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Conserved domains on  [gi|23336896|tpg|DAA00073|]
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TPA_exp: SF3b10 [Homo sapiens]

Protein Classification

splicing factor 3B subunit 5 family protein( domain architecture ID 10537590)

splicing factor 3B subunit 5 family protein such as eukaryotic splicing factor 3B subunit 5 (SF3B5, also known as SF3B10) that is involved in pre-mRNA splicing as the 10 kDa subunit of the splicing factor SF3B complex

Gene Ontology:  GO:1990935|GO:0003723|GO:0000124

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SF3b10 pfam07189
Splicing factor 3B subunit 10 (SF3b10); This family consists of several eukaryotic splicing ...
 3-77 8.54e-51

Splicing factor 3B subunit 10 (SF3b10); This family consists of several eukaryotic splicing factor 3B subunit 10 (SF3b10) proteins. SF3b10 is a 10 kDa subunit of the splicing factor SF3b. SF3b associates with the splicing factor SF3a and a 12S RNA unit to form the U2 small nuclear ribonucleoproteins complex. SF3b10 and SF3b14b are also thought to facilitate the interaction of U2 with the branch site.


:

Pssm-ID: 462114  Cd Length: 75  Bit Score: 153.47  E-value: 8.54e-51
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 23336896    3 DRYTIHSQLEHLQSKYIGTGHADTTKWEWLVNQHRDSYCSYMGHFDLLNYFAIAENESKARVRFNLMEKMLQPCG 77
Cdd:pfam07189  1 DKLRIQQQLEHLQSKYVGTGHADTTKEEWLTNIHRDTYASLVGHPPLLEYFAIAENESKARVRFNLLEKMIQPCG 75
 
Name Accession Description Interval E-value
SF3b10 pfam07189
Splicing factor 3B subunit 10 (SF3b10); This family consists of several eukaryotic splicing ...
 3-77 8.54e-51

Splicing factor 3B subunit 10 (SF3b10); This family consists of several eukaryotic splicing factor 3B subunit 10 (SF3b10) proteins. SF3b10 is a 10 kDa subunit of the splicing factor SF3b. SF3b associates with the splicing factor SF3a and a 12S RNA unit to form the U2 small nuclear ribonucleoproteins complex. SF3b10 and SF3b14b are also thought to facilitate the interaction of U2 with the branch site.


Pssm-ID: 462114  Cd Length: 75  Bit Score: 153.47  E-value: 8.54e-51
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 23336896    3 DRYTIHSQLEHLQSKYIGTGHADTTKWEWLVNQHRDSYCSYMGHFDLLNYFAIAENESKARVRFNLMEKMLQPCG 77
Cdd:pfam07189  1 DKLRIQQQLEHLQSKYVGTGHADTTKEEWLTNIHRDTYASLVGHPPLLEYFAIAENESKARVRFNLLEKMIQPCG 75
 
Name Accession Description Interval E-value
SF3b10 pfam07189
Splicing factor 3B subunit 10 (SF3b10); This family consists of several eukaryotic splicing ...
 3-77 8.54e-51

Splicing factor 3B subunit 10 (SF3b10); This family consists of several eukaryotic splicing factor 3B subunit 10 (SF3b10) proteins. SF3b10 is a 10 kDa subunit of the splicing factor SF3b. SF3b associates with the splicing factor SF3a and a 12S RNA unit to form the U2 small nuclear ribonucleoproteins complex. SF3b10 and SF3b14b are also thought to facilitate the interaction of U2 with the branch site.


Pssm-ID: 462114  Cd Length: 75  Bit Score: 153.47  E-value: 8.54e-51
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 23336896    3 DRYTIHSQLEHLQSKYIGTGHADTTKWEWLVNQHRDSYCSYMGHFDLLNYFAIAENESKARVRFNLMEKMLQPCG 77
Cdd:pfam07189  1 DKLRIQQQLEHLQSKYVGTGHADTTKEEWLTNIHRDTYASLVGHPPLLEYFAIAENESKARVRFNLLEKMIQPCG 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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