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Conserved domains on  [gi|285812660|tpg|DAA08559|]
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TPA: Gat4p [Saccharomyces cerevisiae S288C]

Protein Classification

GATA-type transcription factor( domain architecture ID 10078896)

GATA-type transcription factor binds to the DNA consensus sequence [AT]GATA[AG] and may function as a transcription factor/regulator

CATH:  3.30.50.10
Gene Ontology:  GO:0003700|GO:0006357|GO:0008270|GO:0043565
PubMed:  31574210
SCOP:  4003617

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 52-108 4.90e-14

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


:

Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 61.62  E-value: 4.90e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 285812660  52 TCGQCGEIKTSLqWREGPNGAACLCNACGLFFRKliLRFGRAAAKRYMEQIKGTGTK 108
Cdd:cd00202    1 ACSNCGTTTTPL-WRRGPSGGSTLCNACGLYWKK--HGVMRPLSKRKKDQIKRRNRK 54
 
Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 52-108 4.90e-14

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 61.62  E-value: 4.90e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 285812660  52 TCGQCGEIKTSLqWREGPNGAACLCNACGLFFRKliLRFGRAAAKRYMEQIKGTGTK 108
Cdd:cd00202    1 ACSNCGTTTTPL-WRRGPSGGSTLCNACGLYWKK--HGVMRPLSKRKKDQIKRRNRK 54
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 53-85 1.06e-11

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 55.02  E-value: 1.06e-11
                          10        20        30
                  ....*....|....*....|....*....|...
gi 285812660   53 CGQCGEIKTSlQWREGPNGAACLCNACGLFFRK 85
Cdd:pfam00320   1 CSNCGTTKTP-LWRRGPNGNRTLCNACGLYYKK 32
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
48-103 1.30e-11

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 55.12  E-value: 1.30e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 285812660    48 GITRTCGQCGeIKTSLQWREGPNGAACLCNACGLFFRKlilRFGRAAAKRYMEQIK 103
Cdd:smart00401   1 GSGRSCSNCG-TTETPLWRRGPSGNKTLCNACGLYYKK---HGGLKRPLSLKKDGI 52
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
50-121 1.81e-04

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 39.47  E-value: 1.81e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 285812660  50 TRTCGQCGEIKTSLQWREGPNGAACLCNACGLFFRKLILRFGRAAAKRYMEQIKGTGTKRRIPKELTGTVRF 121
Cdd:COG5641  232 TESIGNSSASKLTKSWEERPQGRQLLSDAGSLSPRSNNPKSPLLEGLMGSTSLQPVSTPKLVLPSDKKRSTL 303
 
Name Accession Description Interval E-value
ZnF_GATA cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] ...
 52-108 4.90e-14

Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C


Pssm-ID: 238123 [Multi-domain]  Cd Length: 54  Bit Score: 61.62  E-value: 4.90e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 285812660  52 TCGQCGEIKTSLqWREGPNGAACLCNACGLFFRKliLRFGRAAAKRYMEQIKGTGTK 108
Cdd:cd00202    1 ACSNCGTTTTPL-WRRGPSGGSTLCNACGLYWKK--HGVMRPLSKRKKDQIKRRNRK 54
GATA pfam00320
GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This ...
 53-85 1.06e-11

GATA zinc finger; This domain uses four cysteine residues to coordinate a zinc ion. This domain binds to DNA. Two GATA zinc fingers are found in the GATA transcription factors. However there are several proteins which only contain a single copy of the domain.


Pssm-ID: 425605 [Multi-domain]  Cd Length: 36  Bit Score: 55.02  E-value: 1.06e-11
                          10        20        30
                  ....*....|....*....|....*....|...
gi 285812660   53 CGQCGEIKTSlQWREGPNGAACLCNACGLFFRK 85
Cdd:pfam00320   1 CSNCGTTKTP-LWRRGPNGNRTLCNACGLYYKK 32
ZnF_GATA smart00401
zinc finger binding to DNA consensus sequence [AT]GATA[AG];
48-103 1.30e-11

zinc finger binding to DNA consensus sequence [AT]GATA[AG];


Pssm-ID: 214648 [Multi-domain]  Cd Length: 52  Bit Score: 55.12  E-value: 1.30e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 285812660    48 GITRTCGQCGeIKTSLQWREGPNGAACLCNACGLFFRKlilRFGRAAAKRYMEQIK 103
Cdd:smart00401   1 GSGRSCSNCG-TTETPLWRRGPSGNKTLCNACGLYYKK---HGGLKRPLSLKKDGI 52
GAT1 COG5641
GATA Zn-finger-containing transcription factor [Transcription];
50-121 1.81e-04

GATA Zn-finger-containing transcription factor [Transcription];


Pssm-ID: 227928 [Multi-domain]  Cd Length: 498  Bit Score: 39.47  E-value: 1.81e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 285812660  50 TRTCGQCGEIKTSLQWREGPNGAACLCNACGLFFRKLILRFGRAAAKRYMEQIKGTGTKRRIPKELTGTVRF 121
Cdd:COG5641  232 TESIGNSSASKLTKSWEERPQGRQLLSDAGSLSPRSNNPKSPLLEGLMGSTSLQPVSTPKLVLPSDKKRSTL 303
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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