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Conserved domains on  [gi|84379819|gb|EAP96670|]
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putative acriflavin resistence protein [Vibrio splendidus 12B01]

Protein Classification

efflux RND transporter permease subunit( domain architecture ID 11436314)

efflux RND transporter permease subunit similar to Bacillus subtilis swarming motility protein SwrC, which is required for self-resistance to surfactin, an antimicrobial lipopeptide surfactant produced by B. subtilis

PubMed:  19026770|10941792
TCDB:  2.A.6

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
AcrB COG0841
Multidrug efflux pump subunit AcrB [Defense mechanisms];
1-1036 0e+00

Multidrug efflux pump subunit AcrB [Defense mechanisms];


:

Pssm-ID: 440603 [Multi-domain]  Cd Length: 1015  Bit Score: 1151.00  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    1 MLSRFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMS 80
Cdd:COG0841    2 NLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYIT 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   81 SKSaNDGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPDLLMVLNFYSPNgeYDDQFLINYVN 160
Cdd:COG0841   82 STS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYAE 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  161 LNIKDQLARVSGISEVNVLGGGEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIGAapyanpQEVQFNLVTKG 240
Cdd:COG0841  159 RNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGG------GDREYTVRTNG 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  241 RLETADEFENVVLRANqDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTNFP 320
Cdd:COG0841  233 RLKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLP 311
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  321 EGVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGL 400
Cdd:COG0841  312 EGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFAL 391
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  401 ILAIGIVVDDAILVIENVDTTMAKDptISPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTICIA 480
Cdd:COG0841  392 VLAIGIVVDDAIVVVENIERHMEEG--LSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIA 469
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  481 VVISSINALTLSPALCSLVLKQGGGNT-ARWYQAFNRGLESVTNKYGQIAGFLVKKGVLLFTFFVVALAAVTYFAKTTST 559
Cdd:COG0841  470 LLISLFVALTLTPALCARLLKPHPKGKkGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPT 549
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  560 AFVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLEMVEQEPGVDGVTLVNGYAFmtGASASNGASLFIKLHDWDMRNald 639
Cdd:COG0841  550 EFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSG--GGSGSNSGTIFVTLKPWDERD--- 624
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  640 gqHSAQAISQRINGRAAtELPQAIVFAMGPPAvPGMGAASGFEFVLEdtlGRSRTDLAMVMNDVIAEANKQPEISHTFST 719
Cdd:COG0841  625 --RSADEIIARLREKLA-KIPGARVFVFQPPA-GGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPGLVDVRSD 697
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  720 FRANVPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQRFHVRSSNGEMI 799
Cdd:COG0841  698 LQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMV 777
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  800 PLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAE-VLPQGYQYEWTGMAYQEVLAGNQAIFAF 878
Cdd:COG0841  778 PLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElKLPPGVSIEFTGQAEEEQESFSSLGLAF 857
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  879 ALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEFAKVEREEKd 958
Cdd:COG0841  858 LLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEG- 936
                        970       980       990      1000      1010      1020      1030
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 84379819  959 ASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAFVQRKREK 1036
Cdd:COG0841  937 MSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLRRR 1014
 
Name Accession Description Interval E-value
AcrB COG0841
Multidrug efflux pump subunit AcrB [Defense mechanisms];
1-1036 0e+00

Multidrug efflux pump subunit AcrB [Defense mechanisms];


Pssm-ID: 440603 [Multi-domain]  Cd Length: 1015  Bit Score: 1151.00  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    1 MLSRFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMS 80
Cdd:COG0841    2 NLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYIT 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   81 SKSaNDGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPDLLMVLNFYSPNgeYDDQFLINYVN 160
Cdd:COG0841   82 STS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYAE 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  161 LNIKDQLARVSGISEVNVLGGGEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIGAapyanpQEVQFNLVTKG 240
Cdd:COG0841  159 RNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGG------GDREYTVRTNG 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  241 RLETADEFENVVLRANqDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTNFP 320
Cdd:COG0841  233 RLKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLP 311
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  321 EGVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGL 400
Cdd:COG0841  312 EGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFAL 391
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  401 ILAIGIVVDDAILVIENVDTTMAKDptISPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTICIA 480
Cdd:COG0841  392 VLAIGIVVDDAIVVVENIERHMEEG--LSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIA 469
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  481 VVISSINALTLSPALCSLVLKQGGGNT-ARWYQAFNRGLESVTNKYGQIAGFLVKKGVLLFTFFVVALAAVTYFAKTTST 559
Cdd:COG0841  470 LLISLFVALTLTPALCARLLKPHPKGKkGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPT 549
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  560 AFVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLEMVEQEPGVDGVTLVNGYAFmtGASASNGASLFIKLHDWDMRNald 639
Cdd:COG0841  550 EFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSG--GGSGSNSGTIFVTLKPWDERD--- 624
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  640 gqHSAQAISQRINGRAAtELPQAIVFAMGPPAvPGMGAASGFEFVLEdtlGRSRTDLAMVMNDVIAEANKQPEISHTFST 719
Cdd:COG0841  625 --RSADEIIARLREKLA-KIPGARVFVFQPPA-GGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPGLVDVRSD 697
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  720 FRANVPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQRFHVRSSNGEMI 799
Cdd:COG0841  698 LQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMV 777
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  800 PLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAE-VLPQGYQYEWTGMAYQEVLAGNQAIFAF 878
Cdd:COG0841  778 PLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElKLPPGVSIEFTGQAEEEQESFSSLGLAF 857
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  879 ALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEFAKVEREEKd 958
Cdd:COG0841  858 LLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEG- 936
                        970       980       990      1000      1010      1020      1030
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 84379819  959 ASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAFVQRKREK 1036
Cdd:COG0841  937 MSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLRRR 1014
2A0602 TIGR00915
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ...
2-1032 0e+00

The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 273335 [Multi-domain]  Cd Length: 1044  Bit Score: 1033.14  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819      2 LSRFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMSS 81
Cdd:TIGR00915    1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819     82 KSANDGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPDLLMVLNFYSPNGEYDDQFLINYVNL 161
Cdd:TIGR00915   81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    162 NIKDQLARVSGISEVNVLGGgEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIGAAPYANPQEVQFNLVTKGR 241
Cdd:TIGR00915  161 NMVDPLSRLEGVGDVQLFGS-QYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTR 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    242 LETADEFENVVLRANQDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTNFPE 321
Cdd:TIGR00915  240 LQTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQ 319
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    322 GVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLI 401
Cdd:TIGR00915  320 GMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMV 399
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    402 LAIGIVVDDAILVIENVDTTMAkDPTISPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTICIAV 481
Cdd:TIGR00915  400 LAIGLLVDDAIVVVENVERVMA-EEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAM 478
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    482 VISSINALTLSPALCSLVLKQG-----GGNTARWYQAFNRGLESVTNKYGQIAGFLVKKGVLLFTFFVVALAAVTYFAKT 556
Cdd:TIGR00915  479 ALSVLVALILTPALCATMLKPIekgehHEKKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVR 558
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    557 TSTAFVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLE--MVEQEPGVDGVTLVNGYAFmtGASASNGASLFIKLHDWDM 634
Cdd:TIGR00915  559 LPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKylLAKEKANVESVFTVNGFSF--AGRGQNMGMAFIRLKDWEE 636
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    635 RNAldGQHSAQAISQRINGRAATeLPQAIVFAMGPPAVPGMGAASGFEFVLEDTLGRSRTDLAMVMNDVIAEANKQPEIS 714
Cdd:TIGR00915  637 RTG--KENSVFAIAGRATGHFMQ-IKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPALT 713
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    715 HTFSTFRANVPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQRFHVRSS 794
Cdd:TIGR00915  714 RVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNA 793
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    795 NGEMIPLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAEvLPQGYQYEWTGMAYQEVLAGNQA 874
Cdd:TIGR00915  794 SGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQK-LPPGFGFSWTGMSYEERLSGSQA 872
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    875 IFAFALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEFAKvER 954
Cdd:TIGR00915  873 PALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAK-EL 951
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 84379819    955 EEKDASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAFVQR 1032
Cdd:TIGR00915  952 MAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRR 1029
ACR_tran pfam00873
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ...
2-1030 0e+00

AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.


Pssm-ID: 395701 [Multi-domain]  Cd Length: 1021  Bit Score: 988.72  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819      2 LSRFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMSS 81
Cdd:pfam00873    1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819     82 KSaNDGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPDLLMVLNFYSPNGEYDDQFLINYVNL 161
Cdd:pfam00873   81 QS-SYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    162 NIKDQLARVSGISEVNVLGGGEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIgaapyANPQEvQFNLVTKGR 241
Cdd:pfam00873  160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL-----EGQGL-QALIRAQGQ 233
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    242 LETADEFENVVLRaNQDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTNFPE 321
Cdd:pfam00873  234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    322 GVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLI 401
Cdd:pfam00873  313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    402 LAIGIVVDDAILVIENVDTTMAKDPTiSPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTICIAV 481
Cdd:pfam00873  393 LAIGLVVDDAIVVVENIERVLEENGL-KPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAI 471
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    482 VISSINALTLSPALCSLVLKQG-GGNTARWYQAFNRGLESVTNKYGQIAGFLVKKGVLLFTFFVVALAAVTYFAKTTSTA 560
Cdd:pfam00873  472 LLSVLVALTLTPALCATLLKPRrEPKHGGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTE 551
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    561 FVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLEMVEQEPGVDGVTLVNGYAFMTGASASNGASLFIKLHDWDMRNALDG 640
Cdd:pfam00873  552 FLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFSGDNNGPNSGDAFISLKPWKERPGPEK 631
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    641 qhSAQAISQRINgRAATELPQAIVFAMGPPAVPGMGAASGFEFVLEDTL-GRSRTDLAMVMNDVIAEANKQPEISHTFST 719
Cdd:pfam00873  632 --SVQALIERLR-KALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIfGDDLDALDEARNQILAALAQLPGLSDVRSD 708
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    720 FRANVPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQRFHVRSSNGEMI 799
Cdd:pfam00873  709 GQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMI 788
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    800 PLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAEV-LPQGYQYEWTGMAYQEVLAGNQAIFAF 878
Cdd:pfam00873  789 PLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVkLPPGYGYTWTGQFEQEQLAGNSLPILI 868
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    879 ALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEFAKVEREEKD 958
Cdd:pfam00873  869 ALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQEG 948
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 84379819    959 ASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAFV 1030
Cdd:pfam00873  949 KSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLF 1020
PRK15127 PRK15127
multidrug efflux RND transporter permease subunit AcrB;
2-1036 0e+00

multidrug efflux RND transporter permease subunit AcrB;


Pssm-ID: 185081 [Multi-domain]  Cd Length: 1049  Bit Score: 839.18  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819     2 LSRFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMSS 81
Cdd:PRK15127    1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    82 KSANDGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPDLLMVLNFYSPNGEYDDQFLINYVNL 161
Cdd:PRK15127   81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   162 NIKDQLARVSGISEVNVLGGgEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIGAAPYANPQEVQFNLVTKGR 241
Cdd:PRK15127  161 NMKDPISRTSGVGDVQLFGS-QYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTR 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   242 LETADEFENVVLRANQDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTNFPE 321
Cdd:PRK15127  240 LTSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   322 GVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLI 401
Cdd:PRK15127  320 GLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMV 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   402 LAIGIVVDDAILVIENVDTTMAKDpTISPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTICIAV 481
Cdd:PRK15127  400 LAIGLLVDDAIVVVENVERVMAEE-GLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAM 478
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   482 VISSINALTLSPALCSLVLK-----QGGGNTARWYQAFNRGLESVTNKY-GQIAGFLVKKGVLLFTFFVVALAAVTYFAK 555
Cdd:PRK15127  479 ALSVLVALILTPALCATMLKpiakgDHGEGKKGFFGWFNRMFEKSTHHYtDSVGNILRSTGRYLVLYLIIVVGMAYLFVR 558
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   556 TTSTaFVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLE--MVEQEPGVDGVTLVNGYAFmTGASASNGASlFIKLHDWD 633
Cdd:PRK15127  559 LPSS-FLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDyyLTKEKNNVESVFAVNGFGF-AGRGQNTGIA-FVSLKDWA 635
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   634 MRNAldGQHSAQAISQRINGrAATELPQAIVFAMGPPAVPGMGAASGFEFVLEDTLGRSRTDLAMVMNDVIAEANKQPEi 713
Cdd:PRK15127  636 DRPG--EENKVEAITMRATR-AFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPD- 711
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   714 shTFSTFRAN----VPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQRF 789
Cdd:PRK15127  712 --MLVGVRPNgledTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDW 789
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   790 HVRSSNGEMIPLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAEvLPQGYQYEWTGMAYQEVL 869
Cdd:PRK15127  790 YVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASK-LPTGVGYDWTGMSYQERL 868
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   870 AGNQAIFAFALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEF 949
Cdd:PRK15127  869 SGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEF 948
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   950 AKVEREEKDASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAF 1029
Cdd:PRK15127  949 AKDLMDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVV 1028

                  ....*..
gi 84379819  1030 VQRKREK 1036
Cdd:PRK15127 1029 VRRRFSR 1035
RND_permease_2 NF033617
multidrug efflux RND transporter permease subunit;
3-1032 0e+00

multidrug efflux RND transporter permease subunit;


Pssm-ID: 411236 [Multi-domain]  Cd Length: 1009  Bit Score: 759.17  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819     3 SRFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMSSK 82
Cdd:NF033617    1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    83 SANdGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPDL-LMVLNFYS---PNGEYDDqflinY 158
Cdd:NF033617   81 SSL-GYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTpIMYIGLTSeemPRGQLTD-----Y 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   159 VNLNIKDQLARVSGISEVNVLGGGEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRigaapyANPQEVQFNLVT 238
Cdd:NF033617  155 AERVLAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGA------VRGDSVVSTVRA 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   239 KGRLETADEFENVVLRANQDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTN 318
Cdd:NF033617  229 NDQLKTAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQET 308
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   319 FPEGVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLF 398
Cdd:NF033617  309 LPKNIKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLM 388
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   399 GLILAIGIVVDDAILVIENVDTTMAKDPtiSPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTIC 478
Cdd:NF033617  389 ALVLAIGLVVDDAIVVVENIHRHIEEGE--SPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLA 466
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   479 IAVVISSINALTLSPALCSLVLKQGGgNTARWYQAFNRGLESVTNKYGQIAGFLVK--KGVLLFTFFVVALAAVTYfaKT 556
Cdd:NF033617  467 GAVIISGIVALTLTPMMCSRLLKANE-KPGRFARAVDRFFDGLTARYGRGLKWVLKhrPLTLVVALATLALLPLLY--VF 543
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   557 TSTAFVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLEMVEQEPGVDGVTLVNGYAfmtGASASNGASLFIKLHDWDMRN 636
Cdd:NF033617  544 IPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVG---GNPGDNTGFGIINLKPWDERD 620
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   637 AldgqhSAQAISQRINGRAAtELPQAIVFAMGPPAVPGmGAASGFEFVLEDTLGRSRTDLAMVMNDVIAEANKQPEISHT 716
Cdd:NF033617  621 V-----SAQEIIDRLRPKLA-KVPGMDLFLFPLQDLPG-GAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADV 693
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   717 FSTFRANVPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQRFHVRSSNG 796
Cdd:NF033617  694 DSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDG 773
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   797 EMIPLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAEVLPQGYQYEWTGMAYQEVLAGNQAIF 876
Cdd:NF033617  774 KLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKELLPSGISGSFQGAARAFQEEGSSLLF 853
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   877 AFALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEFAKVEREE 956
Cdd:NF033617  854 LFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRH 933
                         970       980       990      1000      1010      1020      1030
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 84379819   957 KDASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAFVQR 1032
Cdd:NF033617  934 QGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
 
Name Accession Description Interval E-value
AcrB COG0841
Multidrug efflux pump subunit AcrB [Defense mechanisms];
1-1036 0e+00

Multidrug efflux pump subunit AcrB [Defense mechanisms];


Pssm-ID: 440603 [Multi-domain]  Cd Length: 1015  Bit Score: 1151.00  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    1 MLSRFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMS 80
Cdd:COG0841    2 NLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYIT 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   81 SKSaNDGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPDLLMVLNFYSPNgeYDDQFLINYVN 160
Cdd:COG0841   82 STS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYAE 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  161 LNIKDQLARVSGISEVNVLGGGEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIGAapyanpQEVQFNLVTKG 240
Cdd:COG0841  159 RNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGG------GDREYTVRTNG 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  241 RLETADEFENVVLRANqDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTNFP 320
Cdd:COG0841  233 RLKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLP 311
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  321 EGVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGL 400
Cdd:COG0841  312 EGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFAL 391
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  401 ILAIGIVVDDAILVIENVDTTMAKDptISPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTICIA 480
Cdd:COG0841  392 VLAIGIVVDDAIVVVENIERHMEEG--LSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIA 469
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  481 VVISSINALTLSPALCSLVLKQGGGNT-ARWYQAFNRGLESVTNKYGQIAGFLVKKGVLLFTFFVVALAAVTYFAKTTST 559
Cdd:COG0841  470 LLISLFVALTLTPALCARLLKPHPKGKkGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPT 549
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  560 AFVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLEMVEQEPGVDGVTLVNGYAFmtGASASNGASLFIKLHDWDMRNald 639
Cdd:COG0841  550 EFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSG--GGSGSNSGTIFVTLKPWDERD--- 624
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  640 gqHSAQAISQRINGRAAtELPQAIVFAMGPPAvPGMGAASGFEFVLEdtlGRSRTDLAMVMNDVIAEANKQPEISHTFST 719
Cdd:COG0841  625 --RSADEIIARLREKLA-KIPGARVFVFQPPA-GGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPGLVDVRSD 697
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  720 FRANVPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQRFHVRSSNGEMI 799
Cdd:COG0841  698 LQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMV 777
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  800 PLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAE-VLPQGYQYEWTGMAYQEVLAGNQAIFAF 878
Cdd:COG0841  778 PLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElKLPPGVSIEFTGQAEEEQESFSSLGLAF 857
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  879 ALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEFAKVEREEKd 958
Cdd:COG0841  858 LLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEG- 936
                        970       980       990      1000      1010      1020      1030
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 84379819  959 ASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAFVQRKREK 1036
Cdd:COG0841  937 MSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLRRR 1014
2A0602 TIGR00915
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ...
2-1032 0e+00

The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 273335 [Multi-domain]  Cd Length: 1044  Bit Score: 1033.14  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819      2 LSRFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMSS 81
Cdd:TIGR00915    1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819     82 KSANDGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPDLLMVLNFYSPNGEYDDQFLINYVNL 161
Cdd:TIGR00915   81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    162 NIKDQLARVSGISEVNVLGGgEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIGAAPYANPQEVQFNLVTKGR 241
Cdd:TIGR00915  161 NMVDPLSRLEGVGDVQLFGS-QYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTR 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    242 LETADEFENVVLRANQDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTNFPE 321
Cdd:TIGR00915  240 LQTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQ 319
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    322 GVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLI 401
Cdd:TIGR00915  320 GMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMV 399
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    402 LAIGIVVDDAILVIENVDTTMAkDPTISPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTICIAV 481
Cdd:TIGR00915  400 LAIGLLVDDAIVVVENVERVMA-EEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAM 478
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    482 VISSINALTLSPALCSLVLKQG-----GGNTARWYQAFNRGLESVTNKYGQIAGFLVKKGVLLFTFFVVALAAVTYFAKT 556
Cdd:TIGR00915  479 ALSVLVALILTPALCATMLKPIekgehHEKKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVR 558
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    557 TSTAFVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLE--MVEQEPGVDGVTLVNGYAFmtGASASNGASLFIKLHDWDM 634
Cdd:TIGR00915  559 LPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKylLAKEKANVESVFTVNGFSF--AGRGQNMGMAFIRLKDWEE 636
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    635 RNAldGQHSAQAISQRINGRAATeLPQAIVFAMGPPAVPGMGAASGFEFVLEDTLGRSRTDLAMVMNDVIAEANKQPEIS 714
Cdd:TIGR00915  637 RTG--KENSVFAIAGRATGHFMQ-IKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPALT 713
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    715 HTFSTFRANVPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQRFHVRSS 794
Cdd:TIGR00915  714 RVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNA 793
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    795 NGEMIPLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAEvLPQGYQYEWTGMAYQEVLAGNQA 874
Cdd:TIGR00915  794 SGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQK-LPPGFGFSWTGMSYEERLSGSQA 872
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    875 IFAFALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEFAKvER 954
Cdd:TIGR00915  873 PALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAK-EL 951
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 84379819    955 EEKDASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAFVQR 1032
Cdd:TIGR00915  952 MAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRR 1029
ACR_tran pfam00873
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ...
2-1030 0e+00

AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.


Pssm-ID: 395701 [Multi-domain]  Cd Length: 1021  Bit Score: 988.72  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819      2 LSRFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMSS 81
Cdd:pfam00873    1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819     82 KSaNDGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPDLLMVLNFYSPNGEYDDQFLINYVNL 161
Cdd:pfam00873   81 QS-SYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    162 NIKDQLARVSGISEVNVLGGGEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIgaapyANPQEvQFNLVTKGR 241
Cdd:pfam00873  160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL-----EGQGL-QALIRAQGQ 233
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    242 LETADEFENVVLRaNQDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTNFPE 321
Cdd:pfam00873  234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    322 GVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLI 401
Cdd:pfam00873  313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    402 LAIGIVVDDAILVIENVDTTMAKDPTiSPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTICIAV 481
Cdd:pfam00873  393 LAIGLVVDDAIVVVENIERVLEENGL-KPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAI 471
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    482 VISSINALTLSPALCSLVLKQG-GGNTARWYQAFNRGLESVTNKYGQIAGFLVKKGVLLFTFFVVALAAVTYFAKTTSTA 560
Cdd:pfam00873  472 LLSVLVALTLTPALCATLLKPRrEPKHGGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTE 551
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    561 FVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLEMVEQEPGVDGVTLVNGYAFMTGASASNGASLFIKLHDWDMRNALDG 640
Cdd:pfam00873  552 FLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFSGDNNGPNSGDAFISLKPWKERPGPEK 631
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    641 qhSAQAISQRINgRAATELPQAIVFAMGPPAVPGMGAASGFEFVLEDTL-GRSRTDLAMVMNDVIAEANKQPEISHTFST 719
Cdd:pfam00873  632 --SVQALIERLR-KALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIfGDDLDALDEARNQILAALAQLPGLSDVRSD 708
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    720 FRANVPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQRFHVRSSNGEMI 799
Cdd:pfam00873  709 GQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMI 788
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    800 PLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAEV-LPQGYQYEWTGMAYQEVLAGNQAIFAF 878
Cdd:pfam00873  789 PLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVkLPPGYGYTWTGQFEQEQLAGNSLPILI 868
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    879 ALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEFAKVEREEKD 958
Cdd:pfam00873  869 ALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQEG 948
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 84379819    959 ASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAFV 1030
Cdd:pfam00873  949 KSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLF 1020
PRK15127 PRK15127
multidrug efflux RND transporter permease subunit AcrB;
2-1036 0e+00

multidrug efflux RND transporter permease subunit AcrB;


Pssm-ID: 185081 [Multi-domain]  Cd Length: 1049  Bit Score: 839.18  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819     2 LSRFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMSS 81
Cdd:PRK15127    1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    82 KSANDGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPDLLMVLNFYSPNGEYDDQFLINYVNL 161
Cdd:PRK15127   81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   162 NIKDQLARVSGISEVNVLGGgEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIGAAPYANPQEVQFNLVTKGR 241
Cdd:PRK15127  161 NMKDPISRTSGVGDVQLFGS-QYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTR 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   242 LETADEFENVVLRANQDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTNFPE 321
Cdd:PRK15127  240 LTSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   322 GVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLI 401
Cdd:PRK15127  320 GLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMV 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   402 LAIGIVVDDAILVIENVDTTMAKDpTISPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTICIAV 481
Cdd:PRK15127  400 LAIGLLVDDAIVVVENVERVMAEE-GLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAM 478
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   482 VISSINALTLSPALCSLVLK-----QGGGNTARWYQAFNRGLESVTNKY-GQIAGFLVKKGVLLFTFFVVALAAVTYFAK 555
Cdd:PRK15127  479 ALSVLVALILTPALCATMLKpiakgDHGEGKKGFFGWFNRMFEKSTHHYtDSVGNILRSTGRYLVLYLIIVVGMAYLFVR 558
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   556 TTSTaFVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLE--MVEQEPGVDGVTLVNGYAFmTGASASNGASlFIKLHDWD 633
Cdd:PRK15127  559 LPSS-FLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDyyLTKEKNNVESVFAVNGFGF-AGRGQNTGIA-FVSLKDWA 635
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   634 MRNAldGQHSAQAISQRINGrAATELPQAIVFAMGPPAVPGMGAASGFEFVLEDTLGRSRTDLAMVMNDVIAEANKQPEi 713
Cdd:PRK15127  636 DRPG--EENKVEAITMRATR-AFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPD- 711
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   714 shTFSTFRAN----VPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQRF 789
Cdd:PRK15127  712 --MLVGVRPNgledTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDW 789
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   790 HVRSSNGEMIPLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAEvLPQGYQYEWTGMAYQEVL 869
Cdd:PRK15127  790 YVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASK-LPTGVGYDWTGMSYQERL 868
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   870 AGNQAIFAFALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEF 949
Cdd:PRK15127  869 SGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEF 948
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   950 AKVEREEKDASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAF 1029
Cdd:PRK15127  949 AKDLMDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVV 1028

                  ....*..
gi 84379819  1030 VQRKREK 1036
Cdd:PRK15127 1029 VRRRFSR 1035
PRK09577 PRK09577
multidrug efflux RND transporter permease subunit;
2-1032 0e+00

multidrug efflux RND transporter permease subunit;


Pssm-ID: 169981 [Multi-domain]  Cd Length: 1032  Bit Score: 817.17  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819     2 LSRFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMSS 81
Cdd:PRK09577    1 MARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    82 KSANdGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPDLLMVLNFYSPNGEYDDQFLINYVNL 161
Cdd:PRK09577   81 TSSA-GQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASA 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   162 NIKDQLARVSGISEVNVLGGgEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIGAAPYANPQEVQFNLVTKGR 241
Cdd:PRK09577  160 NVLQALRRVEGVGKVQFWGA-EYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAP 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   242 LETADEFENVVLRANQDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTNFPE 321
Cdd:PRK09577  239 LKTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPP 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   322 GVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLI 401
Cdd:PRK09577  319 GVKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMV 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   402 LAIGIVVDDAILVIENVDTTMAKDpTISPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTICIAV 481
Cdd:PRK09577  399 LAIGILVDDAIVVVENVERLMVEE-GLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSI 477
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   482 VISSINALTLSPALCSLVLK---QGGGNTARWYQAFNRGLESVTNKYGQIAGFLVKKGVLLFTFFVVALAAVTYFAKTTS 558
Cdd:PRK09577  478 GFSAFLALSLTPALCATLLKpvdGDHHEKRGFFGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLP 557
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   559 TAFVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLEMVEQEPGVDGVTLVNGYAFMtgASASNGASLFIKLHDWDMRNAL 638
Cdd:PRK09577  558 TAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLY--GEGPNGGMIFVTLKDWKERKAA 635
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   639 DgQHsAQAISQRINGRAATeLPQAIVFAMGPPAVPGMGAASGFEFVLEDTLGRSRTDLAMVMNDVIAEANKQPEISHTFS 718
Cdd:PRK09577  636 R-DH-VQAIVARINERFAG-TPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDPALTDLMF 712
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   719 TFRANVPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFtMFGKNFR-VTMQADSEHRSSMDDLQRFHVRSSNGE 797
Cdd:PRK09577  713 AGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDF-MHGSQVRrVIVQADGRHRLDPDDVKKLRVRNAQGE 791
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   798 MIPLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAEvLPQGYQYEWTGMAYQEVLAGNQAIFA 877
Cdd:PRK09577  792 MVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAAT-LPAGIGYAWSGQSFEERLSGAQAPML 870
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   878 FALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEFAKvEREEK 957
Cdd:PRK09577  871 FALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAK-DLVAQ 949
                         970       980       990      1000      1010      1020      1030
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 84379819   958 DASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAFVQR 1032
Cdd:PRK09577  950 RMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVVGR 1024
PRK10555 PRK10555
multidrug efflux RND transporter permease AcrD;
2-1033 0e+00

multidrug efflux RND transporter permease AcrD;


Pssm-ID: 182544 [Multi-domain]  Cd Length: 1037  Bit Score: 815.22  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819     2 LSRFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMSS 81
Cdd:PRK10555    1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    82 KSANDGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPDLLMVLNFYSPNGEYDDQFLINYVNL 161
Cdd:PRK10555   81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   162 NIKDQLARVSGISEVNVLGGgEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIGAAPYANPQEVQFNLVTKGR 241
Cdd:PRK10555  161 NIQDPLSRVNGVGDIDAYGS-QYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSL 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   242 LETADEFENVVLRANQDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTNFPE 321
Cdd:PRK10555  240 LQTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPH 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   322 GVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLI 401
Cdd:PRK10555  320 GLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMV 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   402 LAIGIVVDDAILVIENVDTTMAKDpTISPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTICIAV 481
Cdd:PRK10555  400 LAIGLLVDDAIVVVENVERIMSEE-GLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAM 478
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   482 VISSINALTLSPALCSLVLK---QGGGNTAR-WYQAFNRGLESVTNKYGQIAGFLVKKGVLLFTFFVVALAAVTYFAKTT 557
Cdd:PRK10555  479 VLSVLVAMILTPALCATLLKplkKGEHHGQKgFFGWFNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRL 558
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   558 STAFVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLE--MVEQEPGVDGVTLVNGYAfmTGASASNGASLFIKLHDWDMR 635
Cdd:PRK10555  559 PTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKyyFTHEKDNVMSVFATVGSG--PGGNGQNVARMFIRLKDWDER 636
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   636 NALDGqhSAQAISQRInGRAATELPQAIVFAMGPPAVPGMGAASGFEFVLEDTLGRSRTDLAMVMNDVIAEANKQPEISH 715
Cdd:PRK10555  637 DSKTG--TSFAIIERA-TKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAKNPELTR 713
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   716 TFSTFRANVPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQRFHVRSSN 795
Cdd:PRK10555  714 VRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKD 793
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   796 GEMIPLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAEvLPQGYQYEWTGMAYQEVLAGNQAI 875
Cdd:PRK10555  794 GGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQ-LPNGFGLEWTAMSYQERLSGAQAP 872
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   876 FAFALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEFAKvERE 955
Cdd:PRK10555  873 ALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFAN-EMN 951
                         970       980       990      1000      1010      1020      1030
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 84379819   956 EKDASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAFVQRK 1033
Cdd:PRK10555  952 QKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFVPLFFVLVRRR 1029
RND_permease_2 NF033617
multidrug efflux RND transporter permease subunit;
3-1032 0e+00

multidrug efflux RND transporter permease subunit;


Pssm-ID: 411236 [Multi-domain]  Cd Length: 1009  Bit Score: 759.17  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819     3 SRFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMSSK 82
Cdd:NF033617    1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    83 SANdGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPDL-LMVLNFYS---PNGEYDDqflinY 158
Cdd:NF033617   81 SSL-GYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTpIMYIGLTSeemPRGQLTD-----Y 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   159 VNLNIKDQLARVSGISEVNVLGGGEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRigaapyANPQEVQFNLVT 238
Cdd:NF033617  155 AERVLAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGA------VRGDSVVSTVRA 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   239 KGRLETADEFENVVLRANQDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTN 318
Cdd:NF033617  229 NDQLKTAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQET 308
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   319 FPEGVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLF 398
Cdd:NF033617  309 LPKNIKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLM 388
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   399 GLILAIGIVVDDAILVIENVDTTMAKDPtiSPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTIC 478
Cdd:NF033617  389 ALVLAIGLVVDDAIVVVENIHRHIEEGE--SPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLA 466
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   479 IAVVISSINALTLSPALCSLVLKQGGgNTARWYQAFNRGLESVTNKYGQIAGFLVK--KGVLLFTFFVVALAAVTYfaKT 556
Cdd:NF033617  467 GAVIISGIVALTLTPMMCSRLLKANE-KPGRFARAVDRFFDGLTARYGRGLKWVLKhrPLTLVVALATLALLPLLY--VF 543
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   557 TSTAFVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLEMVEQEPGVDGVTLVNGYAfmtGASASNGASLFIKLHDWDMRN 636
Cdd:NF033617  544 IPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVG---GNPGDNTGFGIINLKPWDERD 620
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   637 AldgqhSAQAISQRINGRAAtELPQAIVFAMGPPAVPGmGAASGFEFVLEDTLGRSRTDLAMVMNDVIAEANKQPEISHT 716
Cdd:NF033617  621 V-----SAQEIIDRLRPKLA-KVPGMDLFLFPLQDLPG-GAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADV 693
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   717 FSTFRANVPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQRFHVRSSNG 796
Cdd:NF033617  694 DSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDG 773
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   797 EMIPLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAEVLPQGYQYEWTGMAYQEVLAGNQAIF 876
Cdd:NF033617  774 KLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKELLPSGISGSFQGAARAFQEEGSSLLF 853
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   877 AFALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEFAKVEREE 956
Cdd:NF033617  854 LFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRH 933
                         970       980       990      1000      1010      1020      1030
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 84379819   957 KDASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAFVQR 1032
Cdd:NF033617  934 QGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
PRK09579 PRK09579
multidrug efflux RND transporter permease subunit;
6-1033 4.11e-177

multidrug efflux RND transporter permease subunit;


Pssm-ID: 169983 [Multi-domain]  Cd Length: 1017  Bit Score: 544.43  E-value: 4.11e-177
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819     6 FIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMSSKSAN 85
Cdd:PRK09579    7 FIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQ 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    86 DGSYnLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPDLLMVLNFYSpnGEYDDQFLINYVNLNIKD 165
Cdd:PRK09579   87 NFSI-ISIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISFYS--EEMSNPQITDYLSRVIQP 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   166 QLARVSGISEVNVLGGGEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIGAapyanpQEVQFNLVTKGRLETA 245
Cdd:PRK09579  164 KLATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKG------EYVVTSINASTELKSA 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   246 DEFENVVLRANQDgSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTNFPEGVAY 325
Cdd:PRK09579  238 EAFAAIPVKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKV 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   326 EASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLILAIG 405
Cdd:PRK09579  317 SIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIG 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   406 IVVDDAILVIENVDTTMAKDPTisPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTICIAVVISS 485
Cdd:PRK09579  397 LVVDDAIVVVENIHRHIEEGKS--PFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISG 474
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   486 INALTLSPALCSLVLKQgGGNTARWYQAFNRGLESVTNKYGQIAGFLVKKGVLLFTFFVVALAAVTYFAKTTSTAFVPQE 565
Cdd:PRK09579  475 IVALTLSPMMCALLLRH-EENPSGLAHRLDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSELAPEE 553
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   566 DKGILLVNVQLPDAASLSRTEDVTEQLLEMVEQEPGVDGVTLVNGYafmTGASASNGASLfikLHDWDMRnaldgQHSAQ 645
Cdd:PRK09579  554 DQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQINGF---NGVQSGIGGFL---LKPWNER-----ERTQM 622
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   646 AISQRINGRaATELPQAIVFAMGPPAVPGMGAASGFEFVLEDTlgRSRTDLAMVMNDVIAEANKQPEISHTFSTFRANVP 725
Cdd:PRK09579  623 ELLPLVQAK-LEEIPGLQIFGFNLPSLPGTGEGLPFQFVINTA--NDYESLLQVAQRVKQRAQESGKFAFLDIDLAFDKP 699
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   726 HYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQRFHVRSSNGEMIPLSTLV 805
Cdd:PRK09579  700 EVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPLSTLI 779
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   806 TYDQIFEPDVAWRYNMYRSAVIQGQPApgYSSGDAIAAMERVAAEVLPQGYQYEWTGMAYQEVLAGNQAIFAFALALIFI 885
Cdd:PRK09579  780 TLSDRARPRQLNQFQQLNSAIISGFPI--VSMGEAIETVQQIAREEAPEGFAFDYAGASRQYVQEGSALWVTFGLALAII 857
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   886 YLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEFAKVEREEKDASIEDAA 965
Cdd:PRK09579  858 FLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQGLSRREAI 937
                         970       980       990      1000      1010      1020
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 84379819   966 VKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAFVQRK 1033
Cdd:PRK09579  938 EEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLLAKP 1005
CusA COG3696
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
1-1038 7.15e-147

Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];


Pssm-ID: 442911 [Multi-domain]  Cd Length: 1031  Bit Score: 465.27  E-value: 7.15e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    1 MLSR---FFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMI 77
Cdd:COG3696    1 MLNRiirFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   78 YMSSKSANDGSYnLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVR--------------MVGVTvkkrspdllmvlnf 143
Cdd:COG3696   81 EVRSISRFGLSV-VTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTpelgpistglgeiyQYTLE-------------- 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  144 ySPNGEYDDQFLINYVNLNIKDQLARVSGISEVNVLGGGEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIga 223
Cdd:COG3696  146 -SDPGKYSLMELRTLQDWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYI-- 222
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  224 apyaNPQEVQFNLVTKGRLETADEFENVVLrANQDGSTVYLKDIARVELGKKF------YDGNGkyrgqDASIVTLSLQS 297
Cdd:COG3696  223 ----ERGGQEYLVRGIGLIRSLEDIENIVV-KTRNGTPVLLRDVAEVRIGPAPrrgaatLNGEG-----EVVGGIVLMLK 292
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  298 DANALESGKAVMAMLDNLSTNFPEGVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVS 377
Cdd:COG3696  293 GENALEVIEAVKAKLAELKPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLS 372
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  378 LIGTFAVMQMTGFTINTVTLFGLILAIGIVVDDAILVIENVDTTMAKDPTISPRKATL----IAMKEVTGPIVTSTLVLL 453
Cdd:COG3696  373 LLFAFIVMRLFGISANLMSLGGLAIDFGIIVDGAVVMVENILRRLEENRAAGTPRERLevvlEAAREVRRPIFFATLIII 452
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  454 AVFIPVAMLPGITGIMYRQFALTICIAVVISSINALTLSPALCSLVLKqggGNTARWYQAFNRGLESVtnkYGQIAGFLV 533
Cdd:COG3696  453 LVFLPIFTLEGVEGKLFRPMALTVIFALLGALLLSLTLVPVLASLLLR---GKVPEKENPLVRWLKRL---YRPLLRWAL 526
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  534 KKGVLLFTFFVVALAAVTYFAKTTSTAFVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLEMVEQEPGVDGVtlvngyAF 613
Cdd:COG3696  527 RHPKLVLAVALVLLVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESV------VS 600
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  614 MTGASAS-------NGASLFIKLH---DWdmRNALDGQHSAQAISQRINGraatelpqaivfamgppaVPGMgaasGFEF 683
Cdd:COG3696  601 RTGRAEDatdpmgvNMSETFVILKprsEW--RSGRTKEELIAEMREALEQ------------------IPGV----NFNF 656
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  684 V------LEDTLGRSRTDLAM--------VMNDV---IAEANKQ-PEISHTFSTFRANVPHYYVDIDREKAQQLGIPLSE 745
Cdd:COG3696  657 SqpiqmrVDELLSGVRADVAVkifgddldVLRRLaeqIEAVLKTvPGAADVQVERVTGLPQLDIRIDRDAAARYGLNVAD 736
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  746 IFQTLQG-----NLGSLYVNDftmfgKNFRVTMQADSEHRSSMDDLQRFHVRSSNGEMIPLSTLVTYDQIFEPDVAWRYN 820
Cdd:COG3696  737 VQDVVETaiggkAVGQVYEGE-----RRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEVVEGPNQISREN 811
                        890       900       910       920       930       940       950       960
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  821 MYRSAVIQGQPApGYSSGDAIA-AMERVAAEV-LPQGYQYEWTGMAYQEVLAGN--QAIFAFALALIFIYLFMvaQYESW 896
Cdd:COG3696  812 GRRRIVVQANVR-GRDLGSFVAeAQAKVAEQVkLPPGYYIEWGGQFENLQRATArlAIVVPLALLLIFLLLYL--AFGSV 888
                        970       980       990      1000      1010      1020      1030      1040
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  897 TIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEFAKvEREEKDASIEDAAVKGGTLRFRAV 976
Cdd:COG3696  889 RDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYIN-QLRAEGLDLREAIIEGALERLRPV 967
                       1050      1060      1070      1080      1090      1100
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 84379819  977 NMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAFVQRKREKAH 1038
Cdd:COG3696  968 LMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLRRA 1029
PRK10614 PRK10614
multidrug efflux system subunit MdtC; Provisional
6-1036 1.77e-128

multidrug efflux system subunit MdtC; Provisional


Pssm-ID: 182589 [Multi-domain]  Cd Length: 1025  Bit Score: 416.05  E-value: 1.77e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819     6 FIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETS---VNGVEDMIYMSSK 82
Cdd:PRK10614    7 FIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSlgrIAGVNEMTSSSSL 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    83 sandGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQevrmvGVTVKKR--------SPDLLMVL--NFYSPNGEYDd 152
Cdd:PRK10614   87 ----GSTRIILQFDFDRDINGAARDVQAAINAAQSLLPS-----GMPSRPTyrkanpsdAPIMILTLtsDTYSQGQLYD- 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   153 qflinYVNLNIKDQLARVSGISEVNVLGGGEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIgaapyaNPQEV 232
Cdd:PRK10614  157 -----FASTQLAQTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAV------EDGTH 225
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   233 QFNLVTKGRLETADEFENVVLRANQdGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAML 312
Cdd:PRK10614  226 RWQIQTNDELKTAAEYQPLIIHYNN-GAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKL 304
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   313 DNLSTNFPEGVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTI 392
Cdd:PRK10614  305 PELRETIPAAIDLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSL 384
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   393 NTVTLFGLILAIGIVVDDAILVIENVDTTMakDPTISPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQ 472
Cdd:PRK10614  385 NNLSLMALTIATGFVVDDAIVVLENISRHL--EAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFRE 462
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   473 FALTICIAVVISSINALTLSPALCSLVLKQGGGNTARWYQAFNRGLESVTNKYGQIAGFLVKKGVLLFTFFVVALAAVTY 552
Cdd:PRK10614  463 FAVTLSVAIGISLLVSLTLTPMMCAWLLKSSKPREQKRLRGFGRMLVALQQGYGRSLKWVLNHTRWVGVVLLGTIALNVW 542
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   553 FAKTTSTAFVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLEMVEQEPGVDGVTlvnGYafmTGASASNGASLFIKLHDW 632
Cdd:PRK10614  543 LYISIPKTFFPEQDTGRLMGFIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVT---GF---TGGSRVNSGMMFITLKPL 616
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   633 DMRNaldgqHSAQAISQRINGRAATElPQAIVFAMGPP--AVPGMGAASGFEF-VLEDTLGRSRTdlamvMNDVIAEA-N 708
Cdd:PRK10614  617 SERS-----ETAQQVIDRLRVKLAKE-PGANLFLMAVQdiRVGGRQSNASYQYtLLSDDLAALRE-----WEPKIRKAlA 685
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   709 KQPEISHTFSTFRANVPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQR 788
Cdd:PRK10614  686 ALPELADVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEK 765
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   789 FHVRSSNGEMIPLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAEV-LPQGYQYEWTGMA--Y 865
Cdd:PRK10614  766 MFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIERAMTQLgVPSTVRGSFAGTAqvF 845
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   866 QEVLAGNQAIFAFALALIFIYLFMVaqYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAIL 945
Cdd:PRK10614  846 QETMNSQLILILAAIATVYIVLGIL--YESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIM 923
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   946 IVEFAKVEREEKDASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPG 1025
Cdd:PRK10614  924 MVDFALEAQRNGNLTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLLTLYTTPV 1003
                        1050
                  ....*....|.
gi 84379819  1026 FYAFVQRKREK 1036
Cdd:PRK10614 1004 VYLFFDRLRLR 1014
PRK10503 PRK10503
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
3-1032 3.59e-117

MdtB/MuxB family multidrug efflux RND transporter permease subunit;


Pssm-ID: 182501 [Multi-domain]  Cd Length: 1040  Bit Score: 386.01  E-value: 3.59e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819     3 SRFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMSSK 82
Cdd:PRK10503   13 SRLFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQ 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    83 SANdGSYNLNVTFDVGTDADMAQVNVQNRVAQIESKLPQEVRMVGVTVKKRSPD----LLMVLNFYSPNGEYDDQfliny 158
Cdd:PRK10503   93 SSG-GASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADppimTLAVTSTAMPMTQVEDM----- 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   159 VNLNIKDQLARVSGISEVNVLGGGEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIGAAPYAnpqevqFNLVT 238
Cdd:PRK10503  167 VETRVAQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRA------VTLSA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   239 KGRLETADEFENVVLrANQDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVMAMLDNLSTN 318
Cdd:PRK10503  241 NDQMQSAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTES 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   319 FPEGVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLF 398
Cdd:PRK10503  320 LPKSVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLM 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   399 GLILAIGIVVDDAILVIENVDTTMAKDPtiSPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLPGITGIMYRQFALTIC 478
Cdd:PRK10503  400 ALTIATGFVVDDAIVVIENISRYIEKGE--KPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLA 477
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   479 IAVVISSINALTLSPALCSLVLKQGG-GNTARWYQAFNRGLESVTNKYGQIAGFLVKK-----GVLLFTFFVVALAAVty 552
Cdd:PRK10503  478 VAILISAVVSLTLTPMMCARMLSQESlRKQNRFSRASERMFDRVIAAYGRGLAKVLNHpwltlSVALSTLLLTVLLWI-- 555
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   553 fakTTSTAFVPQEDKGILLVNVQLPDAASLSRTEDVTEQLLEMVEQEPGVDGVTLVNGyafMTGASAS-NGASLFIKLHD 631
Cdd:PRK10503  556 ---FIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVG---VDGTNPSlNSARLQINLKP 629
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   632 WDMRNaldgqHSAQAISQRINGRAATeLPQAIVF--AMGPPAVPGMGAASGFEFVLEDTlgrSRTDLAMVMNDVIAEANK 709
Cdd:PRK10503  630 LDERD-----DRVQKVIARLQTAVAK-VPGVDLYlqPTQDLTIDTQVSRTQYQFTLQAT---SLDALSTWVPKLMEKLQQ 700
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   710 QPEISHTFSTFRANVPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVNDFTMFGKNFRVTMQADSEHRSSMDDLQRF 789
Cdd:PRK10503  701 LPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTI 780
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   790 HVRSSNGEMIPLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQPAPGYSSGDAIAAMERVAAEV-LPQGY--QYEWTGMAYQ 866
Cdd:PRK10503  781 RLTSSDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLnLPADIttQFQGSTLAFQ 860
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   867 EVLAGnqAIFAFALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILI 946
Cdd:PRK10503  861 SALGS--TVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMM 938
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   947 VEFAKVEREEKDASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLIFAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGF 1026
Cdd:PRK10503  939 IDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTTPVI 1018

                  ....*.
gi 84379819  1027 YAFVQR 1032
Cdd:PRK10503 1019 YLLFDR 1024
2A0601 TIGR00914
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ...
4-1037 1.34e-87

heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 129992 [Multi-domain]  Cd Length: 1051  Bit Score: 304.76  E-value: 1.34e-87
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819      4 RFFIQRPKFALVISIILTLAGAISLAILPVAEYPKISPPSVSVSAFYTGASAEVVEQAIADPIETSVNGVEDMIYMSSKS 83
Cdd:TIGR00914    7 SFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLS 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819     84 ANDGSYnLNVTFDVGTDADMAQVNVQNRVAQIESKLPQ--------------EVRMVGVTVKKRSPdllmvlnfYSPNGE 149
Cdd:TIGR00914   87 RYGLSQ-VTVIFKDGTDLYFARQLVNERLQQARDNLPEgvspemgpistglgEIFLYTVEAEEGAR--------KKDGGA 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    150 YDDQFLINYVNLNIKDQLARVSGISEVNVLGGGEYSMRVWLDPEKMANLNLTTSDVYGALAEQNVQVAAGRIGAApyanp 229
Cdd:TIGR00914  158 YTLTDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERR----- 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    230 qEVQFNLVTKGRLETADEFENVVLrANQDGSTVYLKDIARVELGKKFYDGNGKYRGQDASIVTLSLQSDANALESGKAVM 309
Cdd:TIGR00914  233 -GEQYLVRAPGQVQSMDDIRNIVI-ATGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVG 310
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    310 AMLDNLSTNFPEGVAYEASYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTG 389
Cdd:TIGR00914  311 DKLETINKTLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQG 390
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    390 FTINTVTLFGliLAIGIVVDDAILVIENVDTTMAKDPTISPRKATLI--------AMKEVTGPIVTSTLVLLAVFIPVAM 461
Cdd:TIGR00914  391 ISANLMSLGA--LDFGLIVDGAVVIVENAHRRLAEAQHHHGRQLTLKerlhevfaASREVRRPLIFGQLIITLVFLPIFT 468
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    462 LPGITGIMYRQFALTICIAVVISSINALTLSPALCSLVLKQGGGNTARWYQAF-NRGLESVTNKygqiaGFLVKKGVLLF 540
Cdd:TIGR00914  469 LTGVEGKMFHPMAFTVVLALAGAMILSLTFVPAAVALFIRGKVAEKENRLMRVlKRRYEPLLER-----VLAWPAVVLGA 543
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    541 TFFVVALAAVTYFakTTSTAFVPQEDKG-ILLVNVQLPdaaSLSRTEDVTEQLL--EMVEQEPGVDGVTLVNGYAFMTGA 617
Cdd:TIGR00914  544 AAVSIVLVVWIAS--RVGGEFIPSLNEGdLAYQALRIP---GTSLAQSVAMQQTleKLIKSFPEVARVFAKTGTAEIATD 618
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    618 SAS-NGASLFIKLH---DWDmrnalDGQHSAQAISQRINGRAAtELPqAIVFAMGPPavpgmgaasgFEFVLEDTLGRSR 693
Cdd:TIGR00914  619 PMPpNASDTYIILKpesQWP-----EGKKTKEDLIEEIQEATV-RIP-GNNYEFTQP----------IQMRFNELISGVR 681
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    694 TDLAM-----VMNDVIAEANK-------QPEISHTFSTFRANVPHYYVDIDREKAQQLGIPLSEIFQTLQGNLGSLYVND 761
Cdd:TIGR00914  682 SDVAVkvfgdDLDDLDATAEKisavlkgVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGE 761
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    762 FTMFGKNFRVTMQADSEHRSSMDDLQRFHVR--SSNGEM---IPLSTLVTYDQIFEPDVAWRYNMYRSAVIQGQpAPGYS 836
Cdd:TIGR00914  762 TFEGDRRFDIVIRLPESLRESPQALRQLPIPlpLSEDARkqfIPLSDVADLRVSPGPNQISRENGKRRVVVSAN-VRGRD 840
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    837 SGDAIA-AMERVAAEV-LPQGYQYEWTGMaYQEVLAGN---QAIFAFALALIFIYLFMVaqYESWTIPIAIILVVPVATL 911
Cdd:TIGR00914  841 LGSFVDdAKKAIAEQVkLPPGYWITWGGQ-FEQLQSATkrlQIVVPVTLLLIFVLLYAA--FGNVKDALLVFTGIPFALT 917
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    912 GSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEFAKVEREEKdASIEDAAVKGGTLRFRAVNMTSWSFILGIFPLI 991
Cdd:TIGR00914  918 GGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLEEG-PSLDEAVYEGALTRVRPVLMTALVASLGFVPMA 996
                         1050      1060      1070      1080
                   ....*....|....*....|....*....|....*....|....*.
gi 84379819    992 FAAGAGHVSQNSLGISLIGGLLCVLLAGTFLIPGFYAFVQRKREKA 1037
Cdd:TIGR00914  997 IATGTGAEVQRPLATVVIGGIITATLLTLFVLPALYRLVHRRRHKG 1042
MMPL COG1033
Predicted exporter protein, RND superfamily [General function prediction only];
252-1037 6.11e-20

Predicted exporter protein, RND superfamily [General function prediction only];


Pssm-ID: 440656 [Multi-domain]  Cd Length: 767  Bit Score: 95.70  E-value: 6.11e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  252 VLRANQDGSTVYLKDIARVELGKKFYDGNgkYRGQDAS----IVTLSLQSDANALESGKAVMAMLDNLSTNFPEGVAYEA 327
Cdd:COG1033  125 LIPDELPASPEELAELREKVLSSPLYVGR--LVSPDGKatliVVTLDPDPLSSDLDRKEVVAEIRAIIAKYEDPGVEVYL 202
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  328 SYDTtVFVAESIKGVVKTLIE----AILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTIN--TVTLFGLI 401
Cdd:COG1033  203 TGFP-VLRGDIAEAIQSDLAIffplALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSplTILVPPLL 281
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  402 LAIGIvvDDAILVIENVDTTMAKdpTISPRKATLIAMKEVTGPIVTSTLVLLAVFIpvAMLpgITGI-MYRQFALTICIA 480
Cdd:COG1033  282 LAIGI--DYGIHLLNRYREERRK--GLDKREALREALRKLGPPVLLTSLTTAIGFL--SLL--FSDIpPIRDFGIVAAIG 353
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  481 VVISSINALTLSPALCSLVLKqgggntARWYQAFNRGLESVTNKYGQIAGFLVKKGVLLFTFFVVALAAVTYfakttsta 560
Cdd:COG1033  354 VLLAFLTSLTLLPALLSLLPR------PKPKTRRLKKPPELGRLLAKLARFVLRRPKVILVVALVLAVVSLY-------- 419
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  561 fvpqedkGILLVNVqlpdaaslsrtedvteqllemveqepgvdgvtlvngyafmtgasasngaslfiklhDWDMRNALDG 640
Cdd:COG1033  420 -------GISRLKV--------------------------------------------------------EYDFEDYLPE 436
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  641 QHSAQAISQRINGRaatelpqaivfamgppavpgMGAASGFEFVLEDTLGRSRTDLAMV--MNDVIAEANKQPEISHTFS 718
Cdd:COG1033  437 DSPIRQDLDFIEEN--------------------FGGSDPLEVVVDTGEPDGLKDPEVLkeIDRLQDYLESLPEVGKVLS 496
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  719 tfranvphyYVDIdrekaqqlgipLSEIFQTLQGNLGSLYVndftmFGKNFRVTMQADSEHRSSMDDLqrfhvrssngem 798
Cdd:COG1033  497 ---------LADL-----------VKELNQALNEGDPKYYA-----LPESRELLAQLLLLLSSPPGDD------------ 539
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  799 ipLSTLVTYDqifepdvawrynmYRSAVIQGQPAPgYSSGDAIAAMERVAAEV----LPQGYQYEWTGMAY-----QEVL 869
Cdd:COG1033  540 --LSRFVDED-------------YSAARVTVRLKD-LDSEEIKALVEEVRAFLaenfPPDGVEVTLTGSAVlfaaiNESV 603
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  870 AGNQaIFAFALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEF 949
Cdd:COG1033  604 IESQ-IRSLLLALLLIFLLLLLAFRSLRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSR 682
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  950 AKVEReEKDASIEDAAVKggTLRF--RAVNMTSWSFILGIFPLIFAAgagHVSQNSLGISLIGGLLCVLLAGTFLIPGFY 1027
Cdd:COG1033  683 YREER-RKGGDLEEAIRR--ALRTtgKAILFTSLTLAAGFGVLLFSS---FPPLADFGLLLALGLLVALLAALLLLPALL 756
                        810
                 ....*....|
gi 84379819 1028 AFVQRKREKA 1037
Cdd:COG1033  757 LLLDPRIAKK 766
MMPL COG1033
Predicted exporter protein, RND superfamily [General function prediction only];
822-1039 4.33e-09

Predicted exporter protein, RND superfamily [General function prediction only];


Pssm-ID: 440656 [Multi-domain]  Cd Length: 767  Bit Score: 60.64  E-value: 4.33e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  822 YRSAVIQGQPAPGYSSGD-----AIAAMERVAAEVLPQGYQYEWTGMAY-----QEVLAGNQAIFaFALALIFIYLFMVA 891
Cdd:COG1033  159 GKATLIVVTLDPDPLSSDldrkeVVAEIRAIIAKYEDPGVEVYLTGFPVlrgdiAEAIQSDLAIF-FPLALLLILLLLFL 237
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  892 QYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAI-LIVEFakveREE--KDASIEDAAVKg 968
Cdd:COG1033  238 FFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIhLLNRY----REErrKGLDKREALRE- 312
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 84379819  969 gTLR--FRAVNMTSWSFILGIFPLIFAA-GAGHvsqnSLGISLIGGLLCVLLAGTFLIPGFYAFVQRKREKAHG 1039
Cdd:COG1033  313 -ALRklGPPVLLTSLTTAIGFLSLLFSDiPPIR----DFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRR 381
YdfJ COG2409
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ...
288-608 5.93e-09

Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];


Pssm-ID: 441964 [Multi-domain]  Cd Length: 697  Bit Score: 60.16  E-value: 5.93e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  288 ASIVTLSLQSDANAlESGKAVMAMLDNLSTNFPEGVAYEASYDTTV---FVAESIKGVVKTLIEAILLVIAVTYLFLGSA 364
Cdd:COG2409  115 AALVTVTLDGDAGD-EAAEAVDALRDAVAAAPAPGLTVYVTGPAALaadLNEAFEEDLGRAELITLPVALVVLLLVFRSL 193
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  365 RATLIPVVAIPVSLIGTFAV-------MQMTGFTINTVTLFGLilaiGIVVDDAILVI----ENVDTTMakdptiSPRKA 433
Cdd:COG2409  194 VAALLPLLTAGLAVGVALGLlallaafTDVSSFAPNLLTMLGL----GVGIDYALFLVsryrEELRAGE------DREEA 263
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  434 TLIAMKEVTGPIVTSTLvllAVFIPVAMLpGITGI-MYRQFALTICIAVVISSINALTLSPALCSLVlkqgGGNTARWYQ 512
Cdd:COG2409  264 VARAVATAGRAVLFSGL---TVAIALLGL-LLAGLpFLRSMGPAAAIGVAVAVLAALTLLPALLALL----GRRVFWPRR 335
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  513 AFNRGLESVTNKYGQ-IAGFLVKKGVLLFTFFVVALAAVTYFAKTTSTAFV----------------------PQEDKGI 569
Cdd:COG2409  336 PRRRRAAAPESGFWRrLARAVVRRPVPVLVAAVAVLLALALPALGLRLGLPdadslpadspsrqgydalaehfPPGSNGP 415
                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 84379819  570 LLVNVQLPDAASLSRTEDVtEQLLEMVEQEPGVDGVTLV 608
Cdd:COG2409  416 LTVVVESDDDLDPADLAAL-DALAAALAAVPGVASVQPP 453
2A0604s01 TIGR00916
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ...
336-489 5.49e-08

protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273336 [Multi-domain]  Cd Length: 192  Bit Score: 54.18  E-value: 5.49e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    336 AESIKGVVKTLIEAILLVIAvtYLFLGSARATLIPVVAIPVS-LIGTFAVMQMTGFTINTVTLFGLILAIGIVVDDAILV 414
Cdd:TIGR00916   43 GELIKAGIIALLIGLVLVLL--YMLLRYEWRGAIAAIAALVHdVILILGVLSLFGATLTLPGIAGLLTIIGYSVDDTVVI 120
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 84379819    415 IENVDTTMAKDPTISPRKATLIAMKEVTGPIVTSTLVllaVFIPVAMLPGITGIMYRQFALTICIAVVISSINAL 489
Cdd:TIGR00916  121 FDRIREELRKYKGRTFREAINLGINQTLSRIIDTNVT---TLLAVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
317-499 5.64e-07

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 53.69  E-value: 5.64e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    317 TNFPEGVAYEASYDTTV---FVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTIN 393
Cdd:TIGR00921  167 TNPPSGKFLDVTGSPAInydIEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLY 246
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    394 TVTLFGLILAIGIVVDDAILVIENVDTTMAKDPTISprKATLIAMKEvTGPIV-----TSTLVLLAVFIPVamLPgitgi 468
Cdd:TIGR00921  247 ATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKG--EAIVTAVRR-TGRAVliallTTSAGFAALALSE--FP----- 316
                          170       180       190
                   ....*....|....*....|....*....|.
gi 84379819    469 MYRQFALTICIAVVISSINALTLSPALCSLV 499
Cdd:TIGR00921  317 MVSEFGLGLVAGLITAYLLTLLVLPALLQSI 347
secD TIGR01129
protein-export membrane protein SecD; Members of this family are highly variable in length ...
336-495 1.48e-05

protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273456 [Multi-domain]  Cd Length: 397  Bit Score: 48.44  E-value: 1.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    336 AESIKGVVKTLIEAILLVIAVTYLFLGSAraTLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLILAIGIVVDDAILVI 415
Cdd:TIGR01129  244 ADSIEAGIKAGLIGLVLVLVFMILYYRLF--GLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIY 321
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    416 ENVDTTMAKDptISPRKATLIAMKEVTGPIVTSTLV-LLAVFIPVAMLPG-ITGimyrqFALTICIAVVISSINALTLSP 493
Cdd:TIGR01129  322 ERIKEELRLG--KSVRQAIEAGFERAFSTIFDANITtLIAALILYVFGTGpVKG-----FAVTLAIGIIASLFTALVFTR 394

                   ..
gi 84379819    494 AL 495
Cdd:TIGR01129  395 LL 396
PRK14726 PRK14726
protein translocase subunit SecDF;
336-492 2.68e-05

protein translocase subunit SecDF;


Pssm-ID: 237805 [Multi-domain]  Cd Length: 855  Bit Score: 48.18  E-value: 2.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   336 AESIK-GVVKTLIEAILLVIA--VTYLFLGsaratLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLILAIGIVVDDAI 412
Cdd:PRK14726  368 ADSIAaGLVAGLIAAILVAALmiGFYGFLG-----VIAVIALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIGMAVDSNV 442
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   413 LVIENVDTTMAKdpTISPRKATLIAMKEVTGPIVTSTlvlLAVFIPVAMLPGITGIMYRQFALTICIAVVISSINALTLS 492
Cdd:PRK14726  443 LIYERIREEEKT--GHSLIQALDRGFSRALATIVDAN---VTILIAAVILFFLGSGAVRGFAVTLAVGILTTVFTAFTLT 517
Patched pfam02460
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ...
343-499 6.67e-05

Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.


Pssm-ID: 308203 [Multi-domain]  Cd Length: 793  Bit Score: 46.96  E-value: 6.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    343 VKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLILAIGIVVDDAILVIENVDTTM 422
Cdd:pfam02460  642 IQNIVITLICMFIVCFLFIPNPPCVFVITLAIASIDIGVFGFLSLWGVDLDPISMITIIMSIGFSVDFSAHIAYHFVRSR 721
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    423 AKDptisPRKATLIAMKEVTGPIV---TSTL--VLLAVFIPVAMLpgitgimyRQFALTICIAVVISSINALTLSPALCS 497
Cdd:pfam02460  722 GDT----PAERVVDALEALGWPVFqggLSTIlgVLVLLFVPSYMV--------VVFFKTVFLVVAIGLLHGLFILPIILS 789

                   ..
gi 84379819    498 LV 499
Cdd:pfam02460  790 LF 791
actII TIGR00833
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ...
288-498 7.99e-05

Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 129913 [Multi-domain]  Cd Length: 910  Bit Score: 46.89  E-value: 7.99e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    288 ASIVTLSLQSDAN---ALESGKAVMAMLDNlsTNFPEGVAYEASYD--TTVFVAESI-KGVVKTLIEAILLVIAVTYLFL 361
Cdd:TIGR00833  117 ATIIIVNLAGEKGqkeAQEAINAVRRIVEQ--TNAPDGLTVHVTGPlaTIADILESGdKDMNRITATTGIIVLIILLLVY 194
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    362 GSARATLIPVVAIPVSLI---GTFAVMQMTGF-TINTVTLFGLI-LAIGIVVDDAILVIENVDTTMAKDptISPRKATLI 436
Cdd:TIGR00833  195 RSPITMLVPLVSVGFSVVvaqGIVSLLGIPGLiGVNAQTTVLLTaLVIGAGTDYAVFLTGRYHEERRKG--ESLEEAAAE 272
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 84379819    437 AMKEVTGPIVTSTLVLLAVF--IPVAMLPgitgiMYRQFALTICIAVVISSINALTLSPALCSL 498
Cdd:TIGR00833  273 ALRGTGKAILGSALTVAVAFlaLSLARLP-----SFKTLGVSCAVGVLVALLNAVTLTPALLTL 331
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
319-498 3.51e-04

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 44.44  E-value: 3.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    319 FPEGVAYEA---SYDTTVFVAESIKGVVKTLIEAILLVIAVTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTG--FTIN 393
Cdd:TIGR00921  543 PPPGVKVGVtglPVAFAEMHELVNEGMRRMTIAGAILVLMILLAVFRNPIKAVFPLIAIGSGILWAIGLMGLRGipSFLA 622
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    394 TVTLFGLILAIGIvvDDAILVIENVDTTMAKdptISPRKATLIAMkEVTGP-IVTSTLVLLAVFIpvAMLPGITGIMyRQ 472
Cdd:TIGR00921  623 MATTISIILGLGM--DYSIHLAERYFEERKE---HGPKEAITHTM-ERTGPgILFSGLTTAGGFL--SLLLSHFPIM-RN 693
                          170       180
                   ....*....|....*....|....*.
gi 84379819    473 FALTICIAVVISSINALTLSPALCSL 498
Cdd:TIGR00921  694 FGLVQGIGVLSSLTAALVVFPALLVL 719
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
853-1044 4.06e-04

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 44.44  E-value: 4.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    853 PQGYQYEWTG---MAYQ-EVLAGNQAIFAFALALIFIYLFMVAQYESWT---IPIAIILVVPVATLGsflALNLTGTPLN 925
Cdd:TIGR00921  170 PSGKFLDVTGspaINYDiEREFGKDMGTTMAISGILVVLVLLLDFKRWWrplLPLVIILFGVAWVLG---IMGWLGIPLY 246
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    926 LYAQIGLVLLIALAAKNAILIVEFAKVEREEKDASiEDAAVKGGTLRFRAVNMTSWSFILGiFPLIFAAGAGHVSQNSLG 1005
Cdd:TIGR00921  247 ATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAK-GEAIVTAVRRTGRAVLIALLTTSAG-FAALALSEFPMVSEFGLG 324
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 84379819   1006 IsLIGGLLCVLLAGTFL------IPGFYAFVQRKREKAHGGTTKL 1044
Cdd:TIGR00921  325 L-VAGLITAYLLTLLVLpallqsIDIGREKVKKEIIAIGGKSSEI 368
SecD COG0342
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ...
336-501 4.52e-04

Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440111 [Multi-domain]  Cd Length: 434  Bit Score: 43.95  E-value: 4.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  336 AESIKGVVKTLIEAILLVIAVTYLFLGSARatLIPVVAIPVSLIGTFAVMQMTGFTIntvTL---FGLILAIGIVVDDAI 412
Cdd:COG0342  267 ADSIEKGLIAGLIGLLLVALFMLLYYRLPG--LVANIALALNVVLLLGVLSLLGATL---TLpgiAGIILTIGMAVDANV 341
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  413 LVIENVDTTMAKDptISPRKATLIAMKEVTGPIVTSTLVLLAVFIPVAMLpGITGImyRQFALTICIAVVISSINALTLS 492
Cdd:COG0342  342 LIFERIREELRAG--RSLRAAIEAGFKRAFSTILDANVTTLIAAVVLFVL-GTGPV--KGFAVTLILGILISMFTAVPVT 416

                 ....*....
gi 84379819  493 PALCSLVLK 501
Cdd:COG0342  417 RPLLNLLLG 425
MMPL pfam03176
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ...
288-510 4.99e-04

MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.


Pssm-ID: 308676 [Multi-domain]  Cd Length: 332  Bit Score: 43.43  E-value: 4.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    288 ASIVTLSLQSDAN---ALESGKAVMAMLDNLSTnfPEGVAYEASYDTTVFV--AESIKGVVKTLIEAILLVIAVTYLFL- 361
Cdd:pfam03176   86 AAYVVVTLEGDPGtteADESVAAVRDAVEQAPP--PEGLKAYLTGPAATVAdlRDAGDRDLGLIEAVTLVVIFIILLIVy 163
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    362 GSARATLIPVVAIPVSLIGTFAVMQMT----GFTINTVTL-FGLILAIGIVVDDAILVIENVDTTMAKDPTispRKATLI 436
Cdd:pfam03176  164 RSVVAALLPLLTVGLSLGAAQGLVAILahilGIGLSTFALnLLVVLLIAVGTDYALFLVSRYREELRAGED---REEAVI 240
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    437 AMKEVTGPIVT-STLVLLAVFIP--VAMLPgitgiMYRQFALTICIAVVISSINALTLSPALCSLV-----LKQGGGNTA 508
Cdd:pfam03176  241 RAVRGTGKVVTaAGLTVAIAMLAlsFARLP-----VFAQVGPTIAIGVLVDVLAALTLLPALLALLgrwglWPPKRDRTA 315

                   ..
gi 84379819    509 RW 510
Cdd:pfam03176  316 RW 317
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
336-555 5.35e-04

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 44.07  E-value: 5.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   336 AESIKGVVKTLIEAILLV---IAVTYLFLGsaratLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLILAIGIVVDDAI 412
Cdd:PRK13024  262 QDAIDAGIIAGIIGFALIflfMLVYYGLPG-----LIANIALLLYIFLTLGALSSLGAVLTLPGIAGLVLGIGMAVDANV 336
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   413 LVIENVDTTMAKDPTIspRKATLIAMKEVTGPI----VTSTLVLLAVFI----PVamlpgitgimyRQFALTICIAVVIS 484
Cdd:PRK13024  337 LIFERIKEELRKGKSL--KKAFKKGFKNAFSTIldsnITTLIAAAILFFfgtgPV-----------KGFATTLIIGILAS 403
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 84379819   485 SINALTLSPALCSLVLKQGGGNTARWYQAFNR--GLESVTNKYGQIAGFLVKKGVLLFTFFVVALAAVTYFAK 555
Cdd:PRK13024  404 LFTAVFLTRLLLELLVKRGDKKPFLFGVKKKKihNINEGVTIFDRIDFVKKRKWFLIFSIVLVIAGIIIFFIF 476
2A060602 TIGR00918
The Eukaryotic (Putative) Sterol Transporter (EST) Family;
346-499 1.56e-03

The Eukaryotic (Putative) Sterol Transporter (EST) Family;


Pssm-ID: 273338 [Multi-domain]  Cd Length: 1145  Bit Score: 42.56  E-value: 1.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819    346 LIEAILLVIA--VTYLFLGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLILAIGIVVDDAILVIENVDTTMA 423
Cdd:TIGR00918  969 LSISVVLACTflVCALLLLNPWTAGLIVLVLALMTVELFGMMGLLGIKLSAIPVVILIASVGIGVEFTVHIALGFLTAIG 1048
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 84379819    424 kdptiSPRKATLIAMKEVTGPIVTSTL-VLLAVFipvaMLPGIT-GIMYRQFALTICIAVVISSINALTLSPALCSLV 499
Cdd:TIGR00918 1049 -----DRNRRAVLALEHMFAPVLDGALsTLLGVL----MLAGSEfDFIVRYFFAVLAVLTCLGVLNGLVLLPVLLSMF 1117
COG4258 COG4258
Predicted exporter [General function prediction only];
281-412 1.77e-03

Predicted exporter [General function prediction only];


Pssm-ID: 443400 [Multi-domain]  Cd Length: 783  Bit Score: 42.53  E-value: 1.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  281 GKYRGQDASIVTLSLQSDANALEsgkavmAMLDNLstnfpEGVAY---EASYDTtvfVAESIKGVVKTLIEAILLVIAVT 357
Cdd:COG4258  590 GRKDGQWAALVPLRGVDDAAALR------AAAAGL-----PGVRLvdrKAESSS---LFGRYRNDALWLLLLALLLILLL 655
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 84379819  358 YLF-LGSARATLIPVVAIPVSLIGTFAVMQMTGFTINTVTLFGLILAIGIVVDDAI 412
Cdd:COG4258  656 LLLrLRSLRRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYAL 711
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
872-1036 2.72e-03

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 41.76  E-value: 2.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   872 NQAIFAFALALIFIYLFMVAQYESWTIPIAIILVVPVA-TLGSFLALNLTGTPLNLyaqIGLVLLIALAAKNAILIVEFA 950
Cdd:PRK13024  266 DAGIIAGIIGFALIFLFMLVYYGLPGLIANIALLLYIFlTLGALSSLGAVLTLPGI---AGLVLGIGMAVDANVLIFERI 342
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   951 KvEREEKDASIEDAAVKGGTLRFRAV---NMTswSFILGIfpLIFAAGAGHVsqNSLGISLIGGLLCVLLAGTFLIPGFY 1027
Cdd:PRK13024  343 K-EELRKGKSLKKAFKKGFKNAFSTIldsNIT--TLIAAA--ILFFFGTGPV--KGFATTLIIGILASLFTAVFLTRLLL 415

                  ....*....
gi 84379819  1028 AFVQRKREK 1036
Cdd:PRK13024  416 ELLVKRGDK 424
COG4258 COG4258
Predicted exporter [General function prediction only];
872-1025 4.07e-03

Predicted exporter [General function prediction only];


Pssm-ID: 443400 [Multi-domain]  Cd Length: 783  Bit Score: 40.99  E-value: 4.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  872 NQAIFAFALALIFIYLFMVAQYESWTIPIAIILVVPVATLGSFLALNLTGTPLNLYAQIGLVLLIALAAKNAILIVEfak 951
Cdd:COG4258  639 NDALWLLLLALLLILLLLLLRLRSLRRALRVLLPPLLAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYALFFTE--- 715
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 84379819  952 vereekdasiedAAVKGGTLR--FRAVNMTSWSFILGIFPLIFAAgagHVSQNSLGISLIGGLLCVLLAGTFLIPG 1025
Cdd:COG4258  716 ------------GLLDKGELArtLLSILLAALTTLLGFGLLAFSS---TPALRSFGLTVLLGILLALLLAPLLAPR 776
YdfJ COG2409
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ...
287-483 5.41e-03

Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];


Pssm-ID: 441964 [Multi-domain]  Cd Length: 697  Bit Score: 40.90  E-value: 5.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  287 DASIVTLSLQSDANALESGKAVMAMLDnlstnfpegVAYEASYDTTVFVA-------ESIKGVVKTLIEAILLVIAVTYL 359
Cdd:COG2409  462 DAARLQVVPDGDPDSPEAIDLVDRLRD---------AAAPALEGAEVLVGgttavniDISDALADDLPLVIPVVLGLIFL 532
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819  360 FLGSA-RATLIPVVAIP---VSLIGTFAVM--------QMTGFTINTVTLFGLILAIGIVV----DDAILVI----ENVD 419
Cdd:COG2409  533 LLLLLfRSVVAPLKAVLtnlLSLGAALGVLvlvfqhgwLLLGFTPGPLDSFVPLLLFVILFglgmDYEVFLVsrirEEYD 612
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 84379819  420 TTMakdptiSPRKATLIAMkEVTGPIVTST-LVLLAVFipVAMLP-GITGImyRQFALTICIAVVI 483
Cdd:COG2409  613 RGG------GTREAVIRGL-ARTGRVITSAaLIMAAVF--AAFATsPLVFL--KQIGFGLAVGVLL 667
secD PRK05812
preprotein translocase subunit SecD; Reviewed
336-495 7.90e-03

preprotein translocase subunit SecD; Reviewed


Pssm-ID: 235615 [Multi-domain]  Cd Length: 462  Bit Score: 39.82  E-value: 7.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   336 AESIKGVVKTLIEAILLVIA---VTYLFLGsaratLIPVVAIPVSLIGTFAVMQMTGFTIntvTL---FGLILAIGIVVD 409
Cdd:PRK05812  293 ADSIRAGLIAGLIGLALVLLfmiLYYRLFG-----LIANIALVANLVLILAVLSLLGATL---TLpgiAGIVLTIGMAVD 364
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 84379819   410 DAILVIENVdttmaKDpTI----SPRKATLIAMKEVTGPIVTSTLV-LLAVFI-------PVamlpgitgimyRQFALTI 477
Cdd:PRK05812  365 ANVLIFERI-----RE-ELregrSLRSAIEAGFKRAFSTILDSNITtLIAAIIlyalgtgPV-----------KGFAVTL 427
                         170
                  ....*....|....*...
gi 84379819   478 CIAVVISSINALTLSPAL 495
Cdd:PRK05812  428 GIGILTSMFTAITVTRAL 445
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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