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Conserved domains on  [gi|907041289|emb|CTO22840|]
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choline binding protein D [Streptococcus pneumoniae]

Protein Classification

SH3 domain-containing protein( domain architecture ID 11467653)

SH3 domain-containing protein similar to Schizosaccharomyces pombe protein csh3 and Tip elongation aberrant protein Tea4

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
pneumo_PspA super family cl41532
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 310-448 1.43e-40

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


The actual alignment was detected with superfamily member NF033930:

Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 153.53  E-value: 1.43e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 310 WLSYtayNGSRRYIQLEG--------VTSSQNYQNQSG---------NISSY--GSNNSSTVGWKKINGSWYHFKSNGSK 370
Cdd:NF033930 485 WLQY---NGSWYYLNANGamatgwakVNGSWYYLNANGamatgwlqyNGSWYylNANGAMATGWLKYNGSWYYLNANGAM 561

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 371 STGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTG---------------------WYQVSGKWYYSYSSGA 429
Cdd:NF033930 562 ATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGwvkdgdtwyyleasgamkasqWFKVSDKWYYVNGLGA 641

                        170
                 ....*....|....*....
gi 907041289 430 LAVNTTVDGYRVNSDGERV 448
Cdd:NF033930 642 LAVNTTVDGYTVNANGEWV 660
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
91-448 1.66e-27

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


:

Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 114.58  E-value: 1.66e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289  91 IPAAYGNANEWGHRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRVIKANTMTGFI 170
Cdd:COG5263  100 VYDVYVVYEGGSVKDYGGGVSDDGDDVVDKTNVAAGGGGKTKKGDTNSANTGYLGDDLGGGTADKGGSAGYGAGKDGATA 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 171 HFKDLDGGSVGNSQSSTSTGGTHYFKTKSAiKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSYRYVQLE 250
Cdd:COG5263  180 AAKELVGSAADTYYGGASTYLTGDAGAYGA-LGLAAGSGAGAKKTGSTAGASGTAYGDSGGTAGSGLSSLGGSSNALESG 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 251 AVNKNPLGNSVLSSTGGTHYFKTKSAIKTEPLVSGTVIDYYYPGEKVHYDQI-------LEKDGYKWLSYTAYNGSRRYI 323
Cdd:COG5263  259 GENNQSLAGNGTSYDDAGAAGVDGTGTTGTVGWVDGKWYYFDAGKMVTGWQTingkwyyFDSDGAMATGWQKINGKWYYF 338

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 324 QLEGVTSSQnYQNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYY 403
Cdd:COG5263  339 DEDGAMATG-WVTDDGKWYYLGSDGAMATGWQKIDGKWYYFDSNGAMATGWVKVDGKWYYFDSSGAMATGWLKIDGKWYY 417

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 907041289 404 LGSSGAMKTGWYQVSGKWYYSYSSGALAVN-TTVDG--YRVNSDGERV 448
Cdd:COG5263  418 FDSDGAMATGWQKIGGKWYYFDSNGAMATGwVKVDGkwYYFDSDGAMA 465
 
Name Accession Description Interval E-value
pneumo_PspA NF033930
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 310-448 1.43e-40

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 153.53  E-value: 1.43e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 310 WLSYtayNGSRRYIQLEG--------VTSSQNYQNQSG---------NISSY--GSNNSSTVGWKKINGSWYHFKSNGSK 370
Cdd:NF033930 485 WLQY---NGSWYYLNANGamatgwakVNGSWYYLNANGamatgwlqyNGSWYylNANGAMATGWLKYNGSWYYLNANGAM 561

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 371 STGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTG---------------------WYQVSGKWYYSYSSGA 429
Cdd:NF033930 562 ATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGwvkdgdtwyyleasgamkasqWFKVSDKWYYVNGLGA 641

                        170
                 ....*....|....*....
gi 907041289 430 LAVNTTVDGYRVNSDGERV 448
Cdd:NF033930 642 LAVNTTVDGYTVNANGEWV 660
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 310-448 2.30e-40

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 153.24  E-value: 2.30e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 310 WLSYtayNGSRRYIQLEGVTSSQNYQNqsgNISSY--GSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLS 387
Cdd:NF033838 528 WLQN---NGSWYYLNANGSMATGWLQN---NGSWYylNANGAMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNAN 601

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 388 GEMQTGWLKENGS--------------------WYYLGSSGAMKTG-WYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGE 446
Cdd:NF033838 602 GDMATGWLQYNGSwyylnangsmatgwvkdgdtWYYLEASGAMKASqWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGE 681


                 ..
gi 907041289 447 RV 448
Cdd:NF033838 682 WV 683
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 311-448 1.13e-37

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 145.22  E-value: 1.13e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 311 LSYTAYNGSRRYIQL-EGVTSSQNYQNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGE 389
Cdd:NF033840 488 VSVTSNQGTDAAVEPaKPVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMATGWVQVNGSWYYLNSNGS 567

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 390 MQTGWLKENGSWYYLGSSGAMKTG---------------------WYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV 448
Cdd:NF033840 568 MATGWVQVDGSWYYLNDNGSMETGwlqnngswyylnsngsmkanqWFQVGSKWYYVNASGELAVNTSIDGYRVNDNGEWV 647
pneumo_PspA NF033930
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 344-445 4.44e-34

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 135.04  E-value: 4.44e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 344 YGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTGWYQVSGKWYY 423
Cdd:NF033930 455 YNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGWLQYNGSWYY 534

                         90       100
                 ....*....|....*....|....*
gi 907041289 424 SYSSGALAVN-TTVDG--YRVNSDG 445
Cdd:NF033930 535 LNANGAMATGwLKYNGswYYLNANG 559
pneumo_PspA NF033930
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 353-431 3.24e-32

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 129.65  E-value: 3.24e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 907041289 353 GWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALA 431
Cdd:NF033930 444 GWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMA 522
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 353-431 1.99e-30

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 124.35  E-value: 1.99e-30
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 907041289 353 GWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALA 431
Cdd:NF033838 487 GWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGAMA 565
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
91-448 1.66e-27

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 114.58  E-value: 1.66e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289  91 IPAAYGNANEWGHRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRVIKANTMTGFI 170
Cdd:COG5263  100 VYDVYVVYEGGSVKDYGGGVSDDGDDVVDKTNVAAGGGGKTKKGDTNSANTGYLGDDLGGGTADKGGSAGYGAGKDGATA 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 171 HFKDLDGGSVGNSQSSTSTGGTHYFKTKSAiKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSYRYVQLE 250
Cdd:COG5263  180 AAKELVGSAADTYYGGASTYLTGDAGAYGA-LGLAAGSGAGAKKTGSTAGASGTAYGDSGGTAGSGLSSLGGSSNALESG 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 251 AVNKNPLGNSVLSSTGGTHYFKTKSAIKTEPLVSGTVIDYYYPGEKVHYDQI-------LEKDGYKWLSYTAYNGSRRYI 323
Cdd:COG5263  259 GENNQSLAGNGTSYDDAGAAGVDGTGTTGTVGWVDGKWYYFDAGKMVTGWQTingkwyyFDSDGAMATGWQKINGKWYYF 338

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 324 QLEGVTSSQnYQNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYY 403
Cdd:COG5263  339 DEDGAMATG-WVTDDGKWYYLGSDGAMATGWQKIDGKWYYFDSNGAMATGWVKVDGKWYYFDSSGAMATGWLKIDGKWYY 417

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 907041289 404 LGSSGAMKTGWYQVSGKWYYSYSSGALAVN-TTVDG--YRVNSDGERV 448
Cdd:COG5263  418 FDSDGAMATGWQKIGGKWYYFDSNGAMATGwVKVDGkwYYFDSDGAMA 465
pneumo_PspA NF033930
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 372-445 2.31e-20

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 93.82  E-value: 2.31e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 907041289 372 TGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVN-TTVDG--YRVNSDG 445
Cdd:NF033930 443 TGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGwAKVNGswYYLNANG 519
SH3_5 pfam08460
Bacterial SH3 domain;
185-249 2.36e-19

Bacterial SH3 domain;


Pssm-ID: 430010 [Multi-domain]  Cd Length: 68  Bit Score: 81.66  E-value: 2.36e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 907041289  185 SSTSTGGTHYFKTKSAI---KTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSYRYVQL 249
Cdd:pfam08460   1 YYPSEQGTFTIGGKTGIvlrKNEPSLSAPVQFVLYKGDKVFYDQVLLADGYVWISYTSYNGVRRYLPV 68
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 372-431 5.33e-19

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 89.69  E-value: 5.33e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 372 TGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALA 431
Cdd:NF033838 486 TGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWLQNNGSWYYLNANGSMA 545
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
353-412 7.80e-12

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 67.20  E-value: 7.80e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 353 GWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKT 412
Cdd:COG5263  427 GWQKIGGKWYYFDSNGAMATGWVKVDGKWYYFDSDGAMATGWQTIDGKTYYFDSNGAWVG 486
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 391-431 5.96e-10

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 61.57  E-value: 5.96e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 907041289 391 QTGWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALA 431
Cdd:NF033838 485 KTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMA 525
PRK08581 PRK08581
amidase domain-containing protein;
74-168 1.77e-07

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 53.64  E-value: 1.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289  74 QCTSFVAFRLSNVNGfEIPAAYGNANEWGHRARREGYRVDNTPTIGSITWSTAGT------YGHVAWVSNVMGD-QIEIE 146
Cdd:PRK08581 512 QCTWYVYNRMKQFGT-SISGDLGDAHNWNNRAQARGYQVSHTPKRHAAVVFEAGQagadqhYGHVAFVEKVNSDgSIVIS 590

                         90       100
                 ....*....|....*....|..
gi 907041289 147 EYNYGYTESYNKRVIKANTMTG 168
Cdd:PRK08581 591 ESNVKGLGIISYRTIDAAAAEE 612
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 353-390 5.44e-06

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 43.30  E-value: 5.44e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 907041289  353 GWKKINGSWYHFKSNGSKSTGWLK--DGSSWYYLKLSGEM 390
Cdd:pfam19127   3 GWQTINGQTLYFDSDGKQVKGWVVtiDGKWYYFDADSGEM 42
 
Name Accession Description Interval E-value
pneumo_PspA NF033930
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 310-448 1.43e-40

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 153.53  E-value: 1.43e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 310 WLSYtayNGSRRYIQLEG--------VTSSQNYQNQSG---------NISSY--GSNNSSTVGWKKINGSWYHFKSNGSK 370
Cdd:NF033930 485 WLQY---NGSWYYLNANGamatgwakVNGSWYYLNANGamatgwlqyNGSWYylNANGAMATGWLKYNGSWYYLNANGAM 561

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 371 STGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTG---------------------WYQVSGKWYYSYSSGA 429
Cdd:NF033930 562 ATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGwvkdgdtwyyleasgamkasqWFKVSDKWYYVNGLGA 641

                        170
                 ....*....|....*....
gi 907041289 430 LAVNTTVDGYRVNSDGERV 448
Cdd:NF033930 642 LAVNTTVDGYTVNANGEWV 660
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 310-448 2.30e-40

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 153.24  E-value: 2.30e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 310 WLSYtayNGSRRYIQLEGVTSSQNYQNqsgNISSY--GSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLS 387
Cdd:NF033838 528 WLQN---NGSWYYLNANGSMATGWLQN---NGSWYylNANGAMATGWLQYNGSWYYLNANGDMATGWLQYNGSWYYLNAN 601

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 388 GEMQTGWLKENGS--------------------WYYLGSSGAMKTG-WYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGE 446
Cdd:NF033838 602 GDMATGWLQYNGSwyylnangsmatgwvkdgdtWYYLEASGAMKASqWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGE 681


                 ..
gi 907041289 447 RV 448
Cdd:NF033838 682 WV 683
PspC_relate_1 NF033840
PspC-related protein choline-binding protein 1; Members of this family share C-terminal ...
 311-448 1.13e-37

PspC-related protein choline-binding protein 1; Members of this family share C-terminal homology to the choline-binding form of the pneumococcal surface antigen PspC, but not to its allelic LPXTG-anchored forms because they lack the choline-binding repeat region. Members of this family should not be confused with PspC itself, whose identity and function reflect regions N-terminal to the choline-binding region. See Iannelli, et al. (PMID: 11891047) for information about the different allelic forms of PspC.


Pssm-ID: 411409 [Multi-domain]  Cd Length: 648  Bit Score: 145.22  E-value: 1.13e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 311 LSYTAYNGSRRYIQL-EGVTSSQNYQNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGE 389
Cdd:NF033840 488 VSVTSNQGTDAAVEPaKPVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMATGWVQVNGSWYYLNSNGS 567

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 390 MQTGWLKENGSWYYLGSSGAMKTG---------------------WYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV 448
Cdd:NF033840 568 MATGWVQVDGSWYYLNDNGSMETGwlqnngswyylnsngsmkanqWFQVGSKWYYVNASGELAVNTSIDGYRVNDNGEWV 647
pneumo_PspA NF033930
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 344-445 4.44e-34

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 135.04  E-value: 4.44e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 344 YGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTGWYQVSGKWYY 423
Cdd:NF033930 455 YNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGWLQYNGSWYY 534

                         90       100
                 ....*....|....*....|....*
gi 907041289 424 SYSSGALAVN-TTVDG--YRVNSDG 445
Cdd:NF033930 535 LNANGAMATGwLKYNGswYYLNANG 559
pneumo_PspA NF033930
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 353-431 3.24e-32

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 129.65  E-value: 3.24e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 907041289 353 GWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALA 431
Cdd:NF033930 444 GWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMA 522
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 353-431 1.99e-30

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 124.35  E-value: 1.99e-30
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 907041289 353 GWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALA 431
Cdd:NF033838 487 GWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGAMA 565
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
91-448 1.66e-27

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 114.58  E-value: 1.66e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289  91 IPAAYGNANEWGHRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRVIKANTMTGFI 170
Cdd:COG5263  100 VYDVYVVYEGGSVKDYGGGVSDDGDDVVDKTNVAAGGGGKTKKGDTNSANTGYLGDDLGGGTADKGGSAGYGAGKDGATA 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 171 HFKDLDGGSVGNSQSSTSTGGTHYFKTKSAiKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSYRYVQLE 250
Cdd:COG5263  180 AAKELVGSAADTYYGGASTYLTGDAGAYGA-LGLAAGSGAGAKKTGSTAGASGTAYGDSGGTAGSGLSSLGGSSNALESG 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 251 AVNKNPLGNSVLSSTGGTHYFKTKSAIKTEPLVSGTVIDYYYPGEKVHYDQI-------LEKDGYKWLSYTAYNGSRRYI 323
Cdd:COG5263  259 GENNQSLAGNGTSYDDAGAAGVDGTGTTGTVGWVDGKWYYFDAGKMVTGWQTingkwyyFDSDGAMATGWQKINGKWYYF 338

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 324 QLEGVTSSQnYQNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYY 403
Cdd:COG5263  339 DEDGAMATG-WVTDDGKWYYLGSDGAMATGWQKIDGKWYYFDSNGAMATGWVKVDGKWYYFDSSGAMATGWLKIDGKWYY 417

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 907041289 404 LGSSGAMKTGWYQVSGKWYYSYSSGALAVN-TTVDG--YRVNSDGERV 448
Cdd:COG5263  418 FDSDGAMATGWQKIGGKWYYFDSNGAMATGwVKVDGkwYYFDSDGAMA 465
COG3942 COG3942
Surface antigen [Cell wall/membrane/envelope biogenesis];
45-173 1.59e-26

Surface antigen [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443142 [Multi-domain]  Cd Length: 129  Bit Score: 103.53  E-value: 1.59e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289  45 NGSIARGDDYPayykngSQEIDQWRMYS-RQCTSFVAFRLsNVNGFEIPAAYGNANEWGHRARREGYRVDNTPTIGSITW 123
Cdd:COG3942    1 ARAASLGDGYP------PNVVDPWNGYPyGQCTWYAAWRR-AQLGGPIGSGWGNANNWADNARAAGYTVGSTPKVGAVAV 73

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 907041289 124 ST---AGTYGHVAWVSNVMGDQ-IEIEEYNYGYTESYNKRVIKANT--MTGFIHFK 173
Cdd:COG3942   74 FTpgvAGPYGHVAVVESVNSDGsILVSEMNWGGPGIYSTRTISAGNasSYGFIHPK 129
pneumo_PspA NF033930
pneumococcal surface protein A; The pneumococcal surface protein proteins, found in ...
 372-445 2.31e-20

pneumococcal surface protein A; The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.


Pssm-ID: 468251 [Multi-domain]  Cd Length: 660  Bit Score: 93.82  E-value: 2.31e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 907041289 372 TGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVN-TTVDG--YRVNSDG 445
Cdd:NF033930 443 TGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGwAKVNGswYYLNANG 519
SH3_5 pfam08460
Bacterial SH3 domain;
185-249 2.36e-19

Bacterial SH3 domain;


Pssm-ID: 430010 [Multi-domain]  Cd Length: 68  Bit Score: 81.66  E-value: 2.36e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 907041289  185 SSTSTGGTHYFKTKSAI---KTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSYRYVQL 249
Cdd:pfam08460   1 YYPSEQGTFTIGGKTGIvlrKNEPSLSAPVQFVLYKGDKVFYDQVLLADGYVWISYTSYNGVRRYLPV 68
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 372-431 5.33e-19

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 89.69  E-value: 5.33e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 372 TGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALA 431
Cdd:NF033838 486 TGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMATGWLQNNGSWYYLNANGSMA 545
SH3_5 pfam08460
Bacterial SH3 domain;
264-325 5.76e-19

Bacterial SH3 domain;


Pssm-ID: 430010 [Multi-domain]  Cd Length: 68  Bit Score: 80.51  E-value: 5.76e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 907041289  264 STGGTHYFKTKSAI---KTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQL 325
Cdd:pfam08460   4 SEQGTFTIGGKTGIvlrKNEPSLSAPVQFVLYKGDKVFYDQVLLADGYVWISYTSYNGVRRYLPV 68
COG5263 COG5263
Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];
353-412 7.80e-12

Glucan-binding domain (YG repeat) [Carbohydrate transport and metabolism];


Pssm-ID: 444077 [Multi-domain]  Cd Length: 486  Bit Score: 67.20  E-value: 7.80e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289 353 GWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAMKT 412
Cdd:COG5263  427 GWQKIGGKWYYFDSNGAMATGWVKVDGKWYYFDSDGAMATGWQTIDGKTYYFDSNGAWVG 486
CHAP pfam05257
CHAP domain; This domain corresponds to an amidase function. Many of these proteins are ...
 68-149 1.26e-10

CHAP domain; This domain corresponds to an amidase function. Many of these proteins are involved in cell wall metabolism of bacteria. This domain is found at the N-terminus of Swiss:P43675, where it functions as a glutathionylspermidine amidase EC:3.5.1.78. This domain is found to be the catalytic domain of PlyCA. CHAP is the amidase domain of bifunctional Escherichia coli glutathionylspermidine synthetase/amidase, and it catalyzes the hydrolysis of Gsp (glutathionylspermidine) into glutathione and spermidine.


Pssm-ID: 461605 [Multi-domain]  Cd Length: 83  Bit Score: 57.43  E-value: 1.26e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289   68 WRMYSRQCTSFVAFRLSNVNGFeipaaYGNANEWGHRARREGYRVDNTPTIGSITWSTAG----TYGHVAWVSNVMGDQI 143
Cdd:pfam05257   3 NGYPWGQCTWFVYWRVAQLGIY-----LGNAGDWADAAAGAYKVGSTTPKVGDIVVFDPGgggaSYGHVAIVEKVNDGSI 77


                  ....*.
gi 907041289  144 EIEEYN 149
Cdd:pfam05257  78 TVSEQN 83
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 391-431 5.96e-10

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 61.57  E-value: 5.96e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 907041289 391 QTGWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALA 431
Cdd:NF033838 485 KTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGAMA 525
PRK08581 PRK08581
amidase domain-containing protein;
74-168 1.77e-07

amidase domain-containing protein;


Pssm-ID: 236304 [Multi-domain]  Cd Length: 619  Bit Score: 53.64  E-value: 1.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 907041289  74 QCTSFVAFRLSNVNGfEIPAAYGNANEWGHRARREGYRVDNTPTIGSITWSTAGT------YGHVAWVSNVMGD-QIEIE 146
Cdd:PRK08581 512 QCTWYVYNRMKQFGT-SISGDLGDAHNWNNRAQARGYQVSHTPKRHAAVVFEAGQagadqhYGHVAFVEKVNSDgSIVIS 590

                         90       100
                 ....*....|....*....|..
gi 907041289 147 EYNYGYTESYNKRVIKANTMTG 168
Cdd:PRK08581 591 ESNVKGLGIISYRTIDAAAAEE 612
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 353-390 5.44e-06

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 43.30  E-value: 5.44e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 907041289  353 GWKKINGSWYHFKSNGSKSTGWLK--DGSSWYYLKLSGEM 390
Cdd:pfam19127   3 GWQTINGQTLYFDSDGKQVKGWVVtiDGKWYYFDADSGEM 42
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 392-434 9.61e-06

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 42.53  E-value: 9.61e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 907041289  392 TGWLKENGSWYYLGSSGAMKTGWY-QVSGKWYY-SYSSGALAVNT 434
Cdd:pfam19127   2 TGWQTINGQTLYFDSDGKQVKGWVvTIDGKWYYfDADSGEMVTNR 46
Choline_bind_3 pfam19127
Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to ...
 372-412 7.95e-05

Choline-binding repeat; Pair of presumed choline-binding repeats often found adjacent to pfam01473.


Pssm-ID: 465978 [Multi-domain]  Cd Length: 47  Bit Score: 39.83  E-value: 7.95e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 907041289  372 TGWLKDGSSWYYLKLSGEMQTGWLKE-NGSWYYL-GSSGAMKT 412
Cdd:pfam19127   2 TGWQTINGQTLYFDSDGKQVKGWVVTiDGKWYYFdADSGEMVT 44
Choline_bind_1 pfam01473
Putative cell wall binding repeat; These repeats are characterized by conserved aromatic ...
 392-410 1.81e-03

Putative cell wall binding repeat; These repeats are characterized by conserved aromatic residues and glycines are found in multiple tandem copies in a number of proteins. The CW repeat is 20 amino acid residues long. The exact domain boundaries may not be correct. It has been suggested that these repeats in Swiss:P15057 might be responsible for the specific recognition of choline-containing cell walls. Similar but longer repeats are found in the glucosyltransferases and glucan-binding proteins of oral streptococci and shown to be involved in glucan binding as well as in the related dextransucrases of Leuconostoc mesenteroides. Repeats also occur in toxins of Clostridium difficile and other clostridia, though the ligands are not always known.


Pssm-ID: 366661 [Multi-domain]  Cd Length: 19  Bit Score: 35.44  E-value: 1.81e-03
                          10
                  ....*....|....*....
gi 907041289  392 TGWLKENGSWYYLGSSGAM 410
Cdd:pfam01473   1 TGWVKINGNWYYFDSNGVM 19
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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