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Conserved domains on  [gi|907808748|emb|CTC93405|]
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putative exported protein [Streptococcus pneumoniae]

Protein Classification

LysM peptidoglycan-binding domain-containing protein( domain architecture ID 10061503)

LysM peptidoglycan-binding domain-containing protein may bind N-acetylglucosamine in carbohydrates such as chitin, chitio-oligosaccharides and peptidoglycan

CATH:  3.10.350.10
Gene Ontology:  GO:0097367
PubMed:  18430080|24652063
SCOP:  4000905

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LysM cd00118
Lysin Motif is a small domain involved in binding peptidoglycan; LysM, a small globular domain ...
 47-90 8.79e-10

Lysin Motif is a small domain involved in binding peptidoglycan; LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.


:

Pssm-ID: 212030 [Multi-domain]  Cd Length: 45  Bit Score: 53.64  E-value: 8.79e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 907808748  47 TSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLT 90
Cdd:cd00118    1 KTYTVKPGDTLWSIAKKYGVTVEELAAANPLINPDCIYPGQKLK 44
rne super family cl35953
ribonuclease E; Reviewed
 85-240 1.21e-08

ribonuclease E; Reviewed


The actual alignment was detected with superfamily member PRK10811:

Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 56.97  E-value: 1.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748   85 PETVLTTTVNEAEEVTEVEIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTVIASE 164
Cdd:PRK10811  880 EPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADI 959

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 907808748  165 EVAPSTGTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTttssEAKEVASSNGATAAVSTYQPE 240
Cdd:PRK10811  960 EEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEAT----VEHNHATAPMTRAPAPEYVPE 1031
 
Name Accession Description Interval E-value
LysM cd00118
Lysin Motif is a small domain involved in binding peptidoglycan; LysM, a small globular domain ...
 47-90 8.79e-10

Lysin Motif is a small domain involved in binding peptidoglycan; LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.


Pssm-ID: 212030 [Multi-domain]  Cd Length: 45  Bit Score: 53.64  E-value: 8.79e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 907808748  47 TSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLT 90
Cdd:cd00118    1 KTYTVKPGDTLWSIAKKYGVTVEELAAANPLINPDCIYPGQKLK 44
rne PRK10811
ribonuclease E; Reviewed
 85-240 1.21e-08

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 56.97  E-value: 1.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748   85 PETVLTTTVNEAEEVTEVEIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTVIASE 164
Cdd:PRK10811  880 EPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADI 959

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 907808748  165 EVAPSTGTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTttssEAKEVASSNGATAAVSTYQPE 240
Cdd:PRK10811  960 EEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEAT----VEHNHATAPMTRAPAPEYVPE 1031
LysM smart00257
Lysin motif;
49-90 2.11e-08

Lysin motif;


Pssm-ID: 197609 [Multi-domain]  Cd Length: 44  Bit Score: 49.75  E-value: 2.11e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 907808748    49 YTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLT 90
Cdd:smart00257   2 YTVKKGDTLSSIARRYGISVSDLLELNNILDPDNLQVGQKLK 43
LysM pfam01476
LysM domain; The LysM (lysin motif) domain is about 40 residues long. It is found in a variety ...
 49-90 4.13e-08

LysM domain; The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. The structure of this domain is known.


Pssm-ID: 396179 [Multi-domain]  Cd Length: 43  Bit Score: 48.93  E-value: 4.13e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 907808748   49 YTVQYGDTLSTIAEALGVDVTVLANLNKITNmDLIFPETVLT 90
Cdd:pfam01476   1 YTVKKGDTLSSIAKRYGITVEQLAELNGLSS-PNLYVGQKLK 41
LysM COG1388
LysM repeat [Cell wall/membrane/envelope biogenesis];
41-90 3.65e-07

LysM repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440998 [Multi-domain]  Cd Length: 156  Bit Score: 49.32  E-value: 3.65e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 907808748  41 TKTDNKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNmDLIFPETVLT 90
Cdd:COG1388  104 AAAPSPVTYTVKKGDTLWSIARRYGVSVEELKRWNGLSS-DTIRPGQKLK 152
COG5373 COG5373
Uncharacterized membrane protein [Function unknown];
122-213 8.02e-04

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 444140 [Multi-domain]  Cd Length: 854  Bit Score: 41.52  E-value: 8.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748 122 LTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSE-VTKTVIASEEVAPSTGTSVPEEQTTETTRPVEEATPQETTPAEKQ 200
Cdd:COG5373   16 LVGLLGRVARLRRRVEELEAELAEAAEAASAPAEpEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEA 95

                         90
                 ....*....|...
gi 907808748 201 ETQASPQAASAVE 213
Cdd:COG5373   96 EPAAAPAAASSFE 108
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 104-277 6.57e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 38.74  E-value: 6.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748 104 IQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTVI----ASEEVAPSTGTSVPEEQT 179
Cdd:NF033609  32 LSSKEADASENSVTQSDSASNESKSNDSSSVSAAPKTDDTNVSDTKTSSNTNNGETSVaqnpAQQETTQSASTNATTEET 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748 180 TETTRPVEEATPQETTPAEKQETQA-SPQAASAVEVTTTSSEAKEVASSNG---ATAA--VSTYQPEETKIISTTYE-AP 252
Cdd:NF033609 112 PVTGEATTTATNQANTPATTQSSNTnAEELVNQTSNETTSNDTNTVSSVNSpqnSTNAenVSTTQDTSTEATPSNNEsAP 191

                        170       180
                 ....*....|....*....|....*
gi 907808748 253 AAPDYAGLAVAKSENAGLQPQTAAF 277
Cdd:NF033609 192 QSTDASNKDVVNQAVNTSAPRMRAF 216
 
Name Accession Description Interval E-value
LysM cd00118
Lysin Motif is a small domain involved in binding peptidoglycan; LysM, a small globular domain ...
 47-90 8.79e-10

Lysin Motif is a small domain involved in binding peptidoglycan; LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.


Pssm-ID: 212030 [Multi-domain]  Cd Length: 45  Bit Score: 53.64  E-value: 8.79e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 907808748  47 TSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLT 90
Cdd:cd00118    1 KTYTVKPGDTLWSIAKKYGVTVEELAAANPLINPDCIYPGQKLK 44
rne PRK10811
ribonuclease E; Reviewed
 85-240 1.21e-08

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 56.97  E-value: 1.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748   85 PETVLTTTVNEAEEVTEVEIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTVIASE 164
Cdd:PRK10811  880 EPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADI 959

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 907808748  165 EVAPSTGTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTttssEAKEVASSNGATAAVSTYQPE 240
Cdd:PRK10811  960 EEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEAT----VEHNHATAPMTRAPAPEYVPE 1031
LysM smart00257
Lysin motif;
49-90 2.11e-08

Lysin motif;


Pssm-ID: 197609 [Multi-domain]  Cd Length: 44  Bit Score: 49.75  E-value: 2.11e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 907808748    49 YTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLT 90
Cdd:smart00257   2 YTVKKGDTLSSIARRYGISVSDLLELNNILDPDNLQVGQKLK 43
LysM pfam01476
LysM domain; The LysM (lysin motif) domain is about 40 residues long. It is found in a variety ...
 49-90 4.13e-08

LysM domain; The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. The structure of this domain is known.


Pssm-ID: 396179 [Multi-domain]  Cd Length: 43  Bit Score: 48.93  E-value: 4.13e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 907808748   49 YTVQYGDTLSTIAEALGVDVTVLANLNKITNmDLIFPETVLT 90
Cdd:pfam01476   1 YTVKKGDTLSSIAKRYGITVEQLAELNGLSS-PNLYVGQKLK 41
LysM COG1388
LysM repeat [Cell wall/membrane/envelope biogenesis];
41-90 3.65e-07

LysM repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440998 [Multi-domain]  Cd Length: 156  Bit Score: 49.32  E-value: 3.65e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 907808748  41 TKTDNKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNmDLIFPETVLT 90
Cdd:COG1388  104 AAAPSPVTYTVKKGDTLWSIARRYGVSVEELKRWNGLSS-DTIRPGQKLK 152
rne PRK10811
ribonuclease E; Reviewed
 104-260 8.65e-07

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 51.19  E-value: 8.65e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748  104 IQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLS-QPIAEAPKEVASSSEVTKTVIASEEVAPSTGTSVP-----EE 177
Cdd:PRK10811  847 VVRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVsAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEViaapvTE 926

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748  178 QT---TETTRPVEEATPQETTPAEKQETQASPqAASAVEVTTTSSEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAA 254
Cdd:PRK10811  927 QPqviTESDVAVAQEVAEHAEPVVEPQDETAD-IEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQ 1005


                  ....*.
gi 907808748  255 PDYAGL 260
Cdd:PRK10811 1006 VPEATV 1011
XkdP COG1652
Cytoplasmic potassium-binding protein Kbp/XkdP/YgaU, contains LysM domain [Inorganic ion ...
 41-90 3.80e-04

Cytoplasmic potassium-binding protein Kbp/XkdP/YgaU, contains LysM domain [Inorganic ion transport and metabolism];


Pssm-ID: 441258 [Multi-domain]  Cd Length: 163  Bit Score: 40.76  E-value: 3.80e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 907808748  41 TKTDNKTSYTVQYGDTLSTIAEAL---GVDVTVLANLNK--ITNMDLIFPETVLT 90
Cdd:COG1652  104 LAPDAPKTYTVKPGDTLWGIAKRFygdPARWPEIAEANRdqIKNPDLIYPGQVLR 158
rne PRK10811
ribonuclease E; Reviewed
 132-293 3.86e-04

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 42.72  E-value: 3.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748  132 QTVQVADLSQPIAEAPKEVASSSEVTKTVIASEEVApstgtsVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASA 211
Cdd:PRK10811  851 QDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAP------VVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPV 924

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748  212 VEVT-----TTSSEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGL----AVAKSENAGLQPQTAAFKEEIA 282
Cdd:PRK10811  925 TEQPqviteSDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQpaapVVAEVAAEVETVTAVEPEVAPA 1004

                         170
                  ....*....|.
gi 907808748  283 NLFGITSFSGY 293
Cdd:PRK10811 1005 QVPEATVEHNH 1015
COG5373 COG5373
Uncharacterized membrane protein [Function unknown];
122-213 8.02e-04

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 444140 [Multi-domain]  Cd Length: 854  Bit Score: 41.52  E-value: 8.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748 122 LTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSE-VTKTVIASEEVAPSTGTSVPEEQTTETTRPVEEATPQETTPAEKQ 200
Cdd:COG5373   16 LVGLLGRVARLRRRVEELEAELAEAAEAASAPAEpEPEAAAAATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEA 95

                         90
                 ....*....|...
gi 907808748 201 ETQASPQAASAVE 213
Cdd:COG5373   96 EPAAAPAAASSFE 108
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 95-221 1.36e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 40.60  E-value: 1.36e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748  95 EAEEVTEVEIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTVIASEEVAPSTgtsv 174
Cdd:COG3266  241 TARLVLLLLIIGSALKAPSQASSASAPATTSLGEQQEVSLPPAVAAQPAAAAAAQPSAVALPAAPAAAAAAAAPAE---- 316

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 907808748 175 PEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEA 221
Cdd:COG3266  317 AAAPQPTAAKPVVTETAAPAAPAPEAAAAAAAPAAPAVAKKLAADEQ 363
PRK11907 PRK11907
bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;
162-248 1.89e-03

bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;


Pssm-ID: 237019 [Multi-domain]  Cd Length: 814  Bit Score: 40.22  E-value: 1.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748 162 ASEEVAPSTGTSVPEEQTTETTRPVEEATPQETTP---AEKQETQASPQAASAVEVTTTSSEAKEVASSNGATAAVSTYQ 238
Cdd:PRK11907  28 AEEIVTTTPATSTEAEQTTPVESDATEEADNTETPvaaTTAAEAPSSSETAETSDPTSEATDTTTSEARTVTPAATETSK 107

                         90
                 ....*....|....*
gi 907808748 239 PEE-----TKIISTT 248
Cdd:PRK11907 108 PVEgqtvdVRILSTT 122
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
 85-227 3.22e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 39.71  E-value: 3.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748  85 PETVLTTTVNEAEEVTEVEIQTPQADSSEEVTTATADltTNQVTVDDQtvqvadlsqPIAEAPKEVASSSEVTKTVIASE 164
Cdd:PRK14949 664 PDASQTSASFDLDPDFELATHQSVPEAALASGSAPAP--PPVPDPYDR---------PPWEEAPEVASANDGPNNAAEGN 732

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 907808748 165 EVAPSTGTSVPEEQTTETtrpveEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASS 227
Cdd:PRK14949 733 LSESVEDASNSELQAVEQ-----QATHQPQVQAEAQSPASTTALTQTSSEVQDTELNLVLLSS 790
PRK13914 PRK13914
invasion associated endopeptidase;
45-306 3.81e-03

invasion associated endopeptidase;


Pssm-ID: 237555 [Multi-domain]  Cd Length: 481  Bit Score: 39.01  E-value: 3.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748  45 NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETV-LTTTVNEAEEVTEVEIQTPQAdssEEVTTATADLT 123
Cdd:PRK13914 198 NATTHAVKSGDTIWALSVKYGVSVQDIMSWNNLSSSSIYVGQKLaIKQTANTATPKAEVKTEAPAA---EKQAAPVVKEN 274

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748 124 TNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTktviaseevAPSTGTSVPEEQTTETTRPVEEATPQETTPAEKQETQ 203
Cdd:PRK13914 275 TNTNTATTEKKETTTQQQTAPKAPTEAAKPAPAP---------STNTNANKTNTNTNTNTNNTNTSTPSKNTNTNTNSNT 345

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748 204 ASPQAasavevTTTSSEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQ-PQTAAfkEEIA 282
Cdd:PRK13914 346 NTNSN------TNANQGSSNNNSNSSASAIIAEAQKHLGKAYSWGGNGPTTFDCSGYTKYVFAKAGISlPRTSG--AQYA 417

                        250       260
                 ....*....|....*....|....*.
gi 907808748 283 NLFGItSFSGYRPGD--SGDHGKGLA 306
Cdd:PRK13914 418 STTRI-SESQAKPGDlvFFDYGSGIS 442
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 104-277 6.57e-03

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 38.74  E-value: 6.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748 104 IQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTVI----ASEEVAPSTGTSVPEEQT 179
Cdd:NF033609  32 LSSKEADASENSVTQSDSASNESKSNDSSSVSAAPKTDDTNVSDTKTSSNTNNGETSVaqnpAQQETTQSASTNATTEET 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748 180 TETTRPVEEATPQETTPAEKQETQA-SPQAASAVEVTTTSSEAKEVASSNG---ATAA--VSTYQPEETKIISTTYE-AP 252
Cdd:NF033609 112 PVTGEATTTATNQANTPATTQSSNTnAEELVNQTSNETTSNDTNTVSSVNSpqnSTNAenVSTTQDTSTEATPSNNEsAP 191

                        170       180
                 ....*....|....*....|....*
gi 907808748 253 AAPDYAGLAVAKSENAGLQPQTAAF 277
Cdd:NF033609 192 QSTDASNKDVVNQAVNTSAPRMRAF 216
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 143-229 8.91e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 38.25  E-value: 8.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907808748 143 IAEAPKEVASSSEVTKTVIASEEVAPSTGTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAK 222
Cdd:PRK14950 360 LVPVPAPQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRAAIPVD 439


                 ....*..
gi 907808748 223 EVASSNG 229
Cdd:PRK14950 440 EKPKYTP 446
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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