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Conserved domains on  [gi|977171792|emb|CVG39304|]
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Phosphatidylglycerophosphatase B [Serratia marcescens]

Protein Classification

phosphatidylglycerophosphatase B( domain architecture ID 10013608)

phosphatidylglycerophosphatase B catalyzes the dephosphorylation of diacylglycerol diphosphate (DGPP) to phosphatidate (PA) and the subsequent dephosphorylation of PA to diacylglycerol (DAG); also has undecaprenyl pyrophosphate phosphatase activity, required for the biosynthesis of the lipid carrier undecaprenyl phosphate; can also use lysophosphatidic acid (LPA) and phosphatidylglycerophosphate as substrates

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10699 PRK10699
phosphatidylglycerophosphatase B; Provisional
 1-244 4.95e-138

phosphatidylglycerophosphatase B; Provisional


:

Pssm-ID: 182658  Cd Length: 244  Bit Score: 387.85  E-value: 4.95e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792   1 MYEIAKRTAGGALLLLLMPLAVWVSGWHWQPGGNEPLLKALYWVTETVTSPWGILTSAILCGWFLWCLRFRLKAAIGLAL 80
Cdd:PRK10699   1 MYSIAKRTAVGAALLLVMPLAVWISGWQWQPGEQSWWLKGLFWVTETVTQPWGILTHVLLCGWFLWCLRFRLKAALVLFA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792  81 LLFAALVIGQGVKSLIKDRVQEPRPFVVWLEQTHGVDGKYFYSLHRKERSALVREQLQDQTLVPNWLRKHWQFETGFAFP 160
Cdd:PRK10699  81 ILAAAILVGQGVKSWIKERVQEPRPFVVWLEKTHHIPVDEFYTLKRAERGELVKEQLAEQSNIPQWLRSHWQKETGFAFP 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792 161 SGHTMFAATWALLGVGLLWPRRHYKTVALLMVWATGVMGSRLLLGMHWPRDLAMATLISWLLVVVTCWLAQRWFGPLTPP 240
Cdd:PRK10699 161 SGHTMFAASWALLAVGLLWPRRRYKTVALLMLWATGVMGSRLLLGMHWPRDLVVATLISWLLVTVATWLAQRICGPLTPP 240


                 ....
gi 977171792 241 PQEQ 244
Cdd:PRK10699 241 PEEN 244
 
Name Accession Description Interval E-value
PRK10699 PRK10699
phosphatidylglycerophosphatase B; Provisional
 1-244 4.95e-138

phosphatidylglycerophosphatase B; Provisional


Pssm-ID: 182658  Cd Length: 244  Bit Score: 387.85  E-value: 4.95e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792   1 MYEIAKRTAGGALLLLLMPLAVWVSGWHWQPGGNEPLLKALYWVTETVTSPWGILTSAILCGWFLWCLRFRLKAAIGLAL 80
Cdd:PRK10699   1 MYSIAKRTAVGAALLLVMPLAVWISGWQWQPGEQSWWLKGLFWVTETVTQPWGILTHVLLCGWFLWCLRFRLKAALVLFA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792  81 LLFAALVIGQGVKSLIKDRVQEPRPFVVWLEQTHGVDGKYFYSLHRKERSALVREQLQDQTLVPNWLRKHWQFETGFAFP 160
Cdd:PRK10699  81 ILAAAILVGQGVKSWIKERVQEPRPFVVWLEKTHHIPVDEFYTLKRAERGELVKEQLAEQSNIPQWLRSHWQKETGFAFP 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792 161 SGHTMFAATWALLGVGLLWPRRHYKTVALLMVWATGVMGSRLLLGMHWPRDLAMATLISWLLVVVTCWLAQRWFGPLTPP 240
Cdd:PRK10699 161 SGHTMFAASWALLAVGLLWPRRRYKTVALLMLWATGVMGSRLLLGMHWPRDLVVATLISWLLVTVATWLAQRICGPLTPP 240


                 ....
gi 977171792 241 PQEQ 244
Cdd:PRK10699 241 PEEN 244
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 87-232 9.18e-18

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 76.69  E-value: 9.18e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792   87 VIGQGVKSLIKDRVQEPRPFVVWLEQTHGVDGKYFYSLHRKersalvreqlqdqtlvpnwlrkhwqfetgfaFPSGHTMF 166
Cdd:pfam01569   7 ALAGLLSSVLKDYFGRPRPFFLLLEGGLVPAPSTLPGLGYS-------------------------------FPSGHSAT 55

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 977171792  167 AATWALLGVGLLWPRRHYKTV---ALLMVWATGVMGSRLLLGMHWPRDLAMATLISWLLVVVTCWLAQR 232
Cdd:pfam01569  56 AFALALLLALLLRRLRKIVRVllaLLLLVLALLVGLSRLYLGVHFPSDVLAGALIGILLALLVYRLVPK 124
acidPPc smart00014
Acid phosphatase homologues;
87-227 1.80e-17

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 75.85  E-value: 1.80e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792    87 VIGQGVKSLIKDRVQEPRPFVVWLeqthgvdgkyfyslhrkersalvreqlqdqTLVPNWLRKHWQFETGFAFPSGHTMF 166
Cdd:smart00014   5 VVSQLFNGVIKNYFGRPRPFFLSI------------------------------GDACCTPNFLLTLEAGYSFPSGHTAF 54

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 977171792   167 AATWALLGVGLLWPR-RHYKTVALLMVWATGVMGSRLLLGMHWPRDLAMATLISWLLVVVTC 227
Cdd:smart00014  55 AFAFALFLLLYLPARaGRKLLIFLLLLLALVVGFSRVYLGAHWPSDVLAGSLLGILIAAVLF 116
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 18-232 4.59e-15

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 71.22  E-value: 4.59e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792  18 MPLAVWVSGWHWQPGGNEPLLKALYWVTETVTSPWGILTSAILCGWFLWCLRFRLKAAIGLALLLFAALVIGQGVKSLIK 97
Cdd:COG0671   14 LLLADLLALALLALLLLLALLLLLLLLLALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAALLLLLLLLLLLLLK 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792  98 DRVQEPRPFVVWLeqthgvdgkyfyslhrkersalvreqlqdqtlvpnwLRKHWQFETGFAFPSGHTMFAATWALLgVGL 177
Cdd:COG0671   94 YLFGRPRPFVVPD------------------------------------LELLLGTAGGYSFPSGHAAAAFALALV-LAL 136

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 977171792 178 LWPRRHYktVALLMVWATGVMGSRLLLGMHWPRDLAMATLISWLLVVVTCWLAQR 232
Cdd:COG0671  137 LLPRRWL--AALLLALALLVGLSRVYLGVHYPSDVLAGALLGLAIALLLLALLRR 189
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 141-226 7.32e-12

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 60.94  E-value: 7.32e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792 141 TLVPNWLRKHWQFETGFAFPSGHTMFAATWALLGVGLLWPRRHYKTV-ALLMVWATGVMGSRLLLGMHWPRDLAMATLIS 219
Cdd:cd01610   35 LRCGPDGDPLLLTEGGYSFPSGHAAFAFALALFLALLLPRRLLRLLLgLLLLLLALLVGLSRVYLGVHYPSDVLAGALLG 114


                 ....*..
gi 977171792 220 WLLVVVT 226
Cdd:cd01610  115 ILVALLV 121
 
Name Accession Description Interval E-value
PRK10699 PRK10699
phosphatidylglycerophosphatase B; Provisional
 1-244 4.95e-138

phosphatidylglycerophosphatase B; Provisional


Pssm-ID: 182658  Cd Length: 244  Bit Score: 387.85  E-value: 4.95e-138
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792   1 MYEIAKRTAGGALLLLLMPLAVWVSGWHWQPGGNEPLLKALYWVTETVTSPWGILTSAILCGWFLWCLRFRLKAAIGLAL 80
Cdd:PRK10699   1 MYSIAKRTAVGAALLLVMPLAVWISGWQWQPGEQSWWLKGLFWVTETVTQPWGILTHVLLCGWFLWCLRFRLKAALVLFA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792  81 LLFAALVIGQGVKSLIKDRVQEPRPFVVWLEQTHGVDGKYFYSLHRKERSALVREQLQDQTLVPNWLRKHWQFETGFAFP 160
Cdd:PRK10699  81 ILAAAILVGQGVKSWIKERVQEPRPFVVWLEKTHHIPVDEFYTLKRAERGELVKEQLAEQSNIPQWLRSHWQKETGFAFP 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792 161 SGHTMFAATWALLGVGLLWPRRHYKTVALLMVWATGVMGSRLLLGMHWPRDLAMATLISWLLVVVTCWLAQRWFGPLTPP 240
Cdd:PRK10699 161 SGHTMFAASWALLAVGLLWPRRRYKTVALLMLWATGVMGSRLLLGMHWPRDLVVATLISWLLVTVATWLAQRICGPLTPP 240


                 ....
gi 977171792 241 PQEQ 244
Cdd:PRK10699 241 PEEN 244
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 87-232 9.18e-18

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 76.69  E-value: 9.18e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792   87 VIGQGVKSLIKDRVQEPRPFVVWLEQTHGVDGKYFYSLHRKersalvreqlqdqtlvpnwlrkhwqfetgfaFPSGHTMF 166
Cdd:pfam01569   7 ALAGLLSSVLKDYFGRPRPFFLLLEGGLVPAPSTLPGLGYS-------------------------------FPSGHSAT 55

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 977171792  167 AATWALLGVGLLWPRRHYKTV---ALLMVWATGVMGSRLLLGMHWPRDLAMATLISWLLVVVTCWLAQR 232
Cdd:pfam01569  56 AFALALLLALLLRRLRKIVRVllaLLLLVLALLVGLSRLYLGVHFPSDVLAGALIGILLALLVYRLVPK 124
acidPPc smart00014
Acid phosphatase homologues;
87-227 1.80e-17

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 75.85  E-value: 1.80e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792    87 VIGQGVKSLIKDRVQEPRPFVVWLeqthgvdgkyfyslhrkersalvreqlqdqTLVPNWLRKHWQFETGFAFPSGHTMF 166
Cdd:smart00014   5 VVSQLFNGVIKNYFGRPRPFFLSI------------------------------GDACCTPNFLLTLEAGYSFPSGHTAF 54

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 977171792   167 AATWALLGVGLLWPR-RHYKTVALLMVWATGVMGSRLLLGMHWPRDLAMATLISWLLVVVTC 227
Cdd:smart00014  55 AFAFALFLLLYLPARaGRKLLIFLLLLLALVVGFSRVYLGAHWPSDVLAGSLLGILIAAVLF 116
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 18-232 4.59e-15

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 71.22  E-value: 4.59e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792  18 MPLAVWVSGWHWQPGGNEPLLKALYWVTETVTSPWGILTSAILCGWFLWCLRFRLKAAIGLALLLFAALVIGQGVKSLIK 97
Cdd:COG0671   14 LLLADLLALALLALLLLLALLLLLLLLLALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAALLLLLLLLLLLLLK 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792  98 DRVQEPRPFVVWLeqthgvdgkyfyslhrkersalvreqlqdqtlvpnwLRKHWQFETGFAFPSGHTMFAATWALLgVGL 177
Cdd:COG0671   94 YLFGRPRPFVVPD------------------------------------LELLLGTAGGYSFPSGHAAAAFALALV-LAL 136

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 977171792 178 LWPRRHYktVALLMVWATGVMGSRLLLGMHWPRDLAMATLISWLLVVVTCWLAQR 232
Cdd:COG0671  137 LLPRRWL--AALLLALALLVGLSRVYLGVHYPSDVLAGALLGLAIALLLLALLRR 189
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 141-226 7.32e-12

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 60.94  E-value: 7.32e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792 141 TLVPNWLRKHWQFETGFAFPSGHTMFAATWALLGVGLLWPRRHYKTV-ALLMVWATGVMGSRLLLGMHWPRDLAMATLIS 219
Cdd:cd01610   35 LRCGPDGDPLLLTEGGYSFPSGHAAFAFALALFLALLLPRRLLRLLLgLLLLLLALLVGLSRVYLGVHYPSDVLAGALLG 114


                 ....*..
gi 977171792 220 WLLVVVT 226
Cdd:cd01610  115 ILVALLV 121
PAP2_like_2 cd03392
PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 150-233 6.98e-11

PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239486  Cd Length: 182  Bit Score: 59.54  E-value: 6.98e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792 150 HWQFETGFAFPSGHTMFAATWALLGVGLLWPRRHYKT-----VALLMVWATGVMGSRLLLGMHWPRDLAMATLISWLLVV 224
Cdd:cd03392   94 LLVPEGGYSFPSGHAMGATVLYGFLAYLLARRLPRRRvrillLILAAILILLVGLSRLYLGVHYPSDVLAGWLLGLAWLA 173


                 ....*....
gi 977171792 225 VTCWLAQRW 233
Cdd:cd03392  174 LLILLYRRL 182
PAP2_SPPase1 cd03388
PAP2_like proteins, sphingosine-1-phosphatase subfamily. Sphingosine-1-phosphatase is an ...
 144-231 1.09e-07

PAP2_like proteins, sphingosine-1-phosphatase subfamily. Sphingosine-1-phosphatase is an intracellular enzyme located in the endoplasmic reticulum, which regulates the level of sphingosine-1-phosphate (S1P), a bioactive lipid. S1P acts as a second messenger in the cell, and extracellularly by binding to G-protein coupled receptors of the endothelial differentiation gene family.


Pssm-ID: 239482  Cd Length: 151  Bit Score: 49.92  E-value: 1.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792 144 PNWLRKHWQFETGFAFPSGHTMFAATWALLGVGLLWPRRHYKTVALLM---VWATGVMGSRLLLGMHWPRDlamatLISW 220
Cdd:cd03388   65 PVVRLTMSSAALEYGFPSTHAMNATAISFYLLIYLYDRYQYPFVLGLIlalFYSTLVCLSRIYMGMHSVLD-----VIAG 139

                         90
                 ....*....|.
gi 977171792 221 LLVVVTCWLAQ 231
Cdd:cd03388  140 SLIGVLILLFR 150
PAP2_acid_phosphatase cd03397
PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes ...
 155-212 1.61e-06

PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains to be determined.


Pssm-ID: 239491  Cd Length: 232  Bit Score: 47.72  E-value: 1.61e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 977171792 155 TGFAFPSGHTMFAATWALLGVGLLwPRRHyktVALLMvwATGVMG-SRLLLGMHWPRDL 212
Cdd:cd03397  148 KDGSYPSGHTAAGYAWALILAELV-PERA---DEILA--RGSEYGqSRIVCGVHWPSDV 200
PAP2_BcrC_like cd03385
PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as ...
 159-232 2.70e-06

PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from Bacillus subtilis posesses undecaprenyl pyrophosphate (UPP) phospatase activity, and it is hypothesized that it competes with bacitracin for UPP, increasing the cell's resistance to bacitracin.


Pssm-ID: 239480  Cd Length: 144  Bit Score: 45.71  E-value: 2.70e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 977171792 159 FPSGHT--MFAATWALLgvglLWPRRhyKTVALLMVWATGVMGSRLLLGMHWPRDLAMATLISwllvVVTCWLAQR 232
Cdd:cd03385   79 FPSDHTtlFFSIAFSLL----LRRRK--WAGWILLILALLVAWSRIYLGVHYPLDMLGAALVA----VLSALLVFQ 144
PAP2_like_6 cd03396
PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 139-234 1.01e-05

PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239490  Cd Length: 197  Bit Score: 44.98  E-value: 1.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792 139 DQTLVPNWLRKHWQFETGFAFPSGHTMFAATWALLGVGLLWPRRHYKTVALLMVWATG-VMG-SRLLLGMHWPRDlamaT 216
Cdd:cd03396  104 DAPYTPLFSGPSNGCGKGCSFPSGHASAGFALLALYFLFRRRRPRLARLVLAAGLALGaLMGlARMARGAHFLSD----V 179

                         90
                 ....*....|....*...
gi 977171792 217 LISWLLVVVTCWLAQRWF 234
Cdd:cd03396  180 LWSLLLVWLIALLLYRLI 197
PAP2_like_3 cd03393
PAP2_like_3 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 156-224 1.10e-04

PAP2_like_3 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria and archaea, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239487 [Multi-domain]  Cd Length: 125  Bit Score: 40.82  E-value: 1.10e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792 156 GFAFPSGHTMFAAT-WALLGVglLWPRRHYKTVALLMVwaTGVMGSRLLLGMHWPRDLAMATLISWLLVV 224
Cdd:cd03393   57 GYGFPSGHAQTSATfWGSLML--HVRKKWFTLIGVVLV--VLISFSRLYLGVHWPSDVIGGVLIGLLVLV 122
PAP2_like_1 cd03380
PAP2_like_1 proteins, a sub-family of PAP2, containing bacterial acid phosphatase, vanadium ...
 158-218 3.74e-04

PAP2_like_1 proteins, a sub-family of PAP2, containing bacterial acid phosphatase, vanadium chloroperoxidases and vanadium bromoperoxidases.


Pssm-ID: 239475  Cd Length: 209  Bit Score: 40.49  E-value: 3.74e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 977171792 158 AFPSGHTMFAATWALLGVGLLwprrHYKTVALLMvwATGVMG-SRLLLGMHWPRDLAMATLI 218
Cdd:cd03380  144 SYPSGHATFGGAAALVLAELF----PERAAELLA--RAAEAGnSRVVAGVHWPSDVEAGRIL 199
PAP2_lipid_A_1_phosphatase cd03389
PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from ...
 149-226 5.69e-04

PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from Francisella novicida selectively dephosphorylates lipid A at the 1-position. Lipid A is the membrane-anchor component of lipopolysaccharides (LPS), the major constituents of the outer membrane in many gram-negative bacteria.


Pssm-ID: 239483  Cd Length: 186  Bit Score: 39.61  E-value: 5.69e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792 149 KHWQFETGFA-FPSGH--TMFAATWALlgvGLLWPRRHYKTVALLMVwatgVMGSRLLLGMHWPRDLAMATLISWLLVVV 225
Cdd:cd03389  109 DPFHADYAFTsFPSGHsaTAGAAAAAL---ALLFPRYRWAFILLALL----IAFSRVIVGAHYPSDVIAGSLLGAVTALA 181


                 .
gi 977171792 226 T 226
Cdd:cd03389  182 L 182
PAP2_like_4 cd03395
PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 156-231 3.20e-03

PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239489  Cd Length: 177  Bit Score: 37.24  E-value: 3.20e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 977171792 156 GFAFPSGHTMFAATWALLgVGLLWPRRHYKTVALLmvWATGVMGSRLLLGMHWPRDLAMATLISWLLVVVTCWLAQ 231
Cdd:cd03395  103 SYSFASSHAANSFALALF-IWLFFRRGLFSPVLLL--WALLVGYSRVYVGVHYPGDVIAGALIGIISGLLFYLLFS 175
PRK11837 PRK11837
undecaprenyl pyrophosphate phosphatase; Provisional
 159-236 3.46e-03

undecaprenyl pyrophosphate phosphatase; Provisional


Pssm-ID: 183335  Cd Length: 202  Bit Score: 37.68  E-value: 3.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792 159 FPSGHTMFAATWALlgVGLLWPRRhyKTVALLMVWATGVMGSRLLLGMHWPRDLAMATLISwllvVVTCWLAQ---RWFG 235
Cdd:PRK11837 105 FPSDHGTVIFTFAL--AFLFWHRL--WSGSLLMAIAVAIAWSRVYLGVHWPLDMLGALLVG----MIGCLSAQiiwQLFG 176


                 .
gi 977171792 236 P 236
Cdd:PRK11837 177 E 177
PAP2_like_5 cd03394
PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 159-223 6.56e-03

PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239488 [Multi-domain]  Cd Length: 106  Bit Score: 35.38  E-value: 6.56e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 977171792 159 FPSGHTmfaaTWALLGVGLLWPRRHYKTVAL-LMVWATGVMGSRLLLGMHWPRDL----AMATLISWLLV 223
Cdd:cd03394   41 FPSGHT----ASAFAAATFLQYRYGWRWYGIpAYALASLVGASRVVANRHWLSDVlagaAIGILVGYLVT 106
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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