|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
1-457 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 640.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 1 MLLKQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSNR----IAILMDTKGPEVRTTANA 76
Cdd:PRK05826 1 RMLRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKlgrpVAILLDLKGPKIRVGKFK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 77 E-PIPYQIGERVKIVGNPDLETTRECIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDYLICEVQNEATLGSRKSVN 155
Cdd:PRK05826 81 EgKITLKTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGIN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 156 VPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAHNS-DIKIIAKIENQEGVDNIDEILEVADG 234
Cdd:PRK05826 161 IPGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCpHAKIIAKIERAEAVDNIDEIIEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 235 VMVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGK 314
Cdd:PRK05826 241 IMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 315 YPVEAVKTMTKIAAQAEKDkLEENDIRIPLNENSNDVTAFLAKQAVKATAKLKM-RAIITDSYSGRTARNLAAFRGKYPV 393
Cdd:PRK05826 321 YPVEAVEAMARICKGAEKE-FSINLSKHRLDRQFDRIDEAIAMSAMYAANHLKGvKAIVALTESGRTARLISRFRPGAPI 399
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 933275177 394 LAICYKEKTMRHLALSYGVEAIYMPELANGQEYYFAALRRLLKEGRLQPADMVGYLSSGKAGTQ 457
Cdd:PRK05826 400 FAVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTA 463
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
3-466 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 628.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 3 LKQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSNR----IAILMDTKGPEVRTTANAE- 77
Cdd:COG0469 2 MRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKElgrpVAILLDLQGPKIRTGKFKEg 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 78 PIPYQIGERVKIVGNPDlETTRECIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDYLICEVQNEATLGSRKSVNVP 157
Cdd:COG0469 82 PVELKKGDTFTLTTDDV-EGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 158 GVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAHNSDIKIIAKIENQEGVDNIDEILEVADGVMV 237
Cdd:COG0469 161 GVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGIMV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 238 ARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPV 317
Cdd:COG0469 241 ARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 318 EAVKTMTKIAAQAEKDKLEENDIRIPLNENSNDVTAFLAKQAVKATAKLKMRAIITDSYSGRTARNLAAFRGKYPVLAIC 397
Cdd:COG0469 321 EAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILALT 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 933275177 398 YKEKTMRHLALSYGVEAIYMPELANGQEYYFAALRRLLKEGRLQPADMVGYLSS---GKAGTqTSFLEINVV 466
Cdd:COG0469 401 PNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGvpvGVPGT-TNTLKVHRV 471
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
4-463 |
3.70e-177 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 505.28 E-value: 3.70e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 4 KQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVS----NRIAILMDTKGPEVRT-TANAEP 78
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAeklgRPVAILLDTKGPEIRTgEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 79 IPYQIGERVKIVGNPD-LETTRECIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDYLICEVQNEATLGSRKSVNVP 157
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIkGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 158 GVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAHN-SDIKIIAKIENQEGVDNIDEILEVADGVM 236
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGaKDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 237 VARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYP 316
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 317 VEAVKTMTKIAAQAEK--DKLEENDIRIPLNENSNDVTAFLAKQAVKATAKLKMRAIITDSYSGRTARNLAAFRGKYPVL 394
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKalAYLTNFNDRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 933275177 395 AICYKEKTMRHLALSYGVEAIYMPELAN-GQEYYFAALRRLLKEGRLQPADMVGYLSSGKAGT--QTSFLEI 463
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLVDEEPSdTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGegGTNTIRV 472
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
3-466 |
1.04e-165 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 476.42 E-value: 1.04e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 3 LKQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSNR----IAILMDTKGPEVRT--TANA 76
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKtggpVAIALDTKGPEIRTglFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 77 EPIPYQIGERVKIVGNP-DLETTRECIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDY-LICEVQNEATLGSRKSV 154
Cdd:cd00288 81 KDISLKAGDKFLVTTDPaAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKtLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 155 NVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAHNSDIKIIAKIENQEGVDNIDEILEVADG 234
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 235 VMVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGK 314
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 315 YPVEAVKTMTKIAAQAEKdKLEENDIRIPLN---ENSNDVTAFLAKQAVKATAKLKMRAIITDSYSGRTARNLAAFRGKY 391
Cdd:cd00288 321 YPVEAVKAMARICLEAEK-ALSHRVLFNEMRrltPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 392 PVLAICYKEKTMRHLALSYGVEAIYMPE----LANGQEYYF-AALRRLLKEGRLQPADMVGYLSSGKAGT-QTSFLEINV 465
Cdd:cd00288 400 PIIAVTRNEQTARQLHLYRGVYPVLFEEpkpgWQEDTDARLkAAVNVAKEKGLLKKGDLVVVVQGWPVGSgSTNTMRILT 479
|
.
gi 933275177 466 V 466
Cdd:cd00288 480 V 480
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
3-332 |
8.34e-140 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 405.60 E-value: 8.34e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 3 LKQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSNR----IAILMDTKGPEVRT---TAN 75
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKtggtVAIALDTKGPEIRTgntKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 76 AEPIPYQIGERVKIVGNPDLET--TRECIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDD-YLICEVQNEATLGSRK 152
Cdd:pfam00224 81 KKDIELKAGDEMIVSTDAKYKGacDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDkTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 153 SVNVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAHNSDIKIIAKIENQEGVDNIDEILEVA 232
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 233 DGVMVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAY 312
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330 340
....*....|....*....|
gi 933275177 313 GKYPVEAVKTMTKIAAQAEK 332
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAEK 340
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
1-457 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 640.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 1 MLLKQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSNR----IAILMDTKGPEVRTTANA 76
Cdd:PRK05826 1 RMLRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKlgrpVAILLDLKGPKIRVGKFK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 77 E-PIPYQIGERVKIVGNPDLETTRECIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDYLICEVQNEATLGSRKSVN 155
Cdd:PRK05826 81 EgKITLKTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGIN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 156 VPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAHNS-DIKIIAKIENQEGVDNIDEILEVADG 234
Cdd:PRK05826 161 IPGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCpHAKIIAKIERAEAVDNIDEIIEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 235 VMVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGK 314
Cdd:PRK05826 241 IMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 315 YPVEAVKTMTKIAAQAEKDkLEENDIRIPLNENSNDVTAFLAKQAVKATAKLKM-RAIITDSYSGRTARNLAAFRGKYPV 393
Cdd:PRK05826 321 YPVEAVEAMARICKGAEKE-FSINLSKHRLDRQFDRIDEAIAMSAMYAANHLKGvKAIVALTESGRTARLISRFRPGAPI 399
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 933275177 394 LAICYKEKTMRHLALSYGVEAIYMPELANGQEYYFAALRRLLKEGRLQPADMVGYLSSGKAGTQ 457
Cdd:PRK05826 400 FAVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTA 463
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
3-466 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 628.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 3 LKQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSNR----IAILMDTKGPEVRTTANAE- 77
Cdd:COG0469 2 MRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKElgrpVAILLDLQGPKIRTGKFKEg 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 78 PIPYQIGERVKIVGNPDlETTRECIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDYLICEVQNEATLGSRKSVNVP 157
Cdd:COG0469 82 PVELKKGDTFTLTTDDV-EGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 158 GVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAHNSDIKIIAKIENQEGVDNIDEILEVADGVMV 237
Cdd:COG0469 161 GVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGIMV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 238 ARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPV 317
Cdd:COG0469 241 ARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 318 EAVKTMTKIAAQAEKDKLEENDIRIPLNENSNDVTAFLAKQAVKATAKLKMRAIITDSYSGRTARNLAAFRGKYPVLAIC 397
Cdd:COG0469 321 EAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILALT 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 933275177 398 YKEKTMRHLALSYGVEAIYMPELANGQEYYFAALRRLLKEGRLQPADMVGYLSS---GKAGTqTSFLEINVV 466
Cdd:COG0469 401 PNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGvpvGVPGT-TNTLKVHRV 471
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
4-463 |
3.70e-177 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 505.28 E-value: 3.70e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 4 KQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVS----NRIAILMDTKGPEVRT-TANAEP 78
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAeklgRPVAILLDTKGPEIRTgEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 79 IPYQIGERVKIVGNPD-LETTRECIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDYLICEVQNEATLGSRKSVNVP 157
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIkGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 158 GVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAHN-SDIKIIAKIENQEGVDNIDEILEVADGVM 236
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGaKDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 237 VARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYP 316
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 317 VEAVKTMTKIAAQAEK--DKLEENDIRIPLNENSNDVTAFLAKQAVKATAKLKMRAIITDSYSGRTARNLAAFRGKYPVL 394
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKalAYLTNFNDRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 933275177 395 AICYKEKTMRHLALSYGVEAIYMPELAN-GQEYYFAALRRLLKEGRLQPADMVGYLSSGKAGT--QTSFLEI 463
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLVDEEPSdTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGegGTNTIRV 472
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
3-466 |
1.04e-165 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 476.42 E-value: 1.04e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 3 LKQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSNR----IAILMDTKGPEVRT--TANA 76
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKtggpVAIALDTKGPEIRTglFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 77 EPIPYQIGERVKIVGNP-DLETTRECIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDY-LICEVQNEATLGSRKSV 154
Cdd:cd00288 81 KDISLKAGDKFLVTTDPaAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKtLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 155 NVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAHNSDIKIIAKIENQEGVDNIDEILEVADG 234
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 235 VMVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGK 314
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 315 YPVEAVKTMTKIAAQAEKdKLEENDIRIPLN---ENSNDVTAFLAKQAVKATAKLKMRAIITDSYSGRTARNLAAFRGKY 391
Cdd:cd00288 321 YPVEAVKAMARICLEAEK-ALSHRVLFNEMRrltPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 392 PVLAICYKEKTMRHLALSYGVEAIYMPE----LANGQEYYF-AALRRLLKEGRLQPADMVGYLSSGKAGT-QTSFLEINV 465
Cdd:cd00288 400 PIIAVTRNEQTARQLHLYRGVYPVLFEEpkpgWQEDTDARLkAAVNVAKEKGLLKKGDLVVVVQGWPVGSgSTNTMRILT 479
|
.
gi 933275177 466 V 466
Cdd:cd00288 480 V 480
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
1-470 |
2.48e-154 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 451.69 E-value: 2.48e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 1 MLLKQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSNR----IAILMDTKGPEVRTTANA 76
Cdd:PRK06354 5 DLMRRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKlgktVGILQDLQGPKIRLGRFE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 77 E-PIPYQIGERVkIVGNPDLETTRECIAVSYPNFVRDLNVGGTILIDDGDLELRV--IDKTDDYLICEVQNEATLGSRKS 153
Cdd:PRK06354 85 DgPIELKTGDEF-ILTSREVLGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVeeVDKADGELHCKVLVGGVLSNKKG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 154 VNVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAHN-SDIKIIAKIENQEGVDNIDEILEVA 232
Cdd:PRK06354 164 VNFPGVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEHNgKHIPIIAKIEKQEAIDNIDAILELC 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 233 DGVMVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAY 312
Cdd:PRK06354 244 DGLMVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSNETAA 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 313 GKYPVEAVKTMTKIAAQAEKDkLEENDIRIPLNENSNDVTAFLAkQAVKATA-KLKMRAIITDSYSGRTARNLAAFRGKY 391
Cdd:PRK06354 324 GDYPVEAVQTMATIAVRIEKD-LPYRDILSKRPEFTTTITNAIS-QAVSHIAlQLDAAAIVTLTKSGATARNVSKYRPKT 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 392 PVLAICYKEKTMRHLALSYGVEAIYMPELANGQEYYFAALRRLLKEGRLQPADMV----GYLsSGKAGTqTSFLEINVVE 467
Cdd:PRK06354 402 PILAVTPNESVARRLQLVWGVTPLLVLDAPSTDETFDAAINVAQESGLLKQGDLVvitaGTL-VGESGS-TDLMKVHVVG 479
|
...
gi 933275177 468 DAL 470
Cdd:PRK06354 480 AVV 482
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
3-446 |
6.24e-150 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 436.02 E-value: 6.24e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 3 LKQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSN----RIAILMDTKGPEVRTT--ANA 76
Cdd:PRK09206 1 MKKTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSktgkKAAILLDTKGPEIRTMklEGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 77 EPIPYQIGERV------KIVGNPdlettrECIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDYLICEVQNEATLGS 150
Cdd:PRK09206 81 NDVSLKAGQTFtfttdkSVVGNK------ERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLGE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 151 RKSVNVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAHN-SDIKIIAKIENQEGVDNIDEIL 229
Cdd:PRK09206 155 NKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHGgENIQIISKIENQEGLNNFDEIL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 230 EVADGVMVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGE 309
Cdd:PRK09206 235 EASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGE 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 310 TAYGKYPVEAVKTMTKIAAQAekDKLEENDIRIPLNENSNDVTAFLAKQAVKATAKLKMRAIITDSYSGRTARNLAAFRG 389
Cdd:PRK09206 315 SAKGKYPLEAVSIMATICERT--DRVMNSRLESNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYFP 392
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 933275177 390 KYPVLAICYKEKTMRHLALSYGVEAIYMPELANGQEYYFAALRRLLKEGRLQPADMV 446
Cdd:PRK09206 393 DATILALTTNEKTARQLVLSKGVVPQLVKEIASTDDFYRLGKELALQSGLAQKGDVV 449
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
3-332 |
8.34e-140 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 405.60 E-value: 8.34e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 3 LKQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSNR----IAILMDTKGPEVRT---TAN 75
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKtggtVAIALDTKGPEIRTgntKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 76 AEPIPYQIGERVKIVGNPDLET--TRECIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDD-YLICEVQNEATLGSRK 152
Cdd:pfam00224 81 KKDIELKAGDEMIVSTDAKYKGacDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDkTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 153 SVNVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAHNSDIKIIAKIENQEGVDNIDEILEVA 232
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 233 DGVMVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAY 312
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330 340
....*....|....*....|
gi 933275177 313 GKYPVEAVKTMTKIAAQAEK 332
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAEK 340
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
3-446 |
6.39e-128 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 380.04 E-value: 6.39e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 3 LKQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSNR----IAILMDTKGPEVRTTANAE- 77
Cdd:PRK06247 4 NRRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDEtgrpIGILADLQGPKLRLGRFADg 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 78 PIPYQIGERVKIVGNpDLETTRECIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDYLICEVQNEATLGSRKSVNVP 157
Cdd:PRK06247 84 KVQLANGQTFRLDVD-DAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVSLP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 158 GVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILdahNSDIKIIAKIENQEGVDNIDEILEVADGVMV 237
Cdd:PRK06247 163 GTVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKII---GGRVPVMAKIEKPQAIDRLEAIVEASDAIMV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 238 ARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPV 317
Cdd:PRK06247 240 ARGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKYPV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 318 EAVKTMTKIAAQAEKDKLEENDI---RIPLNENSNDVTAFLAKQAVKataKLKMRAIITDSYSGRTARNLAAFRGKYPVL 394
Cdd:PRK06247 320 EAVRTMARIIRQVERDPTYPPLIhaqRPQPEATKRDAISYAARDIAE---RLDLAALVAYTSSGDTALRAARERPPLPIL 396
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 933275177 395 AICYKEKTMRHLALSYGVEAIYMPELANGQEYYFAALRRLLKEGRLQPADMV 446
Cdd:PRK06247 397 ALTPNPETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRV 448
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
4-446 |
1.84e-126 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 377.40 E-value: 1.84e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 4 KQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSN----RIAILMDTKGPEVRT--TANAE 77
Cdd:PLN02461 21 PKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMAntgiLCAVMLDTKGPEIRTgfLKDGK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 78 PIPYQIGERVKIVGNPDLETTRECIAVSYPNFVRDLNVGGTILIDDGDLELRVI--DKTDDYLICEVQNEATLGSRKSVN 155
Cdd:PLN02461 101 PVQLKQGQEITITTDYSIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLscDVEAGTVRCRCENSAMLGERKNVN 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 156 VPGVRINLPSLTEKDRNNIL-YAIEKDIDFIAHSFVRNRQDVLDIREILDAHNSDIKIIAKIENQEGVDNIDEILEVADG 234
Cdd:PLN02461 181 LPGVVVDLPTLTEKDKEDILqWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLISKVENQEGLDNFDDILAESDA 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 235 VMVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGK 314
Cdd:PLN02461 261 FMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGA 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 315 YPVEAVKTMTKIAAQAE---------KDKLEENDIRIPLNENsndvtafLAKQAVKATAKLKMRAIITDSYSGRTARNLA 385
Cdd:PLN02461 341 YPELAVKTMARICREAEasldygalfKEIMRSAPLPMSPLES-------LASSAVRTANKVKASLIVVLTRGGTTARLVA 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 386 AFRGKYPVLAICYKEKTMRHLALSYGVEA------IY---MPELANG----------QEYYFAALRRLLKEGRLQPADMV 446
Cdd:PLN02461 414 KYRPAVPILSVVVPEITTDSFDWSCSDEAparhslIYrglIPVLAEGsakatdsestEEILEAAIEHAKKKGLCKPGDSV 493
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
4-438 |
6.12e-126 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 376.41 E-value: 6.12e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 4 KQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAV-----SNRIAILMDTKGPEVRT--TANA 76
Cdd:PTZ00066 38 KKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAakarpNANLGILLDTKGPEIRTgfLKNH 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 77 EPIPYQIGERVKIVGNPDLETTRECIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDYLICEVQNEATLGSRKSVNV 156
Cdd:PTZ00066 118 KPITLKEGQTLKITTDYTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGERKNMNL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 157 PGVRINLPSLTEKDRNNIL-YAIEKDIDFIAHSFVRNRQDVLDIREILDAHNSDIKIIAKIENQEGVDNIDEILEVADGV 235
Cdd:PTZ00066 198 PGVKVELPVIGEKDKNDILnFAIPMGCDFIALSFVQSADDVRLCRQLLGERGRHIKIIPKIENIEGLINFDEILAESDGI 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 236 MVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKY 315
Cdd:PTZ00066 278 MVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGETANGKF 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 316 PVEAVKTMTKIAAQAEKDKLEENDIRIPLNENSNDVTA--FLAKQAVKATAKLKMRAIITDSYSGRTARNLAAFRGKYPV 393
Cdd:PTZ00066 358 PVEAVNIMAKICFEAETCIDYRVLYHAIHLAVPTPVSVqeAVARSAVETAEDINAKLIIALTETGNTARLISKYRPSCTI 437
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 933275177 394 LAICYKEKTMRHLALSYGVEAIYMPELANGQEYYFAAL-----RRLLKEG 438
Cdd:PTZ00066 438 LALSASPSVVKSLSVARGVTTYVVNSFQGTDVVIRNAIalakeRGLVESG 487
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
30-416 |
3.68e-106 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 323.54 E-value: 3.68e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 30 MNVVRMNTAHASREGFEALIANVRAVSNR----IAILMDTKGPEVRT------TANAEPipyqiGERVKIVGNPDLET-- 97
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAElgvnIAIALDTKGPEIRTglfvggEAVMER-----GATCYVTTDPAFADkg 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 98 TRECIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDY-LICEVQNEATLGSRKSVNVPGVRINLPSLTEKDRNNILY 176
Cdd:PTZ00300 76 TKDKFYIDYQNLSKVVRPGGYIYIDDGILILHVQSHEDEQtLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCADLQF 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 177 AIEKDIDFIAHSFVRNRQDVLDIREILDAHNSDIKIIAKIENQEGVDNIDEILEVADGVMVARGDLGIEVPQERIPGIQR 256
Cdd:PTZ00300 156 GVEQGVDMIFASFIRSAEQVGEVRKALGAKGGDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQK 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 257 TLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPVEAVKTMTKIAAQAEKDKLE 336
Cdd:PTZ00300 236 ILISKCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSAVNE 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 337 E---NDIR----IPLNensndVTAFLAKQAVKATAKLKMRAIITDSYSGRTARNLAAFRGKYPVLAICYKEKTMRHLALS 409
Cdd:PTZ00300 316 YvffNSIKklqpIPMS-----AEEAVCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNIT 390
|
....*..
gi 933275177 410 YGVEAIY 416
Cdd:PTZ00300 391 QGVESVF 397
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
4-453 |
3.02e-104 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 322.65 E-value: 3.02e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 4 KQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIA-----NVRAVSNRIAILMDTKGPEVRTTANAEP 78
Cdd:PLN02623 110 RKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDlvkeyNAQSKDNVIAIMLDTKGPEVRSGDLPQP 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 79 IPYQIGERVKI-----VGNPDlettreCIAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDYLICEVQNEATLGSRKS 153
Cdd:PLN02623 190 IMLEEGQEFTFtikrgVSTED------CVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKTSDSVKCEVVDGGELKSRRH 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 154 VNVPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAHNSDIKIIAKIENQEGVDNIDEILEVAD 233
Cdd:PLN02623 264 LNVRGKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNADIHVIVKIESADSIPNLHSIITASD 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 234 GVMVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYG 313
Cdd:PLN02623 344 GAMVARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHG 423
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 314 KYPVEAVKTMTKIAAQAEKDKLEENDIRIPLNENSNDVTAFLAKQAVKATAKLKMrAIITDSYSGRTARNLAAFRGKYPV 393
Cdd:PLN02623 424 KFPLKAVKVMHTVALRTEATLPEGTTPPNLGQAFKNHMSEMFAFHATMMANTLGT-SIIVFTRTGFMAILLSHYRPSGTI 502
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 394 LAICYKEKTMRHLALSYGVEAIYMPELANGQEYYFAALRRLLKEGRLQPADMVGYLSSGK 453
Cdd:PLN02623 503 FAFTNEKRIQQRLALYQGVCPIYMQFSDDAEETFARALSLLLNKGMVKEGEEVALVQSGR 562
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
6-402 |
2.98e-84 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 269.23 E-value: 2.98e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 6 TKIVASISDRRCDVDFIKQLFDAGMNVVRMN----TAHASREGFEALIANVRAVSNRIAILMDTKGPEVRTTANAE-PIP 80
Cdd:PLN02765 30 TKIVGTLGPKSRSVEVIEACLKAGMSVARFDfswgDAEYHQETLENLKIAVKNTKKLCAVMLDTVGPELQVINKTEkPIS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 81 YQIGERVKIVGNPDLETTRECIAVSYPNFVRDLNVGGTILI--------DDGDLELRVIDKTDDYLICEVQNEATL-GSR 151
Cdd:PLN02765 110 LKAGNTVTLTPDQSKEASSEVLPINFPGLAKAVKPGDTIFVgqylftgsETTSVWLEVDEVKGDDVVCTVKNSATLaGSL 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 152 KSVNVPGVRINLPSLTEKDRNNI-LYAIEKDIDFIAHSFVRNRQDVLDIREILDAHN-SDIKIIAKIENQEGVDNIDEIL 229
Cdd:PLN02765 190 FTLHVSQVRIDLPTLSEKDKEVIsTWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGlSQTQIFAKIENVEGLTHFDEIL 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 230 EVADGVMVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVaTQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGE 309
Cdd:PLN02765 270 QEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAVLDGADAILLGAE 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 310 TAYGKYPVEAVKTMTKIAAQAEKDKLEENDIRI---PLNENSNDVTAfLAKQAVKATAKLKMRAIITDSYSGRTARNLAA 386
Cdd:PLN02765 349 TLRGLYPVETISTVGRICAEAEKVFNQDLYFKKtvkYVGEPMSHLES-IASSAVRAAIKVKASVIIVFTSSGRAARLIAK 427
|
410
....*....|....*..
gi 933275177 387 FRGKYPVLA-ICYKEKT 402
Cdd:PLN02765 428 YRPTMPVLSvVIPRLKT 444
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
14-331 |
1.35e-82 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 259.49 E-value: 1.35e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 14 DRRCDV-------DFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSNRIAILMDTKGPEVRT-TANAEPIPYQIGE 85
Cdd:PRK06739 4 DRICTIgpasnnkETLAQLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDSIKILGDVQGPKIRLgEIKGEQITLQAGD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 86 RVKIVGNPDLETTRECiAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDYLICEVQNEATLGSRKSVNVPGVRINLPS 165
Cdd:PRK06739 84 SFILHTQPVTGSSTEA-SVDYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVRLPA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 166 LTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIRE-ILDAHNSDIKIIAKIENQEGVDNIDEILEVADGVMVARGDLGI 244
Cdd:PRK06739 163 ITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDfIQQYKETSPNLIAKIETMEAIENFQDICKEADGIMIARGDLGV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 245 EVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPVEAVKTMT 324
Cdd:PRK06739 243 ELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPIESVSTLR 322
|
....*..
gi 933275177 325 KIAAQAE 331
Cdd:PRK06739 323 LVSEFAE 329
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
3-446 |
7.91e-75 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 244.27 E-value: 7.91e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 3 LKQTKIVASISDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSNR----IAILMDTKGPEVR------- 71
Cdd:PLN02762 24 TRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEkgfaVAVMMDTEGSEIHmgdlgga 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 72 TTANAEPipyqiGErVKIVGNPDLETTREC--IAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDYLICEVQNEATLG 149
Cdd:PLN02762 104 SSAKAED-----GE-EWTFTVRKFDGSRPEftIQVNYDGFAEDVKVGDELVVDGGMVRFEVIEKIGPDVKCKCTDPGLLL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 150 SRKSVN-------VPGVRINLPSLTEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIREILDAH--NSDIKIIAKIENQE 220
Cdd:PLN02762 178 PRANLTfwrdgslVRERNAMLPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAARsrDSDIGVIAKIESLD 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 221 GVDNIDEILEVADGVMVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYR 300
Cdd:PLN02762 258 SLKNLEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEAVRQR 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 301 TDALMLSGETAYGKYPVEAVKTMTKIAAQAEKDKLEEN-DIRIPLNENSNDVTAFLAKQ----AVKATAKLKMRAIITDS 375
Cdd:PLN02762 338 ADALMLSGESAMGLYPEKALSVLRSVSLRMELWSREEKrHEALELPQLSSSLSDRISEEicnsAAKMANNLGVDAIFVYT 417
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 933275177 376 YSGRTARNLAAFRGKYPVLAICYKEKTMRHLALSYGVEAIYMPeLANGQEYYFAALRRLLK-EGRLQPADMV 446
Cdd:PLN02762 418 KHGHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGLIPFRLD-FSDDMESNLNKTFSLLKaRGMIKSGDLV 488
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
13-320 |
1.52e-59 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 203.32 E-value: 1.52e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 13 SDRRCDVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVR----AVSNRIAILMDTKGPEVRTTANAEPIPY---QIGE 85
Cdd:PRK08187 143 SEAADDPDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRqaerATGRRCKILMDLAGPKIRTGAVAGPLGKtrlYTGD 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 86 RVKIVGNPDLETTREC---IAVSYPNFVRDLNVGGTILIDDGDLELRVIDKTDDYLICEVQNEATLGSR----KSVNVPG 158
Cdd:PRK08187 223 RLALVAQGPPRRIDEEhfqVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGGALLEVTHARPKGLKlkpeKGLNFPD 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 159 VRINLPSLTEKDRnnilyaieKDIDFIA-------HSFVRNRQDV------LDIREILDAHnsDIKIIAKIENQEGVDNI 225
Cdd:PRK08187 303 TALDLPALTEKDR--------ADLDFVArhadlvgYSFVQSPGDVealqaaLAARRPDDWR--KLGLVLKIETPRAVANL 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 226 DEILEVADG-----VMVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAiyYR 300
Cdd:PRK08187 373 PELIVQAAGrqpfgVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTDAAMA--AR 450
|
330 340
....*....|....*....|
gi 933275177 301 TDALMLSGetayGKYPVEAV 320
Cdd:PRK08187 451 AECVMLNK----GPYLVEAV 466
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
18-326 |
1.62e-43 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 162.04 E-value: 1.62e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 18 DVDFIKQLFDAGMNVVRMNTAHASREGFEALIANVRAVSNR----IAILMDTKGPEVRT--------------------- 72
Cdd:PRK14725 154 DPDLVRRLLAAGMDIARINCAHDDPEAWRAMIANVRTAEEElgrrCRIAMDLAGPKLRTgpiapgprviklrptrdalgr 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 73 ---------TANAEPIP------------------YQIGERV-------------------------------------- 87
Cdd:PRK14725 234 vltparlwlTASESPPPspppgpvglpvdpewlarLEPGDELrftdargkkrkltvtevddegvlaegsqtaylangtll 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 88 --------KIVGNPDLET------------TRECIAV--------------SYPNFVRDLNVGGTILIDDGDLELRVIDK 133
Cdd:PRK14725 314 rlgrhdstRVGGLPPVEQklrlkvgdrlvlTRDDAPGdpaqgdappariscTLPEAFRAARVGERVWFDDGKIGAVVVKV 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 134 TDDYLICEVQNEATLGSR----KSVNVPGVRINLPSLTEKDRNNiLYAIEKDIDFIAHSFVRNRQDVLDIREILDAHN-S 208
Cdd:PRK14725 394 EADEVELRITHARPGGSKlkagKGINLPDSHLPLPALTDKDLED-LAFVAKHADIVALSFVRSPEDVRLLLDALEKLGaD 472
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 209 DIKIIAKIENQEGVDNIDEILEVA-----DGVMVARGDLGIEVPQERIPGIQRTLIRKCVLAKKPVIVATQMLHTMINNP 283
Cdd:PRK14725 473 DLGVVLKIETRRAFENLPRILLEAmrhprFGVMIARGDLAVEVGFERLAEVQEEILWLCEAAHVPVIWATQVLESLAKKG 552
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 933275177 284 RPTRAEVTDIANAIyyRTDALMLSGetayGKYPVEAVKTMTKI 326
Cdd:PRK14725 553 LPSRAEITDAAMAL--RAECVMLNK----GPHIVEAVRVLDDI 589
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
261-446 |
2.55e-40 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 147.35 E-value: 2.55e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 261 KCVLAKKPVIVATQMLHTMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPVEAVKTMTKIAAQAEKDKLEENDI 340
Cdd:COG3848 1 KCNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDLEYREQR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 341 RIPLNENSNDVTAFLAKQAVKATAKLKMRAIITDSYSGRTARNLAAFRGKYPVLAICYKEKTMRHLALSYGVEAIYMPEL 420
Cdd:COG3848 81 VPRAKESSTTITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAVTPSERVARQLSLVWGVYPLLVEES 160
|
170 180
....*....|....*....|....*.
gi 933275177 421 ANGQEYYFAALRRLLKEGRLQPADMV 446
Cdd:COG3848 161 ASTDEMFAVAVALALEAGLVKDGDLV 186
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
355-446 |
1.64e-15 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 72.51 E-value: 1.64e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 355 LAKQAVKATAKLKMRAIITDSYSGRTARNLAAFRGKYPVLAICYKEKTMRHLALSYGVEAIYMPELANGQEYYFAALRRL 434
Cdd:pfam02887 3 IAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDEAETTDEMLRRAVKVA 82
|
90
....*....|..
gi 933275177 435 LKEGRLQPADMV 446
Cdd:pfam02887 83 KEAGLVKKGDLV 94
|
|
| PRK10558 |
PRK10558 |
alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional |
207-242 |
3.96e-04 |
|
alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional
Pssm-ID: 182547 Cd Length: 256 Bit Score: 42.03 E-value: 3.96e-04
10 20 30
....*....|....*....|....*....|....*...
gi 933275177 207 NSDIKIIAKIENQEGVDNIDEI--LEVADGVMVARGDL 242
Cdd:PRK10558 143 NKNITVLVQIESQQGVDNVDAIaaTEGVDGIFVGPSDL 180
|
|
| HpcH_HpaI |
pfam03328 |
HpcH/HpaI aldolase/citrate lyase family; This family includes 2,4-dihydroxyhept-2-ene-1, ... |
157-293 |
1.02e-03 |
|
HpcH/HpaI aldolase/citrate lyase family; This family includes 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase and 4-hydroxy-2-oxovalerate aldolase.
Pssm-ID: 427247 [Multi-domain] Cd Length: 221 Bit Score: 40.42 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 933275177 157 PGVRINL--PSLTEKDrnniLYAIEKDIDFIAHSFVRNRQDVLDIREILDAH-------NSDIKIIAKIENQEGVDNIDE 227
Cdd:pfam03328 62 VVVRVNSldSPFGKQD----LAVLDLGAQVVLVPKVETAEDARAAVSAIRYPpkgirraNGNTCLLAQIESALGVLNADE 137
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 933275177 228 ILEV--ADGVMVARGDLGIEVPQERIPGIQRTL--IRKCVLAKKPV-IVATQMLHTMINNPRPTRAEVTDI 293
Cdd:pfam03328 138 IAAVegVDGIFLGAEDLSADLGTLRSPGGPEVLyaRERIVTAARAAgIAAFDTVYSDENDAEGFLAEGALF 208
|
|
| |
