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Conserved domains on  [gi|996870425|emb|CXP94339|]
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putative glycine betaine/carnitine/choline transport system permease protein [Staphylococcus aureus]

Protein Classification

ABC transporter permease( domain architecture ID 10003065)

ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of substrates including gylcine betaine, choline, and carnitine

Gene Ontology:  GO:0140359|GO:0042626|GO:0055085|GO:0016020
PubMed:  25750732|24638992|31571164|27273632|26517919|18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 5-181 3.46e-64

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 198.35  E-value: 3.46e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425   5 LLQQLFNYYVTNFGYLWDLFFKHLLMSVYGVLFAALIGIPLGILLARYTKLSGFVITIANIIQTVPVIAMLAILMLVMGL 84
Cdd:COG1174    1 MNLSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  85 GSETVVLTVFLYALLPIIKNTYTGIASVDANIKDAGKGMGMTRNQVLRMIELPLSVSVIIGGIRIALVVAIGVVAVGSFI 164
Cdd:COG1174   81 GPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALI 160

                        170
                 ....*....|....*..
gi 996870425 165 GAPTLGDIVIRGTNATD 181
Cdd:COG1174  161 GAGGLGDLIFDGLQLNN 177
 
Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 5-181 3.46e-64

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 198.35  E-value: 3.46e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425   5 LLQQLFNYYVTNFGYLWDLFFKHLLMSVYGVLFAALIGIPLGILLARYTKLSGFVITIANIIQTVPVIAMLAILMLVMGL 84
Cdd:COG1174    1 MNLSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  85 GSETVVLTVFLYALLPIIKNTYTGIASVDANIKDAGKGMGMTRNQVLRMIELPLSVSVIIGGIRIALVVAIGVVAVGSFI 164
Cdd:COG1174   81 GPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALI 160

                        170
                 ....*....|....*..
gi 996870425 165 GAPTLGDIVIRGTNATD 181
Cdd:COG1174  161 GAGGLGDLIFDGLQLNN 177
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
35-176 1.79e-14

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 71.28  E-value: 1.79e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  35 VLFAALIGIPLGILLARYTKLSGFVITIANIIQTVPVIAMLAILMLVMGLGSETVVLTVFLYALLPIIKNTYTGIASVDA 114
Cdd:PRK10952 157 LLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTILGINQVPA 236

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 996870425 115 NIKDAGKGMGMTRNQVLRMIELPLSVSVIIGGIRIALVVAIGVVAVGSFIGAPTLGDIVIRG 176
Cdd:PRK10952 237 DLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRG 298
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 27-175 1.20e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 58.83  E-value: 1.20e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  27 HLLMSVYGVLFAALIGIPLGILLARYT-KLSGFVITIANIIQTVPVIAMLAILMLVMGL---------GSETVVLTVFLY 96
Cdd:cd06261    4 TLLLALIATLLALVLGLLLGIILARKRgKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVllgwgilpgLGLPALILALLL 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 996870425  97 ALLPIIKNTYTGIASVDANIKDAGKGMGMTRNQVLRMIELPLSVSVIIGGIRIALVVAIGVVAVGSFIGAPTLGDIVIR 175
Cdd:cd06261   84 IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGTG 162
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 42-211 2.48e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 57.69  E-value: 2.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425   42 GIPLGILLARY--TKLSGFVITIANIIQTVPVIAMLAIL-----MLVMGLGSETVVLTVFLYALLPIIKNTYTGIASVDA 114
Cdd:pfam00528   1 GIPLGIIAALRrgRRLDRLLRPLIDLLQALPSFVLAILLvviaiLSILGHGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  115 NIKDAGKGMGMTRNQVLRMIELPLSVSVIIGGIRIALVVAIGVVAVGSFIGA-PTLGDIVIRGTNATD---GTTFILAGA 190
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSwPGLGLLLIEAILGYDypeIQGPVLAAA 160

                         170       180
                  ....*....|....*....|.
gi 996870425  191 IPIAIIAIVIDVLLRFLEKRL 211
Cdd:pfam00528 161 LILLLLNLLVDILQRLLDPRV 181
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 3-132 3.63e-07

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 49.46  E-value: 3.63e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425    3 GNLLQQLFNYYVTNFGYLWDLFFKHLLMSVYGVLFAALIGIPLGILLARYT----KLSGFVITIANIIQTVPVIAMLAIL 78
Cdd:TIGR01097  39 ADLLGRMFPPDWSYLPRILKALLETLAMAILGTVLAAVLAVPLALLAARNItpspWLYGLARLLLNFLRAIPELVWALIF 118

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 996870425   79 MLVMGLGSETVVLTVFLYALLPIIKNTYTGIASVDANIKDAGKGMGMTRNQVLR 132
Cdd:TIGR01097 119 VAAVGLGPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIR 172
ABC_perm1 NF038017
ABC transporter permease; Proteins of this family are the permease subunit of an ABC ...
 28-134 9.88e-03

ABC transporter permease; Proteins of this family are the permease subunit of an ABC transporter complex, which may be involved in tungstate uptake.


Pssm-ID: 411610 [Multi-domain]  Cd Length: 184  Bit Score: 35.98  E-value: 9.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  28 LLMSVYGVLFAALIGIPLGILLA-RYTKLSGFVITIANIIQTVP-VIAMLAILML--------VMGL--GSETVVLTVFL 95
Cdd:NF038017   2 LRVSGTATLIAALIGIPLGALLAlRRFPGRRLVISLLNTLMGLPpVVVGLIVYLLlsrsgplgFLGLlyTPTAMIIAQAV 81

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 996870425  96 YALLPIIKNTYTGIASVDANIKDAGKGMGMTRNQVLRMI 134
Cdd:NF038017  82 LALPIVAGLTLAAVQGLDPELRLQILSLGATRWQALWTL 120
 
Name Accession Description Interval E-value
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 5-181 3.46e-64

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 198.35  E-value: 3.46e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425   5 LLQQLFNYYVTNFGYLWDLFFKHLLMSVYGVLFAALIGIPLGILLARYTKLSGFVITIANIIQTVPVIAMLAILMLVMGL 84
Cdd:COG1174    1 MNLSLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  85 GSETVVLTVFLYALLPIIKNTYTGIASVDANIKDAGKGMGMTRNQVLRMIELPLSVSVIIGGIRIALVVAIGVVAVGSFI 164
Cdd:COG1174   81 GPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALI 160

                        170
                 ....*....|....*..
gi 996870425 165 GAPTLGDIVIRGTNATD 181
Cdd:COG1174  161 GAGGLGDLIFDGLQLNN 177
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 21-151 1.17e-24

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 97.91  E-value: 1.17e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  21 WDLFFKHLLMSVY----GVLFAALIGIPLGILLARYTKLSGFVITIANIIQTVPVIAMLAILMLVMGLGSETVVLTVFLY 96
Cdd:COG0600   56 SGELWEHLLASLLrvllGFALAALLGVPLGLLLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLG 135

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 996870425  97 ALLPIIKNTYTGIASVDANIKDAGKGMGMTRNQVLRMIELPLSVSVIIGGIRIAL 151
Cdd:COG0600  136 AFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIAL 190
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
35-176 1.79e-14

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 71.28  E-value: 1.79e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  35 VLFAALIGIPLGILLARYTKLSGFVITIANIIQTVPVIAMLAILMLVMGLGSETVVLTVFLYALLPIIKNTYTGIASVDA 114
Cdd:PRK10952 157 LLFCIVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTILGINQVPA 236

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 996870425 115 NIKDAGKGMGMTRNQVLRMIELPLSVSVIIGGIRIALVVAIGVVAVGSFIGAPTLGDIVIRG 176
Cdd:PRK10952 237 DLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRG 298
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 27-175 1.20e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 58.83  E-value: 1.20e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  27 HLLMSVYGVLFAALIGIPLGILLARYT-KLSGFVITIANIIQTVPVIAMLAILMLVMGL---------GSETVVLTVFLY 96
Cdd:cd06261    4 TLLLALIATLLALVLGLLLGIILARKRgKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVllgwgilpgLGLPALILALLL 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 996870425  97 ALLPIIKNTYTGIASVDANIKDAGKGMGMTRNQVLRMIELPLSVSVIIGGIRIALVVAIGVVAVGSFIGAPTLGDIVIR 175
Cdd:cd06261   84 IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGTG 162
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 42-211 2.48e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 57.69  E-value: 2.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425   42 GIPLGILLARY--TKLSGFVITIANIIQTVPVIAMLAIL-----MLVMGLGSETVVLTVFLYALLPIIKNTYTGIASVDA 114
Cdd:pfam00528   1 GIPLGIIAALRrgRRLDRLLRPLIDLLQALPSFVLAILLvviaiLSILGHGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  115 NIKDAGKGMGMTRNQVLRMIELPLSVSVIIGGIRIALVVAIGVVAVGSFIGA-PTLGDIVIRGTNATD---GTTFILAGA 190
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSwPGLGLLLIEAILGYDypeIQGPVLAAA 160

                         170       180
                  ....*....|....*....|.
gi 996870425  191 IPIAIIAIVIDVLLRFLEKRL 211
Cdd:pfam00528 161 LILLLLNLLVDILQRLLDPRV 181
PRK10160 PRK10160
taurine ABC transporter permease TauC;
20-151 1.21e-09

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 56.72  E-value: 1.21e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  20 LWDLFFKHLLMSVYGVLFAALIGIPLGILLARYTKLSGFVITIANIIQTVPVIAMLAILMLVMGLGSETVVLTVFLYALL 99
Cdd:PRK10160  76 LWQHLAASLTRIVLALLAAVVIGIPVGIAMGLSPTVRGILDPLIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFA 155

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 996870425 100 PIIKNTYTGIASVDANIKDAGKGMGMTRNQVLRMIELPLSVSVIIGGIRIAL 151
Cdd:PRK10160 156 PVAMSALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGL 207
ssuC PRK11365
aliphatic sulfonate ABC transporter permease SsuC;
18-151 1.91e-07

aliphatic sulfonate ABC transporter permease SsuC;


Pssm-ID: 183100  Cd Length: 263  Bit Score: 50.32  E-value: 1.91e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  18 GYLWdlffKHLLMSVYGVLFAALIGIPLGILLARYTKLSGF----VITIANIIQTVPVIAMLAILMLVMGLGSETVVLTV 93
Cdd:PRK11365  56 GELW----QHLAISSWRALIGFSIGGSLGLILGLISGLSRWgerlLDTSIQMLRNVPHLALIPLVILWFGIDESAKIFLV 131

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 996870425  94 FLYALLPIIKNTYTGIASVDANIKDAGKGMGMTRNQVLRMIELPLSVSVIIGGIRIAL 151
Cdd:PRK11365 132 ALGTLFPIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPSIMVGVRFAL 189
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 10-144 3.45e-07

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 49.30  E-value: 3.45e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  10 FNYYVTNFGYLWDLFFKHLLMSVYGVLFAALIGIPLGIL-LARYTKLSGFVITIANIIQTVPVIAMLaiLMLVMGLGSET 88
Cdd:COG0765    5 FSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALArLSPNPVLRWLATAYVEFFRGTPLLVQL--FFIYFGLPLLG 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 996870425  89 VVLTVFLYALLPIIKNT--YT------GIASVDANIKDAGKGMGMTRNQVLRMIELPLSVSVII 144
Cdd:COG0765   83 IDLSPFVAAVIALTLNSaaYLaeivraGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIIL 146
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 3-132 3.63e-07

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 49.46  E-value: 3.63e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425    3 GNLLQQLFNYYVTNFGYLWDLFFKHLLMSVYGVLFAALIGIPLGILLARYT----KLSGFVITIANIIQTVPVIAMLAIL 78
Cdd:TIGR01097  39 ADLLGRMFPPDWSYLPRILKALLETLAMAILGTVLAAVLAVPLALLAARNItpspWLYGLARLLLNFLRAIPELVWALIF 118

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 996870425   79 MLVMGLGSETVVLTVFLYALLPIIKNTYTGIASVDANIKDAGKGMGMTRNQVLR 132
Cdd:TIGR01097 119 VAAVGLGPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIR 172
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 3-145 7.41e-07

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 48.54  E-value: 7.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425   3 GNLLQQLFNYYVTNFGYLWDLFFKHLLMSVYGVLFAALIGIPLGILLARYTKLSGFVITIA----NIIQTVPVIAMLAIL 78
Cdd:COG3639   32 ADFLSRFFPPDWSYLPDLLSALLETLAIALLGTLLGAVLALPLAFLAARNLAPNPWVRLLArrllNVLRAIPELVWALIF 111

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 996870425  79 MLVMGLGSETVVLTVFLYALLPIIKNTYTGIASVDANIKDAGKGMGMTRNQVLRMIELPLSVSVIIG 145
Cdd:COG3639  112 VAAVGLGPFAGVLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRLQVIRYGVLPQVLPQFLS 178
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
18-146 3.06e-05

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 44.38  E-value: 3.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  18 GYLWDLFFKHLLMSVYGVLFAALIGIPLGILLARY-TKLSGFVITIANIIQTVP--VIAmLAILMLVMGLG----SETVV 90
Cdd:COG1178  334 PSLLRALLNSLLLALLAALLAVLLALLLAYLVRRRrGRLARLLDRLAMLPYAVPgiVLG-LGLLLLFNRPLplllYGTLA 412

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 996870425  91 LTVFLYAL--LPI-IKNTYTGIASVDANIKDAGKGMGMTRNQVLRMIELPLSVSVIIGG 146
Cdd:COG1178  413 ILVLAYVVrfLPFaLRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAA 471
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 28-102 6.94e-04

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 40.05  E-value: 6.94e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  28 LLMSVYGVLFAALIGIPLGILLA--RYTKLSGFVITIANIIQTVP--VIAMLAILMLVMGLG---------SETVVLTVF 94
Cdd:COG0601   99 LELALLALLLALLIGIPLGILAAlrRGSWLDRLITVLALLGISIPsfWLGLLLILLFAVKLGwlpvsgrvsPWEDFLDAL 178


                 ....*...
gi 996870425  95 LYALLPII 102
Cdd:COG0601  179 RHLILPAL 186
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
19-146 1.15e-03

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 39.37  E-value: 1.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  19 YLWDLFFKHLLMSVYGVLFAALIGIPLGILLARYT-KLSGFVITIANIIQTVPVIAM-LAILML---------------- 80
Cdd:COG1178   51 YLWRALGNTLLLALLVTLLSLLLGVPLAWLLARTDfPGRRLLRWLLLLPLALPPYVVaLAWIALfgpngllntllralfg 130

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 996870425  81 -----VMGLGSETVVLTVFLYALlpIIKNTYTGIASVDANIKDAGKGMGMTRNQVLRMIELPLSVSVIIGG 146
Cdd:COG1178  131 leppdIYGLGGIILVLVLFNYPY--VYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAG 199
ABC_perm1 NF038017
ABC transporter permease; Proteins of this family are the permease subunit of an ABC ...
 28-134 9.88e-03

ABC transporter permease; Proteins of this family are the permease subunit of an ABC transporter complex, which may be involved in tungstate uptake.


Pssm-ID: 411610 [Multi-domain]  Cd Length: 184  Bit Score: 35.98  E-value: 9.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 996870425  28 LLMSVYGVLFAALIGIPLGILLA-RYTKLSGFVITIANIIQTVP-VIAMLAILML--------VMGL--GSETVVLTVFL 95
Cdd:NF038017   2 LRVSGTATLIAALIGIPLGALLAlRRFPGRRLVISLLNTLMGLPpVVVGLIVYLLlsrsgplgFLGLlyTPTAMIIAQAV 81

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 996870425  96 YALLPIIKNTYTGIASVDANIKDAGKGMGMTRNQVLRMI 134
Cdd:NF038017  82 LALPIVAGLTLAAVQGLDPELRLQILSLGATRWQALWTL 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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