|
Name |
Accession |
Description |
Interval |
E-value |
| VI_ClpV1 |
TIGR03345 |
type VI secretion ATPase, ClpV1 family; Members of this protein family are homologs of ClpB, ... |
14-861 |
0e+00 |
|
type VI secretion ATPase, ClpV1 family; Members of this protein family are homologs of ClpB, an ATPase associated with chaperone-related functions. These ClpB homologs, designated ClpV1, are a key component of the bacterial pathogenicity-associated type VI secretion system. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274528 [Multi-domain] Cd Length: 852 Bit Score: 1128.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 14 LAPNVKTSLEQAAGDCVNQGHYAIELEHWFIQMLQLPGQGWSAAVDKVSIAKESLVEQLKDRLSTLSRGNDTSPSLSPQL 93
Cdd:TIGR03345 1 LNPTSRRALEQAAALCVARGHPEVELEHWLLALLDQPDSDLAAILRHFGVDLGRLKADLARALDKLPRGNTRTPVFSPHL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 94 VEVIKDAWMIASLNHAQSVVNEYHILLVLKQRLDQGAYNGPLSVWLKALSTEWLRAQAQV---TSKPSSQAASFAQNMEP 170
Cdd:TIGR03345 81 VELLQEAWLLASLELGDGRIRSGHLLLALLTDPELRRLLGSISPELAKIDREALREALPAlveGSAEASAAAADAAPAGA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 171 AFNDAGTPALDKYSQNLTQSARDGKIDPISGRGDEIRKSIDILCRRRQNSPILVGDPGVGKTAIVEGLAQQIVDGNVPPV 250
Cdd:TIGR03345 161 AAGAAGTSALDQYTTDLTAQAREGKIDPVLGRDDEIRQMIDILLRRRQNNPILTGEAGVGKTAVVEGLALRIAAGDVPPA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 251 LKNVELRSLDLSLLQAGASIKGEFENRLKDVINEIKQSETPIIMFIDEAHTLIGAGGAAGQNDAANILKPALARGEFRSL 330
Cdd:TIGR03345 241 LRNVRLLSLDLGLLQAGASVKGEFENRLKSVIDEVKASPQPIILFIDEAHTLIGAGGQAGQGDAANLLKPALARGELRTI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 331 AATTWAEYKQYFETDAALTRRFQVVAVGEPNETDAVHMLRGVKKSLEKHHNVKVMQEAIDAAVSLSIRYLPERQLPDKAI 410
Cdd:TIGR03345 321 AATTWAEYKKYFEKDPALTRRFQVVKVEEPDEETAIRMLRGLAPVLEKHHGVLILDEAVVAAVELSHRYIPGRQLPDKAV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 411 SLLDTACSRIGLSQSATPSQLEAIEEKIQYTRNEIDTLLHESALWSIEDERLGLAQEALLELEQNRKDLADRWEQEKSSV 490
Cdd:TIGR03345 401 SLLDTACARVALSQNATPAALEDLRRRIAALELELDALEREAALGADHDERLAELRAELAALEAELAALEARWQQEKELV 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 491 ELIIELQTELDSLYVSGEDiSSHASKTQLASEMDKLRELQGEQPLVLPQVCHQTIAEVVALWTGVPVGNMLSGEVDCLMH 570
Cdd:TIGR03345 481 EAILALRAELEADADAPAD-DDDALRAQLAELEAALASAQGEEPLVFPEVDAQAVAEVVADWTGIPVGRMVRDEIEAVLS 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 571 LEDKIGERVIGQTTPIAEISQAIRMSRAGLTDPRKPVGVFLMCGPSGVGKTETALALTDLLYGGERNVTTINMTEFKEEH 650
Cdd:TIGR03345 560 LPDRLAERVIGQDHALEAIAERIRTARAGLEDPRKPLGVFLLVGPSGVGKTETALALAELLYGGEQNLITINMSEFQEAH 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 651 KVSMLLGSPAGYVGYGKGGVLTEAVRKNPYSVLLLDEMEKAHPGVHDIFYQIFDKGSISDSEGRNIDFRNTIIIMTSNAA 730
Cdd:TIGR03345 640 TVSRLKGSPPGYVGYGEGGVLTEAVRRKPYSVVLLDEVEKAHPDVLELFYQVFDKGVMEDGEGREIDFKNTVILLTSNAG 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 731 DSAVVNACAQ--ERPAVPELTQTIFPELQKFFKPAFLGRATIVPYFPLNDNEMAQIAKLSLRRIERRVREHYSASFEYSL 808
Cdd:TIGR03345 720 SDLIMALCADpeTAPDPEALLEALRPELLKVFKPAFLGRMTVIPYLPLDDDVLAAIVRLKLDRIARRLKENHGAELVYSE 799
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|...
gi 84377691 809 QVIELLVQLNQSPETGARAIEQLINRKLMPELANNCIVKMSNAEPVNSVCVSV 861
Cdd:TIGR03345 800 ALVEHIVARCTEVESGARNIDAILNQTLLPELSRQILERLAAGEPIERIHLDV 852
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
1-866 |
0e+00 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 971.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 1 MMINielqslvkRLAPNVKTSLEQAAGDCVNQGHYAIELEHWFIQMLQLPGQGWSAAVDKVSIAKESLVEQLKDRLSTLS 80
Cdd:COG0542 1 MNFE--------KFTEKAQEALEAAQELARRLGHQEVEPEHLLLALLEQGEGLAAKLLRKLGVDLDALREELEEALGRLP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 81 R--GNDTSPSLSPQLVEVIKDAWMIASLNHaQSVVNEYHILLVLkqrLDQGayNGPLSVWLKA--LSTEWLRAQAQVTSK 156
Cdd:COG0542 73 KvsGSSGQPYLSPRLKRVLELAELEARKLG-DEYISTEHLLLAL---LREG--EGVAARILKKlgITLEALREALEELRG 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 157 PSSQAASFAQnmepafndAGTPALDKYSQNLTQSARDGKIDPISGRGDEIRKSIDILCRRRQNSPILVGDPGVGKTAIVE 236
Cdd:COG0542 147 GSRVTSQNPE--------SKTPALDKYGRDLTELAREGKLDPVIGRDEEIRRVIQILSRRTKNNPVLIGEPGVGKTAIVE 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 237 GLAQQIVDGNVPPVLKNVELRSLDLSLLQAGASIKGEFENRLKDVINEIKQSETPIIMFIDEAHTLIGAGGAAGQNDAAN 316
Cdd:COG0542 219 GLAQRIVNGDVPESLKDKRVLSLDLGALVAGAKYRGEFEERLKAVLDEVKKSEGNIILFIDELHTLVGAGGAEGAMDAAN 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 317 ILKPALARGEFRSLAATTWAEYKQYFETDAALTRRFQVVAVGEPNETDAVHMLRGVKKSLEKHHNVKVMQEAIDAAVSLS 396
Cdd:COG0542 299 LLKPALARGELRCIGATTLDEYRKYIEKDAALERRFQPVLVEEPSVEDTISILRGLKERYEAHHGVRITDEALVAAVRLS 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 397 IRYLPERQLPDKAISLLDTACSRIGLSQSATPSQLEAIEEKIQYTRNEIDTLLHESALWSieDERLGLAQEALLELEQNR 476
Cdd:COG0542 379 DRYITDRFLPDKAIDLIDEAAARVRMEIDSKPEELDELERRLEQLEIEKEALKKEQDEAS--FERLAELRDELAELEEEL 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 477 KDLADRWEQEKSSVELIIELQTELDSLYvsgEDISSHASKTQLASEmdklrELQGEQPLVLPQVCHQTIAEVVALWTGVP 556
Cdd:COG0542 457 EALKARWEAEKELIEEIQELKEELEQRY---GKIPELEKELAELEE-----ELAELAPLLREEVTEEDIAEVVSRWTGIP 528
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 557 VGNMLSGEVDCLMHLEDKIGERVIGQTTPIAEISQAIRMSRAGLTDPRKPVGVFLMCGPSGVGKTETALALTDLLYGGER 636
Cdd:COG0542 529 VGKLLEGEREKLLNLEEELHERVIGQDEAVEAVADAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELAKALAEFLFGDED 608
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 637 NVTTINMTEFKEEHKVSMLLGSPagyvgygkggVLTEAVRKNPYSVLLLDEMEKAHPGVHDIFYQIFDKGSISDSEGRNI 716
Cdd:COG0542 609 ALIRIDMSEYMEKHSVSRLIGAPpgyvgyeeggQLTEAVRRRPYSVVLLDEIEKAHPDVFNILLQVLDDGRLTDGQGRTV 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 717 DFRNTIIIMTSNAADSAVVNACAQErPAVPELTQTIFPELQKFFKPAFLGR-ATIVPYFPLNDNEMAQIAKLSLRRIERR 795
Cdd:COG0542 689 DFRNTIIIMTSNIGSELILDLAEDE-PDYEEMKEAVMEELKKHFRPEFLNRiDEIIVFHPLSKEELRKIVDLQLKRLRKR 767
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 84377691 796 VREHySASFEYSLQVIELLVQLNQSPETGARAIEQLINRKLMPELANNCIVKMSNAEPVnsVCVSVVDTQF 866
Cdd:COG0542 768 LAER-GITLELTDAAKDFLAEKGYDPEYGARPLKRAIQRELEDPLAEEILAGEIKEGDT--ITVDVDDGEL 835
|
|
| clpC |
CHL00095 |
Clp protease ATP binding subunit |
170-845 |
0e+00 |
|
Clp protease ATP binding subunit
Pssm-ID: 214361 [Multi-domain] Cd Length: 821 Bit Score: 550.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 170 PAFNDAGTPALDKYSQNLTQSARDGKIDPISGRGDEIRKSIDILCRRRQNSPILVGDPGVGKTAIVEGLAQQIVDGNVPP 249
Cdd:CHL00095 152 AEQSRSKTPTLEEFGTNLTKEAIDGNLDPVIGREKEIERVIQILGRRTKNNPILIGEPGVGKTAIAEGLAQRIVNRDVPD 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 250 VLKNVELRSLDLSLLQAGASIKGEFENRLKDVINEIKQSETpIIMFIDEAHTLIGAGGAAGQNDAANILKPALARGEFRS 329
Cdd:CHL00095 232 ILEDKLVITLDIGLLLAGTKYRGEFEERLKRIFDEIQENNN-IILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQC 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 330 LAATTWAEYKQYFETDAALTRRFQVVAVGEPNETDAVHMLRGVKKSLEKHHNVKVMQEAIDAAVSLSIRYLPERQLPDKA 409
Cdd:CHL00095 311 IGATTLDEYRKHIEKDPALERRFQPVYVGEPSVEETIEILFGLRSRYEKHHNLSISDKALEAAAKLSDQYIADRFLPDKA 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 410 ISLLDTACSRIGLSQSATPSQLeaieekiqytrNEIDTLLHESalwsiederlglaqealleleQNRKDLADRwEQEKSS 489
Cdd:CHL00095 391 IDLLDEAGSRVRLINSRLPPAA-----------RELDKELREI---------------------LKDKDEAIR-EQDFET 437
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 490 VELIIELQTELdslyvsgedisshasKTQLASeMDKLRELQGEQPLVLPQVCHQTIAEVVALWTGVPVGNMLSGEVDCLM 569
Cdd:CHL00095 438 AKQLRDREMEV---------------RAQIAA-IIQSKKTEEEKRLEVPVVTEEDIAEIVSAWTGIPVNKLTKSESEKLL 501
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 570 HLEDKIGERVIGQTTPIAEISQAIRMSRAGLTDPRKPVGVFLMCGPSGVGKTETALALTDLLYGGERNVTTINMTEFKEE 649
Cdd:CHL00095 502 HMEETLHKRIIGQDEAVVAVSKAIRRARVGLKNPNRPIASFLFSGPTGVGKTELTKALASYFFGSEDAMIRLDMSEYMEK 581
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 650 HKVSMLLGSPAGYVGYGKGGVLTEAVRKNPYSVLLLDEMEKAHPGVHDIFYQIFDKGSISDSEGRNIDFRNTIIIMTSNA 729
Cdd:CHL00095 582 HTVSKLIGSPPGYVGYNEGGQLTEAVRKKPYTVVLFDEIEKAHPDIFNLLLQILDDGRLTDSKGRTIDFKNTLIIMTSNL 661
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 730 ADSAVVN--ACAQERPAVPELTQTIFP--------ELQKFFKPAFLGRA-TIVPYFPLNDNEMAQIAKLSLRRIERRVRE 798
Cdd:CHL00095 662 GSKVIETnsGGLGFELSENQLSEKQYKrlsnlvneELKQFFRPEFLNRLdEIIVFRQLTKNDVWEIAEIMLKNLFKRLNE 741
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|.
gi 84377691 799 HySASFEYSLQVIELLVQLNQSPETGA----RAIEQLINRKLMPELANNCI 845
Cdd:CHL00095 742 Q-GIQLEVTERIKTLLIEEGYNPLYGArplrRAIMRLLEDPLAEEVLSFKI 791
|
|
| RecA-like_ClpB_Hsp104-like |
cd19499 |
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ... |
567-774 |
2.86e-74 |
|
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410907 [Multi-domain] Cd Length: 178 Bit Score: 240.54 E-value: 2.86e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 567 CLMHLEDKIGERVIGQTTPIAEISQAIRMSRAGLTDPRKPVGVFLMCGPSGVGKTETALALTDLLYGGERNVTTINMTEF 646
Cdd:cd19499 1 KLLNLEERLHERVVGQDEAVKAVSDAIRRARAGLSDPNRPIGSFLFLGPTGVGKTELAKALAELLFGDEDNLIRIDMSEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 647 KEEHKVSMLLGSPAGYVGYGKGGVLTEAVRKNPYSVLLLDEMEKAHPGVHDIFYQIFDKGSISDSEGRNIDFRNTIIIMT 726
Cdd:cd19499 81 MEKHSVSRLIGAPPGYVGYTEGGQLTEAVRRKPYSVVLLDEIEKAHPDVQNLLLQVLDDGRLTDSHGRTVDFKNTIIIMT 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 84377691 727 SNaadsavvnacaqerpavpeltqtifpelqkFFKPAFLGRATIVPYF 774
Cdd:cd19499 161 SN------------------------------HFRPEFLNRIDEIVVF 178
|
|
| AAA_2 |
pfam07724 |
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ... |
605-767 |
1.40e-59 |
|
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400187 [Multi-domain] Cd Length: 168 Bit Score: 200.11 E-value: 1.40e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 605 KPVGVFLMCGPSGVGKTETALALTDLLYGGERNVTTINMTEFKEEHKVSMLLGSPAGYVGYGKGGVLTEAVRKNPYSVLL 684
Cdd:pfam07724 1 RPIGSFLFLGPTGVGKTELAKALAELLFGDERALIRIDMSEYMEEHSVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSIVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 685 LDEMEKAHPGVHDIFYQIFDKGSISDSEGRNIDFRNTIIIMTSNAADSAVVNACAQERPAVPELTQT-IFPELQKFFKPA 763
Cdd:pfam07724 81 IDEIEKAHPGVQNDLLQILEGGTLTDKQGRTVDFKNTLFIMTGNFGSEKISDASRLGDSPDYELLKEeVMDLLKKGFIPE 160
|
....
gi 84377691 764 FLGR 767
Cdd:pfam07724 161 FLGR 164
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
608-728 |
2.68e-09 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 56.61 E-value: 2.68e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 608 GVFLMCGPSGVGKTETALALTDLLYGGERNVTTINMTEFKEEHKVSMLL----GSPAGYVGYGKGGVLTEAVRKNPYSVL 683
Cdd:smart00382 3 EVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLiivgGKKASGSGELRLRLALALARKLKPDVL 82
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 84377691 684 LLDEMEKAHPGVHDIFYQifdKGSISDSEGRNIDFRNTIIIMTSN 728
Cdd:smart00382 83 ILDEITSLLDAEQEALLL---LLEELRLLLLLKSEKNLTVILTTN 124
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| VI_ClpV1 |
TIGR03345 |
type VI secretion ATPase, ClpV1 family; Members of this protein family are homologs of ClpB, ... |
14-861 |
0e+00 |
|
type VI secretion ATPase, ClpV1 family; Members of this protein family are homologs of ClpB, an ATPase associated with chaperone-related functions. These ClpB homologs, designated ClpV1, are a key component of the bacterial pathogenicity-associated type VI secretion system. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274528 [Multi-domain] Cd Length: 852 Bit Score: 1128.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 14 LAPNVKTSLEQAAGDCVNQGHYAIELEHWFIQMLQLPGQGWSAAVDKVSIAKESLVEQLKDRLSTLSRGNDTSPSLSPQL 93
Cdd:TIGR03345 1 LNPTSRRALEQAAALCVARGHPEVELEHWLLALLDQPDSDLAAILRHFGVDLGRLKADLARALDKLPRGNTRTPVFSPHL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 94 VEVIKDAWMIASLNHAQSVVNEYHILLVLKQRLDQGAYNGPLSVWLKALSTEWLRAQAQV---TSKPSSQAASFAQNMEP 170
Cdd:TIGR03345 81 VELLQEAWLLASLELGDGRIRSGHLLLALLTDPELRRLLGSISPELAKIDREALREALPAlveGSAEASAAAADAAPAGA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 171 AFNDAGTPALDKYSQNLTQSARDGKIDPISGRGDEIRKSIDILCRRRQNSPILVGDPGVGKTAIVEGLAQQIVDGNVPPV 250
Cdd:TIGR03345 161 AAGAAGTSALDQYTTDLTAQAREGKIDPVLGRDDEIRQMIDILLRRRQNNPILTGEAGVGKTAVVEGLALRIAAGDVPPA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 251 LKNVELRSLDLSLLQAGASIKGEFENRLKDVINEIKQSETPIIMFIDEAHTLIGAGGAAGQNDAANILKPALARGEFRSL 330
Cdd:TIGR03345 241 LRNVRLLSLDLGLLQAGASVKGEFENRLKSVIDEVKASPQPIILFIDEAHTLIGAGGQAGQGDAANLLKPALARGELRTI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 331 AATTWAEYKQYFETDAALTRRFQVVAVGEPNETDAVHMLRGVKKSLEKHHNVKVMQEAIDAAVSLSIRYLPERQLPDKAI 410
Cdd:TIGR03345 321 AATTWAEYKKYFEKDPALTRRFQVVKVEEPDEETAIRMLRGLAPVLEKHHGVLILDEAVVAAVELSHRYIPGRQLPDKAV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 411 SLLDTACSRIGLSQSATPSQLEAIEEKIQYTRNEIDTLLHESALWSIEDERLGLAQEALLELEQNRKDLADRWEQEKSSV 490
Cdd:TIGR03345 401 SLLDTACARVALSQNATPAALEDLRRRIAALELELDALEREAALGADHDERLAELRAELAALEAELAALEARWQQEKELV 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 491 ELIIELQTELDSLYVSGEDiSSHASKTQLASEMDKLRELQGEQPLVLPQVCHQTIAEVVALWTGVPVGNMLSGEVDCLMH 570
Cdd:TIGR03345 481 EAILALRAELEADADAPAD-DDDALRAQLAELEAALASAQGEEPLVFPEVDAQAVAEVVADWTGIPVGRMVRDEIEAVLS 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 571 LEDKIGERVIGQTTPIAEISQAIRMSRAGLTDPRKPVGVFLMCGPSGVGKTETALALTDLLYGGERNVTTINMTEFKEEH 650
Cdd:TIGR03345 560 LPDRLAERVIGQDHALEAIAERIRTARAGLEDPRKPLGVFLLVGPSGVGKTETALALAELLYGGEQNLITINMSEFQEAH 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 651 KVSMLLGSPAGYVGYGKGGVLTEAVRKNPYSVLLLDEMEKAHPGVHDIFYQIFDKGSISDSEGRNIDFRNTIIIMTSNAA 730
Cdd:TIGR03345 640 TVSRLKGSPPGYVGYGEGGVLTEAVRRKPYSVVLLDEVEKAHPDVLELFYQVFDKGVMEDGEGREIDFKNTVILLTSNAG 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 731 DSAVVNACAQ--ERPAVPELTQTIFPELQKFFKPAFLGRATIVPYFPLNDNEMAQIAKLSLRRIERRVREHYSASFEYSL 808
Cdd:TIGR03345 720 SDLIMALCADpeTAPDPEALLEALRPELLKVFKPAFLGRMTVIPYLPLDDDVLAAIVRLKLDRIARRLKENHGAELVYSE 799
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|...
gi 84377691 809 QVIELLVQLNQSPETGARAIEQLINRKLMPELANNCIVKMSNAEPVNSVCVSV 861
Cdd:TIGR03345 800 ALVEHIVARCTEVESGARNIDAILNQTLLPELSRQILERLAAGEPIERIHLDV 852
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
1-866 |
0e+00 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 971.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 1 MMINielqslvkRLAPNVKTSLEQAAGDCVNQGHYAIELEHWFIQMLQLPGQGWSAAVDKVSIAKESLVEQLKDRLSTLS 80
Cdd:COG0542 1 MNFE--------KFTEKAQEALEAAQELARRLGHQEVEPEHLLLALLEQGEGLAAKLLRKLGVDLDALREELEEALGRLP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 81 R--GNDTSPSLSPQLVEVIKDAWMIASLNHaQSVVNEYHILLVLkqrLDQGayNGPLSVWLKA--LSTEWLRAQAQVTSK 156
Cdd:COG0542 73 KvsGSSGQPYLSPRLKRVLELAELEARKLG-DEYISTEHLLLAL---LREG--EGVAARILKKlgITLEALREALEELRG 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 157 PSSQAASFAQnmepafndAGTPALDKYSQNLTQSARDGKIDPISGRGDEIRKSIDILCRRRQNSPILVGDPGVGKTAIVE 236
Cdd:COG0542 147 GSRVTSQNPE--------SKTPALDKYGRDLTELAREGKLDPVIGRDEEIRRVIQILSRRTKNNPVLIGEPGVGKTAIVE 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 237 GLAQQIVDGNVPPVLKNVELRSLDLSLLQAGASIKGEFENRLKDVINEIKQSETPIIMFIDEAHTLIGAGGAAGQNDAAN 316
Cdd:COG0542 219 GLAQRIVNGDVPESLKDKRVLSLDLGALVAGAKYRGEFEERLKAVLDEVKKSEGNIILFIDELHTLVGAGGAEGAMDAAN 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 317 ILKPALARGEFRSLAATTWAEYKQYFETDAALTRRFQVVAVGEPNETDAVHMLRGVKKSLEKHHNVKVMQEAIDAAVSLS 396
Cdd:COG0542 299 LLKPALARGELRCIGATTLDEYRKYIEKDAALERRFQPVLVEEPSVEDTISILRGLKERYEAHHGVRITDEALVAAVRLS 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 397 IRYLPERQLPDKAISLLDTACSRIGLSQSATPSQLEAIEEKIQYTRNEIDTLLHESALWSieDERLGLAQEALLELEQNR 476
Cdd:COG0542 379 DRYITDRFLPDKAIDLIDEAAARVRMEIDSKPEELDELERRLEQLEIEKEALKKEQDEAS--FERLAELRDELAELEEEL 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 477 KDLADRWEQEKSSVELIIELQTELDSLYvsgEDISSHASKTQLASEmdklrELQGEQPLVLPQVCHQTIAEVVALWTGVP 556
Cdd:COG0542 457 EALKARWEAEKELIEEIQELKEELEQRY---GKIPELEKELAELEE-----ELAELAPLLREEVTEEDIAEVVSRWTGIP 528
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 557 VGNMLSGEVDCLMHLEDKIGERVIGQTTPIAEISQAIRMSRAGLTDPRKPVGVFLMCGPSGVGKTETALALTDLLYGGER 636
Cdd:COG0542 529 VGKLLEGEREKLLNLEEELHERVIGQDEAVEAVADAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELAKALAEFLFGDED 608
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 637 NVTTINMTEFKEEHKVSMLLGSPagyvgygkggVLTEAVRKNPYSVLLLDEMEKAHPGVHDIFYQIFDKGSISDSEGRNI 716
Cdd:COG0542 609 ALIRIDMSEYMEKHSVSRLIGAPpgyvgyeeggQLTEAVRRRPYSVVLLDEIEKAHPDVFNILLQVLDDGRLTDGQGRTV 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 717 DFRNTIIIMTSNAADSAVVNACAQErPAVPELTQTIFPELQKFFKPAFLGR-ATIVPYFPLNDNEMAQIAKLSLRRIERR 795
Cdd:COG0542 689 DFRNTIIIMTSNIGSELILDLAEDE-PDYEEMKEAVMEELKKHFRPEFLNRiDEIIVFHPLSKEELRKIVDLQLKRLRKR 767
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 84377691 796 VREHySASFEYSLQVIELLVQLNQSPETGARAIEQLINRKLMPELANNCIVKMSNAEPVnsVCVSVVDTQF 866
Cdd:COG0542 768 LAER-GITLELTDAAKDFLAEKGYDPEYGARPLKRAIQRELEDPLAEEILAGEIKEGDT--ITVDVDDGEL 835
|
|
| clpC |
CHL00095 |
Clp protease ATP binding subunit |
170-845 |
0e+00 |
|
Clp protease ATP binding subunit
Pssm-ID: 214361 [Multi-domain] Cd Length: 821 Bit Score: 550.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 170 PAFNDAGTPALDKYSQNLTQSARDGKIDPISGRGDEIRKSIDILCRRRQNSPILVGDPGVGKTAIVEGLAQQIVDGNVPP 249
Cdd:CHL00095 152 AEQSRSKTPTLEEFGTNLTKEAIDGNLDPVIGREKEIERVIQILGRRTKNNPILIGEPGVGKTAIAEGLAQRIVNRDVPD 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 250 VLKNVELRSLDLSLLQAGASIKGEFENRLKDVINEIKQSETpIIMFIDEAHTLIGAGGAAGQNDAANILKPALARGEFRS 329
Cdd:CHL00095 232 ILEDKLVITLDIGLLLAGTKYRGEFEERLKRIFDEIQENNN-IILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQC 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 330 LAATTWAEYKQYFETDAALTRRFQVVAVGEPNETDAVHMLRGVKKSLEKHHNVKVMQEAIDAAVSLSIRYLPERQLPDKA 409
Cdd:CHL00095 311 IGATTLDEYRKHIEKDPALERRFQPVYVGEPSVEETIEILFGLRSRYEKHHNLSISDKALEAAAKLSDQYIADRFLPDKA 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 410 ISLLDTACSRIGLSQSATPSQLeaieekiqytrNEIDTLLHESalwsiederlglaqealleleQNRKDLADRwEQEKSS 489
Cdd:CHL00095 391 IDLLDEAGSRVRLINSRLPPAA-----------RELDKELREI---------------------LKDKDEAIR-EQDFET 437
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 490 VELIIELQTELdslyvsgedisshasKTQLASeMDKLRELQGEQPLVLPQVCHQTIAEVVALWTGVPVGNMLSGEVDCLM 569
Cdd:CHL00095 438 AKQLRDREMEV---------------RAQIAA-IIQSKKTEEEKRLEVPVVTEEDIAEIVSAWTGIPVNKLTKSESEKLL 501
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 570 HLEDKIGERVIGQTTPIAEISQAIRMSRAGLTDPRKPVGVFLMCGPSGVGKTETALALTDLLYGGERNVTTINMTEFKEE 649
Cdd:CHL00095 502 HMEETLHKRIIGQDEAVVAVSKAIRRARVGLKNPNRPIASFLFSGPTGVGKTELTKALASYFFGSEDAMIRLDMSEYMEK 581
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 650 HKVSMLLGSPAGYVGYGKGGVLTEAVRKNPYSVLLLDEMEKAHPGVHDIFYQIFDKGSISDSEGRNIDFRNTIIIMTSNA 729
Cdd:CHL00095 582 HTVSKLIGSPPGYVGYNEGGQLTEAVRKKPYTVVLFDEIEKAHPDIFNLLLQILDDGRLTDSKGRTIDFKNTLIIMTSNL 661
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 730 ADSAVVN--ACAQERPAVPELTQTIFP--------ELQKFFKPAFLGRA-TIVPYFPLNDNEMAQIAKLSLRRIERRVRE 798
Cdd:CHL00095 662 GSKVIETnsGGLGFELSENQLSEKQYKrlsnlvneELKQFFRPEFLNRLdEIIVFRQLTKNDVWEIAEIMLKNLFKRLNE 741
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|.
gi 84377691 799 HySASFEYSLQVIELLVQLNQSPETGA----RAIEQLINRKLMPELANNCI 845
Cdd:CHL00095 742 Q-GIQLEVTERIKTLLIEEGYNPLYGArplrRAIMRLLEDPLAEEVLSFKI 791
|
|
| PRK10865 |
PRK10865 |
ATP-dependent chaperone ClpB; |
55-836 |
0e+00 |
|
ATP-dependent chaperone ClpB;
Pssm-ID: 182791 [Multi-domain] Cd Length: 857 Bit Score: 544.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 55 SAAVDKVSIAKEslVEQLKDRLSTLS-RGNDTSPSlsPQLVEVIKDAWMIASLNHAQSVVNEYHILLVLKQRldqgaynG 133
Cdd:PRK10865 52 SAGINAGQLRTD--INQALSRLPQVEgTGGDVQPS--QDLVRVLNLCDKLAQKRGDNFISSELFVLAALESR-------G 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 134 PLSVWLKAlstewlraqAQVTSKPSSQAASFAQNMEpAFNDAGTP----ALDKYSQNLTQSARDGKIDPISGRGDEIRKS 209
Cdd:PRK10865 121 TLADILKA---------AGATTANITQAIEQMRGGE-SVNDQGAEdqrqALKKYTIDLTERAEQGKLDPVIGRDEEIRRT 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 210 IDILCRRRQNSPILVGDPGVGKTAIVEGLAQQIVDGNVPPVLKNVELRSLDLSLLQAGASIKGEFENRLKDVINEIKQSE 289
Cdd:PRK10865 191 IQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQE 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 290 TPIIMFIDEAHTLIGAGGAAGQNDAANILKPALARGEFRSLAATTWAEYKQYFETDAALTRRFQVVAVGEPNETDAVHML 369
Cdd:PRK10865 271 GNVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQKVFVAEPSVEDTIAIL 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 370 RGVKKSLEKHHNVKVMQEAIDAAVSLSIRYLPERQLPDKAISLLDTACSRIGLSQSATPSQLEAIEEKIQYTRNEIDTLL 449
Cdd:PRK10865 351 RGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALM 430
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 450 HESALWSIedERLGLAQEALLELEQNRKDLADRWEQEKSSVELIIELQTELDSLYVSGEdisshasKTQLASEMDKLREL 529
Cdd:PRK10865 431 KESDEASK--KRLDMLNEELSDKERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIE-------QARRVGDLARMSEL 501
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 530 Q-GEQP------------------LVLPQVCHQTIAEVVALWTGVPVGNMLSGEVDCLMHLEDKIGERVIGQTTPIAEIS 590
Cdd:PRK10865 502 QyGKIPelekqlaaatqlegktmrLLRNKVTDAEIAEVLARWTGIPVSRMLESEREKLLRMEQELHHRVIGQNEAVEAVS 581
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 591 QAIRMSRAGLTDPRKPVGVFLMCGPSGVGKTETALALTDLLYGGERNVTTINMTEFKEEHKVSMLLGSPAGYVGYGKGGV 670
Cdd:PRK10865 582 NAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDDAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGY 661
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 671 LTEAVRKNPYSVLLLDEMEKAHPGVHDIFYQIFDKGSISDSEGRNIDFRNTIIIMTSNAADSAVvnacaQER---PAVPE 747
Cdd:PRK10865 662 LTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLI-----QERfgeLDYAH 736
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 748 LTQTIFPELQKFFKPAFLGRA-TIVPYFPLNDNEMAQIAKLSLRRIERRVREH-YSASFeySLQVIELLVQLNQSPETGA 825
Cdd:PRK10865 737 MKELVLGVVSHNFRPEFINRIdEVVVFHPLGEQHIASIAQIQLQRLYKRLEERgYEIHI--SDEALKLLSENGYDPVYGA 814
|
810
....*....|....*
gi 84377691 826 ----RAIEQLINRKL 836
Cdd:PRK10865 815 rplkRAIQQQIENPL 829
|
|
| clpA |
PRK11034 |
ATP-dependent Clp protease ATP-binding subunit; Provisional |
154-842 |
8.97e-119 |
|
ATP-dependent Clp protease ATP-binding subunit; Provisional
Pssm-ID: 236828 [Multi-domain] Cd Length: 758 Bit Score: 378.41 E-value: 8.97e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 154 TSKPSSQAASFAQNMEPAFNDAGTP-ALDKYSQNLTQSARDGKIDPISGRGDEIRKSIDILCRRRQNSPILVGDPGVGKT 232
Cdd:PRK11034 142 TRKDEPSQSSDPGSQPNSEEQAGGEeRMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKT 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 233 AIVEGLAQQIVDGNVPPVLKNVELRSLDLSLLQAGASIKGEFENRLKDVINEIKQsETPIIMFIDEAHTLIGAGGAA-GQ 311
Cdd:PRK11034 222 AIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQ-DTNSILFIDEIHTIIGAGAASgGQ 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 312 NDAANILKPALARGEFRSLAATTWAEYKQYFETDAALTRRFQVVAVGEPNETDAVHMLRGVKKSLEKHHNVKVMQEAIDA 391
Cdd:PRK11034 301 VDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRA 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 392 AVSLSIRYLPERQLPDKAISLLDTACSRIGLsqsaTPSqleaieekiqytrneidtllhesalwsiederlglaqealle 471
Cdd:PRK11034 381 AVELAVKYINDRHLPDKAIDVIDEAGARARL----MPV------------------------------------------ 414
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 472 leQNRKDLadrweqekssveliielqteldslyVSGEDISShasktqlasemdklrelqgeqplvlpqvchqtiaeVVAL 551
Cdd:PRK11034 415 --SKRKKT-------------------------VNVADIES-----------------------------------VVAR 432
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 552 WTGVPVGNMLSGEVDCLMHLEDKIGERVIGQTTPIAEISQAIRMSRAGLTDPRKPVGVFLMCGPSGVGKTETALALTDLL 631
Cdd:PRK11034 433 IARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMSRAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKAL 512
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 632 yGGErnVTTINMTEFKEEHKVSMLLGSPAGYVGYGKGGVLTEAVRKNPYSVLLLDEMEKAHPGVHDIFYQIFDKGSISDS 711
Cdd:PRK11034 513 -GIE--LLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNLLLQVMDNGTLTDN 589
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 712 EGRNIDFRNTIIIMTSNAAdsavvnACAQERPAVPELTQ----TIFPELQKFFKPAFLGRATIVPYFPLNDNEMAQ---- 783
Cdd:PRK11034 590 NGRKADFRNVVLVMTTNAG------VRETERKSIGLIHQdnstDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHqvvd 663
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 84377691 784 --IAKLSLRRIERRVrehysaSFEYSLQVIELLVQLNQSPETGARAIEQLINRKLMPELAN 842
Cdd:PRK11034 664 kfIVELQAQLDQKGV------SLEVSQEARDWLAEKGYDRAMGARPMARVIQDNLKKPLAN 718
|
|
| RecA-like_ClpB_Hsp104-like |
cd19499 |
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ... |
567-774 |
2.86e-74 |
|
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410907 [Multi-domain] Cd Length: 178 Bit Score: 240.54 E-value: 2.86e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 567 CLMHLEDKIGERVIGQTTPIAEISQAIRMSRAGLTDPRKPVGVFLMCGPSGVGKTETALALTDLLYGGERNVTTINMTEF 646
Cdd:cd19499 1 KLLNLEERLHERVVGQDEAVKAVSDAIRRARAGLSDPNRPIGSFLFLGPTGVGKTELAKALAELLFGDEDNLIRIDMSEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 647 KEEHKVSMLLGSPAGYVGYGKGGVLTEAVRKNPYSVLLLDEMEKAHPGVHDIFYQIFDKGSISDSEGRNIDFRNTIIIMT 726
Cdd:cd19499 81 MEKHSVSRLIGAPPGYVGYTEGGQLTEAVRRKPYSVVLLDEIEKAHPDVQNLLLQVLDDGRLTDSHGRTVDFKNTIIIMT 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 84377691 727 SNaadsavvnacaqerpavpeltqtifpelqkFFKPAFLGRATIVPYF 774
Cdd:cd19499 161 SN------------------------------HFRPEFLNRIDEIVVF 178
|
|
| AAA_2 |
pfam07724 |
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ... |
605-767 |
1.40e-59 |
|
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400187 [Multi-domain] Cd Length: 168 Bit Score: 200.11 E-value: 1.40e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 605 KPVGVFLMCGPSGVGKTETALALTDLLYGGERNVTTINMTEFKEEHKVSMLLGSPAGYVGYGKGGVLTEAVRKNPYSVLL 684
Cdd:pfam07724 1 RPIGSFLFLGPTGVGKTELAKALAELLFGDERALIRIDMSEYMEEHSVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSIVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 685 LDEMEKAHPGVHDIFYQIFDKGSISDSEGRNIDFRNTIIIMTSNAADSAVVNACAQERPAVPELTQT-IFPELQKFFKPA 763
Cdd:pfam07724 81 IDEIEKAHPGVQNDLLQILEGGTLTDKQGRTVDFKNTLFIMTGNFGSEKISDASRLGDSPDYELLKEeVMDLLKKGFIPE 160
|
....
gi 84377691 764 FLGR 767
Cdd:pfam07724 161 FLGR 164
|
|
| AAA_lid_9 |
pfam17871 |
AAA lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the ... |
364-453 |
1.24e-36 |
|
AAA lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the C-terminus of AAA domains.
Pssm-ID: 465544 [Multi-domain] Cd Length: 104 Bit Score: 133.00 E-value: 1.24e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 364 DAVHMLRGVKKSLEKHHNVKVMQEAIDAAVSLSIRYLPERQLPDKAISLLDTACSRIGLSQSATPSQLEAIEEKIQYTRN 443
Cdd:pfam17871 4 EAIEILRGLKPKYEKHHGVRISDEALEAAVKLSKRYITDRFLPDKAIDLLDEACARVRLSQESKPEELEDLERELAKLEI 83
|
90
....*....|
gi 84377691 444 EIDTLLHESA 453
Cdd:pfam17871 84 EKEALEREQD 93
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
201-360 |
3.55e-16 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 76.42 E-value: 3.55e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 201 GRGDEIRKSIDILCRRRQNSPILVGDPGVGKTAIVEGLAQQIVDGNVPPVlknvelrSLDLSLLQAGASIKGEFENRLKD 280
Cdd:cd00009 2 GQEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFL-------YLNASDLLEGLVVAELFGHFLVR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 281 VINEIKQSETPIIMFIDEAHTLIGAGGAAGQNDAANILKPALARGEFRSLAATTwaeYKQYFETDAALTRRFQVVAVGEP 360
Cdd:cd00009 75 LLFELAEKAKPGVLFIDEIDSLSRGAQNALLRVLETLNDLRIDRENVRVIGATN---RPLLGDLDRALYDRLDIRIVIPL 151
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
603-732 |
1.71e-14 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 71.79 E-value: 1.71e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 603 PRKPVGVFLMCGPSGVGKTETALALTDLLYGGERNVTTINMTEFKEEHKVSMLLGSPAgyvgygkGGVLTEAVRKNPYSV 682
Cdd:cd00009 15 ELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHFL-------VRLLFELAEKAKPGV 87
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 84377691 683 LLLDEMEKAHPGVHDIFYQIFDKGSISdsegrNIDFRNTIIIMTSNAADS 732
Cdd:cd00009 88 LFIDEIDSLSRGAQNALLRVLETLNDL-----RIDRENVRVIGATNRPLL 132
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
222-355 |
8.49e-12 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 63.38 E-value: 8.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 222 ILVGDPGVGKTAIVEGLAQQIvdgnvppvlkNVELRSLDLSLLqaGASIKGEFENRLKDVINEIKqSETPIIMFIDEAHT 301
Cdd:pfam00004 2 LLYGPPGTGKTTLAKAVAKEL----------GAPFIEISGSEL--VSKYVGESEKRLRELFEAAK-KLAPCVIFIDEIDA 68
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 84377691 302 LIGAGGAAGQ---NDAANILKPALARGEFRS-----LAATTwaeykQYFETDAALTRRFQVV 355
Cdd:pfam00004 69 LAGSRGSGGDsesRRVVNQLLTELDGFTSSNskvivIAATN-----RPDKLDPALLGRFDRI 125
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
608-728 |
2.68e-09 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 56.61 E-value: 2.68e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 608 GVFLMCGPSGVGKTETALALTDLLYGGERNVTTINMTEFKEEHKVSMLL----GSPAGYVGYGKGGVLTEAVRKNPYSVL 683
Cdd:smart00382 3 EVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLiivgGKKASGSGELRLRLALALARKLKPDVL 82
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 84377691 684 LLDEMEKAHPGVHDIFYQifdKGSISDSEGRNIDFRNTIIIMTSN 728
Cdd:smart00382 83 ILDEITSLLDAEQEALLL---LLEELRLLLLLKSEKNLTVILTTN 124
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
222-370 |
1.77e-08 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 57.61 E-value: 1.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 222 ILVGDPGVGKTAIVEGLAQQIvdgnvppvlkNVELRSLDLSLLqAGASIkGEFENRLKDVINEIKQSEtPIIMFIDEAHT 301
Cdd:COG0464 195 LLYGPPGTGKTLLARALAGEL----------GLPLIEVDLSDL-VSKYV-GETEKNLREVFDKARGLA-PCVLFIDEADA 261
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 84377691 302 LIGAGGAAGQ---NDAANILKPALARGEFRSL--AATTWAEykqyfETDAALTRRFQ-VVAVGEPNETDAVHMLR 370
Cdd:COG0464 262 LAGKRGEVGDgvgRRVVNTLLTEMEELRSDVVviAATNRPD-----LLDPALLRRFDeIIFFPLPDAEERLEIFR 331
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
610-731 |
5.36e-08 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 52.29 E-value: 5.36e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 610 FLMCGPSGVGKTETALALTDLLYGgeRNVTTINMTEFKEEhkvSMLLGS--PAGYVGYGKGGVLTEAVRKNpySVLLLDE 687
Cdd:pfam07728 2 VLLVGPPGTGKTELAERLAAALSN--RPVFYVQLTRDTTE---EDLFGRrnIDPGGASWVDGPLVRAAREG--EIAVLDE 74
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 84377691 688 MEKAHPGVHDIFYQIFDKGSISDSEGRNID---FRNTIIIMTSNAAD 731
Cdd:pfam07728 75 INRANPDVLNSLLSLLDERRLLLPDGGELVkaaPDGFRLIATMNPLD 121
|
|
| ClpB_D2-small |
pfam10431 |
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, ... |
776-841 |
4.08e-07 |
|
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, referred to as the D2-small domain, and is a mixed alpha-beta structure. Compared with the D1-small domain (included in AAA, pfam00004) it lacks the long coiled-coil insertion, and instead of helix C4 contains a beta-strand (e3) that is part of a three stranded beta-pleated sheet. In Thermophilus the whole protein forms a hexamer with the D1-small and D2-small domains located on the outside of the hexamer, with the long coiled-coil being exposed on the surface. The D2-small domain is essential for oligomerization, forming a tight interface with the D2-large domain of a neighbouring subunit and thereby providing enough binding energy to stabilize the functional assembly. The domain is associated with two Clp_N, pfam02861, at the N-terminus as well as AAA, pfam00004 and AAA_2, pfam07724.
Pssm-ID: 463090 [Multi-domain] Cd Length: 81 Bit Score: 48.17 E-value: 4.08e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 84377691 776 LNDNEMAQIAKLSLRRIERRVREHySASFEYSLQVIELLVQLNQSPETGARAIEQLINRKLMPELA 841
Cdd:pfam10431 1 LSKEELRKIVDLQLKELQKRLAER-GITLELTDAAKDWLAEKGYDPEYGARPLRRAIQREIEDPLA 65
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
217-354 |
4.78e-07 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 50.06 E-value: 4.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 217 RQNSPILVGDPGVGKTAIVEGLAQQIVDGNVPPVLKNVE-----LRSLDLSLLQAGASIKGEFENRLKDVINEIKQSETP 291
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEdileeVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 84377691 292 IImFIDEAHTLIGAGGAAG--QNDAANILKPALARGEFRSLAATTWAEYKQYFETDAALTRRFQV 354
Cdd:smart00382 81 VL-ILDEITSLLDAEQEALllLLEELRLLLLLKSEKNLTVILTTNDEKDLGPALLRRRFDRRIVL 144
|
|
| ClpB_D2-small |
smart01086 |
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, ... |
776-842 |
1.91e-06 |
|
C-terminal, D2-small domain, of ClpB protein; This is the C-terminal domain of ClpB protein, referred to as the D2-small domain, and is a mixed alpha-beta structure. Compared with the D1-small domain (included in AAA) it lacks the long coiled-coil insertion, and instead of helix C4 contains a beta-strand (e3) that is part of a three stranded beta-pleated sheet. In Thermophilus the whole protein forms a hexamer with the D1-small and D2-small domains located on the outside of the hexamer, with the long coiled-coil being exposed on the surface. The D2-small domain is essential for oligomerisation, forming a tight interface with the D2-large domain of a neighbouring subunit and thereby providing enough binding energy to stabilise the functional assembly. The domain is associated with two Clp_N at the N-terminus as well as AAA and AAA_2.
Pssm-ID: 198154 [Multi-domain] Cd Length: 90 Bit Score: 46.67 E-value: 1.91e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 84377691 776 LNDNEMAQIAKLSLRRIERRVREHySASFEYSLQVIELLVQLNQSPETGARAIEQLINRKLMPELAN 842
Cdd:smart01086 1 LDKEDLVRIVDLPLNALQKRLAEK-GITLEFTDEALDWLAEKGYDPKYGARPLRRIIQRELEDPLAE 66
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
222-355 |
4.78e-06 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 47.28 E-value: 4.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 222 ILVGDPGVGKTAIVEGLAQQIvdgnvppvlkNVELRSLDLSLLQAGASikGEFENRLKDVINEIKQSeTPIIMFIDEAHT 301
Cdd:cd19481 30 LLYGPPGTGKTLLAKALAGEL----------GLPLIVVKLSSLLSKYV--GESEKNLRKIFERARRL-APCILFIDEIDA 96
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 84377691 302 LIGAGGAAGQNDAANILKPAL--------ARGEFRSLAATTWAEykqyfETDAALTR--RFQVV 355
Cdd:cd19481 97 IGRKRDSSGESGELRRVLNQLlteldgvnSRSKVLVIAATNRPD-----LLDPALLRpgRFDEV 155
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
201-300 |
9.38e-06 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 46.73 E-value: 9.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 201 GRGDEIRKSIDILCRRRQNSP---ILVGDPGVGKTAIVEGLAQQIVDGNVPPV-----------------LKNVELRSLD 260
Cdd:pfam13191 4 GREEELEQLLDALDRVRSGRPpsvLLTGEAGTGKTTLLRELLRALERDGGYFLrgkcdenlpyspllealTREGLLRQLL 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 84377691 261 ---------------LSLLQAGASIKGEFENRLKDVINEI----KQSETPIIMFIDEAH 300
Cdd:pfam13191 84 delesslleawraalLEALAPVPELPGDLAERLLDLLLRLldllARGERPLVLVLDDLQ 142
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
222-298 |
6.55e-04 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 41.12 E-value: 6.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 222 ILVGDPGVGKTAIVEGLAQQIvdgnvppvlkNVELRSLDlsllqaGASIK----GEFENRLKDVINEiKQSETPIIMFID 297
Cdd:cd19503 38 LLHGPPGTGKTLLARAVANEA----------GANFLSIS------GPSIVskylGESEKNLREIFEE-ARSHAPSIIFID 100
|
.
gi 84377691 298 E 298
Cdd:cd19503 101 E 101
|
|
| ExeA |
COG3267 |
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ... |
223-302 |
1.48e-03 |
|
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 442498 [Multi-domain] Cd Length: 261 Bit Score: 41.31 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 223 LVGDPGVGKTAIVEGLAQQIVDGNVP-----PVLKNVEL-RSL--DLSLLQAGASiKGEFENRLKDVINEIKQSETPIIM 294
Cdd:COG3267 48 LTGEVGTGKTTLLRRLLERLPDDVKVayipnPQLSPAELlRAIadELGLEPKGAS-KADLLRQLQEFLLELAAAGRRVVL 126
|
....*...
gi 84377691 295 FIDEAHTL 302
Cdd:COG3267 127 IIDEAQNL 134
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
222-352 |
1.96e-03 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 39.20 E-value: 1.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 222 ILVGDPGVGKTAIVEGLAQQIVDGNVPPVL----------------KNVELRSLDLSLLQAGAS----IKGEFENRLKDV 281
Cdd:pfam07728 3 LLVGPPGTGKTELAERLAAALSNRPVFYVQltrdtteedlfgrrniDPGGASWVDGPLVRAAREgeiaVLDEINRANPDV 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 84377691 282 INEikqsetpIIMFIDEAHTLIGAGGaagqndaanilKPALARGEFRSLAATTWAEYKQYFETDAALTRRF 352
Cdd:pfam07728 83 LNS-------LLSLLDERRLLLPDGG-----------ELVKAAPDGFRLIATMNPLDRGLNELSPALRSRF 135
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
222-370 |
2.05e-03 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 41.15 E-value: 2.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 222 ILVGDPGVGKTAIVEGLAQQIvdgnvppvlkNVELRSLDLS-LLQagaSIKGEFENRLKDVINEIKqSETPIIMFIDEAH 300
Cdd:COG1222 116 LLYGPPGTGKTLLAKAVAGEL----------GAPFIRVRGSeLVS---KYIGEGARNVREVFELAR-EKAPSIIFIDEID 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 301 TLIGAGGAAGQNDAANILKPAL--------ARGEFRSLAATtwaeykQYFET-DAALTR--RF-QVVAVGEPNETDAVHM 368
Cdd:COG1222 182 AIAARRTDDGTSGEVQRTVNQLlaeldgfeSRGDVLIIAAT------NRPDLlDPALLRpgRFdRVIEVPLPDEEAREEI 255
|
..
gi 84377691 369 LR 370
Cdd:COG1222 256 LK 257
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
586-691 |
2.50e-03 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 39.57 E-value: 2.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 586 IAEISQAIRMSRAGLTDPRKPVGVFLMCGPSGVGKTETALALtdllyGGERNVTTINM--TEFKEEHK--VSMLLGSpag 661
Cdd:cd19481 5 LREAVEAPRRGSRLRRYGLGLPKGILLYGPPGTGKTLLAKAL-----AGELGLPLIVVklSSLLSKYVgeSEKNLRK--- 76
|
90 100 110
....*....|....*....|....*....|
gi 84377691 662 yvgygkggvLTEAVRKNPYSVLLLDEMEKA 691
Cdd:cd19481 77 ---------IFERARRLAPCILFIDEIDAI 97
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
430-503 |
5.31e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.52 E-value: 5.31e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 84377691 430 QLEAIEEKIQYTRNEIDTLLHESALWSIEDERLGLAQEaLLELEQNRKDLADRWEQEKSSVELIIELQTELDSL 503
Cdd:COG4717 96 ELEELEEELEELEAELEELREELEKLEKLLQLLPLYQE-LEALEAELAELPERLEELEERLEELRELEEELEEL 168
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
579-689 |
6.49e-03 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 39.60 E-value: 6.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84377691 579 VIGQTTPIAEISQAI--------RMSRAGLTDPRKpvgvFLMCGPSGVGKTETALALtdllyGGERNVTTINMT--EFke 648
Cdd:COG1222 80 IGGLDEQIEEIREAVelplknpeLFRKYGIEPPKG----VLLYGPPGTGKTLLAKAV-----AGELGAPFIRVRgsEL-- 148
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 84377691 649 ehkVSMLLGSPAgyvgyGKGGVLTEAVRKNPYSVLLLDEME 689
Cdd:COG1222 149 ---VSKYIGEGA-----RNVREVFELAREKAPSIIFIDEID 181
|
|
| HprK_C |
cd01918 |
HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the ... |
607-627 |
8.78e-03 |
|
HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent phosphorylation of Ser-46 of HPr and its dephosphorylation by phosphorolysis. The latter reaction uses inorganic phosphate as substrate and produces pyrophosphate. Phosphoenolpyruvate carboxykinase (PEPCK) and the C-terminal catalytic domain of HprK/P are structurally similar with conserved active site residues suggesting these two phosphotransferases have related functions. The HprK/P N-terminal domain is structurally similar to the N-terminal domains of the MurE and MurF amino acid ligases.
Pssm-ID: 238899 Cd Length: 149 Bit Score: 37.60 E-value: 8.78e-03
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| HprK |
COG1493 |
Serine kinase of the HPr protein, regulates carbohydrate metabolism [Signal transduction ... |
607-627 |
9.33e-03 |
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Serine kinase of the HPr protein, regulates carbohydrate metabolism [Signal transduction mechanisms];
Pssm-ID: 441102 [Multi-domain] Cd Length: 142 Bit Score: 37.47 E-value: 9.33e-03
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