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Conserved domains on  [gi|148690491|gb|EDL22438|]
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CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae), isoform CRA_b, partial [Mus musculus]

Protein Classification

HLD_clamp_RFC domain-containing protein( domain architecture ID 13031126)

HLD_clamp_RFC domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
 1-51 1.49e-08

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


:

Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 50.99  E-value: 1.49e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 148690491   1 ISLQHGMRSDPGALVALCEKTDNDIRACINTLQFLYgRGRRELSVKAVQTT 51
Cdd:cd18140   13 ICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAA-AGGGVITEEDVYEV 62
 
Name Accession Description Interval E-value
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
 1-51 1.49e-08

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 50.99  E-value: 1.49e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 148690491   1 ISLQHGMRSDPGALVALCEKTDNDIRACINTLQFLYgRGRRELSVKAVQTT 51
Cdd:cd18140   13 ICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAA-AGGGVITEEDVYEV 62
PRK04195 PRK04195
replication factor C large subunit; Provisional
 1-70 1.46e-04

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 44.14  E-value: 1.46e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690491   1 ISLQHGMRSDPGALVALCEKTDNDIRACINTLQFLyGRGRRELSVKAVQTthVGLKDQRKGLFSVWQEVF 70
Cdd:PRK04195 172 ICRKEGIECDDEALKEIAERSGGDLRSAINDLQAI-AEGYGKLTLEDVKT--LGRRDREESIFDALDAVF 238
 
Name Accession Description Interval E-value
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
 1-51 1.49e-08

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 50.99  E-value: 1.49e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 148690491   1 ISLQHGMRSDPGALVALCEKTDNDIRACINTLQFLYgRGRRELSVKAVQTT 51
Cdd:cd18140   13 ICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAA-AGGGVITEEDVYEV 62
PRK04195 PRK04195
replication factor C large subunit; Provisional
 1-70 1.46e-04

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 44.14  E-value: 1.46e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690491   1 ISLQHGMRSDPGALVALCEKTDNDIRACINTLQFLyGRGRRELSVKAVQTthVGLKDQRKGLFSVWQEVF 70
Cdd:PRK04195 172 ICRKEGIECDDEALKEIAERSGGDLRSAINDLQAI-AEGYGKLTLEDVKT--LGRRDREESIFDALDAVF 238
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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