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Conserved domains on  [gi|999734282|emb|CZM19663|]
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dephospho-CoA kinase/protein folding accessory domain-containing protein [Legionella pneumophila]

Protein Classification

bifunctional GrpB family protein/GNAT family N-acetyltransferase( domain architecture ID 11148454)

bifunctional GrpB family protein/GNAT family N-acetyltransferase which contains an N-terminal domain similar to glutamate-rich protein GrpB and may be a nucleotidyltransferase, and a C-terminal domain which may catalyze the transfer of an acetyl group from acetyl-CoA to a substrate

EC:  2.3.1.-
PubMed:  10940244

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GrpB COG2320
GrpB domain, predicted nucleotidyltransferase, UPF0157 family [General function prediction ...
 10-172 4.47e-86

GrpB domain, predicted nucleotidyltransferase, UPF0157 family [General function prediction only];


:

Pssm-ID: 441894  Cd Length: 166  Bit Score: 255.58  E-value: 4.47e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282  10 IEVVSYDANWPMQFEQEAERIKKALGSNCIEIHHIGSTSVPGLAAKPIIDMIPVVLELSKVDSANAAMKALGYEAKGEYG 89
Cdd:COG2320    2 IELVPYDPEWPEQFEREAARIRAALGDRALRIEHIGSTAVPGLAAKPIIDILVVVADLEDLDALVEALEALGYERLGEDG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282  90 IPFRRYFQKGDNQRTHHAHIFEFGNPEIERHLKFRDWMRANPEDRVAYARLKQELAHQHPYDITAYCVGKEDFIAAIDRK 169
Cdd:COG2320   82 IPGRRFFRKGDGGRTHHLHVREAGSPEWRRHLLFRDYLRAHPEAAAEYAALKRELAARYPDDRDAYTEAKTPFIEEILAR 161


                 ...
gi 999734282 170 AGF 172
Cdd:COG2320  162 ALA 164
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 209-318 1.31e-10

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


:

Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 58.46  E-value: 1.31e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282 209 WTFEHEAHVHFVLSQGSDIIGYAHLQLWPHKRAALRIIVIDEEKRNHQYGGQFLALCEKWLKTQGYQSLHVESSPDALRF 288
Cdd:COG1246   21 YALEEEIGEFWVAEEDGEIVGCAALHPLDEDLAELRSLAVHPDYRGRGIGRRLLEALLAEARELGLKRLFLLTTSAAIHF 100

                         90       100       110
                 ....*....|....*....|....*....|.
gi 999734282 289 YRNNDYIDMPFDD-PDGYEGDARDTAVGKIL 318
Cdd:COG1246  101 YEKLGFEEIDKEDlPYAKVWQRDSVVMEKDL 131
 
Name Accession Description Interval E-value
GrpB COG2320
GrpB domain, predicted nucleotidyltransferase, UPF0157 family [General function prediction ...
 10-172 4.47e-86

GrpB domain, predicted nucleotidyltransferase, UPF0157 family [General function prediction only];


Pssm-ID: 441894  Cd Length: 166  Bit Score: 255.58  E-value: 4.47e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282  10 IEVVSYDANWPMQFEQEAERIKKALGSNCIEIHHIGSTSVPGLAAKPIIDMIPVVLELSKVDSANAAMKALGYEAKGEYG 89
Cdd:COG2320    2 IELVPYDPEWPEQFEREAARIRAALGDRALRIEHIGSTAVPGLAAKPIIDILVVVADLEDLDALVEALEALGYERLGEDG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282  90 IPFRRYFQKGDNQRTHHAHIFEFGNPEIERHLKFRDWMRANPEDRVAYARLKQELAHQHPYDITAYCVGKEDFIAAIDRK 169
Cdd:COG2320   82 IPGRRFFRKGDGGRTHHLHVREAGSPEWRRHLLFRDYLRAHPEAAAEYAALKRELAARYPDDRDAYTEAKTPFIEEILAR 161


                 ...
gi 999734282 170 AGF 172
Cdd:COG2320  162 ALA 164
GrpB pfam04229
GrpB protein; This family has been suggested to belong to the nucleotidyltransferase ...
 10-169 9.43e-77

GrpB protein; This family has been suggested to belong to the nucleotidyltransferase superfamily. It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme.


Pssm-ID: 461232  Cd Length: 161  Bit Score: 231.65  E-value: 9.43e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282   10 IEVVSYDANWPMQFEQEAERIKKALGSNCIEIHHIGSTSVPGLAAKPIIDMIPVVLELSKVDSANAAMKALGYEaKGEYG 89
Cdd:pfam04229   2 VELVPYDPEWPAQFEREKARLRAALGDNALRIEHIGSTSVPGLAAKPIIDILVEVEDLADEDSLVPALEAAGYL-RGEPG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282   90 IPFRRYFQKG-DNQRTHHAHIFEFGNPEIERHLKFRDWMRANPEDRVAYARLKQELAHQHPYDITAYCVGKEDFIAAIDR 168
Cdd:pfam04229  81 IPGRRFFRKGyDPGRTHHLHVREAGSPEWRRHLLFRDYLRAHPEAAAEYAALKRELAAQYPDDRDAYTDAKTPFIREILK 160


                  .
gi 999734282  169 K 169
Cdd:pfam04229 161 R 161
coaE PRK03333
dephospho-CoA kinase/protein folding accessory domain-containing protein; Provisional
 11-170 4.58e-25

dephospho-CoA kinase/protein folding accessory domain-containing protein; Provisional


Pssm-ID: 179560 [Multi-domain]  Cd Length: 395  Bit Score: 103.93  E-value: 4.58e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282  11 EVVSYDANWPMQFEQEAERIKKALGSNCIEIHHIGSTSVPGLAAKPIIDMIPVVLELSKVDSANAAMKALGY-------- 82
Cdd:PRK03333 213 RLVPADPSWPAQAQRIVARLKTAAGHKALRVDHIGSTAVPGLDAKDVIDIQVTVESLAVADELAEPLAAAGFprlpgitq 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282  83 -EAKGEYGIPFR---RYFQKGDNQRTHHAHIFEFGNPEIERHLKFRDWMRANPEDRVAYARLKQELAHQHPYDITAYCVG 158
Cdd:PRK03333 293 dTPKPDDPDPALwgkRLHASADPGRPVNLHVRVDGWPGQRFALLFRDWLRADPAARAEYLAVKRRAARRADGDTAAYADA 372

                        170
                 ....*....|..
gi 999734282 159 KEDFIAAIDRKA 170
Cdd:PRK03333 373 KEPWFLDAYPRA 384
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 209-318 1.31e-10

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 58.46  E-value: 1.31e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282 209 WTFEHEAHVHFVLSQGSDIIGYAHLQLWPHKRAALRIIVIDEEKRNHQYGGQFLALCEKWLKTQGYQSLHVESSPDALRF 288
Cdd:COG1246   21 YALEEEIGEFWVAEEDGEIVGCAALHPLDEDLAELRSLAVHPDYRGRGIGRRLLEALLAEARELGLKRLFLLTTSAAIHF 100

                         90       100       110
                 ....*....|....*....|....*....|.
gi 999734282 289 YRNNDYIDMPFDD-PDGYEGDARDTAVGKIL 318
Cdd:COG1246  101 YEKLGFEEIDKEDlPYAKVWQRDSVVMEKDL 131
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 214-294 1.27e-07

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 48.60  E-value: 1.27e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282  214 EAHVHFVLSQGSDIIGYAHLQLWPHKRAALRI-IVIDEEKRNHQYGGQFLALCEKWLKTQGYQSLHVESSPDALRFYRNN 292
Cdd:pfam13508   1 PGGRFFVAEDDGKIVGFAALLPLDDEGALAELrLAVHPEYRGQGIGRALLEAAEAAAKEGGIKLLELETTNRAAAFYEKL 80


                  ..
gi 999734282  293 DY 294
Cdd:pfam13508  81 GF 82
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 218-280 6.67e-05

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 40.34  E-value: 6.67e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 999734282 218 HFVLSQGSDIIGYAHLQLWPHKRAALRI--IVIDEEKRNHQYGGQFLALCEKWLKTQGYQSLHVE 280
Cdd:cd04301    1 FLVAEDDGEIVGFASLSPDGSGGDTAYIgdLAVLPEYRGKGIGSALLEAAEEEARERGAKRLRLE 65
 
Name Accession Description Interval E-value
GrpB COG2320
GrpB domain, predicted nucleotidyltransferase, UPF0157 family [General function prediction ...
 10-172 4.47e-86

GrpB domain, predicted nucleotidyltransferase, UPF0157 family [General function prediction only];


Pssm-ID: 441894  Cd Length: 166  Bit Score: 255.58  E-value: 4.47e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282  10 IEVVSYDANWPMQFEQEAERIKKALGSNCIEIHHIGSTSVPGLAAKPIIDMIPVVLELSKVDSANAAMKALGYEAKGEYG 89
Cdd:COG2320    2 IELVPYDPEWPEQFEREAARIRAALGDRALRIEHIGSTAVPGLAAKPIIDILVVVADLEDLDALVEALEALGYERLGEDG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282  90 IPFRRYFQKGDNQRTHHAHIFEFGNPEIERHLKFRDWMRANPEDRVAYARLKQELAHQHPYDITAYCVGKEDFIAAIDRK 169
Cdd:COG2320   82 IPGRRFFRKGDGGRTHHLHVREAGSPEWRRHLLFRDYLRAHPEAAAEYAALKRELAARYPDDRDAYTEAKTPFIEEILAR 161


                 ...
gi 999734282 170 AGF 172
Cdd:COG2320  162 ALA 164
GrpB pfam04229
GrpB protein; This family has been suggested to belong to the nucleotidyltransferase ...
 10-169 9.43e-77

GrpB protein; This family has been suggested to belong to the nucleotidyltransferase superfamily. It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme.


Pssm-ID: 461232  Cd Length: 161  Bit Score: 231.65  E-value: 9.43e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282   10 IEVVSYDANWPMQFEQEAERIKKALGSNCIEIHHIGSTSVPGLAAKPIIDMIPVVLELSKVDSANAAMKALGYEaKGEYG 89
Cdd:pfam04229   2 VELVPYDPEWPAQFEREKARLRAALGDNALRIEHIGSTSVPGLAAKPIIDILVEVEDLADEDSLVPALEAAGYL-RGEPG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282   90 IPFRRYFQKG-DNQRTHHAHIFEFGNPEIERHLKFRDWMRANPEDRVAYARLKQELAHQHPYDITAYCVGKEDFIAAIDR 168
Cdd:pfam04229  81 IPGRRFFRKGyDPGRTHHLHVREAGSPEWRRHLLFRDYLRAHPEAAAEYAALKRELAAQYPDDRDAYTDAKTPFIREILK 160


                  .
gi 999734282  169 K 169
Cdd:pfam04229 161 R 161
coaE PRK03333
dephospho-CoA kinase/protein folding accessory domain-containing protein; Provisional
 11-170 4.58e-25

dephospho-CoA kinase/protein folding accessory domain-containing protein; Provisional


Pssm-ID: 179560 [Multi-domain]  Cd Length: 395  Bit Score: 103.93  E-value: 4.58e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282  11 EVVSYDANWPMQFEQEAERIKKALGSNCIEIHHIGSTSVPGLAAKPIIDMIPVVLELSKVDSANAAMKALGY-------- 82
Cdd:PRK03333 213 RLVPADPSWPAQAQRIVARLKTAAGHKALRVDHIGSTAVPGLDAKDVIDIQVTVESLAVADELAEPLAAAGFprlpgitq 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282  83 -EAKGEYGIPFR---RYFQKGDNQRTHHAHIFEFGNPEIERHLKFRDWMRANPEDRVAYARLKQELAHQHPYDITAYCVG 158
Cdd:PRK03333 293 dTPKPDDPDPALwgkRLHASADPGRPVNLHVRVDGWPGQRFALLFRDWLRADPAARAEYLAVKRRAARRADGDTAAYADA 372

                        170
                 ....*....|..
gi 999734282 159 KEDFIAAIDRKA 170
Cdd:PRK03333 373 KEPWFLDAYPRA 384
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 209-318 1.31e-10

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 58.46  E-value: 1.31e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282 209 WTFEHEAHVHFVLSQGSDIIGYAHLQLWPHKRAALRIIVIDEEKRNHQYGGQFLALCEKWLKTQGYQSLHVESSPDALRF 288
Cdd:COG1246   21 YALEEEIGEFWVAEEDGEIVGCAALHPLDEDLAELRSLAVHPDYRGRGIGRRLLEALLAEARELGLKRLFLLTTSAAIHF 100

                         90       100       110
                 ....*....|....*....|....*....|.
gi 999734282 289 YRNNDYIDMPFDD-PDGYEGDARDTAVGKIL 318
Cdd:COG1246  101 YEKLGFEEIDKEDlPYAKVWQRDSVVMEKDL 131
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 214-294 1.27e-07

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 48.60  E-value: 1.27e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282  214 EAHVHFVLSQGSDIIGYAHLQLWPHKRAALRI-IVIDEEKRNHQYGGQFLALCEKWLKTQGYQSLHVESSPDALRFYRNN 292
Cdd:pfam13508   1 PGGRFFVAEDDGKIVGFAALLPLDDEGALAELrLAVHPEYRGQGIGRALLEAAEAAAKEGGIKLLELETTNRAAAFYEKL 80


                  ..
gi 999734282  293 DY 294
Cdd:pfam13508  81 GF 82
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 227-298 2.73e-06

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 46.20  E-value: 2.73e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 999734282 227 IIGYAHLQLWPHKRAALRIIVIDEEKRNHQYGGQFLALCEKWLKTQGYQSLHVESS---PDALRFYRNNDYIDMP 298
Cdd:COG0454   45 PIGFAGLRRLDDKVLELKRLYVLPEYRGKGIGKALLEALLEWARERGCTALELDTLdgnPAAIRFYERLGFKEIE 119
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 218-280 6.67e-05

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 40.34  E-value: 6.67e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 999734282 218 HFVLSQGSDIIGYAHLQLWPHKRAALRI--IVIDEEKRNHQYGGQFLALCEKWLKTQGYQSLHVE 280
Cdd:cd04301    1 FLVAEDDGEIVGFASLSPDGSGGDTAYIgdLAVLPEYRGKGIGSALLEAAEEEARERGAKRLRLE 65
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
178-309 1.76e-04

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 40.84  E-value: 1.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282 178 VKALTPREWDKVRHFRQFYFFDKAGLSDPYTWTFEHEAHVHFVLSQGSDIIGYAHLQLW----PHKRAALRIIVIDEEKR 253
Cdd:COG3153    1 IRPATPEDAEAIAALLRAAFGPGREAELVDRLREDPAAGLSLVAEDDGEIVGHVALSPVdidgEGPALLLGPLAVDPEYR 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 999734282 254 NHQYGGQFLALCEKWLKTQGYQSLHVESSPDALRFYRNNDYIDMPFDDPDGYEGDA 309
Cdd:COG3153   81 GQGIGRALMRAALEAARERGARAVVLLGDPSLLPFYERFGFRPAGELGLTLGPDEV 136
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
217-290 6.06e-04

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 39.40  E-value: 6.06e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 999734282 217 VHFVLSQGSDIIGYAHLQLWPHKRAALRIIVIDEEKRNHQYGGQFLALCEKWLKTQGYQSLHVESSPDALRFYR 290
Cdd:COG2153   35 RHLLAYDDGELVATARLLPPGDGEAKIGRVAVLPEYRGQGLGRALMEAAIEEARERGARRIVLSAQAHAVGFYE 108
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
213-290 9.97e-04

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 39.21  E-value: 9.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 999734282 213 HEAHVHFVLSQGSDIIGYAHLQLWpHKRAALRIIV-----IDEEKRNHQYGGQFLALCEKWLKTQGYQSLHVESSPD--- 284
Cdd:COG1247   49 APGRPVLVAEEDGEVVGFASLGPF-RPRPAYRGTAeesiyVDPDARGRGIGRALLEALIERARARGYRRLVAVVLADnea 127


                 ....*.
gi 999734282 285 ALRFYR 290
Cdd:COG1247  128 SIALYE 133
RpfG COG3437
Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains ...
 242-306 4.52e-03

Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains [Signal transduction mechanisms];


Pssm-ID: 442663 [Multi-domain]  Cd Length: 224  Bit Score: 37.84  E-value: 4.52e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 999734282 242 ALRIIVIDEEKRNhqyggqfLALCEKWLKTQGYQSLHVESSPDALRFYRNNDY------IDMPfdDPDGYE 306
Cdd:COG3437    6 APTVLIVDDDPEN-------LELLRQLLRTLGYDVVTAESGEEALELLLEAPPdlilldVRMP--GMDGFE 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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