|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
2-319 |
0e+00 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 606.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 2 IKKIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSARFPEFRDEN 81
Cdd:PRK03202 1 MKRIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGGTILGSARFPEFKDEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 82 VRAKAIENLKNRGIDALVVIGGDGSYMGAKRLTEEGFPCIGLPGTIDNDVAGTDYTIGYFTALETVVEAIDRLRDTSSSH 161
Cdd:PRK03202 81 GRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEHGIPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAIDRLRDTASSH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 162 QRISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNREDLVCEIKAGIAKGKKHAIVAITEHICDIDELARHIEQETKR 241
Cdd:PRK03202 161 ERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEELCAKIKKGRERGKKHAIIVVAEGVMPAEELAKEIEERTGL 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 977432355 242 ETRATVLGHIQRGGSPVAYDRILASRMGAYAIELLLQGYGGRCVGIQNEKMVHHDIIDAIENMKRPFKGDWLETAKKL 319
Cdd:PRK03202 241 ETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGGRMVGIQNNKIVHVPIEEAVENMKHPFDKDLYELAKKL 318
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
3-320 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 561.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 3 KKIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSARFPEFRDENV 82
Cdd:cd00763 1 KRIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGDIVPLDRYSVSDIINRGGTFLGSARFPEFKDEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 83 RAKAIENLKNRGIDALVVIGGDGSYMGAKRLTEEGFPCIGLPGTIDNDVAGTDYTIGYFTALETVVEAIDRLRDTSSSHQ 162
Cdd:cd00763 81 QAKAIEQLKKHGIDALVVIGGDGSYMGAMRLTEHGFPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIRDTSSSHQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 163 RISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNREDLVCEIKAGIAKGKKHAIVAITEHICDIDELARHIEQETKRE 242
Cdd:cd00763 161 RISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREEVANRIKAGIERGKKHAIVVVAEGVYDVDELAKEIEEATGFE 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 977432355 243 TRATVLGHIQRGGSPVAYDRILASRMGAYAIELLLQGYGGRCVGIQNEKMVHHDIIDAIENMKrPFKGDWLETAKKLY 320
Cdd:cd00763 241 TRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLAGKGGLAVGIQNEQLVHHDIIDAIENMK-PFKKDWLALAKKLS 317
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
2-319 |
8.45e-167 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 467.24 E-value: 8.45e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 2 IKKIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSARFPEFRDEN 81
Cdd:COG0205 1 MKRIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGTILGSSRSKPFKTEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 82 VRAKAIENLKNRGIDALVVIGGDGSYMGAKRLTEE-GFPCIGLPGTIDNDVAGTDYTIGYFTALETVVEAIDRLRDTSSS 160
Cdd:COG0205 81 GREKALENLKKLGIDALVVIGGDGSLDGAAKLAEEyGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDRLRDTAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 161 HQRISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNREDLVCEIKAGIAKGKKHAIVAITEHICDID----------- 229
Cdd:COG0205 161 HERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKLLEKLKERRKRGKGYSIIVVAEGAGDEDgeavleadtda 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 230 -----------ELARHIEQETKRETRATVLGHIQRGGSPVAYDRILASRMGAYAIELLLQGYGGRCVGIQNEKMVHHDII 298
Cdd:COG0205 241 fghvrlggigeYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVGIRRGEIVLVPLE 320
|
330 340
....*....|....*....|..
gi 977432355 299 DAIENMKR-PFKGDWLETAKKL 319
Cdd:COG0205 321 EVANKEKPvDPDSPLIQLAREL 342
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
4-274 |
9.86e-158 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 441.39 E-value: 9.86e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 4 KIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSARFPEFRDENVR 83
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPFKTEEGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 84 AKAIENLKNRGIDALVVIGGDGSYMGAKRLTEE-GFPCIGLPGTIDNDVAGTDYTIGYFTALETVVEAIDRLRDTSSSHQ 162
Cdd:pfam00365 81 EKIAENLKKLGIDALVVIGGDGSLTGANKLSEErGIPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDTASSHN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 163 RISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNREDLVCEIKAGIaKGKKHAIVAITEHICDIDELARHIEQETKRE 242
Cdd:pfam00365 161 RVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKELR-KGKRFSIIVVAEGASDGEFLAKLIEEGTGIE 239
|
250 260 270
....*....|....*....|....*....|..
gi 977432355 243 TRATVLGHIQRGGSPVAYDRILASRMGAYAIE 274
Cdd:pfam00365 240 TRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| PFKA_ATP |
TIGR02482 |
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate ... |
4-301 |
2.90e-146 |
|
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate from ATP to fructose 6-phosphate to give fructose 1,6-bisphosphate. This represents a key control step in glycolysis. This model hits bacterial ATP-dependent 6-phosphofructokinases which lack a beta-hairpin loop present in TIGR02483 family members. TIGR02483 contains members that are ATP-dependent as well as members that are pyrophosphate-dependent. TIGR02477 represents the pyrophosphate-dependent phosphofructokinase, diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90). [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213713 [Multi-domain] Cd Length: 301 Bit Score: 413.67 E-value: 2.90e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 4 KIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSARFPEFRDENVR 83
Cdd:TIGR02482 1 KIGILTSGGDAPGMNAAIRAVVRTAIYHGFEVYGIRRGYKGLINGKIEPLESKNVSGIIHRGGTILGTARCPEFKTEEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 84 AKAIENLKNRGIDALVVIGGDGSYMGAKRLTEEG-FPCIGLPGTIDNDVAGTDYTIGYFTALETVVEAIDRLRDTSSSHQ 162
Cdd:TIGR02482 81 EKAVENLKKLGIEGLVVIGGDGSYTGAQKLYEEGgIPVIGLPGTIDNDIPGTDYTIGFDTALNTIIDAVDKIRDTATSHE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 163 RISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNREDLVCEIKAGIAKGKKHA-IVAITEHICD-IDELARHIEQETK 240
Cdd:TIGR02482 161 RAFVIEVMGRHAGDLALYAGIATGAEIIIIPEFDYDIDELIQRLKEQHEAGKKHSiIIVAEGNIVGsAKEVAKKIEEKTG 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 977432355 241 RETRATVLGHIQRGGSPVAYDRILASRMGAYAIELLLQGYGGRCVGIQNEKMVHHDIIDAI 301
Cdd:TIGR02482 241 IETRVTVLGHTQRGGSPSAFDRVLASRLGAKAVELLLEGKGGVMIGIQNNKIVTHPIEEAL 301
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
2-319 |
0e+00 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 606.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 2 IKKIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSARFPEFRDEN 81
Cdd:PRK03202 1 MKRIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGGTILGSARFPEFKDEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 82 VRAKAIENLKNRGIDALVVIGGDGSYMGAKRLTEEGFPCIGLPGTIDNDVAGTDYTIGYFTALETVVEAIDRLRDTSSSH 161
Cdd:PRK03202 81 GRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEHGIPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAIDRLRDTASSH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 162 QRISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNREDLVCEIKAGIAKGKKHAIVAITEHICDIDELARHIEQETKR 241
Cdd:PRK03202 161 ERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEELCAKIKKGRERGKKHAIIVVAEGVMPAEELAKEIEERTGL 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 977432355 242 ETRATVLGHIQRGGSPVAYDRILASRMGAYAIELLLQGYGGRCVGIQNEKMVHHDIIDAIENMKRPFKGDWLETAKKL 319
Cdd:PRK03202 241 ETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGGRMVGIQNNKIVHVPIEEAVENMKHPFDKDLYELAKKL 318
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
3-320 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 561.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 3 KKIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSARFPEFRDENV 82
Cdd:cd00763 1 KRIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGDIVPLDRYSVSDIINRGGTFLGSARFPEFKDEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 83 RAKAIENLKNRGIDALVVIGGDGSYMGAKRLTEEGFPCIGLPGTIDNDVAGTDYTIGYFTALETVVEAIDRLRDTSSSHQ 162
Cdd:cd00763 81 QAKAIEQLKKHGIDALVVIGGDGSYMGAMRLTEHGFPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIRDTSSSHQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 163 RISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNREDLVCEIKAGIAKGKKHAIVAITEHICDIDELARHIEQETKRE 242
Cdd:cd00763 161 RISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREEVANRIKAGIERGKKHAIVVVAEGVYDVDELAKEIEEATGFE 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 977432355 243 TRATVLGHIQRGGSPVAYDRILASRMGAYAIELLLQGYGGRCVGIQNEKMVHHDIIDAIENMKrPFKGDWLETAKKLY 320
Cdd:cd00763 241 TRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLAGKGGLAVGIQNEQLVHHDIIDAIENMK-PFKKDWLALAKKLS 317
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
2-319 |
8.45e-167 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 467.24 E-value: 8.45e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 2 IKKIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSARFPEFRDEN 81
Cdd:COG0205 1 MKRIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGTILGSSRSKPFKTEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 82 VRAKAIENLKNRGIDALVVIGGDGSYMGAKRLTEE-GFPCIGLPGTIDNDVAGTDYTIGYFTALETVVEAIDRLRDTSSS 160
Cdd:COG0205 81 GREKALENLKKLGIDALVVIGGDGSLDGAAKLAEEyGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDRLRDTAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 161 HQRISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNREDLVCEIKAGIAKGKKHAIVAITEHICDID----------- 229
Cdd:COG0205 161 HERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKLLEKLKERRKRGKGYSIIVVAEGAGDEDgeavleadtda 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 230 -----------ELARHIEQETKRETRATVLGHIQRGGSPVAYDRILASRMGAYAIELLLQGYGGRCVGIQNEKMVHHDII 298
Cdd:COG0205 241 fghvrlggigeYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVGIRRGEIVLVPLE 320
|
330 340
....*....|....*....|..
gi 977432355 299 DAIENMKR-PFKGDWLETAKKL 319
Cdd:COG0205 321 EVANKEKPvDPDSPLIQLAREL 342
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
3-318 |
9.20e-165 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 461.77 E-value: 9.20e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 3 KKIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSARFPEFRDENV 82
Cdd:cd00363 1 KKIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGTIIGSARCKEFRTEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 83 RAKAIENLKNRGIDALVVIGGDGSYMGAKRLTEE------GFPCIGLPGTIDNDVAGTDYTIGYFTALETVVEAIDRLRD 156
Cdd:cd00363 81 RAKAAENLKKHGIDALVVIGGDGSYTGADLLTEEwpskyqGFNVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIRD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 157 TSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEF---NREDLVCEIKAGIAKGKKHAIVAITEHICDI----- 228
Cdd:cd00363 161 TASSHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAadeWEEEMVDVIKKRRERGKRHGIVIVAEGAIDFipkpi 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 229 --DELARHIEQETKRETRATVLGHIQRGGSPVAYDRILASRMGAYAIELLLQGYGGRCVGIQNE---KMVHHDIIDAIEN 303
Cdd:cd00363 241 teKLLAKLVEERLGFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVELLLEGTGGTPVGIQNLnenQVVRHPLTEAVNM 320
|
330
....*....|....*...
gi 977432355 304 MKR---PFKGDWLETAKK 318
Cdd:cd00363 321 TKRvgvDLEGRPFKKFAK 338
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
4-274 |
9.86e-158 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 441.39 E-value: 9.86e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 4 KIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSARFPEFRDENVR 83
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPFKTEEGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 84 AKAIENLKNRGIDALVVIGGDGSYMGAKRLTEE-GFPCIGLPGTIDNDVAGTDYTIGYFTALETVVEAIDRLRDTSSSHQ 162
Cdd:pfam00365 81 EKIAENLKKLGIDALVVIGGDGSLTGANKLSEErGIPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDTASSHN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 163 RISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNREDLVCEIKAGIaKGKKHAIVAITEHICDIDELARHIEQETKRE 242
Cdd:pfam00365 161 RVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKELR-KGKRFSIIVVAEGASDGEFLAKLIEEGTGIE 239
|
250 260 270
....*....|....*....|....*....|..
gi 977432355 243 TRATVLGHIQRGGSPVAYDRILASRMGAYAIE 274
Cdd:pfam00365 240 TRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| PFKA_ATP |
TIGR02482 |
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate ... |
4-301 |
2.90e-146 |
|
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate from ATP to fructose 6-phosphate to give fructose 1,6-bisphosphate. This represents a key control step in glycolysis. This model hits bacterial ATP-dependent 6-phosphofructokinases which lack a beta-hairpin loop present in TIGR02483 family members. TIGR02483 contains members that are ATP-dependent as well as members that are pyrophosphate-dependent. TIGR02477 represents the pyrophosphate-dependent phosphofructokinase, diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90). [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213713 [Multi-domain] Cd Length: 301 Bit Score: 413.67 E-value: 2.90e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 4 KIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSARFPEFRDENVR 83
Cdd:TIGR02482 1 KIGILTSGGDAPGMNAAIRAVVRTAIYHGFEVYGIRRGYKGLINGKIEPLESKNVSGIIHRGGTILGTARCPEFKTEEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 84 AKAIENLKNRGIDALVVIGGDGSYMGAKRLTEEG-FPCIGLPGTIDNDVAGTDYTIGYFTALETVVEAIDRLRDTSSSHQ 162
Cdd:TIGR02482 81 EKAVENLKKLGIEGLVVIGGDGSYTGAQKLYEEGgIPVIGLPGTIDNDIPGTDYTIGFDTALNTIIDAVDKIRDTATSHE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 163 RISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNREDLVCEIKAGIAKGKKHA-IVAITEHICD-IDELARHIEQETK 240
Cdd:TIGR02482 161 RAFVIEVMGRHAGDLALYAGIATGAEIIIIPEFDYDIDELIQRLKEQHEAGKKHSiIIVAEGNIVGsAKEVAKKIEEKTG 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 977432355 241 RETRATVLGHIQRGGSPVAYDRILASRMGAYAIELLLQGYGGRCVGIQNEKMVHHDIIDAI 301
Cdd:TIGR02482 241 IETRVTVLGHTQRGGSPSAFDRVLASRLGAKAVELLLEGKGGVMIGIQNNKIVTHPIEEAL 301
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
3-305 |
1.21e-91 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 288.08 E-value: 1.21e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 3 KKIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYE--DRMEQLDRYSVSDMINRGGTFLGSARFPEFRDE 80
Cdd:TIGR02478 1 KRIAVLTSGGDAQGMNAAVRAVVRMAIYVGCRVYAIREGYQGLVDggDNIEEAQWEDVRGILSLGGTIIGTARCKEFRER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 81 NVRAKAIENLKNRGIDALVVIGGDGSYMGA-----------------KRLTEEG------FPCIGLPGTIDNDVAGTDYT 137
Cdd:TIGR02478 81 PGRLKAARNLVSNGIDALVVIGGDGSLTGAdlfreewpslleelvdtGKITAEQaeehrhLTIVGLVGSIDNDMCGTDMT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 138 IGYFTALETVVEAIDRLRDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEI---EFNREDLVCEIKAGIAKGK 214
Cdd:TIGR02478 161 IGADSALHRICEAIDAISSTAQSHQRAFVVEVMGRHCGYLALMAAIATGADYVFIPERppeEGWEDQLCHKLKRNRKAGK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 215 KHAIVAITEHIcdIDELARHI---------EQETKRETRATVLGHIQRGGSPVAYDRILASRMGAYAIELLLQGYG---G 282
Cdd:TIGR02478 241 RKTIVIVAEGA--IDRDLNPItsedvkdvlVERLGLDTRITVLGHVQRGGAPSAFDRILATRQGVEAVLAVLESTPetpS 318
|
330 340
....*....|....*....|...
gi 977432355 283 RCVGIQNEKMVHHDIIDAIENMK 305
Cdd:TIGR02478 319 PVISLRGNKIVRKPLVEAVAQTK 341
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
2-302 |
5.85e-83 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 255.00 E-value: 5.85e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 2 IKKIGVLTSGGDSPGMNAAIRGVVRSALSE-GLEVFGIYDGYLGLYED--RMEQLDRYSVSDMINRGGTFLGSAR----- 73
Cdd:PRK14071 4 KKRIGILTSGGDCAGLNAVIRAVVHRARGTyGWEVIGIRDATQGLMARppQYIELDLDQVDDLLRMGGTILGTTNkgdpf 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 74 -FP----EFRDENvrAKAIENLKNRGIDALVVIGGDGSYMGAKRLTEEG-FPCIGLPGTIDNDVAGTDYTIGYFTALETV 147
Cdd:PRK14071 84 aFPmpdgSLRDRS--QEIIDGYHSLGLDALIGIGGDGSLAILRRLAQQGgINLVGIPKTIDNDVGATEVSIGFDTAVNIA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 148 VEAIDRLRDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNREDLVCEIKAGIAKGKKHAIVAITEHICD 227
Cdd:PRK14071 162 TEALDRLHFTAASHNRVMILEVMGRDAGHIALAAGIAGGADVILIPEIPYTLENVCKKIRERQEEGKNFCLVVVSEAVRT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 228 ID--------------------ELARHIEQETKRETRATVLGHIQRGGSPVAYDRILASRMGAYAIELLLQGYGGRCVGI 287
Cdd:PRK14071 242 EEgeqvtktqalgedryggigqYLAEQIAERTGAETRVTVLGHIQRGGIPSPRDRLLASAFGVAAVDLIAQGKFDRMVAW 321
|
330
....*....|....*
gi 977432355 288 QNEKMVHHDIIDAIE 302
Cdd:PRK14071 322 QNRQVVSVPIAEAIA 336
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
3-279 |
4.47e-80 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 258.21 E-value: 4.47e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 3 KKIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYE--DRMEQLDRYSVSDMINRGGTFLGSARFPEFRDE 80
Cdd:cd00764 4 KAIAVLTSGGDAQGMNAAVRAVVRMGIYVGAKVFFVYEGYEGLVKggDYIKQAEWESVSNWLQEGGTIIGSARCKEFRER 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 81 NVRAKAIENLKNRGIDALVVIGGDGSYMGAK-----------------RLTEEGFP------CIGLPGTIDNDVAGTDYT 137
Cdd:cd00764 84 EGRLQAAYNLIQRGITNLCVIGGDGSLTGADlfrsewpslleelvkdgKITEEEVAkyqhlnIVGMVGSIDNDFCGTDMT 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 138 IGYFTALETVVEAIDRLRDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNR--EDLVCE-IKAGIAKGK 214
Cdd:cd00764 164 IGTDSALHRICEVVDAITTTAQSHQRTFVLEVMGRHCGYLALVSGLATGADWIFIPERPPEDgwEDQMCRrLSEHRSRGK 243
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 977432355 215 KHAIVAITEHIcdIDELARHIEQETKRE---------TRATVLGHIQRGGSPVAYDRILASRMGAYAIELLLQG 279
Cdd:cd00764 244 RLNIIIVAEGA--IDDQLKPITSEDVKDlvverlgldTRVTTLGHVQRGGTPSAFDRILASLMGVEAVMALLEA 315
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
3-277 |
5.90e-53 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 185.24 E-value: 5.90e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 3 KKIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSARFPEFRDENV 82
Cdd:TIGR02478 390 LRIAIIHVGAPAGGMNAATRSAVRYALARGHTVIAIHNGFSGLARHDVRELTWSDVEGWVGEGGSELGTNRSLPGDDLGT 469
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 83 RAKAIENLKnrgIDALVVIGGDGSYMGAKRLTE--EGFPC-----IGLPGTIDNDVAGTDYTIGYFTALETVVEAIDRLR 155
Cdd:TIGR02478 470 IAYYFQQHK---IDGLIIIGGFEAFEALYQLDAarEKYPAfripmVVIPATISNNVPGTEYSLGSDTALNEITEYCDNIK 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 156 DTSS-SHQRISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNREDL---VCEIKAGIAKGKKHAIVAITEHICDI--- 228
Cdd:TIGR02478 547 QSASaSKRRVFVVETMGGYSGYLATMAGLATGADAAYIPEEGISLKDLqedIEHLKETFAEGRAGKLILRNEKASKVytt 626
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 977432355 229 DELARHIEQETKR--ETRATVLGHIQRGGSPVAYDRILASRMGAYAIELLL 277
Cdd:TIGR02478 627 DFIARIISEEGKGrfDARTAVLGHMQQGGSPSPFDRVRATRLAIRAVDFIE 677
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
4-278 |
6.22e-42 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 154.60 E-value: 6.22e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 4 KIGVLTSGGDSPGMNAAIRGVVRSALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSARFPEFRDENVR 83
Cdd:cd00764 391 NIAIVNVGAPAAGMNAAVRSAVRYGLAHGHRPYAIYDGFEGLAKGQIVELGWIDVGGWTGRGGSELGTKRTLPKKDLETI 470
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 84 AkaiENLKNRGIDALVVIGGDGSYMGAKRLTE--EGFP--CIGL---PGTIDNDVAGTDYTIGYFTALETVVEAIDRLRD 156
Cdd:cd00764 471 A---YNFQKYGIDGLIIVGGFEAYKGLLQLREarEQYEefCIPMvliPATVSNNVPGTDFSLGSDTALNALMKYCDRIKQ 547
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 157 T-SSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEIEFNREDLVCEI-------KAGIAKGKKHAIVAITEHICD- 227
Cdd:cd00764 548 SaSGTKRRVFIVETMGGYCGYLATMTGLAVGADAAYVFEEPFNIRDLQENVehltekmKTTIGRGLVLRNEKCNENYTTv 627
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 977432355 228 -IDELARHiEQETKRETRATVLGHIQRGGSPVAYDRILASRMGAYAIELLLQ 278
Cdd:cd00764 628 fTYELYSE-EGKGVFDCRTNVLGHVQQGGAPSPFDRNFGTKFAVKAMKWIEQ 678
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
4-223 |
2.33e-39 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 144.03 E-value: 2.33e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 4 KIGVLTSGGDSPGMNAAIRGVVRSALSE-GLE-VFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSARFPEFRDEN 81
Cdd:PTZ00286 89 KAGIVTCGGLCPGLNVVIRELVMNLINNyGVKtIYGAKYGYKGLYKEDWIKLDPKDVKTIHRLGGTILGSSRGGFDPKVM 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 82 VrakaiENLKNRGIDALVVIGGDGSYMGAKRLTEE----GFPC--IGLPGTIDNDVAGTDYTIGYFTALETVVEAIDRLR 155
Cdd:PTZ00286 169 V-----DTLIRHGINILFTLGGDGTHRGALAIYKElrrrKLNIsvVGIPKTIDNDIPIIDESFGFQTAVEEAQNAIRAAY 243
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 156 DTSSSHQR-ISIVEVMGRYCGDLTLAAAIAGGCEFIVL-PEIEFNREDLVCEIKAGIAKgKKHAIVAITE 223
Cdd:PTZ00286 244 VEAKSAKNgVGIVKLMGRDSGFIALHASVASADVNVCLiPEFDIPLEGVLEYIEQRLQK-KGHCVIVVAE 312
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
1-288 |
4.40e-29 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 115.34 E-value: 4.40e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 1 MIKKIGVLTSGGDSPGMNAAIRGVVRSALS--EGLEVFGIYDGYLGLYEDR---MEQLDRYSVSDMINRGGTFLGSARFP 75
Cdd:PRK14072 2 MKGNALYAQSGGPTAVINASAAGVIEEARKhkKIGKVYGARNGIIGILDEDlidLSKESDEALAALAHTPSGALGSCRYK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 76 EFRDENVRA---KAIENLKNRGIDALVVIGGDGSYMGAKRLTEE----GFP--CIGLPGTIDNDVAGTDYTIGY-----F 141
Cdd:PRK14072 82 LKSLEEDRAeyeRLLEVFKAHDIGYFFYNGGNDSMDTALKVSQLakkmGYPirCIGIPKTIDNDLPGTDHCPGFgsaakY 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 142 TAlETVVEAIdrlRDTSSSHQ--RISIVEVMGRYCGDLTLAAAIA-----GGCEFIVLPEIEFNREDLVCEIKAGIAKGK 214
Cdd:PRK14072 162 IA-TSVLEAA---LDVAAMANtsKVFILEVMGRHAGWLAAAAALAkqnpdDAPHLIYLPERPFDEEKFLADVRAIVKRYG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 215 KHAIVA-----------ITEHICDIDE------------LARHIEQETKRETRATVLGHIQRGGSPVA--YDRILASRMG 269
Cdd:PRK14072 238 YCVVVVsegirdadgkfIAEAGLAEDAfghaqlggvapvLANLIKEKLGKKVHWAVLDYLQRAARHIAskTDVEEAYAVG 317
|
330
....*....|....*....
gi 977432355 270 AYAIELLLQGYGGRCVGIQ 288
Cdd:PRK14072 318 KAAVEYALAGKNGVMPAIR 336
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
7-197 |
6.12e-28 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 112.92 E-value: 6.12e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 7 VLTSGGDSPGMNAAIRGVVrSALSE--GL-EVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGGTFLGSArfpefRDENVR 83
Cdd:PLN02564 92 IVTCGGLCPGLNTVIREIV-CGLSYmyGVtRILGIDGGYRGFYSRNTIPLTPKVVNDIHKRGGTILGTS-----RGGHDT 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 84 AKAIENLKNRGIDALVVIGGDGSYMGAKRLTEE----GFPC--IGLPGTIDNDVAGTDYTIGYFTALETVVEAIDRLR-D 156
Cdd:PLN02564 166 SKIVDSIQDRGINQVYIIGGDGTQKGASVIYEEirrrGLKVavAGIPKTIDNDIPVIDKSFGFDTAVEEAQRAINAAHvE 245
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 977432355 157 TSSSHQRISIVEVMGRYCGDLTLAAAIAG---GCEFIvlPEIEF 197
Cdd:PLN02564 246 AESVENGIGLVKLMGRYSGFIAMYATLASrdvDCCLI--PESPF 287
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
4-306 |
8.69e-27 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 108.75 E-value: 8.69e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 4 KIGVLTSGGDSPGMNAAIRGVVRSALSEGLE-VFGIYDGYLGLYEDRMEQ--LDRYSVSDMINRGGTFLGSARfpefrDE 80
Cdd:PLN02884 55 KAAIVTCGGLCPGLNDVIRQIVFTLEIYGVKnIVGIPFGYRGFFEKGLSEmpLSRKVVQNIHLSGGSLLGVSR-----GG 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 81 NVRAKAIENLKNRGIDALVVIGGDGSYMGAKRLTEEgfpC---------IGLPGTIDNDVAGTDYTIGYFTALETVVEAI 151
Cdd:PLN02884 130 AKTSDIVDSIEARGINMLFVLGGNGTHAGANAIHNE---CrkrkmkvsvVGVPKTIDNDILLMDKTFGFDTAVEEAQRAI 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 152 DRLR-DTSSSHQRISIVEVMGRYCGDLTLAAAIAGG-CEFIVLPEIEFN---REDLVCEIKAGIAKgKKHAIVAITEHIC 226
Cdd:PLN02884 207 NSAYiEAHSAYHGIGLVKLMGRSSGFIAMHASLASGqVDICLIPEVPFTldgPNGVLRHLEHLIET-KGSAVVCVAEGAG 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 227 D----------------IDELARHIEQETKRetratvlgHIQRGGSPV-----------------AYDRILASRMGAYAI 273
Cdd:PLN02884 286 QdllqktnatdasgnpvLGDIGVHLQQEIKK--------HFKDIGVPAdvkyidptymiracranASDAILCTVLGQNAV 357
|
330 340 350
....*....|....*....|....*....|...
gi 977432355 274 ELLLQGYGGRCVGIQNEKMVHHDIIDAIENMKR 306
Cdd:PLN02884 358 HGAFAGFSGITVGICNTHYVYLPIPEVIAYPRR 390
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
4-197 |
1.70e-23 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 99.94 E-value: 1.70e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 4 KIGVLTSGGDSPGMNAAIRGVVRSALSE-GL-EVFGIYDGYLGL---YEDRMEQLDRYSVSDMINRGGTFLGSARFPEFR 78
Cdd:PRK06830 82 KAAIVTCGGLCPGLNDVIRAIVLELHHHyGVrRILGIRYGYQGLiprYGHDPVELTPEVVADIHEFGGTILGSSRGPQDP 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 79 DENVraKAIENLknrGIDALVVIGGDGSYMGAKRLTEE----GFP--CIGLPGTIDNDVAGTDYTIGYFTALETVVEAID 152
Cdd:PRK06830 162 EEIV--DTLERM---NINILFVIGGDGTLRGASAIAEEierrGLKisVIGIPKTIDNDINFIQKSFGFETAVEKATEAIR 236
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 977432355 153 rlrdtsSSHQR-------ISIVEVMGRYCGDLTLAAAIAGG-CEFIVLPEIEF 197
Cdd:PRK06830 237 ------CAHVEangapngIGLVKLMGRHSGFIAAYAALASKdVNFVLIPEVPF 283
|
|
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
3-228 |
7.09e-18 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 83.82 E-value: 7.09e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 3 KKIGVLTSGGDSPGMNAAIRGVVRS--ALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGG-TFLGSARFPEFRD 79
Cdd:PRK07085 71 LKVGVILSGGQAPGGHNVIAGLFDGlkKLNPDSKLFGFIGGPLGLLNGKYIEITEEVIDEYRNTGGfDMIGSGRTKIETE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 80 ENvRAKAIENLKNRGIDALVVIGGDGSYMGAKRLTE------EGFPCIGLPGTIDNDVAGT--DYTIGYFTALETVVEAI 151
Cdd:PRK07085 151 EQ-KEACLETVKKLKLDGLVIIGGDDSNTNAAILAEyfakhgCKTQVIGVPKTIDGDLKNEfiETSFGFDTATKTYSEMI 229
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 977432355 152 DRL-RDTSSSHQRISIVEVMGRYcgdltlAAAIAGGCEFIVLPEIEFNREdlvcEIKAgiakgKKHAIVAITEHICDI 228
Cdd:PRK07085 230 GNIsRDALSAKKYWHFIKLMGRS------ASHIALECALQTHPNICLISE----EVAE-----KKMSLQDIVHYIASV 292
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
1-200 |
9.03e-16 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 77.36 E-value: 9.03e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 1 MIKKIGVLTSGGDSPGMNAAIRGVVR--SALSEGLEVFGIYDGYLGLYEDRMEQLD---RYSVSDMINRGGTFLGSAR-- 73
Cdd:PRK06555 2 AVKKVALLTAGGLAPCLSSAVGGLIEryTEIAPEVEIIAYRSGYQGLLLGDSIEITpavRANAGLLHRYGGSPIGNSRvk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 74 FPEFRD----------ENVRAKAIENLKNRGIDALVVIGGDGSYMGA----KRLTEEGFP--CIGLPGTIDNDVAGTDYT 137
Cdd:PRK06555 82 LTNVADcvkrglvkegENPLKVAAERLAADGVDILHTIGGDDTNTTAadlaAYLAENGYDltVVGLPKTIDNDVVPIRQS 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 977432355 138 IGYFTALETVVEAIDRLRDTSSSHQRISIV-EVMGRYCGDLTLAAAIA-----GGCEFivLPEIEFNRE 200
Cdd:PRK06555 162 LGAWTAAEQGARFFDNVINEHSANPRMLIIhEVMGRNCGWLTAATARAyrewlDRQEY--VPGFGLSAE 228
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
3-223 |
1.29e-15 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 77.71 E-value: 1.29e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 3 KKIGVLTSGGDSPGMNAAIRGVVR--SALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGG-TFLGSARFPEFRD 79
Cdd:PTZ00468 103 RRIGVVLSGGQASGGHNVIAGLMSyiKLCNQSSQLFGFLGGPEGVYSERYRELTEDDINGILNQGGfNIICSGRHKIETE 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 80 ENVRA--KAIENLKNRGidaLVVIGGDGSYMGAKRLTE------EGFPCIGLPGTIDNDVAG--TDYTIGYFTALETVVE 149
Cdd:PTZ00468 183 EQMRAslEICEKLKLHG---LVVIGGDDSNTNAAVLAEyfkrnsSSTVVVGCPKTIDGDLKNevIETSFGYDTAVKTYSE 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 150 AIDRLRDT-SSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIVLPE--IEFNRE--DLVCEIKAGIAK----GKKHAIVA 220
Cdd:PTZ00468 260 QIGSIMDAiKTEGYGYYFVRLMGRSASHITLECGLQTRANMILIGEeiKEENRSlmSIVDEIVEMILKrdslGKKHGIVL 339
|
...
gi 977432355 221 ITE 223
Cdd:PTZ00468 340 LPE 342
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
2-202 |
3.15e-15 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 76.62 E-value: 3.15e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 2 IKKIGVLTSGGDSPGMNAAIRGVVRSA--LSEGLEVFGIYDGYLGLYEDrmeqlDRYSVSD-MINR-----GGTFLGSAR 73
Cdd:PTZ00287 177 VLKIGIILSGGPAPGGHNVISGIYDYAkrYNEQSQVIGFLGGIDGLYSK-----NYVTITDsLMNRfrnlgGFNMLWSGR 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 74 fpefrdENVRAK----AIENLKNR-GIDALVVIGGDGSYMGAKRLT----EEGFP--CIGLPGTIDNDVA--GTDYTIGY 140
Cdd:PTZ00287 252 ------GKVRNKddliAIENIVAKlKLNGLVIIGGDGSNSNAALISeyfaERQIPisIIGIPKTIDGDLKseAIEISFGF 325
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 977432355 141 FTALETVVEAIDRL-RDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIVLPEiEFNREDL 202
Cdd:PTZ00287 326 DTATKTYSEVIGNLcTDVKTGHNVYHVVRVMGRSASHVVLECALQTRPNIVLIGE-EVEKENL 387
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
4-183 |
3.37e-13 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 69.90 E-value: 3.37e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 4 KIGVLTSGGDSPGMNAAIRGVVrSALSE---GLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGG-TFLGSARfPEFRD 79
Cdd:cd00765 74 KIGIVLSGGQAPGGHNVISGLF-DYLKErakGSTLYGFKGGPAGILKCDYIELNAEYIQPYRNTGGfDMICSGR-TKIET 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 80 ENVRAKAIENLKNRGIDALVVIGGDGSYMGAKRLTE------EGFPCIGLPGTIDNDVAG--TDYTIGYFTALETVVEAI 151
Cdd:cd00765 152 EDQFKQAEETAKKLDLDALVVIGGDDSNTNAALLAEnfrskgLKTRVIGVPKTIDGDLKNkeIETSFGFDTATKIYSELI 231
|
170 180 190
....*....|....*....|....*....|...
gi 977432355 152 DRL-RDTSSSHQRISIVEVMGRYCGDLTLAAAI 183
Cdd:cd00765 232 GNVmRDARSTGKYWHFVKLMGRSASHIALECAL 264
|
|
| PLN02251 |
PLN02251 |
pyrophosphate-dependent phosphofructokinase |
4-183 |
9.20e-08 |
|
pyrophosphate-dependent phosphofructokinase
Pssm-ID: 215140 Cd Length: 568 Bit Score: 53.26 E-value: 9.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 4 KIGVLTSGGDSPGMNAAIRGVVR--SALSEGLEVFGIYDGYLGLYEDRMEQLDRYSVSDMINRGG-TFLGSAR----FPE 76
Cdd:PLN02251 98 KIGVVLSGGQAPGGHNVISGIFDylQEHAKGSVLYGFKGGPAGIMKCKYVELTAEFIYPYRNQGGfDMICSGRdkieTPE 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 77 -FRdenvraKAIENLKNRGIDALVVIGGDGSYMGAKRLTE----EGFPC--IGLPGTIDNDVAGTDYTI--GYFTALETV 147
Cdd:PLN02251 178 qFK------QAEETATKLDLDGLVVIGGDDSNTNACLLAEyfraKNLKTrvIGCPKTIDGDLKSKEVPTsfGFDTACKIY 251
|
170 180 190
....*....|....*....|....*....|....*..
gi 977432355 148 VEAI-DRLRDTSSSHQRISIVEVMGRYCGDLTLAAAI 183
Cdd:PLN02251 252 SEMIgNVMIDARSTGKYYHFVRLMGRAASHITLECAL 288
|
|
| PLN03028 |
PLN03028 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
4-223 |
5.04e-05 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 215543 Cd Length: 610 Bit Score: 44.77 E-value: 5.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 4 KIGVLTSGGDSPGMNAAIRGvvrsaLSEGLEV-------FGIYDGYLGLYEDRMEQLDRYSVSDMINRGG-TFLGSARFP 75
Cdd:PLN03028 81 RVGVVFCGRQSPGGHNVIWG-----LHDALKAhnpnsvlLGFLGGTEGLFAQKTLEITDDVLSTYKNQGGyDLLGRTKDQ 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 76 EFRDENVRA--KAIENLKnrgIDALVVIGGDGSYMGAKRLTEEgFP---C----IGLPGTIDNDVAG--TDYTIGYFTAL 144
Cdd:PLN03028 156 IRTTEQVNAalAACEALK---LDGLVIIGGVTSNTDAAQLAET-FAeakCktkvVGVPVTLNGDLKNqfVETNVGFDTIC 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977432355 145 ETVVEAIDRL-RDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIVL-PEIEFNREDL------VCE-IKAGIAKGKK 215
Cdd:PLN03028 232 KVNSQLISNVcTDALSAEKYYYFIRLMGRKASHVALECALQSHPNMVILgEEVAASKLTLfditkqICDaVQARAEQDKN 311
|
....*...
gi 977432355 216 HAIVAITE 223
Cdd:PLN03028 312 HGVILIPE 319
|
|
| |
