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Conserved domains on  [gi|123984987|gb|EAY24945|]
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conserved hypothetical protein [Microscilla marina ATCC 23134]

Protein Classification

DUF1987 domain-containing protein( domain architecture ID 10558573)

DUF1987 domain-containing protein similar to Pseudomonas aeruginosa uncharacterized protein PA14_02130

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SiaC pfam09345
SiaC family regulatory phosphoprotein; This entry represents the SiaC family regulatory ...
 6-124 8.86e-48

SiaC family regulatory phosphoprotein; This entry represents the SiaC family regulatory phosphoprotein which undergoes a regulatory phosphorylation at Thr-68 of founder protein PA0170 from Pseudomonas aeruginosa, but in more distant homologs, T can be S. Also, it is part of motif NTSS, so may contain more than one phosphorylation site. Phosphorylation causes regulatory change to protein-protein interaction, in a pathway that seems broadly distributed, involves a diguanylate cyclase, and in the case of Pseudomonas aeruginosa affects aggregation and biofilm formation responses.


:

Pssm-ID: 430544  Cd Length: 121  Bit Score: 149.57  E-value: 8.86e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 123984987    6 IAEKHDTPQVSFDANTKVFEISGESFSEYSMDFYLPIIQWIDAYTKQYEG-PITFNFKLLYYNTGSSQRLLEIMQMLDQY 84
Cdd:pfam09345   1 IEATKSTPEVDFDAETGILEISGESYPENAFEFYGPILDWLEAYLEAPNDkPITVNFKLSYFNTSSSKALMDLFDLLEDA 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 123984987   85 HNSGKgQVKINWYSLPEEYRMIEAGEDYQATLK-VPFEIIE 124
Cdd:pfam09345  81 AEKGG-KVTVNWYYDEDDEDMLELGEDFKEDFTlLPFNIIP 120
 
Name Accession Description Interval E-value
SiaC pfam09345
SiaC family regulatory phosphoprotein; This entry represents the SiaC family regulatory ...
 6-124 8.86e-48

SiaC family regulatory phosphoprotein; This entry represents the SiaC family regulatory phosphoprotein which undergoes a regulatory phosphorylation at Thr-68 of founder protein PA0170 from Pseudomonas aeruginosa, but in more distant homologs, T can be S. Also, it is part of motif NTSS, so may contain more than one phosphorylation site. Phosphorylation causes regulatory change to protein-protein interaction, in a pathway that seems broadly distributed, involves a diguanylate cyclase, and in the case of Pseudomonas aeruginosa affects aggregation and biofilm formation responses.


Pssm-ID: 430544  Cd Length: 121  Bit Score: 149.57  E-value: 8.86e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 123984987    6 IAEKHDTPQVSFDANTKVFEISGESFSEYSMDFYLPIIQWIDAYTKQYEG-PITFNFKLLYYNTGSSQRLLEIMQMLDQY 84
Cdd:pfam09345   1 IEATKSTPEVDFDAETGILEISGESYPENAFEFYGPILDWLEAYLEAPNDkPITVNFKLSYFNTSSSKALMDLFDLLEDA 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 123984987   85 HNSGKgQVKINWYSLPEEYRMIEAGEDYQATLK-VPFEIIE 124
Cdd:pfam09345  81 AEKGG-KVTVNWYYDEDDEDMLELGEDFKEDFTlLPFNIIP 120
 
Name Accession Description Interval E-value
SiaC pfam09345
SiaC family regulatory phosphoprotein; This entry represents the SiaC family regulatory ...
 6-124 8.86e-48

SiaC family regulatory phosphoprotein; This entry represents the SiaC family regulatory phosphoprotein which undergoes a regulatory phosphorylation at Thr-68 of founder protein PA0170 from Pseudomonas aeruginosa, but in more distant homologs, T can be S. Also, it is part of motif NTSS, so may contain more than one phosphorylation site. Phosphorylation causes regulatory change to protein-protein interaction, in a pathway that seems broadly distributed, involves a diguanylate cyclase, and in the case of Pseudomonas aeruginosa affects aggregation and biofilm formation responses.


Pssm-ID: 430544  Cd Length: 121  Bit Score: 149.57  E-value: 8.86e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 123984987    6 IAEKHDTPQVSFDANTKVFEISGESFSEYSMDFYLPIIQWIDAYTKQYEG-PITFNFKLLYYNTGSSQRLLEIMQMLDQY 84
Cdd:pfam09345   1 IEATKSTPEVDFDAETGILEISGESYPENAFEFYGPILDWLEAYLEAPNDkPITVNFKLSYFNTSSSKALMDLFDLLEDA 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 123984987   85 HNSGKgQVKINWYSLPEEYRMIEAGEDYQATLK-VPFEIIE 124
Cdd:pfam09345  81 AEKGG-KVTVNWYYDEDDEDMLELGEDFKEDFTlLPFNIIP 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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