NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|119620631|gb|EAX00226|]
View 

tetratricopeptide repeat domain 7A, isoform CRA_a [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TTC7_N super family cl44857
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 28-369 4.14e-138

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


The actual alignment was detected with superfamily member pfam19440:

Pssm-ID: 466084  Cd Length: 386  Bit Score: 414.56  E-value: 4.14e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631   28 DDFGKLLLAEALLEQCLKENHAKIKDSMpllEKNEPKMSEAKNYLSSILNHGRLSPQYMCEAMLILGKLHYVEGSYRDAI 107
Cdd:pfam19440  43 DDMANLLLGEGKLEQYLKENPPILENST---EKNQPKLSEAKKHLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREAL 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  108 SMYARAGIDDMSMENKPLYQMRLLSEAFVIKGLSLERLPNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNS 187
Cdd:pfam19440 120 NMYARAGLDDLTLKELPVYRLRLLAEAYAIKGLCLEKQAVSSSSRVRLAEREEEMITCYEKAGDIALLYLQELERINSNT 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  188 TSRHLK-GCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECY 266
Cdd:pfam19440 200 QNRSPKpGPPSQEQELGFFLETALQRAYVLYFKKGNLARGVGRYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSY 279

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  267 WSPLSHPLPEFMGKEES-SFATQA---LRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSL 342
Cdd:pfam19440 280 WNPLEDPPPQSLLDEPLkGTNTKNytpSRKPRVYSGENIFCPQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISL 359

                         330       340
                  ....*....|....*....|....*..
gi 119620631  343 QNAAAIYDLLSITLGRRGQYVMLSECL 369
Cdd:pfam19440 360 QNATAVYDLLTIAMGRRGQYEMLSECL 386
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 676-813 3.92e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 95.45  E-value: 3.92e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 676 LEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLML 755
Cdd:COG3914   77 LAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 119620631 756 SRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSP 813
Cdd:COG3914  157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNA 214
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 426-595 7.38e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 52.69  E-value: 7.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 426 GSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQATDATLKSKQDelHRKALQTLERAQQLAPSDPQVILYVS 505
Cdd:COG3914   42 GLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGR--YEEALALYRRALALNPDNAEALFNLG 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 506 LQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEA 585
Cdd:COG3914  120 NLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEA 199

                        170
                 ....*....|
gi 119620631 586 LVTCRQVLRL 595
Cdd:COG3914  200 IAAYRRALEL 209
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 343-438 6.52e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.56  E-value: 6.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 343 QNAAAiYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAK 422
Cdd:COG4783   36 DNPEA-FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLAR 114

                         90
                 ....*....|....*.
gi 119620631 423 VCIGSLRWLEEAEHFA 438
Cdd:COG4783  115 AYRALGRPDEAIAALE 130
 
Name Accession Description Interval E-value
TTC7_N pfam19440
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 28-369 4.14e-138

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


Pssm-ID: 466084  Cd Length: 386  Bit Score: 414.56  E-value: 4.14e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631   28 DDFGKLLLAEALLEQCLKENHAKIKDSMpllEKNEPKMSEAKNYLSSILNHGRLSPQYMCEAMLILGKLHYVEGSYRDAI 107
Cdd:pfam19440  43 DDMANLLLGEGKLEQYLKENPPILENST---EKNQPKLSEAKKHLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREAL 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  108 SMYARAGIDDMSMENKPLYQMRLLSEAFVIKGLSLERLPNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNS 187
Cdd:pfam19440 120 NMYARAGLDDLTLKELPVYRLRLLAEAYAIKGLCLEKQAVSSSSRVRLAEREEEMITCYEKAGDIALLYLQELERINSNT 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  188 TSRHLK-GCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECY 266
Cdd:pfam19440 200 QNRSPKpGPPSQEQELGFFLETALQRAYVLYFKKGNLARGVGRYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSY 279

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  267 WSPLSHPLPEFMGKEES-SFATQA---LRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSL 342
Cdd:pfam19440 280 WNPLEDPPPQSLLDEPLkGTNTKNytpSRKPRVYSGENIFCPQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISL 359

                         330       340
                  ....*....|....*....|....*..
gi 119620631  343 QNAAAIYDLLSITLGRRGQYVMLSECL 369
Cdd:pfam19440 360 QNATAVYDLLTIAMGRRGQYEMLSECL 386
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 676-813 3.92e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 95.45  E-value: 3.92e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 676 LEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLML 755
Cdd:COG3914   77 LAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 119620631 756 SRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSP 813
Cdd:COG3914  157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNA 214
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 570-821 5.24e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 56.53  E-value: 5.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  570 FTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGGLEKDGSFGEGlTMKKQSGMHLTLPDAhDADSGSRRASSIAAS 649
Cdd:TIGR00990 242 FAESKAKEILETKPENLPSVTFVGNYLQSFRPKPRPAGLEDSNELDEE-TGNGQLQLGLKSPES-KADESYEEAARAFEK 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  650 RLE-------EAMS-ELTMPSSVLKQGP----------MQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSH 711
Cdd:TIGR00990 320 ALDlgklgekEAIAlNLRGTFKCLKGKHlealadlsksIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDP 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  712 SVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQA 791
Cdd:TIGR00990 400 DIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLD 479

                         250       260       270
                  ....*....|....*....|....*....|
gi 119620631  792 QGQNEAAVDCFLTALELEASSPVLPFSIIP 821
Cdd:TIGR00990 480 QNKFDEAIEKFDTAIELEKETKPMYMNVLP 509
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 426-595 7.38e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 52.69  E-value: 7.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 426 GSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQATDATLKSKQDelHRKALQTLERAQQLAPSDPQVILYVS 505
Cdd:COG3914   42 GLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGR--YEEALALYRRALALNPDNAEALFNLG 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 506 LQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEA 585
Cdd:COG3914  120 NLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEA 199

                        170
                 ....*....|
gi 119620631 586 LVTCRQVLRL 595
Cdd:COG3914  200 IAAYRRALEL 209
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 472-814 5.11e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 5.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  472 LKSKQDElhrKALQTLERAQQLAPSDPQViLYVSLQLALVR-QISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQH 550
Cdd:TIGR02917 238 IEAGEFE---EAEKHADALLKKAPNSPLA-HYLKALVDFQKkNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQ 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  551 ALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGG---------------LEKDGSFG 615
Cdd:TIGR02917 314 AYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGeaylalgdfekaaeyLAKATELD 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  616 EGLTMKK-QSGM-HLTLPDAHDADsgsrrASSIAASRLEEAM--SELTMPSSVLKQGPM------------------QLW 673
Cdd:TIGR02917 394 PENAAARtQLGIsKLSQGDPSEAI-----ADLETAAQLDPELgrADLLLILSYLRSGQFdkalaaakklekkqpdnaSLH 468

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  674 TTLEQIWLQAAELFMEQQHLKEAgfcIQEAAGLFPTSHSVLymrgRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGL 753
Cdd:TIGR02917 469 NLLGAIYLGKGDLAKAREAFEKA---LSIEPDFFPAAANLA----RIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAG 541

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  754 MLSRLGHKS---------------------------LAQK-------VLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAV 799
Cdd:TIGR02917 542 LYLRTGNEEeavawlekaaelnpqeiepalalaqyyLGKGqlkkalaILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAV 621

                         410
                  ....*....|....*
gi 119620631  800 DCFLTALELEASSPV 814
Cdd:TIGR02917 622 SSFKKLLALQPDSAL 636
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 343-438 6.52e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.56  E-value: 6.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 343 QNAAAiYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAK 422
Cdd:COG4783   36 DNPEA-FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLAR 114

                         90
                 ....*....|....*.
gi 119620631 423 VCIGSLRWLEEAEHFA 438
Cdd:COG4783  115 AYRALGRPDEAIAALE 130
TPR_11 pfam13414
TPR repeat;
724-759 1.67e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 1.67e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 119620631  724 KGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLG 759
Cdd:pfam13414   7 QGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
 
Name Accession Description Interval E-value
TTC7_N pfam19440
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 28-369 4.14e-138

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


Pssm-ID: 466084  Cd Length: 386  Bit Score: 414.56  E-value: 4.14e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631   28 DDFGKLLLAEALLEQCLKENHAKIKDSMpllEKNEPKMSEAKNYLSSILNHGRLSPQYMCEAMLILGKLHYVEGSYRDAI 107
Cdd:pfam19440  43 DDMANLLLGEGKLEQYLKENPPILENST---EKNQPKLSEAKKHLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREAL 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  108 SMYARAGIDDMSMENKPLYQMRLLSEAFVIKGLSLERLPNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNS 187
Cdd:pfam19440 120 NMYARAGLDDLTLKELPVYRLRLLAEAYAIKGLCLEKQAVSSSSRVRLAEREEEMITCYEKAGDIALLYLQELERINSNT 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  188 TSRHLK-GCHPLDYELTYFLEAALQSAYVKNLKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECY 266
Cdd:pfam19440 200 QNRSPKpGPPSQEQELGFFLETALQRAYVLYFKKGNLARGVGRYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSY 279

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  267 WSPLSHPLPEFMGKEES-SFATQA---LRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSL 342
Cdd:pfam19440 280 WNPLEDPPPQSLLDEPLkGTNTKNytpSRKPRVYSGENIFCPQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISL 359

                         330       340
                  ....*....|....*....|....*..
gi 119620631  343 QNAAAIYDLLSITLGRRGQYVMLSECL 369
Cdd:pfam19440 360 QNATAVYDLLTIAMGRRGQYEMLSECL 386
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 676-813 3.92e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 95.45  E-value: 3.92e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 676 LEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLML 755
Cdd:COG3914   77 LAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 119620631 756 SRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSP 813
Cdd:COG3914  157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNA 214
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
678-809 6.10e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 84.29  E-value: 6.10e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 678 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 757
Cdd:COG0457    9 EAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQA 88

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 119620631 758 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELE 809
Cdd:COG0457   89 LGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 678-810 1.29e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 74.46  E-value: 1.29e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 678 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 757
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 119620631 758 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEA 810
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 646-815 1.88e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 74.38  E-value: 1.88e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 646 IAASRLEEAMSELtmpSSVLKQGPMQlwttlEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKG 725
Cdd:COG2956   87 LKAGLLDRAEELL---EKLLELDPDD-----AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQG 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 726 NLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTA 805
Cdd:COG2956  159 DYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKA 238

                        170
                 ....*....|
gi 119620631 806 LELEASSPVL 815
Cdd:COG2956  239 LELDPSDDLL 248
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
678-810 2.87e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 73.50  E-value: 2.87e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 678 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 757
Cdd:COG0457   43 EALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLE 122

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 119620631 758 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEA 810
Cdd:COG0457  123 LGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAAL 175
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
706-813 3.31e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 73.12  E-value: 3.31e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 706 LFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGL 785
Cdd:COG0457    3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                         90       100
                 ....*....|....*....|....*...
gi 119620631 786 GEVLQAQGQNEAAVDCFLTALELEASSP 813
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELDPDDA 110
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 677-809 7.38e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.84  E-value: 7.38e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 677 EQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLS 756
Cdd:COG2956   76 AEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYL 155

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 119620631 757 RLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELE 809
Cdd:COG2956  156 EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQD 208
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 676-813 7.83e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 75.41  E-value: 7.83e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 676 LEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLML 755
Cdd:COG3914   43 LALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLL 122

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 119620631 756 SRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSP 813
Cdd:COG3914  123 LALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNA 180
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 712-813 5.03e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 67.14  E-value: 5.03e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 712 SVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQA 791
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                         90       100
                 ....*....|....*....|..
gi 119620631 792 QGQNEAAVDCFLTALELEASSP 813
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHP 106
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 677-807 1.81e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 68.60  E-value: 1.81e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 677 EQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLS 756
Cdd:COG2956  144 AHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYE 223

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 119620631 757 RLGHKSLAQKVLRDAVERQSTcHEAWQGLGEVLQAQGQNEAAVDCFLTALE 807
Cdd:COG2956  224 KLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLR 273
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 676-809 1.23e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 63.44  E-value: 1.23e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 676 LEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRgrlaevKGNLEEAKQLYKEALTVNPDGVRIMHSLGLML 755
Cdd:COG5010   25 EKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNK------LGDFEESLALLEQALQLDPNNPELYYNLALLY 98

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 119620631 756 SRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELE 809
Cdd:COG5010   99 SRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 695-808 1.39e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 62.72  E-value: 1.39e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 695 EAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVER 774
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 119620631 775 QSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALEL 808
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 680-808 6.24e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.98  E-value: 6.24e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 680 WLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLG 759
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 119620631 760 HKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALEL 808
Cdd:COG2956   91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 678-813 2.62e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 62.05  E-value: 2.62e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 678 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 757
Cdd:COG2956   43 EAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQ 122

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 119620631 758 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSP 813
Cdd:COG2956  123 EGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCA 178
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
724-811 4.54e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 57.10  E-value: 4.54e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 724 KGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKvLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFL 803
Cdd:COG3063    5 LGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLE 83


                 ....*...
gi 119620631 804 TALELEAS 811
Cdd:COG3063   84 RALELDPS 91
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 678-819 7.16e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.70  E-value: 7.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 678 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 757
Cdd:COG3914  113 EALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQD 192

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 119620631 758 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVL-PFSI 819
Cdd:COG3914  193 LGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSELsPFAL 255
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 715-813 2.06e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 59.36  E-value: 2.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 715 YMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQ 794
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90
                 ....*....|....*....
gi 119620631 795 NEAAVDCFLTALELEASSP 813
Cdd:COG2956   92 LDRAEELLEKLLELDPDDA 110
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 678-774 4.10e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.40  E-value: 4.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 678 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 757
Cdd:COG4235   18 EGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQ 97

                         90
                 ....*....|....*..
gi 119620631 758 LGHKSLAQKVLRDAVER 774
Cdd:COG4235   98 QGDYAEAIAAWQKLLAL 114
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 570-821 5.24e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 56.53  E-value: 5.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  570 FTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGGLEKDGSFGEGlTMKKQSGMHLTLPDAhDADSGSRRASSIAAS 649
Cdd:TIGR00990 242 FAESKAKEILETKPENLPSVTFVGNYLQSFRPKPRPAGLEDSNELDEE-TGNGQLQLGLKSPES-KADESYEEAARAFEK 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  650 RLE-------EAMS-ELTMPSSVLKQGP----------MQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSH 711
Cdd:TIGR00990 320 ALDlgklgekEAIAlNLRGTFKCLKGKHlealadlsksIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDP 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  712 SVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQA 791
Cdd:TIGR00990 400 DIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLD 479

                         250       260       270
                  ....*....|....*....|....*....|
gi 119620631  792 QGQNEAAVDCFLTALELEASSPVLPFSIIP 821
Cdd:TIGR00990 480 QNKFDEAIEKFDTAIELEKETKPMYMNVLP 509
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
686-775 7.90e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.55  E-value: 7.90e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 686 LFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQlYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQ 765
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|
gi 119620631 766 KVLRDAVERQ 775
Cdd:COG3063   80 AYLERALELD 89
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 426-595 7.38e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 52.69  E-value: 7.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 426 GSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQATDATLKSKQDelHRKALQTLERAQQLAPSDPQVILYVS 505
Cdd:COG3914   42 GLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGR--YEEALALYRRALALNPDNAEALFNLG 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 506 LQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEA 585
Cdd:COG3914  120 NLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEA 199

                        170
                 ....*....|
gi 119620631 586 LVTCRQVLRL 595
Cdd:COG3914  200 IAAYRRALEL 209
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
738-809 9.85e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.78  E-value: 9.85e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 119620631 738 LTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELE 809
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELD 72
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
671-807 3.69e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 48.76  E-value: 3.69e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 671 QLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHS 750
Cdd:COG4785   67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 119620631 751 LGLMLSRLGHKSLAQKVLRDAVERQSTCHEA--WQGL------------------GEVLQAQGQNEAAVDCFLTALE 807
Cdd:COG4785  147 RGIALYYLGRYELAIADLEKALELDPNDPERalWLYLaerkldpekalallledwATAYLLQGDTEEARELFKLALA 223
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 358-594 4.86e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.96  E-value: 4.86e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 358 RRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWlEEAEHF 437
Cdd:COG2956   54 RRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDW-EKAIEV 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 438 AMMVISLGEEAGEFlpkgYLALGLTYslqatdatLKSKQDElhrKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSA 517
Cdd:COG2956  133 LERLLKLGPENAHA----YCELAELY--------LEQGDYD---EAIEALEKALKLDPDCARALLLLAELYLEQGDYEEA 197

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 119620631 518 MEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENfNLMFTKVKLEQVLKGPEEALVTCRQVLR 594
Cdd:COG2956  198 IAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALLERQLR 273
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
714-813 2.18e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.45  E-value: 2.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 714 LYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQG 793
Cdd:COG4785   76 YYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLG 155

                         90       100
                 ....*....|....*....|
gi 119620631 794 QNEAAVDCFLTALELEASSP 813
Cdd:COG4785  156 RYELAIADLEKALELDPNDP 175
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 729-813 3.02e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.23  E-value: 3.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 729 EAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALEL 808
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                 ....*
gi 119620631 809 EASSP 813
Cdd:COG4235   81 DPDNP 85
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 678-744 4.20e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.84  E-value: 4.20e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 119620631 678 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDG 744
Cdd:COG4235   52 DALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 383-595 4.55e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 45.88  E-value: 4.55e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 383 WYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWlEEAEHFAMMVISLGEEAgeflPKGYLALGLT 462
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEY-DRAIRIHQKLLERDPDR----AEALLELAQD 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 463 Y--------------SLQATDATLKSKQDEL---------HRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAME 519
Cdd:COG2956   86 YlkaglldraeelleKLLELDPDDAEALRLLaeiyeqegdWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIE 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 119620631 520 QLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRL 595
Cdd:COG2956  166 ALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALEL 241
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 472-814 5.11e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 5.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  472 LKSKQDElhrKALQTLERAQQLAPSDPQViLYVSLQLALVR-QISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQH 550
Cdd:TIGR02917 238 IEAGEFE---EAEKHADALLKKAPNSPLA-HYLKALVDFQKkNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQ 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  551 ALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGG---------------LEKDGSFG 615
Cdd:TIGR02917 314 AYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGeaylalgdfekaaeyLAKATELD 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  616 EGLTMKK-QSGM-HLTLPDAHDADsgsrrASSIAASRLEEAM--SELTMPSSVLKQGPM------------------QLW 673
Cdd:TIGR02917 394 PENAAARtQLGIsKLSQGDPSEAI-----ADLETAAQLDPELgrADLLLILSYLRSGQFdkalaaakklekkqpdnaSLH 468

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  674 TTLEQIWLQAAELFMEQQHLKEAgfcIQEAAGLFPTSHSVLymrgRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGL 753
Cdd:TIGR02917 469 NLLGAIYLGKGDLAKAREAFEKA---LSIEPDFFPAAANLA----RIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAG 541

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  754 MLSRLGHKS---------------------------LAQK-------VLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAV 799
Cdd:TIGR02917 542 LYLRTGNEEeavawlekaaelnpqeiepalalaqyyLGKGqlkkalaILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAV 621

                         410
                  ....*....|....*
gi 119620631  800 DCFLTALELEASSPV 814
Cdd:TIGR02917 622 SSFKKLLALQPDSAL 636
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 319-817 1.93e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 1.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  319 ESMATRDVVLSRVPEQEEdrtvslqnAAAIYDLLSItlgRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAY 398
Cdd:TIGR02917 245 EAEKHADALLKKAPNSPL--------AHYLKALVDF---QKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQ 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  399 AVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWLEeaehfAMMVISLGEEAGEFLPKGYLALGLTYsLQATDATlkskqde 478
Cdd:TIGR02917 314 AYQYLNQILKYAPNSHQARRLLASIQLRLGRVDE-----AIATLSPALGLDPDDPAALSLLGEAY-LALGDFE------- 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  479 lhrKALQTLERAQQLAPSDPQVilyvSLQLALVR----QISSAMEQLQEALKVrkDDAHALHLLALLFSAQKHHQ--HAL 552
Cdd:TIGR02917 381 ---KAAEYLAKATELDPENAAA----RTQLGISKlsqgDPSEAIADLETAAQL--DPELGRADLLLILSYLRSGQfdKAL 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  553 DVVNMAITEHPEN---FNLMFTKVKLEQVLKGPEEALvtcRQVLRLWQTlySFSQLGGLEKdgsfgegLTMKKQSgmhlt 629
Cdd:TIGR02917 452 AAAKKLEKKQPDNaslHNLLGAIYLGKGDLAKAREAF---EKALSIEPD--FFPAAANLAR-------IDIQEGN----- 514

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  630 LPDAHD-------ADSGSRRASsIAASRLEEAMSELTMPSSVLKQgPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQE 702
Cdd:TIGR02917 515 PDDAIQrfekvltIDPKNLRAI-LALAGLYLRTGNEEEAVAWLEK-AAELNPQEIEPALALAQYYLGKGQLKKALAILNE 592

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  703 AAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAW 782
Cdd:TIGR02917 593 AADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQ 672

                         490       500       510
                  ....*....|....*....|....*....|....*
gi 119620631  783 QGLGEVLQAQGQNEAAvdcFLTALELEASSPVLPF 817
Cdd:TIGR02917 673 IGLAQLLLAAKRTESA---KKIAKSLQKQHPKAAL 704
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 745-813 2.09e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.10  E-value: 2.09e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119620631 745 VRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSP 813
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEP 72
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 713-774 2.19e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.52  E-value: 2.19e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 119620631 713 VLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRI---MHSLGLMLSRLGHKSLAQKVLRDAVER 774
Cdd:COG1729   32 ALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLELGDYDKARATLEELIKK 96
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 681-774 4.18e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.92  E-value: 4.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  681 LQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGH 760
Cdd:TIGR02917 163 LGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGE 242

                          90
                  ....*....|....
gi 119620631  761 KSLAQKVLRDAVER 774
Cdd:TIGR02917 243 FEEAEKHADALLKK 256
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 343-438 6.52e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.56  E-value: 6.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 343 QNAAAiYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAK 422
Cdd:COG4783   36 DNPEA-FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLAR 114

                         90
                 ....*....|....*.
gi 119620631 423 VCIGSLRWLEEAEHFA 438
Cdd:COG4783  115 AYRALGRPDEAIAALE 130
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 720-814 1.01e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 40.71  E-value: 1.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 720 LAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAV 799
Cdd:COG5010   29 AALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAK 108

                         90
                 ....*....|....*
gi 119620631 800 DCFLTALELEASSPV 814
Cdd:COG5010  109 EYYEKALALSPDNPN 123
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 480-595 1.02e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 1.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 480 HRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAI 559
Cdd:COG4783   20 YDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKAL 99

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 119620631 560 TEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRL 595
Cdd:COG4783  100 KLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 679-808 1.14e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 41.82  E-value: 1.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 679 IWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMrGRLAEvkGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRL 758
Cdd:COG3071  195 LAAAYARALIALGDHDEAERLLREALKRQWDPRLVRLY-GRLQG--GDPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRN 271

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 119620631 759 GHKSLAQKVLRDAVERQSTChEAWQGLGEVLQAQGQNEAAVDCFLTALEL 808
Cdd:COG3071  272 QLWGKAREYLEAALALRPSA-EAYAELARLLEQLGDPEEAAEHYRKALAL 320
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 713-808 1.20e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.38  E-value: 1.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  713 VLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQ 792
Cdd:TIGR02917 127 LLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSL 206

                          90
                  ....*....|....*.
gi 119620631  793 GQNEAAVDCFLTALEL 808
Cdd:TIGR02917 207 GNIELALAAYRKAIAL 222
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 344-437 1.54e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.90  E-value: 1.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 344 NAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKV 423
Cdd:COG3914  110 DNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNA 189

                         90
                 ....*....|....
gi 119620631 424 CIGSLRWLEEAEHF 437
Cdd:COG3914  190 LQDLGRLEEAIAAY 203
TPR_11 pfam13414
TPR repeat;
724-759 1.67e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 1.67e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 119620631  724 KGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLG 759
Cdd:pfam13414   7 QGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 453-577 2.22e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.83  E-value: 2.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 453 PKGYLALGLTYSLQatdatlkskqdELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVRKDDA 532
Cdd:COG4235   17 AEGWLLLGRAYLRL-----------GRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 119620631 533 HALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQ 577
Cdd:COG4235   86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAE 130
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
344-553 2.47e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 40.38  E-value: 2.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 344 NAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKV 423
Cdd:COG0457    6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 424 CIgSLRWLEEAEHFAMMVISLGEEagefLPKGYLALGLTYSLQatdatlkskqdELHRKALQTLERAQQLAPSDPQVILY 503
Cdd:COG0457   86 LQ-ALGRYEEALEDYDKALELDPD----DAEALYNLGLALLEL-----------GRYDEAIEAYERALELDPDDADALYN 149

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 119620631 504 VSLQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALD 553
Cdd:COG0457  150 LGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLAL 199
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
431-594 3.06e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 40.38  E-value: 3.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 431 LEEAEHFAMMVISLGEEagefLPKGYLALGLTYSLQatdatlkskqdELHRKALQTLERAQQLAPSDPQVILYVSLQLAL 510
Cdd:COG0457   24 YEEAIEDYEKALELDPD----DAEALYNLGLAYLRL-----------GRYEEALADYEQALELDPDDAEALNNLGLALQA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 511 VRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCR 590
Cdd:COG0457   89 LGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLE 168


                 ....
gi 119620631 591 QVLR 594
Cdd:COG0457  169 KLEA 172
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 384-809 3.12e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.22  E-value: 3.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  384 YQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWLEEAEHFammvislgeEAGEFLPKGYLALGLTY 463
Cdd:TIGR02917  60 FLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQVLDEL---------PGKTLLDDEGAAELLAL 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  464 slqATDATLKSKQDElhrKALQTLERAQQLAPSDpqviLYVSLQLAlvrQISSAMEQLQEALKvrkddahalhllallfs 543
Cdd:TIGR02917 131 ---RGLAYLGLGQLE---LAQKSYEQALAIDPRS----LYAKLGLA---QLALAENRFDEARA----------------- 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  544 aqkhhqhaldVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRLwqtlysfsqlgglekdgsfgegltmkkq 623
Cdd:TIGR02917 181 ----------LIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIAL---------------------------- 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  624 sgmHLTLPDAHDADSGSRrassIAASRLEEAMSELTmpsSVLKQGPMQLWTTleqiWLQAAELFMEQQHlKEAGFCIQEA 703
Cdd:TIGR02917 223 ---RPNNIAVLLALATIL----IEAGEFEEAEKHAD---ALLKKAPNSPLAH----YLKALVDFQKKNY-EDARETLQDA 287

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631  704 AGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQ 783
Cdd:TIGR02917 288 LKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALS 367

                         410       420
                  ....*....|....*....|....*.
gi 119620631  784 GLGEVLQAQGQNEAAVDCFLTALELE 809
Cdd:TIGR02917 368 LLGEAYLALGDFEKAAEYLAKATELD 393
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 713-743 3.59e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.58  E-value: 3.59e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 119620631  713 VLYMRGRLAEVKGNLEEAKQLYKEALTVNPD 743
Cdd:pfam07719   3 ALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
525-775 4.26e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.60  E-value: 4.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 525 LKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRLwqtlysfsq 604
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL--------- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 605 lgglekdgsfgegltmkkqsgmhltlpDAHDAdsgsrrassiaasrleeamseltmpssvlkqgpmqlwttleQIWLQAA 684
Cdd:COG0457   72 ---------------------------DPDDA-----------------------------------------EALNNLG 83

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 685 ELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLA 764
Cdd:COG0457   84 LALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEA 163

                        250
                 ....*....|.
gi 119620631 765 QKVLRDAVERQ 775
Cdd:COG0457  164 LELLEKLEAAA 174
TPR_1 pfam00515
Tetratricopeptide repeat;
713-743 4.97e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.09  E-value: 4.97e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 119620631  713 VLYMRGRLAEVKGNLEEAKQLYKEALTVNPD 743
Cdd:pfam00515   3 ALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
678-743 5.68e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.07  E-value: 5.68e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 119620631 678 QIWLQAAELFMEQQHLKEAgFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPD 743
Cdd:COG3063   27 DALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 678-743 6.08e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.86  E-value: 6.08e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 119620631 678 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPD 743
Cdd:COG4783   73 EARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 482-565 7.50e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.48  E-value: 7.50e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620631 482 KALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITE 561
Cdd:COG4783   56 EAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135


                 ....
gi 119620631 562 HPEN 565
Cdd:COG4783  136 DPDD 139
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH