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Conserved domains on  [gi|893364466|emb|CNJ10425|]
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23S rRNA pseudouridylate synthase B [Yersinia intermedia]

Protein Classification

23S rRNA pseudouridine(2605) synthase RluB( domain architecture ID 11484875)

23S rRNA pseudouridine(2605) synthase RluB catalyzes the isomerization of specific uridines in an RNA molecule to pseudouridines

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10700 PRK10700
23S rRNA pseudouridine(2605) synthase RluB;
26-314 0e+00

23S rRNA pseudouridine(2605) synthase RluB;


:

Pssm-ID: 182659 [Multi-domain]  Cd Length: 289  Bit Score: 579.41  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  26 VGEKLQKILARAGHGSRREIETIIQQGRVSVDGKISTLGDRVEVTQATKIRLDGHLLSIKESEEAVCRVLAYYKPEGELC 105
Cdd:PRK10700   1 MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIATLGDRVEVTPGLKIRIDGHLISVKESAEQICRVLAYYKPEGELC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 106 TRNDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLSRGV 185
Cdd:PRK10700  81 TRNDPEGRPTVFDRLPKLRGARWIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRQLSRGV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 186 QLDDGPAAFRTISFQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLPKGLPRGGWTELDLKATNYL 265
Cdd:PRK10700 161 QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIPLPKGLPRGGWTELDLAQTNYL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 893364466 266 RELVELNSETVSKLPVEKDRRRVKANQIRRAVKRHTEVAGRQVAGRQGS 314
Cdd:PRK10700 241 RELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHSQVSGGRRSGGRNN 289
 
Name Accession Description Interval E-value
PRK10700 PRK10700
23S rRNA pseudouridine(2605) synthase RluB;
26-314 0e+00

23S rRNA pseudouridine(2605) synthase RluB;


Pssm-ID: 182659 [Multi-domain]  Cd Length: 289  Bit Score: 579.41  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  26 VGEKLQKILARAGHGSRREIETIIQQGRVSVDGKISTLGDRVEVTQATKIRLDGHLLSIKESEEAVCRVLAYYKPEGELC 105
Cdd:PRK10700   1 MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIATLGDRVEVTPGLKIRIDGHLISVKESAEQICRVLAYYKPEGELC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 106 TRNDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLSRGV 185
Cdd:PRK10700  81 TRNDPEGRPTVFDRLPKLRGARWIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRQLSRGV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 186 QLDDGPAAFRTISFQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLPKGLPRGGWTELDLKATNYL 265
Cdd:PRK10700 161 QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIPLPKGLPRGGWTELDLAQTNYL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 893364466 266 RELVELNSETVSKLPVEKDRRRVKANQIRRAVKRHTEVAGRQVAGRQGS 314
Cdd:PRK10700 241 RELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHSQVSGGRRSGGRNN 289
RsuA COG1187
Pseudouridylate synthase RsuA, specific for 16S rRNA U516 and 23S rRNA U2605 [Translation, ...
 27-258 7.40e-110

Pseudouridylate synthase RsuA, specific for 16S rRNA U516 and 23S rRNA U2605 [Translation, ribosomal structure and biogenesis]; Pseudouridylate synthase RsuA, specific for 16S rRNA U516 and 23S rRNA U2605 is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 440800 [Multi-domain]  Cd Length: 226  Bit Score: 319.29  E-value: 7.40e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  27 GEKLQKILARAGHGSRREIETIIQQGRVSVDGKI-STLGDRVEVTQatKIRLDGHLLSIKESeeavCRVLAYYKPEGELC 105
Cdd:COG1187    2 GMRLQKFLANAGVGSRREAEELIEAGRVTVNGKVvTELGTKVDPGD--EVTVDGKPLKLPEE----PVYLLLNKPAGVVS 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 106 TRNDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLSRGV 185
Cdd:COG1187   76 TTKDPEGRPTVFDLLPEARKERLFPVGRLDKDTEGLLLLTNDGELAHRLTHPKYGVEKEYLVRVDGPVTEEDLERLREGV 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 893364466 186 QLDDGPAAFRTISFQGGEGiNQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLpKGLPRGGWTELD 258
Cdd:COG1187  156 ELEDGPTKPAKVEILSGEA-NTWLRITLTEGRNRQVRRMFEAVGLPVVRLKRVRIGPLTL-GDLPPGEWRELT 226
PseudoU_synth_RluB cd02556
Pseudouridine synthase, Escherichia coli RluB like; This group is comprised of bacterial and ...
 93-258 6.40e-101

Pseudouridine synthase, Escherichia coli RluB like; This group is comprised of bacterial and eukaryotic proteins similar to E. coli RluB. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. E.coli RluB makes psi2605 in 23S RNA. psi2605 has been detected in eubacteria but, not in eukarya and archea despite the presence of a precursor U at that site.


Pssm-ID: 211330 [Multi-domain]  Cd Length: 167  Bit Score: 294.22  E-value: 6.40e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  93 RVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQ 172
Cdd:cd02556    1 RVLIYHKPEGLICTRKDPKGRPTVFDLLPKLGIPRWISVGRLDLNTEGLLLFTNDGELANRLMHPSNEIEREYAVRVFGQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 173 IDDEKIKQLSRGVQLDDGPAAFRTISFQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLPKGLPRG 252
Cdd:cd02556   81 VTDEQLKSLKKGVELEDGFAGFKSIQLEGGEGKNSWYRVTLREGRNREVRRLWEAFGLQVSRLIRIRYGPIFLPGNLKRG 160


                 ....*.
gi 893364466 253 GWTELD 258
Cdd:cd02556  161 QWEELP 166
TIGR00093 TIGR00093
pseudouridine synthase; This model identifies panels of pseudouridine synthase enzymes that ...
 131-259 4.11e-62

pseudouridine synthase; This model identifies panels of pseudouridine synthase enzymes that RNA modifications involved in maturing the protein translation apparatus. Counts per genome vary: two in Staphylococcus aureus, three in Pseudomonas putida, four in E. coli, etc. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 272902  Cd Length: 128  Bit Score: 194.08  E-value: 4.11e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  131 VGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLSRGVQLDDGPAAFRTISFQGGEGINQWYN 210
Cdd:TIGR00093   1 VGRLDRDSEGLLLLTNDGELVHRLTHPGHHHEKEYLVTVEGPVTDEDLEALRKGVQLEDGKTKPAKLKVITEPGFPTWLR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 893364466  211 VTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLpKGLPRGGWTELDL 259
Cdd:TIGR00093  81 VTLSEGRNRQVRRMFAAVGFPVLRLHRVRIGDVSL-NGLPPGEWRPLTL 128
PseudoU_synth_2 pfam00849
RNA pseudouridylate synthase; Members of this family are involved in modifying bases in RNA ...
 94-223 5.38e-21

RNA pseudouridylate synthase; Members of this family are involved in modifying bases in RNA molecules. They carry out the conversion of uracil bases to pseudouridine. This family includes RluD, a pseudouridylate synthase that converts specific uracils to pseudouridine in 23S rRNA. RluA from E. coli converts bases in both rRNA and tRNA.


Pssm-ID: 459961 [Multi-domain]  Cd Length: 151  Bit Score: 87.85  E-value: 5.38e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466   94 VLAYYKPEGELCTRNDPEG---RPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMH--PSREVEREYAVR 168
Cdd:pfam00849   1 YIVVNKPAGVPVHPTDSLTkllSLLALLLRRELGVKRLYPVHRLDKNTSGLLLLAKDGEAANKLNKlfPERKIEKEYLAL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 893364466  169 VFG----------QIDDEKIKQLSRGVQLDDGPAA---FRTISfQGGEGINQWYNVTLTEGRNREVRR 223
Cdd:pfam00849  81 VDKpeeeegtiksPIKKEKNKSPFRKEEELGGKKAvthLKVLK-SGSKGDYSLLELELVTGRKHQIRA 147
S4 smart00363
S4 RNA-binding domain;
30-69 1.94e-04

S4 RNA-binding domain;


Pssm-ID: 214638 [Multi-domain]  Cd Length: 60  Bit Score: 38.73  E-value: 1.94e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 893364466    30 LQKILARAG-HGSRREIETIIQQGRVSVDGKIST-------LGDRVEV 69
Cdd:smart00363   3 LDKFLARLGlAPSRSQARRLIEQGRVKVNGKKVTkpsyivkPGDVISV 50
 
Name Accession Description Interval E-value
PRK10700 PRK10700
23S rRNA pseudouridine(2605) synthase RluB;
26-314 0e+00

23S rRNA pseudouridine(2605) synthase RluB;


Pssm-ID: 182659 [Multi-domain]  Cd Length: 289  Bit Score: 579.41  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  26 VGEKLQKILARAGHGSRREIETIIQQGRVSVDGKISTLGDRVEVTQATKIRLDGHLLSIKESEEAVCRVLAYYKPEGELC 105
Cdd:PRK10700   1 MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIATLGDRVEVTPGLKIRIDGHLISVKESAEQICRVLAYYKPEGELC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 106 TRNDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLSRGV 185
Cdd:PRK10700  81 TRNDPEGRPTVFDRLPKLRGARWIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRQLSRGV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 186 QLDDGPAAFRTISFQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLPKGLPRGGWTELDLKATNYL 265
Cdd:PRK10700 161 QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIPLPKGLPRGGWTELDLAQTNYL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 893364466 266 RELVELNSETVSKLPVEKDRRRVKANQIRRAVKRHTEVAGRQVAGRQGS 314
Cdd:PRK10700 241 RELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHSQVSGGRRSGGRNN 289
RsuA COG1187
Pseudouridylate synthase RsuA, specific for 16S rRNA U516 and 23S rRNA U2605 [Translation, ...
 27-258 7.40e-110

Pseudouridylate synthase RsuA, specific for 16S rRNA U516 and 23S rRNA U2605 [Translation, ribosomal structure and biogenesis]; Pseudouridylate synthase RsuA, specific for 16S rRNA U516 and 23S rRNA U2605 is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 440800 [Multi-domain]  Cd Length: 226  Bit Score: 319.29  E-value: 7.40e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  27 GEKLQKILARAGHGSRREIETIIQQGRVSVDGKI-STLGDRVEVTQatKIRLDGHLLSIKESeeavCRVLAYYKPEGELC 105
Cdd:COG1187    2 GMRLQKFLANAGVGSRREAEELIEAGRVTVNGKVvTELGTKVDPGD--EVTVDGKPLKLPEE----PVYLLLNKPAGVVS 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 106 TRNDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLSRGV 185
Cdd:COG1187   76 TTKDPEGRPTVFDLLPEARKERLFPVGRLDKDTEGLLLLTNDGELAHRLTHPKYGVEKEYLVRVDGPVTEEDLERLREGV 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 893364466 186 QLDDGPAAFRTISFQGGEGiNQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLpKGLPRGGWTELD 258
Cdd:COG1187  156 ELEDGPTKPAKVEILSGEA-NTWLRITLTEGRNRQVRRMFEAVGLPVVRLKRVRIGPLTL-GDLPPGEWRELT 226
PseudoU_synth_RluB cd02556
Pseudouridine synthase, Escherichia coli RluB like; This group is comprised of bacterial and ...
 93-258 6.40e-101

Pseudouridine synthase, Escherichia coli RluB like; This group is comprised of bacterial and eukaryotic proteins similar to E. coli RluB. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. E.coli RluB makes psi2605 in 23S RNA. psi2605 has been detected in eubacteria but, not in eukarya and archea despite the presence of a precursor U at that site.


Pssm-ID: 211330 [Multi-domain]  Cd Length: 167  Bit Score: 294.22  E-value: 6.40e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  93 RVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQ 172
Cdd:cd02556    1 RVLIYHKPEGLICTRKDPKGRPTVFDLLPKLGIPRWISVGRLDLNTEGLLLFTNDGELANRLMHPSNEIEREYAVRVFGQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 173 IDDEKIKQLSRGVQLDDGPAAFRTISFQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLPKGLPRG 252
Cdd:cd02556   81 VTDEQLKSLKKGVELEDGFAGFKSIQLEGGEGKNSWYRVTLREGRNREVRRLWEAFGLQVSRLIRIRYGPIFLPGNLKRG 160


                 ....*.
gi 893364466 253 GWTELD 258
Cdd:cd02556  161 QWEELP 166
TIGR00093 TIGR00093
pseudouridine synthase; This model identifies panels of pseudouridine synthase enzymes that ...
 131-259 4.11e-62

pseudouridine synthase; This model identifies panels of pseudouridine synthase enzymes that RNA modifications involved in maturing the protein translation apparatus. Counts per genome vary: two in Staphylococcus aureus, three in Pseudomonas putida, four in E. coli, etc. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 272902  Cd Length: 128  Bit Score: 194.08  E-value: 4.11e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  131 VGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLSRGVQLDDGPAAFRTISFQGGEGINQWYN 210
Cdd:TIGR00093   1 VGRLDRDSEGLLLLTNDGELVHRLTHPGHHHEKEYLVTVEGPVTDEDLEALRKGVQLEDGKTKPAKLKVITEPGFPTWLR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 893364466  211 VTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLpKGLPRGGWTELDL 259
Cdd:TIGR00093  81 VTLSEGRNRQVRRMFAAVGFPVLRLHRVRIGDVSL-NGLPPGEWRPLTL 128
PseudoU_synth_RsuA_like cd02870
Pseudouridine synthases, RsuA subfamily; Pseudouridine synthases are responsible for the ...
 94-240 1.20e-61

Pseudouridine synthases, RsuA subfamily; Pseudouridine synthases are responsible for the synthesis of pseudouridine from uracil in ribosomal RNA. The RsuA subfamily includes Pseudouridine Synthase similar to Ribosomal small subunit pseudouridine 516 synthase. Most of the proteins in this family are bacterial proteins.


Pssm-ID: 211347 [Multi-domain]  Cd Length: 146  Bit Score: 193.48  E-value: 1.20e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  94 VLAYYKPEGELCTRNDPEGRPTVFDrLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQI 173
Cdd:cd02870    1 YLLLNKPRGVVSTVRDPEGRPTVLD-LLKDVGERLFPVGRLDYDTEGLLLLTNDGELANRLTHPRYGVEKTYLVKVRGVP 79

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 893364466 174 DDEKIKQLSRGVQLDDGPAAFRTISFQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRY 240
Cdd:cd02870   80 SEEELRRLRAGVELDDGKTAPAKVKVLSRDPKNTLLEVTLHEGRNRQVRRMFEAVGHPVLRLKRVRI 146
PseudoU_synth_Rsu_Rlu_like cd02550
Pseudouridine synthase, Rsu/Rlu family; This group is comprised of eukaryotic, bacterial and ...
 94-240 3.49e-54

Pseudouridine synthase, Rsu/Rlu family; This group is comprised of eukaryotic, bacterial and archeal proteins similar to eight site specific Escherichia coli pseudouridine synthases: RsuA, RluA, RluB, RluC, RluD, RluE, RluF and TruA. Pseudouridine synthases catalyze the isomerization of specific uridines in a n RNA molecule to pseudouridines (5-ribosyluracil, psi) requiring no cofactors. E. coli RluC for example makes psi955, 2504 and 2580 in 23S RNA. Some psi sites such as psi1917 in 23S RNA made by RluD are universally conserved. Other psi sites occur in a more restricted fashion, for example psi2819 in 21S mitochondrial ribosomal RNA made by S. cerevisiae Pus5p is only found in mitochondrial large subunit rRNAs from some other species and in gram negative bacteria. The E. coli counterpart of this psi residue is psi2580 in 23S rRNA. psi2604in 23S RNA made by RluF has only been detected in E.coli.


Pssm-ID: 211325 [Multi-domain]  Cd Length: 154  Bit Score: 174.87  E-value: 3.49e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  94 VLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQI 173
Cdd:cd02550    1 ILVLNKPSGLVCHPTDRDRDPTVVVRLDKLHGPRVHAAGRLDKDTSGLLLLTNDGRLQRRLTEPRREIEKEYLVTVRGEL 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 893364466 174 DDEKIKQLS-------RGVQLDDGPAAFRTISFQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRY 240
Cdd:cd02550   81 DEEGIEDLAtvrrgrlSGLVDEGVPLAVTKVRVIGEHGGTGRLRLTLKTGRTHQIRRHCAAVGFPVLRLHRVRI 154
PseudoU_synth_RsuA cd02553
Pseudouridine synthase, Escherichia coli RsuA like; This group is comprised of eukaryotic and ...
 96-257 5.56e-40

Pseudouridine synthase, Escherichia coli RsuA like; This group is comprised of eukaryotic and bacterial proteins similar to Escherichia coli RsuA. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. E.coli RsuA makes psi516 in 16S RNA. Psi at this position is not generally conserved in other organisms.


Pssm-ID: 211327 [Multi-domain]  Cd Length: 167  Bit Score: 138.42  E-value: 5.56e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  96 AYY---KPEGELCTRNDPEGrPTVFDRLPKLRGSRWV-AVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFG 171
Cdd:cd02553    1 VYLmlnKPAGVVCATKDPHH-PTVIDLLPEPDRRRDLfPVGRLDKDTTGLLLLTNDGQLAHRLTSPKKHVPKTYEVTLAG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 172 QIDDEKIKQLSRGVQLDDG----PAAFRTISfqggegiNQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLPK 247
Cdd:cd02553   80 PLTEDDIEAFAEGVLLHDGyptkPAKLEILS-------PTTVRLTITEGKYHQVKRMFAAVGNKVVALHRIRIGGLELDD 152

                        170
                 ....*....|
gi 893364466 248 GLPRGGWTEL 257
Cdd:cd02553  153 DLAPGEWRPL 162
PRK10475 PRK10475
23S rRNA pseudouridine(2604) synthase RluF;
29-322 2.88e-30

23S rRNA pseudouridine(2604) synthase RluF;


Pssm-ID: 236698 [Multi-domain]  Cd Length: 290  Bit Score: 116.37  E-value: 2.88e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  29 KLQKILARAGHGSRREIETIIQQGRVSVDGKISTLGDRVEVtqATKIRLDGHLLSIKESEEAVcrVLAYYKPEGELCTRN 108
Cdd:PRK10475   8 RLNKYISESGICSRREADRYIEQGNVFINGKRATIGDQVKA--GDVVKVNGQLIEPREAEDLV--LIALNKPVGIVSTTE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 109 DPEgRPTVFDRLPklRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLSRGVQL- 187
Cdd:PRK10475  84 DGE-RDNIVDFVN--HSKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPIl 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 188 ----------DDGPAAFRtisfqggeginqwynVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLpKGLPRGGWTEL 257
Cdd:PRK10475 161 gtvtkkckvkKEAPFVFR---------------ITLVQGLNRQIRRMCEHFGYEVTKLERTRIMNVSL-SGIPLGEWRDL 224

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 893364466 258 DLKATNYLRELVElNSETVSKlPVEKDRRRVKAnqIRRAVKRHTEVAGRqvAGRQGSARKSSTRQ 322
Cdd:PRK10475 225 TDDELIDLFKLIE-NSSSEAK-PKAKAKPKTAG--IKRPVVKMEKTAEK--GGRPASNGKRFTSP 283
PseudoU_synth_RluF cd02554
Pseudouridine synthase, Escherichia coli RluF like; This group is comprised of bacterial ...
 95-257 7.15e-28

Pseudouridine synthase, Escherichia coli RluF like; This group is comprised of bacterial proteins similar to Escherichia coli RluF. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. E.coli RluF makes psi2604 in 23S RNA. psi2604 has only been detected in E. coli. It is absent from other eubacteria despite a precursor U at that site and from eukarya and archea which lack a precursor U at that site.


Pssm-ID: 211328 [Multi-domain]  Cd Length: 164  Bit Score: 106.62  E-value: 7.15e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  95 LAYYKPEGELCTRNDPEgRPTVFDRLPKlrGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQID 174
Cdd:cd02554    3 IAYNKPVGIDCTLERAD-EDNIIDFVNP--PPRIFPIGRLDKDSEGLILLTNDGDLVNKILHADNNHEKEYLVTVNKPIT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 175 DEKIKQLSRGVQLDDG---PAAFRTISFQGgeginqwYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLpKGLPR 251
Cdd:cd02554   80 DEFIEGMSNGVVILGTvtkPCKVERLAKDK-------FRIVLTQGLNRQIRRMCEALGYRVTDLKRVRIMNIEL-GDLAP 151


                 ....*.
gi 893364466 252 GGWTEL 257
Cdd:cd02554  152 GEWRPL 157
PseudoU_synth_RluE cd02566
Pseudouridine synthase, Escherichia coli RluE; This group is comprised of bacterial proteins ...
 94-245 4.79e-27

Pseudouridine synthase, Escherichia coli RluE; This group is comprised of bacterial proteins similar to E. coli RluE. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. Escherichia coli RluE makes psi2457 in 23S RNA. psi2457 is not universally conserved.


Pssm-ID: 211334 [Multi-domain]  Cd Length: 168  Bit Score: 104.39  E-value: 4.79e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  94 VLAYYKPEGELCT-RNDPEGRPTVFDRL--PKLRgsrwvAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVF 170
Cdd:cd02566    1 LILFNKPYGVLSQfTDESEKHKTLKDYIddPGVY-----AAGRLDRDSEGLLLLTDDGRLQHRITDPSFKHPKTYYVQVE 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 171 GQIDDEKIKQLSRGVQLDDGPA----AFRT------------ISFQgGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSR 234
Cdd:cd02566   76 GVPTEDALEQLRNGVELGDGLTlpakVEKVdeppwlwereppIRFR-KNIPTSWIEITICEGKNRQVRRMTAAVGFPTLR 154

                        170
                 ....*....|.
gi 893364466 235 LIRVRYGDINL 245
Cdd:cd02566  155 LIRVSIGDIGL 165
PRK10839 PRK10839
16S rRNA pseudouridine(516) synthase RsuA;
29-257 1.53e-22

16S rRNA pseudouridine(516) synthase RsuA;


Pssm-ID: 236774 [Multi-domain]  Cd Length: 232  Bit Score: 94.40  E-value: 1.53e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  29 KLQKILARAGHGSRREIETIIQQGRVSVDGKISTLGdRVEVTQATKIRLDGHLLSIKESEeavcRVLAYYKPEGELCTRN 108
Cdd:PRK10839   2 RLDKFISQQLGVSRAIAGRELRANRVTVDGEIVKNG-AFKLLPEHDVAYDGNPLAQQHGP----RYFMLNKPQGYVCSTD 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 109 DPEgRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLSRGVQLD 188
Cdd:PRK10839  77 DPD-HPTVLYFLDEPVAYKLHAAGRLDIDTTGLVLMTDDGQWSHRITSPRHHCEKTYLVTLESPVADDTAEQFAKGVQLH 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 893364466 189 D-----GPAAFRTISfqggegiNQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLPKGLPRGGWTEL 257
Cdd:PRK10839 156 NekdltKPAVLEVIT-------PTQVRLTISEGRYHQVKRMFAAVGNHVVELHRERIGAITLDADLAPGEYRPL 222
PseudoU_synth_2 pfam00849
RNA pseudouridylate synthase; Members of this family are involved in modifying bases in RNA ...
 94-223 5.38e-21

RNA pseudouridylate synthase; Members of this family are involved in modifying bases in RNA molecules. They carry out the conversion of uracil bases to pseudouridine. This family includes RluD, a pseudouridylate synthase that converts specific uracils to pseudouridine in 23S rRNA. RluA from E. coli converts bases in both rRNA and tRNA.


Pssm-ID: 459961 [Multi-domain]  Cd Length: 151  Bit Score: 87.85  E-value: 5.38e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466   94 VLAYYKPEGELCTRNDPEG---RPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMH--PSREVEREYAVR 168
Cdd:pfam00849   1 YIVVNKPAGVPVHPTDSLTkllSLLALLLRRELGVKRLYPVHRLDKNTSGLLLLAKDGEAANKLNKlfPERKIEKEYLAL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 893364466  169 VFG----------QIDDEKIKQLSRGVQLDDGPAA---FRTISfQGGEGINQWYNVTLTEGRNREVRR 223
Cdd:pfam00849  81 VDKpeeeegtiksPIKKEKNKSPFRKEEELGGKKAvthLKVLK-SGSKGDYSLLELELVTGRKHQIRA 147
PRK11394 PRK11394
23S rRNA pseudouridine(2457) synthase RluE;
76-256 3.72e-18

23S rRNA pseudouridine(2457) synthase RluE;


Pssm-ID: 183115  Cd Length: 217  Bit Score: 81.71  E-value: 3.72e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  76 RLDGHLLSIKESEEAVCRVLAYYKPEGELCTRNDPEGRPTVFDRLPkLRGSrwVAVGRLDVNTSGLLLFTTDGELANRLM 155
Cdd:PRK11394  23 RFSSQRSTRRKPENQPTRVILFNKPYDVLPQFTDEAGRKTLKEFIP-VQGV--YAAGRLDRDSEGLLVLTNNGALQARLT 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 156 HPSREVEREYAVRVFGQIDDEKIKQLSRGVQLDDGPAAF--------------RTISFQGGEGI-NQWYNVTLTEGRNRE 220
Cdd:PRK11394 100 QPGKRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPagaelvdepawlwpRNPPIRERKSIpTSWLKITLYEGRNRQ 179

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 893364466 221 VRRLWEAVGVQVSRLIRVRYGDINLpKGLPRGGWTE 256
Cdd:PRK11394 180 VRRMTAHVGFPTLRLIRYAMGDYSL-DNLANGEWRE 214
PSSA_1 cd02555
Pseudouridine synthase, a subgroup of the RsuA family; This group is comprised of bacterial ...
 98-254 4.71e-17

Pseudouridine synthase, a subgroup of the RsuA family; This group is comprised of bacterial proteins assigned to the RsuA family of pseudouridine synthases. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. The TruA family is comprised of proteins related to Escherichia coli RsuA.


Pssm-ID: 211329 [Multi-domain]  Cd Length: 177  Bit Score: 77.83  E-value: 4.71e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  98 YKPEGELCTRNDP---EGRPTVFDRLPK--LRG--SRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVF 170
Cdd:cd02555   10 HKPAGMVSEQALAllgPGQRSAADRSGRrpLKGhfARLAPIGPLDKDASGLLVFSQDGRVLRKLIGDASRLEQEYLVEVR 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466 171 GQIDDEKIKQLSRGVQLDDGPAAFRTISFQGGEGInqwyNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDINLPKgLP 250
Cdd:cd02555   90 GELTAGGLERLNHGLTYDGRELPPAKVSWQNEQRL----RFALKEPQPGQIRRMCESVGLEVVALRRIRIGRVSLGK-LP 164


                 ....
gi 893364466 251 RGGW 254
Cdd:cd02555  165 LGQW 168
rluA_subfam TIGR00005
pseudouridine synthase, RluA family; In E. coli, RluD (SfhB) modifies uridine to pseudouridine ...
 27-177 5.36e-06

pseudouridine synthase, RluA family; In E. coli, RluD (SfhB) modifies uridine to pseudouridine at 23S RNA U1911, 1915, and 1917, RluC modifies 955, 2504 and 2580, and RluA modifies U746 and tRNA U32. An additional homolog from E. coli outside this family, TruC (SP|Q46918), modifies uracil-65 in transfer RNAs to pseudouridine. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 161659 [Multi-domain]  Cd Length: 299  Bit Score: 47.32  E-value: 5.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466   27 GEKLQKILARA-GHGSRREIETIIQQGRVSVDGKI----STL---GDRVEVTQATKIRLDGHLLSIK-----ESEEavcr 93
Cdd:TIGR00005   5 GQRLDDFLASLlPDLSRSRIQKLIENGQVKVNGKVtanpKLKvkdGDRITVRVPEEEEHEVPPQDIPldilfEDED---- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466   94 VLAYYKPEGELCtrnDPEGR---PTVFDRLPKLRGSRWVA-----VGRLDVNTSGLLLF--TTDG--ELANRLMhpSREV 161
Cdd:TIGR00005  81 IIVINKPSGLVV---HPGGGnpfGTVLNALLAHCPPIAGVervgiVHRLDRDTSGLMVVakTPLAlrELQRQLK--NRTV 155

                         170
                  ....*....|....*.
gi 893364466  162 EREYAVRVFGQIDDEK 177
Cdd:TIGR00005 156 TKEYVALVHGQFDSGG 171
S4 cd00165
S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, ...
 30-89 1.51e-05

S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized functional similarity between these three protein classes.


Pssm-ID: 238095 [Multi-domain]  Cd Length: 70  Bit Score: 42.24  E-value: 1.51e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 893364466  30 LQKILARAG-HGSRREIETIIQQGRVSVDGKIST-LGDRVEVTQatKIRLDGHLLSIKESEE 89
Cdd:cd00165    3 LDKILARLGlAPSRSEARQLIKHGHVLVNGKVVTkPSYKVKPGD--VIEVDGKSIEEDIVYE 62
PseudoU_synth_RluA_like cd02869
Pseudouridine synthase, RluA family; This group is comprised of eukaryotic, bacterial and ...
 94-208 4.51e-05

Pseudouridine synthase, RluA family; This group is comprised of eukaryotic, bacterial and archeal proteins similar to eight site specific Escherichia coli pseudouridine synthases: RsuA, RluA, RluB, RluC, RluD, RluE, RluF and TruA. Pseudouridine synthases catalyze the isomerization of specific uridines in a n RNA molecule to pseudouridines (5-ribosyluracil, psi) requiring no cofactors. E. coli RluC for example makes psi955, 2504 and 2580 in 23S RNA. Some psi sites such as psi1917 in 23S RNA made by RluD are universally conserved. Other psi sites occur in a more restricted fashion, for example psi2819 in 21S mitochondrial ribosomal RNA made by S. cerevisiae Pus5p is only found in mitochondrial large subunit rRNAs from some other species and in gram negative bacteria. The E. coli counterpart of this psi residue is psi2580 in 23S rRNA. psi2604in 23S RNA made by RluF has only been detected in E.coli.


Pssm-ID: 211346 [Multi-domain]  Cd Length: 185  Bit Score: 43.48  E-value: 4.51e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  94 VLAYYKPEGELCTRNDPEGRPTVFDRLPKLR-----GSRWVAVGRLDVNTSGLLLFTTDGELANRL--MHPSREVEREYA 166
Cdd:cd02869    1 LLVVNKPAGLPVHPGPGHLTGTLVNALLKLLlllgeEFRPGLVHRLDKDTSGLLLVAKNKKAAAKLskQFKERKVKKTYL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 893364466 167 VRVFGQIDDEKIKQLSRGVQLDDGPAAFRTISFQGGEGINQW 208
Cdd:cd02869   81 ALVDGKPPEDEGTIDAPLGRKKRKKRARVVVSEDGKPAITHY 122
PseudoU_synth_ScRIB2 cd02557
Pseudouridine synthases similar to Saccharomyces cerevisiae RIB2; Pseudouridine synthase, ...
 133-178 4.60e-05

Pseudouridine synthases similar to Saccharomyces cerevisiae RIB2; Pseudouridine synthase, Saccharomyces cerevisiae RIB2_like. This group is comprised of eukaryotic and bacterial proteins similar to Saccharomyces cerevisiae RIB2, S. cerevisiae Pus6p and human hRPUDSD2. S. cerevisiae RIB2 displays two distinct catalytic activities. The N-terminal domain of RIB2 is RNA:psi-synthase which makes psi32 on cytoplasmic tRNAs. Psi32 is highly phylogenetically conserved. The C-terminal domain of RIB2 has a DRAP deaminase activity which catalyses the formation of 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate from 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate during riboflavin biosynthesis. S. cerevisiae Pus6p makes the psi31 of cytoplasmic and mitochondrial tRNAs.


Pssm-ID: 211331 [Multi-domain]  Cd Length: 213  Bit Score: 43.77  E-value: 4.60e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 893364466 133 RLDVNTSGLLLFTTDGELANRL--MHPSREVEREYAVRVFGQIDDEKI 178
Cdd:cd02557   65 RLDRLTSGLLLFAKTSQTASRLqqQIRSREVKKEYLARVKGEFPDGEV 112
S4 pfam01479
S4 domain; The S4 domain is a small domain consisting of 60-65 amino acid residues that was ...
 28-69 1.58e-04

S4 domain; The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation. The S4 domain probably mediates binding to RNA.


Pssm-ID: 396182 [Multi-domain]  Cd Length: 48  Bit Score: 38.63  E-value: 1.58e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 893364466   28 EKLQKILARAGHG-SRREIETIIQQGRVSVDGKIST-LGDRVEV 69
Cdd:pfam01479   1 RRLDKVLARLGLAsSRSQARQLIEHGRVLVNGKVVKdPSYRVKP 44
S4 smart00363
S4 RNA-binding domain;
30-69 1.94e-04

S4 RNA-binding domain;


Pssm-ID: 214638 [Multi-domain]  Cd Length: 60  Bit Score: 38.73  E-value: 1.94e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 893364466    30 LQKILARAG-HGSRREIETIIQQGRVSVDGKIST-------LGDRVEV 69
Cdd:smart00363   3 LDKFLARLGlAPSRSQARRLIEQGRVKVNGKKVTkpsyivkPGDVISV 50
RluA COG0564
Pseudouridine synthase RluA, 23S rRNA- or tRNA-specific [Translation, ribosomal structure and ...
 94-177 4.14e-03

Pseudouridine synthase RluA, 23S rRNA- or tRNA-specific [Translation, ribosomal structure and biogenesis]; Pseudouridine synthase RluA, 23S rRNA- or tRNA-specific is part of the Pathway/BioSystem: 23S rRNA modification


Pssm-ID: 440330 [Multi-domain]  Cd Length: 218  Bit Score: 38.19  E-value: 4.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 893364466  94 VLAYYKPEGELCTRNDPEGRPTVFDRL----PKLRGSRWV-AVGRLDVNTSGLLLFTTDGELANRL--MHPSREVEREYA 166
Cdd:COG0564    8 LLVVNKPAGLVVHPGSGGDDGTLVNALrahlGELSGVPRPgLVHRLDRDTSGLLLVAKTRKAARRLseQFREREVEKRYL 87

                         90
                 ....*....|.
gi 893364466 167 VRVFGQIDDEK 177
Cdd:COG0564   88 ALVEGKPKEDE 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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