T DG S E VF EGI M DA LF T G LIA I H G LK A sdv NG PLI NSRTGS I YIVKPK 399
Cdd:PRK02999 321 YTAP D GG EL TL H GRSL L FVRNVGHLMTN P AI L D A DG N E IP EGI L DA VV T S LIA L H D LK G --- NG RRR NSRTGS V YIVKPK 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 400 MHGP A EVAF TC ELF S RVED V LGLP Q NT M K I GIMDEERRT T VNLKACI K AA A DRVVFINTGFLDRTGDEIHTSMEAGPMVR 479
Cdd:PRK02999 398 MHGP E EVAF AN ELF G RVED L LGLP R NT L K V GIMDEERRT S VNLKACI R AA K DRVVFINTGFLDRTGDEIHTSMEAGPMVR 477
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 480 KG T MKS Q PWI L AYED H NVD A GLA A G FS GRAQ V GKGMW T M TE LMADM V E T KIA Q P R AGA S TAWVPSPTAATLHALHYHQVD 559
Cdd:PRK02999 478 KG D MKS S PWI A AYED N NVD I GLA C G LR GRAQ I GKGMW A M PD LMADM L E Q KIA H P K AGA N TAWVPSPTAATLHALHYHQVD 557
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 560 V A AVQ QG LA GK R - RA TIEQ LLTIPLA KELA W APD EI RE E V DNN C Q S ILGYVVRWVDQGVGCSKVPDIHDV A LMEDRATLR 638
Cdd:PRK02999 558 V F AVQ AE LA KT R p RA SLDD LLTIPLA ENAN W SAE EI QQ E L DNN A Q G ILGYVVRWVDQGVGCSKVPDIHDV G LMEDRATLR 637
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 639 ISSQ LL ANWLRHGV I T SAD V RA SL E RMA PL VD R QNAGD V AYRPMAP N FD D SIAF L AA QE L ILS G AQH PNGYTEP I LH R RR 718
Cdd:PRK02999 638 ISSQ HI ANWLRHGV V T EEQ V ME SL K RMA AV VD Q QNAGD P AYRPMAP D FD N SIAF Q AA CD L VFK G REQ PNGYTEP L LH A RR 717
....*...
gi 801449671 719 R E F KA RA A 726
Cdd:PRK02999 718 L E A KA KQ A 725
malate_synt_G
cd00728 Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate ...
9-722
0e+00
Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238370 [Multi-domain]
Cd Length: 712
Bit Score: 1420.64
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 9 NLR I A RV LYDFVN N EALPGT D ID P D S FWAG V D KV V A DLTP Q N Q ALL NA RDELQA Q ID K WHR RRVIE P I D MD AY RQ FL T EI 88
Cdd:cd00728 1 NLR V A GC LYDFVN E EALPGT G ID A D A FWAG F D EI V H DLTP R N R ALL AK RDELQA K ID D WHR DNPGP P L D QA AY KK FL K EI 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 89 GYL L PEP D DFTITT SG VD A EI T T T AGPQLVVP VL NAR F ALNAANARWGSLYDALYGTDVIPE TD GAE K G PT YN K VRG D KV 168
Cdd:cd00728 81 GYL V PEP A DFTITT DN VD D EI A T Q AGPQLVVP LM NAR Y ALNAANARWGSLYDALYGTDVIPE EN GAE R G KG YN P VRG A KV 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 169 IAYAR K FLD D SVPL SS GS FG DATG FT V Q DGQLVV A L P D - K S T G L AN P G QF A GY T G A A ES P TS VLL INH GLHIEI L ID PES 247
Cdd:cd00728 161 IAYAR R FLD E SVPL TN GS HA DATG YK V V DGQLVV T L D D g K T T T L KD P A QF V GY R G D A NA P SA VLL KHN GLHIEI Q ID RNH 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 248 Q V G T TD R AGVKDV IL E S A I TTIMD F EDSVAAVDA A DKVL G YRNWLGL N KGDLA AA V D K D G TA F L R V LN R DRNYT A P G GG Q 327
Cdd:cd00728 241 Q I G K TD P AGVKDV VV E A A L TTIMD C EDSVAAVDA E DKVL V YRNWLGL M KGDLA EE V E K N G RT F T R K LN A DRNYT T P D GG E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 328 F TLPGRSLMFVRNVGHLMTNDAI V D T DG S EV F EGIMDA LF T G LIA I H G LK A sdv N GPLI NSRTGSIYIVKPKMHGP A EVA 407
Cdd:cd00728 321 I TLPGRSLMFVRNVGHLMTNDAI L D S DG N EV P EGIMDA VI T S LIA L H D LK G --- N SAFG NSRTGSIYIVKPKMHGP E EVA 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 408 F TC ELFSRVED V LGLPQNT M K I GIMDEERRT T VNLK A CI K AA A DRVVFINTGFLDRTGDEIHTSMEAGPM V RK GT MKS Q P 487
Cdd:cd00728 398 F AN ELFSRVED L LGLPQNT I K M GIMDEERRT S VNLK E CI R AA R DRVVFINTGFLDRTGDEIHTSMEAGPM A RK AD MKS S P 477
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 488 WI L AYED H NVD A GLAAG F SG R AQ V GKGMW T M TE LMADM V E T KIA Q P R AGA S TAWVPSPTAATLHALHYHQV D V A AVQ QG L 567
Cdd:cd00728 478 WI G AYED N NVD I GLAAG L SG K AQ I GKGMW A M PD LMADM M E Q KIA H P K AGA N TAWVPSPTAATLHALHYHQV N V F AVQ KE L 557
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 568 A GK R R A TIEQ LLTIPLA KELA W A P D EI RE E V DNN C Q S ILGYVVRWVDQG V GCSKVPDI HD V A LMEDRATLRISSQ LL ANW 647
Cdd:cd00728 558 A KR R P A DLDD LLTIPLA ENAN W S P Q EI QS E L DNN V Q G ILGYVVRWVDQG I GCSKVPDI NN V G LMEDRATLRISSQ HI ANW 637
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 801449671 648 LRHG VI T SAD V RA SLERMA PL VD R QNAGD VA YRPMAP N FDDSIAF L AA QE LI LS G AQH PNGYTEP I LH R RR R E F K 722
Cdd:cd00728 638 LRHG IC T KEQ V QE SLERMA KV VD Q QNAGD PS YRPMAP D FDDSIAF K AA CD LI FQ G KEQ PNGYTEP L LH A RR L E K K 712
malate_syn_G
TIGR01345 malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase ...
4-724
0e+00
malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase and malate synthase form the glyoxylate shunt, which generates additional TCA cycle intermediates. [Energy metabolism, TCA cycle]
Pssm-ID: 130412 [Multi-domain]
Cd Length: 721
Bit Score: 1121.16
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 4 RVSV G N L RI A RV L YD FV NN E A LPGT DI D PDS FW A G V D KV V A DL T P Q N QA LL NA RDE L QA Q ID K WHR RRV i E PID MD AY RQ 83
Cdd:TIGR01345 2 TITQ G R L QV A AN L KR FV DE E V LPGT GL D AAA FW S G F D EI V H DL A P E N RQ LL AE RDE I QA A ID E WHR SNP - G PID KA AY KS 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 84 FL T EIGYL L P E P DDF TI T T SG VD A EIT TT AGPQLVVP VL NAR F ALNAANARWGSLYDALYG TDV IPE T DG A EKG PT YN KV 163
Cdd:TIGR01345 81 FL R EIGYL V P Q P ERV TI E T TN VD S EIT SQ AGPQLVVP AM NAR Y ALNAANARWGSLYDALYG SNI IPE E DG M EKG KE YN PQ 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 164 RG D KVIA YA R K FLD D S V PL SS GS FG D ATGFTVQ D G QL VVA L - PD K S T G L AN P G QF A GY T G A A ES PT SV LL I N H GLHIE IL 242
Cdd:TIGR01345 161 RG E KVIA WV R R FLD E S L PL EN GS HQ D VVAYKIV D K QL RIQ L k NG K E T R L KT P A QF V GY R G D A AD PT CI LL K N N GLHIE LQ 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 243 ID PESQV G TT D R A GV KD VI LESAITTIMD F EDSVAAVDA A DK V L G YRNWLGL NK G D L AAAVD K D G TAFL R V LN R DR N YTA 322
Cdd:TIGR01345 241 ID ANHPI G KD D P A HI KD IV LESAITTIMD C EDSVAAVDA E DK I L L YRNWLGL MQ G T L QEKME K N G RQIV R K LN D DR H YTA 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 323 PG G GQFT L P GRSL M FVRNVGHLMT NDA I V D TD G S E VF EGI M D ALF TG L IA IHG LK asd V NGPLI NSR T GS I YIVKPKMHG 402
Cdd:TIGR01345 321 AN G SEIS L H GRSL L FVRNVGHLMT IPV I W D SE G E E IP EGI L D GVM TG A IA LYD LK --- V QNKMR NSR K GS V YIVKPKMHG 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 403 P A EVAF TCE LF S R V ED V LGL PQN T M K I G I MDEERRT TV NL K ACI KAAAD RV V FINTGFLDRTGDEIHTSMEAGPM V RK GT 482
Cdd:TIGR01345 398 P E EVAF ANK LF T R I ED M LGL ARH T L K M G V MDEERRT SL NL R ACI AQVRN RV A FINTGFLDRTGDEIHTSMEAGPM L RK ND 477
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 483 MKS Q PWI L AYE DH NV D AGL AA G FS G R AQ V GKGMW T M TE LMA D M V E T K IA Q P RAGA S TAWVPSPTAATLHALHYHQ VD V AA 562
Cdd:TIGR01345 478 MKS T PWI K AYE RN NV L AGL FC G LR G K AQ I GKGMW A M PD LMA E M Y E Q K GD Q L RAGA N TAWVPSPTAATLHALHYHQ TN V QS 557
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 563 VQ QG LA - GKRR A TIEQL LTIP L A KELA W APD EI RE E V DNN C Q S ILGYVVRWV D QG V GCSKVPDIH D VALMEDRATLRISS 641
Cdd:TIGR01345 558 VQ AN LA q TEFN A ELDDI LTIP V A ENTN W SAE EI QQ E L DNN V Q G ILGYVVRWV E QG I GCSKVPDIH N VALMEDRATLRISS 637
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 642 Q LL ANWLRHG VITSAD V R ASLERMA PL VD R QNAGD V AYRPMA P NF DD S I AF L AA QE LI LS G AQH P N GYTEPILH R RR R EF 721
Cdd:TIGR01345 638 Q HI ANWLRHG IVSKEQ V Q ASLERMA KV VD Q QNAGD P AYRPMA G NF AN S C AF Q AA SD LI FL G TKQ P S GYTEPILH A RR L EF 717
...
gi 801449671 722 K AR 724
Cdd:TIGR01345 718 K EK 720
Malate_synthase
pfam01274 Malate synthase;
17-699
0e+00
Malate synthase;
Pssm-ID: 426172
Cd Length: 523
Bit Score: 572.80
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 17 YDFV NNEA LPGT D I DPDSFWAG V DKVVA D L TP QNQA LL NA RDE L QA Q ID KW H rrrviepidmda YRQ FL T E I GY LL P E PD 96
Cdd:pfam01274 1 YDFV GPYV LPGT G I LTKEALSF V AELHR D F TP RRRE LL AR RDE R QA R ID AG H ------------ LPD FL P E T GY IR P D PD 68
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 97 DF T I T tsgvdaeitttagpqlvvpvlnarfalnaanarwgslydalygtdvipetdgaekgptynkvrgdkviayarkfl 176
Cdd:pfam01274 69 WK T A T --------------------------------------------------------------------------- 73
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 177 ddsvplssgsfgdatgftvqdgqlvvalpdkstglanpgqfagytgaaesptsvllinhg LH I E ILIDPESQV G TT DR AG 256
Cdd:pfam01274 74 ------------------------------------------------------------ LH P E LQDRRVEIT G PA DR KM 93
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 257 VKDVILES AITT IM DFEDSVA A vdaadkvlgyr N W LG L NK G D L AAAVDKD G TAFL R V LN RDRN Y TAPG G gqft L P GR SLM 336
Cdd:pfam01274 94 IINALNSG AITT MA DFEDSVA P ----------- T W NN L IQ G Q L NLYDAVR G RIDF R D LN AGKS Y KLND G ---- L H GR ATL 158
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 337 FVR NV G HLMTNDA I V d T DG SEVFE GI M D A lft GL IAI H GL K A sdvngpl I NSR T G SI Y IVK PKM HGPA E V A FTCEL F S R V 416
Cdd:pfam01274 159 FVR PR G WHLPEKH I L - V DG EPIPG GI F D F --- GL YFF H NA K E ------- L NSR G G GP Y FYL PKM EHHQ E A A LWNDV F N R A 227
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 417 ED V LG L P QN T MKIGIMD E ERRTTVNLKAC I KAAA D RVVFI N T G FL D RTGDE I H T SME A GP MV --- RK GTMKSQ P WIL AYE 493
Cdd:pfam01274 228 ED Y LG I P RG T IRATVLI E TLPASFQMDEI I YELR D HSAGL N C G RW D YIFSY I K T LRN A PD MV lpd RK AVTMTA P FMR AYE 307
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 494 DHNVD ------ AGLAA G FSGRAQVGKG M WTM T EL M ADMVET K IAQP RAG ASTA WV PS P TA A T L H A LHY HQV D V AAV Q QG L 567
Cdd:pfam01274 308 KLLIK tchkrg VHAMG G MAAQIPIKDD M EAN T AA M EKVRAD K LREV RAG HDGT WV AH P GL A P L A A EVF HQV M V RPN Q IE L 387
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 568 A GKR - RA T IEQ LLTIP LAK elawapd E IR E EVD NN C Q SI L G YV VR W V d Q G V GC sk VP D IH dva LMED R AT LR IS S Q L L AN 646
Cdd:pfam01274 388 A REE d SI T ADD LLTIP DGE ------- E TE E GLR NN I Q VG L Q YV EA W L - R G S GC -- VP I IH --- LMED A AT AE IS R Q Q L WQ 454
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 801449671 647 WLRHGV ITSAD VR AS LE R MA P LVD RQ NA ------- GD V AYR PM --------- A PNF DD SIAF LA AQE LI 699
Cdd:pfam01274 455 WLRHGV TLDEG VR VT LE L MA K LVD EE NA rlakerf GD G AYR DA arlflqqat A EEY DD FLTL LA YDD LI 523
malate_synt
cd00480 Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , ...
35-718
0e+00
Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238267
Cd Length: 511
Bit Score: 549.14
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 35 FW A G V DKVVADLT P QNQA LL N ARDE L QA QI D KW H rrrviepidmd A YRQ FL T E IG Y L l PEPD D FTITTS -- GV D AEITTT 112
Cdd:cd00480 1 AL A F V AELHREFN P RRRE LL A ARDE R QA RL D AG H ----------- A LPD FL P E TA Y I - RRDG D WKVAPD pp DL D DRRVEI 68
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 113 A GPQ LVVP V L NA RFALN A anarwgslydalygtdvipetdgaekgptynkvrgdkviayarkflddsvplssgsfgdatg 192
Cdd:cd00480 69 T GPQ DRKM V I NA LNSGA A -------------------------------------------------------------- 86
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 193 ftvqdgqlvvalpdkstglanpgqfagytgaaesptsvllinhglhieilidpesqvgttdragvkdvilesai TTIM DF 272
Cdd:cd00480 87 -------------------------------------------------------------------------- VFMA DF 92
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 273 EDS V A AV d AAD KV L G Y RN W L GLNK G DLAAAVD K D G TAFLRV L nrdrnytapgggqft L P GR SLM FVR NV G HLM T NDA I VD 352
Cdd:cd00480 93 EDS S A PT - WEN KV E G Q RN L L DAVR G TISFTDS K N G KSYRLN L --------------- L D GR ATL FVR PR G WHL T EKH I LV 156
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 353 t DG SE V FE G IM D ALFTGLIAI H G LKA sdvngplins R TGSI Y IVK PKM HG P A E VAFTCEL FSR V ED V LGLP QN T M K IGIM 432
Cdd:cd00480 157 - DG EP V PG G LF D FGLYFFHNA H A LKA ---------- R GSGP Y FYL PKM ES P L E ARLWNDV FSR A ED Y LGLP RG T I K ATVL 225
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 433 D E ERRTTVNLKACIKAAA D RVVFI N T G FL D RTGD EI H T SM ---- EAG P MVR K G TM k SQ P WIL AYE DHN V DAGLAA G F --- 505
Cdd:cd00480 226 I E TLPAAFEMDEILYELR D HSAGL N C G RW D YIFS EI K T FR nhpd FVL P DRA K V TM - TS P FMR AYE KLL V KTCHRR G A ham 304
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 506 - SGR AQ VG - KG MWTMT E - L MA DMVET K IAQPR AG ASTA WV PS P TA A T L H AL HY H Q V DVAAV Q QGLAGKR - RA T IEQ LLTI 581
Cdd:cd00480 305 g GMA AQ IP i KG DPAAN E a A MA KVRAD K LREAK AG HDGT WV AH P GL A P L A AL VF H K V MPGPN Q LFRKRED v KV T ADD LLTI 384
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 582 P L A kelaw AP D EIR E EVD NN C Q SI LGYVV R W VD qgv G CSK VP D I H dva LMED R AT LR IS SQL L AN WLRHGV ITSAD V RAS 661
Cdd:cd00480 385 P V A ----- EG D ITE E GLR NN I Q VA LGYVV A W LN --- G NGA VP I I N --- LMED A AT AE IS RSQ L WQ WLRHGV CLDDG V PVT 453
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 662 LE RM A P LVD RQ NA GDV AYRP ma PNF D DSIAF LA A QE L ILS G AQH --- P NGY TEP IL H RR R 718
Cdd:cd00480 454 LE LV A K LVD EE NA RLP AYRP -- PNF F DSIAF KE A AD L FFE G VTA eef P EFL TEP LY H LL R 511
PRK08951
PRK08951 malate synthase; Provisional
169-330
1.04e-24
malate synthase; Provisional
Pssm-ID: 181593 [Multi-domain]
Cd Length: 190
Bit Score: 102.02
E-value: 1.04e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 169 I A Y A RK FLD DSV PL SS GS FG D ATGFT V QDGQ L VVALP D K S - T GL AN P G QF AGYT G AAES P TSV LL INH G L H I E ILI D PES 247
Cdd:PRK08951 38 Q A K A KQ FLD RLF PL AN GS HQ D VSSYV V YYQH L LAFFA D G S h S GL RQ P K QF VAFN G HKSE P SAI LL KDS G S H V E LTF D RHG 117
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 248 QV G TT D R A GVK D VI LE SAI T TIMDFEDSVAA vdaadkvl GY R N W LG L N KGD LAAAVDK D G taflrvln R D RNY TA PG G GQ 327
Cdd:PRK08951 118 GT G SR D L A NIE D IQ LE TCT T FSQEPTENRST -------- AM R H W IS L L KGD ESGRPAA D Q -------- E D KEF TA KD G SD 181
...
gi 801449671 328 FT L 330
Cdd:PRK08951 182 YQ L 184
malate_synt_A
cd00727 Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to ...
238-652
5.32e-06
Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA, which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238369
Cd Length: 511
Bit Score: 49.56
E-value: 5.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 238 HI EI lidpesq V G TT DR agv K D VI -- L E S AITTI M - DFED SV A A vdaadkvlgyr N W LGLNK G -- D L AA AV D kdgtaflr 312
Cdd:cd00727 68 RV EI ------- T G PV DR --- K M VI na L N S GAKVF M a DFED AN A P ----------- T W ENQVE G qi N L RD AV R -------- 118
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 313 vln RDRNY T A P G G GQFT L - PGRSLMF VR NV G - HL MTNDAI VD td G SE V FEGIM D A lft GL IAI H GL KA sdvngp L INSRT 390
Cdd:cd00727 119 --- GTISF T S P E G KEYK L n DTPATLI VR PR G w HL PEKHVL VD -- G EP V SGSLF D F --- GL YFF H NA KA ------ L LARGS 184
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 391 G s I Y IVK PKM HGPA E VAFTCEL F SRVE D V LGLP QN T M K IGI ---------- MDE --- E - R RTTVN L KA -------- C IK A 448
Cdd:cd00727 185 G - P Y FYL PKM ESHL E ARLWNDV F VFAQ D Y LGLP RG T I K ATV lietlpaafe MDE ily E l R DHSAG L NC grwdyifs F IK K 263
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 449 AADRVV F I ntg FL DR T gdeihtsmeagpmvr KG TM k SQ P WIL AY ED ------ H NVD A GLAA G FS gr AQ V - G K GMWTMT E L 521
Cdd:cd00727 264 FRNHPD F V --- LP DR A --------------- QV TM - TV P FMR AY SE lliktc H RRG A HAMG G MA -- AQ I p I K DDPAAN E A 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 522 - M A DMVET K IAQPR AG ASTA WV PS P TAA ------- TL H ALHYH Q V DV aavqqg L AGKRRA T IEQ LL TI P lakelaw APDE 593
Cdd:cd00727 323 a L A KVRAD K LREAT AG HDGT WV AH P GLV pvamevf DK H MPGPN Q L DV ------ L REDVKV T AAD LL LV P ------- VEGG 389
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 594 I R EE - VDN N CQSI L G Y VVR W V d Q G V GC sk VP d I HD va LMED R AT LR IS SQL L AN W L RHGV 652
Cdd:cd00727 390 I T EE g LRQ N ISVG L Q Y LAA W L - R G N GC -- VP - I YN -- LMED A AT AE IS RAQ L WQ W I RHGV 443
PLN02626
PLN02626 malate synthase
250-672
9.72e-06
malate synthase
Pssm-ID: 215336
Cd Length: 551
Bit Score: 49.00
E-value: 9.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 250 G TTD R agv K D VI -- L E S AITTI M - DFEDS VAA vdaadkvlgyr N W LG L NK G -- D L AA AV dkdgtaflrvl NRDRNY T - AP 323
Cdd:PLN02626 97 G PVE R --- K M VI na L N S GAKVF M a DFEDS LSP ----------- T W EN L MR G qv N L RD AV ----------- RGTITF T d KA 151
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 324 G G GQFT L PGR - SLM FVR NV G - HL mt ND A IVDT DG s E VFE G imd A LF T - GL IAI H G ---- LKASDVN GP linsrtgsi YIV 396
Cdd:PLN02626 152 R G KVYK L NDK t AKL FVR PR G w HL -- PE A HILV DG - E PAT G --- S LF D f GL YFF H N yaaf RAKQGGF GP --------- FFY 216
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 397 K PKM HGPA E VAFTCEL F SRV E DVL G L P QNTMKIGIMD E ERRTTVNLKACIKAAA D RVVFI N T G FL D R ------------- 463
Cdd:PLN02626 217 L PKM EHSR E ARLWNDV F EAA E KMA G I P RGSIRATVLI E TLPAVFQMEEILYELR D HSAGL N C G RW D Y ifsfvktfrahpd 296
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 464 -- TG D EIHTS M e AGPM vrkgt MKS QPWI L AYED H N -- V D A -- G L AA GFSGRAQVGKGMWTMTELMA D mvet K IAQP RAG A 537
Cdd:PLN02626 297 rl LP D RVQVG M - TQHF ----- MKS YVDL L IKTC H K rg V H A mg G M AA QIPIKDDPAANEAALALVRK D ---- K LREV RAG H 366
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 538 STA W VPS P -- TAATLHALHY H q VDVAAV QQ GLAGKRRATI -- EQ LL TI P LAKELA wapdeir E EVDN N CQSILG Y VVR W V 613
Cdd:PLN02626 367 DGT W AAH P gl IPLAMEVFDG H - MPTPNN QQ LHKRRDDVNV te AD LL QV P RGVRTL ------- E GLRL N TRVGIQ Y LAA W L 438
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 801449671 614 d Q G V G C sk VP d IHD va LMED R AT LR IS SQLLAN W LRH G VITSA D --- VR ASL E RMAPL V DRQ 672
Cdd:PLN02626 439 - T G T G S -- VP - LYN -- LMED A AT AE IS RVQNWQ W IKY G AELDG D gvg VR VTA E LFGRV V EEE 494
AceB
COG2225 Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway ...
574-655
6.16e-03
Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway/BioSystem: TCA cycle, glyoxylate bypass
Pssm-ID: 441827
Cd Length: 530
Bit Score: 39.70
E-value: 6.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801449671 574 T IEQ LL TI P lakelawa PDE I R E E - VD NN CQSILG Y VVR W V d Q G V G C sk VP d I HD va LMED R AT LR IS - SQ LL a N W LR HG 651
Cdd:COG2225 398 T AAD LL DV P -------- EGT I T E A g LR NN ISVGIQ Y LEA W L - R G N G A -- VP - I YN -- LMED A AT AE IS r SQ VW - Q W IH HG 462
....
gi 801449671 652 VITS 655
Cdd:COG2225 463 ATLD 466
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
