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Conserved domains on  [gi|285812538|tpg|DAA08437|]
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TPA: histidinol-phosphate transaminase [Saccharomyces cerevisiae S288C]

Protein Classification

histidinol-phosphate transaminase( domain architecture ID 11490209)

histidinol-phosphate transaminase is a pyridoxal phosphate (PLP)-dependent aminotransferase that catalyzes the reversible transfer of the amino group from glutamate to imidazole acetol-phosphate producing 2-oxoglutarate and histidinol phosphate

CATH:  3.40.640.10
EC:  2.6.1.9
Gene Symbol:  hisC
Gene Ontology:  GO:0004400|GO:0030170|GO:0000105
PubMed:  10800595
SCOP:  4000670

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
hisC TIGR01141
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ...
10-377 9.50e-140

histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]


:

Pssm-ID: 273467  Cd Length: 350  Bit Score: 401.65  E-value: 9.50e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   10 RPKIYNLEPYRC-ARDDFTEG-ILLDANENAHGPTPVELSK-----TNLHRYPDPHQLEFKTAMTKYRNktssyandpev 82
Cdd:TIGR01141   1 RPDIKNLSPYQPgARELGGDEvIKLNSNENPFGPPEKAKEAlraelKKLHRYPDPDPAELKQALADYYG----------- 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   83 kpLTADNLCLGVGSDESIDAIIRACCVPGkEKILVLPPTYSMYSVCANINDIEVVQCPLtvsDGSFQMDTEAVLTIlkND 162
Cdd:TIGR01141  70 --VDPEQILLGNGSDEIIDLLIRAFLEPG-DAVLVPPPTYSMYEISAKIHGAEVVKVPL---DEDGQLDLEDILVA--ID 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  163 SLIKLMFVTSPGNPTGAKIKTSLIEKVLQNW-DNGLVVVDEAYVDFCG-GSTAPLVTKYPNLVTLQTLSKSFGLAGIRLG 240
Cdd:TIGR01141 142 DKPKLVFLCSPNNPTGNLFSRGDIEAVLERTpGDALVVVDEAYGEFSGePSTLPLLAEYPNLIVLRTLSKAFGLAGLRIG 221
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  241 MTYATAELARILNAMKAPYNISSLASEYALKAVQDSNlkKMEATSKIINEEKMRLLKELTALDYVdDQYVGglDANFLLI 320
Cdd:TIGR01141 222 YAIANAEIIDALNKVRAPFNLSRLAQAAAIAALRDDD--FIEATVEEINAERERLYDGLKKLPGL-EVYPS--DANFVLI 296
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 285812538  321 RINGgdnvlAKKLYYQLATQSGVVVRFRGNELG-CSGCLRITVGTHEENTHLIKYFKE 377
Cdd:TIGR01141 297 RFPG-----DADALFEALLEKGIIVRDLNSYPGlLPNCLRITVGTREENDRFLAALRE 349
 
Name Accession Description Interval E-value
hisC TIGR01141
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ...
10-377 9.50e-140

histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]


Pssm-ID: 273467  Cd Length: 350  Bit Score: 401.65  E-value: 9.50e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   10 RPKIYNLEPYRC-ARDDFTEG-ILLDANENAHGPTPVELSK-----TNLHRYPDPHQLEFKTAMTKYRNktssyandpev 82
Cdd:TIGR01141   1 RPDIKNLSPYQPgARELGGDEvIKLNSNENPFGPPEKAKEAlraelKKLHRYPDPDPAELKQALADYYG----------- 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   83 kpLTADNLCLGVGSDESIDAIIRACCVPGkEKILVLPPTYSMYSVCANINDIEVVQCPLtvsDGSFQMDTEAVLTIlkND 162
Cdd:TIGR01141  70 --VDPEQILLGNGSDEIIDLLIRAFLEPG-DAVLVPPPTYSMYEISAKIHGAEVVKVPL---DEDGQLDLEDILVA--ID 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  163 SLIKLMFVTSPGNPTGAKIKTSLIEKVLQNW-DNGLVVVDEAYVDFCG-GSTAPLVTKYPNLVTLQTLSKSFGLAGIRLG 240
Cdd:TIGR01141 142 DKPKLVFLCSPNNPTGNLFSRGDIEAVLERTpGDALVVVDEAYGEFSGePSTLPLLAEYPNLIVLRTLSKAFGLAGLRIG 221
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  241 MTYATAELARILNAMKAPYNISSLASEYALKAVQDSNlkKMEATSKIINEEKMRLLKELTALDYVdDQYVGglDANFLLI 320
Cdd:TIGR01141 222 YAIANAEIIDALNKVRAPFNLSRLAQAAAIAALRDDD--FIEATVEEINAERERLYDGLKKLPGL-EVYPS--DANFVLI 296
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 285812538  321 RINGgdnvlAKKLYYQLATQSGVVVRFRGNELG-CSGCLRITVGTHEENTHLIKYFKE 377
Cdd:TIGR01141 297 RFPG-----DADALFEALLEKGIIVRDLNSYPGlLPNCLRITVGTREENDRFLAALRE 349
PLN03026 PLN03026
histidinol-phosphate aminotransferase; Provisional
7-380 4.05e-98

histidinol-phosphate aminotransferase; Provisional


Pssm-ID: 178597  Cd Length: 380  Bit Score: 296.61  E-value: 4.05e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   7 RIVRPKIYNLEPYRCARD----------DFTEGILLDANENAHGPTP-VELSKTNL---HRYPDPHQLEFKTAMTKYRNk 72
Cdd:PLN03026  22 SFIRKHILQLAPYQPILPfevlsaqlgrKPEDIVKLDANENPYGPPPeVLEALGNMkfpYVYPDPESRRLRAALAEDSG- 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  73 tssyandpevkpLTADNLCLGVGSDESIDAIIRACCVPGkEKILVLPPTYSMYSVCANINDIEVVQCPLTVSdgsFQMDT 152
Cdd:PLN03026 101 ------------LESENILVGCGADELIDLLMRCVLDPG-DKIIDCPPTFGMYVFDAAVNGAEVIKVPRTPD---FSLDV 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 153 EAVLTILKNDSlIKLMFVTSPGNPTGAKIKTSLIEKVLQNwdNGLVVVDEAYVDFCG-GSTAPLVTKYPNLVTLQTLSKS 231
Cdd:PLN03026 165 PRIVEAVETHK-PKLLFLTSPNNPDGSIISDDDLLKILEL--PILVVLDEAYIEFSTqESRMKWVKKYDNLIVLRTFSKR 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 232 FGLAGIRLGMTYATAELARILNAMKAPYNISSLASEYALKAVQdsNLKKMEATSKIINEEKMRLLKELTALDYVdDQYVG 311
Cdd:PLN03026 242 AGLAGLRVGYGAFPLSIIEYLWRAKQPYNVSVAAEVAACAALS--NPKYLEDVKNALVEERERLFGLLKEVPFL-EPYPS 318
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 285812538 312 glDANFLLIRINGGDNvlAKKLYYQLAtQSGVVVRFRGNElGCSGCLRITVGTHEENTHLIKYFKeTLY 380
Cdd:PLN03026 319 --DANFILCRVTSGRD--AKKLKEDLA-KMGVMVRHYNSK-ELKGYIRVSVGKPEHTDALMEALK-QLY 380
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
28-377 2.49e-91

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 277.78  E-value: 2.49e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  28 EGIL-LDANENAHGPTP-----VELSKTNLHRYPDPHQLEFKTAMTKYRNktssyandpevkpLTADNLCLGVGSDESID 101
Cdd:COG0079   13 EDIIkLSSNENPYGPPPkvleaIAAALDALNRYPDPDATALREALAEYYG-------------VPPEQVLVGNGSDELIQ 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 102 AIIRACCVPGKEkILVLPPTYSMYSVCANINDIEVVQCPLtvsDGSFQMDTEAVLTILKNDslIKLMFVTSPGNPTGAKI 181
Cdd:COG0079   80 LLARAFLGPGDE-VLVPEPTFSEYPIAARAAGAEVVEVPL---DEDFSLDLDALLAAITER--TDLVFLCNPNNPTGTLL 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 182 KTSLIEKVLQNW-DNGLVVVDEAYVDFCGG--STAPLVTKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARILNAMKAP 258
Cdd:COG0079  154 PREELEALLEALpADGLVVVDEAYAEFVPEedSALPLLARYPNLVVLRTFSKAYGLAGLRLGYAIASPELIAALRRVRGP 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 259 YNISSLASEYALKAVQDSNLkkMEATSKIINEEKMRLLKELTALDYvddQYVGGlDANFLLIRINGGdnvlAKKLYYQLA 338
Cdd:COG0079  234 WNVNSLAQAAALAALEDRAY--LEETRARLRAERERLAAALRALGL---TVYPS-QANFVLVRVPED----AAELFEALL 303
                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 285812538 339 TQsGVVVRfRGNELGCSGCLRITVGTHEENTHLIKYFKE 377
Cdd:COG0079  304 ER-GILVR-DFSSFGLPDYLRITVGTPEENDRLLAALKE 340
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
27-375 2.80e-80

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 249.91  E-value: 2.80e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   27 TEGILLDANENAHGPTPV-------ELSKTNLHRYPDPH-QLEFKTAMTKYRNKTSSYANDPEvkpltaDNLCLGVGSDE 98
Cdd:pfam00155   1 TDKINLGSNEYLGDTLPAvakaekdALAGGTRNLYGPTDgHPELREALAKFLGRSPVLKLDRE------AAVVFGSGAGA 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   99 SIDAIIRACCVPGkEKILVLPPTYSMYSVCANINDIEVVQCPLTVSDGsFQMDTEAVLTILKndSLIKLMFVTSPGNPTG 178
Cdd:pfam00155  75 NIEALIFLLANPG-DAILVPAPTYASYIRIARLAGGEVVRYPLYDSND-FHLDFDALEAALK--EKPKVVLHTSPHNPTG 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  179 AKIKTSLIEKVLQNWD--NGLVVVDEAYVDFCGG-----STAPLVTKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARI 251
Cdd:pfam00155 151 TVATLEELEKLLDLAKehNILLLVDEAYAGFVFGspdavATRALLAEGPNLLVVGSFSKAFGLAGWRVGYILGNAAVISQ 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  252 LNAMKAPYNISSLASEYALKAVQDSNLK--KMEATSKIINEEKMRLLKELTALDYvddqYVGGLDANFLLIRinGGDNVL 329
Cdd:pfam00155 231 LRKLARPFYSSTHLQAAAAAALSDPLLVasELEEMRQRIKERRDYLRDGLQAAGL----SVLPSQAGFFLLT--GLDPET 304
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 285812538  330 AKKLYYQLATQSGVVVRfRGNELGCSGCLRITV--GTHEENTHLIKYF 375
Cdd:pfam00155 305 AKELAQVLLEEVGVYVT-PGSSPGVPGWLRITVagGTEEELEELLEAI 351
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
30-377 7.91e-64

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 207.58  E-value: 7.91e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  30 ILLDANENAHGPTP--------VELSKTNLHRYPDPHQLEFKTAMtkyrnktSSYANDPEVKPLTADNLCLGVGSDESID 101
Cdd:cd00609    1 IDLSIGEPDFPPPPevlealaaAALRAGLLGYYPDPGLPELREAI-------AEWLGRRGGVDVPPEEIVVTNGAQEALS 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 102 AIIRACCVPGKEkILVLPPTYSMYSVCANINDIEVVQCPLTvSDGSFQMDTEAVLTILKNDslIKLMFVTSPGNPTGAKI 181
Cdd:cd00609   74 LLLRALLNPGDE-VLVPDPTYPGYEAAARLAGAEVVPVPLD-EEGGFLLDLELLEAAKTPK--TKLLYLNNPNNPTGAVL 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 182 KTSLIEKVLQ--NWDNGLVVVDEAYVDFCGG----STAPLVTKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARILNAM 255
Cdd:cd00609  150 SEEELEELAElaKKHGILIISDEAYAELVYDgeppPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLERLKK 229
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 256 KAPY--NISSLASEYALKAVQDSNLKKMEATSKIINEEKMRLLKELTALDYVDDQYVGGldANFLLIRINGGDnvlAKKL 333
Cdd:cd00609  230 LLPYttSGPSTLSQAAAAAALDDGEEHLEELRERYRRRRDALLEALKELGPLVVVKPSG--GFFLWLDLPEGD---DEEF 304
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*.
gi 285812538 334 YYQLATQSGVVVRFRGN-ELGCSGCLRITVGT-HEENTHLIKYFKE 377
Cdd:cd00609  305 LERLLLEAGVVVRPGSAfGEGGEGFVRLSFATpEEELEEALERLAE 350
 
Name Accession Description Interval E-value
hisC TIGR01141
histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; ...
10-377 9.50e-140

histidinol-phosphate aminotransferase; Alternate names: histidinol-phosphate transaminase; imidazole acetol-phosphate transaminase Histidinol-phosphate aminotransferase is a pyridoxal-phosphate dependent enzyme. [Amino acid biosynthesis, Histidine family]


Pssm-ID: 273467  Cd Length: 350  Bit Score: 401.65  E-value: 9.50e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   10 RPKIYNLEPYRC-ARDDFTEG-ILLDANENAHGPTPVELSK-----TNLHRYPDPHQLEFKTAMTKYRNktssyandpev 82
Cdd:TIGR01141   1 RPDIKNLSPYQPgARELGGDEvIKLNSNENPFGPPEKAKEAlraelKKLHRYPDPDPAELKQALADYYG----------- 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   83 kpLTADNLCLGVGSDESIDAIIRACCVPGkEKILVLPPTYSMYSVCANINDIEVVQCPLtvsDGSFQMDTEAVLTIlkND 162
Cdd:TIGR01141  70 --VDPEQILLGNGSDEIIDLLIRAFLEPG-DAVLVPPPTYSMYEISAKIHGAEVVKVPL---DEDGQLDLEDILVA--ID 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  163 SLIKLMFVTSPGNPTGAKIKTSLIEKVLQNW-DNGLVVVDEAYVDFCG-GSTAPLVTKYPNLVTLQTLSKSFGLAGIRLG 240
Cdd:TIGR01141 142 DKPKLVFLCSPNNPTGNLFSRGDIEAVLERTpGDALVVVDEAYGEFSGePSTLPLLAEYPNLIVLRTLSKAFGLAGLRIG 221
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  241 MTYATAELARILNAMKAPYNISSLASEYALKAVQDSNlkKMEATSKIINEEKMRLLKELTALDYVdDQYVGglDANFLLI 320
Cdd:TIGR01141 222 YAIANAEIIDALNKVRAPFNLSRLAQAAAIAALRDDD--FIEATVEEINAERERLYDGLKKLPGL-EVYPS--DANFVLI 296
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 285812538  321 RINGgdnvlAKKLYYQLATQSGVVVRFRGNELG-CSGCLRITVGTHEENTHLIKYFKE 377
Cdd:TIGR01141 297 RFPG-----DADALFEALLEKGIIVRDLNSYPGlLPNCLRITVGTREENDRFLAALRE 349
PLN03026 PLN03026
histidinol-phosphate aminotransferase; Provisional
7-380 4.05e-98

histidinol-phosphate aminotransferase; Provisional


Pssm-ID: 178597  Cd Length: 380  Bit Score: 296.61  E-value: 4.05e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   7 RIVRPKIYNLEPYRCARD----------DFTEGILLDANENAHGPTP-VELSKTNL---HRYPDPHQLEFKTAMTKYRNk 72
Cdd:PLN03026  22 SFIRKHILQLAPYQPILPfevlsaqlgrKPEDIVKLDANENPYGPPPeVLEALGNMkfpYVYPDPESRRLRAALAEDSG- 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  73 tssyandpevkpLTADNLCLGVGSDESIDAIIRACCVPGkEKILVLPPTYSMYSVCANINDIEVVQCPLTVSdgsFQMDT 152
Cdd:PLN03026 101 ------------LESENILVGCGADELIDLLMRCVLDPG-DKIIDCPPTFGMYVFDAAVNGAEVIKVPRTPD---FSLDV 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 153 EAVLTILKNDSlIKLMFVTSPGNPTGAKIKTSLIEKVLQNwdNGLVVVDEAYVDFCG-GSTAPLVTKYPNLVTLQTLSKS 231
Cdd:PLN03026 165 PRIVEAVETHK-PKLLFLTSPNNPDGSIISDDDLLKILEL--PILVVLDEAYIEFSTqESRMKWVKKYDNLIVLRTFSKR 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 232 FGLAGIRLGMTYATAELARILNAMKAPYNISSLASEYALKAVQdsNLKKMEATSKIINEEKMRLLKELTALDYVdDQYVG 311
Cdd:PLN03026 242 AGLAGLRVGYGAFPLSIIEYLWRAKQPYNVSVAAEVAACAALS--NPKYLEDVKNALVEERERLFGLLKEVPFL-EPYPS 318
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 285812538 312 glDANFLLIRINGGDNvlAKKLYYQLAtQSGVVVRFRGNElGCSGCLRITVGTHEENTHLIKYFKeTLY 380
Cdd:PLN03026 319 --DANFILCRVTSGRD--AKKLKEDLA-KMGVMVRHYNSK-ELKGYIRVSVGKPEHTDALMEALK-QLY 380
HisC COG0079
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ...
28-377 2.49e-91

Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 439849 [Multi-domain]  Cd Length: 341  Bit Score: 277.78  E-value: 2.49e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  28 EGIL-LDANENAHGPTP-----VELSKTNLHRYPDPHQLEFKTAMTKYRNktssyandpevkpLTADNLCLGVGSDESID 101
Cdd:COG0079   13 EDIIkLSSNENPYGPPPkvleaIAAALDALNRYPDPDATALREALAEYYG-------------VPPEQVLVGNGSDELIQ 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 102 AIIRACCVPGKEkILVLPPTYSMYSVCANINDIEVVQCPLtvsDGSFQMDTEAVLTILKNDslIKLMFVTSPGNPTGAKI 181
Cdd:COG0079   80 LLARAFLGPGDE-VLVPEPTFSEYPIAARAAGAEVVEVPL---DEDFSLDLDALLAAITER--TDLVFLCNPNNPTGTLL 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 182 KTSLIEKVLQNW-DNGLVVVDEAYVDFCGG--STAPLVTKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARILNAMKAP 258
Cdd:COG0079  154 PREELEALLEALpADGLVVVDEAYAEFVPEedSALPLLARYPNLVVLRTFSKAYGLAGLRLGYAIASPELIAALRRVRGP 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 259 YNISSLASEYALKAVQDSNLkkMEATSKIINEEKMRLLKELTALDYvddQYVGGlDANFLLIRINGGdnvlAKKLYYQLA 338
Cdd:COG0079  234 WNVNSLAQAAALAALEDRAY--LEETRARLRAERERLAAALRALGL---TVYPS-QANFVLVRVPED----AAELFEALL 303
                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 285812538 339 TQsGVVVRfRGNELGCSGCLRITVGTHEENTHLIKYFKE 377
Cdd:COG0079  304 ER-GILVR-DFSSFGLPDYLRITVGTPEENDRLLAALKE 340
Aminotran_1_2 pfam00155
Aminotransferase class I and II;
27-375 2.80e-80

Aminotransferase class I and II;


Pssm-ID: 395103 [Multi-domain]  Cd Length: 351  Bit Score: 249.91  E-value: 2.80e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   27 TEGILLDANENAHGPTPV-------ELSKTNLHRYPDPH-QLEFKTAMTKYRNKTSSYANDPEvkpltaDNLCLGVGSDE 98
Cdd:pfam00155   1 TDKINLGSNEYLGDTLPAvakaekdALAGGTRNLYGPTDgHPELREALAKFLGRSPVLKLDRE------AAVVFGSGAGA 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   99 SIDAIIRACCVPGkEKILVLPPTYSMYSVCANINDIEVVQCPLTVSDGsFQMDTEAVLTILKndSLIKLMFVTSPGNPTG 178
Cdd:pfam00155  75 NIEALIFLLANPG-DAILVPAPTYASYIRIARLAGGEVVRYPLYDSND-FHLDFDALEAALK--EKPKVVLHTSPHNPTG 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  179 AKIKTSLIEKVLQNWD--NGLVVVDEAYVDFCGG-----STAPLVTKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARI 251
Cdd:pfam00155 151 TVATLEELEKLLDLAKehNILLLVDEAYAGFVFGspdavATRALLAEGPNLLVVGSFSKAFGLAGWRVGYILGNAAVISQ 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  252 LNAMKAPYNISSLASEYALKAVQDSNLK--KMEATSKIINEEKMRLLKELTALDYvddqYVGGLDANFLLIRinGGDNVL 329
Cdd:pfam00155 231 LRKLARPFYSSTHLQAAAAAALSDPLLVasELEEMRQRIKERRDYLRDGLQAAGL----SVLPSQAGFFLLT--GLDPET 304
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 285812538  330 AKKLYYQLATQSGVVVRfRGNELGCSGCLRITV--GTHEENTHLIKYF 375
Cdd:pfam00155 305 AKELAQVLLEEVGVYVT-PGSSPGVPGWLRITVagGTEEELEELLEAI 351
AAT_like cd00609
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ...
30-377 7.91e-64

Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.


Pssm-ID: 99734 [Multi-domain]  Cd Length: 350  Bit Score: 207.58  E-value: 7.91e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  30 ILLDANENAHGPTP--------VELSKTNLHRYPDPHQLEFKTAMtkyrnktSSYANDPEVKPLTADNLCLGVGSDESID 101
Cdd:cd00609    1 IDLSIGEPDFPPPPevlealaaAALRAGLLGYYPDPGLPELREAI-------AEWLGRRGGVDVPPEEIVVTNGAQEALS 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 102 AIIRACCVPGKEkILVLPPTYSMYSVCANINDIEVVQCPLTvSDGSFQMDTEAVLTILKNDslIKLMFVTSPGNPTGAKI 181
Cdd:cd00609   74 LLLRALLNPGDE-VLVPDPTYPGYEAAARLAGAEVVPVPLD-EEGGFLLDLELLEAAKTPK--TKLLYLNNPNNPTGAVL 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 182 KTSLIEKVLQ--NWDNGLVVVDEAYVDFCGG----STAPLVTKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARILNAM 255
Cdd:cd00609  150 SEEELEELAElaKKHGILIISDEAYAELVYDgeppPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLERLKK 229
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 256 KAPY--NISSLASEYALKAVQDSNLKKMEATSKIINEEKMRLLKELTALDYVDDQYVGGldANFLLIRINGGDnvlAKKL 333
Cdd:cd00609  230 LLPYttSGPSTLSQAAAAAALDDGEEHLEELRERYRRRRDALLEALKELGPLVVVKPSG--GFFLWLDLPEGD---DEEF 304
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*.
gi 285812538 334 YYQLATQSGVVVRFRGN-ELGCSGCLRITVGT-HEENTHLIKYFKE 377
Cdd:cd00609  305 LERLLLEAGVVVRPGSAfGEGGEGFVRLSFATpEEELEEALERLAE 350
PRK02610 PRK02610
histidinol-phosphate transaminase;
9-382 4.89e-53

histidinol-phosphate transaminase;


Pssm-ID: 235053  Cd Length: 374  Bit Score: 180.30  E-value: 4.89e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   9 VRPKIYNLEPYRCARDDFTEGIL-----LDANENAHGpTPVELsKTNL----------HRYPDPHQLEFKTAMTKYRNKT 73
Cdd:PRK02610   5 LRSDLAQLKAYHPHPSGDADDAViqldrLDTNEFPYD-LPPDL-KQKLawlyqqgiesNRYPDGGHEALKQAIAEYVNES 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  74 SSYANDPevkplTADNLCLGVGSDESIDAIIRACCVPGKEKILVLPPTYSMYSVCANINDIEVVQCPLTVSDgsFQMDTE 153
Cdd:PRK02610  83 AAGSSQI-----TPANISVGNGSDELIRSLLIATCLGGEGSILVAEPTFSMYGILAQTLGIPVVRVGRDPET--FEIDLA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 154 AVLTILKNDSL--IKLMFVTSPGNPTGAKIKTSLIEKVLQNWDNGLVVVDEAYVDFCGGSTAPLVTKYPNLVTLQTLSKS 231
Cdd:PRK02610 156 AAQSAIEQTQNppVRVVFVVHPNSPTGNPLTAAELEWLRSLPEDILVVIDEAYFEFSQTTLVGELAQHPNWVILRTFSKA 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 232 FGLAGIRLGMTYATAELARILNAMKAPYNISSLASEYALKAVQDSNLkKMEATSKIINeEKMRLLKeltALDYVDDQYVG 311
Cdd:PRK02610 236 FRLAAHRVGYAIGHPELIAVLEKVRLPYNLPSFSQLAAQLALEHRQE-LLAAIPEILQ-ERDRLYQ---ALQELPQLRVW 310
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 285812538 312 GLDANFLLIRINGGDNVLAkkLYYQLATQsGVVVRfrgnelGCSGCLRITVGTHEENTHLIKYFKETLYKL 382
Cdd:PRK02610 311 PSAANFLYLRLSQDAALAA--LHQALKAQ-GTLVR------HTGGGLRITIGTPEENQRTLERLQAALTQL 372
PRK03317 PRK03317
histidinol-phosphate aminotransferase; Provisional
30-369 1.47e-41

histidinol-phosphate aminotransferase; Provisional


Pssm-ID: 235115  Cd Length: 368  Bit Score: 149.63  E-value: 1.47e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  30 ILLDANENAHGPTP---------VELSKTNLHRYPDPHQLEFKTAMTKYRNKTSSYandpevkPLTADNLCLGVGSDESI 100
Cdd:PRK03317  29 VRLNTNENPYPPSPalvadiaeaVAEAAAGLNRYPDRDAVALRADLAAYLTAQTGV-------GLTVENVWAANGSNEIL 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 101 DAIIRACCVPGKeKILVLPPTYSMYSVCANINDIEVVQCPltvSDGSFQMDTEAVLTILKN---DslikLMFVTSPGNPT 177
Cdd:PRK03317 102 QQLLQAFGGPGR-TALGFVPSYSMHPIIARGTHTEWVEGP---RAADFTLDVDAAVAAIAEhrpD----VVFLTSPNNPT 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 178 GAKIKTSLIEKVLQNWDnGLVVVDEAYVDFC--GGSTA-PLVTKYPNLVTLQTLSKSFGLAGIRLGmtYATAELArILNA 254
Cdd:PRK03317 174 GTALPLDDVEAILDAAP-GIVVVDEAYAEFRrsGTPSAlTLLPEYPRLVVSRTMSKAFAFAGGRLG--YLAAAPA-VVDA 249
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 255 M---KAPYNISSLASEYALKAVQ--DSNLKKMEAtskiINEEKMRLLKELTALDYvddqYVGGLDANFLLIringGDNVL 329
Cdd:PRK03317 250 LrlvRLPYHLSAVTQAAARAALRhaDELLASVAA----LRAERDRVVAWLRELGL----RVAPSDANFVLF----GRFAD 317
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 285812538 330 AKKLYYQLATQsGVVVRfrgnELGCSGCLRITVGTHEENT 369
Cdd:PRK03317 318 RHAVWQGLLDR-GVLIR----DVGIPGWLRVTIGTPEEND 352
PRK03321 PRK03321
putative aminotransferase; Provisional
9-373 2.84e-36

putative aminotransferase; Provisional


Pssm-ID: 179559  Cd Length: 352  Bit Score: 135.09  E-value: 2.84e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   9 VRPKIYNLEPYRCARDdFTEGILLDANENAHGPTP-----VELSKTNLHRYPDPHQLEFKTAMTKYRNktssyandpevk 83
Cdd:PRK03321   5 LRPDLAGIPAYVPGKT-VPGAIKLSSNETPFGPLPsvraaIARAAAGVNRYPDMGAVELRAALAEHLG------------ 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  84 pLTADNLCLGVGSDESIDAIIRACCVPGKEkilVLPP--TYSMYSVCANINDIEVVQCPLTvSDGSFqmDTEAVLTILKN 161
Cdd:PRK03321  72 -VPPEHVAVGCGSVALCQQLVQATAGPGDE---VIFAwrSFEAYPILVQVAGATPVQVPLT-PDHTH--DLDAMAAAITD 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 162 DSliKLMFVTSPGNPTGAKIKTSLIEKVLQNW-DNGLVVVDEAYVDFCGGSTAP----LVTKYPNLVTLQTLSKSFGLAG 236
Cdd:PRK03321 145 RT--RLIFVCNPNNPTGTVVTPAELARFLDAVpADVLVVLDEAYVEYVRDDDVPdgleLVRDHPNVVVLRTFSKAYGLAG 222
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 237 IRLGMTYATAELARILNAMKAPYNISSLASEYALK--AVQDSNLKKMEATSKiineEKMRLLKELTALDYVddqyVGGLD 314
Cdd:PRK03321 223 LRVGYAVGHPEVIAALRKVAVPFSVNSLAQAAAIAslAAEDELLERVDAVVA----ERDRVRAALRAAGWT----VPPSQ 294
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 285812538 315 ANFLLIRINGGDNVLAKKLyyqlaTQSGVVVRFRGNElGcsgcLRITVGTHEENTHLIK 373
Cdd:PRK03321 295 ANFVWLPLGERTADFAAAA-----AEAGVVVRPFAGE-G----VRVTIGAPEENDAFLR 343
PRK05166 PRK05166
histidinol-phosphate transaminase;
7-379 1.72e-29

histidinol-phosphate transaminase;


Pssm-ID: 179950  Cd Length: 371  Bit Score: 117.16  E-value: 1.72e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   7 RIVRPKIYNLEPYRC--------ARDDFTEGILLDANENAHGPTPVELSK-----TNLHRYPDPHQLEFKTAMTKyrnKT 73
Cdd:PRK05166   8 SLARAEVRPLPPYNAgltieevrARYGVPRIAKLGSNENPLGPSPAVRRAfadiaELLRLYPDPQGRALREAIAA---RT 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  74 SsyandpevkpLTADNLCLGVGSDESIDAIIRACCVPGkEKILVLPPTYSMYSVCANINDIEVVQCPLTvSDGSFQMDte 153
Cdd:PRK05166  85 G----------VPADRIILGNGSEDLIAVICRAVLRPG-DRVVTLYPSFPLHEDYPTMMGARVERVTVT-PDLGFDLD-- 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 154 AVLTILKNDSliKLMFVTSPGNPTGAKIKTSLIEKVLQNWD-NGLVVVDEAYVDFCGGSTAP-----LVTKYPNLVTLQT 227
Cdd:PRK05166 151 ALCAAVARAP--RMLMFSNPSNPVGSWLTADQLARVLDATPpETLIVVDEAYAEYAAGDDYPsaltlLKARGLPWIVLRT 228
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 228 LSKSFGLAGIRLGMTYAT-AELARILNAMKAPYNISSLASEYALKAVQD-SNLKKMEATSKIineEKMRLLKELTALDYv 305
Cdd:PRK05166 229 FSKAYGLAGLRVGYGLVSdPELVGLLDRVRTPFNVNGAAQAAALAALDDeEHLAKGVALALA---ERERLKKELAEMGY- 304
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 285812538 306 ddqYVGGLDANFLLIRINGGDNVLAKKLYYQlatqsGVVVRfRGNELGCSGCLRITVGTHEENTHLIKYFKETL 379
Cdd:PRK05166 305 ---RIAPSRANFLFFDARRPASAVAEALLRQ-----GVIVK-PWKQPGFETFIRVSIGSPEENDHFVAALDKVL 369
AspB COG0436
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ...
41-275 6.12e-23

Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis


Pssm-ID: 440205 [Multi-domain]  Cd Length: 387  Bit Score: 99.05  E-value: 6.12e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  41 PTP-------VELSKTNLHRYPDPH-QLEFKTAMTKYrnktssYANDPEVkPLTADNLCLGVGSDESIDAIIRACCVPGK 112
Cdd:COG0436   43 PTPdhireaaIEALDDGVTGYTPSAgIPELREAIAAY------YKRRYGV-DLDPDEILVTNGAKEALALALLALLNPGD 115
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 113 EkILVLPPTYSMYSVCANINDIEVVQCPLTVSDGsFQMDTEAVL-TILKNdslIKLMFVTSPGNPTGAKIKTSLIEKVLQ 191
Cdd:COG0436  116 E-VLVPDPGYPSYRAAVRLAGGKPVPVPLDEENG-FLPDPEALEaAITPR---TKAIVLNSPNNPTGAVYSREELEALAE 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 192 nW--DNGLVVV-DEAYVDFC-GGSTAPLVTKYP----NLVTLQTLSKSFGLAGIRLGMTYATAELARILNAMKA-----P 258
Cdd:COG0436  191 -LarEHDLLVIsDEIYEELVyDGAEHVSILSLPglkdRTIVINSFSKSYAMTGWRIGYAVGPPELIAALLKLQSnltscA 269
                        250
                 ....*....|....*..
gi 285812538 259 YNISSLASEYALKAVQD 275
Cdd:COG0436  270 PTPAQYAAAAALEGPQD 286
PRK09105 PRK09105
pyridoxal phosphate-dependent aminotransferase;
29-266 7.98e-20

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181651  Cd Length: 370  Bit Score: 89.72  E-value: 7.98e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  29 GILLDANENAHGPTPVEL-----SKTNLHRYPDPHQLEFKTAMTKyrnktssyandpeVKPLTADNLCLGVGSDESIDAI 103
Cdd:PRK09105  45 AVFLNANECPLGPSPAARdaaarSAALSGRYDLELEDDLRTLFAA-------------QEGLPADHVMAYAGSSEPLNYA 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 104 IRACCvpGKEKILVLP-PTYSMYSVCANINDIEVVQCPLTvsdGSFQMDTEAVLTILKNDSLIklmFVTSPGNPTGAKIK 182
Cdd:PRK09105 112 VLAFT--SPTAGLVTAdPTYEAGWRAADAQGAPVAKVPLR---ADGAHDVKAMLAADPNAGLI---YICNPNNPTGTVTP 183
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 183 TSLIEKVLQNWDNG-LVVVDEAYVDFCGG-STAPLVTKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARIL-----NAM 255
Cdd:PRK09105 184 RADIEWLLANKPAGsVLLVDEAYIHFSDApSVVDLVAQRKDLIVLRTFSKLYGMAGMRLGLAAARPDLLAKLarfghNPL 263
                        250
                 ....*....|.
gi 285812538 256 KAPYNISSLAS 266
Cdd:PRK09105 264 PVPAAAAGLAS 274
PRK08354 PRK08354
putative aminotransferase; Provisional
112-378 1.19e-18

putative aminotransferase; Provisional


Pssm-ID: 169399  Cd Length: 311  Bit Score: 85.55  E-value: 1.19e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 112 KEKILVLP-PTYSMYSVCANINDIEVVQCPLtvsdgsfqmDTEAVLTILKNDSLIklmFVTSPGNPTGAKIKTS----LI 186
Cdd:PRK08354  76 RDRKVIIPrHTYGEYERVARFFAARIIKGPN---------DPEKLEELVERNSVV---FFCNPNNPDGKFYNFKelkpLL 143
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 187 EKVLQNwdNGLVVVDEAYVDFCGGSTAPlvtKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARilnAMKAPYNISSLAs 266
Cdd:PRK08354 144 DAVEDR--NALLILDEAFIDFVKKPESP---EGENIIKLRTFTKSYGLPGIRVGYVKGFEEAFR---SVRMPWSIGSTG- 214
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 267 eYA-LKAVQDSNLKKMEATSKIINEEKMRLLKELtaldYVDDqyvgglDANFLLIRINGGDNVLakklyyQLATQSGVVV 345
Cdd:PRK08354 215 -YAfLEFLIEDDFEHLRKTMPLIWREKERFEKAL----YVKS------DANFFIKDVGDAEKFV------EFLKRNGILV 277
                        250       260       270
                 ....*....|....*....|....*....|...
gi 285812538 346 RfRGNELGCSGCLRITVGTHEENTHLIKYFKET 378
Cdd:PRK08354 278 R-DCTSFGLPGYIRFSVRDREENEKLIRALREW 309
PRK06425 PRK06425
histidinol-phosphate aminotransferase; Validated
111-372 9.68e-16

histidinol-phosphate aminotransferase; Validated


Pssm-ID: 102370  Cd Length: 332  Bit Score: 77.59  E-value: 9.68e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 111 GKEKILVLPPTYSMYSVCANINDIEVVQCPLTvsdgsfqmdteavltILKNDSLI------KLMFVTSPGNPTGAKIKTS 184
Cdd:PRK06425  78 NVGNIIIVEPNFNEYKGYAFTHGIRISALPFN---------------LINNNPEIlnnynfDLIFIVSPDNPLGNLISRD 142
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 185 LIEKV--LQNWDNGLVVVDEAYVDFC---GGSTAPLVTKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARILNAMKAPY 259
Cdd:PRK06425 143 SLLTIseICRKKGALLFIDEAFIDFVpnrAEEDVLLNRSYGNVIIGRSLTKILGIPSLRIGYIATDDYNMKISRKITEPW 222
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 260 NIsslaSEYALKAVQDSNLKKMEATS-KIINEEKMRLLKELTALDYvddQYVGGLDANFLLIRINGGDNvlakklYYQLA 338
Cdd:PRK06425 223 SV----CDPAIDFIRSIDLDYVAKHSlDIMENERSYLINNLEAMGF---RAAGDPSANFITFMIPDAHD------FYSYL 289
                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 285812538 339 TQSGVVVRFRgNELGCSG--CLRITVGTHEENTHLI 372
Cdd:PRK06425 290 LKNGILVRLL-DDYECLGeqYIRIAIRRRSFNIKLV 324
PRK08153 PRK08153
pyridoxal phosphate-dependent aminotransferase;
32-367 3.74e-14

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181255  Cd Length: 369  Bit Score: 73.11  E-value: 3.74e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  32 LDANENAHGPTP-----VELSKTNLHRYPDPHQLEFKTAMtkyrnktssyANDPEVKPltaDNLCLGVGSDESIDAIIRA 106
Cdd:PRK08153  37 IGANESGFGPSPsviaaMREAAAEIWKYGDPENHDLRHAL----------AAHHGVAP---ENIMVGEGIDGLLGLIVRL 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 107 CCVPGKEKILVLP--PTYSmYSVCAN---------INDIEvvqcpltvsdgsfqmDTEAVLTILKNDSlIKLMFVTSPGN 175
Cdd:PRK08153 104 YVEPGDPVVTSLGayPTFN-YHVAGFggrlvtvpyRDDRE---------------DLDALLDAARREN-APLVYLANPDN 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 176 PTGAKIKTSLIEKVLQNWDNG-LVVVDEAYVDFCGGSTAPLV-TKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARILN 253
Cdd:PRK08153 167 PMGSWHPAADIVAFIEALPETtLLVLDEAYCETAPAGAAPPIdTDDPNVIRMRTFSKAYGLAGARVGYAIGAPGTIKAFD 246
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 254 AMKAPYNISSLASEYALKAVQDSNLKKmEATSKIIN--EEKMRLLKE--LTALDYVddqyvggldANFLLIRInGGDNVL 329
Cdd:PRK08153 247 KVRNHFGMNRIAQAAALAALKDQAYLA-EVVGKIAAarDRIAAIARAngLTPLPSA---------TNFVAIDC-GRDGAF 315
                        330       340       350
                 ....*....|....*....|....*....|....*...
gi 285812538 330 AKKLYYQLaTQSGVVVRFRGNElGCSGCLRITVGTHEE 367
Cdd:PRK08153 316 ARAVLDGL-IARDIFVRMPGVA-PLDRCIRVSCGPDEE 351
PRK07908 PRK07908
threonine-phosphate decarboxylase;
143-379 3.03e-12

threonine-phosphate decarboxylase;


Pssm-ID: 236128  Cd Length: 349  Bit Score: 66.95  E-value: 3.03e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 143 VSDGSFQMDTEAV-----LTILKNdsliklmfvtsPGNPTGAKIKTSLIEKVLQNWDngLVVVDEAYVDFCGGSTAPLV- 216
Cdd:PRK07908 124 VLDPPFRLDPAAVpddadLVVIGN-----------PTNPTSVLHPAEQLLALRRPGR--ILVVDEAFADAVPGEPESLAg 190
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 217 TKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARILNAMKAPYNISSLASEYALKAVQDSNLKKMEATSKIINEEKMRLL 296
Cdd:PRK07908 191 DDLPGVLVLRSLTKTWSLAGLRVGYALGAPDVLARLTRGRAHWPVGTLQLEAIAACCAPRAVAEAAADAARLAADRAEMV 270
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 297 KELTALDYvddQYVGGLDANFLLIRINGGDNVLAkklyyQLATQsGVVVRfRGNE---LGcSGCLRITVGTHEENTHLIK 373
Cdd:PRK07908 271 AGLRAVGA---RVVDPAAAPFVLVRVPDAELLRK-----RLRER-GIAVR-RGDTfpgLD-PDYLRLAVRPRAEVPVLVQ 339

                 ....*.
gi 285812538 374 YFKETL 379
Cdd:PRK07908 340 ALAEIL 345
MalY COG1168
Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor ...
99-263 8.58e-12

Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440782  Cd Length: 387  Bit Score: 65.88  E-value: 8.58e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  99 SIDAIIRACCVPGkEKILVLPPTY-SMYSVCANiNDIEVVQCPLTVSDGSFQMDTEAVLTILKNDslIKLMFVTSPGNPT 177
Cdd:COG1168   99 GLALAIRAFTEPG-DGVLIQTPVYpPFFKAIEN-NGRELVENPLILEDGRYRIDFDDLEAKLDPG--VKLLLLCNPHNPT 174
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 178 G--------AKIktslIEKVLQNwdNGLVVVDEAYVDFC-GGST----APLVTKY-PNLVTLQTLSKSFGLAGIRLGMTY 243
Cdd:COG1168  175 GrvwtreelERL----AELCERH--DVLVISDEIHADLVlPGHKhtpfASLSEEAaDRTITLTSPSKTFNLAGLKASYAI 248
                        170       180
                 ....*....|....*....|.
gi 285812538 244 AT-AELARILNAMKAPYNISS 263
Cdd:COG1168  249 IPnPALRARFARALEGLGLPS 269
PRK06225 PRK06225
pyridoxal phosphate-dependent aminotransferase;
79-324 2.56e-11

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235749 [Multi-domain]  Cd Length: 380  Bit Score: 64.39  E-value: 2.56e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  79 DPEVKPLTADNLCLG-------VGSDESIDAIIRACCVPGKEkiLVLP-PTYSMYSVCANINDIEVVQCPLTVSDGSFQM 150
Cdd:PRK06225  68 FPELRELILKDLGLDddealitAGATESLYLVMRAFLSPGDN--AVTPdPGYLIIDNFASRFGAEVIEVPIYSEECNYKL 145
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 151 DTEAVLTILknDSLIKLMFVTSPGNPTGAKIKTSLIE---KVLQNWDnGLVVVDEAYVDFCGGSTapLVTKYP--NLVTL 225
Cdd:PRK06225 146 TPELVKENM--DENTRLIYLIDPLNPLGSSYTEEEIKefaEIARDND-AFLLHDCTYRDFAREHT--LAAEYApeHTVTS 220
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 226 QTLSKSFGLAGIRLGMTYATAELARILNAMK-APYNISSLASEYALKAvqdsnLK-KMEATSKIINE--EKMRLLKEltA 301
Cdd:PRK06225 221 YSFSKIFGMAGLRIGAVVATPDLIEVVKSIViNDLGTNVIAQEAAIAG-----LKvKDEWIDRIRRTtfKNQKLIKE--A 293
                        250       260
                 ....*....|....*....|....*
gi 285812538 302 LDYVDDQY--VGGLDANFLLIRING 324
Cdd:PRK06225 294 VDEIEGVFlpVYPSHGNMMVIDISE 318
PRK09276 PRK09276
LL-diaminopimelate aminotransferase; Provisional
52-302 6.35e-11

LL-diaminopimelate aminotransferase; Provisional


Pssm-ID: 181749  Cd Length: 385  Bit Score: 63.39  E-value: 6.35e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  52 HRYPDPH-QLEFKTAMTKYRNKTSSYANDP--EVKPLtadnlclgVGSDESIdAIIRACCV-PGkEKILVLPPTYSMYSV 127
Cdd:PRK09276  63 HQYPSYEgMLEFRKAVADWYKRRFGVELDPetEVISL--------IGSKEGI-AHIPLAFVnPG-DVVLVPDPGYPVYKI 132
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 128 CANINDIEVVQCPLTVSDGsFQMDTEAVLT-ILKNdslIKLMFVTSPGNPTGAKIKTSLIEKVLQnW--DNGLVVV-DEA 203
Cdd:PRK09276 133 GTIFAGGEPYFMPLKEENG-FLPDLDAIPEdVAKK---AKLMFINYPNNPTGAVADLEFFEEVVD-FakKYDIIVChDAA 207
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 204 YVDFC-GGSTAPLVTKYPNL----VTLQTLSKSFGLAGIRLGMTYATAELARILNAMKApyNISS-------LASEYALK 271
Cdd:PRK09276 208 YSEIAyDGYKPPSFLEVPGAkdvgIEFHSLSKTYNMTGWRIGFAVGNADLIAGLGKVKS--NVDSgvfqaiqEAGIAALN 285
                        250       260       270
                 ....*....|....*....|....*....|.
gi 285812538 272 AVQDSnlkkMEATSKIINEEKMRLLKELTAL 302
Cdd:PRK09276 286 GPQEV----VEELRKIYQERRDILVEGLRKL 312
PRK07681 PRK07681
LL-diaminopimelate aminotransferase;
60-257 6.56e-11

LL-diaminopimelate aminotransferase;


Pssm-ID: 181081  Cd Length: 399  Bit Score: 63.29  E-value: 6.56e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  60 LEFKTAMTKYRNKTSSYANDPEVKPLtadnlcLGVGSDESIDAIIRACCVPGkEKILVLPPTYSMYSVCANINDIEVVQC 139
Cdd:PRK07681  72 QEFHEAVTEYYNNTHNVILNADKEVL------LLMGSQDGLVHLPMVYANPG-DIILVPDPGYTAYETGIQMAGATSYYM 144
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 140 PLTvSDGSFQMDTEAVLTILKNDSliKLMFVTSPGNPTGAKIKTSLIEKVLQ--NWDNGLVVVDEAYVDFCGGSTAPL-V 216
Cdd:PRK07681 145 PLK-KENDFLPDLELIPEEIADKA--KMMILNFPGNPVPAMAHEDFFKEVIAfaKKHNIIVVHDFAYAEFYFDGNKPIsF 221
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 285812538 217 TKYPNL----VTLQTLSKSFGLAGIRLGMTYATAELARILNAMKA 257
Cdd:PRK07681 222 LSVPGAkevgVEINSLSKSYSLAGSRIGYMIGNEEIVRALTQFKS 266
tyr_nico_aTase TIGR01265
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ...
76-240 2.56e-10

tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.


Pssm-ID: 188123  Cd Length: 403  Bit Score: 61.59  E-value: 2.56e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   76 YANDPEVKpLTADNLCLGVGSDESIDAIIRACCVPGkEKILVLPPTYSMYSVCANINDIEVVQCPLtVSDGSFQMDTEAV 155
Cdd:TIGR01265  86 LSSDLPGK-LTADDVVLTSGCSQAIEICIEALANPG-ANILVPRPGFPLYDTRAAFSGLEVRLYDL-LPEKDWEIDLDGL 162
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  156 LTILknDSLIKLMFVTSPGNPTGAKIKTSLIEKVLQNWDN-GLVVV-DEAYVDFC-GGST----APLVTKYPnLVTLQTL 228
Cdd:TIGR01265 163 ESLA--DEKTVAIVVINPSNPCGSVFSRDHLQKIAEVAEKlGIPIIaDEIYGHMVfGDAPfipmASFASIVP-VLSLGGI 239
                         170
                  ....*....|..
gi 285812538  229 SKSFGLAGIRLG 240
Cdd:TIGR01265 240 SKRWVVPGWRLG 251
PRK08361 PRK08361
aspartate aminotransferase; Provisional
52-368 2.59e-10

aspartate aminotransferase; Provisional


Pssm-ID: 236248 [Multi-domain]  Cd Length: 391  Bit Score: 61.43  E-value: 2.59e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  52 HRYPDPHQLEFKTAMTKYRNKtsSYANDPEVkpltaDNLCLGVGSDESIDAIIRACCVPGKEkILVLPPTYSMYSVCANI 131
Cdd:PRK08361  65 HYTPNAGIPELREAIAEYYKK--FYGVDVDV-----DNVIVTAGAYEATYLAFESLLEEGDE-VIIPDPAFVCYVEDAKI 136
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 132 NDIEVVQCPLTvSDGSFQMDTEAVL-TILKNDSLIKLMFvtsPGNPTGAKIKTSL---IEKVLQNWdNGLVVVDEAYVDF 207
Cdd:PRK08361 137 AEAKPIRIPLR-EENEFQPDPDELLeLITKRTRMIVINY---PNNPTGATLDKEVakaIADIAEDY-NIYILSDEPYEHF 211
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 208 C--GGSTAPLVTKYP-NLVTLQTLSKSFGLAGIRLGMTYATAELARILNAMKApY---NISSLASEYALKAVQD-SNLKK 280
Cdd:PRK08361 212 LyeGAKHYPMIKYAPdNTILANSFSKTFAMTGWRLGFVIAPEQVIKDMIKLHA-YiigNVASFVQIAGIEALRSkESWKA 290
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 281 MEATSKIINEEKMRLLKELTALDYVDDQYVGGldANFLLIRINGGDnVLAKKLYYQLATQSGVVVrFRGNELG--CSGCL 358
Cdd:PRK08361 291 VEEMRKEYNERRKLVLKRLKEMPHIKVFEPKG--AFYVFANIDETG-MSSEDFAEWLLEKARVVV-IPGTAFGkaGEGYI 366
                        330
                 ....*....|
gi 285812538 359 RITVGTHEEN 368
Cdd:PRK08361 367 RISYATSKEK 376
tyr_amTase_E TIGR01264
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ...
70-240 2.93e-10

tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]


Pssm-ID: 273529 [Multi-domain]  Cd Length: 401  Bit Score: 61.34  E-value: 2.93e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538   70 RNKTSSYANDPEvKPLTADNLCLGVGSDESIDAIIRACCVPGkEKILVLPPTYSMYSVCANINDIEVVQCPLtVSDGSFQ 149
Cdd:TIGR01264  79 REAIASYYHNPD-GPIEADDVVLCSGCSHAIEMCIAALANAG-QNILVPRPGFPLYETLAESMGIEVKLYNL-LPDKSWE 155
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  150 MDTEAVLTILknDSLIKLMFVTSPGNPTGAKIKTSLIEKVLQNWDNGLVVV--DEAYVDFC-GGST----APLVTKYPnL 222
Cdd:TIGR01264 156 IDLKQLESLI--DEKTAALIVNNPSNPCGSVFSRQHLEEILAVAERQCLPIiaDEIYGDMVfSGATfeplASLSSTVP-I 232
                         170
                  ....*....|....*...
gi 285812538  223 VTLQTLSKSFGLAGIRLG 240
Cdd:TIGR01264 233 LSCGGLAKRWLVPGWRLG 250
PRK07682 PRK07682
aminotransferase;
60-275 1.16e-09

aminotransferase;


Pssm-ID: 181082 [Multi-domain]  Cd Length: 378  Bit Score: 59.36  E-value: 1.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  60 LEFKTAMTKYRNKTSSYANDPEvkpltaDNLCLGVGSDESIDAIIRACCVPGKEKILVLPPTYSMYSVCANINDIEVvqc 139
Cdd:PRK07682  60 LELRQEIAKYLKKRFAVSYDPN------DEIIVTVGASQALDVAMRAIINPGDEVLIVEPSFVSYAPLVTLAGGVPV--- 130
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 140 PL-TVSDGSFQM---DTEAVLTilkndSLIKLMFVTSPGNPTGAKIKTSLIEKVLQ--NWDNGLVVVDEAYVDFCGGSTA 213
Cdd:PRK07682 131 PVaTTLENEFKVqpaQIEAAIT-----AKTKAILLCSPNNPTGAVLNKSELEEIAVivEKHDLIVLSDEIYAELTYDEAY 205
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 285812538 214 PLVTKYPNL----VTLQTLSKSFGLAGIRLGMTYATAELARIL------NAMKAPyNISSLASEYALKAVQD 275
Cdd:PRK07682 206 TSFASIKGMrertILISGFSKGFAMTGWRLGFIAAPVYFSEAMlkihqySMMCAP-TMAQFAALEALRAGND 276
PRK07309 PRK07309
pyridoxal phosphate-dependent aminotransferase;
94-275 4.85e-09

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235985  Cd Length: 391  Bit Score: 57.43  E-value: 4.85e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  94 VGSDESIDAIIRACCVPGkEKILVLPPTYSMYSVCANINDIEVVQcpltvsdgsfqMDTEA---VLT-------ILKNDS 163
Cdd:PRK07309  98 IGATEALSASLTAILEPG-DKVLLPAPAYPGYEPIVNLVGAEIVE-----------IDTTEndfVLTpemlekaILEQGD 165
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 164 LIKLMFVTSPGNPTGAKIKTSLIE---KVLQNWDNgLVVVDEAYVD--FCGGSTAPLVTKYPNLVTL-QTLSKSFGLAGI 237
Cdd:PRK07309 166 KLKAVILNYPANPTGVTYSREQIKalaDVLKKYDI-FVISDEVYSEltYTGEPHVSIAEYLPDQTILiNGLSKSHAMTGW 244
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 285812538 238 RLGMTYATAEL-ARILNA----MKAPYNISSLASEYALKAVQD 275
Cdd:PRK07309 245 RIGLIFAPAEFtAQLIKShqylVTAATTMAQFAAVEALTNGKD 287
PRK08175 PRK08175
aminotransferase; Validated
37-275 1.20e-08

aminotransferase; Validated


Pssm-ID: 181268 [Multi-domain]  Cd Length: 395  Bit Score: 56.26  E-value: 1.20e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  37 NAHGPTP-------VELS-KTNLHRYPDPHQL-EFKTAMTKYRNKTSSYANDPEVKPLTAdnlclgVGSDESIDAIIRAC 107
Cdd:PRK08175  38 NPDGPTPphiveklCEVAqRPDTHGYSTSRGIpRLRRAISRWYQDRYDVDIDPESEAIVT------IGSKEGLAHLMLAT 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 108 CVPGkEKILVLPPTYSMYSVCANINDIEVVQCPLtVSDGSFQMDTEAVLtilkNDSLI--KLMFVTSPGNPTGAKIKTSL 185
Cdd:PRK08175 112 LDHG-DTVLVPNPSYPIHIYGAVIAGAQVRSVPL-VEGVDFFNELERAI----RESYPkpKMMILGFPSNPTAQCVELEF 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 186 IEKV--LQNWDNGLVVVDEAYVDFC-GGSTAPLVTKYPN----LVTLQTLSKSFGLAGIRLGMTYATAELARILNAMKA- 257
Cdd:PRK08175 186 FEKVvaLAKRYDVLVVHDLAYADIVyDGWKAPSIMQVPGakdvAVEFFTLSKSYNMAGWRIGFMVGNPELVSALARIKSy 265
                        250       260
                 ....*....|....*....|....*
gi 285812538 258 -------PYNISSLAseyALKAVQD 275
Cdd:PRK08175 266 hdygtftPLQVAAIA---ALEGDQQ 287
PLN00143 PLN00143
tyrosine/nicotianamine aminotransferase; Provisional
85-240 1.34e-08

tyrosine/nicotianamine aminotransferase; Provisional


Pssm-ID: 165711 [Multi-domain]  Cd Length: 409  Bit Score: 56.17  E-value: 1.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  85 LTADNLCLGVGSDESIDAIIRACCVPGKeKILVLPPTYSMYSVCANINDIEVVQCPLTVSDGsFQMDTEAVLTILKNDSL 164
Cdd:PLN00143  95 LSPDDVYLTLGCKHAAEIIIKVLARPEA-NILLPRPGFPDVETYAIFHHLEIRHFDLLPEKG-WEVDLDAVEAIADENTI 172
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 165 IklMFVTSPGNPTGAKIKTSLIEKVLQNWDNG--LVVVDEAYVDFCGGSTaPLV------TKYPnLVTLQTLSKSFGLAG 236
Cdd:PLN00143 173 A--MVIINPGNPCGSVYSYEHLNKIAETARKLgiLVIADEVYGHIVFGSK-PFVpmglfaSIVP-VITLGSISKRWMIPG 248

                 ....
gi 285812538 237 IRLG 240
Cdd:PLN00143 249 WGLG 252
PRK07550 PRK07550
aminotransferase;
84-255 1.65e-08

aminotransferase;


Pssm-ID: 181026 [Multi-domain]  Cd Length: 386  Bit Score: 55.73  E-value: 1.65e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  84 PLTADNLCLGVGSDESIDAIIRACCVPGKEKILVLP------PTYSMYSVCAnindievVQCPLTVSDGsFQMDTEAVLT 157
Cdd:PRK07550  87 AISPEQVHITSGCNQAFWAAMVTLAGAGDEVILPLPwyfnhkMWLDMLGIRP-------VYLPCDEGPG-LLPDPAAAEA 158
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 158 ILKndSLIKLMFVTSPGNPTGAKIKTSLIEKVLQ-NWDNGL-VVVDEAYVDFCGGSTAP--LVTKyPN----LVTLQTLS 229
Cdd:PRK07550 159 LIT--PRTRAIALVTPNNPTGVVYPPELLHELYDlARRHGIaLILDETYRDFDSGGGAPhdLFAD-PDwddtLVHLYSFS 235
                        170       180
                 ....*....|....*....|....*..
gi 285812538 230 KSFGLAGIRLGMTYATAELAR-ILNAM 255
Cdd:PRK07550 236 KSYALTGHRVGAVVASPARIAeIEKFM 262
PRK05957 PRK05957
pyridoxal phosphate-dependent aminotransferase;
95-369 2.80e-08

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 235654  Cd Length: 389  Bit Score: 55.08  E-value: 2.80e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  95 GSDESIDAIIRACCVPGKEKILVLPpTYSMYSVCANINDIEVVQCPltvSDGSFQMD-----------TEAVLTIlknds 163
Cdd:PRK05957  97 GSNMAFMNAILAITDPGDEIILNTP-YYFNHEMAITMAGCQPILVP---TDDNYQLQpeaieqaitpkTRAIVTI----- 167
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 164 liklmfvtSPGNPTGAKIKTSLIEKVLQNWD-NGLV-VVDEAYVDFCGG-----STAPLVTKYPNLVTLQTLSKSFGLAG 236
Cdd:PRK05957 168 --------SPNNPTGVVYPEALLRAVNQICAeHGIYhISDEAYEYFTYDgvkhfSPGSIPGSGNHTISLYSLSKAYGFAS 239
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 237 IRLGMTYATAELARILNAMK-----APYNISSLASEYALKAVQD---SNLKKMEATSKIineekmrLLKELTAL-DYVDD 307
Cdd:PRK05957 240 WRIGYMVIPIHLLEAIKKIQdtiliCPPVVSQYAALGALQVGKSycqQHLPEIAQVRQI-------LLKSLGQLqDRCTL 312
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 285812538 308 QYVGGldANFLLIRINGG--DNVLAKKLY--YQLATQSGVVVrfrGNELGCSgcLRITVGTHEENT 369
Cdd:PRK05957 313 HPANG--AFYCFLKVNTDlnDFELVKQLIreYRVAVIPGTTF---GMKNGCY--LRIAYGALQKAT 371
PRK06836 PRK06836
pyridoxal phosphate-dependent aminotransferase;
44-240 4.83e-08

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180720  Cd Length: 394  Bit Score: 54.43  E-value: 4.83e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  44 VELSKTNLHRY-PDPHQLEFKTAMTKYRNKTSSyandpevKPLTADNLCLGVGSDESIDAIIRACCVPGKEkILVLPPTY 122
Cdd:PRK06836  59 AEEEDPGLHGYmPNAGYPEVREAIAESLNRRFG-------TPLTADHIVMTCGAAGALNVALKAILNPGDE-VIVFAPYF 130
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 123 SMYSVCANINDIEVVQCPLTVSDgsFQMDTEAVLTILknDSLIKLMFVTSPGNPTGA--------KIKTSLIEKVLQNWD 194
Cdd:PRK06836 131 VEYRFYVDNHGGKLVVVPTDTDT--FQPDLDALEAAI--TPKTKAVIINSPNNPTGVvyseetlkALAALLEEKSKEYGR 206
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 285812538 195 NGLVVVDEAYVDFC-GGSTAPLVTK-YPNLVTLQTLSKSFGLAGIRLG 240
Cdd:PRK06836 207 PIYLISDEPYREIVyDGAEVPYIFKyYDNSIVVYSFSKSLSLPGERIG 254
PRK08363 PRK08363
alanine aminotransferase; Validated
85-266 1.73e-06

alanine aminotransferase; Validated


Pssm-ID: 181402  Cd Length: 398  Bit Score: 49.42  E-value: 1.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  85 LTADNLCLGVGSDESIDAIIRACCVPGKEkILVLPPTYSMYSVCANINDIEVVQCpLTVSDGSFQMDTEAVLTilKNDSL 164
Cdd:PRK08363  91 ITPDDVRVTAAVTEALQLIFGALLDPGDE-ILIPGPSYPPYTGLVKFYGGVPVEY-RTIEEEGWQPDIDDIRK--KITEK 166
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 165 IKLMFVTSPGNPTGAKIKTSLIEKVLQ--NWDNGLVVVDEAY--VDFCGGSTAP-LVTKYPNLVTLQTLSKSFGLAGIRL 239
Cdd:PRK08363 167 TKAIAVINPNNPTGALYEKKTLKEILDiaGEHDLPVISDEIYdlMTYEGKHVSPgSLTKDVPVIVMNGLSKVYFATGWRL 246
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 285812538 240 GMTY-------------ATAELARILNAMKAPYNISSLAS 266
Cdd:PRK08363 247 GYIYfvdpegklaevreAIDKLARIRLCPNTPAQFAAIAG 286
PRK07324 PRK07324
transaminase; Validated
166-252 2.14e-06

transaminase; Validated


Pssm-ID: 235989  Cd Length: 373  Bit Score: 49.17  E-value: 2.14e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 166 KLMFVTSPGNPTGAKIKTSLIEKV--LQNWDNGLVVVDEAYVDFC-GGSTAPLVTKYPNLVTLQTLSKSFGLAGIRLGMT 242
Cdd:PRK07324 155 KLICINNANNPTGALMDRAYLEEIveIARSVDAYVLSDEVYRPLDeDGSTPSIADLYEKGISTNSMSKTYSLPGIRVGWI 234
                         90
                 ....*....|
gi 285812538 243 YATAELARIL 252
Cdd:PRK07324 235 AANEEVIDIL 244
PRK06107 PRK06107
aspartate transaminase;
87-275 5.32e-06

aspartate transaminase;


Pssm-ID: 180403  Cd Length: 402  Bit Score: 48.19  E-value: 5.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  87 ADN-LCLGVGSDESIDAIIRACCVPGKEkILVLPPTYSMYS--VCANINDIEVVQCPltvSDGSFQMDTEAVLTILKNDS 163
Cdd:PRK06107  92 ADNeITVGGGAKQAIFLALMATLEAGDE-VIIPAPYWVSYPdmVLANDGTPVIVACP---EEQGFKLTPEALEAAITPRT 167
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 164 liKLMFVTSPGNPTGAKIKTSLIE---KVLQNWDNGLVVVDEAY--VDFCGGSTAPLVTKYPNLV--TLQT--LSKSFGL 234
Cdd:PRK06107 168 --RWLILNAPSNPTGAVYSRAELRalaDVLLRHPHVLVLTDDIYdhIRFDDEPTPHLLAAAPELRdrVLVTngVSKTYAM 245
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 285812538 235 AGIRLGMTYATAELARILNAMKA-----PYNISSLASEYALKAVQD 275
Cdd:PRK06107 246 TGWRIGYAAGPADLIAAINKLQSqssscPSSISQAAAAAALNGDQS 291
PRK06108 PRK06108
pyridoxal phosphate-dependent aminotransferase;
83-275 6.21e-06

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180404  Cd Length: 382  Bit Score: 47.63  E-value: 6.21e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  83 KPLTADNLCLGVGSDESIDAIIRACCVPGKEkILVLPPTYSMYSVCANINDIEVVQCPLTVSDGSFQMDTEAVLTILKND 162
Cdd:PRK06108  80 VATPPERIAVTSSGVQALMLAAQALVGPGDE-VVAVTPLWPNLVAAPKILGARVVCVPLDFGGGGWTLDLDRLLAAITPR 158
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 163 SliKLMFVTSPGNPTGAKIKTSLIEKVLQN------WdnglVVVDEAY--VDFCGGSTAP----LVTKYPNLVTLQTLSK 230
Cdd:PRK06108 159 T--RALFINSPNNPTGWTASRDDLRAILAHcrrhglW----IVADEVYerLYYAPGGRAPsfldIAEPDDRIIFVNSFSK 232
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 285812538 231 SFGLAGIRLGMTYATAELARILNAMkAPYNISSLAS---EYALKAVQD 275
Cdd:PRK06108 233 NWAMTGWRLGWLVAPPALGQVLEKL-IEYNTSCVAQfvqRAAVAALDE 279
PLN02656 PLN02656
tyrosine transaminase
85-240 1.31e-05

tyrosine transaminase


Pssm-ID: 178262 [Multi-domain]  Cd Length: 409  Bit Score: 46.84  E-value: 1.31e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  85 LTADNLCLGVGSDESIDAIIRACCVPGKeKILVLPPTYSMYSVCANINDIEVVQCPLTVSDGsFQMDTEAVlTILKNDSL 164
Cdd:PLN02656  94 LSLDDVFITSGCTQAIDVALSMLARPGA-NILLPRPGFPIYELCAAFRHLEVRYVDLLPEKG-WEVDLDAV-EALADQNT 170
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 165 IKLMfVTSPGNPTGAKIKTSLIEKVLQNWD--NGLVVVDEAYVDFCGGSTaPLV------TKYPnLVTLQTLSKSFGLAG 236
Cdd:PLN02656 171 VALV-IINPGNPCGNVYSYQHLKKIAETAEklKILVIADEVYGHLAFGSN-PFVpmgvfgSIVP-VLTLGSLSKRWIVPG 247

                 ....
gi 285812538 237 IRLG 240
Cdd:PLN02656 248 WRLG 251
PRK07568 PRK07568
pyridoxal phosphate-dependent aminotransferase;
66-305 1.51e-05

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181036  Cd Length: 397  Bit Score: 46.77  E-value: 1.51e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  66 MTKYRNKTSSYANDPEVKpLTADNLCLGVGSDESIDAIIRACCVPGKEkILVLPPTYSMYSVCANINDIEVVQCPLTVSD 145
Cdd:PRK07568  68 IPELREAFAKYYKKWGID-VEPDEILITNGGSEAILFAMMAICDPGDE-ILVPEPFYANYNGFATSAGVKIVPVTTKIEE 145
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 146 GsFQM----DTEAVLTilkndSLIKLMFVTSPGNPTGA--------KIKTSLIEKVLqnwdngLVVVDEAYVDFC-GGST 212
Cdd:PRK07568 146 G-FHLpskeEIEKLIT-----PKTKAILISNPGNPTGVvytkeeleMLAEIAKKHDL------FLISDEVYREFVyDGLK 213
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 213 APLVTKYP----NLVTLQTLSKSFGLAGIRLGmTYATAELARILNAMK------APYNISSLASEYALKAVQdsnlkkmE 282
Cdd:PRK07568 214 YTSALSLEgledRVIIIDSVSKRYSACGARIG-CLISKNKELIAAAMKlcqarlSPPTLEQIGAAALLDTPE-------S 285
                        250       260
                 ....*....|....*....|....*.
gi 285812538 283 ATSKIINEEKMR---LLKELTALDYV 305
Cdd:PRK07568 286 YFDEVREEYKKRrdiLYEELNKIPGV 311
PLN00175 PLN00175
aminotransferase family protein; Provisional
61-250 1.68e-05

aminotransferase family protein; Provisional


Pssm-ID: 215089 [Multi-domain]  Cd Length: 413  Bit Score: 46.40  E-value: 1.68e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  61 EFKTAMTKYRNKTSSYANDPEvKPLTADNLClgvgsDESIDAIIRACCVPGKEkILVLPPTYSMYSVC-----ANINDIE 135
Cdd:PLN00175  95 ELNSAIAERFKKDTGLVVDPE-KEVTVTSGC-----TEAIAATILGLINPGDE-VILFAPFYDSYEATlsmagAKIKTVT 167
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 136 V----VQCPLTVSDGSFQMDTEAVLtilkndsliklmfVTSPGNPTGAKIKTSLIEKV--LQNWDNGLVVVDEAY--VDF 207
Cdd:PLN00175 168 LrppdFAVPEDELKAAFTSKTRAIL-------------INTPHNPTGKMFTREELELIasLCKENDVLAFTDEVYdkLAF 234
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 285812538 208 CGG--STAPLVTKYPNLVTLQTLSKSFGLAGIRLGMTYATAELAR 250
Cdd:PLN00175 235 EGDhiSMASLPGMYERTVTMNSLGKTFSLTGWKIGWAIAPPHLTW 279
PRK06290 PRK06290
LL-diaminopimelate aminotransferase;
54-240 5.10e-05

LL-diaminopimelate aminotransferase;


Pssm-ID: 235772  Cd Length: 410  Bit Score: 45.03  E-value: 5.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  54 YPDPHQLEFKTAMTKYRNKTSSyandpeVKPLTADNLCL-GVGSdESIDAIIRACCV-PGkEKILVLPPTYSMYSVCANI 131
Cdd:PRK06290  78 YADNGIQEFKEAAARYMEKVFG------VKDIDPVTEVIhSIGS-KPALAMLPSCFInPG-DVTLMTVPGYPVTGTHTKY 149
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 132 NDIEVVQCPLTvSDGSFQMDTEAVLTILKNDSliKLMFVTSPGNPTGAKIKTSLIEKVLQ-NWDNGLVVV-DEAYvdfcg 209
Cdd:PRK06290 150 YGGEVYNLPLL-EENNFLPDLDSIPKDIKEKA--KLLYLNYPNNPTGAVATKEFYEEVVDfAKENNIIVVqDAAY----- 221
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 285812538 210 gstAPLVTKYPNL------------VTLQTLSKSFGLAGIRLG 240
Cdd:PRK06290 222 ---AALTFDGKPLsflsvpgakevgVEIHSLSKAYNMTGWRLA 261
PRK07683 PRK07683
aminotransferase A; Validated
94-273 8.91e-05

aminotransferase A; Validated


Pssm-ID: 236075  Cd Length: 387  Bit Score: 44.33  E-value: 8.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  94 VGSDESIDAIIRACCVPGKEKILvlP-PTYSMYSVCANINDIEVVQcpLTVSDGSFQMDTEAVLTILKNDSliKLMFVTS 172
Cdd:PRK07683  96 IGASEAIDIAFRTILEPGTEVIL--PaPIYPGYEPIIRLCGAKPVF--IDTRSTGFRLTAEALENAITEKT--RCVVLPY 169
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 173 PGNPTGAkiktSLIEKVLQNWDNGL------VVVDEAYVDFCGGSTAPLVTKYPNL----VTLQTLSKSFGLAGIRLGMT 242
Cdd:PRK07683 170 PSNPTGV----TLSKEELQDIADVLkdknifVLSDEIYSELVYEQPHTSIAHFPEMrektIVINGLSKSHSMTGWRIGFL 245
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 285812538 243 YATAELAR-ILNAMKapYNI---SSLASEYALKAV 273
Cdd:PRK07683 246 FAPSYLAKhILKVHQ--YNVtcaSSISQYAALEAL 278
PRK07366 PRK07366
LL-diaminopimelate aminotransferase;
166-257 1.59e-04

LL-diaminopimelate aminotransferase;


Pssm-ID: 180947  Cd Length: 388  Bit Score: 43.51  E-value: 1.59e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 166 KLMFVTSPGNPTGAKIKTSLIEKVLQ-NWDNGLVVV-DEAYVD--FCGGSTAP--LVTKYPNLVTLQ--TLSKSFGLAGI 237
Cdd:PRK07366 167 RLMVLSYPHNPTTAIAPLSFFQEAVAfCQQHDLVLVhDFPYVDlvFDGEVEPPsiLQADPEKSVSIEffTLSKSYNMGGF 246
                         90       100
                 ....*....|....*....|
gi 285812538 238 RLGMTYATAELARILNAMKA 257
Cdd:PRK07366 247 RIGFAIGNAQLIQALRQVKA 266
PRK08960 PRK08960
pyridoxal phosphate-dependent aminotransferase;
170-302 2.40e-04

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 181595  Cd Length: 387  Bit Score: 42.73  E-value: 2.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 170 VTSPGNPTGAKIK----TSLIEKVLQNwdNGLVVVDEAYVDFCGGSTAPLVTKYPN-LVTLQTLSKSFGLAGIRLGMTYA 244
Cdd:PRK08960 171 VASPANPTGTLLSrdelAALSQALRAR--GGHLVVDEIYHGLTYGVDAASVLEVDDdAFVLNSFSKYFGMTGWRLGWLVA 248
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 245 TAELARILNAMKAPYNIS--SLASEYALKAVQDSNLKKMEATSKIINEEKMRLLKELTAL 302
Cdd:PRK08960 249 PPAAVPELEKLAQNLYISasTPAQHAALACFEPETLAILEARRAEFARRRDFLLPALREL 308
PTZ00433 PTZ00433
tyrosine aminotransferase; Provisional
61-362 6.60e-04

tyrosine aminotransferase; Provisional


Pssm-ID: 185613  Cd Length: 412  Bit Score: 41.70  E-value: 6.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  61 EFKTAMTKYRNKtsSYANDPEVKP-LTADNLCLGVGSDESIDAIIRACCVPGkEKILVLPPTYSMY-SVCANINdievVQ 138
Cdd:PTZ00433  79 EAREAVATYWRN--SFVHKESLKStIKKDNVVLCSGVSHAILMALTALCDEG-DNILVPAPGFPHYeTVCKAYG----IE 151
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 139 CPLTVSDGSfqMDTEAVLTILKN--DSLIKLMFVTSPGNPTGAKIKTSLIEKVLQNWDNGLV--VVDEAYVD--FCGG-- 210
Cdd:PTZ00433 152 MRFYNCRPE--KDWEADLDEIRRlvDDRTKALIMTNPSNPCGSNFSRKHVEDIIRLCEELRLplISDEIYAGmvFNGAtf 229
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 211 -STAPLVTKYPNLVtLQTLSKSFGLAGIRLG-------MTYAtaelARILNAMK-------APYNISSLASEYALKAVQD 275
Cdd:PTZ00433 230 tSVADFDTTVPRVI-LGGTAKNLVVPGWRLGwlllvdpHGNG----GDFLDGMKrlgmlvcGPCSVVQAALGEALLNTPQ 304
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 276 SNLK----KMEATSKIINeekmRLLKELTALDYVDDQyvgglDANFLLIRINGG---DNVLAKKLYYQLATQSGVVVrFR 348
Cdd:PTZ00433 305 EHLEqivaKLEEGAMVLY----NHIGECIGLSPTMPR-----GSMFLMSRLDLEkfrDIKSDVEFYEKLLEEENVQV-LP 374
                        330
                 ....*....|....
gi 285812538 349 GNELGCSGCLRITV 362
Cdd:PTZ00433 375 GEIFHMPGFTRLTI 388
PRK06348 PRK06348
pyridoxal phosphate-dependent aminotransferase;
142-271 7.92e-04

pyridoxal phosphate-dependent aminotransferase;


Pssm-ID: 180537  Cd Length: 384  Bit Score: 41.24  E-value: 7.92e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 142 TVSDGSFQMDTEavltILKN--DSLIKLMFVTSPGNPTGAKIKTSL---IEKVLQNWDNgLVVVDEAYVDFCGGST-APL 215
Cdd:PRK06348 142 TYEEDGFQINVK----KLEAliTSKTKAIILNSPNNPTGAVFSKETleeIAKIAIEYDL-FIISDEVYDGFSFYEDfVPM 216
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 285812538 216 VT--KYP-NLVTLQTLSKSFGLAGIRLGMTYATA---ELARILN---AMKAPyNISSLASEYALK 271
Cdd:PRK06348 217 ATlaGMPeRTITFGSFSKDFAMTGWRIGYVIAPDyiiETAKIINegiCFSAP-TISQRAAIYALK 280
PLN02376 PLN02376
1-aminocyclopropane-1-carboxylate synthase
51-244 9.01e-04

1-aminocyclopropane-1-carboxylate synthase


Pssm-ID: 178004 [Multi-domain]  Cd Length: 496  Bit Score: 41.22  E-value: 9.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  51 LHRYPDPHQLEFKTAMTKYRNKTSSYANDPEVKPLTAD--NLCLGVGSDESIDAIIRACCVPGkEKILVLPPTYSMYSVC 128
Cdd:PLN02376  81 IHQFSDIANFQDYHGLKKFRQAIAHFMGKARGGKVTFDpeRVVMSGGATGANETIMFCLADPG-DVFLIPSPYYAAFDRD 159
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 129 ANI-NDIEVVQCPLTVSDgSFQMDTEAVLTILK----NDSLIKLMFVTSPGNPTGAKIK----TSLIEKVLQNwdNGLVV 199
Cdd:PLN02376 160 LRWrTGVEIIPVPCSSSD-NFKLTVDAADWAYKkaqeSNKKVKGLILTNPSNPLGTMLDkdtlTNLVRFVTRK--NIHLV 236
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 285812538 200 VDEAYVD--FCGG---STAPLVTKYP------NLV-TLQTLSKSFGLAGIRLGMTYA 244
Cdd:PLN02376 237 VDEIYAAtvFAGGdfvSVAEVVNDVDisevnvDLIhIVYSLSKDMGLPGFRVGIVYS 293
PRK08636 PRK08636
LL-diaminopimelate aminotransferase;
91-257 2.90e-03

LL-diaminopimelate aminotransferase;


Pssm-ID: 236316  Cd Length: 403  Bit Score: 39.30  E-value: 2.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538  91 CLGVGSDESIDAIIRACCVPGKEKIlVLPPTYSMYSVCANINDIEVVQCPLTVSDgSFQMDTEAVLTILK---NDSL--I 165
Cdd:PRK08636  99 VATMGSKEGYVHLVQAITNPGDVAI-VPDPAYPIHSQAFILAGGNVHKMPLEYNE-DFELDEDQFFENLEkalRESSpkP 176
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 166 KLMFVTSPGNPTGAKIKTSLIEKV--LQNWDNGLVVVDEAYVDFC-GGSTAPLVTKYPNL----VTLQTLSKSFGLAGIR 238
Cdd:PRK08636 177 KYVVVNFPHNPTTATVEKSFYERLvaLAKKERFYIISDIAYADITfDGYKTPSILEVEGAkdvaVESYTLSKSYNMAGWR 256
                        170
                 ....*....|....*....
gi 285812538 239 LGMTYATAELARILNAMKA 257
Cdd:PRK08636 257 VGFVVGNKKLVGALKKIKS 275
PRK05764 PRK05764
aspartate aminotransferase; Provisional
106-281 3.22e-03

aspartate aminotransferase; Provisional


Pssm-ID: 235596  Cd Length: 393  Bit Score: 39.34  E-value: 3.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 106 ACCVPGKEkILVLPPTYSMYSVCANINDIEVVQCPLTVSDGsFQMDTEAVLTILKNDSliKLMFVTSPGNPTGAKIKTSL 185
Cdd:PRK05764 110 ALLDPGDE-VIIPAPYWVSYPEMVKLAGGVPVFVPTGEENG-FKLTVEQLEAAITPKT--KALILNSPSNPTGAVYSPEE 185
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 285812538 186 IEKvLQNW--DNGLVVV-DE-----AYVDFCGGSTAPLVTK-YPNLVTLQTLSKSFGLAGIRLGmtYATAElARILNAMK 256
Cdd:PRK05764 186 LEA-IADVavEHDIWVLsDEiyeklVYDGAEFTSIASLSPElRDRTITVNGFSKAYAMTGWRLG--YAAGP-KELIKAMS 261
                        170       180       190
                 ....*....|....*....|....*....|...
gi 285812538 257 --------APYNISSLASEYALKAVQDSnLKKM 281
Cdd:PRK05764 262 klqshstsNPTSIAQYAAVAALNGPQDE-VEEM 293
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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