|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08610 |
PRK08610 |
fructose-bisphosphate aldolase; Reviewed |
1-286 |
0e+00 |
|
fructose-bisphosphate aldolase; Reviewed
Pssm-ID: 181501 Cd Length: 286 Bit Score: 608.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTIVKMVEGLMHDLNITIPV 80
Cdd:PRK08610 1 MPLVSMKEMLIDAKENGYAVGQYNLNNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTVVKMVEGLMHDLNITIPV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKE 160
Cdd:PRK08610 81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 161 CQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIAS 240
Cdd:PRK08610 161 CQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIAS 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 996413163 241 AKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRAK 286
Cdd:PRK08610 241 AKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRAK 286
|
|
| fruc_bis_ald_ |
TIGR01859 |
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; ... |
3-285 |
5.80e-161 |
|
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 130918 Cd Length: 282 Bit Score: 448.73 E-value: 5.80e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 3 LVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTIVKMVEGLMHDLNItIPVAI 82
Cdd:TIGR01859 1 LVNGKEILQKAKKEGYAVGAFNFNNLEWTQAILEAAEEENSPVIIQVSEGAIKYMGGYKMAVAMVKTLIERMSI-VPVAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 83 HLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKECQ 162
Cdd:TIGR01859 80 HLDHGSSYESCIKAIKAGFSSVMIDGSHLPFEENLALTKKVVEIAHAKGVSVEAELGTLGGIEDGVDEKEAELADPDEAE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 163 ELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAK 242
Cdd:TIGR01859 160 QFVKETGVDYLAAAIGTSHGKYKGEPGLDFERLKEIKELTNIPLVLHGASGIPEEQIKKAIKLGIAKINIDTDCRIAFTA 239
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 996413163 243 AVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:TIGR01859 240 AIRKVLTEKKDEYDPRKILGPAREAIKETVKEKMRLFGSAGKA 282
|
|
| Fba |
COG0191 |
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ... |
2-285 |
2.05e-153 |
|
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439961 Cd Length: 283 Bit Score: 429.51 E-value: 2.05e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 2 PLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMsGFYTIVKMVEGLMHdlNITIPVA 81
Cdd:COG0191 1 MLVSLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYA-GLEYLAAMVRAAAE--EASVPVA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 82 IHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVV--ADGIIYADPK 159
Cdd:COG0191 78 LHLDHGASFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEEDGVDvdDAEALYTDPE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 160 ECQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIA 239
Cdd:COG0191 158 EAAEFVEETGVDALAVAIGTVHGVYKGEPKLDFDRLKEIREAVPVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLA 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 996413163 240 SAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:COG0191 238 FTAAVREYLAENPDKYDPRKYLKPAREAMKEVVKEKIRLFGSAGKA 283
|
|
| TBP_aldolase_IIB |
cd00947 |
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ... |
6-283 |
2.55e-144 |
|
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.
Pssm-ID: 238477 Cd Length: 276 Bit Score: 406.14 E-value: 2.55e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 6 MKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMsGFYTIVKMVEGLMHDLniTIPVAIHLD 85
Cdd:cd00947 1 TKELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYA-GLELLVAMVKAAAERA--SVPVALHLD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 86 HGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKECQELV 165
Cdd:cd00947 78 HGSSFELIKRAIRAGFSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVGDEGLLTDPEEAEEFV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 166 EKTGIDALAPALGSVHGPYKG-EPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAKAV 244
Cdd:cd00947 158 EETGVDALAVAIGTSHGAYKGgEPKLDFDRLKEIAERVNVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAAL 237
|
250 260 270
....*....|....*....|....*....|....*....
gi 996413163 245 RDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSN 283
Cdd:cd00947 238 REYLAENPKEFDPRKYLAPAIEAVKEVVKHKMELFGSAG 276
|
|
| F_bP_aldolase |
pfam01116 |
Fructose-bisphosphate aldolase class-II; |
4-284 |
1.04e-143 |
|
Fructose-bisphosphate aldolase class-II;
Pssm-ID: 460071 Cd Length: 276 Bit Score: 404.87 E-value: 1.04e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 4 VSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAAR-YMSGFYTIVKMVEGLMHDLNItiPVAI 82
Cdd:pfam01116 1 VNLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAkYAGGAEALAALVRAAAEAAGV--PVAL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 83 HLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKECQ 162
Cdd:pfam01116 79 HLDHGASFELIKEAIEAGFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIGGEEDGVVVDEKLYTDPEEAA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 163 ELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAK 242
Cdd:pfam01116 159 EFVEATGVDALAVAIGNVHGVYKPGPKLDFDRLKEIQEAVPVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTA 238
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 996413163 243 AVRDVLNNdkevYDPRKYLGPAREAIKETVKGKIKEFGTSNR 284
Cdd:pfam01116 239 AVREYPPN----KDPRKYLRPAEEAMKEVVKEKIRLFGSAGK 276
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08610 |
PRK08610 |
fructose-bisphosphate aldolase; Reviewed |
1-286 |
0e+00 |
|
fructose-bisphosphate aldolase; Reviewed
Pssm-ID: 181501 Cd Length: 286 Bit Score: 608.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTIVKMVEGLMHDLNITIPV 80
Cdd:PRK08610 1 MPLVSMKEMLIDAKENGYAVGQYNLNNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTVVKMVEGLMHDLNITIPV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKE 160
Cdd:PRK08610 81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 161 CQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIAS 240
Cdd:PRK08610 161 CQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIAS 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 996413163 241 AKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRAK 286
Cdd:PRK08610 241 AKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRAK 286
|
|
| PRK07709 |
PRK07709 |
fructose-bisphosphate aldolase; Provisional |
1-285 |
1.01e-175 |
|
fructose-bisphosphate aldolase; Provisional
Pssm-ID: 169068 Cd Length: 285 Bit Score: 486.10 E-value: 1.01e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTIVKMVEGLMHDLNITIPV 80
Cdd:PRK07709 1 MPLVSMKEMLNKALEGKYAVGQFNMNNLEWTQAILAAAEEEKSPVILGVSEGAARHMTGFKTVVAMVKALIEEMNITVPV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKE 160
Cdd:PRK07709 81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGTVGGQEDDVIAEGVIYADPAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 161 CQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIAS 240
Cdd:PRK07709 161 CKHLVEATGIDCLAPALGSVHGPYKGEPNLGFAEMEQVRDFTGVPLVLHGGTGIPTADIEKAISLGTSKINVNTENQIEF 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 996413163 241 AKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:PRK07709 241 TKAVREVLNKDQEVYDPRKFIGPGRDAIKATVIGKIREFGSNGKA 285
|
|
| fruc_bis_ald_ |
TIGR01859 |
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; ... |
3-285 |
5.80e-161 |
|
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 130918 Cd Length: 282 Bit Score: 448.73 E-value: 5.80e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 3 LVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTIVKMVEGLMHDLNItIPVAI 82
Cdd:TIGR01859 1 LVNGKEILQKAKKEGYAVGAFNFNNLEWTQAILEAAEEENSPVIIQVSEGAIKYMGGYKMAVAMVKTLIERMSI-VPVAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 83 HLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKECQ 162
Cdd:TIGR01859 80 HLDHGSSYESCIKAIKAGFSSVMIDGSHLPFEENLALTKKVVEIAHAKGVSVEAELGTLGGIEDGVDEKEAELADPDEAE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 163 ELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAK 242
Cdd:TIGR01859 160 QFVKETGVDYLAAAIGTSHGKYKGEPGLDFERLKEIKELTNIPLVLHGASGIPEEQIKKAIKLGIAKINIDTDCRIAFTA 239
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 996413163 243 AVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:TIGR01859 240 AIRKVLTEKKDEYDPRKILGPAREAIKETVKEKMRLFGSAGKA 282
|
|
| Fba |
COG0191 |
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ... |
2-285 |
2.05e-153 |
|
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439961 Cd Length: 283 Bit Score: 429.51 E-value: 2.05e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 2 PLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMsGFYTIVKMVEGLMHdlNITIPVA 81
Cdd:COG0191 1 MLVSLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYA-GLEYLAAMVRAAAE--EASVPVA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 82 IHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVV--ADGIIYADPK 159
Cdd:COG0191 78 LHLDHGASFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEEDGVDvdDAEALYTDPE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 160 ECQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIA 239
Cdd:COG0191 158 EAAEFVEETGVDALAVAIGTVHGVYKGEPKLDFDRLKEIREAVPVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLA 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 996413163 240 SAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:COG0191 238 FTAAVREYLAENPDKYDPRKYLKPAREAMKEVVKEKIRLFGSAGKA 283
|
|
| cbbA |
TIGR00167 |
ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model ... |
1-285 |
9.72e-149 |
|
ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model include fructose-bisphosphate and tagatose-bisphosphate aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 272938 Cd Length: 288 Bit Score: 417.88 E-value: 9.72e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTIVKMVEGLMHDLNITIPV 80
Cdd:TIGR00167 1 MMLVDVKELLQDAKEEGYAIPAFNINNLETINAVLEAAAEEKSPVIIQFSNGAAKYIAGLGAISAMVKAMSEAYPYGVPV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDV--VADGIIYADP 158
Cdd:TIGR00167 81 ALHLDHGASEEDCAQAVKAGFSSVMIDGSHEPFEENIELTKKVVERAHKMGVSVEAELGTLGGEEDGVsvADESALYTDP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 159 KECQELVEKTGIDALAPALGSVHGPYKGEPK-LGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQ 237
Cdd:TIGR00167 161 EEAKEFVKLTGVDSLAAAIGNVHGVYKGEPKgLDFERLEEIQKYVNLPLVLHGGSGIPDEEIKKAISLGVVKVNIDTELQ 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 996413163 238 IASAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:TIGR00167 241 IAFAAAVRNYYAENKDYYDPRVWLRPGEKAMKEVVLEKIKLFGSANKA 288
|
|
| TBP_aldolase_IIB |
cd00947 |
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ... |
6-283 |
2.55e-144 |
|
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.
Pssm-ID: 238477 Cd Length: 276 Bit Score: 406.14 E-value: 2.55e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 6 MKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMsGFYTIVKMVEGLMHDLniTIPVAIHLD 85
Cdd:cd00947 1 TKELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYA-GLELLVAMVKAAAERA--SVPVALHLD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 86 HGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKECQELV 165
Cdd:cd00947 78 HGSSFELIKRAIRAGFSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVGDEGLLTDPEEAEEFV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 166 EKTGIDALAPALGSVHGPYKG-EPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAKAV 244
Cdd:cd00947 158 EETGVDALAVAIGTSHGAYKGgEPKLDFDRLKEIAERVNVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAAL 237
|
250 260 270
....*....|....*....|....*....|....*....
gi 996413163 245 RDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSN 283
Cdd:cd00947 238 REYLAENPKEFDPRKYLAPAIEAVKEVVKHKMELFGSAG 276
|
|
| F_bP_aldolase |
pfam01116 |
Fructose-bisphosphate aldolase class-II; |
4-284 |
1.04e-143 |
|
Fructose-bisphosphate aldolase class-II;
Pssm-ID: 460071 Cd Length: 276 Bit Score: 404.87 E-value: 1.04e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 4 VSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAAR-YMSGFYTIVKMVEGLMHDLNItiPVAI 82
Cdd:pfam01116 1 VNLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAkYAGGAEALAALVRAAAEAAGV--PVAL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 83 HLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKECQ 162
Cdd:pfam01116 79 HLDHGASFELIKEAIEAGFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIGGEEDGVVVDEKLYTDPEEAA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 163 ELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAK 242
Cdd:pfam01116 159 EFVEATGVDALAVAIGNVHGVYKPGPKLDFDRLKEIQEAVPVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTA 238
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 996413163 243 AVRDVLNNdkevYDPRKYLGPAREAIKETVKGKIKEFGTSNR 284
Cdd:pfam01116 239 AVREYPPN----KDPRKYLRPAEEAMKEVVKEKIRLFGSAGK 276
|
|
| PRK12857 |
PRK12857 |
class II fructose-1,6-bisphosphate aldolase; |
1-285 |
3.69e-118 |
|
class II fructose-1,6-bisphosphate aldolase;
Pssm-ID: 237235 Cd Length: 284 Bit Score: 340.55 E-value: 3.69e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYmSGFYTIVKMVEGLMHdlNITIPV 80
Cdd:PRK12857 1 MMLVTVAELLKKAEKGGYAVGAFNCNNMEIVQAIVAAAEAEKSPVIIQASQGAIKY-AGIEYISAMVRTAAE--KASVPV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVAD--GIIYADP 158
Cdd:PRK12857 78 ALHLDHGTDFEQVMKCIRNGFTSVMIDGSKLPLEENIALTKKVVEIAHAVGVSVEAELGKIGGTEDDITVDerEAAMTDP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 159 KECQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQI 238
Cdd:PRK12857 158 EEARRFVEETGVDALAIAIGTAHGPYKGEPKLDFDRLAKIKELVNIPIVLHGSSGVPDEAIRKAISLGVRKVNIDTNIRE 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 996413163 239 ASAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:PRK12857 238 AFVARLREVLEKNPDEIDPRKILGPAREAAKEVIREKIRLFGSAGKA 284
|
|
| gatY |
PRK12737 |
tagatose-bisphosphate aldolase subunit GatY; |
1-285 |
4.80e-111 |
|
tagatose-bisphosphate aldolase subunit GatY;
Pssm-ID: 183710 Cd Length: 284 Bit Score: 322.41 E-value: 4.80e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYmSGFYTIVKMVEGLMHDLNItiPV 80
Cdd:PRK12737 1 MYIISTKNMLKKAQAEGYAVPAFNIHNLETLQVVVETAAELRSPVILAGTPGTFSY-AGTDYIVAIAEVAARKYNI--PL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVAD--GIIYADP 158
Cdd:PRK12737 78 ALHLDHHEDLDDIKKKVRAGIRSVMIDGSHLSFEENIAIVKEVVEFCHRYDASVEAELGRLGGQEDDLVVDekDAMYTNP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 159 KECQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQI 238
Cdd:PRK12737 158 DAAAEFVERTGIDSLAVAIGTAHGLYKGEPKLDFERLAEIREKVSIPLVLHGASGVPDEDVKKAISLGICKVNVATELKI 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 996413163 239 ASAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:PRK12737 238 AFSDAVKKYFYENPKANDPRKYMTPGKAAMKEVVREKIKVCGSEGKL 284
|
|
| gatY |
PRK09195 |
tagatose-bisphosphate aldolase; Reviewed |
1-285 |
2.27e-109 |
|
tagatose-bisphosphate aldolase; Reviewed
Pssm-ID: 181690 Cd Length: 284 Bit Score: 318.22 E-value: 2.27e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMsGFYTIVKMVEGLMHDLNItiPV 80
Cdd:PRK09195 1 MYLVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAAELHSPVIIAGTPGTFSYA-GTEYLLAIVSAAAKQYHH--PL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADG--IIYADP 158
Cdd:PRK09195 78 ALHLDHHEKFDDIAQKVRSGVRSVMIDGSHLPFAQNISLVKEVVDFCHRFDVSVEAELGRLGGQEDDLQVDEadALYTDP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 159 KECQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQI 238
Cdd:PRK09195 158 AQAREFVEATGIDSLAVAIGTAHGMYKGEPKLDFDRLENIRQWVNIPLVLHGASGLPTKDIQQTIKLGICKVNVATELKI 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 996413163 239 ASAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:PRK09195 238 AFSQALKNYLTEHPEANDPRHYLQPAKSAMKDVVSKVIADCGCEGKA 284
|
|
| tag_bisphos_ald |
TIGR01858 |
class II aldolase, tagatose bisphosphate family; This model describes tagatose-1, ... |
3-285 |
2.21e-94 |
|
class II aldolase, tagatose bisphosphate family; This model describes tagatose-1,6-bisphosphate aldolases, and perhaps other closely related class II aldolases. This tetrameric, Zn2+-dependent enzyme is related to the class II fructose bisphosphate aldolase; fructose 1,6-bisphosphate and tagatose 1,6 bisphosphate differ only in chirality at C4.
Pssm-ID: 130917 Cd Length: 282 Bit Score: 279.82 E-value: 2.21e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 3 LVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYmSGFYTIVKMVEGLMHDLNItiPVAI 82
Cdd:TIGR01858 1 IVSTKYMLQDAQAGGYAVPAFNIHNLETIQAVVETAAEMRSPVILAGTPGTFKH-AGTEYIVALCSAASTTYNM--PLAL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 83 HLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVAD--GIIYADPKE 160
Cdd:TIGR01858 78 HLDHHESLDDIRQKVHAGVRSAMIDGSHFPFAQNVKLVKEVVDFCHRQDCSVEAELGRLGGVEDDLSVDeeDALYTDPQE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 161 CQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIAS 240
Cdd:TIGR01858 158 AKEFVEATGVDSLAVAIGTAHGLYKKTPKLDFDRLAEIREVVDVPLVLHGASDVPDEDVRRTIELGICKVNVATELKIAF 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 996413163 241 AKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:TIGR01858 238 SGAVKAYFAENPQANDPRYYMRPGKDAMKKVVRNKINVCGSAGRA 282
|
|
| PRK07315 |
PRK07315 |
fructose-bisphosphate aldolase; Provisional |
1-285 |
1.69e-92 |
|
fructose-bisphosphate aldolase; Provisional
Pssm-ID: 180926 Cd Length: 293 Bit Score: 275.61 E-value: 1.69e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTIVKMVEGLMHDLNITIPV 80
Cdd:PRK07315 1 MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGGYKVCKNLIENLVESMGITVPV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 81 AIHLDHGsSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIyADPKE 160
Cdd:PRK07315 81 AIHLDHG-HYEDALECIEVGYTSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGEL-APIED 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 161 CQELVEkTGIDALAPALGSVHGPYKGEPK-LGFKEMEEIGLST-GLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQI 238
Cdd:PRK07315 159 AKAMVE-TGIDFLAAGIGNIHGPYPENWEgLDLDHLEKLTEAVpGFPIVLHGGSGIPDDQIQEAIKLGVAKVNVNTECQI 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 996413163 239 ASAKAVRDVLNN---------DKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:PRK07315 238 AFANATRKFARDyeaneaeydKKKLFDPRKFLAPGVKAIQASVEERIDVFGSANKA 293
|
|
| PRK07084 |
PRK07084 |
class II fructose-1,6-bisphosphate aldolase; |
3-285 |
5.93e-92 |
|
class II fructose-1,6-bisphosphate aldolase;
Pssm-ID: 180829 Cd Length: 321 Bit Score: 275.07 E-value: 5.93e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 3 LVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSGfyTIVK-MVEG---LMHDLNITI 78
Cdd:PRK07084 9 LVNTREMFAKAVKGGYAIPAYNFNNMEQLQAIIQACVETKSPVILQVSKGARKYANA--TLLRyMAQGaveYAKELGCPI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 79 PVAIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADP 158
Cdd:PRK07084 87 PIVLHLDHGDSFELCKDCIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSAEHHTYTQP 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 159 KECQELVEKTGIDALAPALGSVHGPYK---GE--PKLGFKEMEEIGLST-GLPLVLHGGT-------------------- 212
Cdd:PRK07084 167 EEVEDFVKKTGVDSLAISIGTSHGAYKfkpGQcpPPLRFDILEEIEKRIpGFPIVLHGSSsvpqeyvktineyggklkda 246
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 996413163 213 -GIPTKDIQKAIPFGTAKINVNTENQIASAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKE-FGTSNRA 285
Cdd:PRK07084 247 iGIPEEQLRKAAKSAVCKINIDSDGRLAMTAAIRKVFDEKPEEFDPRKYLGPARDELKKLYKHKIINvLGSNGKA 321
|
|
| PRK05835 |
PRK05835 |
class II fructose-1,6-bisphosphate aldolase; |
3-284 |
2.26e-89 |
|
class II fructose-1,6-bisphosphate aldolase;
Pssm-ID: 180280 [Multi-domain] Cd Length: 307 Bit Score: 267.99 E-value: 2.26e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 3 LVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMsGFYTIVKMVEgLMHDLNITIPVAI 82
Cdd:PRK05835 2 LVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYM-GIDMAVGMVK-IMCERYPHIPVAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 83 HLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVAD--GIIYADPKE 160
Cdd:PRK05835 80 HLDHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMGIEDNISVDekDAVLVNPKE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 161 CQELVEKTGIDALAPALGSVHGP--YKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTK----------DIQ--KAIPF- 225
Cdd:PRK05835 160 AEQFVKESQVDYLAPAIGTSHGAfkFKGEPKLDFERLQEVKRLTNIPLVLHGASAIPDDvrksyldaggDLKgsKGVPFe 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 996413163 226 --------GTAKINVNTENQIASAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNR 284
Cdd:PRK05835 240 flqesvkgGINKVNTDTDLRIAFIAEVRKVANEDKSQFDLRKFFSPAQLALKNVVKERMKLLGSANK 306
|
|
| PRK08185 |
PRK08185 |
hypothetical protein; Provisional |
6-286 |
2.95e-86 |
|
hypothetical protein; Provisional
Pssm-ID: 181275 Cd Length: 283 Bit Score: 259.27 E-value: 2.95e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 6 MKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMS-GFYTIVKMVEglmhdLNITIPVAIHL 84
Cdd:PRK08185 1 MKELLKVAKEHQFAVGAFNVADSCFLRAVVEEAEANNAPAIIAIHPNELDFLGdNFFAYVRERA-----KRSPVPFVIHL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 85 DHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVV--ADGIIYADPKECQ 162
Cdd:PRK08185 76 DHGATIEDVMRAIRCGFTSVMIDGSLLPYEENVALTKEVVELAHKVGVSVEGELGTIGNTGTSIEggVSEIIYTDPEQAE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 163 ELVEKTGIDALAPALGSVHGPYK--GEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIAS 240
Cdd:PRK08185 156 DFVSRTGVDTLAVAIGTAHGIYPkdKKPELQMDLLKEINERVDIPLVLHGGSANPDAEIAESVQLGVGKINISSDMKYAF 235
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 996413163 241 AKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRAK 286
Cdd:PRK08185 236 FKKVREILSDNPSLYEPNQIYPSAIEAAKEVVRHKMDLFNSTGKAD 281
|
|
| PRK09196 |
PRK09196 |
fructose-bisphosphate aldolase class II; |
1-285 |
5.45e-82 |
|
fructose-bisphosphate aldolase class II;
Pssm-ID: 181691 Cd Length: 347 Bit Score: 250.64 E-value: 5.45e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYmSGFYTIVKMVEGLMhDLNITIPV 80
Cdd:PRK09196 1 MALISLRQLLDHAAEHGYGVPAFNVNNLEQVQAIMEAADETDSPVILQASAGARKY-AGEPFLRHLILAAV-EEYPHIPV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 81 AIHLDHGSSFEKCKEAIDAGFTSVMIDAS-------HSPFEENVATTKKVVEYAHEKGVSVEAELGTVG-------GQED 146
Cdd:PRK09196 79 VMHQDHGNSPATCQRAIQLGFTSVMMDGSlkadgktPASYEYNVDVTRKVVEMAHACGVSVEGELGCLGsletgmgGEED 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 147 DVVADGII-----YADPKECQELVEKTGIDALAPALGSVHGPYKGEPK-----LGFKEMEEIglSTGLP---LVLHGGT- 212
Cdd:PRK09196 159 GHGAEGKLshdqlLTDPEEAADFVKKTQVDALAIAIGTSHGAYKFTRKptgdvLAIDRIKEI--HARLPnthLVMHGSSs 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 213 --------------------GIPTKDIQKAIPFGTAKINVNTENQIASAKAVRDVLNNDKEVYDPRKYLGPAREAIKETV 272
Cdd:PRK09196 237 vpqelldiineyggdmpetyGVPVEEIQEGIKHGVRKVNIDTDLRLAMTGAIRRFLAENPSEFDPRKYLKPAMEAMKKIC 316
|
330
....*....|...
gi 996413163 273 KGKIKEFGTSNRA 285
Cdd:PRK09196 317 KARYEAFGTAGQA 329
|
|
| kbaY |
PRK12738 |
tagatose-bisphosphate aldolase subunit KbaY; |
1-284 |
6.04e-81 |
|
tagatose-bisphosphate aldolase subunit KbaY;
Pssm-ID: 183711 Cd Length: 286 Bit Score: 246.10 E-value: 6.04e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSgFYTIVKMVEGlmHDLNITIPV 80
Cdd:PRK12738 1 MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIA-LEEIYALCSA--YSTTYNMPL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDD--VVADGIIYADP 158
Cdd:PRK12738 78 ALHLDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDmsVDAESAFLTDP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 159 KECQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQI 238
Cdd:PRK12738 158 QEAKRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKI 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 996413163 239 ASAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNR 284
Cdd:PRK12738 238 AFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANR 283
|
|
| PRK06806 |
PRK06806 |
class II aldolase; |
1-285 |
1.98e-80 |
|
class II aldolase;
Pssm-ID: 180705 Cd Length: 281 Bit Score: 244.28 E-value: 1.98e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYmSGFYTI-VKMVEGLMhdlNITIP 79
Cdd:PRK06806 1 MPLVQMKELLKKANQENYGVGAFSVANMEMVMGAIKAAEELNSPIILQIAEVRLNH-SPLHLIgPLMVAAAK---QAKVP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 80 VAIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPK 159
Cdd:PRK06806 77 VAVHFDHGMTFEKIKEALEIGFTSVMFDGSHLPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGSEDIEMLLTSTT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 160 ECQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIA 239
Cdd:PRK06806 157 EAKRFAEETDVDALAVAIGNAHGMYNGDPNLRFDRLQEINDVVHIPLVLHGGSGISPEDFKKCIQHGIRKINVATATFNS 236
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 996413163 240 SAKAVRDvLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:PRK06806 237 VITAVNN-LVLNTPYSDYFTYHQDVIKAAYENVKKHMQIFGSENKA 281
|
|
| PRK06801 |
PRK06801 |
ketose 1,6-bisphosphate aldolase; |
1-285 |
8.98e-79 |
|
ketose 1,6-bisphosphate aldolase;
Pssm-ID: 180701 Cd Length: 286 Bit Score: 240.42 E-value: 8.98e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSgFYTIVKMV--EGLMHDlnitI 78
Cdd:PRK06801 1 MALISLANGLAHARKHGYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYIS-LESLVEAVkfEAARHD----I 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 79 PVAIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVV---ADGIIY 155
Cdd:PRK06801 76 PVVLNLDHGLHFEAVVRALRLGFSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGGDEGGALygeADSAKF 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 156 ADPKECQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTE 235
Cdd:PRK06801 156 TDPQLARDFVDRTGIDALAVAIGNAHGKYKGEPKLDFARLAAIHQQTGLPLVLHGGSGISDADFRRAIELGIHKINFYTG 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 996413163 236 NQIASAKAVRDVLNNDKEVYDP-RKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:PRK06801 236 MSQAALAAVEQRMTHRHAIYDEfAELLLGIEEAISDTVAQQMRIFGSAGQA 286
|
|
| gatY |
PRK07998 |
class II aldolase; |
1-285 |
1.39e-75 |
|
class II aldolase;
Pssm-ID: 181192 Cd Length: 283 Bit Score: 231.96 E-value: 1.39e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARyMSGFYTIVKMVEglMHDLNITIPV 80
Cdd:PRK07998 1 MPLVNGRILLDRIQEKHVLAGAFNTTNLETTISILNAIERSGLPNFIQIAPTNAQ-LSGYDYIYEIVK--RHADKMDVPV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKE 160
Cdd:PRK07998 78 SLHLDHGKTFEDVKQAVRAGFTSVMIDGAALPFEENIAFTKEAVDFAKSYGVPVEAELGAILGKEDDHVSEADCKTEPEK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 161 CQELVEKTGIDALAPALGSVHGPYKgEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIAS 240
Cdd:PRK07998 158 VKDFVERTGCDMLAVSIGNVHGLED-IPRIDIPLLKRIAEVSPVPLVIHGGSGIPPEILRSFVNYKVAKVNIASDLRKAF 236
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 996413163 241 AKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:PRK07998 237 ITTVGKAYVNNHNEANLARVMAKAKQAVEEDVYSKIKMMNSNHRL 281
|
|
| PRK13399 |
PRK13399 |
fructose-bisphosphate aldolase class II; |
1-285 |
1.71e-71 |
|
fructose-bisphosphate aldolase class II;
Pssm-ID: 184029 Cd Length: 347 Bit Score: 223.89 E-value: 1.71e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYtIVKMVEGLMhDLNITIPV 80
Cdd:PRK13399 1 MALITLRQLLDHAAENGYGVPAFNVNNMEQILAIMEAAEATDSPVILQASRGARKYAGDAM-LRHMVLAAA-EMYPDIPI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHSP-------FEENVATTKKVVEYAHEKGVSVEAELGTVG-------GQED 146
Cdd:PRK13399 79 CLHQDHGNSPATCQSAIRSGFTSVMMDGSLLAdgktpasYDYNVDVTRRVTEMAHAVGVSVEGELGCLGsletgeaGEED 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 147 DVVADG-----IIYADPKECQELVEKTGIDALAPALGSVHGPYKGEPK-----LGFKEMEEIglSTGLP---LVLHGGT- 212
Cdd:PRK13399 159 GVGAEGklshdQMLTDPDQAVDFVQRTGVDALAIAIGTSHGAYKFTRKpdgdiLAIDRIEEI--HARLPnthLVMHGSSs 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 213 --------------------GIPTKDIQKAIPFGTAKINVNTENQIASAKAVRDVLNNDKEVYDPRKYLGPAREAIKETV 272
Cdd:PRK13399 237 vpqelqeiinayggkmketyGVPVEEIQRGIKHGVRKVNIDTDIRLAMTGAIRKVLAEHPSEFDPRKALKPAMKAMTALC 316
|
330
....*....|...
gi 996413163 273 KGKIKEFGTSNRA 285
Cdd:PRK13399 317 KQRFEAFGTAGQA 329
|
|
| PLN02858 |
PLN02858 |
fructose-bisphosphate aldolase |
5-285 |
2.38e-57 |
|
fructose-bisphosphate aldolase
Pssm-ID: 215463 [Multi-domain] Cd Length: 1378 Bit Score: 198.15 E-value: 2.38e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 5 SMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARyMSGFYTIVKMVEGLMHDlniTIPVAIHL 84
Cdd:PLN02858 1101 STKELLLNAEKGGYAVGAFNVYNLEGIEAVVAAAEAEKSPAILQVHPGALK-QGGIPLVSCCIAAAEQA---SVPITVHF 1176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 85 DHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGI--IYADPKECQ 162
Cdd:PLN02858 1177 DHGTSKHELLEALELGFDSVMVDGSHLSFTENISYTKSISSLAHSKGLMVEAELGRLSGTEDGLTVEEYeaKLTDVDQAK 1256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 163 ELVEKTGIDALAPALGSVHGPY-KGEPKLGF---KEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQI 238
Cdd:PLN02858 1257 EFIDETGIDALAVCIGNVHGKYpASGPNLRLdllKELRALSSKKGVLLVLHGASGLPESLIKECIENGVRKFNVNTEVRT 1336
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 996413163 239 ASAKAVrdvlnNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRA 285
Cdd:PLN02858 1337 AYMEAL-----SSPKKTDLIDVMSAAKEAMKAVVAEKLRLFGSAGKA 1378
|
|
| FTBP_aldolase_II |
cd00453 |
Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1, ... |
7-283 |
8.26e-57 |
|
Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to yield fructose-1,6-bisphosphate. TBP-aldolase is tetrameric and produces tagarose-1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. Although structurally similar, the class I aldolases use a different mechanism and are believed to have an independent evolutionary origin.
Pssm-ID: 238255 Cd Length: 340 Bit Score: 185.78 E-value: 8.26e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 7 KEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSGF---------YTIVKMVEG--LMHDLN 75
Cdd:cd00453 2 QKVFQVAKENNFALPAVNCVGTDSINAVLETAAKVKAPVIVQFSNGGASFIAGKgvksdvpqgAAILGAISGahHVHQMA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 76 IT--IPVAIHLDH--GSSFEKCKEAIDAG-----------FTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGT 140
Cdd:cd00453 82 EHygVPVILHTDHcaKKLLPWIDGLLDAGekhfaatgkplFSSHMIDLSEESLQENIEICSKYLERMSKIGMTLEIELGC 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 141 VGGQEDDVVADGI----IYADPKECQELVEKTG----IDALAPALGSVHGPYK-GEPKLGFKEMEEI---------GLST 202
Cdd:cd00453 162 TGGEEDGVDNSHMdasaLYTQPEDVDYAYTELSkispRFTIAASFGNVHGVYKkGNVVLTPTILRDSqeyvskkhnLPHN 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 203 GLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAKAV------------------RDVLNNDKEVYDPRKYLGPA 264
Cdd:cd00453 242 SLNFVFHGGSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGVlnyykaneaylqgqlgnpKGEDQPNKKYYDPRVWLRAG 321
|
330
....*....|....*....
gi 996413163 265 REAIKETVKGKIKEFGTSN 283
Cdd:cd00453 322 QTSMIARLEKAFQELNAID 340
|
|
| FBP_aldolase_IIA |
cd00946 |
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the ... |
8-284 |
3.05e-37 |
|
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is homodimeric and used in gluconeogenesis and glycolysis. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.
Pssm-ID: 238476 Cd Length: 345 Bit Score: 134.80 E-value: 3.05e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 8 EMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSG--------FYTIVKMVEGLMHDLNIT-- 77
Cdd:cd00946 6 KLFDYAKENGFAIPAVNCTSSSTINAVLEAARDAKSPIIIQFSNGGAAFYAGkglknekqKASIAGAIAAAHHVRSMAeh 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 78 --IPVAIHLDHGSS---------FEKCKEAIDAG----FTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVG 142
Cdd:cd00946 86 ygVPVVLHTDHCAKkllpwfdglLEADEEYFKQHgeplFSSHMLDLSEEPLEENIEICKKYLERMAKINMWLEMEIGITG 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 143 GQEDDVVADGI----IYADPKEC----QELVEKTGIDALAPALGSVHGPYKG-----EPKLGFKEM----EEIGLSTGLP 205
Cdd:cd00946 166 GEEDGVDNSGVdnaeLYTQPEDVwyvyEALSKISPNFSIAAAFGNVHGVYKPgnvklQPEILGEHQdyvrEKLGLADDKP 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 206 L--VLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAKAVRD-VLNN-----------------DKEVYDPRKYLGPAR 265
Cdd:cd00946 246 LyfVFHGGSGSTKEEIREAISYGVVKMNIDTDTQWAYWEGVRNyYLKNedylqgqignpegpdkpNKKYYDPRVWLREGE 325
|
330
....*....|....*....
gi 996413163 266 EAIKETVKGKIKEFGTSNR 284
Cdd:cd00946 326 KSMVARVKKAFEDLNSVNK 344
|
|
| PRK09197 |
PRK09197 |
fructose-bisphosphate aldolase; Provisional |
1-273 |
4.13e-34 |
|
fructose-bisphosphate aldolase; Provisional
Pssm-ID: 236406 Cd Length: 350 Bit Score: 126.45 E-value: 4.13e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 1 MPLVS---MKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSGfYTIVKMVEGLM------ 71
Cdd:PRK09197 1 PGVATgedYQEMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAG-KGVKDDGQGAAvlgaia 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 72 -----HDL--NITIPVAIHLDHgssfekC-KEA-------IDAG-----------FTSVMIDASHSPFEENVATTKKVVE 125
Cdd:PRK09197 80 gakhvHEVaeHYGVPVILHTDH------CaKKLlpwidglLDAGekhfaaggkplFSSHMIDLSEEPLEENIEICSKYLE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 126 YAHEKGVSVEAELGTVGGQEDDVVADGII----YADPKECQELVEKTGIDA----LAPALGSVHGPYK-G----EPKLGF 192
Cdd:PRK09197 154 RMAKAGMTLEIELGVTGGEEDGVDNSHEDnsklYTQPEDVLYAYEALGKISgrftIAASFGNVHGVYKpGnvklRPEILK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996413163 193 KEMEEIGLSTGLP-----LVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAKAVRD------------VLNND---- 251
Cdd:PRK09197 234 DSQEYVSKKFGLPakpfdFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDyyfknydylqgqVGNPEgedk 313
|
330 340
....*....|....*....|....
gi 996413163 252 --KEVYDPRKYLGPAREAIKETVK 273
Cdd:PRK09197 314 pnKKYYDPRVWLRAAEASMAARLE 337
|
|
| |
