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Conserved domains on  [gi|363805508|sp|E3KIY6|]
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RecName: Full=U1 small nuclear ribonucleoprotein C-2; Short=U1 snRNP C-2; Short=U1-C-2; Short=U1C-2

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 10533256)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0003676|GO:0008270|GO:0003700
PubMed:  11179890|11361095|10940247|22803940|12665246
SCOP:  4003583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-U1 pfam06220
U1 zinc finger; This family consists of several U1 small nuclear ribonucleoprotein C (U1-C) ...
 1-38 3.89e-18

U1 zinc finger; This family consists of several U1 small nuclear ribonucleoprotein C (U1-C) proteins. The U1 small nuclear ribonucleoprotein (U1 snRNP) binds to the pre-mRNA 5' splice site (ss) at early stages of spliceosome assembly. Recruitment of U1 to a class of weak 5' ss is promoted by binding of the protein TIA-1 to uridine-rich sequences immediately downstream from the 5' ss. Binding of TIA-1 in the vicinity of a 5' ss helps to stabilize U1 snRNP recruitment, at least in part, via a direct interaction with U1-C, thus providing one molecular mechanism for the function of this splicing regulator. This domain is probably a zinc-binding. It is found in multiple copies in some members of the family.


:

Pssm-ID: 368798  Cd Length: 38  Bit Score: 73.62  E-value: 3.89e-18
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 363805508    1 MGKYYCDYCDVFLVSESPSVRKAHNSGRNHLTNVRDYY 38
Cdd:pfam06220   1 MPKYYCDYCDCYLTHDSPSVRKSHNGGRKHKDNVKDYY 38
PABP-1234 super family cl31127
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 70-179 1.21e-05

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


The actual alignment was detected with superfamily member TIGR01628:

Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 44.80  E-value: 1.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508   70 PGGNP-PGSQPGPPNAGMSGPMRPPfSNSTAGPNMPPLPPAMlalmngqngmsSPGSGPPPMRFAGPP------------ 136
Cdd:TIGR01628 386 PMGSPmGGAMGQPPYYGQGPQQQFN-GQPLGWPRMSMMPTPM-----------GPGGPLRPNGLAPMNavrapsrnaqna 453

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 363805508  137 IPNNMPPGMMQPPHVNGYSSGPLPPQPQPASGGQGAPPLTARM 179
Cdd:TIGR01628 454 AQKPPMQPVMYPPNYQSLPLSQDLPQPQSTASQGGQNKKLAQV 496
 
Name Accession Description Interval E-value
zf-U1 pfam06220
U1 zinc finger; This family consists of several U1 small nuclear ribonucleoprotein C (U1-C) ...
 1-38 3.89e-18

U1 zinc finger; This family consists of several U1 small nuclear ribonucleoprotein C (U1-C) proteins. The U1 small nuclear ribonucleoprotein (U1 snRNP) binds to the pre-mRNA 5' splice site (ss) at early stages of spliceosome assembly. Recruitment of U1 to a class of weak 5' ss is promoted by binding of the protein TIA-1 to uridine-rich sequences immediately downstream from the 5' ss. Binding of TIA-1 in the vicinity of a 5' ss helps to stabilize U1 snRNP recruitment, at least in part, via a direct interaction with U1-C, thus providing one molecular mechanism for the function of this splicing regulator. This domain is probably a zinc-binding. It is found in multiple copies in some members of the family.


Pssm-ID: 368798  Cd Length: 38  Bit Score: 73.62  E-value: 3.89e-18
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 363805508    1 MGKYYCDYCDVFLVSESPSVRKAHNSGRNHLTNVRDYY 38
Cdd:pfam06220   1 MPKYYCDYCDCYLTHDSPSVRKSHNGGRKHKDNVKDYY 38
COG5136 COG5136
U1 snRNP-specific protein C [RNA processing and modification];
1-112 5.18e-12

U1 snRNP-specific protein C [RNA processing and modification];


Pssm-ID: 227465 [Multi-domain]  Cd Length: 188  Bit Score: 61.64  E-value: 5.18e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508   1 MGKYYCDYCDVFLVSESPSVRKAHNSGRNHLTNVRDYYSSLGHD---KAQSYIDEITR---MFETGGGNSTSNRGPGGNP 74
Cdd:COG5136    1 MPRYFCEYCNKMLTHDRLSVRKMHCGGAKHGLMRKDYYMEMAEDiaaEMASILRDIKTageKVECEGNKSTSYPPFPAFP 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 363805508  75 PGSQ-----PGPPNAGMSGPMRPPFSNSTAGPNMPPLPPAMLA 112
Cdd:COG5136   81 PGDFylnlaLPEPPKGFVLANGFDFRDKKNAPENITEAIERYA 123
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 1-37 2.57e-07

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 45.32  E-value: 2.57e-07
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 363805508     1 MGKYYCDYCDVFLvSESPSVRkAHNSGRNHLTNVRDY 37
Cdd:smart00451   1 TGGFYCKLCNVTF-TDEISVE-AHLKGKKHKKNVKKR 35
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 70-179 1.21e-05

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 44.80  E-value: 1.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508   70 PGGNP-PGSQPGPPNAGMSGPMRPPfSNSTAGPNMPPLPPAMlalmngqngmsSPGSGPPPMRFAGPP------------ 136
Cdd:TIGR01628 386 PMGSPmGGAMGQPPYYGQGPQQQFN-GQPLGWPRMSMMPTPM-----------GPGGPLRPNGLAPMNavrapsrnaqna 453

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 363805508  137 IPNNMPPGMMQPPHVNGYSSGPLPPQPQPASGGQGAPPLTARM 179
Cdd:TIGR01628 454 AQKPPMQPVMYPPNYQSLPLSQDLPQPQSTASQGGQNKKLAQV 496
PHA03247 PHA03247
large tegument protein UL36; Provisional
 62-173 1.76e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 1.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508   62 GNSTSNRGPGGNPPGSQPGPPNAGMSGPMRPPFSNSTAGPNMPPLPPAMLalmngqngmSSPGSGPPPMrfagPPIPNNM 141
Cdd:PHA03247 2859 GGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERP---------PQPQAPPPPQ----PQPQPPP 2925

                          90       100       110
                  ....*....|....*....|....*....|..
gi 363805508  142 PPGMMQPPHVNGYSSGPLPPQPQPASGGQGAP 173
Cdd:PHA03247 2926 PPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSG 2957
 
Name Accession Description Interval E-value
zf-U1 pfam06220
U1 zinc finger; This family consists of several U1 small nuclear ribonucleoprotein C (U1-C) ...
 1-38 3.89e-18

U1 zinc finger; This family consists of several U1 small nuclear ribonucleoprotein C (U1-C) proteins. The U1 small nuclear ribonucleoprotein (U1 snRNP) binds to the pre-mRNA 5' splice site (ss) at early stages of spliceosome assembly. Recruitment of U1 to a class of weak 5' ss is promoted by binding of the protein TIA-1 to uridine-rich sequences immediately downstream from the 5' ss. Binding of TIA-1 in the vicinity of a 5' ss helps to stabilize U1 snRNP recruitment, at least in part, via a direct interaction with U1-C, thus providing one molecular mechanism for the function of this splicing regulator. This domain is probably a zinc-binding. It is found in multiple copies in some members of the family.


Pssm-ID: 368798  Cd Length: 38  Bit Score: 73.62  E-value: 3.89e-18
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 363805508    1 MGKYYCDYCDVFLVSESPSVRKAHNSGRNHLTNVRDYY 38
Cdd:pfam06220   1 MPKYYCDYCDCYLTHDSPSVRKSHNGGRKHKDNVKDYY 38
COG5136 COG5136
U1 snRNP-specific protein C [RNA processing and modification];
1-112 5.18e-12

U1 snRNP-specific protein C [RNA processing and modification];


Pssm-ID: 227465 [Multi-domain]  Cd Length: 188  Bit Score: 61.64  E-value: 5.18e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508   1 MGKYYCDYCDVFLVSESPSVRKAHNSGRNHLTNVRDYYSSLGHD---KAQSYIDEITR---MFETGGGNSTSNRGPGGNP 74
Cdd:COG5136    1 MPRYFCEYCNKMLTHDRLSVRKMHCGGAKHGLMRKDYYMEMAEDiaaEMASILRDIKTageKVECEGNKSTSYPPFPAFP 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 363805508  75 PGSQ-----PGPPNAGMSGPMRPPFSNSTAGPNMPPLPPAMLA 112
Cdd:COG5136   81 PGDFylnlaLPEPPKGFVLANGFDFRDKKNAPENITEAIERYA 123
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 1-37 2.57e-07

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 45.32  E-value: 2.57e-07
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 363805508     1 MGKYYCDYCDVFLvSESPSVRkAHNSGRNHLTNVRDY 37
Cdd:smart00451   1 TGGFYCKLCNVTF-TDEISVE-AHLKGKKHKKNVKKR 35
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 70-179 1.21e-05

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 44.80  E-value: 1.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508   70 PGGNP-PGSQPGPPNAGMSGPMRPPfSNSTAGPNMPPLPPAMlalmngqngmsSPGSGPPPMRFAGPP------------ 136
Cdd:TIGR01628 386 PMGSPmGGAMGQPPYYGQGPQQQFN-GQPLGWPRMSMMPTPM-----------GPGGPLRPNGLAPMNavrapsrnaqna 453

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 363805508  137 IPNNMPPGMMQPPHVNGYSSGPLPPQPQPASGGQGAPPLTARM 179
Cdd:TIGR01628 454 AQKPPMQPVMYPPNYQSLPLSQDLPQPQSTASQGGQNKKLAQV 496
PHA03247 PHA03247
large tegument protein UL36; Provisional
 62-173 1.76e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 1.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508   62 GNSTSNRGPGGNPPGSQPGPPNAGMSGPMRPPFSNSTAGPNMPPLPPAMLalmngqngmSSPGSGPPPMrfagPPIPNNM 141
Cdd:PHA03247 2859 GGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERP---------PQPQAPPPPQ----PQPQPPP 2925

                          90       100       110
                  ....*....|....*....|....*....|..
gi 363805508  142 PPGMMQPPHVNGYSSGPLPPQPQPASGGQGAP 173
Cdd:PHA03247 2926 PPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSG 2957
PHA03247 PHA03247
large tegument protein UL36; Provisional
 70-186 2.16e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.16  E-value: 2.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508   70 PGGNPPGSQPGPPNAGMSGPM--------RPPFSNSTAGPNMPPLPPAmlalmngqNGMSSPGSGPPPMRFAGPPIPNNM 141
Cdd:PHA03247 2836 PTAPPPPPGPPPPSLPLGGSVapggdvrrRPPSRSPAAKPAAPARPPV--------RRLARPAVSRSTESFALPPDQPER 2907

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 363805508  142 PPGMMQPPHVNGYSSGPLPPQPQPASGGQGAPPLTARMNPDRARQ 186
Cdd:PHA03247 2908 PPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGA 2952
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 60-186 4.78e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 4.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508  60 GGGNSTSNRGPGGNPPGSQPGPPNAGMSGPMRPPFSNSTAGPNMPPLPPAMLALMNGQNGMSSPGSG-----PPPMRFAG 134
Cdd:PRK07764 668 GWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAaddpvPLPPEPDD 747

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 363805508 135 PPIPNNMPPGMMQPPHVNGYSSGPLPPQPQPASGGQGAPPLTARMNPDRARQ 186
Cdd:PRK07764 748 PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRR 799
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 64-178 6.40e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 39.70  E-value: 6.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508  64 STSNRGPGGNPPGSQPGPPNAGMSGPMRPPFSNSTAGPNMPPLPPAMLALMNGQNGMSSPGSGPPPMRFAGPPIPNNMPP 143
Cdd:PRK14951 379 KTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPE 458

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 363805508 144 GMMQPPHVngySSGPLPPQPQPASGGQGAPPLTAR 178
Cdd:PRK14951 459 TVAIPVRV---APEPAVASAAPAPAAAPAAARLTP 490
PHA03378 PHA03378
EBNA-3B; Provisional
 74-173 9.80e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 39.28  E-value: 9.80e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508  74 PPGSQPGP--PNAGMSGPMRPPFSNSTagpnmpPLPPAMLALMNGQNGMSSPGSGPPPMRFAGPPIPNNMPPGMMQPPHV 151
Cdd:PHA03378 696 PPPRAPTPmrPPAAPPGRAQRPAAATG------RARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAA 769

                         90       100
                 ....*....|....*....|....*
gi 363805508 152 NGYSSGPLPPQ---PQPASGGQGAP 173
Cdd:PHA03378 770 APGAPTPQPPPqapPAPQQRPRGAP 794
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
25-185 1.16e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.09  E-value: 1.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508  25 NSGRNHLtnvrdyysSLGHDKAQSYIDEITRM--FETGGGNSTSNRGPGGNPPGSQPGPPNAGMSGPMRPPFSNSTAGPN 102
Cdd:PRK12323 337 NLGRSEL--------ALAPDEYAGFTMTLLRMlaFRPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAA 408

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508 103 MPPLPPAMLALMNGQNGMSSPGSGPPPMRFAGPPIPNNMPPGMMQPPHVngyssgPLPPQPQPASGGQGAPPLTARMNPD 182
Cdd:PRK12323 409 APAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAA------PAAAARPAAAGPRPVAAAAAAAPAR 482


                 ...
gi 363805508 183 RAR 185
Cdd:PRK12323 483 AAP 485
hnRNP-L_PTB TIGR01649
hnRNP-L/PTB/hephaestus splicing factor family; Included in this family of heterogeneous ...
 91-183 1.41e-03

hnRNP-L/PTB/hephaestus splicing factor family; Included in this family of heterogeneous ribonucleoproteins are PTB (polypyrimidine tract binding protein) and hnRNP-L. These proteins contain four RNA recognition motifs (rrm: pfam00067).


Pssm-ID: 273733 [Multi-domain]  Cd Length: 481  Bit Score: 38.64  E-value: 1.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508   91 RPPFSNSTAGPNMPPLPPAMLALMnGQNGMSSPGSGPPPM---RFAGPPIPNNMPPgmmqPPHVNGYSSGPLPPQPQPAS 167
Cdd:TIGR01649 197 RDPGLDQTHRQRQPALLGQHPSSY-GHDGYSSHGGPLAPLaggDRMGPPHGPPSRY----RPAYEAAPLAPAISSYGPAG 271

                          90       100
                  ....*....|....*....|.
gi 363805508  168 GGQGAPPLTA-----RMNPDR 183
Cdd:TIGR01649 272 GGPGSVLMVSglhqeKVNCDR 292
PHA03247 PHA03247
large tegument protein UL36; Provisional
 70-178 1.71e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.38  E-value: 1.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508   70 PGGNP-PGSQPGPPNAGMSGPMRPPFSNSTAGPNMPPLPPAMLALMNGQNGMSSPGSGPPPmrfagPPIPNNMPPGmmqP 148
Cdd:PHA03247 2492 AGAAPdPGGGGPPDPDAPPAPSRLAPAILPDEPVGEPVHPRMLTWIRGLEELASDDAGDPP-----PPLPPAAPPA---A 2563

                          90       100       110
                  ....*....|....*....|....*....|....
gi 363805508  149 PHVNGYSSGPLPPQPQPASGGQ----GAPPLTAR 178
Cdd:PHA03247 2564 PDRSVPPPRPAPRPSEPAVTSRarrpDAPPQSAR 2597
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
57-143 3.18e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 37.63  E-value: 3.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508  57 FETGGGNSTSNRGPggnPPGSQPGPPNAGMSGPMRPPFSNSTAGPNMPPLPPAMLALMNGQNGMSSPGSGPPPMrfagPP 136
Cdd:PRK14948 510 LESQSGSASNTAKT---PPPPQKSPPPPAPTPPLPQPTATAPPPTPPPPPPTATQASSNAPAQIPADSSPPPPI----PE 582


                 ....*..
gi 363805508 137 IPNNMPP 143
Cdd:PRK14948 583 EPTPSPT 589
PHA03369 PHA03369
capsid maturational protease; Provisional
 27-171 6.09e-03

capsid maturational protease; Provisional


Pssm-ID: 223061 [Multi-domain]  Cd Length: 663  Bit Score: 36.90  E-value: 6.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508  27 GRNHLTNVRDYYSSLGHDKAQSYIDEITRMFETGGGNSTSNRGPGGNPPGSQPGPpnAGMSGPMRPPFSNSTAGPNMPPL 106
Cdd:PHA03369 324 IEQYLIEGRKLFSTINGLKAHNEILKTASLTAPSRVLAAAAKVAVIAAPQTHTGP--ADRQRPQRPDGIPYSVPARSPMT 401

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 363805508 107 PPAMLALMNGQNGMSSPGSGPPPMRFAGPPIPNNMPPgmmQPPHV----NGYSSGPLPPQPQPASGGQG 171
Cdd:PHA03369 402 AYPPVPQFCGDPGLVSPYNPQSPGTSYGPEPVGPVPP---QPTNPyvmpISMANMVYPGHPQEHGHERK 467
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 74-177 7.40e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 36.62  E-value: 7.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508  74 PPGSQPGPPNAGMSGPMRPPFSNSTAGPnmPPLPPAMLALMNGQNGMSSPGSGPPPMRFAGPPIPNNMPPGMMQPPHVNG 153
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAP--VAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPA 443

                         90       100
                 ....*....|....*....|....
gi 363805508 154 YSSGPLPPQPQPASGGQGAPPLTA 177
Cdd:PRK14951 444 AVALAPAPPAQAAPETVAIPVRVA 467
PHA03247 PHA03247
large tegument protein UL36; Provisional
 59-187 8.39e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 36.45  E-value: 8.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508   59 TGGGNSTSNRGPGGNPPGSQPGPPNAGMSgpmrpPFSNSTAGPNMPPLPPAMLALMNGQNGMSSPGSGPPPMRFAGPPIP 138
Cdd:PHA03247 2764 AGPPAPAPPAAPAAGPPRRLTRPAVASLS-----ESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTA 2838

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 363805508  139 NNMPPGMMQPPHVNGYSSGPLPPQPQPASGGQGAPPLTARMNPdRARQL 187
Cdd:PHA03247 2839 PPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARP-PVRRL 2886
PHA03378 PHA03378
EBNA-3B; Provisional
 74-168 9.70e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 36.20  E-value: 9.70e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 363805508  74 PPGSQPGP--PNAGMSGPMRPPFSNSTAGPNMP----PLPPAMLALMNGQNGMSSPGSGPPPMRFAGPPIPNNMPPGmmq 147
Cdd:PHA03378 706 PPAAPPGRaqRPAAATGRARPPAAAPGRARPPAaapgRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQA--- 782

                         90       100
                 ....*....|....*....|.
gi 363805508 148 PPHVNGYSSGPLPPQPQPASG 168
Cdd:PHA03378 783 PPAPQQRPRGAPTPQPPPQAG 803
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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