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Conserved domains on  [gi|338817732|sp|E7KB73|]
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RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit CNL1; Short=BLOC-1 subunit CNL1; AltName: Full=CNO-like protein 1

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BLOC1_CNL1 cd24144
Biogenesis of lysosome-related organelles complex 1 subunit CNL1; Biogenesis of ...
 17-103 1.03e-45

Biogenesis of lysosome-related organelles complex 1 subunit CNL1; Biogenesis of lysosome-related organelles complex 1 (BLOC-1) subunit CNL1, also called CNO-like protein 1, is part of a complex that is involved in endosomal cargo sorting. BLOC-1 is an endosomal Rab-GAP (GTPase-activating protein) adapter complex that is composed of at least BLI1, BLS1, CNL1, KXD1, SNN1 and VAB2. Saccharomyces cerevisiae CLN1 is believed to be the homolog to the cappuccino (cno) subunit of the BLOC-1 complex in higher eukaryotes.


:

Pssm-ID: 467944  Cd Length: 87  Bit Score: 142.79  E-value: 1.03e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817732  17 DPLGIDKLTVDYDYLLYKIRDYVQSIQLDTTELCKKQNEVMVNGIIENTIDKNIAKFKELLEKCDTLENHYEMLNQLAII 96
Cdd:cd24144    1 DPLGIDKLSVDYDYLLYKIKDYVESIQLQTTEVCQKQNELVQYGIIELIIDQNIEKFKELLKKCDELENHFEMLDQLDII 80


                 ....*..
gi 338817732  97 TDTFKER 103
Cdd:cd24144   81 VDTFKER 87
 
Name Accession Description Interval E-value
BLOC1_CNL1 cd24144
Biogenesis of lysosome-related organelles complex 1 subunit CNL1; Biogenesis of ...
 17-103 1.03e-45

Biogenesis of lysosome-related organelles complex 1 subunit CNL1; Biogenesis of lysosome-related organelles complex 1 (BLOC-1) subunit CNL1, also called CNO-like protein 1, is part of a complex that is involved in endosomal cargo sorting. BLOC-1 is an endosomal Rab-GAP (GTPase-activating protein) adapter complex that is composed of at least BLI1, BLS1, CNL1, KXD1, SNN1 and VAB2. Saccharomyces cerevisiae CLN1 is believed to be the homolog to the cappuccino (cno) subunit of the BLOC-1 complex in higher eukaryotes.


Pssm-ID: 467944  Cd Length: 87  Bit Score: 142.79  E-value: 1.03e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817732  17 DPLGIDKLTVDYDYLLYKIRDYVQSIQLDTTELCKKQNEVMVNGIIENTIDKNIAKFKELLEKCDTLENHYEMLNQLAII 96
Cdd:cd24144    1 DPLGIDKLSVDYDYLLYKIKDYVESIQLQTTEVCQKQNELVQYGIIELIIDQNIEKFKELLKKCDELENHFEMLDQLDII 80


                 ....*..
gi 338817732  97 TDTFKER 103
Cdd:cd24144   81 VDTFKER 87
 
Name Accession Description Interval E-value
BLOC1_CNL1 cd24144
Biogenesis of lysosome-related organelles complex 1 subunit CNL1; Biogenesis of ...
 17-103 1.03e-45

Biogenesis of lysosome-related organelles complex 1 subunit CNL1; Biogenesis of lysosome-related organelles complex 1 (BLOC-1) subunit CNL1, also called CNO-like protein 1, is part of a complex that is involved in endosomal cargo sorting. BLOC-1 is an endosomal Rab-GAP (GTPase-activating protein) adapter complex that is composed of at least BLI1, BLS1, CNL1, KXD1, SNN1 and VAB2. Saccharomyces cerevisiae CLN1 is believed to be the homolog to the cappuccino (cno) subunit of the BLOC-1 complex in higher eukaryotes.


Pssm-ID: 467944  Cd Length: 87  Bit Score: 142.79  E-value: 1.03e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817732  17 DPLGIDKLTVDYDYLLYKIRDYVQSIQLDTTELCKKQNEVMVNGIIENTIDKNIAKFKELLEKCDTLENHYEMLNQLAII 96
Cdd:cd24144    1 DPLGIDKLSVDYDYLLYKIKDYVESIQLQTTEVCQKQNELVQYGIIELIIDQNIEKFKELLKKCDELENHFEMLDQLDII 80


                 ....*..
gi 338817732  97 TDTFKER 103
Cdd:cd24144   81 VDTFKER 87
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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