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Conserved domains on  [gi|886166823|emb|CLM01972|]
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exodeoxyribonuclease VII small subunit [Mycobacterium tuberculosis]

Protein Classification

exodeoxyribonuclease VII small subunit( domain architecture ID 10011590)

small subunit of exodeoxyribonuclease VII, which degrades single-stranded DNA bidirectionally into nucleoside 5'-phosphates

EC:  3.1.11.6
Gene Ontology:  GO:0008855|GO:0004527|GO:0006308
PubMed:  6284744
SCOP:  4002913

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK00977 PRK00977
exodeoxyribonuclease VII small subunit; Provisional
 13-81 1.07e-22

exodeoxyribonuclease VII small subunit; Provisional


:

Pssm-ID: 179195  Cd Length: 80  Bit Score: 82.65  E-value: 1.07e-22
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 886166823 13 THATVPVSQLGYEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVSDVLAGDE 81
Cdd:PRK00977  1 TMPAKKSKPLSFEEALAELEEIVTRLESGDLPLEESLAAFERGVALARQCQKKLQQAEQRVEKLLDEDG 69
 
Name Accession Description Interval E-value
PRK00977 PRK00977
exodeoxyribonuclease VII small subunit; Provisional
 13-81 1.07e-22

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 179195  Cd Length: 80  Bit Score: 82.65  E-value: 1.07e-22
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 886166823 13 THATVPVSQLGYEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVSDVLAGDE 81
Cdd:PRK00977  1 TMPAKKSKPLSFEEALAELEEIVTRLESGDLPLEESLAAFERGVALARQCQKKLQQAEQRVEKLLDEDG 69
XseB COG1722
Exonuclease VII small subunit [Replication, recombination and repair];
18-83 2.31e-19

Exonuclease VII small subunit [Replication, recombination and repair];


Pssm-ID: 441328  Cd Length: 74  Bit Score: 74.12  E-value: 2.31e-19
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 886166823 18 PVSQLGYEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVSDVLAGDEAQ 83
Cdd:COG1722   1 DKKELSFEEALAELEEIVERLESGELPLEESLALYERGVALAKRCQKKLDEAEQKVEKLLEDEDGE 66
xseB TIGR01280
exodeoxyribonuclease VII, small subunit; This protein is the small subunit for ...
 24-76 9.76e-15

exodeoxyribonuclease VII, small subunit; This protein is the small subunit for exodeoxyribonuclease VII. Exodeoxyribonuclease VII is made of a complex of four small subunits to one large subunit. The complex degrades single-stranded DNA into large acid-insoluble oligonucleotides. These nucleotides are then degraded further into acid-soluble oligonucleotides. [DNA metabolism, Degradation of DNA]


Pssm-ID: 273536  Cd Length: 54  Bit Score: 61.67  E-value: 9.76e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 886166823  24 YEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVSDV 76
Cdd:TIGR01280  2 FEEALAELEEIVEKLESGDLSLEESLKLYEEGIKLLKHCQKKLEEAEQKIEKL 54
Exonuc_VII_S pfam02609
Exonuclease VII small subunit; This family consist of exonuclease VII, small subunit EC:3.1.11. ...
 24-73 2.43e-14

Exonuclease VII small subunit; This family consist of exonuclease VII, small subunit EC:3.1.11.6 This enzyme catalyzes exonucleolytic cleavage in either 5'->3' or 3'->5' direction to yield 5'-phosphomononucleotides. This exonuclease VII enzyme is composed of one large subunit and 4 small ones.


Pssm-ID: 460618  Cd Length: 51  Bit Score: 60.86  E-value: 2.43e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 886166823  24 YEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRV 73
Cdd:pfam02609  1 FEEALAELEEIVEKLESGELSLEESLKLYEEGIKLLKFCEKKLDEAEQKI 50
 
Name Accession Description Interval E-value
PRK00977 PRK00977
exodeoxyribonuclease VII small subunit; Provisional
 13-81 1.07e-22

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 179195  Cd Length: 80  Bit Score: 82.65  E-value: 1.07e-22
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 886166823 13 THATVPVSQLGYEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVSDVLAGDE 81
Cdd:PRK00977  1 TMPAKKSKPLSFEEALAELEEIVTRLESGDLPLEESLAAFERGVALARQCQKKLQQAEQRVEKLLDEDG 69
XseB COG1722
Exonuclease VII small subunit [Replication, recombination and repair];
18-83 2.31e-19

Exonuclease VII small subunit [Replication, recombination and repair];


Pssm-ID: 441328  Cd Length: 74  Bit Score: 74.12  E-value: 2.31e-19
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 886166823 18 PVSQLGYEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVSDVLAGDEAQ 83
Cdd:COG1722   1 DKKELSFEEALAELEEIVERLESGELPLEESLALYERGVALAKRCQKKLDEAEQKVEKLLEDEDGE 66
xseB TIGR01280
exodeoxyribonuclease VII, small subunit; This protein is the small subunit for ...
 24-76 9.76e-15

exodeoxyribonuclease VII, small subunit; This protein is the small subunit for exodeoxyribonuclease VII. Exodeoxyribonuclease VII is made of a complex of four small subunits to one large subunit. The complex degrades single-stranded DNA into large acid-insoluble oligonucleotides. These nucleotides are then degraded further into acid-soluble oligonucleotides. [DNA metabolism, Degradation of DNA]


Pssm-ID: 273536  Cd Length: 54  Bit Score: 61.67  E-value: 9.76e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 886166823  24 YEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVSDV 76
Cdd:TIGR01280  2 FEEALAELEEIVEKLESGDLSLEESLKLYEEGIKLLKHCQKKLEEAEQKIEKL 54
Exonuc_VII_S pfam02609
Exonuclease VII small subunit; This family consist of exonuclease VII, small subunit EC:3.1.11. ...
 24-73 2.43e-14

Exonuclease VII small subunit; This family consist of exonuclease VII, small subunit EC:3.1.11.6 This enzyme catalyzes exonucleolytic cleavage in either 5'->3' or 3'->5' direction to yield 5'-phosphomononucleotides. This exonuclease VII enzyme is composed of one large subunit and 4 small ones.


Pssm-ID: 460618  Cd Length: 51  Bit Score: 60.86  E-value: 2.43e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 886166823  24 YEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRV 73
Cdd:pfam02609  1 FEEALAELEEIVEKLESGELSLEESLKLYEEGIKLLKFCEKKLDEAEQKI 50
PRK14067 PRK14067
exodeoxyribonuclease VII small subunit; Provisional
 23-80 9.57e-06

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 172557  Cd Length: 80  Bit Score: 39.80  E-value: 9.57e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 886166823 23 GYEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVSDVLAGD 80
Cdd:PRK14067  8 DFEQQLARLQEIVDALEGGDLPLEESVALYKEGLGLARACREQLAKARNEIRLFTEGE 65
PRK14070 PRK14070
exodeoxyribonuclease VII small subunit; Provisional
 30-85 9.64e-06

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 184486  Cd Length: 69  Bit Score: 39.62  E-value: 9.64e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 886166823 30 ELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVSDV---LAGDEAQNG 85
Cdd:PRK14070  3 ELEEIVNRLENEDLPLEESIKLFERGVELYRKCKEILQQNRLKIIDVmkeLEGEIDASG 61
PRK14064 PRK14064
exodeoxyribonuclease VII small subunit; Provisional
 24-81 1.72e-05

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 172554  Cd Length: 75  Bit Score: 39.05  E-value: 1.72e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 886166823 24 YEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVSDVL--AGDE 81
Cdd:PRK14064  8 FEEAIAELETIVEALENGSASLEDSLDMYQKGIELTKLCQDKLQSAEKRMAKVVtdAGEE 67
PRK14069 PRK14069
exodeoxyribonuclease VII small subunit; Provisional
 20-83 6.60e-05

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 172559  Cd Length: 95  Bit Score: 38.08  E-value: 6.60e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 886166823 20 SQLGYEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVsDVLAGDEAQ 83
Cdd:PRK14069  6 SKISFEDALRELEQIAEKLERQDFSLEESLKAYERGMELKKICSGILDDAEGKI-EALTKDESG 68
PRK14066 PRK14066
exodeoxyribonuclease VII small subunit; Provisional
 24-77 1.07e-04

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 172556  Cd Length: 75  Bit Score: 36.74  E-value: 1.07e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 886166823 24 YEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVSDVL 77
Cdd:PRK14066  6 FETALKKLEEVVKKLEGGELSLDDSLKAFEEGVKHAAFCSKKLDEAERRVEVLL 59
PRK14068 PRK14068
exodeoxyribonuclease VII small subunit; Provisional
 21-85 7.27e-04

exodeoxyribonuclease VII small subunit; Provisional


Pssm-ID: 184485  Cd Length: 76  Bit Score: 34.85  E-value: 7.27e-04
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 886166823 21 QLGYEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVSDvLAGDEAQNG 85
Cdd:PRK14068  5 TQSFEEMMQELEQIVQKLDNETVSLEESLDLYQRGMKLSAACDTTLKNAEKKVND-LIKEEAEDV 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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